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Illumina Body Map 2 (GSE30611)

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Results for SOX10_SOX15

Z-value: 0.73

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Transcription factors associated with SOX10_SOX15

Gene Symbol Gene ID Gene Info
ENSG00000100146.18 SRY-box transcription factor 10
ENSG00000129194.8 SRY-box transcription factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX15hg38_v1_chr17_-_7590072_7590101-0.494.7e-03Click!
SOX10hg38_v1_chr22_-_37984534_37984562-0.281.2e-01Click!

Activity profile of SOX10_SOX15 motif

Sorted Z-values of SOX10_SOX15 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_111542178 3.11 ENST00000283285.10
ENST00000352690.9
CD96 molecule
chr5_+_147878703 2.09 ENST00000296694.5
secretoglobin family 3A member 2
chr17_-_64390592 2.04 ENST00000563523.5
platelet and endothelial cell adhesion molecule 1
chr9_-_71768386 2.02 ENST00000377066.9
ENST00000377044.9
cell migration inducing hyaluronidase 2
chr6_+_113857333 2.02 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr3_+_111542134 1.99 ENST00000438817.6
CD96 molecule
chr2_-_136116165 1.95 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr10_+_6202866 1.73 ENST00000317350.8
ENST00000379785.5
ENST00000625260.2
ENST00000626882.2
ENST00000360521.7
ENST00000379775.9
ENST00000640683.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr2_-_187448244 1.67 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
calcitonin receptor like receptor
chr17_-_64390852 1.64 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr20_-_40689228 1.50 ENST00000373313.3
MAF bZIP transcription factor B
chr2_+_88885397 1.42 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr2_+_231708511 1.36 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
prothymosin alpha
chr18_-_77017042 1.35 ENST00000359645.7
ENST00000397875.7
ENST00000397869.7
ENST00000578193.5
ENST00000578873.5
ENST00000397866.8
ENST00000528160.1
ENST00000527041.1
ENST00000526111.5
ENST00000397865.9
ENST00000382582.7
myelin basic protein
chr12_+_95217760 1.34 ENST00000549002.5
vezatin, adherens junctions transmembrane protein
chr15_+_81000913 1.27 ENST00000267984.4
talin rod domain containing 1
chr12_+_95217792 1.13 ENST00000436874.6
ENST00000551472.5
ENST00000552821.5
vezatin, adherens junctions transmembrane protein
chr4_+_153466324 1.13 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr17_+_4948252 1.09 ENST00000520221.5
enolase 3
chr11_+_110130992 1.08 ENST00000528673.5
zinc finger CCCH-type containing 12C
chr12_-_11269696 1.07 ENST00000381842.7
proline rich protein BstNI subfamily 3
chrX_+_12975216 1.06 ENST00000380635.5
thymosin beta 4 X-linked
chr5_-_157575767 1.04 ENST00000257527.9
ADAM metallopeptidase domain 19
chr4_+_26321192 0.99 ENST00000681484.1
recombination signal binding protein for immunoglobulin kappa J region
chr12_-_11310420 0.98 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr6_-_106975452 0.97 ENST00000619869.1
ENST00000619133.4
CD24 molecule
chr4_+_41612892 0.97 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr12_-_11269805 0.96 ENST00000538488.2
proline rich protein BstNI subfamily 3
chr22_+_22098683 0.95 ENST00000390283.2
immunoglobulin lambda variable 8-61
chr13_-_41019289 0.93 ENST00000239882.7
E74 like ETS transcription factor 1
chr9_-_37025733 0.92 ENST00000651550.1
paired box 5
chr9_-_120714457 0.92 ENST00000373930.4
multiple EGF like domains 9
chr4_+_41612702 0.88 ENST00000509277.5
LIM and calponin homology domains 1
chr11_+_114059702 0.88 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
zinc finger and BTB domain containing 16
chr11_+_114059755 0.87 ENST00000684295.1
zinc finger and BTB domain containing 16
chr7_+_142618821 0.85 ENST00000390393.3
T cell receptor beta variable 19
chr4_+_26321365 0.84 ENST00000505958.6
recombination signal binding protein for immunoglobulin kappa J region
chr5_-_176537361 0.84 ENST00000274811.9
ring finger protein 44
chr5_-_157575741 0.83 ENST00000517905.1
ADAM metallopeptidase domain 19
chr7_+_116672187 0.76 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr8_-_80080816 0.76 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr4_+_2818155 0.75 ENST00000511747.6
SH3 domain binding protein 2
chr6_-_106975309 0.75 ENST00000615659.1
CD24 molecule
chr14_-_50561119 0.73 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr11_-_20160473 0.73 ENST00000524983.3
developing brain homeobox 1
chr3_-_18424533 0.72 ENST00000417717.6
SATB homeobox 1
chr5_+_151026966 0.72 ENST00000520059.1
glutathione peroxidase 3
chr11_+_114060204 0.71 ENST00000683318.1
zinc finger and BTB domain containing 16
chr1_+_66332004 0.68 ENST00000371045.9
ENST00000531025.5
ENST00000526197.5
phosphodiesterase 4B
chr20_-_20712626 0.67 ENST00000202677.12
Ral GTPase activating protein catalytic subunit alpha 2
chr6_-_29559724 0.66 ENST00000377050.5
ubiquitin D
chr3_+_152269103 0.66 ENST00000459747.1
muscleblind like splicing regulator 1
chr1_+_40374648 0.66 ENST00000372708.5
small ArfGAP2
chr7_+_16753731 0.65 ENST00000262067.5
tetraspanin 13
chr13_+_111115303 0.65 ENST00000646102.2
ENST00000449979.5
Rho guanine nucleotide exchange factor 7
chr20_+_36574535 0.65 ENST00000558530.1
ENST00000558028.5
ENST00000611732.4
ENST00000560025.1
TGIF2-RAB5IF readthrough
TGFB induced factor homeobox 2
chr17_+_39653080 0.64 ENST00000443521.1
StAR related lipid transfer domain containing 3
chr5_+_150485813 0.64 ENST00000522491.1
N-deacetylase and N-sulfotransferase 1
chr17_-_78360066 0.63 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chr7_+_114922854 0.63 ENST00000423503.1
ENST00000427207.5
MyoD family inhibitor domain containing
chr12_-_11395556 0.62 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr4_+_118034480 0.62 ENST00000296499.6
N-deacetylase and N-sulfotransferase 3
chr3_+_133400046 0.61 ENST00000302334.3
beaded filament structural protein 2
chr15_+_92883413 0.60 ENST00000629685.2
novel protein
chr2_-_85398734 0.59 ENST00000453973.5
capping actin protein, gelsolin like
chr17_+_38705482 0.59 ENST00000620609.4
MLLT6, PHD finger containing
chr15_-_70096604 0.59 ENST00000559048.5
ENST00000560939.5
ENST00000440567.7
ENST00000557907.5
ENST00000558379.5
ENST00000559929.5
TLE family member 3, transcriptional corepressor
chr10_+_11164961 0.59 ENST00000399850.7
ENST00000417956.6
CUGBP Elav-like family member 2
chr18_+_3450036 0.58 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGFB induced factor homeobox 1
chr3_+_152268920 0.58 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
muscleblind like splicing regulator 1
chr19_+_1249870 0.57 ENST00000591446.6
midnolin
chr6_-_90296824 0.56 ENST00000257749.9
BTB domain and CNC homolog 2
chr12_-_108633864 0.56 ENST00000550948.2
selectin P ligand
chr6_-_63319943 0.56 ENST00000622415.1
ENST00000370658.9
ENST00000485906.6
ENST00000370657.9
lengsin, lens protein with glutamine synthetase domain
chr6_-_127900958 0.56 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
thymocyte selection associated
chr17_-_63699730 0.55 ENST00000578061.5
LIM domain containing 2
chr15_-_52652031 0.55 ENST00000546305.6
family with sequence similarity 214 member A
chr14_-_36521149 0.53 ENST00000518149.5
NK2 homeobox 1
chr1_-_93180261 0.53 ENST00000370280.1
ENST00000479918.5
transmembrane p24 trafficking protein 5
chr1_+_65992389 0.53 ENST00000423207.6
phosphodiesterase 4B
chr7_-_22193728 0.52 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr21_-_5973383 0.52 ENST00000464664.3
novel histone H2B family protein
chr3_+_130440510 0.51 ENST00000373157.8
collagen type VI alpha 5 chain
chr13_-_110307131 0.51 ENST00000543140.6
ENST00000375820.10
collagen type IV alpha 1 chain
chr5_+_31193739 0.51 ENST00000514738.5
cadherin 6
chr8_-_42501224 0.51 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chrX_+_12975083 0.51 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr19_+_10654938 0.51 ENST00000589283.5
interleukin enhancer binding factor 3
chr9_-_72364504 0.51 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chr14_-_102509798 0.51 ENST00000560748.5
ankyrin repeat domain 9
chr6_+_30880962 0.50 ENST00000505534.5
ENST00000503180.5
discoidin domain receptor tyrosine kinase 1
chr11_-_6655788 0.50 ENST00000299441.5
dachsous cadherin-related 1
chr4_+_145482761 0.50 ENST00000507367.1
ENST00000394092.6
ENST00000515385.1
SMAD family member 1
chr6_+_30881051 0.50 ENST00000508317.5
discoidin domain receptor tyrosine kinase 1
chr3_+_141386393 0.50 ENST00000503809.5
zinc finger and BTB domain containing 38
chr17_+_75456618 0.49 ENST00000314256.12
ENST00000582186.5
ENST00000582455.5
ENST00000581252.5
ENST00000579208.5
transmembrane protein 94
chr17_-_78717018 0.49 ENST00000585509.5
cytohesin 1
chr1_-_33349885 0.49 ENST00000373418.7
polyhomeotic homolog 2
chr6_-_46080332 0.48 ENST00000185206.12
chloride intracellular channel 5
chr14_-_94770102 0.48 ENST00000238558.5
goosecoid homeobox
chr17_-_63700100 0.48 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIM domain containing 2
chr17_+_28744034 0.48 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr1_+_215083124 0.47 ENST00000391894.6
potassium two pore domain channel subfamily K member 2
chr16_-_84617547 0.47 ENST00000567786.2
coactosin like F-actin binding protein 1
chr17_-_10549694 0.47 ENST00000622564.4
myosin heavy chain 2
chr11_-_1572261 0.47 ENST00000397374.8
dual specificity phosphatase 8
chr10_-_13707536 0.46 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr13_-_99307387 0.46 ENST00000376414.5
G protein-coupled receptor 183
chr4_+_105146868 0.46 ENST00000380013.9
ENST00000413648.2
tet methylcytosine dioxygenase 2
chr15_+_74782069 0.45 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr5_-_173328053 0.45 ENST00000520648.1
stanniocalcin 2
chr10_+_11165088 0.45 ENST00000608830.5
CUGBP Elav-like family member 2
chr18_-_55351977 0.44 ENST00000643689.1
transcription factor 4
chr11_-_31807617 0.44 ENST00000639920.1
ENST00000640460.1
paired box 6
chr1_+_8945858 0.44 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
carbonic anhydrase 6
chr15_+_74782574 0.44 ENST00000567123.1
ENST00000569462.5
C-terminal Src kinase
chr6_-_106974721 0.44 ENST00000606017.2
ENST00000620405.1
CD24 molecule
chr6_-_90296742 0.44 ENST00000343122.7
ENST00000406998.6
ENST00000453877.5
BTB domain and CNC homolog 2
chr19_+_48469354 0.43 ENST00000452733.7
ENST00000641098.1
cytohesin 2
chr19_+_50203607 0.43 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr3_+_1093002 0.43 ENST00000446702.7
contactin 6
chr10_-_14604389 0.42 ENST00000468747.5
ENST00000378467.8
family with sequence similarity 107 member B
chr9_+_134326435 0.42 ENST00000481739.2
retinoid X receptor alpha
chr6_-_132734692 0.42 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr20_+_6767678 0.42 ENST00000378827.5
bone morphogenetic protein 2
chr17_-_10549652 0.42 ENST00000245503.10
myosin heavy chain 2
chr3_-_48429429 0.41 ENST00000358536.8
plexin B1
chr12_+_103965798 0.41 ENST00000436021.6
thymine DNA glycosylase
chr1_+_32013848 0.41 ENST00000327300.12
ENST00000492989.1
KH RNA binding domain containing, signal transduction associated 1
chr17_+_28744002 0.41 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TNF receptor associated factor 4
chr9_-_35115839 0.41 ENST00000378566.5
ENST00000322813.10
family with sequence similarity 214 member B
chr7_-_151227035 0.41 ENST00000441774.1
ENST00000287844.7
ENST00000222388.6
ATP binding cassette subfamily F member 2
ABCF2-H2BE1 readthrough
chr7_-_112206380 0.40 ENST00000437633.6
ENST00000428084.6
dedicator of cytokinesis 4
chr2_+_180980807 0.40 ENST00000602475.5
ubiquitin conjugating enzyme E2 E3
chr5_-_39425187 0.40 ENST00000545653.5
DAB adaptor protein 2
chrX_+_78747705 0.40 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
lysophosphatidic acid receptor 4
chr5_-_65722094 0.40 ENST00000381007.9
small glutamine rich tetratricopeptide repeat containing beta
chr10_-_14571969 0.40 ENST00000488576.5
ENST00000472095.5
family with sequence similarity 107 member B
chr5_+_43602648 0.40 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr1_-_182391363 0.40 ENST00000417584.6
glutamate-ammonia ligase
chr19_+_10655023 0.39 ENST00000590009.5
interleukin enhancer binding factor 3
chr11_-_119729158 0.39 ENST00000264025.8
nectin cell adhesion molecule 1
chr19_+_13795434 0.39 ENST00000254323.6
zinc finger SWIM-type containing 4
chr7_-_27102669 0.39 ENST00000222718.7
homeobox A2
chr15_-_51751525 0.38 ENST00000454181.6
LysM domain containing 2
chr10_-_73651013 0.38 ENST00000372873.8
synaptopodin 2 like
chr3_-_71304741 0.38 ENST00000484350.5
forkhead box P1
chr7_-_149028651 0.38 ENST00000286091.9
protein disulfide isomerase family A member 4
chr17_+_69502397 0.38 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr4_+_26320975 0.38 ENST00000509158.6
ENST00000681856.1
ENST00000680140.1
ENST00000355476.8
ENST00000680511.1
recombination signal binding protein for immunoglobulin kappa J region
chr17_-_10549612 0.38 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr9_+_131394042 0.38 ENST00000684596.1
ENST00000683519.1
ENST00000682501.1
proline rich coiled-coil 2B
chr1_+_81699665 0.37 ENST00000359929.7
adhesion G protein-coupled receptor L2
chr7_-_149028452 0.37 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr5_-_88785493 0.37 ENST00000503554.4
myocyte enhancer factor 2C
chr13_+_113001758 0.37 ENST00000397024.1
MCF.2 cell line derived transforming sequence like
chr1_+_31413806 0.37 ENST00000536384.2
serine incorporator 2
chr5_-_65723007 0.36 ENST00000506816.1
small glutamine rich tetratricopeptide repeat containing beta
chr5_-_151347552 0.36 ENST00000335244.9
ENST00000521967.1
solute carrier family 36 member 2
chr1_-_204494701 0.36 ENST00000429009.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr5_+_31193678 0.36 ENST00000265071.3
cadherin 6
chr10_+_122163590 0.36 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr14_-_87992838 0.36 ENST00000544807.6
galactosylceramidase
chr22_-_38755458 0.36 ENST00000405510.5
ENST00000433561.5
Sad1 and UNC84 domain containing 2
chr20_-_63956382 0.36 ENST00000358711.7
ENST00000354216.11
uridine-cytidine kinase 1 like 1
chr2_-_157325808 0.36 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ermin
chr21_+_29299368 0.36 ENST00000399921.5
BTB domain and CNC homolog 1
chr22_-_38317423 0.36 ENST00000396832.6
ENST00000403904.5
ENST00000405675.7
casein kinase 1 epsilon
chr22_-_38316973 0.36 ENST00000430335.1
casein kinase 1 epsilon
chr4_-_139556199 0.36 ENST00000274031.8
ENST00000506866.6
SET domain containing 7, histone lysine methyltransferase
chr11_-_89491320 0.35 ENST00000534731.5
ENST00000527626.5
ENST00000525196.5
ENST00000263317.9
NADPH oxidase 4
chr1_-_154178174 0.35 ENST00000302206.9
tropomyosin 3
chr11_-_89491131 0.34 ENST00000343727.9
ENST00000531342.5
ENST00000375979.7
NADPH oxidase 4
chr11_-_44950151 0.34 ENST00000533940.5
ENST00000533937.1
tumor protein p53 inducible protein 11
chr12_-_107760928 0.34 ENST00000547188.1
PR/SET domain 4
chr22_+_19723525 0.34 ENST00000366425.4
glycoprotein Ib platelet subunit beta
chr15_+_62066975 0.34 ENST00000355522.5
C2 calcium dependent domain containing 4A
chr5_+_36606355 0.34 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr10_-_14572313 0.34 ENST00000479731.5
ENST00000468492.5
family with sequence similarity 107 member B
chr5_-_173328407 0.34 ENST00000265087.9
stanniocalcin 2
chr3_-_134373719 0.34 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
angiomotin like 2
chr5_+_72816643 0.34 ENST00000337273.10
ENST00000523768.5
transportin 1
chr18_+_3448456 0.34 ENST00000549780.5
TGFB induced factor homeobox 1
chr17_-_58328756 0.33 ENST00000268893.10
ENST00000343736.9
TSPO associated protein 1
chr8_-_20183090 0.33 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr17_-_39607876 0.33 ENST00000302584.5
neuronal differentiation 2
chr20_-_31723491 0.33 ENST00000676582.1
ENST00000422920.2
BCL2 like 1
chr1_+_43650466 0.32 ENST00000463151.5
lysine demethylase 4A
chr10_-_14572087 0.32 ENST00000482277.5
ENST00000378462.5
family with sequence similarity 107 member B
chr4_-_175812236 0.31 ENST00000505375.5
glycoprotein M6A
chr3_-_120094571 0.31 ENST00000677903.1
glycogen synthase kinase 3 beta
chr2_-_75560893 0.31 ENST00000410113.5
ENST00000393913.8
eva-1 homolog A, regulator of programmed cell death
chr9_-_129824098 0.31 ENST00000351698.5
torsin family 1 member A
chr1_-_113812448 0.31 ENST00000612242.4
ENST00000261441.9
round spermatid basic protein 1
chr19_+_55600277 0.31 ENST00000301073.4
zinc finger protein 524
chr11_+_12674555 0.31 ENST00000527376.3
TEA domain transcription factor 1
chr11_-_89491525 0.31 ENST00000393282.2
NADPH oxidase 4
chr2_+_33458043 0.31 ENST00000437184.5
RAS guanyl releasing protein 3
chr3_-_27484374 0.30 ENST00000445684.5
ENST00000425128.6
solute carrier family 4 member 7
chr19_-_39435627 0.30 ENST00000599705.1
ribosomal protein S16

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.5 2.2 GO:0033606 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.5 3.7 GO:0072011 glomerular endothelium development(GO:0072011)
0.5 1.9 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 2.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 1.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 0.9 GO:0006683 galactosylceramide catabolic process(GO:0006683)
0.2 0.9 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.2 1.3 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 2.3 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 1.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 2.0 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 1.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.5 GO:0003192 mitral valve formation(GO:0003192)
0.2 0.5 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.2 0.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.4 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.6 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 1.7 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.9 GO:2000077 negative regulation of type B pancreatic cell development(GO:2000077)
0.1 1.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.9 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.7 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.5 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.9 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.7 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.6 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.4 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.6 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.3 GO:0060197 cloacal septation(GO:0060197)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.6 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 1.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.1 0.2 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.5 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 1.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.4 GO:0044211 CTP salvage(GO:0044211)
0.0 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.5 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.6 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.6 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.4 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.8 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.6 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 1.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.0 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 1.0 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 1.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.9 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 2.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 1.2 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.0 GO:0032849 regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 2.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 2.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 1.9 GO:0033269 internode region of axon(GO:0033269)
0.1 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 2.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.3 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 3.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 1.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0016590 ACF complex(GO:0016590)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0000322 storage vacuole(GO:0000322)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.5 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.9 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.6 GO:0090543 Flemming body(GO:0090543)
0.0 1.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 3.4 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.7 GO:0097386 glial cell projection(GO:0097386)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 1.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 0.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3 0.9 GO:0004336 galactosylceramidase activity(GO:0004336)
0.2 1.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 0.6 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 1.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 3.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 0.5 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 2.0 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 1.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.3 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 2.3 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.1 0.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.2 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 0.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 2.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.9 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 2.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.8 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 1.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.0 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.0 2.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 2.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 2.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 PID EPO PATHWAY EPO signaling pathway
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 3.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.9 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 3.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 4.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 3.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+