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Illumina Body Map 2 (GSE30611)

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Results for SOX6

Z-value: 1.36

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
ENSG00000110693.19 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg38_v1_chr11_-_16356538_16356551-0.402.4e-02Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106235582 4.05 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr14_-_106335613 3.89 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr17_-_64390852 3.49 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr12_+_53097656 3.43 ENST00000301464.4
insulin like growth factor binding protein 6
chr1_-_201507116 3.34 ENST00000340006.7
ENST00000526256.5
ENST00000526723.5
ENST00000524951.5
cysteine and glycine rich protein 1
chr6_-_106974721 3.26 ENST00000606017.2
ENST00000620405.1
CD24 molecule
chr13_-_110307131 3.20 ENST00000543140.6
ENST00000375820.10
collagen type IV alpha 1 chain
chr5_-_168883333 3.06 ENST00000404867.7
slit guidance ligand 3
chr17_-_64390592 3.06 ENST00000563523.5
platelet and endothelial cell adhesion molecule 1
chr5_+_40909490 3.02 ENST00000313164.10
complement C7
chr14_+_22836574 2.90 ENST00000548162.2
ENST00000311852.11
matrix metallopeptidase 14
chr22_-_19524400 2.89 ENST00000618236.2
claudin 5
chr7_+_134779663 2.82 ENST00000361901.6
caldesmon 1
chr1_-_25906931 2.79 ENST00000357865.6
stathmin 1
chr7_+_134779625 2.79 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr14_-_106117159 2.77 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr2_-_1744442 2.71 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr15_-_65067938 2.70 ENST00000421977.7
ENST00000220062.9
RAS like family 12
chr1_+_19644284 2.70 ENST00000375136.8
NBL1, DAN family BMP antagonist
chr14_-_106211453 2.66 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr6_+_113857333 2.62 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chrX_-_45200828 2.57 ENST00000398000.7
divergent protein kinase domain 2B
chrX_+_66164340 2.55 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr9_+_98943705 2.54 ENST00000610452.1
collagen type XV alpha 1 chain
chr2_+_69013170 2.47 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr4_-_137532452 2.44 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr1_-_25906457 2.43 ENST00000426559.6
stathmin 1
chrX_+_66164210 2.43 ENST00000343002.7
ENST00000336279.9
hephaestin
chr5_+_147878703 2.40 ENST00000296694.5
secretoglobin family 3A member 2
chr3_-_123620496 2.40 ENST00000578202.1
myosin light chain kinase
chr12_+_6226136 2.36 ENST00000676764.1
ENST00000646407.1
CD9 molecule
chr6_-_75206044 2.30 ENST00000322507.13
collagen type XII alpha 1 chain
chr14_-_106470788 2.29 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr9_-_73865 2.25 ENST00000642633.1
WASH complex subunit 1
chr3_-_123620571 2.21 ENST00000583087.5
myosin light chain kinase
chr9_+_68356603 2.08 ENST00000396396.6
phosphoglucomutase 5
chr8_+_24294044 2.07 ENST00000265769.9
ADAM metallopeptidase domain 28
chr1_-_25906411 2.06 ENST00000455785.7
stathmin 1
chr12_-_8662808 2.04 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chrX_-_45200895 2.04 ENST00000377934.4
divergent protein kinase domain 2B
chr1_+_15758768 2.01 ENST00000483633.6
ENST00000502739.5
ENST00000375766.8
ENST00000431771.6
filamin binding LIM protein 1
chr13_+_110305806 2.00 ENST00000400163.7
collagen type IV alpha 2 chain
chr8_-_33567118 2.00 ENST00000256257.2
ring finger protein 122
chr16_+_23755015 1.99 ENST00000300113.3
calcineurin like EF-hand protein 2
chr11_+_36296281 1.99 ENST00000530639.6
proline rich 5 like
chr9_+_136980211 1.98 ENST00000444903.2
prostaglandin D2 synthase
chr19_-_42442938 1.97 ENST00000601181.6
C-X-C motif chemokine ligand 17
chr3_+_181711915 1.96 ENST00000325404.3
SRY-box transcription factor 2
chr5_-_180591488 1.94 ENST00000292641.4
secretoglobin family 3A member 1
chr13_+_110307276 1.93 ENST00000360467.7
ENST00000650540.1
collagen type IV alpha 2 chain
chr6_+_31815532 1.92 ENST00000375651.7
ENST00000608703.1
heat shock protein family A (Hsp70) member 1A
chr2_+_231708511 1.85 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
prothymosin alpha
chr2_-_37672178 1.82 ENST00000457889.1
CDC42 effector protein 3
chr12_+_56041893 1.81 ENST00000552361.1
ENST00000646449.2
ribosomal protein S26
chr12_+_10929229 1.81 ENST00000381847.7
ENST00000396400.4
proline rich protein HaeIII subfamily 2
chr12_-_11310420 1.78 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr2_-_37671633 1.78 ENST00000295324.4
CDC42 effector protein 3
chr1_-_94927079 1.77 ENST00000370206.9
ENST00000394202.8
calponin 3
chr11_+_73950985 1.76 ENST00000339764.6
DnaJ heat shock protein family (Hsp40) member B13
chr8_-_119673368 1.75 ENST00000427067.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_+_228149922 1.70 ENST00000366714.3
gap junction protein gamma 2
chrX_-_154371210 1.66 ENST00000369856.8
ENST00000422373.6
ENST00000360319.9
filamin A
chr7_-_108003122 1.66 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr14_-_106389858 1.65 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr9_-_137302264 1.65 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr12_-_88580459 1.65 ENST00000552044.1
ENST00000644744.1
ENST00000357116.4
KIT ligand
chr2_+_205682491 1.63 ENST00000360409.7
ENST00000450507.5
ENST00000357785.10
ENST00000417189.5
neuropilin 2
chr4_-_7939789 1.60 ENST00000420658.6
ENST00000358461.6
actin filament associated protein 1
chr9_+_110090197 1.60 ENST00000480388.1
PALM2 and AKAP2 fusion
chr2_-_216695540 1.60 ENST00000233813.5
insulin like growth factor binding protein 5
chr2_+_69013414 1.58 ENST00000681816.1
ENST00000482235.2
ANTXR cell adhesion molecule 1
chr7_+_80638510 1.56 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr12_-_47819866 1.55 ENST00000354334.7
ENST00000430670.5
ENST00000552960.5
ENST00000440293.5
ENST00000080059.12
histone deacetylase 7
chr8_+_24294107 1.52 ENST00000437154.6
ADAM metallopeptidase domain 28
chr1_-_25905989 1.47 ENST00000399728.5
stathmin 1
chr14_-_91417805 1.46 ENST00000389857.11
ENST00000553403.1
coiled-coil domain containing 88C
chr8_+_79611036 1.42 ENST00000220876.12
ENST00000518111.5
stathmin 2
chr13_-_41019289 1.42 ENST00000239882.7
E74 like ETS transcription factor 1
chr4_-_102345196 1.41 ENST00000683412.1
ENST00000682227.1
solute carrier family 39 member 8
chr7_+_150379316 1.41 ENST00000483664.5
ENST00000329630.10
novel transcript
zinc finger protein 775
chr3_-_120450981 1.40 ENST00000424703.6
ENST00000469005.1
ENST00000295633.8
follistatin like 1
chr7_+_80638633 1.38 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr12_-_8662619 1.37 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr5_+_141223332 1.37 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr11_-_44950151 1.37 ENST00000533940.5
ENST00000533937.1
tumor protein p53 inducible protein 11
chr2_+_69013379 1.34 ENST00000409349.7
ANTXR cell adhesion molecule 1
chrX_+_12975216 1.32 ENST00000380635.5
thymosin beta 4 X-linked
chr4_-_102345061 1.30 ENST00000394833.6
solute carrier family 39 member 8
chr19_-_1568301 1.30 ENST00000402693.5
mex-3 RNA binding family member D
chr11_+_46381033 1.29 ENST00000359803.7
midkine
chr8_-_6563238 1.29 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr19_+_5681140 1.27 ENST00000579559.1
ENST00000577222.5
hydroxysteroid 11-beta dehydrogenase 1 like
ribosomal protein L36
chr6_-_106975452 1.26 ENST00000619869.1
ENST00000619133.4
CD24 molecule
chr6_-_49744378 1.26 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr20_+_6767678 1.26 ENST00000378827.5
bone morphogenetic protein 2
chr2_+_54456311 1.26 ENST00000615901.4
ENST00000356805.9
spectrin beta, non-erythrocytic 1
chr7_+_80638662 1.23 ENST00000394788.7
CD36 molecule
chr12_+_92702983 1.19 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr9_+_130172343 1.18 ENST00000372398.6
neuronal calcium sensor 1
chr18_-_55321640 1.17 ENST00000637169.2
transcription factor 4
chr8_-_6563409 1.16 ENST00000325203.9
angiopoietin 2
chr11_+_128694052 1.16 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr22_+_37563640 1.15 ENST00000415670.1
CDC42 effector protein 1
chr4_+_54657918 1.15 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr11_-_8870917 1.13 ENST00000527347.5
ENST00000526241.5
ENST00000526126.5
ENST00000530938.5
ENST00000526057.5
DENN domain containing 2B
chr1_+_86424154 1.12 ENST00000370565.5
chloride channel accessory 2
chr22_-_38317423 1.11 ENST00000396832.6
ENST00000403904.5
ENST00000405675.7
casein kinase 1 epsilon
chr11_-_85719160 1.11 ENST00000389958.7
ENST00000527794.5
synaptotagmin like 2
chr3_-_57165332 1.10 ENST00000296318.12
interleukin 17 receptor D
chr17_-_40885232 1.09 ENST00000167588.4
keratin 20
chr11_-_85719045 1.09 ENST00000533057.6
ENST00000533892.5
synaptotagmin like 2
chr4_+_53377749 1.08 ENST00000507166.5
novel FIP1L1-PDGFRA fusion protein
chr13_+_23570370 1.07 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr1_+_13585453 1.07 ENST00000487038.5
ENST00000475043.5
podoplanin
chr21_-_14658812 1.06 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr11_+_60924452 1.06 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
transmembrane protein 132A
chr5_-_147454240 1.06 ENST00000512722.1
dihydropyrimidinase like 3
chr11_+_128693887 1.05 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr19_-_19628197 1.05 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr12_+_63844758 1.05 ENST00000631006.2
SLIT-ROBO Rho GTPase activating protein 1
chr11_-_44950839 1.04 ENST00000395648.7
ENST00000531928.6
tumor protein p53 inducible protein 11
chr11_-_85719111 1.00 ENST00000529581.5
ENST00000533577.1
synaptotagmin like 2
chr18_+_6729698 0.99 ENST00000383472.9
Rho GTPase activating protein 28
chr15_+_92883413 0.98 ENST00000629685.2
novel protein
chr15_-_40874216 0.97 ENST00000220507.5
ras homolog family member V
chr2_-_70248454 0.96 ENST00000416149.6
ENST00000282574.8
TIA1 cytotoxic granule associated RNA binding protein
chr7_+_120988683 0.95 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr8_-_6563044 0.94 ENST00000338312.10
angiopoietin 2
chr16_+_89923333 0.94 ENST00000315491.12
ENST00000555576.5
ENST00000554336.5
ENST00000553967.1
tubulin beta 3 class III
chr5_-_157575767 0.94 ENST00000257527.9
ADAM metallopeptidase domain 19
chr12_-_52926459 0.94 ENST00000552150.5
keratin 8
chr15_+_51751587 0.93 ENST00000539962.6
ENST00000249700.9
tropomodulin 2
chr7_+_5592805 0.91 ENST00000382361.8
fascin actin-bundling protein 1
chr11_-_44950867 0.90 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
tumor protein p53 inducible protein 11
chr1_+_64470120 0.90 ENST00000651257.2
cache domain containing 1
chr16_+_1153202 0.90 ENST00000358590.8
ENST00000638323.1
calcium voltage-gated channel subunit alpha1 H
chr5_-_39425187 0.90 ENST00000545653.5
DAB adaptor protein 2
chr4_-_142305935 0.87 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr3_+_23810436 0.86 ENST00000467766.5
ENST00000424381.5
ubiquitin conjugating enzyme E2 E1
chr9_-_122227525 0.85 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr2_-_70248598 0.85 ENST00000445587.5
ENST00000433529.7
ENST00000415783.6
TIA1 cytotoxic granule associated RNA binding protein
chr12_-_11395556 0.85 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr1_-_32336224 0.85 ENST00000329421.8
MARCKS like 1
chr2_+_27582969 0.85 ENST00000556601.5
ENST00000413371.6
ENST00000416005.6
zinc finger protein 512
chr6_+_33620329 0.84 ENST00000374316.9
inositol 1,4,5-trisphosphate receptor type 3
chr15_+_81000913 0.84 ENST00000267984.4
talin rod domain containing 1
chr18_-_55321986 0.83 ENST00000570287.6
transcription factor 4
chr3_+_111542178 0.83 ENST00000283285.10
ENST00000352690.9
CD96 molecule
chr11_+_73308237 0.83 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr17_+_1762814 0.83 ENST00000570731.5
serpin family F member 1
chr1_+_23959797 0.82 ENST00000374468.1
ENST00000334351.8
proline rich nuclear receptor coactivator 2
chr11_-_95232514 0.82 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr11_+_46381194 0.81 ENST00000533952.5
midkine
chr2_-_207166818 0.81 ENST00000423015.5
Kruppel like factor 7
chr3_-_192917832 0.81 ENST00000392452.3
Mab-21 domain containing 2
chr1_+_99646025 0.80 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr9_+_19409000 0.79 ENST00000340967.3
alkaline ceramidase 2
chr12_-_57752265 0.79 ENST00000547281.5
ENST00000257904.11
ENST00000546489.5
ENST00000552388.1
cyclin dependent kinase 4
chr11_-_125495539 0.78 ENST00000524435.1
fasciculation and elongation protein zeta 1
chr5_+_141172637 0.77 ENST00000231137.6
protocadherin beta 7
chr4_+_152936315 0.77 ENST00000511601.6
FH2 domain containing 1
chr22_+_19760714 0.77 ENST00000649276.2
T-box transcription factor 1
chr4_+_26321192 0.77 ENST00000681484.1
recombination signal binding protein for immunoglobulin kappa J region
chr17_-_81512671 0.76 ENST00000679480.1
ENST00000644774.2
ENST00000571721.6
ENST00000575842.5
ENST00000575087.5
ENST00000573283.7
ENST00000571691.6
ENST00000570382.2
actin gamma 1
chr5_-_39424966 0.76 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr14_+_22281097 0.75 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr9_-_127950716 0.75 ENST00000373084.8
family with sequence similarity 102 member A
chr12_+_8697681 0.74 ENST00000539923.5
ENST00000537189.1
ribosomal modification protein rimK like family member B
chr2_-_37672448 0.73 ENST00000611976.1
CDC42 effector protein 3
chr2_+_27583015 0.73 ENST00000379717.5
ENST00000355467.6
ENST00000505973.1
zinc finger protein 512
novel transcript
chr16_+_68539213 0.73 ENST00000570495.5
ENST00000564323.5
ENST00000562156.5
ENST00000573685.5
ENST00000563169.7
ENST00000611381.4
ZFP90 zinc finger protein
chr10_-_59362584 0.72 ENST00000618427.4
ENST00000611933.4
family with sequence similarity 13 member C
chr6_-_31815244 0.72 ENST00000375654.5
heat shock protein family A (Hsp70) member 1 like
chr6_+_125919296 0.71 ENST00000444128.2
nuclear receptor coactivator 7
chr11_-_75525925 0.70 ENST00000336898.8
glycerophosphodiester phosphodiesterase domain containing 5
chr7_+_77538059 0.70 ENST00000435495.6
protein tyrosine phosphatase non-receptor type 12
chr14_-_94770102 0.70 ENST00000238558.5
goosecoid homeobox
chr6_+_125919210 0.70 ENST00000438495.6
nuclear receptor coactivator 7
chr5_+_141187138 0.70 ENST00000316105.7
ENST00000624909.1
protocadherin beta 9
chr2_-_207167220 0.69 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr21_+_6111123 0.69 ENST00000613488.3
salt inducible kinase 1B (putative)
chr10_-_24952573 0.69 ENST00000376378.5
ENST00000376376.3
ENST00000320152.11
phosphoribosyl transferase domain containing 1
chr4_-_142305826 0.68 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr7_+_102912983 0.68 ENST00000339431.9
ENST00000249377.4
leucine rich repeat containing 17
chr12_+_8913875 0.68 ENST00000538657.5
polyhomeotic homolog 1
chrX_+_12975083 0.68 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr12_-_95217373 0.68 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FYVE, RhoGEF and PH domain containing 6
chr17_+_77287891 0.68 ENST00000449803.6
ENST00000431235.6
septin 9
chr12_+_54280842 0.67 ENST00000678077.1
ENST00000548688.5
heterogeneous nuclear ribonucleoprotein A1
chr7_+_77538027 0.67 ENST00000433369.6
ENST00000415482.6
protein tyrosine phosphatase non-receptor type 12
chr2_-_86563382 0.66 ENST00000263856.9
charged multivesicular body protein 3
chr3_-_15521675 0.66 ENST00000383788.10
ENST00000383786.9
ENST00000603808.5
collagen like tail subunit of asymmetric acetylcholinesterase
chr7_-_45088888 0.65 ENST00000490531.3
NAC alpha domain containing
chr15_+_75843438 0.64 ENST00000267938.9
ubiquitin conjugating enzyme E2 Q2
chr8_+_94641074 0.63 ENST00000423620.6
epithelial splicing regulatory protein 1
chr14_+_103123452 0.63 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr2_-_39121000 0.63 ENST00000402219.8
SOS Ras/Rac guanine nucleotide exchange factor 1
chr10_+_113751675 0.63 ENST00000369312.9
ENST00000619563.5
pleckstrin homology domain containing S1
chr3_-_128488507 0.61 ENST00000487848.5
GATA binding protein 2
chr22_+_38656627 0.60 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
1.1 4.5 GO:0032600 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
1.1 5.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.9 6.5 GO:0072011 glomerular endothelium development(GO:0072011)
0.9 2.8 GO:0070662 mast cell proliferation(GO:0070662)
0.6 3.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.6 1.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.5 2.7 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.5 1.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.5 4.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 1.9 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.4 1.3 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.4 3.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.4 1.3 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.4 7.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.4 1.1 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.4 1.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.3 1.7 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 1.7 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 4.6 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 2.9 GO:1990834 response to odorant(GO:1990834)
0.3 4.2 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 2.1 GO:0030421 defecation(GO:0030421)
0.3 1.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.3 0.8 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.3 2.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 2.7 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 0.7 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.2 0.7 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 2.9 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 1.3 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.2 1.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 0.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 2.0 GO:0001714 endodermal cell fate specification(GO:0001714)
0.2 2.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 4.9 GO:0006825 copper ion transport(GO:0006825)
0.2 1.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 2.4 GO:0009414 response to water deprivation(GO:0009414)
0.2 0.9 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.4 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 3.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 10.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 2.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.5 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.7 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.1 0.6 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 1.6 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 1.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 3.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.6 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) regulation of forebrain neuron differentiation(GO:2000977)
0.1 1.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 1.3 GO:0003307 regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.1 2.1 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.9 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.7 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 2.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.2 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.7 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 1.0 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 3.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.6 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 2.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 3.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.7 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 2.2 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.8 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 2.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 2.0 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 3.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.5 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 1.4 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.4 GO:0072675 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241) osteoclast fusion(GO:0072675)
0.1 0.9 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.7 GO:0048539 bone marrow development(GO:0048539)
0.1 0.9 GO:0009415 response to water(GO:0009415) response to hydrostatic pressure(GO:0051599)
0.1 0.3 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 6.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.3 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 4.0 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 1.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0060466 CD24 biosynthetic process(GO:0035724) activation of meiosis involved in egg activation(GO:0060466) negative regulation of monocyte extravasation(GO:2000438) regulation of CD24 biosynthetic process(GO:2000559) positive regulation of CD24 biosynthetic process(GO:2000560)
0.0 0.6 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 1.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 1.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.6 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 4.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.9 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.5 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 1.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 2.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.6 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 1.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 1.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.7 GO:0042026 protein refolding(GO:0042026)
0.0 1.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0001942 hair follicle development(GO:0001942)
0.0 0.9 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 1.3 GO:0002181 cytoplasmic translation(GO:0002181)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.7 2.1 GO:0005914 spot adherens junction(GO:0005914)
0.6 9.7 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.6 1.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.5 2.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.4 5.6 GO:0030478 actin cap(GO:0030478)
0.4 5.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3 3.0 GO:0005579 membrane attack complex(GO:0005579)
0.3 0.9 GO:0016590 ACF complex(GO:0016590)
0.3 13.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.7 GO:0031523 Myb complex(GO:0031523)
0.2 1.8 GO:0097165 nuclear stress granule(GO:0097165)
0.2 1.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 2.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 10.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 0.9 GO:0044393 microspike(GO:0044393)
0.1 4.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.3 GO:0032437 cuticular plate(GO:0032437)
0.1 2.3 GO:0071203 WASH complex(GO:0071203)
0.1 3.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 6.3 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 1.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 2.8 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 2.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.7 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:1990037 Lewy body core(GO:1990037)
0.0 1.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 4.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0043203 axon hillock(GO:0043203)
0.0 0.8 GO:0097433 dense body(GO:0097433)
0.0 1.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.4 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 1.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.5 GO:0000346 transcription export complex(GO:0000346)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 2.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.5 4.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 4.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 2.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.4 5.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 3.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 1.8 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3 4.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 3.1 GO:0048495 Roundabout binding(GO:0048495)
0.3 2.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 1.6 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 0.7 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 6.5 GO:0005523 tropomyosin binding(GO:0005523)
0.2 2.7 GO:0016015 morphogen activity(GO:0016015)
0.2 0.8 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.2 1.7 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 0.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 1.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 0.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.2 10.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 2.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.5 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 3.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 11.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.1 GO:0031005 filamin binding(GO:0031005)
0.1 1.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 4.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.1 3.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 2.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 3.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.3 GO:0000150 recombinase activity(GO:0000150)
0.1 3.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.6 GO:0035198 miRNA binding(GO:0035198)
0.0 1.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 3.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 3.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 6.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 5.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 6.7 GO:0003823 antigen binding(GO:0003823)
0.0 1.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.0 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 1.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 3.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 6.1 GO:0015631 tubulin binding(GO:0015631)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 2.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 11.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 7.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 6.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 6.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.1 PID FGF PATHWAY FGF signaling pathway
0.0 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 4.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 5.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 7.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 3.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 2.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 5.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 7.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 10.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 12.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 8.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes