Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for RUNX3_BCL11A

Z-value: 3.30

Motif logo

Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
ENSG00000020633.19 RUNX family transcription factor 3
ENSG00000119866.22 BAF chromatin remodeling complex subunit BCL11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX3hg38_v1_chr1_-_24930263_249302820.956.8e-17Click!
BCL11Ahg38_v1_chr2_-_60553409_605534610.551.1e-03Click!

Activity profile of RUNX3_BCL11A motif

Sorted Z-values of RUNX3_BCL11A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_24964984 30.16 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr3_-_151203201 24.18 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr6_+_45328203 23.74 ENST00000371432.7
ENST00000647337.2
ENST00000371438.5
RUNX family transcription factor 2
chr22_+_39901075 23.07 ENST00000344138.9
GRB2 related adaptor protein 2
chr2_-_157444044 22.69 ENST00000264192.8
cytohesin 1 interacting protein
chr5_+_35856883 21.25 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr1_-_113871665 20.91 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr5_+_157180816 20.71 ENST00000422843.8
IL2 inducible T cell kinase
chr5_+_55102635 18.98 ENST00000274306.7
granzyme A
chr4_+_70226116 17.69 ENST00000317987.6
follicular dendritic cell secreted protein
chr11_+_60971668 17.14 ENST00000313421.11
CD6 molecule
chr5_+_134115563 16.69 ENST00000517851.5
ENST00000521639.5
ENST00000522375.5
ENST00000378560.8
ENST00000520958.5
ENST00000518915.5
ENST00000395023.5
transcription factor 7
chr17_+_7336502 15.80 ENST00000158762.8
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chrX_+_48683763 15.58 ENST00000376701.5
WASP actin nucleation promoting factor
chr19_-_42132465 15.38 ENST00000529067.5
ENST00000529952.5
ENST00000342301.8
ENST00000389341.9
POU class 2 homeobox 2
chr11_+_60971777 14.29 ENST00000542157.5
ENST00000433107.6
ENST00000352009.9
ENST00000452451.6
CD6 molecule
chr7_+_142529268 14.22 ENST00000612787.1
T cell receptor beta variable 7-9
chrX_+_37780049 13.62 ENST00000378588.5
cytochrome b-245 beta chain
chr19_-_42132391 13.57 ENST00000528894.8
ENST00000560804.6
ENST00000560558.5
ENST00000560398.5
ENST00000526816.6
ENST00000625670.2
POU class 2 homeobox 2
chr17_+_7336557 13.11 ENST00000570457.6
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chrX_-_49264668 12.78 ENST00000455775.7
ENST00000652559.1
ENST00000376207.10
ENST00000557224.6
ENST00000684155.1
ENST00000376199.7
forkhead box P3
chr17_-_36090133 11.32 ENST00000613922.2
C-C motif chemokine ligand 3
chr1_-_168543990 11.27 ENST00000367819.3
X-C motif chemokine ligand 2
chr14_-_24634160 11.19 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr1_+_209756032 10.63 ENST00000400959.7
ENST00000367025.8
TRAF3 interacting protein 3
chr3_+_114294020 10.36 ENST00000383671.8
T cell immunoreceptor with Ig and ITIM domains
chr4_-_83114715 10.35 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr12_-_10390023 10.13 ENST00000240618.11
killer cell lectin like receptor K1
chr12_-_54300974 10.12 ENST00000435572.7
ENST00000553070.5
nuclear factor, erythroid 2
chr13_-_99258366 9.56 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr22_+_22880706 9.35 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr4_-_108166715 9.28 ENST00000510624.5
lymphoid enhancer binding factor 1
chr17_-_31321603 9.25 ENST00000462804.3
ecotropic viral integration site 2A
chr11_-_128587551 9.06 ENST00000392668.8
ETS proto-oncogene 1, transcription factor
chr1_+_209768597 8.93 ENST00000487271.5
ENST00000477431.1
TRAF3 interacting protein 3
chr17_-_31321743 8.91 ENST00000247270.3
ecotropic viral integration site 2A
chr12_-_53200443 8.89 ENST00000550743.6
integrin subunit beta 7
chr17_+_7336587 8.86 ENST00000575425.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chrX_+_79144664 8.82 ENST00000645147.2
G protein-coupled receptor 174
chr1_+_209756149 8.80 ENST00000367026.7
TRAF3 interacting protein 3
chr19_-_50365625 8.60 ENST00000598915.5
ENST00000253719.7
napsin A aspartic peptidase
chr5_-_39270623 8.55 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr11_-_58578096 8.48 ENST00000528954.5
ENST00000528489.1
leupaxin
chr19_-_51372640 8.46 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chrX_-_71618455 8.38 ENST00000373691.4
ENST00000373693.4
C-X-C motif chemokine receptor 3
chr19_-_35742431 8.11 ENST00000592537.5
ENST00000246532.6
ENST00000588992.5
IGF like family receptor 1
chr14_+_21868822 8.04 ENST00000390436.2
T cell receptor alpha variable 13-1
chr17_+_47733228 8.02 ENST00000177694.2
T-box transcription factor 21
chr1_+_198638968 7.99 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr12_-_68159732 7.90 ENST00000229135.4
interferon gamma
chr20_+_46008900 7.80 ENST00000372330.3
matrix metallopeptidase 9
chr22_+_22818994 7.80 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr16_+_31355165 7.79 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr9_+_73151833 7.78 ENST00000456643.5
ENST00000257497.11
ENST00000415424.5
annexin A1
chr1_+_32251239 7.74 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK proto-oncogene, Src family tyrosine kinase
chr17_-_63699730 7.45 ENST00000578061.5
LIM domain containing 2
chr7_+_18495723 7.34 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
histone deacetylase 9
chr19_-_8502621 7.29 ENST00000600262.1
ENST00000423345.5
PML-RARA regulated adaptor molecule 1
chr8_-_21913671 7.26 ENST00000523932.1
ENST00000276420.9
docking protein 2
chr2_+_90038848 7.23 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr4_-_70666961 7.17 ENST00000510437.5
joining chain of multimeric IgA and IgM
chr4_-_70666884 7.00 ENST00000510614.5
joining chain of multimeric IgA and IgM
chr1_+_168576595 6.94 ENST00000367818.4
X-C motif chemokine ligand 1
chr17_-_63699162 6.93 ENST00000582055.1
LIM domain containing 2
chr19_-_51372686 6.93 ENST00000595217.1
natural killer cell granule protein 7
chr1_+_209768482 6.92 ENST00000367023.5
TRAF3 interacting protein 3
chr11_-_118252279 6.89 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
myelin protein zero like 3
chr14_-_24634266 6.74 ENST00000382540.5
granzyme B
chr12_-_51324091 6.59 ENST00000604560.6
bridging integrator 2
chr3_+_98531965 6.56 ENST00000284311.5
G protein-coupled receptor 15
chr12_-_108632073 6.53 ENST00000228463.6
selectin P ligand
chr8_+_22161788 6.49 ENST00000521315.5
ENST00000437090.6
ENST00000679463.1
ENST00000520605.5
ENST00000522109.5
ENST00000524255.5
ENST00000523296.1
surfactant protein C
chr3_+_111542178 6.40 ENST00000283285.10
ENST00000352690.9
CD96 molecule
chr1_+_17308194 6.32 ENST00000375453.5
ENST00000375448.4
peptidyl arginine deiminase 4
chr4_-_108166750 6.22 ENST00000515500.5
lymphoid enhancer binding factor 1
chr4_-_48114523 6.10 ENST00000506073.1
TXK tyrosine kinase
chr19_-_43780957 6.01 ENST00000648319.1
potassium calcium-activated channel subfamily N member 4
chr12_+_75481204 5.98 ENST00000550491.1
GLI pathogenesis related 1
chr12_-_51324138 5.94 ENST00000452142.7
bridging integrator 2
chr1_-_206921867 5.93 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr3_+_113532508 5.91 ENST00000264852.9
SID1 transmembrane family member 1
chr10_+_17228515 5.88 ENST00000478746.1
vimentin
chr12_-_51324164 5.88 ENST00000615107.6
bridging integrator 2
chr3_-_151329539 5.88 ENST00000325602.6
purinergic receptor P2Y13
chr7_+_18495697 5.84 ENST00000413380.5
ENST00000430454.5
histone deacetylase 9
chr1_+_26545833 5.73 ENST00000531382.5
ribosomal protein S6 kinase A1
chr5_-_139482173 5.70 ENST00000652271.1
stimulator of interferon response cGAMP interactor 1
chr1_-_206921987 5.65 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr13_-_46182136 5.62 ENST00000323076.7
lymphocyte cytosolic protein 1
chr1_-_153375591 5.59 ENST00000368737.5
S100 calcium binding protein A12
chr19_-_14674829 5.46 ENST00000443157.6
ENST00000253673.6
adhesion G protein-coupled receptor E3
chr14_+_21997531 5.44 ENST00000390445.2
T cell receptor alpha variable 17
chr1_+_172659095 5.41 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr11_-_2301859 5.40 ENST00000456145.2
ENST00000381153.8
chromosome 11 open reading frame 21
chr5_-_139482285 5.37 ENST00000652110.1
stimulator of interferon response cGAMP interactor 1
chr4_-_54064586 5.37 ENST00000263921.8
cysteine rich hydrophobic domain 2
chr3_+_111542134 5.32 ENST00000438817.6
CD96 molecule
chr15_+_58138368 5.31 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr11_+_35176611 5.26 ENST00000279452.10
CD44 molecule (Indian blood group)
chr8_-_21913661 5.21 ENST00000518197.1
docking protein 2
chr11_+_35176696 5.17 ENST00000528455.5
CD44 molecule (Indian blood group)
chr1_+_198639162 5.14 ENST00000418674.1
protein tyrosine phosphatase receptor type C
chr17_+_49210699 5.14 ENST00000225941.6
ABI family member 3
chr1_+_159800503 5.11 ENST00000536257.5
ENST00000321935.10
Fc receptor like 6
chr1_-_92486049 5.08 ENST00000427103.5
growth factor independent 1 transcriptional repressor
chr8_+_22161655 5.05 ENST00000318561.7
surfactant protein C
chr19_-_14674886 5.01 ENST00000344373.8
ENST00000595472.1
adhesion G protein-coupled receptor E3
chr5_-_139482341 4.99 ENST00000651699.1
stimulator of interferon response cGAMP interactor 1
chr1_-_153544997 4.96 ENST00000368715.5
S100 calcium binding protein A4
chr4_-_48134200 4.94 ENST00000264316.9
TXK tyrosine kinase
chr11_+_35176639 4.93 ENST00000527889.6
CD44 molecule (Indian blood group)
chr5_-_39202991 4.93 ENST00000515010.5
FYN binding protein 1
chr17_-_36196748 4.87 ENST00000619989.1
C-C motif chemokine ligand 3 like 1
chr1_+_209756101 4.85 ENST00000479796.5
TRAF3 interacting protein 3
chr2_-_174597728 4.82 ENST00000409891.5
ENST00000410117.5
WAS/WASL interacting protein family member 1
chr11_+_35176575 4.82 ENST00000526000.6
CD44 molecule (Indian blood group)
chr15_+_49423233 4.79 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr4_-_108166289 4.76 ENST00000512172.1
lymphoid enhancer binding factor 1
chr8_-_133060347 4.76 ENST00000427060.6
Src like adaptor
chr14_+_75522427 4.74 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chr2_+_30232150 4.72 ENST00000401506.1
ENST00000407930.2
LBH regulator of WNT signaling pathway
chr16_+_85908988 4.67 ENST00000566369.1
interferon regulatory factor 8
chr1_-_206772484 4.65 ENST00000423557.1
interleukin 10
chr8_-_100706763 4.55 ENST00000517990.5
poly(A) binding protein cytoplasmic 1
chr17_+_49210387 4.54 ENST00000419580.6
ABI family member 3
chr2_-_174597795 4.54 ENST00000679041.1
WAS/WASL interacting protein family member 1
chr2_-_174598206 4.53 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr6_+_30061231 4.53 ENST00000376782.6
ENST00000359374.8
ENST00000376785.2
ENST00000332435.10
RNA polymerase I subunit H
chr1_-_161069666 4.50 ENST00000368016.7
Rho GTPase activating protein 30
chr15_+_58138169 4.49 ENST00000558772.5
aquaporin 9
chr8_-_59119121 4.44 ENST00000361421.2
thymocyte selection associated high mobility group box
chr8_-_100706931 4.42 ENST00000520868.5
poly(A) binding protein cytoplasmic 1
chrX_+_47582408 4.39 ENST00000456754.6
ENST00000218388.9
ENST00000377017.5
ENST00000441738.1
TIMP metallopeptidase inhibitor 1
chr1_-_157552455 4.38 ENST00000368190.7
ENST00000368189.3
Fc receptor like 5
chr15_-_55270874 4.34 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr6_+_144583198 4.32 ENST00000367526.8
utrophin
chr9_-_127778659 4.26 ENST00000314830.13
SH2 domain containing 3C
chr3_-_112499457 4.25 ENST00000334529.10
B and T lymphocyte associated
chr11_+_36375978 4.07 ENST00000378867.7
proline rich 5 like
chr11_+_1870871 4.06 ENST00000417766.5
lymphocyte specific protein 1
chr1_-_161069962 4.01 ENST00000368015.1
Rho GTPase activating protein 30
chr10_+_17228215 4.00 ENST00000544301.7
vimentin
chr17_-_49210567 3.97 ENST00000507680.6
G protein subunit gamma transducin 2
chr20_+_56412249 3.97 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chrX_-_136780925 3.96 ENST00000250617.7
Rac/Cdc42 guanine nucleotide exchange factor 6
chr15_+_85555439 3.92 ENST00000558811.2
A-kinase anchoring protein 13
chr6_+_31575557 3.89 ENST00000449264.3
tumor necrosis factor
chr2_+_102418642 3.89 ENST00000264260.6
interleukin 18 receptor accessory protein
chr2_+_227813834 3.77 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr7_-_116030750 3.76 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr6_-_42451261 3.75 ENST00000372917.8
ENST00000340840.6
ENST00000354325.2
transcriptional regulating factor 1
chr11_+_2301987 3.69 ENST00000612299.4
ENST00000182290.9
tetraspanin 32
chr1_+_145719483 3.65 ENST00000369288.7
CD160 molecule
chr5_-_95081482 3.65 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
multiple C2 and transmembrane domain containing 1
chr17_-_48185179 3.64 ENST00000579336.1
src kinase associated phosphoprotein 1
chr8_+_27325516 3.61 ENST00000346049.10
ENST00000420218.3
protein tyrosine kinase 2 beta
chr15_-_55270383 3.60 ENST00000396307.6
RAB27A, member RAS oncogene family
chr12_-_14961559 3.56 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr14_+_21768482 3.54 ENST00000390428.3
T cell receptor alpha variable 6
chr1_+_52633147 3.45 ENST00000517870.2
shisa like 2A
chr22_+_22771791 3.45 ENST00000390313.3
immunoglobulin lambda variable 3-12
chr1_-_161069857 3.38 ENST00000368013.8
Rho GTPase activating protein 30
chr3_+_50088912 3.34 ENST00000469838.5
ENST00000404526.6
ENST00000347869.8
ENST00000441305.5
RNA binding motif protein 5
chr1_-_157552470 3.32 ENST00000361835.8
Fc receptor like 5
chr1_+_111229692 3.30 ENST00000466741.5
ENST00000477185.6
chitinase 3 like 2
chr11_+_121576760 3.29 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr15_-_55270280 3.28 ENST00000564609.5
RAB27A, member RAS oncogene family
chr16_+_28494634 3.10 ENST00000564831.6
ENST00000431282.2
apolipoprotein B receptor
chr1_+_111229753 3.08 ENST00000467038.6
ENST00000497587.6
chitinase 3 like 2
chr7_-_116030735 3.06 ENST00000393485.5
transcription factor EC
chr19_+_10836575 3.05 ENST00000592854.5
chromosome 19 open reading frame 38
chr5_-_111756245 3.03 ENST00000447165.6
neuronal regeneration related protein
chr14_+_75522531 3.00 ENST00000555504.1
basic leucine zipper ATF-like transcription factor
chr8_+_27311471 2.96 ENST00000397501.5
protein tyrosine kinase 2 beta
chr16_+_72054477 2.94 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr9_-_127755243 2.94 ENST00000629203.2
ENST00000420366.5
SH2 domain containing 3C
chr6_-_111759910 2.93 ENST00000517419.5
FYN proto-oncogene, Src family tyrosine kinase
chr15_-_60402873 2.90 ENST00000557904.5
annexin A2
chr16_+_88382950 2.88 ENST00000565624.3
zinc finger protein 469
chr19_-_43781249 2.87 ENST00000615047.4
potassium calcium-activated channel subfamily N member 4
chr3_-_112499358 2.86 ENST00000383680.4
B and T lymphocyte associated
chr13_-_28100556 2.80 ENST00000241453.12
fms related receptor tyrosine kinase 3
chr19_+_47309853 2.79 ENST00000355085.4
complement C5a receptor 1
chr5_-_95081858 2.76 ENST00000505465.1
multiple C2 and transmembrane domain containing 1
chr22_-_30246739 2.73 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr3_-_146528750 2.73 ENST00000483300.5
phospholipid scramblase 1
chr11_+_2302119 2.73 ENST00000381121.7
tetraspanin 32
chr6_+_158649997 2.70 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
synaptotagmin like 3
chr5_+_148826600 2.68 ENST00000305988.6
adrenoceptor beta 2
chr17_-_75844533 2.67 ENST00000586108.1
unc-13 homolog D
chr12_-_14961256 2.65 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr16_+_29663219 2.64 ENST00000436527.5
ENST00000360121.4
ENST00000652691.1
ENST00000449759.2
sialophorin
quinolinate phosphoribosyltransferase
chr10_+_8045345 2.61 ENST00000643001.1
GATA binding protein 3
chr1_+_117001744 2.61 ENST00000256652.8
ENST00000682167.1
ENST00000369470.1
CD101 molecule
chr1_-_173205543 2.51 ENST00000367718.5
TNF superfamily member 4
chr9_-_115091018 2.49 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
tenascin C
chr19_+_10086787 2.49 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr15_+_80933358 2.48 ENST00000560027.1
cell migration inducing hyaluronidase 1
chr1_+_111229813 2.48 ENST00000524472.5
chitinase 3 like 2
chr11_-_65780917 2.45 ENST00000532090.3
adaptor related protein complex 5 subunit beta 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX3_BCL11A

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 28.9 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
5.2 20.7 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
4.8 4.8 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
4.5 13.6 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
4.2 20.9 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
3.9 11.7 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
3.9 15.6 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
3.5 6.9 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
3.4 10.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
3.2 9.6 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
2.9 20.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
2.6 34.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
2.6 7.8 GO:0036292 DNA rewinding(GO:0036292)
2.3 11.3 GO:2000503 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
2.2 24.0 GO:0002051 osteoblast fate commitment(GO:0002051)
2.1 16.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
2.0 17.9 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
2.0 9.8 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
1.9 3.9 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.9 13.3 GO:0043316 cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
1.8 8.9 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.7 5.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.7 28.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.6 11.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
1.6 11.0 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.4 20.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.4 4.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.3 6.6 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
1.3 6.5 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.3 20.7 GO:0001865 NK T cell differentiation(GO:0001865)
1.3 9.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.3 14.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.3 19.0 GO:0032074 regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074)
1.3 6.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.2 29.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.1 3.3 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.1 5.4 GO:0048388 endosomal lumen acidification(GO:0048388)
1.0 6.2 GO:0071461 cellular response to redox state(GO:0071461)
1.0 2.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.0 7.8 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.9 3.8 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.9 8.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.9 2.8 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.9 2.7 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.9 2.7 GO:0002432 granuloma formation(GO:0002432)
0.8 10.9 GO:0043129 surfactant homeostasis(GO:0043129)
0.8 2.5 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.8 17.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.8 2.3 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.8 3.1 GO:1901074 cellular response to interleukin-13(GO:0035963) regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.8 16.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.7 4.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.7 2.9 GO:0052417 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.7 3.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.7 2.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.7 2.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.7 19.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.7 2.6 GO:2000734 regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734)
0.6 9.0 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.6 4.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.6 1.8 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.6 5.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.6 7.3 GO:1902563 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.5 9.9 GO:0070307 lens fiber cell development(GO:0070307)
0.5 8.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.5 4.7 GO:2000035 regulation of stem cell division(GO:2000035)
0.5 8.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.5 15.0 GO:0001562 response to protozoan(GO:0001562)
0.5 1.5 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.5 2.5 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.5 1.5 GO:0070377 negative regulation of ERK5 cascade(GO:0070377)
0.5 2.4 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.5 1.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.5 2.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.5 24.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.5 10.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.4 1.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.4 3.9 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.4 1.7 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.4 1.3 GO:0060690 positive regulation of vascular wound healing(GO:0035470) epithelial cell differentiation involved in salivary gland development(GO:0060690) epithelial cell maturation involved in salivary gland development(GO:0060691) regulation of plasma cell differentiation(GO:1900098) positive regulation of plasma cell differentiation(GO:1900100) positive regulation of lactation(GO:1903489)
0.4 1.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.4 1.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 20.2 GO:0071800 podosome assembly(GO:0071800)
0.4 0.8 GO:1905237 response to cyclosporin A(GO:1905237)
0.4 10.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.4 5.9 GO:0033227 dsRNA transport(GO:0033227)
0.4 1.8 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.4 2.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) common myeloid progenitor cell proliferation(GO:0035726)
0.3 1.7 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.3 1.0 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.3 2.0 GO:0071104 response to interleukin-9(GO:0071104)
0.3 1.3 GO:0032599 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.3 2.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 5.8 GO:0038203 TORC2 signaling(GO:0038203)
0.3 4.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 33.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 10.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 2.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 2.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.4 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.2 0.7 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 0.9 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.2 6.6 GO:0072678 T cell migration(GO:0072678)
0.2 21.5 GO:0006968 cellular defense response(GO:0006968)
0.2 2.0 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 2.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 3.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.2 4.0 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 2.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 1.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.6 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.2 0.6 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 1.7 GO:0007172 signal complex assembly(GO:0007172)
0.2 3.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.2 1.2 GO:0003383 apical constriction(GO:0003383)
0.2 8.1 GO:0043029 T cell homeostasis(GO:0043029)
0.2 32.9 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.2 1.0 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 1.5 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 1.0 GO:1905232 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) cellular response to L-glutamate(GO:1905232) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 1.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.2 4.7 GO:0016180 snRNA processing(GO:0016180)
0.2 2.4 GO:0043383 negative T cell selection(GO:0043383)
0.1 2.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.9 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.0 GO:0043144 snoRNA processing(GO:0043144)
0.1 1.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 1.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 3.7 GO:0090656 t-circle formation(GO:0090656)
0.1 5.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 3.1 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 3.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 7.7 GO:0031295 T cell costimulation(GO:0031295)
0.1 2.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 2.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.5 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 1.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 1.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 7.8 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 2.4 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 0.4 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 2.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.8 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 4.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 8.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.7 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.6 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0043320 natural killer cell degranulation(GO:0043320)
0.1 1.3 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 1.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 5.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.8 GO:1903800 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 1.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.5 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 1.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 1.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 4.0 GO:0007602 phototransduction(GO:0007602)
0.0 1.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 2.0 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 1.8 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.5 GO:0098909 maintenance of centrosome location(GO:0051661) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.5 GO:0035878 ectodermal cell differentiation(GO:0010668) nail development(GO:0035878)
0.0 7.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 38.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 3.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.5 GO:1901256 interleukin-21 production(GO:0032625) macrophage colony-stimulating factor production(GO:0036301) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0 0.5 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 1.0 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 2.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0048484 enteric nervous system development(GO:0048484)
0.0 5.1 GO:0007286 spermatid development(GO:0007286)
0.0 1.3 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 5.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 2.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 3.9 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 11.1 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.0 0.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.6 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 14.2 GO:0071757 hexameric IgM immunoglobulin complex(GO:0071757)
1.8 8.9 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.7 20.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.5 21.5 GO:0097486 multivesicular body lumen(GO:0097486)
1.1 7.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.1 21.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.0 34.8 GO:0042101 T cell receptor complex(GO:0042101)
0.8 4.2 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.8 15.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.7 2.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.7 2.9 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.7 27.9 GO:0001891 phagocytic cup(GO:0001891)
0.7 13.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.7 44.7 GO:0001772 immunological synapse(GO:0001772)
0.4 9.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 14.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.3 36.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 6.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 7.6 GO:0031932 TORC2 complex(GO:0031932)
0.3 67.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 9.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 6.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 3.4 GO:0032039 integrator complex(GO:0032039)
0.2 10.8 GO:0008305 integrin complex(GO:0008305)
0.2 4.3 GO:0070938 contractile ring(GO:0070938)
0.2 23.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.2 3.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.3 GO:1990037 Lewy body core(GO:1990037)
0.2 3.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 63.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.3 GO:0001939 female pronucleus(GO:0001939)
0.1 0.5 GO:0044307 dendritic branch(GO:0044307)
0.1 1.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 12.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 25.4 GO:0005884 actin filament(GO:0005884)
0.1 1.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 8.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 4.4 GO:0071565 nBAF complex(GO:0071565)
0.1 1.3 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.1 9.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 0.9 GO:0044754 autolysosome(GO:0044754)
0.1 2.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 37.9 GO:0000790 nuclear chromatin(GO:0000790)
0.1 3.1 GO:0002102 podosome(GO:0002102)
0.1 1.8 GO:0005686 U2 snRNP(GO:0005686)
0.1 5.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 12.3 GO:0016605 PML body(GO:0016605)
0.1 7.4 GO:0043235 receptor complex(GO:0043235)
0.1 6.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 10.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 6.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 5.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.1 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 3.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 2.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 8.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 4.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 2.2 GO:1990391 DNA repair complex(GO:1990391)
0.0 4.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.7 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.0 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 14.8 GO:0005769 early endosome(GO:0005769)
0.0 1.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 4.4 GO:0034774 secretory granule lumen(GO:0034774)
0.0 4.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 1.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 27.5 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
3.5 31.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
2.8 11.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
2.0 14.2 GO:0019862 IgA binding(GO:0019862)
2.0 9.8 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
1.3 10.7 GO:0042610 CD8 receptor binding(GO:0042610)
1.3 6.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.3 20.3 GO:0030284 estrogen receptor activity(GO:0030284)
1.3 6.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.2 9.9 GO:1990254 keratin filament binding(GO:1990254)
1.2 10.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.2 29.9 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
1.0 3.1 GO:0005139 interleukin-7 receptor binding(GO:0005139)
0.9 3.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.9 2.8 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.9 12.8 GO:0051525 NFAT protein binding(GO:0051525)
0.9 2.7 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.8 8.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 2.3 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.8 3.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.7 5.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 3.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.7 2.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.6 6.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6 13.9 GO:0005522 profilin binding(GO:0005522)
0.6 13.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.6 23.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.6 61.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.5 8.9 GO:0004568 chitinase activity(GO:0004568)
0.5 7.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.5 8.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 22.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 16.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.5 10.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.4 2.9 GO:0030492 hemoglobin binding(GO:0030492)
0.4 13.3 GO:0031489 myosin V binding(GO:0031489)
0.4 3.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.4 10.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 15.6 GO:0043274 phospholipase binding(GO:0043274)
0.4 1.4 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.3 10.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 2.6 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3 9.0 GO:0008494 translation activator activity(GO:0008494)
0.3 2.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.3 15.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 1.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 2.5 GO:0045545 syndecan binding(GO:0045545)
0.3 8.8 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.3 2.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 3.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 20.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 1.4 GO:0050436 microfibril binding(GO:0050436)
0.2 1.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 7.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 1.0 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.2 0.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 2.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.9 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 2.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.9 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 7.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.5 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.2 4.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 59.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 3.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 3.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 3.8 GO:0008301 DNA binding, bending(GO:0008301)
0.2 0.8 GO:0035500 MH2 domain binding(GO:0035500)
0.1 2.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 2.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 4.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.7 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 5.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 20.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.4 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.1 15.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 3.5 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.7 GO:0070878 primary miRNA binding(GO:0070878)
0.1 2.8 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.4 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 3.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 4.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 3.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 44.1 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 12.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.8 GO:0036310 annealing helicase activity(GO:0036310)
0.1 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.3 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 9.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 23.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 4.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.9 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 2.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.9 GO:0019843 rRNA binding(GO:0019843)
0.0 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 10.1 GO:0005543 phospholipid binding(GO:0005543)
0.0 2.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 5.1 GO:0051020 GTPase binding(GO:0051020)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 23.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.7 8.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.7 83.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.6 24.8 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.5 36.1 PID BCR 5PATHWAY BCR signaling pathway
0.5 42.1 PID ARF6 PATHWAY Arf6 signaling events
0.5 53.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.4 12.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 7.1 PID IL27 PATHWAY IL27-mediated signaling events
0.3 17.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.3 12.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.3 13.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 20.8 PID FGF PATHWAY FGF signaling pathway
0.2 35.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 9.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 18.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 13.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 2.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 8.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 6.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 17.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 4.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 7.7 PID AURORA B PATHWAY Aurora B signaling
0.1 9.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 8.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 23.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 30.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.2 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.8 PID ATR PATHWAY ATR signaling pathway
0.1 6.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 4.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 3.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 13.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.2 67.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.8 20.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 22.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.6 46.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.6 9.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 25.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 13.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 12.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 7.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 14.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 36.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 9.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 17.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 5.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 7.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 6.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 2.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 5.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 9.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 16.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 7.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 12.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 13.5 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 3.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 7.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 2.7 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 4.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 10.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 20.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 14.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 4.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 7.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 8.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 7.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines