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Illumina Body Map 2 (GSE30611)

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Results for RREB1

Z-value: 0.95

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Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
ENSG00000124782.20 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg38_v1_chr6_+_7107941_71080310.551.2e-03Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52680398 2.72 ENST00000252244.3
keratin 1
chr17_+_43847168 2.41 ENST00000317310.5
CD300 molecule like family member g
chr17_+_43847142 2.22 ENST00000377203.8
ENST00000539718.5
ENST00000588884.1
ENST00000293396.12
ENST00000586233.5
CD300 molecule like family member g
chr10_+_17229267 1.96 ENST00000224237.9
vimentin
chr10_+_113679159 1.91 ENST00000621345.4
ENST00000429617.5
ENST00000369331.8
caspase 7
chr10_+_17228806 1.79 ENST00000497849.1
vimentin
chr1_+_170663134 1.69 ENST00000367760.7
paired related homeobox 1
chr8_+_37695774 1.66 ENST00000331569.6
zinc finger protein 703
chr12_+_54008961 1.57 ENST00000040584.6
homeobox C8
chrX_+_151912878 1.54 ENST00000276344.6
MAGE family member A4
chr16_+_397209 1.45 ENST00000382940.8
NME/NM23 nucleoside diphosphate kinase 4
chr17_-_41521719 1.44 ENST00000393976.6
keratin 15
chr12_-_7936177 1.41 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chr17_+_60422483 1.38 ENST00000269127.5
chromosome 17 open reading frame 64
chrX_-_120115909 1.35 ENST00000217999.3
Rhox homeobox family member 1
chr11_+_1876467 1.31 ENST00000432093.1
lymphocyte specific protein 1
chr16_+_21158653 1.22 ENST00000572258.5
ENST00000233047.9
ENST00000261388.7
ENST00000451578.6
ENST00000572599.5
ENST00000577162.1
transmembrane protein 159
chr1_+_101238090 1.21 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr2_-_127675065 1.20 ENST00000545738.6
ENST00000409808.6
LIM zinc finger domain containing 2
chr19_+_14433384 1.20 ENST00000586557.5
ENST00000590097.5
protein kinase N1
chr11_+_818906 1.19 ENST00000336615.9
patatin like phospholipase domain containing 2
chr16_+_397226 1.18 ENST00000433358.5
NME/NM23 nucleoside diphosphate kinase 4
chr15_-_43220989 1.17 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
erythrocyte membrane protein band 4.2
chr19_+_55488404 1.15 ENST00000594321.5
ENST00000389623.11
scavenger receptor cysteine rich family member with 5 domains
chr19_+_55488549 1.14 ENST00000587166.5
scavenger receptor cysteine rich family member with 5 domains
chrX_+_151912458 1.13 ENST00000431963.6
ENST00000682265.1
MAGE family member A4
chr14_+_103121457 1.09 ENST00000333007.8
TNF alpha induced protein 2
chr12_+_53990585 1.08 ENST00000504315.1
homeobox C6
chr19_+_14433284 1.07 ENST00000242783.11
protein kinase N1
chr2_-_127675459 1.07 ENST00000355119.9
LIM zinc finger domain containing 2
chr18_-_46559289 1.04 ENST00000419859.1
ENST00000582408.6
ENST00000300591.11
lipoxygenase homology domains 1
chr2_+_46542474 1.04 ENST00000238738.9
ras homolog family member Q
chr2_-_136116165 1.03 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr1_-_16980607 1.02 ENST00000375535.4
microfibril associated protein 2
chr15_+_75206398 1.00 ENST00000565074.1
chromosome 15 open reading frame 39
chr5_+_136047319 0.99 ENST00000508767.5
ENST00000604555.5
transforming growth factor beta induced
chr13_-_71867192 0.97 ENST00000611519.4
ENST00000620444.4
ENST00000613252.5
dachshund family transcription factor 1
chr12_-_55707865 0.97 ENST00000347027.10
ENST00000257879.11
ENST00000553804.6
integrin subunit alpha 7
chr7_-_128405930 0.97 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
inosine monophosphate dehydrogenase 1
chr3_-_41961989 0.97 ENST00000420927.5
ENST00000301831.9
ENST00000414606.1
unc-51 like kinase 4
chr2_+_48530132 0.96 ENST00000404752.6
ENST00000406226.1
stonin 1
chr9_+_129665603 0.95 ENST00000372469.6
paired related homeobox 2
chr11_-_22860467 0.94 ENST00000532798.3
coiled-coil domain containing 179
chr19_-_50953093 0.92 ENST00000593428.5
kallikrein related peptidase 5
chr17_+_60149966 0.91 ENST00000300900.9
carbonic anhydrase 4
chr17_+_40318237 0.90 ENST00000394089.6
ENST00000425707.7
retinoic acid receptor alpha
chr3_+_155079847 0.89 ENST00000615825.2
membrane metalloendopeptidase
chr12_+_54053815 0.87 ENST00000430889.3
homeobox C4
chr11_-_57322197 0.87 ENST00000532437.1
tankyrase 1 binding protein 1
chr10_-_3785197 0.87 ENST00000497571.6
Kruppel like factor 6
chr19_-_50952942 0.87 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr19_+_6135635 0.86 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
acyl-CoA synthetase bubblegum family member 2
chr20_+_4721901 0.85 ENST00000305817.3
prion like protein doppel
chr11_+_1099730 0.85 ENST00000674892.1
mucin 2, oligomeric mucus/gel-forming
chr4_-_153789057 0.84 ENST00000274063.5
secreted frizzled related protein 2
chr19_-_50953063 0.83 ENST00000391809.6
kallikrein related peptidase 5
chr16_+_28878480 0.82 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_9265078 0.82 ENST00000530044.5
ENST00000679568.1
ENST00000680294.1
ENST00000681203.1
DENN domain containing 5A
chr19_+_35118456 0.81 ENST00000604621.5
FXYD domain containing ion transport regulator 3
chr21_+_36135071 0.80 ENST00000290354.6
carbonyl reductase 3
chr3_+_193241128 0.80 ENST00000650797.1
phospholipase A and acyltransferase 1
chr16_+_397183 0.80 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME/NM23 nucleoside diphosphate kinase 4
chr17_+_60149928 0.80 ENST00000591725.1
carbonic anhydrase 4
chr1_-_183569186 0.79 ENST00000420553.5
ENST00000419402.1
neutrophil cytosolic factor 2
chr19_-_15449920 0.79 ENST00000263381.12
ENST00000643092.1
ENST00000673675.1
WIZ zinc finger
chr11_+_7485492 0.78 ENST00000534244.1
ENST00000329293.4
olfactomedin like 1
chr16_-_67483541 0.78 ENST00000290953.3
agouti related neuropeptide
chrX_-_152769677 0.77 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGE family member A6
chr10_-_101843777 0.77 ENST00000356640.7
potassium voltage-gated channel interacting protein 2
chr3_+_155079663 0.77 ENST00000460393.6
membrane metalloendopeptidase
chr12_-_57251169 0.77 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
SH3 and cysteine rich domain 3
chr3_+_155079911 0.76 ENST00000675418.2
membrane metalloendopeptidase
chr11_-_9265302 0.76 ENST00000328194.8
DENN domain containing 5A
chr2_+_28395511 0.75 ENST00000436647.1
FOS like 2, AP-1 transcription factor subunit
chr11_+_7485606 0.75 ENST00000528758.1
olfactomedin like 1
chr16_+_28878382 0.75 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr19_+_45506579 0.74 ENST00000589627.1
vasodilator stimulated phosphoprotein
chr10_-_3785225 0.74 ENST00000542957.1
Kruppel like factor 6
chr17_+_40140500 0.72 ENST00000264645.12
CASC3 exon junction complex subunit
chr3_+_155080111 0.72 ENST00000493237.5
membrane metalloendopeptidase
chr1_+_77888490 0.72 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr12_+_53985065 0.71 ENST00000515593.1
homeobox C10
chr10_-_3785179 0.71 ENST00000469435.1
Kruppel like factor 6
chr12_-_120250145 0.70 ENST00000458477.6
paxillin
chr17_+_7023042 0.69 ENST00000293805.10
BCL6B transcription repressor
chr12_+_6828377 0.69 ENST00000290510.10
prolyl 3-hydroxylase 3
chrX_+_152698767 0.68 ENST00000417212.5
ENST00000598245.2
ENST00000370278.4
MAGE family member A3
chr10_-_101843765 0.68 ENST00000370046.5
potassium voltage-gated channel interacting protein 2
chr9_-_34126661 0.68 ENST00000361264.9
DDB1 and CUL4 associated factor 12
chr11_+_128693887 0.68 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr9_+_35906179 0.68 ENST00000354323.3
histidine rich carboxyl terminus 1
chr19_+_40799707 0.67 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
ENST00000593525.1
egl-9 family hypoxia inducible factor 2
chr10_-_101843920 0.67 ENST00000358038.7
potassium voltage-gated channel interacting protein 2
chr1_+_109548567 0.67 ENST00000369851.7
G protein subunit alpha i3
chr12_-_57129001 0.66 ENST00000556155.5
signal transducer and activator of transcription 6
chr13_-_71866769 0.66 ENST00000619232.1
dachshund family transcription factor 1
chr17_+_2055094 0.66 ENST00000399849.4
ENST00000619757.5
HIC ZBTB transcriptional repressor 1
chr19_+_40799425 0.66 ENST00000593972.1
egl-9 family hypoxia inducible factor 2
chrX_-_152753840 0.65 ENST00000617505.1
ENST00000684311.1
ENST00000617846.4
ENST00000595583.5
ENST00000620710.4
ENST00000611557.4
ENST00000623806.3
ENST00000623438.3
ENST00000598543.5
ENST00000611674.4
MAGE family member A2
chrX_+_149781930 0.64 ENST00000243314.5
MAGE family member A9
chr19_+_48364361 0.64 ENST00000344846.7
synaptogyrin 4
chr14_-_105168753 0.64 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr10_+_100998348 0.63 ENST00000429732.5
leucine zipper tumor suppressor 2
chr4_-_77074879 0.63 ENST00000505609.5
cyclin I
chr11_+_7485353 0.63 ENST00000530135.5
olfactomedin like 1
chr3_+_155080088 0.62 ENST00000462745.5
membrane metalloendopeptidase
chr20_+_43667019 0.62 ENST00000396863.8
MYB proto-oncogene like 2
chr11_-_57322300 0.62 ENST00000527207.1
tankyrase 1 binding protein 1
chr1_+_61082553 0.62 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr11_+_847197 0.61 ENST00000532375.5
ENST00000346501.8
tetraspanin 4
chr16_-_3235143 0.61 ENST00000414144.7
ENST00000431561.7
ENST00000396870.8
zinc finger protein 200
chr16_-_31428325 0.61 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr6_+_7107597 0.61 ENST00000379933.7
ENST00000491191.5
ENST00000471433.5
ras responsive element binding protein 1
chr1_-_112707314 0.60 ENST00000369642.7
ras homolog family member C
chr16_-_88941801 0.60 ENST00000569464.5
ENST00000569443.5
CBFA2/RUNX1 partner transcriptional co-repressor 3
chrX_-_149587444 0.60 ENST00000593349.5
ENST00000602102.5
ENST00000595065.6
MAGE family member A9B
chr11_+_86800527 0.60 ENST00000280258.6
serine protease 23
chr3_-_138115594 0.59 ENST00000327532.7
ENST00000467030.5
DAZ interacting zinc finger protein 1 like
chr10_-_33334898 0.59 ENST00000395995.5
neuropilin 1
chr4_-_77819356 0.59 ENST00000649644.1
ENST00000504123.6
ENST00000515441.2
CCR4-NOT transcription complex subunit 6 like
chr4_+_163343882 0.58 ENST00000338566.8
neuropeptide Y receptor Y5
chr10_-_33334625 0.57 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr2_+_191678152 0.56 ENST00000409510.5
nucleic acid binding protein 1
chr6_+_151325665 0.56 ENST00000354675.10
A-kinase anchoring protein 12
chr20_+_43667105 0.56 ENST00000217026.5
MYB proto-oncogene like 2
chr20_+_58689124 0.56 ENST00000525967.5
ENST00000525817.5
aminopeptidase like 1
chr8_-_144354845 0.55 ENST00000562477.1
ENST00000565365.1
transmembrane protein 249
chr2_+_218400039 0.55 ENST00000452977.5
CTD small phosphatase 1
chr19_+_40799155 0.55 ENST00000303961.9
egl-9 family hypoxia inducible factor 2
chr2_+_120735848 0.55 ENST00000361492.9
GLI family zinc finger 2
chr8_+_26291758 0.54 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr20_-_3712564 0.53 ENST00000344754.6
sialic acid binding Ig like lectin 1
chr10_+_100998676 0.53 ENST00000481129.1
leucine zipper tumor suppressor 2
chr14_-_68978240 0.52 ENST00000556571.1
ENST00000553659.1
ENST00000555616.5
actinin alpha 1
chr1_-_112707056 0.52 ENST00000369633.6
ENST00000425265.6
ENST00000369632.6
ENST00000436685.6
ENST00000484054.3
ENST00000369636.6
ENST00000369637.5
ENST00000339083.12
ENST00000285735.6
ENST00000369638.6
ras homolog family member C
chr5_-_180803830 0.52 ENST00000427865.2
ENST00000514283.1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr17_+_79778135 0.51 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr10_-_33334382 0.51 ENST00000374823.9
ENST00000374821.9
ENST00000374816.7
neuropilin 1
chr2_-_37324826 0.50 ENST00000234179.8
protein kinase D3
chr15_+_63189554 0.50 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr21_+_42653734 0.49 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
phosphodiesterase 9A
chr9_+_133348207 0.49 ENST00000323345.11
ENST00000426651.1
ribosomal protein L7a
chr19_+_40799501 0.49 ENST00000406058.6
ENST00000593726.5
egl-9 family hypoxia inducible factor 2
chr19_+_50854910 0.48 ENST00000601503.5
ENST00000326003.7
ENST00000617027.4
ENST00000597286.5
ENST00000597483.5
ENST00000593997.5
kallikrein related peptidase 3
chr1_-_1779976 0.48 ENST00000378625.5
NAD kinase
chr1_-_23531206 0.48 ENST00000361729.3
E2F transcription factor 2
chrX_+_152714586 0.47 ENST00000331220.6
ENST00000370293.6
ENST00000423993.5
ENST00000447530.5
ENST00000682532.1
ENST00000458057.5
ENST00000422085.5
ENST00000453150.5
ENST00000409560.1
MAGE family member A2B
chr17_+_60421697 0.47 ENST00000474834.5
chromosome 17 open reading frame 64
chr16_+_30075967 0.46 ENST00000279387.12
ENST00000562664.5
ENST00000627746.2
ENST00000562222.5
protein phosphatase 4 catalytic subunit
chrX_-_154751017 0.46 ENST00000369575.7
ENST00000369568.8
ENST00000424127.3
GRB2 associated binding protein 3
chr12_-_47820562 0.46 ENST00000433685.5
ENST00000447463.5
ENST00000427332.6
histone deacetylase 7
chr19_+_35666515 0.46 ENST00000617999.4
ENST00000616789.4
uroplakin 1A
chr2_-_219243577 0.46 ENST00000409640.5
galactosidase beta 1 like
chr19_+_41877267 0.46 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr1_+_61082702 0.45 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr1_+_61082398 0.45 ENST00000664149.1
nuclear factor I A
chr13_+_60397214 0.45 ENST00000377881.8
tudor domain containing 3
chr20_+_57392064 0.45 ENST00000371219.2
RNA binding motif protein 38
chr10_-_13528971 0.44 ENST00000466271.2
BEN domain containing 7
chr21_-_34887148 0.44 ENST00000399240.5
RUNX family transcription factor 1
chr18_-_47930322 0.44 ENST00000587421.5
SMAD family member 2
chr2_-_144520106 0.44 ENST00000627532.3
ENST00000539609.7
zinc finger E-box binding homeobox 2
chr19_+_40799796 0.44 ENST00000596517.1
egl-9 family hypoxia inducible factor 2
chr12_-_54588636 0.44 ENST00000257905.13
protein phosphatase 1 regulatory inhibitor subunit 1A
chr17_+_64449037 0.44 ENST00000615220.4
ENST00000619286.5
ENST00000612535.4
ENST00000616498.4
mast cell immunoglobulin like receptor 1
chr11_-_35525603 0.43 ENST00000529303.1
ENST00000619888.5
ENST00000622144.4
peptidase domain containing associated with muscle regeneration 1
chr8_+_141416078 0.43 ENST00000349124.3
protein tyrosine phosphatase 4A3
chrX_-_152138547 0.43 ENST00000577437.1
ENST00000427322.6
ENST00000370323.9
ENST00000244096.7
MAGEA10-MAGEA5 readthrough
MAGE family member A10
chr3_+_155079992 0.43 ENST00000382989.7
membrane metalloendopeptidase
chr4_-_124712721 0.43 ENST00000504087.6
ENST00000515641.1
ankyrin repeat domain 50
chr3_+_193241190 0.43 ENST00000264735.4
phospholipase A and acyltransferase 1
chr2_-_144520006 0.43 ENST00000303660.8
zinc finger E-box binding homeobox 2
chr16_+_28822982 0.42 ENST00000336783.9
ENST00000340394.12
ENST00000325215.10
ENST00000382686.8
ENST00000395547.6
ENST00000564304.5
ataxin 2 like
chrX_+_125320120 0.42 ENST00000632600.1
TEX13 family member C
chr6_+_7107941 0.42 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
ras responsive element binding protein 1
chr8_+_141416141 0.42 ENST00000680615.1
protein tyrosine phosphatase 4A3
chr9_-_81689536 0.42 ENST00000376499.8
TLE family member 1, transcriptional corepressor
chr1_+_15756603 0.41 ENST00000496928.6
ENST00000508310.5
filamin binding LIM protein 1
chr18_-_23662766 0.41 ENST00000585908.2
ankyrin repeat domain 29
chr11_+_67119245 0.41 ENST00000529006.7
ENST00000398645.6
lysine demethylase 2A
chr20_+_49982969 0.40 ENST00000244050.3
snail family transcriptional repressor 1
chr19_+_50854938 0.40 ENST00000595952.5
ENST00000360617.7
ENST00000598145.1
kallikrein related peptidase 3
chr3_+_57060658 0.40 ENST00000334325.2
spermatogenesis associated 12
chr11_-_64935882 0.39 ENST00000532246.1
ENST00000279168.7
glycoprotein hormone subunit alpha 2
chr3_+_53161501 0.39 ENST00000487897.5
protein kinase C delta
chr8_+_89902682 0.38 ENST00000520659.1
oxidative stress induced growth inhibitor family member 2
chr12_+_54549586 0.38 ENST00000243052.8
phosphodiesterase 1B
chr19_-_43580434 0.38 ENST00000599693.5
ENST00000598165.5
X-ray repair cross complementing 1
chr10_-_73655984 0.38 ENST00000394810.3
synaptopodin 2 like
chr8_-_73093114 0.38 ENST00000297354.7
somatomedin B and thrombospondin type 1 domain containing
chr2_-_37324696 0.37 ENST00000443187.1
protein kinase D3
chr2_-_61538180 0.37 ENST00000677150.1
ENST00000678182.1
ENST00000677928.1
ENST00000406957.5
exportin 1
chr20_+_836052 0.36 ENST00000246100.3
family with sequence similarity 110 member A
chr19_-_8896090 0.36 ENST00000599436.1
mucin 16, cell surface associated
chr18_-_23662868 0.36 ENST00000586087.1
ENST00000592179.6
ankyrin repeat domain 29
chr19_-_3063101 0.36 ENST00000221561.12
TLE family member 5, transcriptional modulator
chr2_-_85410336 0.35 ENST00000263867.9
ENST00000409921.5
capping actin protein, gelsolin like
chr15_+_76336755 0.35 ENST00000290759.9
ISL LIM homeobox 2
chr3_-_39153512 0.35 ENST00000273153.10
cysteine and serine rich nuclear protein 1
chr3_-_52835011 0.35 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.5 1.6 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.5 2.0 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4 2.6 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.4 2.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.4 2.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 1.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 1.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 0.8 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.3 3.6 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 1.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 1.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 2.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 1.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 2.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 3.7 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 2.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 0.5 GO:0060032 notochord regression(GO:0060032)
0.2 0.9 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.2 4.4 GO:0006183 GTP biosynthetic process(GO:0006183)
0.2 1.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 0.8 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 2.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.9 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.7 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.4 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.1 0.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.4 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.7 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.4 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 1.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.3 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 1.0 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.4 GO:2000754 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.1 1.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.5 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.6 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.9 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 1.3 GO:0051601 exocyst localization(GO:0051601)
0.1 1.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.5 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.7 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.9 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.3 GO:0060584 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0097274 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.1 0.9 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.3 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.8 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.2 GO:0002432 granuloma formation(GO:0002432)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.6 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 1.5 GO:0072189 ureter development(GO:0072189)
0.0 0.7 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.0 0.8 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 1.7 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0010159 specification of organ position(GO:0010159)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.8 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:2000197 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.2 GO:0032848 positive regulation of neuron maturation(GO:0014042) negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.7 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.7 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 1.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.0 0.4 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 1.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 1.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 1.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 2.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.7 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.7 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.1 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.3 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:1901984 negative regulation of protein acetylation(GO:1901984)
0.0 2.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.0 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.5 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.5 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.4 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.8 GO:0070701 mucus layer(GO:0070701)
0.2 2.0 GO:0097443 sorting endosome(GO:0097443)
0.2 1.2 GO:0031523 Myb complex(GO:0031523)
0.1 4.9 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.8 GO:0032010 phagolysosome(GO:0032010)
0.1 0.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 3.0 GO:0001533 cornified envelope(GO:0001533)
0.0 1.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 3.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 1.0 GO:0031143 pseudopodium(GO:0031143)
0.0 3.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 4.2 GO:0005882 intermediate filament(GO:0005882)
0.0 4.0 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 1.1 GO:0008305 integrin complex(GO:0008305)
0.0 4.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.0 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:1990254 keratin filament binding(GO:1990254)
0.4 2.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 0.8 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.3 2.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 0.8 GO:0070984 SET domain binding(GO:0070984)
0.3 1.0 GO:0032427 GBD domain binding(GO:0032427)
0.3 2.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 3.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 3.4 GO:1901612 cardiolipin binding(GO:1901612)
0.2 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 2.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.6 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.4 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 4.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.5 GO:0004803 transposase activity(GO:0004803)
0.1 1.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.9 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 1.0 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.2 GO:0030305 heparanase activity(GO:0030305)
0.1 1.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.6 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 2.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 2.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.5 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 4.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 2.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 1.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.7 PID AURORA B PATHWAY Aurora B signaling
0.0 2.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 4.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 4.1 PID E2F PATHWAY E2F transcription factor network
0.0 2.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 5.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis