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Illumina Body Map 2 (GSE30611)
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Results for SHOX
Z-value: 1.46
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Transcription factors associated with SHOX
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SHOX
|
ENSG00000185960.14 | short stature homeobox |
|
SHOX
|
ENSG00000185960.14 | short stature homeobox |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SHOX | hg38_v1_chrX_+_630789_630807 | 0.11 | 5.6e-01 | Click! |
Activity profile of SHOX motif
Sorted Z-values of SHOX motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_-_46142834 | 9.42 |
ENST00000674665.1
|
LCP1
|
lymphocyte cytosolic protein 1 |
| chr4_-_25863537 | 8.29 |
ENST00000502949.5
ENST00000264868.9 ENST00000513691.1 ENST00000514872.1 |
SEL1L3
|
SEL1L family member 3 |
| chr2_+_90038848 | 6.14 |
ENST00000390270.2
|
IGKV3D-20
|
immunoglobulin kappa variable 3D-20 |
| chr3_-_27722699 | 5.84 |
ENST00000461503.2
|
EOMES
|
eomesodermin |
| chr4_-_36243939 | 5.69 |
ENST00000506189.1
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| chr15_+_74788542 | 5.69 |
ENST00000567571.5
|
CSK
|
C-terminal Src kinase |
| chr12_-_10130143 | 5.64 |
ENST00000298523.9
ENST00000396484.6 ENST00000310002.4 ENST00000304084.13 |
CLEC7A
|
C-type lectin domain containing 7A |
| chr3_-_27722316 | 5.37 |
ENST00000449599.4
|
EOMES
|
eomesodermin |
| chr15_+_58138368 | 5.30 |
ENST00000219919.9
ENST00000536493.1 |
AQP9
|
aquaporin 9 |
| chr14_-_106038355 | 5.06 |
ENST00000390597.3
|
IGHV2-5
|
immunoglobulin heavy variable 2-5 |
| chr1_-_183569186 | 5.05 |
ENST00000420553.5
ENST00000419402.1 |
NCF2
|
neutrophil cytosolic factor 2 |
| chr10_-_72088504 | 4.78 |
ENST00000536168.2
|
SPOCK2
|
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 |
| chr1_-_150765735 | 4.62 |
ENST00000679898.1
ENST00000448301.7 ENST00000680664.1 ENST00000679512.1 ENST00000368985.8 ENST00000679582.1 |
CTSS
|
cathepsin S |
| chr2_+_87338511 | 4.55 |
ENST00000421835.2
|
IGKV3OR2-268
|
immunoglobulin kappa variable 3/OR2-268 (non-functional) |
| chr12_-_10130241 | 4.45 |
ENST00000353231.9
ENST00000525605.1 |
CLEC7A
|
C-type lectin domain containing 7A |
| chr13_-_41019289 | 4.44 |
ENST00000239882.7
|
ELF1
|
E74 like ETS transcription factor 1 |
| chr2_+_90172802 | 4.35 |
ENST00000390277.3
|
IGKV3D-11
|
immunoglobulin kappa variable 3D-11 |
| chr12_-_89352395 | 4.33 |
ENST00000308385.6
|
DUSP6
|
dual specificity phosphatase 6 |
| chr1_-_113871665 | 4.31 |
ENST00000528414.5
ENST00000460620.5 ENST00000359785.10 ENST00000420377.6 ENST00000525799.1 ENST00000538253.5 |
PTPN22
|
protein tyrosine phosphatase non-receptor type 22 |
| chr7_+_50308672 | 4.28 |
ENST00000439701.2
ENST00000438033.5 ENST00000492782.6 |
IKZF1
|
IKAROS family zinc finger 1 |
| chr2_-_181680490 | 4.28 |
ENST00000684145.1
ENST00000295108.4 ENST00000684079.1 ENST00000683430.1 |
CERKL
NEUROD1
|
ceramide kinase like neuronal differentiation 1 |
| chr6_-_32941018 | 4.06 |
ENST00000418107.3
|
HLA-DMB
|
major histocompatibility complex, class II, DM beta |
| chr12_-_89352487 | 4.03 |
ENST00000548755.1
ENST00000279488.8 |
DUSP6
|
dual specificity phosphatase 6 |
| chr7_+_116222804 | 4.02 |
ENST00000393481.6
|
TES
|
testin LIM domain protein |
| chr11_-_117876892 | 3.99 |
ENST00000539526.5
|
FXYD6
|
FXYD domain containing ion transport regulator 6 |
| chr1_+_198638968 | 3.92 |
ENST00000348564.11
ENST00000530727.5 ENST00000442510.8 ENST00000645247.1 ENST00000367367.8 ENST00000367364.5 ENST00000413409.6 |
PTPRC
|
protein tyrosine phosphatase receptor type C |
| chr16_+_11965193 | 3.89 |
ENST00000053243.6
ENST00000396495.3 |
TNFRSF17
|
TNF receptor superfamily member 17 |
| chr18_+_59899988 | 3.83 |
ENST00000316660.7
ENST00000269518.9 |
PMAIP1
|
phorbol-12-myristate-13-acetate-induced protein 1 |
| chr11_-_117876719 | 3.81 |
ENST00000529335.6
ENST00000260282.8 |
FXYD6
|
FXYD domain containing ion transport regulator 6 |
| chr15_+_58138169 | 3.76 |
ENST00000558772.5
|
AQP9
|
aquaporin 9 |
| chrX_-_19799751 | 3.74 |
ENST00000379698.8
|
SH3KBP1
|
SH3 domain containing kinase binding protein 1 |
| chr4_-_56681288 | 3.73 |
ENST00000556376.6
ENST00000420433.6 |
HOPX
|
HOP homeobox |
| chr11_-_117877463 | 3.69 |
ENST00000527717.5
|
FXYD6
|
FXYD domain containing ion transport regulator 6 |
| chrX_+_135520616 | 3.64 |
ENST00000370752.4
ENST00000639893.2 |
INTS6L
|
integrator complex subunit 6 like |
| chr2_+_90234809 | 3.64 |
ENST00000443397.5
|
IGKV3D-7
|
immunoglobulin kappa variable 3D-7 |
| chr13_-_99258366 | 3.52 |
ENST00000397470.5
ENST00000397473.7 |
GPR18
|
G protein-coupled receptor 18 |
| chr4_-_56681588 | 3.43 |
ENST00000554144.5
ENST00000381260.7 |
HOPX
|
HOP homeobox |
| chr7_+_142300924 | 3.42 |
ENST00000455382.2
|
TRBV2
|
T cell receptor beta variable 2 |
| chr1_-_92486916 | 3.39 |
ENST00000294702.6
|
GFI1
|
growth factor independent 1 transcriptional repressor |
| chrX_-_154371210 | 3.37 |
ENST00000369856.8
ENST00000422373.6 ENST00000360319.9 |
FLNA
|
filamin A |
| chr1_-_150765785 | 3.35 |
ENST00000680311.1
ENST00000681728.1 ENST00000680288.1 |
CTSS
|
cathepsin S |
| chr6_+_113857333 | 3.34 |
ENST00000612661.2
|
MARCKS
|
myristoylated alanine rich protein kinase C substrate |
| chr2_+_68734773 | 3.25 |
ENST00000409202.8
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr2_+_68734861 | 3.20 |
ENST00000467265.5
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr19_+_49513353 | 3.15 |
ENST00000596975.5
|
FCGRT
|
Fc fragment of IgG receptor and transporter |
| chr10_+_110005804 | 3.12 |
ENST00000360162.7
|
ADD3
|
adducin 3 |
| chr6_+_31615984 | 3.11 |
ENST00000376049.4
|
AIF1
|
allograft inflammatory factor 1 |
| chr11_-_33892010 | 3.04 |
ENST00000257818.3
|
LMO2
|
LIM domain only 2 |
| chr11_-_117876683 | 3.01 |
ENST00000530956.6
|
FXYD6
|
FXYD domain containing ion transport regulator 6 |
| chr3_+_122055355 | 3.00 |
ENST00000330540.7
ENST00000469710.5 ENST00000493101.5 |
CD86
|
CD86 molecule |
| chr2_-_88861563 | 2.92 |
ENST00000624935.3
ENST00000390241.3 |
ENSG00000240040.6
IGKJ2
|
novel transcript immunoglobulin kappa joining 2 |
| chr2_-_144520006 | 2.87 |
ENST00000303660.8
|
ZEB2
|
zinc finger E-box binding homeobox 2 |
| chr7_-_93117956 | 2.85 |
ENST00000446617.1
ENST00000379958.3 ENST00000620985.4 |
SAMD9
|
sterile alpha motif domain containing 9 |
| chr5_+_119333151 | 2.84 |
ENST00000513374.1
|
TNFAIP8
|
TNF alpha induced protein 8 |
| chr2_+_151357583 | 2.83 |
ENST00000243347.5
|
TNFAIP6
|
TNF alpha induced protein 6 |
| chr3_+_141387801 | 2.82 |
ENST00000514251.5
|
ZBTB38
|
zinc finger and BTB domain containing 38 |
| chr6_+_106360668 | 2.78 |
ENST00000633556.3
|
CRYBG1
|
crystallin beta-gamma domain containing 1 |
| chr10_-_54801262 | 2.71 |
ENST00000373965.6
ENST00000616114.4 ENST00000621708.4 ENST00000495484.5 ENST00000395440.5 ENST00000395442.5 ENST00000617271.4 ENST00000395446.5 ENST00000409834.5 ENST00000361849.7 ENST00000373957.7 ENST00000395430.5 ENST00000395433.5 ENST00000437009.5 |
PCDH15
|
protocadherin related 15 |
| chr3_+_4680617 | 2.69 |
ENST00000648212.1
|
ITPR1
|
inositol 1,4,5-trisphosphate receptor type 1 |
| chr6_+_130018565 | 2.69 |
ENST00000361794.7
ENST00000526087.5 ENST00000533560.5 |
L3MBTL3
|
L3MBTL histone methyl-lysine binding protein 3 |
| chr15_-_55270383 | 2.68 |
ENST00000396307.6
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr17_-_40799939 | 2.67 |
ENST00000306658.8
|
KRT28
|
keratin 28 |
| chr14_+_21841182 | 2.67 |
ENST00000390433.1
|
TRAV12-1
|
T cell receptor alpha variable 12-1 |
| chr4_-_142305935 | 2.67 |
ENST00000511838.5
|
INPP4B
|
inositol polyphosphate-4-phosphatase type II B |
| chr9_+_122371014 | 2.66 |
ENST00000362012.7
|
PTGS1
|
prostaglandin-endoperoxide synthase 1 |
| chr1_+_65992389 | 2.65 |
ENST00000423207.6
|
PDE4B
|
phosphodiesterase 4B |
| chr2_+_169069537 | 2.60 |
ENST00000428522.5
ENST00000450153.1 ENST00000674881.1 ENST00000421653.5 |
DHRS9
|
dehydrogenase/reductase 9 |
| chr6_+_26402237 | 2.57 |
ENST00000476549.6
ENST00000450085.6 ENST00000425234.6 ENST00000427334.5 ENST00000506698.1 ENST00000289361.11 |
BTN3A1
|
butyrophilin subfamily 3 member A1 |
| chr1_-_17439657 | 2.53 |
ENST00000375436.9
|
RCC2
|
regulator of chromosome condensation 2 |
| chr7_-_13986439 | 2.52 |
ENST00000443608.5
ENST00000438956.5 |
ETV1
|
ETS variant transcription factor 1 |
| chrX_-_13817027 | 2.51 |
ENST00000493677.5
ENST00000355135.6 ENST00000316715.9 |
GPM6B
|
glycoprotein M6B |
| chrX_+_108045050 | 2.51 |
ENST00000458383.1
ENST00000217957.10 |
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr2_-_88979016 | 2.50 |
ENST00000390247.2
|
IGKV3-7
|
immunoglobulin kappa variable 3-7 (non-functional) |
| chr1_+_198638457 | 2.50 |
ENST00000367379.6
|
PTPRC
|
protein tyrosine phosphatase receptor type C |
| chr1_+_198638723 | 2.48 |
ENST00000643513.1
|
PTPRC
|
protein tyrosine phosphatase receptor type C |
| chr12_-_9869345 | 2.47 |
ENST00000228438.3
|
CLEC2B
|
C-type lectin domain family 2 member B |
| chr14_+_22304051 | 2.46 |
ENST00000390466.1
|
TRAV39
|
T cell receptor alpha variable 39 |
| chr1_-_157777124 | 2.46 |
ENST00000361516.8
ENST00000368181.4 |
FCRL2
|
Fc receptor like 2 |
| chr1_-_169703329 | 2.42 |
ENST00000497295.1
|
SELL
|
selectin L |
| chr9_-_37025733 | 2.40 |
ENST00000651550.1
|
PAX5
|
paired box 5 |
| chr2_-_207167220 | 2.40 |
ENST00000421199.5
ENST00000457962.5 |
KLF7
|
Kruppel like factor 7 |
| chr15_-_55270874 | 2.39 |
ENST00000567380.5
ENST00000565972.5 ENST00000569493.5 |
RAB27A
|
RAB27A, member RAS oncogene family |
| chr4_-_142305826 | 2.39 |
ENST00000514525.1
|
INPP4B
|
inositol polyphosphate-4-phosphatase type II B |
| chr1_+_222737283 | 2.39 |
ENST00000360827.6
|
FAM177B
|
family with sequence similarity 177 member B |
| chr7_-_78771265 | 2.36 |
ENST00000630991.2
ENST00000629359.2 |
MAGI2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| chr9_+_122371036 | 2.36 |
ENST00000619306.5
ENST00000426608.6 ENST00000223423.8 |
PTGS1
|
prostaglandin-endoperoxide synthase 1 |
| chr1_-_68232514 | 2.34 |
ENST00000262348.9
ENST00000370973.2 ENST00000370971.1 |
WLS
|
Wnt ligand secretion mediator |
| chr17_-_10026265 | 2.34 |
ENST00000437099.6
ENST00000396115.6 |
GAS7
|
growth arrest specific 7 |
| chr15_-_55270280 | 2.31 |
ENST00000564609.5
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr10_-_102120246 | 2.28 |
ENST00000425280.2
|
LDB1
|
LIM domain binding 1 |
| chr18_-_55351977 | 2.26 |
ENST00000643689.1
|
TCF4
|
transcription factor 4 |
| chrX_+_123963164 | 2.26 |
ENST00000394478.1
|
STAG2
|
stromal antigen 2 |
| chr2_-_144521042 | 2.25 |
ENST00000637267.2
|
ZEB2
|
zinc finger E-box binding homeobox 2 |
| chr10_-_7410973 | 2.23 |
ENST00000684547.1
ENST00000673876.1 ENST00000397167.6 |
SFMBT2
|
Scm like with four mbt domains 2 |
| chr18_+_23992773 | 2.22 |
ENST00000304621.10
|
TTC39C
|
tetratricopeptide repeat domain 39C |
| chr13_+_77741160 | 2.21 |
ENST00000314070.9
ENST00000351546.7 |
SLAIN1
|
SLAIN motif family member 1 |
| chr1_-_68232539 | 2.19 |
ENST00000370976.7
ENST00000354777.6 |
WLS
|
Wnt ligand secretion mediator |
| chr5_-_141651376 | 2.17 |
ENST00000522783.5
ENST00000519800.1 ENST00000435817.7 |
FCHSD1
|
FCH and double SH3 domains 1 |
| chrX_+_108044967 | 2.13 |
ENST00000415430.7
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr9_+_79571956 | 2.13 |
ENST00000376552.8
|
TLE4
|
TLE family member 4, transcriptional corepressor |
| chr3_+_153162196 | 2.13 |
ENST00000323534.5
|
RAP2B
|
RAP2B, member of RAS oncogene family |
| chr1_+_198639162 | 2.12 |
ENST00000418674.1
|
PTPRC
|
protein tyrosine phosphatase receptor type C |
| chr12_-_31325494 | 2.08 |
ENST00000543615.1
|
SINHCAF
|
SIN3-HDAC complex associated factor |
| chr4_+_168497044 | 2.08 |
ENST00000505667.6
|
PALLD
|
palladin, cytoskeletal associated protein |
| chr4_+_40200320 | 2.07 |
ENST00000511121.5
|
RHOH
|
ras homolog family member H |
| chr10_+_92691813 | 2.07 |
ENST00000472590.6
|
HHEX
|
hematopoietically expressed homeobox |
| chr6_+_26365215 | 2.06 |
ENST00000527422.5
ENST00000356386.6 ENST00000396948.5 |
BTN3A2
|
butyrophilin subfamily 3 member A2 |
| chr14_+_22271921 | 2.06 |
ENST00000390464.2
|
TRAV38-1
|
T cell receptor alpha variable 38-1 |
| chr7_+_100119607 | 2.05 |
ENST00000262932.5
|
CNPY4
|
canopy FGF signaling regulator 4 |
| chr13_+_48256214 | 2.04 |
ENST00000650237.1
|
ITM2B
|
integral membrane protein 2B |
| chr12_+_28257195 | 2.03 |
ENST00000381259.5
|
CCDC91
|
coiled-coil domain containing 91 |
| chrX_+_136648214 | 2.03 |
ENST00000370628.2
|
CD40LG
|
CD40 ligand |
| chr8_-_42377227 | 2.02 |
ENST00000220812.3
|
DKK4
|
dickkopf WNT signaling pathway inhibitor 4 |
| chr6_+_26402289 | 2.01 |
ENST00000414912.2
|
BTN3A1
|
butyrophilin subfamily 3 member A1 |
| chr7_-_13986498 | 1.99 |
ENST00000420159.6
ENST00000399357.7 ENST00000403527.5 |
ETV1
|
ETS variant transcription factor 1 |
| chr7_+_37683733 | 1.98 |
ENST00000334425.2
ENST00000450180.5 |
GPR141
|
G protein-coupled receptor 141 |
| chr14_+_61187544 | 1.96 |
ENST00000555185.5
ENST00000557294.5 ENST00000556778.5 |
PRKCH
|
protein kinase C eta |
| chr12_+_53954870 | 1.96 |
ENST00000243103.4
|
HOXC12
|
homeobox C12 |
| chr20_+_43916142 | 1.95 |
ENST00000423191.6
ENST00000372999.5 |
TOX2
|
TOX high mobility group box family member 2 |
| chr10_-_102120318 | 1.95 |
ENST00000673968.1
|
LDB1
|
LIM domain binding 1 |
| chr12_+_9971512 | 1.95 |
ENST00000350667.4
|
CLEC12A
|
C-type lectin domain family 12 member A |
| chr7_-_78771058 | 1.94 |
ENST00000628781.1
|
MAGI2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| chr7_-_78771108 | 1.94 |
ENST00000626691.2
|
MAGI2
|
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| chr6_+_26365176 | 1.93 |
ENST00000377708.7
|
BTN3A2
|
butyrophilin subfamily 3 member A2 |
| chr3_-_112641128 | 1.93 |
ENST00000206423.8
|
CCDC80
|
coiled-coil domain containing 80 |
| chr12_+_8513499 | 1.93 |
ENST00000299665.3
|
CLEC4D
|
C-type lectin domain family 4 member D |
| chr6_+_26365159 | 1.92 |
ENST00000532865.5
ENST00000396934.7 ENST00000508906.6 ENST00000530653.5 ENST00000527417.5 |
BTN3A2
|
butyrophilin subfamily 3 member A2 |
| chr7_-_55552741 | 1.91 |
ENST00000418904.5
|
VOPP1
|
VOPP1 WW domain binding protein |
| chr3_-_112641292 | 1.91 |
ENST00000439685.6
|
CCDC80
|
coiled-coil domain containing 80 |
| chr15_+_85544036 | 1.90 |
ENST00000558166.2
|
AKAP13
|
A-kinase anchoring protein 13 |
| chr5_+_179732811 | 1.90 |
ENST00000292599.4
|
MAML1
|
mastermind like transcriptional coactivator 1 |
| chr12_-_31326111 | 1.88 |
ENST00000539409.5
|
SINHCAF
|
SIN3-HDAC complex associated factor |
| chr14_+_71586261 | 1.88 |
ENST00000358550.6
|
SIPA1L1
|
signal induced proliferation associated 1 like 1 |
| chr9_+_122370523 | 1.87 |
ENST00000643810.1
ENST00000540753.6 |
PTGS1
|
prostaglandin-endoperoxide synthase 1 |
| chr3_-_71306012 | 1.87 |
ENST00000649431.1
ENST00000610810.5 |
FOXP1
|
forkhead box P1 |
| chr6_-_36547400 | 1.84 |
ENST00000229812.8
|
STK38
|
serine/threonine kinase 38 |
| chr6_+_42746958 | 1.82 |
ENST00000614467.4
|
BICRAL
|
BRD4 interacting chromatin remodeling complex associated protein like |
| chr3_+_141387616 | 1.80 |
ENST00000509883.5
|
ZBTB38
|
zinc finger and BTB domain containing 38 |
| chr9_-_120877167 | 1.80 |
ENST00000373896.8
ENST00000312189.10 |
PHF19
|
PHD finger protein 19 |
| chr6_-_32190170 | 1.78 |
ENST00000375050.6
|
PBX2
|
PBX homeobox 2 |
| chr10_-_54801221 | 1.77 |
ENST00000644397.2
ENST00000395445.6 ENST00000613657.5 ENST00000320301.11 |
PCDH15
|
protocadherin related 15 |
| chr1_+_226063466 | 1.75 |
ENST00000666609.1
ENST00000661429.1 |
H3-3A
|
H3.3 histone A |
| chr12_-_31326142 | 1.72 |
ENST00000337682.9
|
SINHCAF
|
SIN3-HDAC complex associated factor |
| chr7_-_77798359 | 1.72 |
ENST00000257663.4
|
TMEM60
|
transmembrane protein 60 |
| chr4_+_168497066 | 1.68 |
ENST00000261509.10
|
PALLD
|
palladin, cytoskeletal associated protein |
| chr2_-_288759 | 1.66 |
ENST00000452023.1
|
ALKAL2
|
ALK and LTK ligand 2 |
| chr9_+_79572572 | 1.66 |
ENST00000435650.5
ENST00000414465.5 ENST00000376537.8 |
TLE4
|
TLE family member 4, transcriptional corepressor |
| chr3_+_111674654 | 1.65 |
ENST00000636933.1
ENST00000393934.7 ENST00000477665.2 |
PLCXD2
|
phosphatidylinositol specific phospholipase C X domain containing 2 |
| chr4_-_76007501 | 1.60 |
ENST00000264888.6
|
CXCL9
|
C-X-C motif chemokine ligand 9 |
| chr9_+_79572715 | 1.54 |
ENST00000265284.10
|
TLE4
|
TLE family member 4, transcriptional corepressor |
| chr12_-_10130082 | 1.54 |
ENST00000533022.5
|
CLEC7A
|
C-type lectin domain containing 7A |
| chr6_-_116545658 | 1.51 |
ENST00000368602.4
|
TRAPPC3L
|
trafficking protein particle complex 3 like |
| chr5_-_88823763 | 1.50 |
ENST00000635898.1
ENST00000626391.2 ENST00000628656.2 |
MEF2C
|
myocyte enhancer factor 2C |
| chr14_+_22202561 | 1.50 |
ENST00000390460.1
|
TRAV26-2
|
T cell receptor alpha variable 26-2 |
| chr19_+_49513154 | 1.48 |
ENST00000426395.7
ENST00000600273.5 ENST00000599988.5 |
FCGRT
|
Fc fragment of IgG receptor and transporter |
| chr1_-_152159227 | 1.46 |
ENST00000316073.3
|
RPTN
|
repetin |
| chr3_+_15003912 | 1.46 |
ENST00000406272.6
ENST00000617312.4 |
NR2C2
|
nuclear receptor subfamily 2 group C member 2 |
| chr14_+_58634055 | 1.45 |
ENST00000556859.5
ENST00000421793.5 |
DACT1
|
dishevelled binding antagonist of beta catenin 1 |
| chr20_+_43667105 | 1.44 |
ENST00000217026.5
|
MYBL2
|
MYB proto-oncogene like 2 |
| chr3_-_52056552 | 1.44 |
ENST00000495880.2
|
DUSP7
|
dual specificity phosphatase 7 |
| chr14_-_77616630 | 1.42 |
ENST00000216484.7
|
SPTLC2
|
serine palmitoyltransferase long chain base subunit 2 |
| chr2_-_144517663 | 1.41 |
ENST00000427902.5
ENST00000462355.2 ENST00000470879.5 ENST00000409487.7 ENST00000435831.5 ENST00000630572.2 |
ZEB2
|
zinc finger E-box binding homeobox 2 |
| chr3_+_157436842 | 1.39 |
ENST00000295927.4
|
PTX3
|
pentraxin 3 |
| chr17_-_73227700 | 1.39 |
ENST00000579872.1
ENST00000580032.1 |
FAM104A
|
family with sequence similarity 104 member A |
| chr13_+_77535742 | 1.38 |
ENST00000377246.7
|
SCEL
|
sciellin |
| chr9_+_2159850 | 1.37 |
ENST00000416751.2
|
SMARCA2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| chr2_+_157257687 | 1.36 |
ENST00000259056.5
|
GALNT5
|
polypeptide N-acetylgalactosaminyltransferase 5 |
| chr13_+_108629605 | 1.36 |
ENST00000457511.7
|
MYO16
|
myosin XVI |
| chr6_-_129710145 | 1.36 |
ENST00000368149.3
|
ARHGAP18
|
Rho GTPase activating protein 18 |
| chr8_+_32614361 | 1.34 |
ENST00000522569.1
|
NRG1
|
neuregulin 1 |
| chrX_+_22136552 | 1.33 |
ENST00000682888.1
ENST00000684356.1 |
PHEX
|
phosphate regulating endopeptidase homolog X-linked |
| chr13_+_77535681 | 1.32 |
ENST00000349847.4
|
SCEL
|
sciellin |
| chr3_-_158106408 | 1.32 |
ENST00000483851.7
|
SHOX2
|
short stature homeobox 2 |
| chr8_+_38974212 | 1.32 |
ENST00000302495.5
|
HTRA4
|
HtrA serine peptidase 4 |
| chr5_+_134526176 | 1.32 |
ENST00000681820.1
ENST00000512386.6 ENST00000612830.2 |
JADE2
|
jade family PHD finger 2 |
| chr9_+_79573162 | 1.31 |
ENST00000425506.5
|
TLE4
|
TLE family member 4, transcriptional corepressor |
| chr13_+_77535669 | 1.30 |
ENST00000535157.5
|
SCEL
|
sciellin |
| chrX_+_78747705 | 1.29 |
ENST00000614823.5
ENST00000435339.3 ENST00000514744.5 |
LPAR4
|
lysophosphatidic acid receptor 4 |
| chr15_-_55270249 | 1.29 |
ENST00000568803.1
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr1_+_180632001 | 1.25 |
ENST00000367590.9
ENST00000367589.3 |
XPR1
|
xenotropic and polytropic retrovirus receptor 1 |
| chr4_+_26322850 | 1.25 |
ENST00000514675.5
|
RBPJ
|
recombination signal binding protein for immunoglobulin kappa J region |
| chr2_-_223602284 | 1.25 |
ENST00000421386.1
ENST00000305409.3 ENST00000433889.1 |
SCG2
|
secretogranin II |
| chr3_-_108529322 | 1.25 |
ENST00000273353.4
|
MYH15
|
myosin heavy chain 15 |
| chr9_-_16728165 | 1.24 |
ENST00000603713.5
ENST00000603313.5 |
BNC2
|
basonuclin 2 |
| chr11_+_33039996 | 1.23 |
ENST00000432887.5
ENST00000528898.1 ENST00000531632.6 |
TCP11L1
|
t-complex 11 like 1 |
| chr6_-_161274010 | 1.23 |
ENST00000366911.9
ENST00000366905.3 |
AGPAT4
|
1-acylglycerol-3-phosphate O-acyltransferase 4 |
| chr17_-_40755328 | 1.22 |
ENST00000312150.5
|
KRT25
|
keratin 25 |
| chr19_-_51804104 | 1.22 |
ENST00000594900.1
|
FPR1
|
formyl peptide receptor 1 |
| chr11_-_108222594 | 1.20 |
ENST00000278612.9
|
NPAT
|
nuclear protein, coactivator of histone transcription |
| chr14_-_53958757 | 1.20 |
ENST00000559642.1
|
BMP4
|
bone morphogenetic protein 4 |
| chr3_-_157503574 | 1.20 |
ENST00000494677.5
ENST00000468233.5 |
VEPH1
|
ventricular zone expressed PH domain containing 1 |
| chr10_-_49188380 | 1.20 |
ENST00000374153.7
ENST00000374148.1 ENST00000374151.7 |
TMEM273
|
transmembrane protein 273 |
| chr12_-_31326171 | 1.19 |
ENST00000542983.1
|
SINHCAF
|
SIN3-HDAC complex associated factor |
| chr2_+_17816458 | 1.19 |
ENST00000281047.4
|
MSGN1
|
mesogenin 1 |
| chr11_-_117876612 | 1.18 |
ENST00000584230.1
ENST00000526014.6 ENST00000584394.5 ENST00000614497.5 ENST00000532984.1 |
FXYD6
FXYD6-FXYD2
|
FXYD domain containing ion transport regulator 6 FXYD6-FXYD2 readthrough |
| chr17_+_59155726 | 1.18 |
ENST00000578777.5
ENST00000577457.1 ENST00000582995.5 ENST00000262293.9 ENST00000614081.1 |
PRR11
|
proline rich 11 |
| chr12_-_56741535 | 1.18 |
ENST00000647707.1
|
ENSG00000285625.1
|
novel protein |
| chr6_+_29550407 | 1.17 |
ENST00000641137.1
|
OR2I1P
|
olfactory receptor family 2 subfamily I member 1 pseudogene |
| chr6_+_26440472 | 1.16 |
ENST00000494393.5
ENST00000482451.5 ENST00000471353.5 ENST00000361232.7 ENST00000487627.5 ENST00000496719.1 ENST00000244519.7 ENST00000490254.5 ENST00000487272.1 |
BTN3A3
|
butyrophilin subfamily 3 member A3 |
| chr18_-_63158208 | 1.16 |
ENST00000678301.1
|
BCL2
|
BCL2 apoptosis regulator |
Network of associatons between targets according to the STRING database.
First level regulatory network of SHOX
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 11.2 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
| 2.7 | 8.0 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 2.2 | 11.0 | GO:2000471 | regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473) |
| 1.8 | 9.1 | GO:1904823 | pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 1.7 | 8.4 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 1.5 | 4.6 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 1.4 | 4.3 | GO:0060730 | regulation of intestinal epithelial structure maintenance(GO:0060730) |
| 1.4 | 4.2 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 1.4 | 4.1 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 1.2 | 8.7 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 1.2 | 3.5 | GO:0002304 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
| 1.1 | 4.5 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 1.1 | 3.4 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 1.0 | 3.0 | GO:0032761 | negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017) |
| 0.9 | 2.6 | GO:0061011 | hepatic duct development(GO:0061011) hepatoblast differentiation(GO:0061017) |
| 0.9 | 4.3 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.7 | 5.7 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.7 | 3.4 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.5 | 6.9 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.5 | 1.5 | GO:0000354 | cis assembly of pre-catalytic spliceosome(GO:0000354) |
| 0.5 | 1.5 | GO:1904864 | regulation of beta-catenin-TCF complex assembly(GO:1904863) negative regulation of beta-catenin-TCF complex assembly(GO:1904864) |
| 0.5 | 12.6 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.5 | 1.9 | GO:0060922 | cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928) |
| 0.5 | 1.4 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.5 | 0.9 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.5 | 1.4 | GO:1903015 | regulation of exo-alpha-sialidase activity(GO:1903015) |
| 0.4 | 3.1 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
| 0.4 | 5.0 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.4 | 1.2 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 0.4 | 7.2 | GO:0003402 | planar cell polarity pathway involved in axis elongation(GO:0003402) |
| 0.4 | 9.4 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.3 | 2.0 | GO:0051799 | negative regulation of hair follicle development(GO:0051799) |
| 0.3 | 1.0 | GO:0021524 | visceral motor neuron differentiation(GO:0021524) |
| 0.3 | 2.5 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.3 | 6.9 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.3 | 1.6 | GO:0072096 | apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 0.3 | 7.7 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.3 | 1.2 | GO:0050883 | musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.3 | 2.6 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.3 | 1.7 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.3 | 1.7 | GO:0070378 | positive regulation of ERK5 cascade(GO:0070378) |
| 0.3 | 1.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.3 | 2.7 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.3 | 10.5 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.3 | 5.8 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.3 | 2.9 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.2 | 1.0 | GO:0035470 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of vascular wound healing(GO:0035470) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
| 0.2 | 4.4 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
| 0.2 | 1.2 | GO:0032848 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 0.2 | 0.2 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.2 | 0.2 | GO:1900135 | positive regulation of renin secretion into blood stream(GO:1900135) |
| 0.2 | 1.9 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.2 | 1.5 | GO:0021776 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
| 0.2 | 4.6 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.2 | 0.6 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 0.2 | 0.6 | GO:1903224 | regulation of endodermal cell differentiation(GO:1903224) |
| 0.2 | 2.5 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.2 | 1.1 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.2 | 8.8 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.2 | 2.7 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.2 | 3.1 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.2 | 2.8 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.2 | 0.6 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.2 | 1.1 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 0.3 | GO:0010041 | response to iron(III) ion(GO:0010041) |
| 0.2 | 2.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.2 | 2.0 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.2 | 2.0 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.2 | 1.1 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.2 | 0.5 | GO:0060466 | CD24 biosynthetic process(GO:0035724) activation of meiosis involved in egg activation(GO:0060466) negative regulation of monocyte extravasation(GO:2000438) regulation of CD24 biosynthetic process(GO:2000559) positive regulation of CD24 biosynthetic process(GO:2000560) |
| 0.2 | 0.8 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.1 | 2.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 0.8 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 2.3 | GO:0038129 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129) |
| 0.1 | 0.8 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.1 | 3.6 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.1 | 2.0 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 14.8 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 0.5 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) |
| 0.1 | 0.5 | GO:0046379 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
| 0.1 | 0.8 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 1.3 | GO:1901297 | positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.1 | 1.1 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.1 | 3.0 | GO:0042789 | mRNA transcription from RNA polymerase II promoter(GO:0042789) |
| 0.1 | 0.8 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.1 | 2.2 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 0.3 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.1 | 0.5 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.1 | 5.0 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.1 | 1.6 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.1 | 24.0 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.1 | 1.1 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.1 | 3.3 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 1.3 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 0.1 | 1.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 0.5 | GO:0021836 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925) |
| 0.1 | 1.2 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.1 | 0.3 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.1 | 6.6 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 0.2 | GO:1904397 | retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
| 0.1 | 2.1 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 1.5 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.1 | 0.5 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) post-embryonic organ morphogenesis(GO:0048563) |
| 0.1 | 1.2 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.1 | 0.9 | GO:1902101 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 0.1 | 1.0 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.1 | 0.4 | GO:0010159 | specification of organ position(GO:0010159) |
| 0.1 | 1.8 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 0.3 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.1 | 1.1 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 1.9 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.1 | 0.3 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 0.1 | 0.5 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.1 | 1.5 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 0.4 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.1 | 2.0 | GO:0048730 | epidermis morphogenesis(GO:0048730) |
| 0.1 | 0.7 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.1 | 1.7 | GO:0030728 | ovulation(GO:0030728) |
| 0.1 | 0.5 | GO:0009253 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.1 | 0.5 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.1 | 1.4 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.1 | 0.4 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 0.1 | 1.2 | GO:0007379 | segment specification(GO:0007379) |
| 0.1 | 4.3 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
| 0.1 | 0.5 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 1.2 | GO:0043586 | tongue development(GO:0043586) |
| 0.0 | 1.2 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.0 | 0.1 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.0 | 0.7 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.9 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.5 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.0 | 0.2 | GO:0033320 | UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320) |
| 0.0 | 0.3 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.0 | 0.2 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.0 | 0.4 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 0.0 | 0.9 | GO:0086069 | bundle of His cell to Purkinje myocyte communication(GO:0086069) |
| 0.0 | 0.2 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.0 | 0.4 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.0 | 0.7 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) |
| 0.0 | 0.8 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.2 | GO:0036367 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
| 0.0 | 5.1 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 1.1 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.0 | 0.3 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 0.8 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.0 | 1.0 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 1.4 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 1.8 | GO:0033198 | response to ATP(GO:0033198) |
| 0.0 | 0.3 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.0 | 1.5 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 3.0 | GO:0043407 | negative regulation of MAP kinase activity(GO:0043407) |
| 0.0 | 0.8 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.0 | 0.2 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.0 | 0.5 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.0 | 0.2 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.0 | 2.1 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 0.2 | GO:0021764 | amygdala development(GO:0021764) |
| 0.0 | 0.9 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 0.1 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 1.9 | GO:0002292 | T cell differentiation involved in immune response(GO:0002292) |
| 0.0 | 5.2 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.0 | 1.3 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.0 | 0.1 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.0 | 0.8 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 2.1 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 0.0 | 0.1 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.0 | 0.3 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.0 | 0.7 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 1.1 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.0 | 1.1 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 1.9 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 1.4 | GO:0043525 | positive regulation of neuron apoptotic process(GO:0043525) |
| 0.0 | 3.0 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.0 | 0.5 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.0 | 0.3 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.0 | 0.5 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.0 | 0.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.0 | 1.0 | GO:0002763 | positive regulation of myeloid leukocyte differentiation(GO:0002763) |
| 0.0 | 0.6 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.0 | 0.1 | GO:0030187 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 0.0 | 10.5 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 0.4 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 1.1 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.0 | 0.1 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.0 | 0.2 | GO:0070487 | monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.0 | 0.6 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 1.0 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.8 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.3 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 1.0 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 1.4 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.7 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) |
| 0.0 | 0.3 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.0 | 3.7 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 1.2 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 2.8 | GO:0006275 | regulation of DNA replication(GO:0006275) |
| 0.0 | 0.1 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.0 | 0.5 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.0 | 1.9 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.2 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
| 0.0 | 0.2 | GO:0005513 | detection of calcium ion(GO:0005513) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 8.0 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 1.1 | 3.3 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.7 | 4.8 | GO:0031523 | Myb complex(GO:0031523) |
| 0.5 | 8.9 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.5 | 5.0 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.4 | 1.2 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.4 | 1.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.3 | 12.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.3 | 6.2 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.3 | 0.9 | GO:0060187 | cell pole(GO:0060187) |
| 0.2 | 3.2 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.2 | 2.7 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 4.0 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.2 | 4.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 0.7 | GO:0035101 | FACT complex(GO:0035101) |
| 0.2 | 0.5 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.1 | 0.6 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.1 | 1.1 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 15.5 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 1.9 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 1.2 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.1 | 0.4 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 0.1 | 3.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 1.5 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 2.5 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.1 | 0.4 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.1 | 4.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 2.6 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 2.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.0 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 5.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.3 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
| 0.1 | 0.8 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.1 | 0.9 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 5.1 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 0.4 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
| 0.1 | 2.1 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 1.2 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 0.5 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 1.0 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 3.9 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.8 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 1.5 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 0.9 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 1.5 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.7 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 1.1 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.9 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 0.7 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 2.8 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.0 | 6.0 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 0.7 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.3 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 0.0 | 15.8 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 2.1 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.8 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 1.5 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 4.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.1 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.0 | 3.4 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 0.2 | GO:0070083 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.0 | 0.6 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 0.6 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.0 | 5.3 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.1 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 1.8 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.2 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 0.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 4.1 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.5 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 1.1 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 6.7 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 0.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 1.0 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.7 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.7 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 2.5 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.3 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 4.4 | GO:0030139 | endocytic vesicle(GO:0030139) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 9.1 | GO:0005350 | pyrimidine nucleobase transmembrane transporter activity(GO:0005350) |
| 1.4 | 6.9 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 1.2 | 4.6 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.8 | 5.1 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.7 | 2.0 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 0.6 | 1.3 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.6 | 7.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.5 | 9.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.4 | 1.9 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.4 | 1.1 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.4 | 3.4 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.4 | 5.0 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.4 | 7.2 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.3 | 2.7 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.3 | 1.6 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.3 | 12.6 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.3 | 4.2 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.3 | 11.0 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 1.7 | GO:0030298 | receptor signaling protein tyrosine kinase activator activity(GO:0030298) |
| 0.2 | 0.7 | GO:0032093 | SAM domain binding(GO:0032093) |
| 0.2 | 1.1 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 0.2 | 7.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 2.0 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.2 | 0.6 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.2 | 10.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.2 | 2.6 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.2 | 1.8 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.2 | 1.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.2 | 4.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 1.2 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.2 | 4.3 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.2 | 5.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.2 | 15.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.2 | 1.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.7 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.1 | 1.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.1 | 1.8 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.1 | 0.5 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 4.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 4.1 | GO:0023023 | MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026) |
| 0.1 | 1.5 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 0.3 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.1 | 1.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 0.3 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682) |
| 0.1 | 1.6 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.1 | 2.3 | GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity(GO:0030297) |
| 0.1 | 0.9 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.1 | 1.0 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 1.4 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 0.5 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.1 | 0.7 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.1 | 2.8 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 21.1 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 3.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 0.9 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.1 | 6.8 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 1.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 0.2 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.1 | 6.7 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 1.0 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 5.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 0.6 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.1 | 2.1 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.1 | 0.6 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.1 | 0.5 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 0.3 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.1 | 2.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 8.6 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.1 | 3.4 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.9 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.1 | 1.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.5 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
| 0.1 | 1.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 2.6 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 2.9 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 3.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 1.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 3.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 1.2 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.0 | 0.2 | GO:0048040 | UDP-glucuronate decarboxylase activity(GO:0048040) |
| 0.0 | 0.2 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 0.0 | 1.3 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 1.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.5 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 1.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.0 | 1.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 2.3 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.5 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.0 | 0.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.2 | GO:0008955 | peptidoglycan glycosyltransferase activity(GO:0008955) |
| 0.0 | 1.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 0.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.0 | 0.5 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.8 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 1.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 3.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 2.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 7.7 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 0.5 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.0 | 1.8 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 1.3 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.1 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.0 | 3.1 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.1 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
| 0.0 | 0.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 11.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.7 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 2.0 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.8 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.9 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 5.2 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 0.1 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.0 | 0.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.0 | 0.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 2.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.5 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 0.1 | GO:0030345 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.0 | 0.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 0.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.4 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.0 | 2.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.8 | GO:0016878 | acid-thiol ligase activity(GO:0016878) |
| 0.0 | 1.2 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.1 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.0 | 0.3 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 5.4 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 1.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.2 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.7 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.2 | 19.7 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.2 | 12.4 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 3.4 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 7.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 5.6 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 5.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 5.7 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 1.2 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 19.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.7 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 2.5 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.1 | 2.7 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 2.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 1.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 2.0 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 1.7 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.8 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 3.7 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.9 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 5.0 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 2.4 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 1.0 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 3.1 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 3.9 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 2.8 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 2.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.0 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 3.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 3.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.9 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 0.5 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 8.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 1.3 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 0.5 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.4 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.6 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.7 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 8.0 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.6 | 16.7 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.5 | 9.1 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.4 | 9.8 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.3 | 8.7 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.3 | 3.8 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.2 | 5.1 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.2 | 5.0 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 3.0 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.1 | 7.1 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 3.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 5.0 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 3.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 2.3 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 1.1 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 7.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 3.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 19.0 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 2.1 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 0.8 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 1.9 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 1.3 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 2.3 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 5.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.8 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.0 | 1.9 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 1.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 1.8 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 0.7 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 1.9 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 5.0 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 2.0 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.0 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 1.3 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.5 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.8 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 1.1 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.5 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 1.1 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.0 | 1.5 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.7 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 0.9 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 1.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.3 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 2.4 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.6 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.7 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 1.1 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 2.0 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.6 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |