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Illumina Body Map 2 (GSE30611)
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Results for SOX17
Z-value: 1.28
Motif logo
Transcription factors associated with SOX17
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SOX17
|
ENSG00000164736.6 | SRY-box transcription factor 17 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX17 | hg38_v1_chr8_+_54457927_54457943 | -0.18 | 3.3e-01 | Click! |
Activity profile of SOX17 motif
Sorted Z-values of SOX17 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrY_+_2841864 | 7.43 |
ENST00000430575.1
|
RPS4Y1
|
ribosomal protein S4 Y-linked 1 |
| chr12_-_110920568 | 5.58 |
ENST00000548438.1
ENST00000228841.15 |
MYL2
|
myosin light chain 2 |
| chr11_-_118225002 | 2.83 |
ENST00000356289.10
ENST00000526620.5 |
JAML
|
junction adhesion molecule like |
| chr7_+_142352802 | 2.81 |
ENST00000634605.1
|
TRBV7-2
|
T cell receptor beta variable 7-2 |
| chr12_-_110920710 | 2.62 |
ENST00000546404.1
|
MYL2
|
myosin light chain 2 |
| chr11_-_116837586 | 2.58 |
ENST00000375320.5
ENST00000359492.6 ENST00000375329.6 ENST00000375323.5 ENST00000236850.5 |
APOA1
|
apolipoprotein A1 |
| chr13_-_46211841 | 2.23 |
ENST00000442275.1
|
LCP1
|
lymphocyte cytosolic protein 1 |
| chr8_-_17895487 | 2.19 |
ENST00000427924.5
ENST00000381841.4 |
FGL1
|
fibrinogen like 1 |
| chr1_+_40374648 | 2.02 |
ENST00000372708.5
|
SMAP2
|
small ArfGAP2 |
| chr16_+_2817230 | 2.01 |
ENST00000005995.8
ENST00000574813.5 |
PRSS21
|
serine protease 21 |
| chr3_-_52454032 | 1.99 |
ENST00000232975.8
|
TNNC1
|
troponin C1, slow skeletal and cardiac type |
| chrX_-_6535118 | 1.96 |
ENST00000381089.7
ENST00000612369.4 ENST00000398729.1 |
VCX3A
|
variable charge X-linked 3A |
| chr1_-_167090370 | 1.95 |
ENST00000367868.4
|
GPA33
|
glycoprotein A33 |
| chr6_+_54099538 | 1.95 |
ENST00000447836.6
|
MLIP
|
muscular LMNA interacting protein |
| chr14_-_106301848 | 1.85 |
ENST00000390611.2
|
IGHV2-26
|
immunoglobulin heavy variable 2-26 |
| chr3_+_111542178 | 1.84 |
ENST00000283285.10
ENST00000352690.9 |
CD96
|
CD96 molecule |
| chr16_+_33827140 | 1.83 |
ENST00000562905.2
|
IGHV3OR16-13
|
immunoglobulin heavy variable 3/OR16-13 (non-functional) |
| chr8_-_17895403 | 1.81 |
ENST00000381840.5
ENST00000398054.5 |
FGL1
|
fibrinogen like 1 |
| chr6_+_54099565 | 1.79 |
ENST00000511678.5
|
MLIP
|
muscular LMNA interacting protein |
| chrX_+_49331616 | 1.74 |
ENST00000612958.1
|
GAGE13
|
G antigen 13 |
| chrX_+_49341192 | 1.73 |
ENST00000621907.1
|
GAGE2E
|
G antigen 2E |
| chr6_-_49787265 | 1.73 |
ENST00000304801.6
|
PGK2
|
phosphoglycerate kinase 2 |
| chr12_+_101568350 | 1.72 |
ENST00000550514.5
|
MYBPC1
|
myosin binding protein C1 |
| chr5_+_55102635 | 1.67 |
ENST00000274306.7
|
GZMA
|
granzyme A |
| chr1_-_160523204 | 1.65 |
ENST00000368055.1
ENST00000368057.8 ENST00000368059.7 |
SLAMF6
|
SLAM family member 6 |
| chr17_-_66229380 | 1.58 |
ENST00000205948.11
|
APOH
|
apolipoprotein H |
| chr15_+_76336755 | 1.57 |
ENST00000290759.9
|
ISL2
|
ISL LIM homeobox 2 |
| chr1_+_158931539 | 1.57 |
ENST00000368140.6
ENST00000368138.7 ENST00000392254.6 ENST00000392252.7 ENST00000368135.4 |
PYHIN1
|
pyrin and HIN domain family member 1 |
| chr14_-_106557465 | 1.53 |
ENST00000390625.3
|
IGHV3-49
|
immunoglobulin heavy variable 3-49 |
| chr2_+_231592858 | 1.51 |
ENST00000313965.4
|
TEX44
|
testis expressed 44 |
| chr9_-_35650902 | 1.51 |
ENST00000259608.8
ENST00000618781.1 |
SIT1
|
signaling threshold regulating transmembrane adaptor 1 |
| chr2_-_157444044 | 1.50 |
ENST00000264192.8
|
CYTIP
|
cytohesin 1 interacting protein |
| chr11_+_94706412 | 1.47 |
ENST00000299004.13
|
AMOTL1
|
angiomotin like 1 |
| chr14_+_21749163 | 1.46 |
ENST00000390427.3
|
TRAV5
|
T cell receptor alpha variable 5 |
| chr11_+_60396435 | 1.44 |
ENST00000395005.6
|
MS4A14
|
membrane spanning 4-domains A14 |
| chr7_+_142670734 | 1.44 |
ENST00000390398.3
|
TRBV25-1
|
T cell receptor beta variable 25-1 |
| chr4_-_73998669 | 1.43 |
ENST00000296027.5
|
CXCL5
|
C-X-C motif chemokine ligand 5 |
| chr1_+_206897435 | 1.43 |
ENST00000391929.7
ENST00000294984.7 ENST00000611909.4 ENST00000367093.3 |
IL24
|
interleukin 24 |
| chr2_+_181457342 | 1.40 |
ENST00000397033.7
ENST00000233573.6 |
ITGA4
|
integrin subunit alpha 4 |
| chr19_-_19628512 | 1.40 |
ENST00000588461.1
|
LPAR2
|
lysophosphatidic acid receptor 2 |
| chr3_+_158732183 | 1.39 |
ENST00000486568.5
ENST00000495318.5 |
MFSD1
ENSG00000240207.7
|
major facilitator superfamily domain containing 1 novel transcript, antisense to RARRES1 |
| chr22_-_17773976 | 1.38 |
ENST00000317361.11
|
BID
|
BH3 interacting domain death agonist |
| chr3_+_111542134 | 1.38 |
ENST00000438817.6
|
CD96
|
CD96 molecule |
| chr1_+_15617415 | 1.37 |
ENST00000480945.6
|
DDI2
|
DNA damage inducible 1 homolog 2 |
| chr17_-_57745292 | 1.36 |
ENST00000299415.3
|
CCDC182
|
coiled-coil domain containing 182 |
| chr5_-_178187364 | 1.35 |
ENST00000463439.3
|
GMCL2
|
germ cell-less 2, spermatogenesis associated |
| chr19_+_6135635 | 1.35 |
ENST00000588304.5
ENST00000588722.5 ENST00000588485.6 ENST00000591403.5 ENST00000586696.5 ENST00000681525.1 ENST00000589401.5 |
ACSBG2
|
acyl-CoA synthetase bubblegum family member 2 |
| chr1_+_46671821 | 1.35 |
ENST00000334122.5
ENST00000415500.1 |
TEX38
|
testis expressed 38 |
| chr4_-_99144238 | 1.35 |
ENST00000512499.5
ENST00000504125.1 ENST00000505590.5 ENST00000629236.2 ENST00000508393.5 ENST00000265512.12 |
ADH4
|
alcohol dehydrogenase 4 (class II), pi polypeptide |
| chr12_-_10409757 | 1.35 |
ENST00000309384.2
|
KLRC4
|
killer cell lectin like receptor C4 |
| chr1_+_46671871 | 1.32 |
ENST00000564373.1
|
TEX38
|
testis expressed 38 |
| chr14_-_70416973 | 1.32 |
ENST00000555276.5
ENST00000617124.4 |
COX16
SYNJ2BP-COX16
|
cytochrome c oxidase assembly factor COX16 SYNJ2BP-COX16 readthrough |
| chr22_+_22369601 | 1.31 |
ENST00000390295.3
|
IGLV7-46
|
immunoglobulin lambda variable 7-46 |
| chr2_-_89222461 | 1.31 |
ENST00000482769.1
|
IGKV2-28
|
immunoglobulin kappa variable 2-28 |
| chr1_+_84408230 | 1.29 |
ENST00000370662.3
|
DNASE2B
|
deoxyribonuclease 2 beta |
| chr2_+_230225756 | 1.28 |
ENST00000373645.3
|
SP140
|
SP140 nuclear body protein |
| chr14_+_21712313 | 1.27 |
ENST00000390424.2
|
TRAV2
|
T cell receptor alpha variable 2 |
| chr22_-_24555086 | 1.27 |
ENST00000447813.6
ENST00000402766.5 ENST00000435822.6 ENST00000407471.7 |
GUCD1
|
guanylyl cyclase domain containing 1 |
| chr22_-_24555845 | 1.26 |
ENST00000407973.2
|
GUCD1
|
guanylyl cyclase domain containing 1 |
| chr6_-_132757883 | 1.26 |
ENST00000525289.5
ENST00000326499.11 |
VNN2
|
vanin 2 |
| chr7_+_138076453 | 1.24 |
ENST00000242375.8
ENST00000411726.6 |
AKR1D1
|
aldo-keto reductase family 1 member D1 |
| chr7_+_142529268 | 1.22 |
ENST00000612787.1
|
TRBV7-9
|
T cell receptor beta variable 7-9 |
| chrX_-_135799001 | 1.21 |
ENST00000612878.4
|
CT45A6
|
cancer/testis antigen family 45 member A6 |
| chr17_-_38841438 | 1.21 |
ENST00000614158.2
|
C17orf98
|
chromosome 17 open reading frame 98 |
| chr14_+_103563024 | 1.21 |
ENST00000495778.1
|
COA8
|
cytochrome c oxidase assembly factor 8 |
| chr1_+_172452885 | 1.20 |
ENST00000367725.4
|
C1orf105
|
chromosome 1 open reading frame 105 |
| chr14_-_106511856 | 1.20 |
ENST00000390622.2
|
IGHV1-46
|
immunoglobulin heavy variable 1-46 |
| chr19_+_15508517 | 1.20 |
ENST00000269703.8
|
CYP4F22
|
cytochrome P450 family 4 subfamily F member 22 |
| chr1_-_6602885 | 1.18 |
ENST00000377663.3
|
KLHL21
|
kelch like family member 21 |
| chr12_-_389249 | 1.18 |
ENST00000535014.5
ENST00000543507.1 ENST00000544760.1 ENST00000399788.7 |
KDM5A
|
lysine demethylase 5A |
| chr8_-_37940103 | 1.18 |
ENST00000524298.1
ENST00000307599.5 |
GOT1L1
|
glutamic-oxaloacetic transaminase 1 like 1 |
| chrX_+_49322057 | 1.17 |
ENST00000442437.2
|
GAGE12J
|
G antigen 12J |
| chr1_+_174875505 | 1.16 |
ENST00000486220.5
|
RABGAP1L
|
RAB GTPase activating protein 1 like |
| chr3_+_46370854 | 1.14 |
ENST00000292303.4
|
CCR5
|
C-C motif chemokine receptor 5 |
| chrX_-_8171267 | 1.14 |
ENST00000317103.5
|
VCX2
|
variable charge X-linked 2 |
| chr18_+_9885726 | 1.14 |
ENST00000611534.1
ENST00000536353.2 ENST00000584255.1 |
TXNDC2
|
thioredoxin domain containing 2 |
| chr19_+_3933059 | 1.13 |
ENST00000616156.4
ENST00000168977.6 ENST00000599576.5 |
NMRK2
|
nicotinamide riboside kinase 2 |
| chr2_+_90082635 | 1.12 |
ENST00000483379.1
|
IGKV1D-17
|
immunoglobulin kappa variable 1D-17 |
| chr3_-_123992046 | 1.12 |
ENST00000467907.5
ENST00000459660.5 ENST00000495093.1 ENST00000460743.5 ENST00000405845.7 ENST00000484329.1 ENST00000479867.1 ENST00000496145.5 |
ROPN1
|
rhophilin associated tail protein 1 |
| chr14_-_106771020 | 1.12 |
ENST00000617374.2
|
IGHV2-70
|
immunoglobulin heavy variable 2-70 |
| chr22_-_24555920 | 1.11 |
ENST00000621833.4
ENST00000404664.7 |
GUCD1
|
guanylyl cyclase domain containing 1 |
| chr7_+_142587857 | 1.11 |
ENST00000617639.1
|
TRBV14
|
T cell receptor beta variable 14 |
| chr1_+_158831323 | 1.10 |
ENST00000368141.5
|
MNDA
|
myeloid cell nuclear differentiation antigen |
| chr2_-_215138603 | 1.10 |
ENST00000272895.12
|
ABCA12
|
ATP binding cassette subfamily A member 12 |
| chr1_-_92483947 | 1.10 |
ENST00000370332.5
|
GFI1
|
growth factor independent 1 transcriptional repressor |
| chr5_+_111223614 | 1.08 |
ENST00000508074.5
|
CAMK4
|
calcium/calmodulin dependent protein kinase IV |
| chr14_-_54902807 | 1.07 |
ENST00000543643.6
ENST00000536224.2 ENST00000395514.5 ENST00000491895.7 |
GCH1
|
GTP cyclohydrolase 1 |
| chr7_+_138076422 | 1.07 |
ENST00000432161.5
|
AKR1D1
|
aldo-keto reductase family 1 member D1 |
| chr11_-_118252279 | 1.07 |
ENST00000525386.5
ENST00000527472.1 ENST00000278949.9 |
MPZL3
|
myelin protein zero like 3 |
| chr7_-_81770428 | 1.07 |
ENST00000421558.1
|
HGF
|
hepatocyte growth factor |
| chr14_+_22123318 | 1.06 |
ENST00000390455.3
|
TRAV26-1
|
T cell receptor alpha variable 26-1 |
| chr19_+_2163915 | 1.05 |
ENST00000398665.8
|
DOT1L
|
DOT1 like histone lysine methyltransferase |
| chr19_-_15479469 | 1.04 |
ENST00000292609.8
ENST00000340880.5 |
PGLYRP2
|
peptidoglycan recognition protein 2 |
| chr14_-_106724093 | 1.04 |
ENST00000390634.3
|
IGHV2-70D
|
immunoglobulin heavy variable 2-70D |
| chr14_+_21825453 | 1.03 |
ENST00000390432.2
|
TRAV10
|
T cell receptor alpha variable 10 |
| chr1_-_153945225 | 1.03 |
ENST00000368646.6
|
DENND4B
|
DENN domain containing 4B |
| chr6_+_31572279 | 1.02 |
ENST00000418386.3
|
LTA
|
lymphotoxin alpha |
| chr2_-_89040745 | 1.02 |
ENST00000480492.1
|
IGKV1-12
|
immunoglobulin kappa variable 1-12 |
| chr2_+_181457198 | 1.02 |
ENST00000339307.8
|
ITGA4
|
integrin subunit alpha 4 |
| chr10_-_125683106 | 1.02 |
ENST00000532135.5
ENST00000526819.5 |
TEX36
|
testis expressed 36 |
| chr14_+_22202561 | 1.01 |
ENST00000390460.1
|
TRAV26-2
|
T cell receptor alpha variable 26-2 |
| chr7_-_117427487 | 1.01 |
ENST00000284629.7
|
ASZ1
|
ankyrin repeat, SAM and basic leucine zipper domain containing 1 |
| chr12_+_69348372 | 1.01 |
ENST00000261267.7
ENST00000549690.1 ENST00000548839.1 |
LYZ
|
lysozyme |
| chr19_+_43716095 | 1.00 |
ENST00000596627.1
|
IRGC
|
immunity related GTPase cinema |
| chr10_+_22321056 | 0.99 |
ENST00000376663.8
|
BMI1
|
BMI1 proto-oncogene, polycomb ring finger |
| chr1_-_197775633 | 0.99 |
ENST00000422998.1
|
DENND1B
|
DENN domain containing 1B |
| chr19_+_16661121 | 0.98 |
ENST00000187762.7
ENST00000599479.1 |
TMEM38A
|
transmembrane protein 38A |
| chr3_-_123991352 | 0.98 |
ENST00000184183.8
|
ROPN1
|
rhophilin associated tail protein 1 |
| chr11_+_60378524 | 0.97 |
ENST00000530614.5
ENST00000530027.5 ENST00000300184.8 ENST00000530234.2 ENST00000528215.1 ENST00000531787.5 |
MS4A7
MS4A14
|
membrane spanning 4-domains A7 membrane spanning 4-domains A14 |
| chr10_-_125683155 | 0.96 |
ENST00000368821.4
|
TEX36
|
testis expressed 36 |
| chr19_+_54593619 | 0.96 |
ENST00000251372.8
ENST00000453777.1 |
LILRA1
|
leukocyte immunoglobulin like receptor A1 |
| chr6_+_83859640 | 0.95 |
ENST00000369679.4
ENST00000369681.10 |
CYB5R4
|
cytochrome b5 reductase 4 |
| chr12_+_10010627 | 0.95 |
ENST00000338896.11
ENST00000396502.5 |
CLEC12B
|
C-type lectin domain family 12 member B |
| chr1_+_207496229 | 0.95 |
ENST00000367051.6
ENST00000367053.6 ENST00000367052.6 |
CR1
|
complement C3b/C4b receptor 1 (Knops blood group) |
| chr7_-_122304738 | 0.94 |
ENST00000442488.7
|
FEZF1
|
FEZ family zinc finger 1 |
| chr16_+_31355215 | 0.94 |
ENST00000562522.2
|
ITGAX
|
integrin subunit alpha X |
| chr8_-_7452365 | 0.94 |
ENST00000458665.5
ENST00000528168.3 |
SPAG11B
|
sperm associated antigen 11B |
| chr2_+_102418642 | 0.94 |
ENST00000264260.6
|
IL18RAP
|
interleukin 18 receptor accessory protein |
| chr21_+_29300111 | 0.93 |
ENST00000451655.5
|
BACH1
|
BTB domain and CNC homolog 1 |
| chr15_-_19988117 | 0.93 |
ENST00000558565.2
|
IGHV3OR15-7
|
immunoglobulin heavy variable 3/OR15-7 (pseudogene) |
| chr19_+_15010720 | 0.93 |
ENST00000292574.4
|
CCDC105
|
coiled-coil domain containing 105 |
| chr19_+_43716070 | 0.91 |
ENST00000244314.6
|
IRGC
|
immunity related GTPase cinema |
| chr2_+_43838963 | 0.89 |
ENST00000272286.4
|
ABCG8
|
ATP binding cassette subfamily G member 8 |
| chr2_-_89117844 | 0.89 |
ENST00000490686.1
|
IGKV1-17
|
immunoglobulin kappa variable 1-17 |
| chr9_+_132978687 | 0.89 |
ENST00000372122.4
ENST00000372123.5 |
GFI1B
|
growth factor independent 1B transcriptional repressor |
| chrX_+_8464830 | 0.88 |
ENST00000453306.4
ENST00000381032.6 ENST00000444481.3 |
VCX3B
|
variable charge X-linked 3B |
| chr14_-_105065422 | 0.88 |
ENST00000329797.8
ENST00000539291.6 ENST00000392585.2 |
GPR132
|
G protein-coupled receptor 132 |
| chr1_-_6602859 | 0.88 |
ENST00000377658.8
|
KLHL21
|
kelch like family member 21 |
| chr3_+_125969172 | 0.88 |
ENST00000514116.6
ENST00000513830.5 |
ROPN1B
|
rhophilin associated tail protein 1B |
| chr2_+_210477708 | 0.87 |
ENST00000673711.1
|
CPS1
|
carbamoyl-phosphate synthase 1 |
| chr19_+_54630497 | 0.86 |
ENST00000396332.8
ENST00000427581.6 |
LILRB1
|
leukocyte immunoglobulin like receptor B1 |
| chr3_-_15498548 | 0.86 |
ENST00000605797.1
|
COLQ
|
collagen like tail subunit of asymmetric acetylcholinesterase |
| chr6_+_31571957 | 0.86 |
ENST00000454783.5
|
LTA
|
lymphotoxin alpha |
| chr1_+_207496268 | 0.86 |
ENST00000529814.1
|
CR1
|
complement C3b/C4b receptor 1 (Knops blood group) |
| chr2_+_90172802 | 0.86 |
ENST00000390277.3
|
IGKV3D-11
|
immunoglobulin kappa variable 3D-11 |
| chr8_-_51809414 | 0.85 |
ENST00000356297.5
|
PXDNL
|
peroxidasin like |
| chr10_+_128047406 | 0.85 |
ENST00000467366.1
|
PTPRE
|
protein tyrosine phosphatase receptor type E |
| chr3_+_125969214 | 0.84 |
ENST00000508088.1
|
ROPN1B
|
rhophilin associated tail protein 1B |
| chr2_-_88947820 | 0.84 |
ENST00000496168.1
|
IGKV1-5
|
immunoglobulin kappa variable 1-5 |
| chr2_+_90004792 | 0.83 |
ENST00000462693.1
|
IGKV2D-24
|
immunoglobulin kappa variable 2D-24 (non-functional) |
| chr3_+_98732688 | 0.83 |
ENST00000486334.6
ENST00000394162.5 ENST00000613264.4 |
ST3GAL6
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| chr19_-_4902854 | 0.82 |
ENST00000381781.2
|
ARRDC5
|
arrestin domain containing 5 |
| chr15_-_72272999 | 0.82 |
ENST00000568360.5
|
PARP6
|
poly(ADP-ribose) polymerase family member 6 |
| chr5_+_76875177 | 0.82 |
ENST00000613039.1
|
S100Z
|
S100 calcium binding protein Z |
| chr1_+_197912462 | 0.82 |
ENST00000475727.1
ENST00000367391.5 ENST00000367390.7 |
LHX9
|
LIM homeobox 9 |
| chrX_-_135764444 | 0.81 |
ENST00000597510.6
|
CT45A3
|
cancer/testis antigen family 45 member A3 |
| chr14_+_20768393 | 0.80 |
ENST00000326783.4
|
EDDM3B
|
epididymal protein 3B |
| chr22_+_44181357 | 0.80 |
ENST00000417767.1
|
PARVG
|
parvin gamma |
| chr2_-_37188670 | 0.80 |
ENST00000535679.6
|
SULT6B1
|
sulfotransferase family 6B member 1 |
| chr11_+_57542641 | 0.80 |
ENST00000527972.5
ENST00000399154.3 |
SMTNL1
|
smoothelin like 1 |
| chr18_+_24460655 | 0.80 |
ENST00000426880.2
|
HRH4
|
histamine receptor H4 |
| chrY_-_24047969 | 0.79 |
ENST00000306882.4
ENST00000382407.1 |
CDY1B
|
chromodomain Y-linked 1B |
| chr11_-_123885627 | 0.79 |
ENST00000528595.1
ENST00000375026.7 |
TMEM225
|
transmembrane protein 225 |
| chr14_-_106235582 | 0.78 |
ENST00000390607.2
|
IGHV3-21
|
immunoglobulin heavy variable 3-21 |
| chrX_-_135781729 | 0.78 |
ENST00000617203.1
|
CT45A5
|
cancer/testis antigen family 45 member A5 |
| chrY_-_17880220 | 0.78 |
ENST00000382867.4
|
CDY2B
|
chromodomain Y-linked 2B |
| chr19_+_41576206 | 0.78 |
ENST00000187608.13
|
CEACAM21
|
CEA cell adhesion molecule 21 |
| chr1_+_207496147 | 0.78 |
ENST00000400960.7
ENST00000367049.9 |
CR1
|
complement C3b/C4b receptor 1 (Knops blood group) |
| chr4_-_69495897 | 0.77 |
ENST00000305107.7
ENST00000639621.1 |
UGT2B4
|
UDP glucuronosyltransferase family 2 member B4 |
| chr9_-_136748515 | 0.77 |
ENST00000341206.9
|
LCN6
|
lipocalin 6 |
| chr7_+_139829242 | 0.77 |
ENST00000455353.6
ENST00000458722.6 ENST00000448866.7 ENST00000411653.6 |
TBXAS1
|
thromboxane A synthase 1 |
| chr3_+_98732430 | 0.77 |
ENST00000497008.5
|
ST3GAL6
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| chr5_-_16508858 | 0.77 |
ENST00000684456.1
|
RETREG1
|
reticulophagy regulator 1 |
| chr19_+_3933581 | 0.76 |
ENST00000593949.1
|
NMRK2
|
nicotinamide riboside kinase 2 |
| chr1_+_202214072 | 0.75 |
ENST00000439764.2
|
LGR6
|
leucine rich repeat containing G protein-coupled receptor 6 |
| chr2_+_227325151 | 0.75 |
ENST00000423098.5
|
MFF
|
mitochondrial fission factor |
| chr19_+_41376560 | 0.73 |
ENST00000436170.6
|
TMEM91
|
transmembrane protein 91 |
| chr1_+_222739670 | 0.73 |
ENST00000456298.5
|
FAM177B
|
family with sequence similarity 177 member B |
| chr12_+_8992029 | 0.73 |
ENST00000543895.1
|
KLRG1
|
killer cell lectin like receptor G1 |
| chr6_+_88047822 | 0.72 |
ENST00000237201.2
|
SPACA1
|
sperm acrosome associated 1 |
| chr2_-_88992903 | 0.72 |
ENST00000495489.1
|
IGKV1-8
|
immunoglobulin kappa variable 1-8 |
| chr5_-_55692620 | 0.72 |
ENST00000503817.5
ENST00000512595.5 |
SLC38A9
|
solute carrier family 38 member 9 |
| chr9_-_94328644 | 0.72 |
ENST00000341207.5
ENST00000253262.9 |
NUTM2F
|
NUT family member 2F |
| chr17_-_74531467 | 0.71 |
ENST00000314401.3
ENST00000392621.6 |
CD300LB
|
CD300 molecule like family member b |
| chr5_-_16508990 | 0.71 |
ENST00000399793.6
|
RETREG1
|
reticulophagy regulator 1 |
| chr19_+_54769785 | 0.71 |
ENST00000336077.11
|
KIR2DL1
|
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 |
| chr13_-_46182136 | 0.70 |
ENST00000323076.7
|
LCP1
|
lymphocyte cytosolic protein 1 |
| chr17_-_4949037 | 0.70 |
ENST00000572383.1
|
PFN1
|
profilin 1 |
| chr4_-_69495861 | 0.69 |
ENST00000512583.5
|
UGT2B4
|
UDP glucuronosyltransferase family 2 member B4 |
| chr10_+_11005301 | 0.68 |
ENST00000416382.6
ENST00000631460.1 ENST00000631816.1 |
CELF2
|
CUGBP Elav-like family member 2 |
| chr19_+_34404379 | 0.68 |
ENST00000246535.4
|
PDCD2L
|
programmed cell death 2 like |
| chr4_+_68815991 | 0.67 |
ENST00000265403.12
ENST00000458688.2 |
UGT2B10
|
UDP glucuronosyltransferase family 2 member B10 |
| chr19_+_41376692 | 0.67 |
ENST00000447302.6
ENST00000544232.5 ENST00000542945.5 ENST00000540732.3 |
TMEM91
ENSG00000255730.5
|
transmembrane protein 91 novel protein |
| chr17_-_74361860 | 0.67 |
ENST00000375366.4
|
BTBD17
|
BTB domain containing 17 |
| chrX_-_135868069 | 0.66 |
ENST00000604569.1
|
CT45A9
|
cancer/testis antigen family 45 member A9 |
| chr11_+_60378494 | 0.66 |
ENST00000534016.5
|
MS4A7
|
membrane spanning 4-domains A7 |
| chr3_+_98732236 | 0.65 |
ENST00000265261.10
ENST00000483910.5 ENST00000460774.5 |
ST3GAL6
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| chr3_-_45958654 | 0.65 |
ENST00000438446.1
|
FYCO1
|
FYVE and coiled-coil domain autophagy adaptor 1 |
| chr2_+_86441341 | 0.63 |
ENST00000312912.10
ENST00000409064.5 |
KDM3A
|
lysine demethylase 3A |
| chr12_-_124914056 | 0.63 |
ENST00000541272.1
ENST00000535131.1 |
UBC
|
ubiquitin C |
| chr20_-_63568074 | 0.62 |
ENST00000427522.6
|
HELZ2
|
helicase with zinc finger 2 |
| chr6_-_31357171 | 0.62 |
ENST00000412585.7
ENST00000434333.1 |
HLA-B
|
major histocompatibility complex, class I, B |
| chr5_+_139342442 | 0.61 |
ENST00000394795.6
ENST00000510080.1 |
PAIP2
|
poly(A) binding protein interacting protein 2 |
| chrX_-_135850791 | 0.61 |
ENST00000611438.1
|
CT45A8
|
cancer/testis antigen family 45 member A8 |
| chr7_-_115968302 | 0.61 |
ENST00000457268.5
|
TFEC
|
transcription factor EC |
| chr17_-_59964714 | 0.61 |
ENST00000589113.1
ENST00000305783.13 |
RNFT1
|
ring finger protein, transmembrane 1 |
| chr1_-_145995713 | 0.61 |
ENST00000425134.2
|
TXNIP
|
thioredoxin interacting protein |
| chr17_-_5234801 | 0.60 |
ENST00000571800.5
ENST00000574081.6 ENST00000399600.8 ENST00000574297.1 |
SCIMP
|
SLP adaptor and CSK interacting membrane protein |
| chr1_+_13254212 | 0.60 |
ENST00000622421.2
|
PRAMEF5
|
PRAME family member 5 |
| chr22_+_44069043 | 0.59 |
ENST00000404989.1
|
PARVB
|
parvin beta |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX17
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.2 | GO:0002728 | negative regulation of natural killer cell cytokine production(GO:0002728) |
| 0.9 | 2.6 | GO:0045957 | regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957) |
| 0.7 | 2.6 | GO:0035853 | chromosome passenger complex localization to spindle midzone(GO:0035853) |
| 0.6 | 8.2 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.6 | 1.9 | GO:0002876 | positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876) |
| 0.6 | 1.7 | GO:0002769 | natural killer cell inhibitory signaling pathway(GO:0002769) |
| 0.5 | 1.6 | GO:0021524 | visceral motor neuron differentiation(GO:0021524) |
| 0.5 | 2.6 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 0.5 | 2.0 | GO:0032972 | diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972) |
| 0.5 | 1.5 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
| 0.5 | 1.5 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 0.5 | 2.4 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.5 | 2.3 | GO:0030573 | bile acid catabolic process(GO:0030573) |
| 0.4 | 1.2 | GO:0006532 | aspartate biosynthetic process(GO:0006532) |
| 0.4 | 1.1 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 0.4 | 1.1 | GO:0002372 | myeloid dendritic cell cytokine production(GO:0002372) |
| 0.4 | 1.1 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
| 0.3 | 1.0 | GO:0032827 | negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) |
| 0.3 | 1.0 | GO:0003032 | detection of oxygen(GO:0003032) |
| 0.3 | 2.8 | GO:0035696 | monocyte extravasation(GO:0035696) |
| 0.3 | 0.9 | GO:1903718 | carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718) |
| 0.3 | 0.8 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.3 | 1.0 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.2 | 0.9 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 0.2 | 1.1 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.2 | 0.9 | GO:2001193 | gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193) |
| 0.2 | 1.2 | GO:0034721 | negative regulation of histone deacetylation(GO:0031064) histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 0.2 | 1.5 | GO:0061709 | reticulophagy(GO:0061709) |
| 0.2 | 0.5 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.2 | 0.6 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 0.2 | 0.5 | GO:0030974 | thiamine pyrophosphate transport(GO:0030974) |
| 0.2 | 0.9 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.1 | 0.7 | GO:1990523 | bone regeneration(GO:1990523) |
| 0.1 | 0.9 | GO:0006581 | acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) |
| 0.1 | 1.6 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.1 | 0.5 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.1 | 1.0 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 0.5 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 0.1 | 2.9 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 1.1 | GO:0019064 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 0.1 | 1.7 | GO:0032071 | regulation of endodeoxyribonuclease activity(GO:0032071) negative regulation of nuclease activity(GO:0032074) |
| 0.1 | 0.7 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 0.1 | 1.0 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 1.7 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.1 | 0.5 | GO:0070173 | regulation of enamel mineralization(GO:0070173) |
| 0.1 | 0.3 | GO:0036451 | cap mRNA methylation(GO:0036451) |
| 0.1 | 8.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 0.9 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.1 | 1.4 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.1 | 0.5 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 0.1 | 1.1 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.1 | 0.3 | GO:0061182 | negative regulation of chondrocyte development(GO:0061182) |
| 0.1 | 1.1 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 0.1 | 0.3 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.1 | 1.6 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
| 0.1 | 1.7 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.1 | 1.3 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 1.3 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.1 | 0.4 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.1 | 1.4 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.1 | 0.4 | GO:0098704 | fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.1 | 2.2 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
| 0.1 | 0.6 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.1 | 0.5 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.1 | 0.3 | GO:0019856 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
| 0.1 | 6.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.1 | 0.6 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.1 | 2.3 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.1 | 0.2 | GO:1903383 | neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) |
| 0.1 | 2.2 | GO:0071354 | cellular response to interleukin-6(GO:0071354) |
| 0.1 | 0.4 | GO:1903433 | regulation of constitutive secretory pathway(GO:1903433) |
| 0.0 | 7.9 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.4 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.0 | 0.5 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.0 | 0.4 | GO:1900045 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.0 | 1.0 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.0 | 0.4 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 0.0 | 1.4 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.0 | 0.3 | GO:0045007 | depurination(GO:0045007) |
| 0.0 | 1.4 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.8 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.0 | 4.0 | GO:0030317 | sperm motility(GO:0030317) |
| 0.0 | 0.5 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.0 | 0.7 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.0 | 0.2 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.0 | 0.8 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.0 | 0.2 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.0 | 1.0 | GO:0007379 | segment specification(GO:0007379) |
| 0.0 | 0.6 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.0 | 0.1 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.0 | 1.1 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.0 | 1.0 | GO:0035745 | CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745) |
| 0.0 | 0.3 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 1.4 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.0 | 0.3 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 0.0 | 0.5 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.6 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.0 | 1.4 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.2 | GO:0060011 | progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.1 | GO:0070145 | mitochondrial asparaginyl-tRNA aminoacylation(GO:0070145) |
| 0.0 | 0.3 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.0 | 1.4 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 4.5 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 0.4 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 0.6 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.0 | 0.6 | GO:0002347 | response to tumor cell(GO:0002347) |
| 0.0 | 1.8 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
| 0.0 | 2.1 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.8 | GO:0050427 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.4 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.0 | 0.8 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.0 | 0.1 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.0 | 0.1 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
| 0.0 | 0.1 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.5 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.8 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.0 | 0.2 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.2 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.0 | 1.5 | GO:0034113 | heterotypic cell-cell adhesion(GO:0034113) |
| 0.0 | 0.2 | GO:0060613 | fat pad development(GO:0060613) |
| 0.0 | 0.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 0.1 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.0 | 0.2 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.0 | 0.7 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 0.2 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.0 | 0.3 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.5 | GO:0010390 | histone monoubiquitination(GO:0010390) |
| 0.0 | 0.7 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.0 | GO:0031455 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.0 | 0.6 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.0 | 0.1 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
| 0.0 | 0.2 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 2.0 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.6 | 2.6 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.5 | 2.4 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.5 | 8.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.3 | 3.1 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.3 | 3.9 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 1.1 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.1 | 8.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 1.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 1.5 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 1.2 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.1 | 1.0 | GO:0071546 | pi-body(GO:0071546) |
| 0.1 | 0.4 | GO:0071547 | piP-body(GO:0071547) |
| 0.1 | 0.4 | GO:0097182 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.1 | 1.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.1 | 0.5 | GO:0005713 | recombination nodule(GO:0005713) |
| 0.1 | 7.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 0.3 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) NF-kappaB complex(GO:0071159) |
| 0.1 | 1.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 1.1 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 0.7 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.1 | 0.9 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 0.4 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.1 | 2.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.7 | GO:0032982 | myosin filament(GO:0032982) |
| 0.1 | 0.6 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 0.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 1.0 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 1.0 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 0.6 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.0 | 0.2 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.0 | 0.2 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 0.0 | 4.0 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 2.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.6 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 1.0 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.3 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.0 | 1.9 | GO:0032592 | integral component of mitochondrial membrane(GO:0032592) |
| 0.0 | 4.3 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.1 | GO:0035363 | histone locus body(GO:0035363) |
| 0.0 | 0.5 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.6 | GO:0098553 | integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.0 | 2.9 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 1.2 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 1.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.2 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.0 | 0.6 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.4 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.8 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 1.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.3 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.0 | 1.3 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 1.0 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.6 | GO:0004877 | complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877) |
| 0.6 | 1.7 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.5 | 3.7 | GO:0034191 | apolipoprotein A-I receptor binding(GO:0034191) |
| 0.5 | 1.9 | GO:0061769 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 0.5 | 2.3 | GO:0047787 | delta4-3-oxosteroid 5beta-reductase activity(GO:0047787) |
| 0.4 | 2.2 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.4 | 1.3 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.4 | 1.2 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.3 | 8.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.3 | 1.3 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.3 | 2.4 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.3 | 1.6 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.3 | 1.0 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) |
| 0.3 | 0.8 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 0.2 | 1.3 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.2 | 0.9 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.2 | 0.9 | GO:0030107 | HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) |
| 0.2 | 2.0 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.2 | 1.2 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.2 | 0.5 | GO:0090422 | thiamine pyrophosphate transporter activity(GO:0090422) |
| 0.1 | 0.5 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.1 | 1.1 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.1 | 1.4 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.1 | 8.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 1.0 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.1 | 0.4 | GO:0034584 | piRNA binding(GO:0034584) |
| 0.1 | 1.1 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.1 | 0.5 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.1 | 0.3 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.1 | 1.7 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.1 | 0.4 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.1 | 0.3 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.1 | 1.4 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 0.3 | GO:0032406 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.1 | 0.2 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) cholestenol delta-isomerase activity(GO:0047750) |
| 0.1 | 6.8 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 1.0 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.1 | 1.1 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.1 | 0.4 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.1 | 1.4 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.5 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.1 | 0.6 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.1 | 1.2 | GO:0010857 | calcium-dependent protein kinase activity(GO:0010857) |
| 0.1 | 0.5 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 11.5 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 0.7 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 1.7 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.0 | 0.3 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 0.0 | 0.9 | GO:0030547 | receptor inhibitor activity(GO:0030547) |
| 0.0 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.6 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.0 | 0.6 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.0 | 0.9 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.3 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.0 | 0.2 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.0 | 0.5 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 2.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.2 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.0 | 2.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.4 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.8 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 0.9 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.9 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.0 | 0.3 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.0 | 0.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 0.3 | GO:0016416 | O-palmitoyltransferase activity(GO:0016416) |
| 0.0 | 1.0 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 1.3 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.6 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 2.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.7 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 0.1 | GO:0050560 | aspartate-tRNA ligase activity(GO:0004815) aspartate-tRNA(Asn) ligase activity(GO:0050560) |
| 0.0 | 1.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.2 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.0 | 1.1 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.3 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 0.0 | 0.1 | GO:0039552 | RIG-I binding(GO:0039552) |
| 0.0 | 0.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.5 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 5.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 1.0 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.1 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.0 | 0.4 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.4 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.0 | 0.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.2 | GO:0050544 | arachidonic acid binding(GO:0050544) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 8.2 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 2.4 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 2.8 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 1.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 2.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.5 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 0.7 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 1.9 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.7 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.8 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 1.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 1.0 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 1.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.2 | 4.6 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.2 | 11.9 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 2.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 7.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 2.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 1.3 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 0.6 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.1 | 2.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.6 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 1.1 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 5.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.5 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 1.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.6 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.5 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.7 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 1.4 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.7 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.3 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 0.6 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 1.1 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.0 | 0.3 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 0.6 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.4 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 1.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.2 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |