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Illumina Body Map 2 (GSE30611)

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Results for SCRT1_SCRT2

Z-value: 1.74

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
ENSG00000261678.3 scratch family transcriptional repressor 1
ENSG00000215397.4 scratch family transcriptional repressor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SCRT1hg38_v1_chr8_-_144336451_1443365030.468.5e-03Click!
SCRT2hg38_v1_chr20_-_675793_675808-0.163.9e-01Click!

Activity profile of SCRT1_SCRT2 motif

Sorted Z-values of SCRT1_SCRT2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41256921 12.25 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
ubiquitin C-terminal hydrolase L1
chr17_+_39628496 10.10 ENST00000394265.5
ENST00000394267.2
protein phosphatase 1 regulatory inhibitor subunit 1B
chr12_-_15221394 7.76 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RAS like estrogen regulated growth inhibitor
chr1_+_15756659 6.76 ENST00000375771.5
filamin binding LIM protein 1
chr3_+_16174628 6.34 ENST00000339732.10
polypeptide N-acetylgalactosaminyltransferase 15
chr3_+_181711915 5.40 ENST00000325404.3
SRY-box transcription factor 2
chr5_+_15500172 5.17 ENST00000504595.2
F-box and leucine rich repeat protein 7
chr3_+_16174703 5.12 ENST00000437509.3
polypeptide N-acetylgalactosaminyltransferase 15
chr6_+_121435595 4.77 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr4_-_5888400 4.63 ENST00000397890.6
collapsin response mediator protein 1
chr19_-_7926106 4.38 ENST00000318978.6
cortexin 1
chr7_+_20330893 4.32 ENST00000222573.5
integrin subunit beta 8
chr8_+_97869040 4.25 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
matrilin 2
chr17_+_55266216 4.24 ENST00000573945.5
HLF transcription factor, PAR bZIP family member
chr11_-_117876892 4.20 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr15_-_29821473 4.11 ENST00000400011.6
tight junction protein 1
chr11_-_117876719 4.08 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr15_-_29822028 3.75 ENST00000545208.6
tight junction protein 1
chrX_-_100731504 3.71 ENST00000372989.5
ENST00000276141.10
synaptotagmin like 4
chr8_+_74824526 3.60 ENST00000649643.1
ENST00000260113.7
peptidase inhibitor 15
chr11_-_117876612 3.58 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr7_-_28958321 3.45 ENST00000539664.3
TLR4 interactor with leucine rich repeats
chr1_+_15756603 3.28 ENST00000496928.6
ENST00000508310.5
filamin binding LIM protein 1
chrX_-_55030970 3.24 ENST00000493869.2
ENST00000396198.7
ENST00000650242.1
ENST00000335854.8
ENST00000477869.6
ENST00000455688.2
ENST00000644983.1
5'-aminolevulinate synthase 2
chr4_+_41538143 3.21 ENST00000503057.6
ENST00000511496.5
LIM and calponin homology domains 1
chr15_+_63597353 3.17 ENST00000360587.2
F-box and leucine rich repeat protein 22
chr12_-_32896757 3.10 ENST00000070846.11
ENST00000340811.9
plakophilin 2
chr5_-_74640719 3.05 ENST00000302351.9
ENST00000509127.2
ectodermal-neural cortex 1
chr11_-_117876683 3.05 ENST00000530956.6
FXYD domain containing ion transport regulator 6
chr2_-_240820945 2.96 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chr7_-_122886706 2.91 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr1_+_15756628 2.81 ENST00000510393.5
ENST00000430076.5
filamin binding LIM protein 1
chr2_+_17878637 2.79 ENST00000304101.9
potassium voltage-gated channel modifier subfamily S member 3
chrX_-_100732100 2.75 ENST00000372981.1
ENST00000263033.9
synaptotagmin like 4
chr4_-_140427635 2.68 ENST00000325617.10
ENST00000414773.5
calmegin
chr2_-_223602284 2.66 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr15_+_43593054 2.62 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr5_-_74640575 2.60 ENST00000651128.1
ectodermal-neural cortex 1
chr15_+_63597378 2.55 ENST00000638704.2
ENST00000534939.2
F-box and leucine rich repeat protein 22
chr11_-_117877463 2.52 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr16_+_46884675 2.52 ENST00000562132.5
ENST00000440783.2
glutamic--pyruvic transaminase 2
chrX_-_31266925 2.50 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr3_-_62875337 2.46 ENST00000357948.7
ENST00000612439.4
ENST00000383710.9
calcium dependent secretion activator
chr20_-_23421409 2.42 ENST00000377026.4
ENST00000398425.7
ENST00000432543.6
ENST00000617876.4
NSF attachment protein beta
chr11_+_61816249 2.34 ENST00000257261.10
fatty acid desaturase 2
chr11_-_111923722 2.34 ENST00000527950.5
crystallin alpha B
chr8_+_119208322 2.32 ENST00000614891.5
mal, T cell differentiation protein 2
chr5_-_74640649 2.28 ENST00000537006.1
ectodermal-neural cortex 1
chr2_-_240820205 2.27 ENST00000647731.1
ENST00000648680.1
ENST00000649306.1
ENST00000648129.1
ENST00000498729.9
ENST00000320389.12
ENST00000648364.1
ENST00000647885.1
ENST00000404283.9
ENST00000649096.1
kinesin family member 1A
chr11_-_8718018 2.17 ENST00000533020.5
DENN domain containing 2B
chr10_+_125896549 2.16 ENST00000368693.6
fibronectin type III and ankyrin repeat domains 1
chrX_-_70931089 2.16 ENST00000374299.8
ENST00000298085.4
solute carrier family 7 member 3
chr17_-_10198592 2.15 ENST00000432992.7
growth arrest specific 7
chr4_+_164754045 2.13 ENST00000515485.5
small integral membrane protein 31
chr19_-_46471484 2.13 ENST00000313683.15
ENST00000602246.1
PNMA family member 8A
chr9_+_131096476 2.11 ENST00000372309.7
ENST00000247291.8
ENST00000372302.5
ENST00000372300.5
ENST00000372298.1
allograft inflammatory factor 1 like
chr19_-_46471407 2.10 ENST00000438932.2
PNMA family member 8A
chr8_-_33473076 2.10 ENST00000524021.1
ENST00000327671.10
fucosyltransferase 10
chr20_-_45348414 2.09 ENST00000372733.3
syndecan 4
chr9_+_122941003 2.09 ENST00000373647.9
ENST00000402311.5
RAB GTPase activating protein 1
chr4_-_89836213 2.08 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr3_-_143848442 2.05 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr4_-_109302643 1.99 ENST00000399126.1
ENST00000505591.1
ENST00000399132.6
collagen type XXV alpha 1 chain
chr14_-_23572975 1.94 ENST00000544177.1
junctophilin 4
chr4_-_52038260 1.94 ENST00000381431.10
sarcoglycan beta
chr15_-_29822077 1.93 ENST00000677774.1
tight junction protein 1
chr4_-_109302707 1.92 ENST00000642955.1
collagen type XXV alpha 1 chain
chr5_+_126423176 1.87 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr11_+_61816366 1.86 ENST00000522056.5
fatty acid desaturase 2
chrX_+_55717796 1.86 ENST00000262850.7
Ras related GTP binding B
chr3_+_167735704 1.84 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr16_+_981762 1.83 ENST00000293894.4
SRY-box transcription factor 8
chrX_-_52069172 1.82 ENST00000486010.1
ENST00000497164.5
ENST00000360134.10
ENST00000485287.5
ENST00000335504.9
MAGE family member D4B
chr15_-_82680407 1.82 ENST00000660624.1
ENST00000666894.1
adaptor related protein complex 3 subunit beta 2
chr11_+_69641146 1.78 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr8_-_126557691 1.76 ENST00000652209.1
LRAT domain containing 2
chr14_+_23306816 1.76 ENST00000678311.1
ENST00000557579.2
ENST00000250405.10
ENST00000679000.1
ENST00000557236.6
ENST00000678502.1
ENST00000553781.5
BCL2 like 2
BCL2L2-PABPN1 readthrough
chr4_+_164754116 1.71 ENST00000507311.1
small integral membrane protein 31
chr10_-_114404480 1.71 ENST00000419268.1
ENST00000304129.9
actin filament associated protein 1 like 2
chr2_+_188291854 1.71 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr12_-_21657792 1.70 ENST00000396076.5
lactate dehydrogenase B
chr12_-_21657831 1.66 ENST00000450584.5
ENST00000350669.5
ENST00000673047.2
lactate dehydrogenase B
chr12_+_78036248 1.64 ENST00000644176.1
neuron navigator 3
chr5_-_151686908 1.64 ENST00000231061.9
secreted protein acidic and cysteine rich
chr1_-_94927079 1.62 ENST00000370206.9
ENST00000394202.8
calponin 3
chr7_-_122886439 1.60 ENST00000412584.6
ENST00000449022.7
calcium dependent secretion activator 2
chr11_-_104164361 1.60 ENST00000302251.9
platelet derived growth factor D
chr5_+_126423363 1.60 ENST00000285689.8
GRAM domain containing 2B
chr15_+_43692886 1.59 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr3_+_167735238 1.54 ENST00000472941.5
serpin family I member 1
chr18_-_67516707 1.54 ENST00000310045.9
dermatan sulfate epimerase like
chr5_-_151686953 1.51 ENST00000538026.5
ENST00000522348.1
ENST00000521569.1
secreted protein acidic and cysteine rich
chr12_+_81078035 1.49 ENST00000261206.7
ENST00000548058.6
acyl-CoA synthetase short chain family member 3
chr3_-_62875204 1.48 ENST00000283269.13
calcium dependent secretion activator
chrX_-_151974668 1.46 ENST00000370328.4
gamma-aminobutyric acid type A receptor subunit epsilon
chr6_-_56843638 1.44 ENST00000421834.6
ENST00000370788.6
dystonin
chr13_-_25172278 1.43 ENST00000515384.2
ENST00000357816.2
APC membrane recruitment protein 2
chr19_-_409134 1.43 ENST00000332235.8
C2 calcium dependent domain containing 4C
chr12_-_70754631 1.43 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr8_-_109975757 1.42 ENST00000524391.6
potassium voltage-gated channel modifier subfamily V member 1
chr5_-_35938572 1.42 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr11_+_32091065 1.38 ENST00000054950.4
reticulocalbin 1
chr5_+_126423122 1.35 ENST00000515200.5
GRAM domain containing 2B
chr4_-_140427608 1.35 ENST00000509477.1
calmegin
chr5_+_32710630 1.33 ENST00000326958.5
natriuretic peptide receptor 3
chrX_+_52184874 1.32 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chr19_-_58098203 1.30 ENST00000600845.1
ENST00000240727.10
ENST00000600897.5
ENST00000421612.6
ENST00000601063.1
ENST00000601144.6
zinc finger and SCAN domain containing 18
chr19_+_40601342 1.29 ENST00000396819.8
latent transforming growth factor beta binding protein 4
chr1_+_156338455 1.28 ENST00000368253.6
ENST00000470342.5
ENST00000368254.6
TSSK6 activating cochaperone
chrX_+_51893533 1.27 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr2_+_100821025 1.27 ENST00000427413.5
neuronal PAS domain protein 2
chr2_+_172735838 1.26 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr17_+_80220406 1.24 ENST00000573809.5
ENST00000361193.8
ENST00000574967.5
ENST00000576126.5
ENST00000411502.7
ENST00000546047.6
ENST00000572725.5
solute carrier family 26 member 11
chr2_-_110204967 1.20 ENST00000355301.8
ENST00000676053.1
ENST00000675067.1
ENST00000676028.1
ENST00000417665.5
ENST00000418527.1
ENST00000445609.7
ENST00000316534.8
ENST00000393272.7
nephrocystin 1
chr2_+_188291994 1.17 ENST00000409927.5
ENST00000409805.5
GULP PTB domain containing engulfment adaptor 1
chr3_-_151461011 1.17 ENST00000282466.4
immunoglobulin superfamily member 10
chr16_+_1989949 1.15 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr2_-_179861604 1.13 ENST00000410066.7
zinc finger protein 385B
chr8_-_138497254 1.10 ENST00000395297.6
family with sequence similarity 135 member B
chr6_-_31729785 1.09 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr1_+_156338619 1.08 ENST00000481479.5
ENST00000368252.5
ENST00000466306.5
ENST00000368251.1
TSSK6 activating cochaperone
chr18_+_77249844 1.08 ENST00000299727.5
galanin receptor 1
chr3_-_180036770 1.07 ENST00000263962.12
peroxisomal biogenesis factor 5 like
chr11_-_71448315 1.07 ENST00000525346.5
ENST00000531364.5
ENST00000529990.5
ENST00000527316.5
ENST00000355527.8
ENST00000407721.6
7-dehydrocholesterol reductase
chr10_+_80131660 1.05 ENST00000372270.6
placenta associated 9
chr19_-_6459735 1.04 ENST00000334510.9
ENST00000301454.9
solute carrier family 25 member 23
chr9_+_96450115 1.03 ENST00000375249.5
ENST00000375251.7
hyaluronan binding protein 4
chrX_+_52184904 1.00 ENST00000375626.7
ENST00000467526.1
MAGE family member D4
chr1_+_77283071 0.98 ENST00000478407.1
adenylate kinase 5
chr1_+_24319342 0.98 ENST00000361548.9
grainyhead like transcription factor 3
chr5_-_115296610 0.97 ENST00000379611.10
ENST00000506442.5
coiled-coil domain containing 112
chr14_+_99793375 0.97 ENST00000262233.11
ENST00000556714.5
EMAP like 1
chr17_+_65137408 0.96 ENST00000443584.7
ENST00000449996.7
regulator of G protein signaling 9
chrX_-_153875847 0.95 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr2_+_24175042 0.93 ENST00000295150.8
family with sequence similarity 228 member A
chr2_+_172735912 0.93 ENST00000409036.5
Rap guanine nucleotide exchange factor 4
chr8_+_81732434 0.89 ENST00000297265.5
charged multivesicular body protein 4C
chr1_-_212414815 0.89 ENST00000261455.9
ENST00000535273.2
proton activated chloride channel 1
chr7_+_80199266 0.89 ENST00000647672.1
G protein subunit alpha i1
chrX_-_31266857 0.89 ENST00000378702.8
ENST00000361471.8
dystrophin
chr11_+_111976902 0.89 ENST00000614104.4
DIX domain containing 1
chr12_+_48818478 0.88 ENST00000547818.5
ENST00000301050.7
ENST00000547392.5
calcium voltage-gated channel auxiliary subunit beta 3
chr11_-_61816761 0.87 ENST00000491310.5
fatty acid desaturase 1
chr8_-_81732327 0.86 ENST00000520604.5
ENST00000521742.5
ENST00000520635.5
zinc finger AN1-type containing 1
chr1_-_9069608 0.85 ENST00000377424.9
solute carrier family 2 member 5
chr17_-_37745018 0.82 ENST00000613727.4
ENST00000614313.4
ENST00000617811.5
ENST00000621123.4
HNF1 homeobox B
chr6_-_31729478 0.82 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr5_-_147831663 0.82 ENST00000296695.10
serine peptidase inhibitor Kazal type 1
chr6_-_135497230 0.81 ENST00000681365.1
Abelson helper integration site 1
chr7_+_73827737 0.80 ENST00000435050.1
claudin 4
chr1_-_25875669 0.79 ENST00000675840.1
progestin and adipoQ receptor family member 7
chr6_-_77463485 0.78 ENST00000369947.5
5-hydroxytryptamine receptor 1B
chr2_-_19990058 0.78 ENST00000281405.9
ENST00000345530.8
WD repeat domain 35
chr20_+_31440626 0.77 ENST00000376309.4
defensin beta 123
chr15_+_76059973 0.77 ENST00000388942.8
transmembrane protein 266
chr19_-_11262499 0.77 ENST00000294618.12
dedicator of cytokinesis 6
chr12_-_70609788 0.76 ENST00000547715.1
ENST00000538708.5
ENST00000550857.5
ENST00000261266.9
protein tyrosine phosphatase receptor type B
chr16_+_25111703 0.75 ENST00000380966.8
ENST00000399069.8
leucine carboxyl methyltransferase 1
chr18_+_45727329 0.74 ENST00000590246.6
solute carrier family 14 member 1 (Kidd blood group)
chr11_-_71448406 0.74 ENST00000682708.1
ENST00000683287.1
ENST00000683714.1
ENST00000682880.1
7-dehydrocholesterol reductase
chr2_+_37196475 0.74 ENST00000397064.6
ENST00000402297.6
ENST00000406711.5
ENST00000392061.6
ENST00000397226.2
CEBPZ opposite strand
chr7_+_73828160 0.74 ENST00000431918.1
claudin 4
chr14_+_67241417 0.74 ENST00000556345.6
ENST00000555925.5
ENST00000261681.9
ENST00000557783.1
membrane palmitoylated protein 5
chr6_+_70413462 0.73 ENST00000418814.7
ENST00000515280.5
ENST00000507085.5
ENST00000457062.6
ENST00000361499.7
family with sequence similarity 135 member A
chr15_-_82349437 0.72 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
golgin A6 family like 10
chr3_+_133746385 0.72 ENST00000482271.5
ENST00000402696.9
transferrin
chr14_+_67241531 0.71 ENST00000678380.1
membrane palmitoylated protein 5
chr10_+_24208774 0.71 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr17_+_65137344 0.71 ENST00000262406.10
regulator of G protein signaling 9
chr6_-_135498417 0.71 ENST00000681022.1
ENST00000680033.1
Abelson helper integration site 1
chr15_+_84235773 0.71 ENST00000510439.7
ENST00000422563.6
golgin A6 family like 4
chr10_+_35195124 0.70 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr5_-_115296261 0.68 ENST00000395557.4
coiled-coil domain containing 112
chr3_-_180036918 0.67 ENST00000465751.5
ENST00000467460.6
ENST00000472994.5
peroxisomal biogenesis factor 5 like
chr5_+_73626158 0.67 ENST00000296794.10
ENST00000545377.5
ENST00000509848.5
ENST00000513042.7
Rho guanine nucleotide exchange factor 28
chr6_+_70413417 0.66 ENST00000505769.5
ENST00000515323.5
family with sequence similarity 135 member A
chr8_+_74320613 0.65 ENST00000675821.1
ganglioside induced differentiation associated protein 1
chr3_-_186362223 0.65 ENST00000265022.8
diacylglycerol kinase gamma
chr17_-_64263221 0.65 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
testis expressed 2
chr17_-_46979240 0.64 ENST00000322329.5
reprimo like
chr5_-_111756245 0.62 ENST00000447165.6
neuronal regeneration related protein
chr1_-_93847150 0.61 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr3_+_26622800 0.61 ENST00000396641.6
leucine rich repeat containing 3B
chr18_+_63949279 0.61 ENST00000408945.5
histocompatibility minor serpin domain containing
chr22_+_42553994 0.60 ENST00000407614.8
ENST00000335879.5
serine hydrolase like 2
chr12_-_52517929 0.60 ENST00000548409.5
keratin 5
chr6_-_31729260 0.59 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr3_-_79767987 0.59 ENST00000464233.6
roundabout guidance receptor 1
chr1_+_24319511 0.58 ENST00000356046.6
grainyhead like transcription factor 3
chr2_-_119158744 0.58 ENST00000272520.4
complement C1q like 2
chr1_+_179882275 0.58 ENST00000606911.7
ENST00000271583.7
torsin 1A interacting protein 1
chr14_+_67241278 0.58 ENST00000676464.1
membrane palmitoylated protein 5
chr7_+_130486324 0.57 ENST00000427521.6
ENST00000378576.9
mesoderm specific transcript
chr17_-_2511875 0.57 ENST00000263092.11
ENST00000576976.2
methyltransferase like 16
chr15_-_44194407 0.57 ENST00000484674.5
FERM domain containing 5
chr1_-_20717996 0.57 ENST00000400463.8
ENST00000247986.2
kinesin family member 17
chr6_-_99515410 0.56 ENST00000369233.6
ENST00000500704.7
ENST00000329966.10
ubiquitin specific peptidase 45
chr7_+_130486171 0.55 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr14_+_71933116 0.55 ENST00000553530.5
ENST00000556437.5
regulator of G protein signaling 6
chrX_-_42778155 0.55 ENST00000378131.4
PPP1R2C family member C

Network of associatons between targets according to the STRING database.

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.8 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.5 12.2 GO:0007412 axon target recognition(GO:0007412)
1.4 4.2 GO:0031104 dendrite regeneration(GO:0031104)
1.2 4.8 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.2 4.6 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
1.0 8.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.7 10.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.7 12.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.6 3.1 GO:0048496 adherens junction maintenance(GO:0034334) maintenance of organ identity(GO:0048496)
0.6 1.8 GO:0072034 renal vesicle induction(GO:0072034)
0.6 5.2 GO:0010265 SCF complex assembly(GO:0010265)
0.6 6.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.5 1.6 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.5 7.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5 2.5 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.4 2.2 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.4 1.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.4 3.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.4 1.5 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.4 1.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.3 2.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 2.1 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 1.0 GO:0097274 urea homeostasis(GO:0097274)
0.3 1.0 GO:0006173 dADP biosynthetic process(GO:0006173)
0.3 0.9 GO:0006481 C-terminal protein methylation(GO:0006481)
0.3 1.8 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.3 3.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.3 2.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.3 3.9 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.3 6.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 1.7 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 1.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 1.1 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.2 3.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 1.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 3.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 0.9 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.2 2.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.1 GO:0097319 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.2 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 0.8 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.2 4.9 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.2 0.8 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.2 17.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 3.4 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.6 GO:0061642 chemoattraction of serotonergic neuron axon(GO:0036517) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 2.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.6 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.4 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 1.9 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 1.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.7 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 2.7 GO:0006527 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.1 7.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 2.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 2.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.1 2.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.6 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.1 1.8 GO:0070141 Leydig cell differentiation(GO:0033327) positive regulation of mammary gland epithelial cell proliferation(GO:0033601) response to UV-A(GO:0070141)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 3.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 1.6 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 8.9 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.4 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.5 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.1 1.2 GO:0019532 oxalate transport(GO:0019532)
0.1 1.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.2 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) hard palate development(GO:0060022) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.6 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.3 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.4 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.3 GO:0051775 response to redox state(GO:0051775)
0.1 2.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.9 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 1.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.4 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.9 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 3.5 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.4 GO:0007398 ectoderm development(GO:0007398)
0.0 1.7 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.5 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 1.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.0 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 7.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 2.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 2.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.7 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 2.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 1.1 GO:0021762 substantia nigra development(GO:0021762)
0.0 1.0 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 6.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.2 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.9 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 1.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 3.2 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 1.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 14.6 GO:0005921 gap junction(GO:0005921)
0.3 1.9 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 3.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 11.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 20.7 GO:1904115 axon cytoplasm(GO:1904115)
0.2 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 3.4 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.6 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 1.9 GO:0030314 junctional membrane complex(GO:0030314)
0.1 2.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 9.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 13.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.2 GO:0043219 lateral loop(GO:0043219)
0.1 3.1 GO:0030057 desmosome(GO:0030057)
0.1 7.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.5 GO:0036038 MKS complex(GO:0036038)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 1.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 4.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0005786 signal recognition particle receptor complex(GO:0005785) signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.1 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 4.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 4.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 3.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 6.0 GO:0030496 midbody(GO:0030496)
0.0 3.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.0 GO:0098793 presynapse(GO:0098793)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 9.2 GO:0030133 transport vesicle(GO:0030133)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 2.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.1 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
2.0 12.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.9 4.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.8 2.5 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.8 3.9 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.6 3.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.6 2.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.5 4.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.5 17.5 GO:0031005 filamin binding(GO:0031005)
0.4 11.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 2.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 2.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.3 3.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 0.9 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.3 2.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.3 1.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 3.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 0.5 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 3.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 1.6 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 0.6 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 17.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 1.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.2 5.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 0.9 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.2 0.5 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.6 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.2 5.4 GO:0035198 miRNA binding(GO:0035198)
0.1 0.5 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.1 2.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 2.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 3.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 2.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0015265 urea channel activity(GO:0015265)
0.1 7.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.7 GO:0051400 BH domain binding(GO:0051400)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 3.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 1.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.8 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 2.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 2.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 3.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 1.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 6.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 4.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 2.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 3.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 4.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 3.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 8.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.3 GO:0051087 chaperone binding(GO:0051087)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 5.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 9.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.0 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 2.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 3.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 6.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 13.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 4.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 4.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 6.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 3.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 3.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF