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Illumina Body Map 2 (GSE30611)

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Results for SOX18

Z-value: 0.86

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Transcription factors associated with SOX18

Gene Symbol Gene ID Gene Info
ENSG00000203883.7 SRY-box transcription factor 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX18hg38_v1_chr20_-_64049631_64049646-0.241.9e-01Click!

Activity profile of SOX18 motif

Sorted Z-values of SOX18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_137499293 1.57 ENST00000510689.5
ENST00000394945.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
chr3_+_111998739 1.29 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr1_-_156248084 1.18 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr14_+_22070548 1.00 ENST00000390450.3
T cell receptor alpha variable 22
chr3_+_19148500 1.00 ENST00000328405.7
potassium voltage-gated channel subfamily H member 8
chr5_+_157180816 1.00 ENST00000422843.8
IL2 inducible T cell kinase
chr1_-_156248038 0.99 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr1_-_156248013 0.96 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr12_+_15322529 0.94 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr3_+_111998915 0.93 ENST00000478951.6
transgelin 3
chr15_-_79090760 0.93 ENST00000419573.7
ENST00000558480.7
Ras protein specific guanine nucleotide releasing factor 1
chr5_-_147081428 0.90 ENST00000394413.7
protein phosphatase 2 regulatory subunit Bbeta
chr12_-_10409757 0.88 ENST00000309384.2
killer cell lectin like receptor C4
chr12_-_10435940 0.88 ENST00000381901.5
ENST00000381902.7
ENST00000539033.1
killer cell lectin like receptor C2
novel protein
chr13_-_28100556 0.86 ENST00000241453.12
fms related receptor tyrosine kinase 3
chr1_+_209756032 0.84 ENST00000400959.7
ENST00000367025.8
TRAF3 interacting protein 3
chr4_+_69096494 0.82 ENST00000508661.5
ENST00000622664.1
UDP glucuronosyltransferase family 2 member B7
chr3_+_186717348 0.82 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr12_-_10420550 0.81 ENST00000381903.2
ENST00000396439.7
killer cell lectin like receptor C3
chrM_+_8366 0.81 ENST00000361851.1
mitochondrially encoded ATP synthase membrane subunit 8
chr2_+_233712905 0.80 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr1_+_160081529 0.79 ENST00000368088.4
potassium inwardly rectifying channel subfamily J member 9
chr7_+_142352802 0.79 ENST00000634605.1
T cell receptor beta variable 7-2
chr12_-_75209701 0.78 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr1_-_230745574 0.78 ENST00000681269.1
angiotensinogen
chr4_+_42397473 0.77 ENST00000319234.5
shisa family member 3
chr12_-_75209814 0.76 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chr14_+_21868822 0.75 ENST00000390436.2
T cell receptor alpha variable 13-1
chr1_+_209756149 0.75 ENST00000367026.7
TRAF3 interacting protein 3
chr6_+_24126186 0.72 ENST00000378478.5
ENST00000378491.9
ENST00000378477.2
neurensin 1
chr5_-_147081462 0.69 ENST00000508267.5
ENST00000504198.5
protein phosphatase 2 regulatory subunit Bbeta
chr12_+_861124 0.69 ENST00000676347.1
WNK lysine deficient protein kinase 1
chr5_-_142644201 0.65 ENST00000394496.2
ENST00000610990.4
fibroblast growth factor 1
chr17_-_40885232 0.64 ENST00000167588.4
keratin 20
chr1_-_157777124 0.64 ENST00000361516.8
ENST00000368181.4
Fc receptor like 2
chr4_+_69096467 0.63 ENST00000305231.12
UDP glucuronosyltransferase family 2 member B7
chr7_+_142511614 0.62 ENST00000390377.1
T cell receptor beta variable 7-7
chr1_-_119811458 0.62 ENST00000256585.10
ENST00000354219.5
ENST00000369401.4
regenerating family member 4
chr13_-_51845169 0.61 ENST00000627246.3
ENST00000629372.3
transmembrane protein 272
chr12_-_110445540 0.60 ENST00000547365.1
actin related protein 2/3 complex subunit 3
chr2_-_37672178 0.60 ENST00000457889.1
CDC42 effector protein 3
chr3_+_124384757 0.58 ENST00000684374.1
kalirin RhoGEF kinase
chr19_+_19238259 0.58 ENST00000588231.1
neurocan
chr17_-_78723556 0.57 ENST00000587308.5
cytohesin 1
chr12_-_663572 0.56 ENST00000662884.1
ninjurin 2
chr3_-_24495532 0.55 ENST00000643772.1
ENST00000642307.1
ENST00000645139.1
thyroid hormone receptor beta
chr11_-_89490715 0.55 ENST00000528341.5
NADPH oxidase 4
chr11_-_89491131 0.54 ENST00000343727.9
ENST00000531342.5
ENST00000375979.7
NADPH oxidase 4
chr2_+_79025696 0.54 ENST00000272324.10
regenerating family member 3 gamma
chr4_-_173399102 0.53 ENST00000296506.8
stimulator of chondrogenesis 1
chr7_-_36724380 0.53 ENST00000617267.4
acyloxyacyl hydrolase
chr2_+_44275457 0.53 ENST00000611973.4
ENST00000409387.5
solute carrier family 3 member 1
chr11_+_73647645 0.53 ENST00000545798.5
ENST00000539157.5
ENST00000546251.5
ENST00000535582.5
ENST00000538227.5
pleckstrin homology domain containing B1
chr14_+_22422371 0.52 ENST00000390469.2
T cell receptor delta variable 2
chr13_-_51845136 0.52 ENST00000626362.3
transmembrane protein 272
chr9_-_134917872 0.52 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr11_-_105023136 0.52 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr19_-_50639827 0.51 ENST00000593901.5
ENST00000600079.6
synaptotagmin 3
chr2_+_79025678 0.51 ENST00000393897.6
regenerating family member 3 gamma
chr2_-_37671633 0.50 ENST00000295324.4
CDC42 effector protein 3
chr2_+_209653171 0.50 ENST00000447185.5
microtubule associated protein 2
chr3_+_68006224 0.50 ENST00000496687.1
TAFA chemokine like family member 1
chr7_+_142529268 0.50 ENST00000612787.1
T cell receptor beta variable 7-9
chr1_-_182391783 0.49 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chr2_+_79025709 0.48 ENST00000409471.1
regenerating family member 3 gamma
chr5_-_67196791 0.47 ENST00000256447.5
CD180 molecule
chr1_+_179954740 0.47 ENST00000491495.2
ENST00000367607.8
centrosomal protein 350
chr11_+_73648889 0.47 ENST00000542389.5
pleckstrin homology domain containing B1
chr11_+_13277639 0.46 ENST00000527998.5
ENST00000529388.6
ENST00000401424.6
ENST00000403510.8
ENST00000403290.6
ENST00000533520.5
ENST00000389707.8
ENST00000673817.1
aryl hydrocarbon receptor nuclear translocator like
chr7_-_123199960 0.46 ENST00000194130.7
solute carrier family 13 member 1
chr3_+_124384772 0.46 ENST00000682575.1
kalirin RhoGEF kinase
chr12_-_95996302 0.45 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr12_-_262828 0.45 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
solute carrier family 6 member 13
chr12_-_75209422 0.44 ENST00000393288.2
ENST00000540018.5
potassium voltage-gated channel subfamily C member 2
chrX_-_149505274 0.44 ENST00000428056.6
ENST00000340855.11
ENST00000370441.8
iduronate 2-sulfatase
chr1_-_182391363 0.44 ENST00000417584.6
glutamate-ammonia ligase
chr10_+_88759997 0.43 ENST00000404459.2
lipase family member N
chr17_-_75855204 0.42 ENST00000589642.5
ENST00000593002.1
ENST00000590221.5
ENST00000587374.5
ENST00000585462.5
ENST00000254806.8
ENST00000433525.6
ENST00000626827.2
WW domain binding protein 2
chr2_+_44275491 0.42 ENST00000410056.7
ENST00000409741.5
ENST00000409229.7
solute carrier family 3 member 1
chr12_-_110689751 0.42 ENST00000439744.6
ENST00000549442.5
hydrogen voltage gated channel 1
chr1_+_240091866 0.41 ENST00000319653.14
formin 2
chr17_-_17281232 0.41 ENST00000417352.5
ENST00000268717.10
COP9 signalosome subunit 3
chr19_+_4402685 0.41 ENST00000585854.1
chromatin assembly factor 1 subunit A
chr13_-_46142834 0.40 ENST00000674665.1
lymphocyte cytosolic protein 1
chr14_+_22096017 0.40 ENST00000390452.2
T cell receptor delta variable 1
chrX_+_86714623 0.40 ENST00000484479.1
dachshund family transcription factor 2
chrX_-_154805386 0.40 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
membrane palmitoylated protein 1
chr9_+_33240159 0.40 ENST00000379721.4
serine peptidase inhibitor Kazal type 4
chr17_-_45425620 0.39 ENST00000376922.6
Rho GTPase activating protein 27
chr14_+_21768482 0.39 ENST00000390428.3
T cell receptor alpha variable 6
chr12_+_64824602 0.39 ENST00000539867.6
ENST00000544457.1
ENST00000539120.1
TBC1 domain family member 30
chr1_+_99850348 0.39 ENST00000361915.8
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr1_+_247605586 0.39 ENST00000320002.3
olfactory receptor family 2 subfamily G member 3
chr4_+_37960397 0.39 ENST00000504686.2
pituitary tumor-transforming 2
chr13_-_83882390 0.39 ENST00000377084.3
SLIT and NTRK like family member 1
chr13_+_46212002 0.39 ENST00000676446.1
leucine rich repeat containing 63
chr19_-_50639282 0.39 ENST00000598997.1
synaptotagmin 3
chr11_+_73648979 0.38 ENST00000540431.1
pleckstrin homology domain containing B1
chr6_+_42915989 0.38 ENST00000441198.4
ENST00000446507.5
ENST00000616441.2
pre T cell antigen receptor alpha
chr1_-_156859087 0.38 ENST00000368195.4
insulin receptor related receptor
chr18_+_35041387 0.38 ENST00000538170.6
ENST00000300249.10
ENST00000588910.5
microtubule associated protein RP/EB family member 2
chr7_-_93574721 0.38 ENST00000426151.7
ENST00000649521.1
calcitonin receptor
chr3_-_121660892 0.37 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr16_-_68000549 0.37 ENST00000575510.5
dipeptidase 2
chr8_-_101206064 0.37 ENST00000518336.5
ENST00000520454.1
zinc finger protein 706
chr3_+_160677152 0.37 ENST00000320767.4
ADP ribosylation factor like GTPase 14
chr19_-_51501755 0.37 ENST00000291707.8
sialic acid binding Ig like lectin 12
chr1_-_150765735 0.37 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr3_+_124384513 0.36 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
kalirin RhoGEF kinase
chr5_-_74640649 0.36 ENST00000537006.1
ectodermal-neural cortex 1
chr9_-_71911183 0.35 ENST00000333421.7
abhydrolase domain containing 17B, depalmitoylase
chr2_+_240605417 0.35 ENST00000319838.10
ENST00000403859.1
G protein-coupled receptor 35
chr1_+_54806063 0.35 ENST00000358193.7
ENST00000371273.4
lymphocyte expansion molecule
chr12_-_55927756 0.35 ENST00000549939.1
PYM homolog 1, exon junction complex associated factor
chr5_-_59356962 0.35 ENST00000405755.6
phosphodiesterase 4D
chr9_-_127735286 0.34 ENST00000336067.10
ENST00000373284.10
ENST00000373281.8
ENST00000463577.2
torsin family 2 member A
chr5_+_31532277 0.34 ENST00000507818.6
ENST00000325366.14
chromosome 5 open reading frame 22
chr9_+_135702172 0.34 ENST00000487664.5
ENST00000371757.7
ENST00000628528.2
potassium sodium-activated channel subfamily T member 1
chr12_-_70754631 0.34 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr6_+_25652272 0.34 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr16_-_15643024 0.34 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr15_+_62066975 0.33 ENST00000355522.5
C2 calcium dependent domain containing 4A
chr12_+_110502307 0.33 ENST00000409778.7
ENST00000409300.6
RAD9 checkpoint clamp component B
chr9_+_135095978 0.33 ENST00000545657.1
olfactomedin 1
chr8_+_85987287 0.33 ENST00000521564.1
ATPase H+ transporting V0 subunit d2
chr12_+_69239627 0.33 ENST00000551516.1
cleavage and polyadenylation specific factor 6
chrM_+_8489 0.33 ENST00000361899.2
mitochondrially encoded ATP synthase membrane subunit 6
chr22_+_44026283 0.32 ENST00000619710.4
parvin beta
chr15_+_76995374 0.32 ENST00000559161.5
proline-serine-threonine phosphatase interacting protein 1
chr18_-_5396265 0.32 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr9_-_21351378 0.31 ENST00000380210.1
interferon alpha 6
chr2_-_36966503 0.31 ENST00000263918.9
striatin
chr16_+_20451532 0.31 ENST00000576361.5
acyl-CoA synthetase medium chain family member 2A
chr2_-_106160106 0.30 ENST00000479774.5
UDP-glucuronate decarboxylase 1
chr2_+_100974849 0.30 ENST00000450763.1
neuronal PAS domain protein 2
chr7_+_6009222 0.30 ENST00000400479.6
ENST00000223029.8
ENST00000395236.2
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
chr11_-_31804067 0.30 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
paired box 6
chr19_+_54630497 0.30 ENST00000396332.8
ENST00000427581.6
leukocyte immunoglobulin like receptor B1
chr15_-_80252205 0.30 ENST00000560778.3
cortexin domain containing 1
chr1_-_72100930 0.30 ENST00000306821.3
neuronal growth regulator 1
chr12_-_7751605 0.29 ENST00000354629.9
C-type lectin domain family 4 member C
chr6_-_111793900 0.29 ENST00000462598.7
FYN proto-oncogene, Src family tyrosine kinase
chr11_+_65181920 0.29 ENST00000279247.11
ENST00000532285.1
ENST00000534373.5
calpain 1
chr1_+_99850485 0.29 ENST00000370165.7
ENST00000370163.7
ENST00000294724.8
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr5_-_79512794 0.29 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr1_-_209784521 0.29 ENST00000294811.2
chromosome 1 open reading frame 74
chr5_+_149581368 0.28 ENST00000333677.7
Rho guanine nucleotide exchange factor 37
chr5_-_56116946 0.28 ENST00000434982.2
ankyrin repeat domain 55
chr16_-_90019414 0.28 ENST00000002501.11
dysbindin domain containing 1
chr12_-_69699331 0.27 ENST00000548658.1
ENST00000476098.5
bestrophin 3
chr13_-_52450590 0.27 ENST00000378060.9
vacuolar protein sorting 36 homolog
chr12_-_69699382 0.27 ENST00000551160.5
bestrophin 3
chr12_+_69239592 0.27 ENST00000456847.7
ENST00000266679.8
cleavage and polyadenylation specific factor 6
chr3_-_112974912 0.27 ENST00000440122.6
ENST00000490004.1
CD200 receptor 1
chr2_+_44275473 0.27 ENST00000260649.11
solute carrier family 3 member 1
chr12_-_69699353 0.27 ENST00000331471.8
bestrophin 3
chr20_+_841238 0.27 ENST00000541082.2
family with sequence similarity 110 member A
chr17_-_30334050 0.27 ENST00000328886.5
ENST00000538566.6
transmembrane and immunoglobulin domain containing 1
chr11_-_59713845 0.26 ENST00000307552.3
olfactory receptor family 10 subfamily V member 1
chr4_-_122456725 0.26 ENST00000226730.5
interleukin 2
chr6_+_42916046 0.26 ENST00000304672.6
pre T cell antigen receptor alpha
chr22_+_37282464 0.26 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
cytohesin 4
chrX_-_111412162 0.26 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr22_-_38084093 0.26 ENST00000681075.1
solute carrier family 16 member 8
chr3_+_124384376 0.25 ENST00000682636.1
kalirin RhoGEF kinase
chr19_+_7049321 0.25 ENST00000381393.3
methyl-CpG binding domain protein 3 like 2
chrX_+_3066833 0.24 ENST00000359361.2
arylsulfatase F
chr19_-_41688258 0.24 ENST00000401731.6
ENST00000006724.7
CEA cell adhesion molecule 7
chr7_+_157336988 0.23 ENST00000262177.9
ENST00000417758.5
ENST00000443280.5
DnaJ heat shock protein family (Hsp40) member B6
chr12_-_69699285 0.23 ENST00000553096.5
ENST00000330891.10
bestrophin 3
chr11_+_65182413 0.23 ENST00000531068.5
ENST00000527699.5
ENST00000533909.5
ENST00000527323.5
calpain 1
chr12_-_11092313 0.23 ENST00000531678.1
taste 2 receptor member 43
chrX_-_47145035 0.22 ENST00000276062.8
NADH:ubiquinone oxidoreductase subunit B11
chr13_+_111115303 0.22 ENST00000646102.2
ENST00000449979.5
Rho guanine nucleotide exchange factor 7
chr11_+_5689691 0.22 ENST00000425490.5
tripartite motif containing 22
chr15_-_68205319 0.22 ENST00000467889.3
ENST00000448060.7
calmodulin like 4
chr11_+_74988896 0.22 ENST00000526068.1
ENST00000294064.9
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
neuraminidase 3
chr8_+_24294044 0.22 ENST00000265769.9
ADAM metallopeptidase domain 28
chr15_-_55249029 0.22 ENST00000566877.5
RAB27A, member RAS oncogene family
chr1_-_11858935 0.22 ENST00000376468.4
natriuretic peptide B
chr2_-_240821363 0.22 ENST00000675940.1
kinesin family member 1A
chr14_+_21749163 0.22 ENST00000390427.3
T cell receptor alpha variable 5
chr1_-_155911365 0.22 ENST00000651833.1
ENST00000539040.5
ENST00000651853.1
Ras like without CAAX 1
chr6_-_26234978 0.22 ENST00000244534.7
H1.3 linker histone, cluster member
chr7_-_33040893 0.21 ENST00000643244.1
ENST00000409467.6
ENST00000449201.5
5'-nucleotidase, cytosolic IIIA
chr13_+_31739542 0.21 ENST00000380314.2
relaxin family peptide receptor 2
chr19_+_8052752 0.21 ENST00000315626.6
ENST00000253451.9
C-C motif chemokine ligand 25
chr4_+_153466324 0.21 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr16_+_24539536 0.21 ENST00000568015.5
ENST00000319715.10
RB binding protein 6, ubiquitin ligase
chr1_-_248645278 0.21 ENST00000641268.1
olfactory receptor family 2 subfamily T member 35
chr19_-_45602153 0.21 ENST00000544371.1
ENST00000323040.5
outer mitochondrial membrane lipid metabolism regulator OPA3
G protein-coupled receptor 4
chr3_-_47891269 0.21 ENST00000335271.9
microtubule associated protein 4
chr16_-_90019821 0.20 ENST00000568838.2
dysbindin domain containing 1
chr12_-_8066331 0.20 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr6_+_155013646 0.20 ENST00000538270.5
ENST00000535231.5
TIAM Rac1 associated GEF 2
chr17_+_58238694 0.20 ENST00000581008.1
lactoperoxidase
chr2_+_74654304 0.20 ENST00000453930.5
ssemaphorin 4F
chrX_-_47144680 0.19 ENST00000377811.4
NADH:ubiquinone oxidoreductase subunit B11
chr8_+_24294107 0.19 ENST00000437154.6
ADAM metallopeptidase domain 28
chr12_-_110502065 0.19 ENST00000447578.6
ENST00000546588.1
ENST00000360579.11
ENST00000549578.6
ENST00000549970.5
VPS29 retromer complex component

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.5 2.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3 0.8 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.2 0.9 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 0.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 1.7 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.1 1.2 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.4 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.3 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.1 0.7 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.4 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 2.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.5 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 1.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.3 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.1 0.5 GO:0070269 pyroptosis(GO:0070269)
0.1 0.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.5 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 1.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.6 GO:0008050 female courtship behavior(GO:0008050)
0.1 1.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.4 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.7 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.2 GO:0072143 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.3 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.3 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 1.0 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.5 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.5 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 2.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.4 GO:0045651 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of macrophage differentiation(GO:0045651)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.8 GO:0042311 vasodilation(GO:0042311)
0.0 0.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.6 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860) coenzyme transport(GO:0051182)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.0 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.5 GO:0097169 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 2.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.6 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.9 GO:0097386 glial cell projection(GO:0097386)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 0.9 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 0.9 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 1.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 1.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.3 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.1 1.5 GO:0070492 peptidoglycan binding(GO:0042834) oligosaccharide binding(GO:0070492)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 2.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 2.9 GO:0005496 steroid binding(GO:0005496)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 3.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway