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Illumina Body Map 2 (GSE30611)

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Results for RXRA_NR2F6_NR2C2

Z-value: 1.30

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Transcription factors associated with RXRA_NR2F6_NR2C2

Gene Symbol Gene ID Gene Info
ENSG00000186350.12 retinoid X receptor alpha
ENSG00000160113.6 nuclear receptor subfamily 2 group F member 6
ENSG00000177463.15 nuclear receptor subfamily 2 group C member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2C2hg38_v1_chr3_+_15003912_15003941-0.648.6e-05Click!
RXRAhg38_v1_chr9_+_134326435_1343264940.467.4e-03Click!
NR2F6hg38_v1_chr19_-_17245889_172459540.421.8e-02Click!

Activity profile of RXRA_NR2F6_NR2C2 motif

Sorted Z-values of RXRA_NR2F6_NR2C2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_4153616 6.37 ENST00000078445.7
ENST00000595923.5
ENST00000602257.5
ENST00000602147.1
cAMP responsive element binding protein 3 like 3
chr1_-_161223559 6.27 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
apolipoprotein A2
chr10_-_95069489 5.63 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chr17_+_1742836 4.93 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
serpin family F member 2
chr1_-_230714112 4.77 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
angiotensinogen
chr1_-_161223408 4.53 ENST00000491350.1
apolipoprotein A2
chr1_-_11047225 4.46 ENST00000400898.3
ENST00000400897.8
mannan binding lectin serine peptidase 2
chrX_+_139530730 4.15 ENST00000218099.7
coagulation factor IX
chr3_+_46497970 4.14 ENST00000296142.4
receptor transporter protein 3
chr1_-_173917281 3.90 ENST00000367698.4
serpin family C member 1
chr11_-_116823293 3.87 ENST00000357780.5
apolipoprotein A4
chr13_+_113105782 3.82 ENST00000541084.5
ENST00000346342.8
ENST00000375581.3
coagulation factor VII
chrX_+_139530752 3.68 ENST00000394090.2
coagulation factor IX
chr17_+_29043124 3.46 ENST00000323372.9
pipecolic acid and sarcosine oxidase
chr1_-_146021724 3.33 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
hemojuvelin BMP co-receptor
chr12_-_7018465 3.17 ENST00000261407.9
lysophosphatidylcholine acyltransferase 3
chrX_-_54994022 3.09 ENST00000614686.1
ENST00000374992.6
ENST00000375006.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr4_+_158672266 3.08 ENST00000684622.1
ENST00000683483.1
ENST00000684641.1
ENST00000682456.1
ENST00000684627.1
ENST00000511912.6
ENST00000684505.1
ENST00000683305.1
ENST00000684036.1
ENST00000683751.1
ENST00000684129.1
ENST00000307738.5
electron transfer flavoprotein dehydrogenase
chr6_+_31655888 2.97 ENST00000375916.4
apolipoprotein M
chr11_+_116829898 2.96 ENST00000227667.8
ENST00000375345.3
apolipoprotein C3
chr17_-_36001549 2.90 ENST00000617897.2
C-C motif chemokine ligand 15
chr22_+_50705495 2.65 ENST00000664402.1
SH3 and multiple ankyrin repeat domains 3
chr11_-_116837586 2.65 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
apolipoprotein A1
chr10_-_72954790 2.65 ENST00000373032.4
phospholipase A2 group XIIB
chr19_-_48363914 2.64 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chr19_+_35282520 2.56 ENST00000222304.5
hepcidin antimicrobial peptide
chr18_-_49813869 2.52 ENST00000586485.5
ENST00000587994.5
ENST00000586100.1
acetyl-CoA acyltransferase 2
chr5_-_42811884 2.52 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chrX_+_38352573 2.51 ENST00000039007.5
ornithine transcarbamylase
chr19_-_48364034 2.43 ENST00000435956.7
transmembrane protein 143
chr4_+_158672237 2.39 ENST00000682734.1
electron transfer flavoprotein dehydrogenase
chr18_-_49813512 2.34 ENST00000285093.15
acetyl-CoA acyltransferase 2
chr14_+_94619313 2.32 ENST00000621603.1
serpin family A member 3
chr20_+_57561103 2.29 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr19_-_17245889 2.23 ENST00000291442.4
nuclear receptor subfamily 2 group F member 6
chr17_-_36017953 2.21 ENST00000612516.4
ENST00000615050.2
C-C motif chemokine ligand 23
chr17_+_7630094 2.21 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
sex hormone binding globulin
chr17_+_4950147 2.18 ENST00000522301.5
enolase 3
chr9_-_101384999 2.17 ENST00000259407.7
bile acid-CoA:amino acid N-acyltransferase
chr3_-_52826834 2.16 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chr20_+_38033719 2.14 ENST00000373433.9
regulation of nuclear pre-mRNA domain containing 1B
chr3_-_48898813 2.04 ENST00000319017.5
ENST00000430379.5
solute carrier family 25 member 20
chr5_+_42548043 2.02 ENST00000618088.4
ENST00000612382.4
growth hormone receptor
chr22_-_42130800 2.00 ENST00000645361.2
ENST00000359033.4
cytochrome P450 family 2 subfamily D member 6
chr8_-_17697654 1.99 ENST00000297488.10
microtubule associated scaffold protein 1
chr17_+_7627963 1.98 ENST00000575729.5
ENST00000340624.9
sex hormone binding globulin
chr1_-_169586539 1.98 ENST00000367796.3
coagulation factor V
chr7_+_98211431 1.92 ENST00000609256.2
basic helix-loop-helix family member a15
chrX_+_2828808 1.89 ENST00000381163.7
glycogenin 2
chrX_+_2828921 1.88 ENST00000398806.8
glycogenin 2
chr6_+_43298254 1.87 ENST00000372585.10
ENST00000449231.5
ENST00000372589.7
solute carrier family 22 member 7
chr17_+_7219857 1.87 ENST00000583312.5
ENST00000350303.9
ENST00000584103.5
ENST00000356839.10
ENST00000579886.2
acyl-CoA dehydrogenase very long chain
chr6_+_31927683 1.86 ENST00000456570.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr3_+_186613052 1.83 ENST00000411641.7
ENST00000273784.5
alpha 2-HS glycoprotein
chr1_-_169586471 1.80 ENST00000367797.9
coagulation factor V
chr17_+_1771688 1.79 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr5_+_36166556 1.77 ENST00000677886.1
S-phase kinase associated protein 2
chr10_-_52771700 1.69 ENST00000373968.3
mannose binding lectin 2
chr1_-_145707387 1.69 ENST00000451928.6
PDZ domain containing 1
chr6_+_31948956 1.67 ENST00000483004.1
complement factor B
chr1_-_145707345 1.64 ENST00000417171.6
PDZ domain containing 1
chr12_+_109139397 1.63 ENST00000377854.9
ENST00000377848.7
acetyl-CoA carboxylase beta
chr6_+_31927703 1.62 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr7_-_15561986 1.55 ENST00000342526.8
alkylglycerol monooxygenase
chr19_-_38812936 1.54 ENST00000307751.9
ENST00000594209.1
galectin 4
chr13_+_113122791 1.53 ENST00000375559.8
ENST00000409306.5
ENST00000375551.7
coagulation factor X
chr19_+_44891206 1.53 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
translocase of outer mitochondrial membrane 40
chr9_-_33402449 1.50 ENST00000377425.8
aquaporin 7
chr16_-_4351283 1.50 ENST00000318059.8
presequence translocase associated motor 16
chrX_+_129738942 1.48 ENST00000371106.4
X-prolyl aminopeptidase 2
chr13_+_100089015 1.48 ENST00000376286.8
ENST00000376279.7
ENST00000376285.6
propionyl-CoA carboxylase subunit alpha
chr6_+_43298326 1.47 ENST00000372574.7
solute carrier family 22 member 7
chr6_+_31927486 1.45 ENST00000442278.6
complement C2
chr3_+_186666003 1.45 ENST00000232003.5
histidine rich glycoprotein
chr22_-_42144549 1.44 ENST00000614967.4
ENST00000612115.1
cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
chr17_-_2711633 1.44 ENST00000435359.5
clustered mitochondria homolog
chr10_+_94683722 1.43 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr9_-_33402551 1.41 ENST00000297988.6
ENST00000624075.3
ENST00000625032.1
ENST00000625109.3
aquaporin 7
chr2_+_27496830 1.41 ENST00000264717.7
glucokinase regulator
chr7_-_75994574 1.38 ENST00000439537.5
ENST00000493111.7
ENST00000417509.5
ENST00000485200.1
transmembrane protein 120A
chr1_-_155301423 1.37 ENST00000342741.6
pyruvate kinase L/R
chr11_-_624924 1.37 ENST00000358353.8
ENST00000397542.7
ENST00000526077.5
ENST00000534311.1
ENST00000531088.5
cadherin related family member 5
chr17_-_2711736 1.37 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr16_-_10559135 1.34 ENST00000536829.1
epithelial membrane protein 2
chr9_+_112380080 1.34 ENST00000398803.1
ENST00000398805.8
hydroxysteroid dehydrogenase like 2
chr1_-_119768892 1.34 ENST00000369406.8
ENST00000544913.2
3-hydroxy-3-methylglutaryl-CoA synthase 2
chr9_+_136945234 1.30 ENST00000371634.7
complement C8 gamma chain
chr19_-_35812838 1.30 ENST00000653904.2
proline dehydrogenase 2
chr2_+_199955770 1.29 ENST00000435773.2
matrix AAA peptidase interacting protein 1
chr19_-_6720641 1.29 ENST00000245907.11
complement C3
chr3_+_186842687 1.26 ENST00000444204.2
ENST00000320741.7
adiponectin, C1Q and collagen domain containing
chr2_-_74440484 1.26 ENST00000305557.9
ENST00000233330.6
rhotekin
chr6_+_31927510 1.26 ENST00000447952.6
complement C2
chr6_+_130827398 1.25 ENST00000541421.2
small leucine rich protein 1
chr10_+_94683771 1.24 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr1_-_155300979 1.23 ENST00000392414.7
pyruvate kinase L/R
chr11_+_47257953 1.23 ENST00000437276.1
ENST00000436029.5
ENST00000467728.5
ENST00000441012.7
ENST00000405853.7
nuclear receptor subfamily 1 group H member 3
chr19_+_43596480 1.22 ENST00000533118.5
zinc finger protein 576
chr17_-_1710368 1.22 ENST00000330676.8
TLC domain containing 2
chr3_-_42875871 1.22 ENST00000316161.6
ENST00000437102.1
cytochrome P450 family 8 subfamily B member 1
chr6_+_125154189 1.20 ENST00000532429.5
ENST00000534199.5
TPD52 like 1
chr11_-_66907891 1.19 ENST00000393955.6
pyruvate carboxylase
chr10_+_99782628 1.19 ENST00000648689.1
ENST00000647814.1
ATP binding cassette subfamily C member 2
chr16_-_4351257 1.18 ENST00000577031.5
presequence translocase associated motor 16
chr19_-_51366338 1.18 ENST00000596253.1
ENST00000309244.9
electron transfer flavoprotein subunit beta
chr1_+_61082553 1.17 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr16_+_56961942 1.16 ENST00000200676.8
ENST00000566128.1
cholesteryl ester transfer protein
chr22_+_24952705 1.16 ENST00000358431.8
KIAA1671
chr1_+_65148169 1.15 ENST00000327299.8
adenylate kinase 4
chr1_+_65147830 1.13 ENST00000395334.6
adenylate kinase 4
chr18_-_74291924 1.13 ENST00000494131.6
ENST00000340533.9
ENST00000397914.4
cytochrome b5 type A
chr20_+_62302093 1.13 ENST00000491935.5
adhesion regulating molecule 1
chr1_-_197067234 1.11 ENST00000367412.2
coagulation factor XIII B chain
chr12_+_120725796 1.10 ENST00000242592.9
ENST00000411593.2
acyl-CoA dehydrogenase short chain
chr3_-_58537283 1.09 ENST00000459701.6
acyl-CoA oxidase 2
chr2_-_31414694 1.09 ENST00000379416.4
xanthine dehydrogenase
chr3_-_58537181 1.09 ENST00000302819.10
acyl-CoA oxidase 2
chr22_-_19178402 1.08 ENST00000451283.5
solute carrier family 25 member 1
chr11_+_64306227 1.08 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr11_+_22666604 1.07 ENST00000454584.6
growth arrest specific 2
chr17_+_4788926 1.05 ENST00000331264.8
glycolipid transfer protein domain containing 2
chr2_+_233712905 1.05 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr1_+_65147514 1.05 ENST00000545314.5
adenylate kinase 4
chr11_+_47257658 1.04 ENST00000412937.5
ENST00000449369.5
nuclear receptor subfamily 1 group H member 3
chrX_+_38561530 1.03 ENST00000378482.7
ENST00000286824.6
tetraspanin 7
chr3_+_52198086 1.02 ENST00000469224.5
ENST00000394965.6
5'-aminolevulinate synthase 1
chr19_+_35139440 1.01 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chr9_-_16705062 1.01 ENST00000471301.3
basonuclin 2
chr11_+_47257604 1.00 ENST00000444396.5
ENST00000457932.5
nuclear receptor subfamily 1 group H member 3
chr3_-_119677346 1.00 ENST00000484810.5
ENST00000497116.1
ENST00000261070.7
cytochrome c oxidase copper chaperone COX17
chr2_-_169031317 1.00 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr3_+_52198113 0.98 ENST00000310271.6
5'-aminolevulinate synthase 1
chr3_+_52198152 0.98 ENST00000484952.6
5'-aminolevulinate synthase 1
chr12_+_131929194 0.97 ENST00000443358.6
pseudouridine synthase 1
chr11_-_61581104 0.96 ENST00000263846.8
synaptotagmin 7
chr4_-_108762964 0.96 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ethanolamine-phosphate phospho-lyase
chr9_+_72149424 0.95 ENST00000358399.8
ENST00000376986.5
guanine deaminase
chr8_+_22367259 0.94 ENST00000520644.1
ENST00000359741.10
ENST00000381237.6
ENST00000240095.10
solute carrier family 39 member 14
chr2_+_218419114 0.94 ENST00000454069.5
ENST00000392114.6
ENST00000248444.10
villin 1
chr7_-_75073774 0.94 ENST00000610322.5
RCC1 like
chr14_-_69797232 0.94 ENST00000216540.5
solute carrier family 10 member 1
chr17_-_7627803 0.94 ENST00000573566.1
ENST00000269298.10
spermidine/spermine N1-acetyltransferase family member 2
chr6_+_32038382 0.93 ENST00000478281.5
ENST00000471671.4
ENST00000435122.3
ENST00000644719.2
cytochrome P450 family 21 subfamily A member 2
chr19_+_35138993 0.93 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr6_+_43770202 0.93 ENST00000372067.8
ENST00000672860.2
vascular endothelial growth factor A
chr6_+_80106623 0.92 ENST00000369760.8
ENST00000356489.9
branched chain keto acid dehydrogenase E1 subunit beta
chr19_+_18193192 0.92 ENST00000599612.3
MPV17 mitochondrial inner membrane protein like 2
chr22_-_37109703 0.90 ENST00000406856.7
ENST00000676104.1
transmembrane serine protease 6
chr17_-_29176752 0.89 ENST00000533112.5
myosin XVIIIA
chr11_-_61580826 0.89 ENST00000540677.5
ENST00000542836.5
ENST00000542670.5
ENST00000535826.5
ENST00000545053.1
ENST00000539008.6
synaptotagmin 7
chr19_+_35139724 0.89 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr14_-_75176593 0.88 ENST00000303575.9
transmembrane p24 trafficking protein 10
chr1_-_154974361 0.87 ENST00000368453.8
ENST00000368450.5
SHC adaptor protein 1
chr3_-_197573323 0.87 ENST00000358186.6
ENST00000431056.5
3-hydroxybutyrate dehydrogenase 1
chr8_-_144326842 0.85 ENST00000528718.6
diacylglycerol O-acyltransferase 1
chr7_-_75073844 0.85 ENST00000614461.4
ENST00000618035.4
RCC1 like
chr11_-_1757452 0.84 ENST00000427721.3
novel protein
chr12_+_57454674 0.82 ENST00000547970.1
inhibin subunit beta E
chr12_+_100503352 0.82 ENST00000551379.5
ENST00000188403.7
nuclear receptor subfamily 1 group H member 4
chr20_+_44355692 0.82 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr3_-_9880250 0.81 ENST00000423850.5
ENST00000336832.7
ENST00000675828.1
ENST00000618572.4
ENST00000455015.6
cell death inducing DFFA like effector c
chr1_+_156114251 0.81 ENST00000361308.9
lamin A/C
chr8_+_22367526 0.80 ENST00000289952.9
ENST00000524285.1
solute carrier family 39 member 14
chr11_+_62771357 0.80 ENST00000526261.1
ENST00000294168.8
TATA-box binding protein associated factor 6 like
chr19_-_38315749 0.80 ENST00000589247.1
ENST00000329420.12
ENST00000591784.5
Yip1 interacting factor homolog B, membrane trafficking protein
chr19_-_33521749 0.79 ENST00000588328.6
ENST00000651901.1
ENST00000651646.1
ENST00000436370.7
ENST00000244137.12
ENST00000397032.8
peptidase D
chr20_+_45881218 0.79 ENST00000372523.1
zinc finger SWIM-type containing 1
chr14_+_104745960 0.78 ENST00000556623.1
ENST00000555674.1
adenylosuccinate synthase 1
chrX_-_15493234 0.78 ENST00000380420.10
pirin
chr2_-_197499826 0.78 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
heat shock protein family D (Hsp60) member 1
chr19_-_42423100 0.78 ENST00000597001.1
lipase E, hormone sensitive type
chr3_+_58237501 0.77 ENST00000295962.8
abhydrolase domain containing 6, acylglycerol lipase
chr9_+_72149351 0.77 ENST00000238018.8
guanine deaminase
chr1_+_15617415 0.77 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr14_+_77320996 0.76 ENST00000361389.8
ENST00000554279.5
ENST00000557639.5
ENST00000349555.7
ENST00000216465.10
ENST00000556627.5
ENST00000557053.5
glutathione S-transferase zeta 1
chr22_+_24952730 0.76 ENST00000406486.8
KIAA1671
chr16_+_4425805 0.76 ENST00000431375.6
ENST00000355296.8
ENST00000262375.11
ENST00000574895.1
DnaJ heat shock protein family (Hsp40) member A3
chr11_+_64305497 0.75 ENST00000406310.6
ENST00000677967.1
ENST00000000442.11
estrogen related receptor alpha
chr11_-_61891381 0.74 ENST00000525588.5
fatty acid desaturase 3
chr5_+_172834225 0.73 ENST00000393784.8
endoplasmic reticulum-golgi intermediate compartment 1
chr22_+_19758749 0.73 ENST00000680333.1
T-box transcription factor 1
chr19_+_35138778 0.72 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr22_+_37024137 0.72 ENST00000628507.1
mercaptopyruvate sulfurtransferase
chr22_+_46267997 0.72 ENST00000421359.5
ENST00000381031.8
ENST00000629918.1
tetratricopeptide repeat domain 38
chr19_-_38315900 0.71 ENST00000592694.5
Yip1 interacting factor homolog B, membrane trafficking protein
chr19_-_1021114 0.70 ENST00000333175.9
ENST00000356663.8
transmembrane protein 259
chr1_+_153775357 0.70 ENST00000624995.4
solute carrier family 27 member 3
chr6_-_87589961 0.69 ENST00000369536.10
arginyl-tRNA synthetase 2, mitochondrial
chr12_+_131929259 0.67 ENST00000542167.2
ENST00000376649.8
ENST00000538037.5
ENST00000456665.6
pseudouridine synthase 1
chr1_-_155187272 0.67 ENST00000473363.3
novel protein
chr2_-_74529670 0.66 ENST00000377526.4
AUP1 lipid droplet regulating VLDL assembly factor
chrX_+_153494970 0.65 ENST00000331595.9
ENST00000431891.1
biglycan
chr7_-_65982205 0.64 ENST00000421103.5
ENST00000304895.9
glucuronidase beta
chr1_-_93180261 0.64 ENST00000370280.1
ENST00000479918.5
transmembrane p24 trafficking protein 5
chr2_-_27890348 0.63 ENST00000302188.8
ribokinase
chr4_+_139665768 0.63 ENST00000616265.4
ENST00000265498.6
ENST00000506797.5
microsomal glutathione S-transferase 2
chr2_-_197499857 0.63 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
heat shock protein family D (Hsp60) member 1
chr11_-_61891534 0.62 ENST00000278829.7
fatty acid desaturase 3
chr19_+_43596575 0.62 ENST00000528387.5
ENST00000529930.1
ENST00000336564.5
ENST00000607544.1
zinc finger protein 576
serine/arginine repetitive matrix 5
chr1_-_155300933 0.62 ENST00000434082.3
pyruvate kinase L/R

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRA_NR2F6_NR2C2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.8 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
2.7 2.7 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
2.0 2.0 GO:0009822 alkaloid catabolic process(GO:0009822)
1.7 6.8 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
1.6 4.8 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
1.3 13.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.9 2.6 GO:1990641 response to iron ion starvation(GO:1990641)
0.8 2.5 GO:0097272 ammonia homeostasis(GO:0097272)
0.8 5.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.8 2.3 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.8 3.8 GO:0032571 response to vitamin K(GO:0032571)
0.7 4.9 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.7 2.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.7 2.0 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.7 3.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.6 1.9 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.6 4.9 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.6 3.5 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.6 1.7 GO:0006147 guanine catabolic process(GO:0006147)
0.5 3.6 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.5 1.0 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.5 1.4 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.5 1.4 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.5 11.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.5 1.4 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.4 2.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.4 3.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.4 1.3 GO:0001970 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of activation of membrane attack complex(GO:0001970) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.4 1.3 GO:2000584 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.4 1.2 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.4 1.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 1.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.3 6.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.3 1.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 5.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 0.9 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 4.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 0.9 GO:1903572 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3 0.9 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.3 4.2 GO:0019530 taurine metabolic process(GO:0019530)
0.3 1.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 1.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.3 1.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 4.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.3 3.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.3 2.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 2.9 GO:0015793 glycerol transport(GO:0015793)
0.3 1.8 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 5.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 3.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 0.7 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 1.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 0.9 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 0.6 GO:0019303 D-ribose catabolic process(GO:0019303)
0.2 1.0 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.2 0.6 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 1.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 1.2 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.6 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 0.8 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 0.9 GO:1902896 cytoplasmic actin-based contraction involved in cell motility(GO:0060327) terminal web assembly(GO:1902896)
0.2 0.9 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 2.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.9 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 3.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 0.5 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.2 1.3 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.2 2.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 1.4 GO:0033131 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.1 3.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 3.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.4 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
0.1 0.7 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 2.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.9 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.5 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 2.0 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 1.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 3.2 GO:0015879 carnitine transport(GO:0015879)
0.1 1.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 1.3 GO:0070836 caveola assembly(GO:0070836)
0.1 1.0 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.3 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 4.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.9 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 3.2 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.4 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 2.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.6 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.8 GO:2000124 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 6.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.2 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.3 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 1.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 3.8 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 2.4 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 2.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.2 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.5 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 3.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 1.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.3 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 2.1 GO:0072189 ureter development(GO:0072189)
0.1 0.8 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0010159 specification of organ position(GO:0010159)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 1.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.3 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.6 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 1.0 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.5 GO:0001554 luteolysis(GO:0001554)
0.0 0.4 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.3 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0072719 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.0 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.8 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 2.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 1.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.5 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.7 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 2.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.9 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.3 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 1.8 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.6 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.5 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 3.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 1.0 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 1.0 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.5 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:1902527 female meiosis I(GO:0007144) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.0 GO:0014736 regulation of muscle atrophy(GO:0014735) negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.2 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.9 13.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.7 2.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.6 3.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.4 4.9 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.7 GO:0031251 PAN complex(GO:0031251)
0.2 1.4 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2 4.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 1.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 2.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 3.5 GO:0042627 chylomicron(GO:0042627)
0.2 2.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 1.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.8 GO:0030914 STAGA complex(GO:0030914)
0.1 1.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.9 GO:0032009 early phagosome(GO:0032009)
0.1 1.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 2.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 3.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.8 GO:0043203 axon hillock(GO:0043203)
0.1 4.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.6 GO:0045160 myosin I complex(GO:0045160)
0.1 1.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.2 GO:0005638 lamin filament(GO:0005638)
0.1 0.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 7.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.9 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 13.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 3.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 8.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 2.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 34.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 7.8 GO:0072562 blood microparticle(GO:0072562)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 2.1 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 3.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.2 GO:0005901 caveola(GO:0005901)
0.0 2.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.3 GO:0005581 collagen trimer(GO:0005581)
0.0 27.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 3.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.8 5.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
1.1 4.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.1 5.6 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.1 4.5 GO:0001855 complement component C4b binding(GO:0001855)
0.8 2.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.8 3.8 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.7 2.2 GO:0033791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity(GO:0033791)
0.7 2.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.7 3.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.7 2.0 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.6 3.0 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.6 1.7 GO:0008892 guanine deaminase activity(GO:0008892)
0.6 3.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.5 4.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.5 3.9 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 4.2 GO:0005497 androgen binding(GO:0005497)
0.5 1.4 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.5 3.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 3.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.4 1.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.4 4.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.4 2.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 1.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.4 2.9 GO:0015254 glycerol channel activity(GO:0015254)
0.4 3.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.4 3.3 GO:0032810 sterol response element binding(GO:0032810)
0.3 1.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 4.5 GO:0004075 biotin carboxylase activity(GO:0004075)
0.3 0.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 1.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 1.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 2.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 0.8 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 0.8 GO:0017129 triglyceride binding(GO:0017129)
0.2 6.1 GO:0070330 aromatase activity(GO:0070330)
0.2 1.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 1.5 GO:0016936 galactoside binding(GO:0016936)
0.2 0.9 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 0.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 2.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 4.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 0.6 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.2 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 6.4 GO:0035497 cAMP response element binding(GO:0035497)
0.2 0.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 1.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 1.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 0.7 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.2 0.5 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.2 2.4 GO:0008430 selenium binding(GO:0008430)
0.2 1.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 0.6 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.9 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.5 GO:0015288 porin activity(GO:0015288)
0.1 0.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 2.5 GO:0042301 phosphate ion binding(GO:0042301)
0.1 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0016531 copper chaperone activity(GO:0016531)
0.1 2.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 16.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 4.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 3.0 GO:0001848 complement binding(GO:0001848)
0.1 0.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 3.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 0.4 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.3 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 1.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 19.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 2.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0008434 calcitriol receptor activity(GO:0008434) lithocholic acid receptor activity(GO:0038186) calcitriol binding(GO:1902098) lithocholic acid binding(GO:1902121)
0.0 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.3 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 2.7 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.6 GO:0015923 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.0 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 2.6 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 2.5 GO:0005507 copper ion binding(GO:0005507)
0.0 1.5 GO:0043531 ADP binding(GO:0043531)
0.0 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 3.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 40.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.9 ST ADRENERGIC Adrenergic Pathway
0.1 2.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 8.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 16.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 13.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.6 10.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.6 13.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 4.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 5.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 3.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 2.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 3.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 3.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 6.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 7.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 7.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 8.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 2.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 6.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 5.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.3 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI