Illumina Body Map 2 (GSE30611)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
SMAD1 | hg38_v1_chr4_+_145481691_145481712 | -0.42 | 1.8e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 145.6 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
1.6 | 140.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
1.1 | 129.3 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.4 | 74.0 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.5 | 46.5 | GO:0006968 | cellular defense response(GO:0006968) |
0.3 | 39.0 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
0.4 | 22.9 | GO:0006953 | acute-phase response(GO:0006953) |
0.9 | 21.5 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
0.1 | 20.3 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 18.4 | GO:0006955 | immune response(GO:0006955) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 142.6 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.2 | 72.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 66.5 | GO:0005615 | extracellular space(GO:0005615) |
0.5 | 63.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
0.3 | 49.2 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.2 | 40.2 | GO:0072562 | blood microparticle(GO:0072562) |
1.2 | 38.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.5 | 35.0 | GO:0001772 | immunological synapse(GO:0001772) |
2.6 | 26.1 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
0.1 | 24.9 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 262.5 | GO:0003823 | antigen binding(GO:0003823) |
2.0 | 141.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
2.6 | 28.2 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
0.3 | 27.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.2 | 27.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.5 | 26.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
1.4 | 25.3 | GO:0019864 | IgG binding(GO:0019864) |
0.0 | 24.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.2 | 22.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.2 | 20.7 | GO:0004896 | cytokine receptor activity(GO:0004896) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 75.8 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
1.0 | 66.5 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.4 | 41.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.4 | 25.7 | PID BCR 5PATHWAY | BCR signaling pathway |
0.4 | 23.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
0.5 | 23.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.2 | 20.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.5 | 20.5 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
0.3 | 16.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.2 | 12.8 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 83.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.4 | 42.8 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
1.6 | 35.0 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.4 | 31.9 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
0.4 | 30.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.1 | 22.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
1.7 | 17.3 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
0.4 | 17.0 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.1 | 15.5 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
1.4 | 14.9 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |