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Illumina Body Map 2 (GSE30611)

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Results for SOX30

Z-value: 1.05

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Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
SOX30
ENSG00000039600.11 SRY-box transcription factor 30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg38_v1_chr5_-_157652364_1576523850.038.8e-01Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_127900958 3.59 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
THEMIS
thymocyte selection associated
chr11_-_35419542 3.36 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
SLC1A2
solute carrier family 1 member 2
chr4_-_175812746 3.34 ENST00000393658.6
GPM6A
glycoprotein M6A
chr2_-_157325808 3.31 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ERMN
ermin
chr11_-_35420050 2.79 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
SLC1A2
solute carrier family 1 member 2
chr8_+_79611036 2.78 ENST00000220876.12
ENST00000518111.5
STMN2
stathmin 2
chr5_-_147081428 2.70 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr11_-_35419213 2.62 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
SLC1A2
solute carrier family 1 member 2
chr12_-_98894830 2.61 ENST00000549797.5
ENST00000333732.11
ENST00000341752.11
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr3_+_181711915 2.53 ENST00000325404.3
SOX2
SRY-box transcription factor 2
chr11_-_35419462 2.34 ENST00000643522.1
SLC1A2
solute carrier family 1 member 2
chr5_-_147081462 2.34 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr11_-_35420017 2.26 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
SLC1A2
solute carrier family 1 member 2
chr12_-_11395556 2.20 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
PRB2
PRB1
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr1_-_25905470 2.12 ENST00000446334.1
STMN1
stathmin 1
chr11_-_35419899 2.06 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
SLC1A2
solute carrier family 1 member 2
chr12_-_11310420 1.95 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
PRB4
proline rich protein BstNI subfamily 4
chr17_-_40665121 1.89 ENST00000394052.5
KRT222
keratin 222
chr2_-_240820945 1.88 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
KIF1A
kinesin family member 1A
chr11_-_85719313 1.87 ENST00000526999.5
SYTL2
synaptotagmin like 2
chr9_-_131270493 1.82 ENST00000372269.7
ENST00000464831.1
FAM78A
family with sequence similarity 78 member A
chr15_+_92883413 1.82 ENST00000629685.2
ENSG00000279765.3
novel protein
chr21_+_29300111 1.78 ENST00000451655.5
BACH1
BTB domain and CNC homolog 1
chr12_-_49187369 1.77 ENST00000547939.6
TUBA1A
tubulin alpha 1a
chrX_-_24672654 1.76 ENST00000379145.5
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr8_-_81112055 1.70 ENST00000220597.4
PAG1
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr7_+_142352802 1.62 ENST00000634605.1
TRBV7-2
T cell receptor beta variable 7-2
chr1_-_25905098 1.59 ENST00000374291.5
STMN1
stathmin 1
chr12_+_10929229 1.55 ENST00000381847.7
ENST00000396400.4
PRH2
proline rich protein HaeIII subfamily 2
chr12_-_10130241 1.52 ENST00000353231.9
ENST00000525605.1
CLEC7A
C-type lectin domain containing 7A
chr12_-_98895263 1.51 ENST00000548447.1
ENST00000546364.7
ENST00000552748.5
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr17_-_75153826 1.46 ENST00000481647.5
ENST00000470924.5
JPT1
Jupiter microtubule associated homolog 1
chrX_-_143636094 1.45 ENST00000356928.2
SLITRK4
SLIT and NTRK like family member 4
chr1_+_154429315 1.43 ENST00000476006.5
IL6R
interleukin 6 receptor
chr12_+_50504970 1.42 ENST00000301180.10
DIP2B
disco interacting protein 2 homolog B
chr21_+_29299368 1.40 ENST00000399921.5
BACH1
BTB domain and CNC homolog 1
chr1_-_243255320 1.38 ENST00000366544.5
ENST00000366543.5
CEP170
centrosomal protein 170
chr12_-_98895199 1.35 ENST00000552407.5
ENST00000551613.5
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr22_+_50170720 1.34 ENST00000159647.9
ENST00000395842.3
PANX2
pannexin 2
chrX_-_15854743 1.29 ENST00000450644.2
AP1S2
adaptor related protein complex 1 subunit sigma 2
chrX_-_15854791 1.26 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
AP1S2
adaptor related protein complex 1 subunit sigma 2
chr1_-_243255170 1.22 ENST00000366542.6
CEP170
centrosomal protein 170
chr8_+_42338454 1.19 ENST00000532157.5
ENST00000520008.5
POLB
DNA polymerase beta
chr12_-_11269696 1.18 ENST00000381842.7
PRB3
proline rich protein BstNI subfamily 3
chr12_-_11269805 1.16 ENST00000538488.2
PRB3
proline rich protein BstNI subfamily 3
chr10_-_60300474 1.15 ENST00000503925.1
ANK3
ankyrin 3
chr3_+_147393718 1.15 ENST00000488404.5
ZIC1
Zic family member 1
chr11_-_85719045 1.13 ENST00000533057.6
ENST00000533892.5
SYTL2
synaptotagmin like 2
chr12_-_10130143 1.13 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
CLEC7A
C-type lectin domain containing 7A
chr7_-_14903319 1.10 ENST00000403951.6
DGKB
diacylglycerol kinase beta
chr7_+_142670734 1.10 ENST00000390398.3
TRBV25-1
T cell receptor beta variable 25-1
chr9_+_100473140 1.02 ENST00000374879.5
TMEFF1
transmembrane protein with EGF like and two follistatin like domains 1
chr1_+_240091866 1.02 ENST00000319653.14
FMN2
formin 2
chr11_-_85719160 1.01 ENST00000389958.7
ENST00000527794.5
SYTL2
synaptotagmin like 2
chr11_-_85719111 1.01 ENST00000529581.5
ENST00000533577.1
SYTL2
synaptotagmin like 2
chr17_+_69502154 0.94 ENST00000589295.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_-_18424533 0.90 ENST00000417717.6
SATB1
SATB homeobox 1
chr15_-_48963912 0.89 ENST00000332408.9
SHC4
SHC adaptor protein 4
chr17_+_69502397 0.86 ENST00000613873.4
ENST00000589647.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_-_165203870 0.86 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr3_-_13042419 0.86 ENST00000647458.1
IQSEC1
IQ motif and Sec7 domain ArfGEF 1
chr11_+_36296281 0.84 ENST00000530639.6
PRR5L
proline rich 5 like
chr1_-_204494701 0.83 ENST00000429009.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr11_+_128693887 0.82 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr8_+_42338477 0.81 ENST00000518925.5
ENST00000265421.9
POLB
DNA polymerase beta
chr11_+_128694052 0.79 ENST00000527786.7
ENST00000534087.3
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_-_83673544 0.77 ENST00000503117.1
ENST00000510978.5
HAPLN1
hyaluronan and proteoglycan link protein 1
chr12_-_10130082 0.76 ENST00000533022.5
CLEC7A
C-type lectin domain containing 7A
chr4_+_143381939 0.72 ENST00000505913.5
GAB1
GRB2 associated binding protein 1
chr17_+_69502255 0.71 ENST00000588110.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_+_74235377 0.66 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr1_-_243255348 0.65 ENST00000522995.1
CEP170
centrosomal protein 170
chr2_-_165204042 0.64 ENST00000283254.12
ENST00000453007.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr10_-_27981805 0.64 ENST00000673512.1
ENST00000672877.1
ENST00000480504.1
ODAD2
outer dynein arm docking complex subunit 2
chr5_+_68292486 0.64 ENST00000519025.5
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr2_-_37672178 0.64 ENST00000457889.1
CDC42EP3
CDC42 effector protein 3
chr2_+_178320228 0.63 ENST00000315022.2
OSBPL6
oxysterol binding protein like 6
chr7_-_83162899 0.61 ENST00000423517.6
PCLO
piccolo presynaptic cytomatrix protein
chr6_+_125919296 0.59 ENST00000444128.2
NCOA7
nuclear receptor coactivator 7
chr5_-_160852200 0.58 ENST00000327245.10
ATP10B
ATPase phospholipid transporting 10B (putative)
chr5_-_135399211 0.53 ENST00000312469.8
ENST00000423969.6
MACROH2A1
macroH2A.1 histone
chr11_-_102452758 0.53 ENST00000398136.7
ENST00000361236.7
TMEM123
transmembrane protein 123
chr15_+_76336755 0.51 ENST00000290759.9
ISL2
ISL LIM homeobox 2
chr3_+_141262614 0.51 ENST00000504264.5
PXYLP1
2-phosphoxylose phosphatase 1
chr2_-_240821363 0.49 ENST00000675940.1
KIF1A
kinesin family member 1A
chr2_-_37671633 0.49 ENST00000295324.4
CDC42EP3
CDC42 effector protein 3
chr6_+_125919210 0.49 ENST00000438495.6
NCOA7
nuclear receptor coactivator 7
chr2_+_86441995 0.48 ENST00000427678.1
KDM3A
lysine demethylase 3A
chr2_-_37672448 0.47 ENST00000611976.1
CDC42EP3
CDC42 effector protein 3
chr20_-_63979629 0.43 ENST00000369886.8
ENST00000450107.1
SAMD10
sterile alpha motif domain containing 10
chr6_-_11778781 0.42 ENST00000414691.8
ENST00000229583.9
ADTRP
androgen dependent TFPI regulating protein
chr8_+_24294044 0.42 ENST00000265769.9
ADAM28
ADAM metallopeptidase domain 28
chr20_+_38962299 0.38 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DHX35
ENSG00000277581.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr9_-_71768386 0.36 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chr16_+_4495852 0.36 ENST00000575129.5
ENST00000398595.7
ENST00000414777.5
HMOX2
heme oxygenase 2
chr16_+_68539213 0.33 ENST00000570495.5
ENST00000564323.5
ENST00000562156.5
ENST00000573685.5
ENST00000563169.7
ENST00000611381.4
ZFP90
ZFP90 zinc finger protein
chr10_-_59363176 0.32 ENST00000512919.5
FAM13C
family with sequence similarity 13 member C
chr17_-_64390592 0.31 ENST00000563523.5
PECAM1
platelet and endothelial cell adhesion molecule 1
chr12_+_92702843 0.28 ENST00000397833.3
PLEKHG7
pleckstrin homology and RhoGEF domain containing G7
chr8_+_24294107 0.26 ENST00000437154.6
ADAM28
ADAM metallopeptidase domain 28
chr13_-_85799400 0.25 ENST00000647374.2
SLITRK6
SLIT and NTRK like family member 6
chr12_+_27470632 0.22 ENST00000535986.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr10_-_122699768 0.22 ENST00000432000.5
C10orf120
chromosome 10 open reading frame 120
chr5_-_135399863 0.21 ENST00000510038.1
ENST00000304332.8
MACROH2A1
macroH2A.1 histone
chr11_+_63369779 0.21 ENST00000279178.4
SLC22A9
solute carrier family 22 member 9
chr16_-_2787550 0.19 ENST00000682474.1
PRSS33
serine protease 33
chr12_+_92702983 0.19 ENST00000344636.6
ENST00000544406.2
PLEKHG7
pleckstrin homology and RhoGEF domain containing G7
chr11_+_196761 0.18 ENST00000325113.9
ODF3
outer dense fiber of sperm tails 3
chr15_+_56918763 0.18 ENST00000557843.5
TCF12
transcription factor 12
chr11_+_65890627 0.17 ENST00000312579.4
CCDC85B
coiled-coil domain containing 85B
chr15_+_56919120 0.17 ENST00000557947.5
TCF12
transcription factor 12
chr17_+_7420315 0.16 ENST00000323675.4
SPEM1
spermatid maturation 1
chr10_-_122699836 0.15 ENST00000329446.5
C10orf120
chromosome 10 open reading frame 120
chr12_-_95217373 0.14 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FGD6
FYVE, RhoGEF and PH domain containing 6
chr6_+_12290353 0.14 ENST00000379375.6
EDN1
endothelin 1
chr3_-_149221811 0.14 ENST00000455472.3
ENST00000264613.11
CP
ceruloplasmin
chr1_+_40477248 0.13 ENST00000372706.6
ZFP69
ZFP69 zinc finger protein
chr1_+_192316992 0.13 ENST00000417209.2
RGS21
regulator of G protein signaling 21
chr13_-_41019289 0.11 ENST00000239882.7
ELF1
E74 like ETS transcription factor 1
chrX_+_80420466 0.10 ENST00000308293.5
TENT5D
terminal nucleotidyltransferase 5D
chr6_-_89217339 0.10 ENST00000454853.7
GABRR1
gamma-aminobutyric acid type A receptor subunit rho1
chr8_+_7836433 0.09 ENST00000314265.3
DEFB104A
defensin beta 104A
chr10_-_114632011 0.09 ENST00000651023.1
ABLIM1
actin binding LIM protein 1
chr1_-_167914089 0.08 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
ADCY10
adenylate cyclase 10
chrX_+_44844015 0.08 ENST00000339042.6
DUSP21
dual specificity phosphatase 21
chrX_+_102937272 0.07 ENST00000218249.7
RAB40AL
RAB40A like
chr3_+_19947074 0.07 ENST00000273047.9
RAB5A
RAB5A, member RAS oncogene family
chr1_+_65419 0.07 ENST00000641515.2
OR4F5
olfactory receptor family 4 subfamily F member 5
chr19_+_107104 0.04 ENST00000585993.3
ENST00000618231.3
OR4F17
olfactory receptor family 4 subfamily F member 17
chr2_+_29113989 0.03 ENST00000404424.5
CLIP4
CAP-Gly domain containing linker protein family member 4
chr12_+_55492378 0.03 ENST00000548615.1
OR6C68
olfactory receptor family 6 subfamily C member 68
chr17_-_676348 0.02 ENST00000681510.1
ENST00000679680.1
VPS53
VPS53 subunit of GARP complex
chr14_+_35826298 0.01 ENST00000216807.12
BRMS1L
BRMS1 like transcriptional repressor
chr3_-_71306012 0.01 ENST00000649431.1
ENST00000610810.5
FOXP1
forkhead box P1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 15.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.7 2.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.7 5.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.5 3.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.5 2.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 2.0 GO:0006288 base-excision repair, base-free sugar-phosphate removal(GO:0006286) base-excision repair, DNA ligation(GO:0006288)
0.3 5.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.3 1.4 GO:0002384 hepatic immune response(GO:0002384)
0.3 3.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 2.5 GO:0001714 endodermal cell fate specification(GO:0001714)
0.2 1.0 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.2 0.6 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 5.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 1.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 3.6 GO:0043383 negative T cell selection(GO:0043383)
0.1 3.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 1.3 GO:0034214 protein hexamerization(GO:0034214)
0.1 1.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 1.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.0 3.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 2.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 1.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 2.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0060584 nitric oxide transport(GO:0030185) rhythmic synaptic transmission(GO:0060024) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.5 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.7 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 1.1 GO:0007628 adult walking behavior(GO:0007628)
0.0 1.5 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.6 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0072011 glomerular endothelium development(GO:0072011)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 1.7 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 1.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 GO:0033269 internode region of axon(GO:0033269)
0.2 1.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 15.4 GO:0030673 axolemma(GO:0030673)
0.2 0.6 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.1 4.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 5.5 GO:0015030 Cajal body(GO:0015030)
0.1 1.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 3.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.3 GO:0005921 gap junction(GO:0005921)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 3.2 GO:0005814 centriole(GO:0005814)
0.0 4.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 2.8 GO:0030426 growth cone(GO:0030426)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 15.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 1.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.4 1.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.4 1.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 5.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 3.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 5.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 3.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 2.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.0 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.5 GO:0035198 miRNA binding(GO:0035198)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 2.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 5.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.0 PID ATR PATHWAY ATR signaling pathway
0.1 1.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.1 PID SHP2 PATHWAY SHP2 signaling
0.0 1.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 15.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins