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Illumina Body Map 2 (GSE30611)

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Results for SIX5_SMARCC2_HCFC1

Z-value: 2.70

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
ENSG00000177045.10 SIX homeobox 5
ENSG00000139613.12 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
ENSG00000172534.14 host cell factor C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMARCC2hg38_v1_chr12_-_56189548_561896090.568.1e-04Click!
HCFC1hg38_v1_chrX_-_153971810_1539718440.173.6e-01Click!
SIX5hg38_v1_chr19_-_45768627_457687450.115.6e-01Click!

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_4791710 7.95 ENST00000269856.5
fem-1 homolog A
chr4_-_8158689 5.89 ENST00000505872.5
ENST00000341937.9
ENST00000361581.9
ENST00000407564.7
ENST00000361737.9
ENST00000447017.7
ENST00000428004.6
actin binding LIM protein family member 2
chr5_-_146182591 4.23 ENST00000510191.5
ENST00000674277.1
ENST00000674447.1
ENST00000674270.1
ENST00000394434.7
ENST00000674290.1
ENST00000674398.1
ENST00000674174.1
leucyl-tRNA synthetase 1
chr17_+_7455571 3.96 ENST00000575379.1
cholinergic receptor nicotinic beta 1 subunit
chr5_-_146182475 3.93 ENST00000674158.1
ENST00000674191.1
ENST00000274562.13
leucyl-tRNA synthetase 1
chr7_+_93232340 3.74 ENST00000251739.9
ENST00000544910.5
ENST00000305866.10
ENST00000458530.1
VPS50 subunit of EARP/GARPII complex
chr1_-_156741124 3.71 ENST00000368211.8
mitochondrial ribosomal protein L24
chr12_+_6852115 3.63 ENST00000389231.9
ENST00000229268.13
ENST00000542087.1
ubiquitin specific peptidase 5
chr9_+_131289685 3.62 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr12_+_106774630 3.42 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr11_-_73598183 3.38 ENST00000064778.8
family with sequence similarity 168 member A
chr19_-_38899710 3.33 ENST00000447739.1
ENST00000407552.5
sirtuin 2
chr19_+_34734155 3.27 ENST00000599244.5
ENST00000392232.7
ENST00000492450.3
ENST00000595708.5
ENST00000593781.5
zinc finger protein 181
chr19_-_38899800 3.21 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr12_+_120302316 3.17 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr3_+_69739425 3.13 ENST00000352241.9
ENST00000642352.1
melanocyte inducing transcription factor
chr3_-_184017863 3.07 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr17_+_69414690 3.06 ENST00000590474.7
mitogen-activated protein kinase kinase 6
chr11_-_73598067 3.06 ENST00000450446.6
ENST00000356467.5
family with sequence similarity 168 member A
chr19_-_38899529 3.04 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr1_-_2526585 2.88 ENST00000378466.9
ENST00000435556.8
pantothenate kinase 4 (inactive)
chr19_-_44356664 2.79 ENST00000354340.9
ENST00000337401.8
ENST00000587909.1
zinc finger protein 112
chr4_-_151760977 2.71 ENST00000512306.5
ENST00000508611.1
ENST00000515812.5
ENST00000263985.11
glutamyl-tRNA amidotransferase subunit B
chr1_-_156741067 2.71 ENST00000361531.6
ENST00000412846.5
mitochondrial ribosomal protein L24
chr20_-_23421409 2.69 ENST00000377026.4
ENST00000398425.7
ENST00000432543.6
ENST00000617876.4
NSF attachment protein beta
chr14_-_77320855 2.69 ENST00000556394.2
ENST00000261534.9
protein O-mannosyltransferase 2
chr8_-_28889909 2.67 ENST00000523436.5
ENST00000521777.5
ENST00000520184.1
integrator complex subunit 9
chr9_-_135961310 2.66 ENST00000371756.4
UBA domain containing 1
chr7_+_74964692 2.65 ENST00000616305.2
cytosolic arginine sensor for mTORC1 subunit 2
chr1_+_43946905 2.54 ENST00000372343.8
importin 13
chr2_+_216412414 2.53 ENST00000430374.5
ENST00000357276.9
ENST00000444508.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1
chr20_+_64063105 2.52 ENST00000395053.7
ENST00000343484.10
ENST00000339217.8
transcription elongation factor A2
chr10_+_101354083 2.50 ENST00000408038.6
ENST00000370187.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr10_+_101354028 2.47 ENST00000393441.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr12_-_53727476 2.47 ENST00000549784.5
ENST00000262059.8
calcium binding and coiled-coil domain 1
chr2_-_241508318 2.45 ENST00000439101.5
ENST00000424537.5
ENST00000401869.5
ENST00000436402.5
serine/threonine kinase 25
chr2_+_171687784 2.44 ENST00000435234.5
ENST00000443458.5
ENST00000412370.5
dynein cytoplasmic 1 intermediate chain 2
chr7_-_76358982 2.42 ENST00000307630.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
chr1_-_185156903 2.41 ENST00000367506.10
tRNA methyltransferase 1 like
chr16_+_46884675 2.41 ENST00000562132.5
ENST00000440783.2
glutamic--pyruvic transaminase 2
chr2_+_171687457 2.35 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr2_+_171687501 2.32 ENST00000508530.5
dynein cytoplasmic 1 intermediate chain 2
chr3_-_45995807 2.31 ENST00000535325.5
ENST00000296137.7
FYVE and coiled-coil domain autophagy adaptor 1
chr11_-_72080472 2.28 ENST00000537217.5
ENST00000366394.7
ENST00000358965.10
ENST00000546131.1
ENST00000393695.8
ENST00000543937.5
ENST00000368959.9
ENST00000541641.5
nuclear mitotic apparatus protein 1
chr12_-_53727428 2.26 ENST00000548263.5
ENST00000430117.6
ENST00000549173.5
ENST00000550804.6
ENST00000551900.5
ENST00000546619.5
ENST00000548177.5
ENST00000549349.5
calcium binding and coiled-coil domain 1
chr14_-_77457554 2.25 ENST00000343765.6
ENST00000327028.8
ENST00000556412.4
ENST00000557466.1
ENST00000448935.6
ENST00000557658.6
ENST00000553888.5
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr17_+_43171187 2.22 ENST00000542611.5
ENST00000590996.6
ENST00000589872.1
NBR1 autophagy cargo receptor
chr7_-_151227035 2.21 ENST00000441774.1
ENST00000287844.7
ENST00000222388.6
ATP binding cassette subfamily F member 2
ABCF2-H2BE1 readthrough
chr2_-_241508568 2.20 ENST00000426941.1
ENST00000316586.9
ENST00000405585.5
ENST00000420551.1
ENST00000429279.5
ENST00000442307.5
serine/threonine kinase 25
chr9_+_131289807 2.20 ENST00000372261.1
phospholipid phosphatase 7 (inactive)
chr5_-_139439488 2.17 ENST00000302060.10
DnaJ heat shock protein family (Hsp40) member C18
chr14_-_77320741 2.13 ENST00000682795.1
ENST00000682247.1
protein O-mannosyltransferase 2
chr3_-_43106057 2.11 ENST00000344697.3
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr2_-_241508547 2.10 ENST00000405883.7
serine/threonine kinase 25
chr7_-_151057880 2.05 ENST00000485972.6
cyclin dependent kinase 5
chr3_-_43105939 2.03 ENST00000441964.1
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr7_-_151057848 2.03 ENST00000297518.4
cyclin dependent kinase 5
chr7_-_133082032 2.02 ENST00000448878.6
ENST00000262570.10
coiled-coil-helix-coiled-coil-helix domain containing 3
chr13_-_41132728 2.02 ENST00000379485.2
kelch repeat and BTB domain containing 6
chr10_+_38094327 2.00 ENST00000638053.1
ENST00000351773.7
ENST00000361085.9
zinc finger protein 37A
chr1_+_202348727 2.00 ENST00000356764.6
protein phosphatase 1 regulatory subunit 12B
chr2_+_171687409 1.99 ENST00000452242.5
ENST00000340296.8
dynein cytoplasmic 1 intermediate chain 2
chr11_-_72080389 1.98 ENST00000351960.10
ENST00000541719.5
ENST00000535111.5
nuclear mitotic apparatus protein 1
chr5_+_179060356 1.97 ENST00000315475.7
zinc finger protein 354C
chr1_+_1615478 1.96 ENST00000355826.10
ENST00000505820.7
ENST00000518681.6
ENST00000520777.6
MIB E3 ubiquitin protein ligase 2
chr19_+_40191410 1.96 ENST00000253055.8
mitogen-activated protein kinase kinase kinase 10
chr16_+_46884323 1.95 ENST00000340124.9
glutamic--pyruvic transaminase 2
chr19_+_35748549 1.93 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr2_-_241508630 1.93 ENST00000403346.7
ENST00000535007.5
serine/threonine kinase 25
chr8_+_17922974 1.92 ENST00000517730.5
ENST00000518537.5
ENST00000523055.5
ENST00000519253.5
pericentriolar material 1
chr19_+_44052005 1.92 ENST00000434772.8
ENST00000585552.5
zinc finger protein 223
chr2_+_171687672 1.91 ENST00000409197.5
ENST00000456808.5
ENST00000409317.5
ENST00000409773.5
ENST00000411953.5
ENST00000409453.5
dynein cytoplasmic 1 intermediate chain 2
chr13_-_41194485 1.91 ENST00000379483.4
kelch repeat and BTB domain containing 7
chr11_-_113773668 1.90 ENST00000200135.8
zw10 kinetochore protein
chr13_-_41263484 1.90 ENST00000379477.5
ENST00000452359.5
ENST00000379480.9
ENST00000430347.3
mitochondrial translation release factor 1
chr10_-_102502702 1.90 ENST00000369905.9
actin related protein 1A
chr11_+_73647549 1.89 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr20_-_25696831 1.88 ENST00000252979.6
zinc finger protein 337
chr1_+_202348687 1.86 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr10_-_102502669 1.86 ENST00000487599.1
actin related protein 1A
chr11_-_72080680 1.86 ENST00000613205.4
nuclear mitotic apparatus protein 1
chr8_+_17922837 1.85 ENST00000325083.12
pericentriolar material 1
chr1_-_154870264 1.84 ENST00000618040.4
ENST00000271915.9
potassium calcium-activated channel subfamily N member 3
chr20_+_57391388 1.83 ENST00000356208.10
ENST00000440234.6
RNA binding motif protein 38
chr3_+_32106612 1.83 ENST00000282541.10
ENST00000425459.5
ENST00000431009.1
glycerol-3-phosphate dehydrogenase 1 like
chr16_+_2048002 1.82 ENST00000646388.1
ENST00000439673.6
ENST00000350773.9
ENST00000642206.1
ENST00000644329.1
ENST00000644043.1
ENST00000642797.1
ENST00000642561.1
TSC complex subunit 2
chr12_+_56152439 1.80 ENST00000550443.5
myosin light chain 6B
chr17_+_43170452 1.77 ENST00000341165.10
ENST00000586650.5
NBR1 autophagy cargo receptor
chr13_-_113490683 1.74 ENST00000332592.7
ENST00000439909.2
ENST00000478244.6
defective in cullin neddylation 1 domain containing 2
chr3_+_101724602 1.74 ENST00000341893.8
centrosomal protein 97
chr13_-_32538683 1.74 ENST00000674456.1
ENST00000504114.5
NEDD4 binding protein 2 like 2
chr20_+_18288477 1.71 ENST00000377671.7
ENST00000360010.9
ENST00000628216.2
ENST00000425686.3
ENST00000434018.5
ENST00000630056.1
zinc finger protein 133
chr19_+_37078411 1.71 ENST00000337995.4
ENST00000304239.11
ENST00000589245.5
zinc finger protein 420
chr1_+_151612001 1.70 ENST00000642376.1
ENST00000368843.8
ENST00000458013.7
sorting nexin 27
chr16_+_56451513 1.70 ENST00000562150.5
ENST00000561646.5
ENST00000566157.6
ENST00000568397.1
2-oxoglutarate and iron dependent oxygenase domain containing 1
chr9_-_109119915 1.70 ENST00000374586.8
transmembrane protein 245
chr8_-_28889958 1.67 ENST00000521022.6
integrator complex subunit 9
chr10_+_58334976 1.67 ENST00000615793.1
ubiquitin conjugating enzyme E2 D1
chr14_+_35826298 1.66 ENST00000216807.12
BRMS1 like transcriptional repressor
chr15_+_90352239 1.65 ENST00000354377.8
ENST00000379090.9
zinc finger protein 774
chr18_+_74148508 1.64 ENST00000580087.5
ENST00000169551.11
translocase of inner mitochondrial membrane 21
chr10_-_37976589 1.64 ENST00000302609.8
zinc finger protein 25
chr10_+_58334998 1.63 ENST00000373910.9
ubiquitin conjugating enzyme E2 D1
chr14_+_101964561 1.62 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
dynein cytoplasmic 1 heavy chain 1
chr4_-_185425941 1.61 ENST00000264689.11
ENST00000505357.1
UFM1 specific peptidase 2
chr16_+_2047970 1.61 ENST00000643088.1
ENST00000643946.1
ENST00000382538.10
ENST00000219476.9
ENST00000642936.1
ENST00000401874.7
ENST00000644335.1
TSC complex subunit 2
chr16_+_25111703 1.60 ENST00000380966.8
ENST00000399069.8
leucine carboxyl methyltransferase 1
chr1_-_151165847 1.59 ENST00000368908.10
ENST00000440902.2
LysM domain containing 1
chr9_+_66900725 1.59 ENST00000621410.5
ENST00000621015.4
ENST00000616544.4
ENST00000612867.4
ENST00000619435.1
zinc finger protein 658
chr4_-_47914596 1.58 ENST00000381538.7
ENST00000329043.7
nuclear transcription factor, X-box binding like 1
chr16_-_4538819 1.58 ENST00000564828.5
cell death inducing p53 target 1
chr12_-_132956280 1.58 ENST00000536932.5
ENST00000360187.9
ENST00000392321.3
checkpoint with forkhead and ring finger domains
zinc finger protein 605
chr16_+_1959499 1.57 ENST00000268668.11
ENST00000543683.6
ENST00000569148.1
ENST00000570172.1
NADH:ubiquinone oxidoreductase subunit B10
chr3_+_159273235 1.57 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr5_+_5422665 1.56 ENST00000296564.9
interactor of little elongation complex ELL subunit 1
chr17_+_45161864 1.55 ENST00000589230.6
ENST00000591576.5
ENST00000591070.6
ENST00000592695.1
HEXIM P-TEFb complex subunit 2
chr3_+_167735238 1.55 ENST00000472941.5
serpin family I member 1
chr6_-_162727748 1.54 ENST00000366892.5
ENST00000366898.6
ENST00000366897.5
ENST00000366896.5
ENST00000674250.1
parkin RBR E3 ubiquitin protein ligase
chr2_+_63589135 1.53 ENST00000432309.6
malate dehydrogenase 1
chr5_-_40755885 1.53 ENST00000636863.1
ENST00000637375.1
ENST00000337702.5
ENST00000636106.1
tetratricopeptide repeat domain 33
chr19_-_40056156 1.53 ENST00000598845.5
ENST00000593605.1
ENST00000221355.10
ENST00000434248.6
zinc finger protein 780B
chr1_+_148952120 1.52 ENST00000313431.13
phosphodiesterase 4D interacting protein
chr16_-_4538761 1.51 ENST00000567695.6
ENST00000562334.5
ENST00000562579.5
ENST00000563507.5
cell death inducing p53 target 1
chr19_+_37371152 1.51 ENST00000483919.5
ENST00000588911.5
ENST00000587349.1
zinc finger protein 527
chr11_-_64166102 1.49 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr14_-_77320813 1.48 ENST00000682467.1
protein O-mannosyltransferase 2
chr1_+_38012706 1.48 ENST00000373014.5
UTP11 small subunit processome component
chr10_-_43574555 1.47 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
zinc finger protein 239
chr8_+_144104943 1.47 ENST00000532522.5
ENST00000527572.5
ENST00000527058.1
MAF1 homolog, negative regulator of RNA polymerase III
chr15_+_55408479 1.47 ENST00000569691.2
chromosome 15 open reading frame 65
chr5_-_178730651 1.47 ENST00000335815.7
zinc finger protein 354A
chr20_+_20052506 1.45 ENST00000340348.10
ENST00000245957.10
ENST00000674269.1
ENST00000377306.5
ENST00000377303.6
ENST00000475466.5
cilia and flagella associated protein 61
chr8_+_74350394 1.45 ENST00000675928.1
ENST00000676443.1
ENST00000676112.1
ENST00000674710.1
ENST00000434412.3
ENST00000675165.1
ENST00000674973.1
ENST00000220822.12
ENST00000675999.1
ENST00000523640.2
ENST00000524195.2
ENST00000675463.1
ENST00000676207.1
ENST00000674865.1
ENST00000676415.1
ganglioside induced differentiation associated protein 1
chr2_+_231781669 1.45 ENST00000410024.5
ENST00000611614.4
ENST00000409295.5
ENST00000409091.5
COP9 signalosome subunit 7B
chr19_-_5680488 1.45 ENST00000587589.1
ENST00000309324.9
mitochondrial contact site and cristae organizing system subunit 13
chr2_+_63588953 1.44 ENST00000409908.5
ENST00000442225.5
ENST00000233114.13
ENST00000539945.7
ENST00000409476.5
ENST00000436321.5
malate dehydrogenase 1
chr8_+_66667572 1.44 ENST00000520044.5
ENST00000519289.1
ENST00000521113.1
ENST00000661636.1
ENST00000521889.5
C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr3_+_4493471 1.43 ENST00000544951.6
ENST00000650294.1
inositol 1,4,5-trisphosphate receptor type 1
chr2_-_202911621 1.43 ENST00000261015.5
WD repeat domain 12
chr1_-_114757971 1.43 ENST00000261443.9
ENST00000534699.5
ENST00000339438.10
ENST00000358528.9
ENST00000529046.5
ENST00000525970.5
ENST00000369530.5
ENST00000530886.5
ENST00000610726.4
cold shock domain containing E1
chr1_-_113812448 1.43 ENST00000612242.4
ENST00000261441.9
round spermatid basic protein 1
chr15_-_74461102 1.42 ENST00000567435.5
ENST00000564488.5
ENST00000565130.5
ENST00000563081.1
ENST00000565335.5
ENST00000395081.7
ENST00000361351.8
ubiquitin like 7
chr3_+_101724633 1.42 ENST00000494050.5
centrosomal protein 97
chr19_+_5681000 1.41 ENST00000581893.5
ENST00000411793.6
ENST00000301382.8
ENST00000581773.5
ENST00000339423.7
ENST00000423665.6
ENST00000583928.5
ENST00000342970.6
ENST00000422535.6
ENST00000581521.5
hydroxysteroid 11-beta dehydrogenase 1 like
chr7_+_102748972 1.41 ENST00000413034.3
ENST00000409231.7
ENST00000418198.5
family with sequence similarity 185 member A
chr11_+_73647645 1.41 ENST00000545798.5
ENST00000539157.5
ENST00000546251.5
ENST00000535582.5
ENST00000538227.5
pleckstrin homology domain containing B1
chr2_-_69643703 1.40 ENST00000406297.7
ENST00000409085.9
AP2 associated kinase 1
chr12_+_56267249 1.40 ENST00000433805.6
coenzyme Q10A
chr16_+_28553908 1.39 ENST00000317058.8
SAGA complex associated factor 29
chr17_-_48101379 1.39 ENST00000581003.5
ENST00000225603.9
chromobox 1
chr16_+_53703963 1.39 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO alpha-ketoglutarate dependent dioxygenase
chr12_+_133080875 1.38 ENST00000412146.6
ENST00000544426.5
ENST00000355557.7
ENST00000319849.7
ENST00000440550.6
zinc finger protein 140
chr11_-_66371728 1.38 ENST00000357440.7
ENST00000619145.4
solute carrier family 29 member 2
chr7_-_135510074 1.38 ENST00000428680.6
ENST00000423368.6
ENST00000451834.5
ENST00000361528.8
ENST00000541284.5
ENST00000315544.6
CCR4-NOT transcription complex subunit 4
chr22_+_29767351 1.37 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr16_+_19523811 1.37 ENST00000396212.6
ENST00000381396.9
centriolar coiled-coil protein 110
chr12_+_56266934 1.37 ENST00000308197.10
coenzyme Q10A
chr8_-_28890164 1.37 ENST00000416984.6
integrator complex subunit 9
chr1_+_243256034 1.37 ENST00000366541.8
SHH signaling and ciliogenesis regulator SDCCAG8
chr19_+_48170654 1.36 ENST00000614654.2
ENST00000328759.11
zinc finger SWIM-type containing 9
chr7_+_107744134 1.36 ENST00000222597.6
ENST00000440859.8
ENST00000415884.6
Cbl proto-oncogene like 1
chr11_-_3057386 1.36 ENST00000529772.5
ENST00000278224.13
ENST00000380525.9
cysteinyl-tRNA synthetase 1
chr2_+_216412743 1.35 ENST00000358207.9
ENST00000434435.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1
chr19_-_44401575 1.35 ENST00000591679.5
ENST00000544719.6
ENST00000614994.5
ENST00000585868.1
ENST00000588212.1
zinc finger protein 285
novel protein
chr12_+_752551 1.35 ENST00000315939.11
ENST00000340908.9
ENST00000535572.5
WNK lysine deficient protein kinase 1
chr17_+_18225672 1.34 ENST00000621229.1
LLGL scribble cell polarity complex component 1
chr1_+_151166001 1.34 ENST00000368902.1
ENST00000368905.9
sodium channel modifier 1
chr2_+_63588992 1.34 ENST00000454035.5
malate dehydrogenase 1
chr1_+_1615839 1.33 ENST00000378712.5
MIB E3 ubiquitin protein ligase 2
chr5_-_173616588 1.33 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
biorientation of chromosomes in cell division 1
chr12_-_48852133 1.33 ENST00000552512.5
ENST00000551468.1
DEAD-box helicase 23
chr17_-_48101087 1.31 ENST00000393408.7
chromobox 1
chr20_-_20052389 1.31 ENST00000536226.2
crooked neck pre-mRNA splicing factor 1
chr16_+_25111823 1.31 ENST00000570981.1
leucine carboxyl methyltransferase 1
chr19_-_37467380 1.31 ENST00000316950.11
ENST00000591710.5
zinc finger protein 569
chr11_-_107565717 1.31 ENST00000428149.7
ENST00000429370.5
ENST00000417449.6
alkB homolog 8, tRNA methyltransferase
chr1_-_151008365 1.31 ENST00000361936.9
ENST00000361738.11
MINDY lysine 48 deubiquitinase 1
chr5_-_82278341 1.31 ENST00000510210.5
ENST00000512493.5
ENST00000296674.13
ENST00000507980.1
ENST00000511844.1
ENST00000651545.1
ribosomal protein S23
chr11_+_74171266 1.30 ENST00000328257.13
ENST00000398427.6
protein phosphatase methylesterase 1
chr4_-_2963327 1.30 ENST00000398071.4
ENST00000502735.5
ENST00000314262.10
ENST00000416614.7
NOP14 nucleolar protein
chr1_+_36224410 1.30 ENST00000469141.6
ENST00000648638.1
ENST00000354618.10
thyroid hormone receptor associated protein 3
chr14_+_77457861 1.30 ENST00000555133.5
activator of HSP90 ATPase activity 1
chr2_+_112542413 1.30 ENST00000417433.6
ENST00000263331.10
RNA polymerase I subunit B
chr15_+_74890005 1.29 ENST00000569931.5
ENST00000566377.5
ENST00000569233.5
ENST00000567132.5
ENST00000564633.5
ENST00000568907.5
ENST00000563422.5
ENST00000564003.5
ENST00000562800.5
ENST00000563786.5
ENST00000535694.5
ENST00000323744.10
ENST00000352410.9
ENST00000568828.5
ENST00000562606.5
ENST00000565576.5
ENST00000567570.5
mannose phosphate isomerase
chr19_+_7535697 1.29 ENST00000600737.6
patatin like phospholipase domain containing 6
chr5_-_36151853 1.29 ENST00000296603.5
LMBR1 domain containing 2
chr1_+_156767526 1.29 ENST00000271526.9
proline rich mitotic checkpoint control factor
chr4_-_47914569 1.28 ENST00000507489.2
nuclear transcription factor, X-box binding like 1
chr15_-_52569126 1.28 ENST00000569723.5
ENST00000567669.5
ENST00000569281.6
ENST00000563566.5
ENST00000567830.1
cAMP regulated phosphoprotein 19
chr20_-_37095985 1.28 ENST00000344359.7
ENST00000373664.8
RB transcriptional corepressor like 1
chr8_-_66667138 1.27 ENST00000310421.5
valosin containing protein interacting protein 1
chr12_+_56152579 1.27 ENST00000551834.5
ENST00000552568.5
myosin light chain 6B
chr19_-_19320488 1.27 ENST00000247001.10
ENST00000590439.2
SURP and G-patch domain containing 1
chr5_-_65624288 1.27 ENST00000381018.7
ENST00000274327.11
ENST00000231524.14
tripartite motif containing 23
chr17_-_48101287 1.27 ENST00000495350.5
ENST00000402583.5
chromobox 1
chr17_+_18225582 1.26 ENST00000316843.9
LLGL scribble cell polarity complex component 1
chr16_-_69385968 1.26 ENST00000567296.6
ENST00000254942.8
telomeric repeat binding factor 2
chr2_-_55232158 1.26 ENST00000407122.5
ENST00000401408.6
clathrin heavy chain linker domain containing 1
chr19_-_42242526 1.25 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr2_-_69643615 1.25 ENST00000409068.5
AP2 associated kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
2.0 5.9 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
1.0 11.0 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.0 2.9 GO:0006481 C-terminal protein methylation(GO:0006481)
0.9 6.3 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.9 4.4 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.8 0.8 GO:0036090 cleavage furrow ingression(GO:0036090)
0.8 3.2 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.7 2.7 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.7 6.5 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.6 1.8 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.6 3.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.6 1.7 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.6 2.9 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.6 2.3 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.5 8.2 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.5 2.1 GO:0051228 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.5 0.5 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.5 3.0 GO:2001034 histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.5 1.5 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.5 2.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.5 1.4 GO:0042245 RNA repair(GO:0042245)
0.5 4.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.4 1.3 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.4 1.3 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.4 2.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 3.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.4 1.3 GO:0010905 regulation of UDP-glucose catabolic process(GO:0010904) negative regulation of UDP-glucose catabolic process(GO:0010905) regulation of glycogen synthase activity, transferring glucose-1-phosphate(GO:1904226) negative regulation of glycogen synthase activity, transferring glucose-1-phosphate(GO:1904227)
0.4 1.6 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.4 1.2 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.4 1.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.4 1.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.4 3.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 2.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.3 1.0 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.3 2.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 1.9 GO:0070142 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.3 0.9 GO:0006173 dADP biosynthetic process(GO:0006173)
0.3 4.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 0.9 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.3 2.7 GO:0035494 SNARE complex disassembly(GO:0035494)
0.3 0.9 GO:0031445 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 4.3 GO:0006108 malate metabolic process(GO:0006108)
0.3 4.0 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 3.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 1.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.3 1.6 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.3 0.8 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.3 1.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 1.5 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.3 3.6 GO:0006449 regulation of translational termination(GO:0006449)
0.3 0.8 GO:1902774 vacuole fusion, non-autophagic(GO:0042144) late endosome to lysosome transport(GO:1902774)
0.2 3.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 0.7 GO:0032053 ciliary basal body organization(GO:0032053)
0.2 1.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 4.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.2 1.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 2.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.2 1.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.7 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 1.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.2 0.6 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.2 2.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 1.5 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.2 1.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 0.8 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.2 1.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 1.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 1.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 1.5 GO:0044211 CTP salvage(GO:0044211)
0.2 1.1 GO:0006574 valine catabolic process(GO:0006574)
0.2 0.4 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.2 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 1.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.2 2.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 6.9 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 3.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2 5.1 GO:0016180 snRNA processing(GO:0016180)
0.2 7.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 0.5 GO:2001311 lysobisphosphatidic acid metabolic process(GO:2001311)
0.2 1.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 2.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.2 1.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.2 2.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.3 GO:0007000 nucleolus organization(GO:0007000)
0.2 0.8 GO:0048254 snoRNA localization(GO:0048254)
0.2 1.1 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
0.2 1.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 3.0 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.2 2.6 GO:0042407 cristae formation(GO:0042407)
0.2 1.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1 1.0 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 4.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 3.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 2.9 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 1.0 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.6 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 2.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.4 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.5 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 5.8 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 1.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.6 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.5 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.4 GO:1902416 regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416) regulation of RNA binding(GO:1905214) positive regulation of RNA binding(GO:1905216)
0.1 1.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
0.1 1.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444) enucleate erythrocyte differentiation(GO:0043353)
0.1 3.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.3 GO:0051805 evasion or tolerance of host immune response(GO:0020012) evasion or tolerance of host defense response(GO:0030682) evasion or tolerance by virus of host immune response(GO:0030683) evasion or tolerance of immune response of other organism involved in symbiotic interaction(GO:0051805) evasion or tolerance of defense response of other organism involved in symbiotic interaction(GO:0051807)
0.1 1.0 GO:0030242 pexophagy(GO:0030242)
0.1 1.2 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 0.2 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.1 2.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 1.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 0.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.9 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 0.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 1.6 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.1 0.4 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.7 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.5 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.4 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.3 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1 4.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 1.7 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.1 0.5 GO:0035624 receptor transactivation(GO:0035624)
0.1 2.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 2.5 GO:0030488 tRNA methylation(GO:0030488)
0.1 2.5 GO:0018126 protein hydroxylation(GO:0018126)
0.1 1.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.4 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.4 GO:0061511 centriole elongation(GO:0061511)
0.1 4.1 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 1.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 4.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.2 GO:0001188 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 1.5 GO:0045116 protein neddylation(GO:0045116)
0.1 0.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 0.4 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.1 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.1 1.4 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.1 0.2 GO:0001555 oocyte growth(GO:0001555)
0.1 0.9 GO:1904851 positive regulation of establishment of protein localization to telomere(GO:1904851)
0.1 1.0 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.5 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.8 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 0.3 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 6.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.2 GO:0014028 notochord formation(GO:0014028)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 5.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.5 GO:0000012 single strand break repair(GO:0000012)
0.0 1.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.6 GO:0015705 iodide transport(GO:0015705)
0.0 0.5 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 1.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.6 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 1.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 1.5 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 1.5 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 3.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 3.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 2.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 2.6 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 7.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 2.4 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.4 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 1.5 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.5 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 4.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 1.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.7 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) proton-transporting two-sector ATPase complex assembly(GO:0070071) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.4 GO:0030638 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 2.0 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 1.6 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.9 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.6 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 1.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 1.8 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 1.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 2.5 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 1.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.6 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.3 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 2.1 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 1.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 1.3 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 2.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.7 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.7 GO:0048820 hair follicle maturation(GO:0048820)
0.0 1.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 3.1 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 5.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 1.7 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 1.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.8 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 1.4 GO:0003341 cilium movement(GO:0003341)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 2.5 GO:0045333 cellular respiration(GO:0045333)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 2.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 1.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 79.8 GO:0006351 transcription, DNA-templated(GO:0006351)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0043297 apical junction assembly(GO:0043297)
0.0 0.1 GO:0070266 necroptotic process(GO:0070266)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.6 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 2.9 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.6 GO:0072687 meiotic spindle(GO:0072687)
0.8 4.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.7 3.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.7 3.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.7 2.7 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.7 6.5 GO:0055028 cortical microtubule(GO:0055028)
0.6 1.9 GO:0070939 Dsl1p complex(GO:0070939)
0.6 2.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.5 1.5 GO:0030689 Noc complex(GO:0030689)
0.5 4.1 GO:1990745 EARP complex(GO:1990745)
0.5 1.5 GO:0001534 radial spoke(GO:0001534)
0.4 1.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.4 2.9 GO:0061617 MICOS complex(GO:0061617)
0.4 13.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 3.2 GO:0002177 manchette(GO:0002177)
0.4 2.4 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.4 1.1 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.4 1.1 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.4 1.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.4 1.1 GO:0034515 proteasome storage granule(GO:0034515)
0.3 4.0 GO:0001940 male pronucleus(GO:0001940)
0.3 5.7 GO:0032039 integrator complex(GO:0032039)
0.3 1.6 GO:0035363 histone locus body(GO:0035363)
0.3 0.9 GO:0055087 Ski complex(GO:0055087)
0.3 4.5 GO:0031209 SCAR complex(GO:0031209)
0.3 0.8 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.3 1.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 3.1 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.9 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 1.4 GO:0070545 PeBoW complex(GO:0070545)
0.2 2.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.2 3.2 GO:0030897 HOPS complex(GO:0030897)
0.2 0.7 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.2 0.5 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.2 1.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 2.4 GO:0070187 telosome(GO:0070187)
0.2 1.0 GO:0036449 microtubule minus-end(GO:0036449)
0.2 4.6 GO:0000242 pericentriolar material(GO:0000242)
0.2 1.3 GO:0097165 nuclear stress granule(GO:0097165)
0.2 0.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.6 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 0.5 GO:0032116 SMC loading complex(GO:0032116)
0.1 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 3.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.6 GO:0071817 MMXD complex(GO:0071817)
0.1 3.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 3.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 3.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 4.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 2.2 GO:0071203 WASH complex(GO:0071203)
0.1 3.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 2.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 4.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.6 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 2.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 1.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.2 GO:0042382 paraspeckles(GO:0042382)
0.1 0.8 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.1 3.0 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 1.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 1.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0035859 Seh1-associated complex(GO:0035859) Iml1 complex(GO:1990130)
0.1 0.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 2.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 4.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.4 GO:0000801 central element(GO:0000801)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 0.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 1.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 6.7 GO:0031672 A band(GO:0031672)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 2.4 GO:0030057 desmosome(GO:0030057)
0.1 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.0 GO:0032040 small-subunit processome(GO:0032040)
0.0 2.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 3.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 2.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 2.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0098798 mitochondrial protein complex(GO:0098798)
0.0 1.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.8 GO:0070938 contractile ring(GO:0070938)
0.0 1.6 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 4.1 GO:0043195 terminal bouton(GO:0043195)
0.0 1.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)
0.0 1.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 4.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 1.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 6.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 7.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 1.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.6 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 4.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.2 GO:0001650 fibrillar center(GO:0001650)
0.0 4.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
2.5 7.6 GO:0031862 prostanoid receptor binding(GO:0031862)
1.5 4.4 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
1.4 4.3 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
1.4 4.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
1.4 4.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.0 2.9 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
1.0 2.9 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.9 6.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.8 3.2 GO:0047708 biotinidase activity(GO:0047708)
0.7 11.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.7 2.7 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.7 2.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.6 2.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.6 1.7 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.4 2.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.4 2.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4 7.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 2.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 3.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 1.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.4 4.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 1.4 GO:0035514 DNA demethylase activity(GO:0035514)
0.3 8.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 2.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 2.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.3 1.7 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.3 2.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 3.9 GO:0036310 annealing helicase activity(GO:0036310)
0.3 1.4 GO:0003896 DNA primase activity(GO:0003896)
0.3 1.6 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.3 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3 0.8 GO:0071209 U7 snRNA binding(GO:0071209)
0.3 2.8 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 2.1 GO:0070728 leucine binding(GO:0070728)
0.2 1.1 GO:1903135 cupric ion binding(GO:1903135)
0.2 0.8 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 6.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 2.6 GO:0034618 arginine binding(GO:0034618)
0.2 3.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 1.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 1.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.5 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.2 2.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.8 GO:0030622 U4atac snRNA binding(GO:0030622)
0.2 0.6 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 1.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 4.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.9 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 3.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.9 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.7 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 4.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 2.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.6 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 7.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.4 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 2.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.4 GO:0000182 rDNA binding(GO:0000182)
0.1 0.5 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.9 GO:0051373 FATZ binding(GO:0051373)
0.1 1.7 GO:0051400 BH domain binding(GO:0051400)
0.1 1.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 3.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.8 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 5.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 3.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0015182 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.1 0.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 4.9 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 1.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 1.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.4 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 4.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.7 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.6 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.6 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 3.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 5.0 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 2.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.0 1.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.1 GO:0005522 profilin binding(GO:0005522)
0.0 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 1.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 3.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 1.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 1.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 5.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 1.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 1.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 4.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 1.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 1.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 1.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 2.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 2.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 60.8 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 3.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.1 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0032451 demethylase activity(GO:0032451)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 25.7 GO:0003677 DNA binding(GO:0003677)
0.0 4.6 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 3.1 GO:0000149 SNARE binding(GO:0000149)
0.0 3.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)
0.0 1.1 GO:0015631 tubulin binding(GO:0015631)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 5.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 6.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 5.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.1 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 3.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 2.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 4.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 26.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 6.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 2.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 5.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 4.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 4.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 1.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 3.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 64.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 2.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 4.2 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 4.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 2.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 1.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 3.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 2.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling