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Illumina Body Map 2 (GSE30611)

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Results for SMAD2

Z-value: 1.57

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Transcription factors associated with SMAD2

Gene Symbol Gene ID Gene Info
SMAD2
ENSG00000175387.16 SMAD family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD2hg38_v1_chr18_-_47930630_479306810.522.3e-03Click!

Activity profile of SMAD2 motif

Sorted Z-values of SMAD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_735026 8.32 ENST00000592155.5
ENST00000590161.2
PALM
paralemmin
chr8_+_105319541 5.05 ENST00000520492.5
ZFPM2
zinc finger protein, FOG family member 2
chr17_-_15262537 5.05 ENST00000395936.7
ENST00000675819.1
ENST00000674707.1
ENST00000675854.1
ENST00000426385.4
ENST00000395938.7
ENST00000612492.5
ENST00000675808.1
PMP22
peripheral myelin protein 22
chr19_+_7515292 4.81 ENST00000596712.1
ZNF358
zinc finger protein 358
chr1_+_160115715 4.58 ENST00000361216.8
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr17_-_10114546 4.06 ENST00000323816.8
GAS7
growth arrest specific 7
chr1_+_160115777 3.88 ENST00000392233.7
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr1_+_159171607 3.63 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr12_+_53050179 3.50 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
TNS2
tensin 2
chr1_+_160127672 3.47 ENST00000447527.1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr1_-_201946469 3.33 ENST00000367288.5
LMOD1
leiomodin 1
chr1_-_44017296 3.29 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
SLC6A9
solute carrier family 6 member 9
chrX_+_38561530 3.24 ENST00000378482.7
ENST00000286824.6
TSPAN7
tetraspanin 7
chr17_+_7407838 3.23 ENST00000302926.7
NLGN2
neuroligin 2
chr1_+_99646025 3.17 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr20_+_44715360 3.04 ENST00000190983.5
CCN5
cellular communication network factor 5
chr11_-_107858777 3.04 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr11_-_107719657 3.03 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr1_-_201946571 3.01 ENST00000616739.1
LMOD1
leiomodin 1
chr11_-_126062782 2.97 ENST00000531738.6
CDON
cell adhesion associated, oncogene regulated
chr16_+_28878480 2.94 ENST00000395503.9
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr7_-_102616692 2.83 ENST00000521076.5
ENST00000462172.5
ENST00000522801.5
ENST00000262940.12
ENST00000449970.6
RASA4
RAS p21 protein activator 4
chr22_+_22357739 2.76 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr20_+_44714853 2.57 ENST00000372865.4
CCN5
cellular communication network factor 5
chr16_+_28878382 2.52 ENST00000357084.7
ATP2A1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr7_-_102517755 2.52 ENST00000306682.6
ENST00000465829.6
ENST00000541662.5
RASA4B
RAS p21 protein activator 4B
chr16_+_55479188 2.47 ENST00000219070.9
MMP2
matrix metallopeptidase 2
chr12_-_55712402 2.43 ENST00000452168.6
ITGA7
integrin subunit alpha 7
chrX_+_102651366 2.42 ENST00000415986.5
ENST00000444152.5
ENST00000361600.9
GPRASP1
G protein-coupled receptor associated sorting protein 1
chr11_-_66317037 2.40 ENST00000311330.4
CD248
CD248 molecule
chr11_-_107858561 2.33 ENST00000375682.8
SLC35F2
solute carrier family 35 member F2
chr17_+_7888783 2.32 ENST00000330494.12
ENST00000358181.8
CHD3
chromodomain helicase DNA binding protein 3
chr7_-_100895878 2.18 ENST00000419336.6
ENST00000241069.11
ENST00000411582.4
ENST00000302913.8
ACHE
acetylcholinesterase (Cartwright blood group)
chr14_-_104978360 2.12 ENST00000333244.6
AHNAK2
AHNAK nucleoprotein 2
chr6_+_32164586 2.00 ENST00000333845.11
ENST00000395512.5
ENST00000432129.1
EGFL8
EGF like domain multiple 8
chr12_+_6927946 1.97 ENST00000396684.3
ATN1
atrophin 1
chr9_-_133131109 1.96 ENST00000372062.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr19_-_35135011 1.95 ENST00000310123.8
LGI4
leucine rich repeat LGI family member 4
chr22_-_24245059 1.94 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
GGT5
gamma-glutamyltransferase 5
chr14_-_106038355 1.87 ENST00000390597.3
IGHV2-5
immunoglobulin heavy variable 2-5
chr16_+_55478830 1.77 ENST00000568715.5
MMP2
matrix metallopeptidase 2
chrX_-_48470243 1.67 ENST00000429543.2
ENST00000620913.5
SLC38A5
solute carrier family 38 member 5
chr2_-_219309484 1.67 ENST00000409251.7
ENST00000451506.5
ENST00000446182.5
PTPRN
protein tyrosine phosphatase receptor type N
chr3_-_195876635 1.65 ENST00000672669.1
ENST00000672886.1
ENST00000672098.1
ENST00000671767.1
ENST00000672548.1
TNK2
tyrosine kinase non receptor 2
chr22_+_19718390 1.63 ENST00000383045.7
ENST00000438754.6
SEPTIN5
septin 5
chr12_+_53050014 1.48 ENST00000314250.11
TNS2
tensin 2
chr22_-_36028773 1.44 ENST00000438146.7
RBFOX2
RNA binding fox-1 homolog 2
chrX_-_48470163 1.42 ENST00000595796.5
SLC38A5
solute carrier family 38 member 5
chrX_+_101488044 1.40 ENST00000423738.4
ARMCX4
armadillo repeat containing X-linked 4
chr10_+_71212524 1.37 ENST00000335350.10
UNC5B
unc-5 netrin receptor B
chr14_+_30874541 1.37 ENST00000396618.9
ENST00000644874.2
ENST00000555117.2
ENST00000475087.5
COCH
cochlin
chr1_-_58784035 1.37 ENST00000371222.4
JUN
Jun proto-oncogene, AP-1 transcription factor subunit
chr19_+_16888991 1.35 ENST00000248076.4
F2RL3
F2R like thrombin or trypsin receptor 3
chr20_+_32010429 1.34 ENST00000452892.3
ENST00000262659.12
CCM2L
CCM2 like scaffold protein
chr1_-_206003385 1.33 ENST00000617070.5
RAB7B
RAB7B, member RAS oncogene family
chr13_-_26760741 1.32 ENST00000405846.5
GPR12
G protein-coupled receptor 12
chr1_-_41242106 1.32 ENST00000337495.9
ENST00000372597.5
ENST00000372596.5
SCMH1
Scm polycomb group protein homolog 1
chr2_+_167868948 1.32 ENST00000392690.3
B3GALT1
beta-1,3-galactosyltransferase 1
chr2_+_27014746 1.28 ENST00000648289.1
ENST00000458529.5
ENST00000402218.1
MAPRE3
microtubule associated protein RP/EB family member 3
chr10_-_73433550 1.27 ENST00000299432.7
MSS51
MSS51 mitochondrial translational activator
chr2_-_219309350 1.26 ENST00000295718.7
PTPRN
protein tyrosine phosphatase receptor type N
chr1_-_44031352 1.26 ENST00000372306.7
ENST00000475075.6
SLC6A9
solute carrier family 6 member 9
chr19_+_49644830 1.25 ENST00000601038.5
ENST00000595242.3
SCAF1
SR-related CTD associated factor 1
chr19_-_45785659 1.23 ENST00000537879.1
ENST00000596586.5
ENST00000595946.1
DMWD
ENSG00000268434.5
DM1 locus, WD repeat containing
novel protein
chr14_+_101964561 1.21 ENST00000643508.2
ENST00000680137.1
ENST00000644881.2
ENST00000645149.2
ENST00000681574.1
ENST00000360184.10
ENST00000679720.1
ENST00000645114.2
DYNC1H1
dynein cytoplasmic 1 heavy chain 1
chr11_-_75668566 1.21 ENST00000526740.3
MAP6
microtubule associated protein 6
chr7_-_14841267 1.19 ENST00000406247.7
ENST00000399322.7
DGKB
diacylglycerol kinase beta
chr3_+_124094663 1.18 ENST00000460856.5
ENST00000240874.7
KALRN
kalirin RhoGEF kinase
chr6_+_56955097 1.15 ENST00000370746.8
ENST00000370748.7
BEND6
BEN domain containing 6
chr12_-_10098977 1.14 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr16_-_4937064 1.13 ENST00000590782.6
ENST00000345988.7
PPL
periplakin
chr9_+_34990250 1.12 ENST00000454002.6
ENST00000545841.5
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5
chr15_+_96332432 1.12 ENST00000559679.1
ENST00000394171.6
NR2F2
nuclear receptor subfamily 2 group F member 2
chr9_-_98708856 1.12 ENST00000259455.4
GABBR2
gamma-aminobutyric acid type B receptor subunit 2
chr8_-_20303955 1.10 ENST00000381569.5
LZTS1
leucine zipper tumor suppressor 1
chr11_-_117295485 1.09 ENST00000680971.1
BACE1
beta-secretase 1
chr6_+_39792298 1.07 ENST00000633794.1
ENST00000274867.9
DAAM2
dishevelled associated activator of morphogenesis 2
chr5_+_141382702 1.07 ENST00000617050.1
ENST00000518325.2
PCDHGA7
protocadherin gamma subfamily A, 7
chr5_-_151686953 1.06 ENST00000538026.5
ENST00000522348.1
ENST00000521569.1
SPARC
secreted protein acidic and cysteine rich
chr4_-_41214602 1.06 ENST00000508676.5
ENST00000506352.5
ENST00000295974.12
APBB2
amyloid beta precursor protein binding family B member 2
chr1_-_151146611 1.04 ENST00000341697.7
ENST00000368914.8
SEMA6C
semaphorin 6C
chr1_-_149812359 1.03 ENST00000369167.2
ENST00000545683.1
H2BC18
H2B clustered histone 18
chr4_-_5888400 1.03 ENST00000397890.6
CRMP1
collapsin response mediator protein 1
chr19_+_35775530 1.02 ENST00000314737.9
ENST00000007510.8
ARHGAP33
Rho GTPase activating protein 33
chr11_-_75669028 1.02 ENST00000304771.8
MAP6
microtubule associated protein 6
chr7_-_100896123 1.00 ENST00000428317.7
ACHE
acetylcholinesterase (Cartwright blood group)
chr19_-_45602153 1.00 ENST00000544371.1
ENST00000323040.5
OPA3
GPR4
outer mitochondrial membrane lipid metabolism regulator OPA3
G protein-coupled receptor 4
chr3_+_124094696 0.99 ENST00000360013.7
ENST00000684186.1
ENST00000684276.1
KALRN
kalirin RhoGEF kinase
chr11_+_75562056 0.99 ENST00000533603.5
SERPINH1
serpin family H member 1
chr4_-_41214535 0.97 ENST00000508593.6
APBB2
amyloid beta precursor protein binding family B member 2
chr17_+_42288429 0.97 ENST00000676631.1
ENST00000677893.1
STAT5A
signal transducer and activator of transcription 5A
chr17_-_7207245 0.97 ENST00000649971.1
DLG4
discs large MAGUK scaffold protein 4
chr4_-_113761563 0.96 ENST00000394522.7
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr22_+_22822658 0.96 ENST00000620395.2
IGLV2-8
immunoglobulin lambda variable 2-8
chrX_+_153764233 0.96 ENST00000361971.10
PLXNB3
plexin B3
chr7_+_66629023 0.96 ENST00000639879.1
ENST00000640851.1
KCTD7
potassium channel tetramerization domain containing 7
chr19_+_16889154 0.95 ENST00000599210.1
F2RL3
F2R like thrombin or trypsin receptor 3
chr5_+_74767234 0.93 ENST00000610426.5
NSA2
NSA2 ribosome biogenesis factor
chr6_+_39793008 0.92 ENST00000398904.6
DAAM2
dishevelled associated activator of morphogenesis 2
chr19_+_47130782 0.92 ENST00000597808.5
ENST00000413379.7
ENST00000600706.5
ENST00000270225.12
ENST00000598840.5
ENST00000600753.1
ENST00000392776.3
SAE1
SUMO1 activating enzyme subunit 1
chr3_+_40505992 0.91 ENST00000420891.5
ENST00000314529.10
ENST00000418905.1
ZNF620
zinc finger protein 620
chr4_-_41214474 0.91 ENST00000503503.5
ENST00000509446.5
ENST00000503264.5
ENST00000508707.5
APBB2
amyloid beta precursor protein binding family B member 2
chr12_+_3491189 0.91 ENST00000382622.4
PRMT8
protein arginine methyltransferase 8
chr6_+_30884960 0.90 ENST00000508312.5
ENST00000512336.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_-_219308963 0.90 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
PTPRN
protein tyrosine phosphatase receptor type N
chr4_-_184217854 0.89 ENST00000296741.7
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr12_+_100794769 0.89 ENST00000392977.8
ENST00000546991.1
ENST00000392979.7
ANO4
anoctamin 4
chr22_+_22327298 0.89 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chrX_+_153764178 0.88 ENST00000538966.5
PLXNB3
plexin B3
chr17_-_78925376 0.87 ENST00000262768.11
TIMP2
TIMP metallopeptidase inhibitor 2
chr1_-_206003442 0.87 ENST00000623893.1
RAB7B
RAB7B, member RAS oncogene family
chr10_-_14330879 0.87 ENST00000357447.7
FRMD4A
FERM domain containing 4A
chr9_+_130693756 0.87 ENST00000546165.5
ENST00000372352.7
ENST00000372358.10
ENST00000372351.7
ENST00000372350.7
ENST00000495699.2
EXOSC2
exosome component 2
chr6_+_39792993 0.86 ENST00000538976.5
DAAM2
dishevelled associated activator of morphogenesis 2
chrX_-_135098695 0.84 ENST00000433425.4
SMIM10L2B
small integral membrane protein 10 like 2B
chrX_+_153494970 0.83 ENST00000331595.9
ENST00000431891.1
BGN
biglycan
chr12_-_57016517 0.83 ENST00000441881.5
ENST00000458521.7
TAC3
tachykinin precursor 3
chr4_-_113761068 0.83 ENST00000342666.9
ENST00000514328.5
ENST00000515496.5
ENST00000508738.5
ENST00000379773.6
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr12_-_10098940 0.82 ENST00000420265.2
CLEC1A
C-type lectin domain family 1 member A
chr7_+_143382996 0.81 ENST00000446634.1
ZYX
zyxin
chr9_+_130835246 0.80 ENST00000318560.6
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
chr14_+_80955577 0.80 ENST00000642209.1
ENST00000298171.7
TSHR
thyroid stimulating hormone receptor
chr5_-_88731827 0.80 ENST00000627170.2
MEF2C
myocyte enhancer factor 2C
chrX_-_107775740 0.80 ENST00000372383.9
TSC22D3
TSC22 domain family member 3
chr10_+_18261080 0.80 ENST00000377319.8
ENST00000377331.8
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr19_+_35775515 0.80 ENST00000378944.9
ARHGAP33
Rho GTPase activating protein 33
chr19_-_43781249 0.79 ENST00000615047.4
KCNN4
potassium calcium-activated channel subfamily N member 4
chr4_-_113761170 0.79 ENST00000505990.5
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr6_+_43132472 0.78 ENST00000489707.5
PTK7
protein tyrosine kinase 7 (inactive)
chr17_+_7705193 0.78 ENST00000226091.3
EFNB3
ephrin B3
chr17_+_42288076 0.78 ENST00000546010.6
STAT5A
signal transducer and activator of transcription 5A
chr4_-_41214450 0.77 ENST00000513140.5
APBB2
amyloid beta precursor protein binding family B member 2
chr11_+_66857056 0.77 ENST00000309602.5
ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr7_+_149719345 0.76 ENST00000497895.5
KRBA1
KRAB-A domain containing 1
chr16_-_2009797 0.75 ENST00000563630.6
ENST00000562103.2
ZNF598
zinc finger protein 598, E3 ubiquitin ligase
chr6_+_30885225 0.73 ENST00000421124.6
ENST00000512725.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_-_60550900 0.73 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr22_+_37560472 0.72 ENST00000430687.1
ENST00000249014.5
CDC42EP1
CDC42 effector protein 1
chr5_+_14441043 0.72 ENST00000639876.2
TRIO
trio Rho guanine nucleotide exchange factor
chr7_+_66629078 0.71 ENST00000449064.6
ENST00000638540.1
ENST00000640234.1
KCTD7
potassium channel tetramerization domain containing 7
chr3_-_71130892 0.70 ENST00000491238.7
ENST00000674446.1
FOXP1
forkhead box P1
chr5_+_64768921 0.70 ENST00000381070.8
ENST00000508024.1
CWC27
CWC27 spliceosome associated cyclophilin
chr5_+_74766981 0.69 ENST00000296802.9
NSA2
NSA2 ribosome biogenesis factor
chr11_-_18791563 0.68 ENST00000396168.1
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr15_+_45587397 0.67 ENST00000565216.5
BLOC1S6
biogenesis of lysosomal organelles complex 1 subunit 6
chr15_+_45587766 0.65 ENST00000565409.5
ENST00000564765.1
BLOC1S6
biogenesis of lysosomal organelles complex 1 subunit 6
chr4_-_102828022 0.64 ENST00000502690.5
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr5_-_151686908 0.63 ENST00000231061.9
SPARC
secreted protein acidic and cysteine rich
chr4_+_37244735 0.63 ENST00000309447.6
NWD2
NACHT and WD repeat domain containing 2
chr1_+_26159071 0.63 ENST00000374268.5
FAM110D
family with sequence similarity 110 member D
chr15_+_45587230 0.63 ENST00000567461.5
BLOC1S6
biogenesis of lysosomal organelles complex 1 subunit 6
chr4_-_113761724 0.62 ENST00000511664.6
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr5_+_134526100 0.61 ENST00000395003.5
JADE2
jade family PHD finger 2
chr4_-_113761441 0.61 ENST00000394524.7
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chrX_-_63754664 0.60 ENST00000677315.1
ENST00000636392.1
ENST00000637040.1
ENST00000637178.1
ENST00000637557.1
ENST00000636048.1
ENST00000638021.1
ENST00000672513.1
ENSG00000288661.1
ARHGEF9
novel protein
Cdc42 guanine nucleotide exchange factor 9
chr19_-_14496088 0.60 ENST00000393033.9
ENST00000345425.6
ENST00000586027.5
ENST00000591349.5
ENST00000587210.1
GIPC1
GIPC PDZ domain containing family member 1
chr20_+_58651785 0.59 ENST00000358029.8
STX16
syntaxin 16
chr1_-_153985366 0.59 ENST00000614713.4
RAB13
RAB13, member RAS oncogene family
chr4_+_673518 0.58 ENST00000506838.5
MYL5
myosin light chain 5
chr5_-_159208066 0.57 ENST00000519865.5
ENST00000521606.6
RNF145
ring finger protein 145
chr16_+_3305472 0.56 ENST00000574298.6
ENST00000669516.2
ZNF75A
zinc finger protein 75a
chr19_-_14114156 0.55 ENST00000589994.6
PRKACA
protein kinase cAMP-activated catalytic subunit alpha
chr3_-_71130557 0.55 ENST00000497355.7
FOXP1
forkhead box P1
chr5_-_43412323 0.55 ENST00000361115.4
CCL28
C-C motif chemokine ligand 28
chr1_-_151146643 0.53 ENST00000613223.1
SEMA6C
semaphorin 6C
chr5_+_175871570 0.53 ENST00000512824.5
ENST00000393745.8
CPLX2
complexin 2
chr15_+_68277724 0.52 ENST00000306917.5
FEM1B
fem-1 homolog B
chr1_+_36307090 0.52 ENST00000505871.7
SH3D21
SH3 domain containing 21
chr3_-_71130963 0.50 ENST00000649695.2
FOXP1
forkhead box P1
chrX_-_20141810 0.50 ENST00000379593.1
ENST00000379607.10
EIF1AX
eukaryotic translation initiation factor 1A X-linked
chr22_+_22734577 0.50 ENST00000390310.3
IGLV2-18
immunoglobulin lambda variable 2-18
chrX_-_151974668 0.50 ENST00000370328.4
GABRE
gamma-aminobutyric acid type A receptor subunit epsilon
chr19_+_11355386 0.50 ENST00000251473.9
ENST00000591329.5
ENST00000586380.5
PLPPR2
phospholipid phosphatase related 2
chr7_-_97024821 0.50 ENST00000648378.1
ENST00000486603.2
DLX5
distal-less homeobox 5
chr16_+_32847692 0.50 ENST00000567458.2
IGHV2OR16-5
immunoglobulin heavy variable 2/OR16-5 (non-functional)
chr15_+_82262781 0.49 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000682753.1
ENST00000566861.5
ENST00000565432.1
SAXO2
stabilizer of axonemal microtubules 2
chr11_-_75668434 0.47 ENST00000434603.2
MAP6
microtubule associated protein 6
chr7_+_102363874 0.47 ENST00000496391.5
PRKRIP1
PRKR interacting protein 1
chr12_-_8612850 0.46 ENST00000229335.11
ENST00000537228.5
AICDA
activation induced cytidine deaminase
chr3_+_3799424 0.45 ENST00000319331.4
LRRN1
leucine rich repeat neuronal 1
chr5_+_134526176 0.44 ENST00000681820.1
ENST00000512386.6
ENST00000612830.2
JADE2
jade family PHD finger 2
chr15_+_45587580 0.44 ENST00000566801.5
ENST00000565323.6
ENST00000568816.5
BLOC1S6
biogenesis of lysosomal organelles complex 1 subunit 6
chr19_-_49362376 0.44 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEAD2
TEA domain transcription factor 2
chrX_-_153495476 0.43 ENST00000370210.3
HAUS7
HAUS augmin like complex subunit 7
chr8_-_95269190 0.43 ENST00000286688.6
C8orf37
chromosome 8 open reading frame 37
chr5_-_74640575 0.42 ENST00000651128.1
ENC1
ectodermal-neural cortex 1
chr7_+_130380339 0.41 ENST00000481342.5
ENST00000604896.5
ENST00000011292.8
CPA1
carboxypeptidase A1
chr6_-_56954747 0.41 ENST00000680361.1
DST
dystonin
chr22_+_22352911 0.40 ENST00000390293.1
IGLV5-48
immunoglobulin lambda variable 5-48 (non-functional)
chr10_-_124093582 0.39 ENST00000462406.1
ENST00000435907.6
CHST15
carbohydrate sulfotransferase 15
chr21_-_46285608 0.39 ENST00000291688.6
MCM3AP
minichromosome maintenance complex component 3 associated protein
chr1_-_1307861 0.38 ENST00000354700.10
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr11_-_33892010 0.37 ENST00000257818.3
LMO2
LIM domain only 2
chr9_-_28670285 0.36 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr11_-_3837858 0.36 ENST00000396979.1
RHOG
ras homolog family member G
chr14_+_80955366 0.36 ENST00000342443.10
TSHR
thyroid stimulating hormone receptor
chr6_-_152168349 0.36 ENST00000539504.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr11_-_18791768 0.36 ENST00000358540.7
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr6_-_152168291 0.35 ENST00000354674.5
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr1_-_2801717 0.35 ENST00000401095.8
TTC34
tetratricopeptide repeat domain 34

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 11.9 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
1.8 5.5 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
1.5 4.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.3 3.8 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
1.0 8.3 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
1.0 3.0 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.8 2.4 GO:1990172 G-protein coupled receptor catabolic process(GO:1990172)
0.8 3.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.7 5.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 6.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 3.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.5 1.8 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.4 1.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 1.3 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 4.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 2.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.3 1.4 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.3 1.2 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.3 1.1 GO:0009956 radial pattern formation(GO:0009956)
0.2 3.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 0.9 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.2 1.7 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.2 1.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 4.6 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 2.2 GO:0046959 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.2 0.9 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) CUT metabolic process(GO:0071043)
0.2 1.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.2 1.0 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.2 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 3.1 GO:0015816 glycine transport(GO:0015816)
0.2 5.1 GO:0032060 bleb assembly(GO:0032060)
0.2 0.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 1.8 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.2 1.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 1.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 2.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 5.0 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.7 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 2.6 GO:0060033 anatomical structure regression(GO:0060033)
0.1 2.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 2.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.9 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1 1.0 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.4 GO:0003143 embryonic heart tube morphogenesis(GO:0003143)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.9 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.8 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.9 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 1.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.8 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.2 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 0.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 0.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 4.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 1.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 6.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 2.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.7 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.6 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 2.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 1.9 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.3 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 2.5 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 1.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.0 1.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.8 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 1.3 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 2.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 2.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 4.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.4 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 1.4 GO:0032418 lysosome localization(GO:0032418)
0.0 5.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 1.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.3 8.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.6 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 0.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 5.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 5.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.4 GO:0035976 AP1 complex(GO:0035976)
0.2 3.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.2 GO:0060077 inhibitory synapse(GO:0060077)
0.1 6.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 5.1 GO:0043218 compact myelin(GO:0043218)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 6.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 1.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 2.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.3 GO:0010369 chromocenter(GO:0010369)
0.0 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.4 GO:0008305 integrin complex(GO:0008305)
0.0 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 1.2 GO:0030057 desmosome(GO:0030057)
0.0 5.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.1 GO:0043034 costamere(GO:0043034)
0.0 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 3.8 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 2.6 GO:0043197 dendritic spine(GO:0043197)
0.0 0.5 GO:1902710 GABA receptor complex(GO:1902710)
0.0 3.8 GO:0044449 contractile fiber part(GO:0044449)
0.0 2.0 GO:0005903 brush border(GO:0005903)
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.3 GO:0031750 D3 dopamine receptor binding(GO:0031750)
1.1 4.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.7 11.9 GO:1990239 steroid hormone binding(GO:1990239)
0.6 3.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 0.9 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.3 1.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 1.8 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3 2.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.9 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 3.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 6.3 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 5.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 3.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.8 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 1.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 3.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.8 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.7 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 2.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 5.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 3.8 GO:0030507 spectrin binding(GO:0030507)
0.0 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 3.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 2.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 4.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 6.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 3.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.1 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 1.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 6.0 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.7 GO:0017048 Rho GTPase binding(GO:0017048)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 8.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 5.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 17.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 6.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 0.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 4.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 3.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 5.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events