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Illumina Body Map 2 (GSE30611)

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Results for SOX7

Z-value: 0.81

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
SOX7
ENSG00000171056.8 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX7hg38_v1_chr8_-_10730498_10730525-0.494.8e-03Click!
PINX1hg38_v1_chr8_-_10839818_10839855-0.431.4e-02Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_26067622 2.70 ENST00000374272.4
TRIM63
tripartite motif containing 63
chr4_-_176269213 1.94 ENST00000296525.7
ASB5
ankyrin repeat and SOCS box containing 5
chr1_-_89272775 1.63 ENST00000443807.1
GBP5
guanylate binding protein 5
chr8_+_28338640 1.59 ENST00000522209.1
PNOC
prepronociceptin
chr16_+_28292485 1.58 ENST00000341901.5
SBK1
SH3 domain binding kinase 1
chr14_-_106117159 1.42 ENST00000390601.3
IGHV3-11
immunoglobulin heavy variable 3-11
chr1_+_158931539 1.41 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
PYHIN1
pyrin and HIN domain family member 1
chr16_-_20352707 1.34 ENST00000396134.6
ENST00000573567.5
ENST00000570757.5
ENST00000396138.9
ENST00000571174.5
ENST00000576688.2
UMOD
uromodulin
chr16_-_20352857 1.30 ENST00000577168.2
UMOD
uromodulin
chr2_-_89222461 1.20 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr22_+_22720615 1.15 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr16_+_33009175 1.14 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr6_+_150368997 1.12 ENST00000392255.7
ENST00000500320.7
ENST00000344419.8
IYD
iodotyrosine deiodinase
chr17_-_35880350 1.06 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
CCL5
C-C motif chemokine ligand 5
chr2_-_89100352 1.03 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr6_+_150368892 1.02 ENST00000229447.9
ENST00000392256.6
IYD
iodotyrosine deiodinase
chr16_-_33845229 0.99 ENST00000569103.2
IGHV3OR16-17
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr19_-_38426195 0.96 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RASGRP4
RAS guanyl releasing protein 4
chr4_+_76074701 0.84 ENST00000355810.9
ENST00000349321.7
ART3
ADP-ribosyltransferase 3 (inactive)
chr15_+_63122561 0.79 ENST00000557972.1
LACTB
lactamase beta
chr6_+_42563981 0.79 ENST00000372899.6
ENST00000372901.2
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr2_+_86907953 0.78 ENST00000409776.6
RGPD1
RANBP2 like and GRIP domain containing 1
chr12_-_56299974 0.70 ENST00000547298.5
ENST00000551936.5
ENST00000551253.5
ENST00000551473.5
CS
citrate synthase
chr4_-_122456725 0.68 ENST00000226730.5
IL2
interleukin 2
chr6_+_143843316 0.66 ENST00000367576.6
LTV1
LTV1 ribosome biogenesis factor
chr12_-_89656093 0.66 ENST00000359142.7
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr6_+_116399395 0.64 ENST00000644499.1
ENSG00000285446.1
novel protein
chr13_-_46020487 0.64 ENST00000464597.2
ZC3H13
zinc finger CCCH-type containing 13
chr19_-_38426162 0.63 ENST00000587738.2
ENST00000586305.5
RASGRP4
RAS guanyl releasing protein 4
chr12_-_89656051 0.61 ENST00000261173.6
ATP2B1
ATPase plasma membrane Ca2+ transporting 1
chr12_-_10420550 0.56 ENST00000381903.2
ENST00000396439.7
KLRC3
killer cell lectin like receptor C3
chr13_-_37059432 0.54 ENST00000464744.5
SUPT20H
SPT20 homolog, SAGA complex component
chr5_+_162067858 0.51 ENST00000361925.9
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chrX_+_131083706 0.51 ENST00000370921.1
ARHGAP36
Rho GTPase activating protein 36
chr3_-_71306012 0.47 ENST00000649431.1
ENST00000610810.5
FOXP1
forkhead box P1
chr4_+_146214515 0.46 ENST00000636502.1
REELD1
reeler domain containing 1
chr14_+_60245744 0.45 ENST00000325642.7
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent 1A
chr5_+_162067764 0.44 ENST00000639213.2
ENST00000414552.6
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr11_+_35186820 0.43 ENST00000531110.6
ENST00000525685.6
CD44
CD44 molecule (Indian blood group)
chr3_-_71305986 0.42 ENST00000647614.1
FOXP1
forkhead box P1
chr5_+_162067500 0.40 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr11_+_5689691 0.39 ENST00000425490.5
TRIM22
tripartite motif containing 22
chr1_-_186461089 0.38 ENST00000391997.3
PDC
phosducin
chr1_-_158426237 0.37 ENST00000641042.1
OR10K2
olfactory receptor family 10 subfamily K member 2
chr5_+_162067458 0.31 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_+_29100609 0.29 ENST00000377171.3
OR2J1
olfactory receptor family 2 subfamily J member 1
chr19_+_37346316 0.27 ENST00000591134.5
ZNF875
zinc finger protein 875
chr17_+_82900542 0.27 ENST00000574422.1
TBCD
tubulin folding cofactor D
chr7_+_134565098 0.26 ENST00000652743.1
AKR1B15
aldo-keto reductase family 1 member B15
chr10_+_95911254 0.24 ENST00000636965.1
CC2D2B
coiled-coil and C2 domain containing 2B
chr11_-_6003194 0.24 ENST00000330728.4
ENST00000641279.1
OR56A4
olfactory receptor family 56 subfamily A member 4
chr17_-_30334050 0.23 ENST00000328886.5
ENST00000538566.6
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr12_+_55492378 0.23 ENST00000548615.1
OR6C68
olfactory receptor family 6 subfamily C member 68
chr7_+_141918817 0.23 ENST00000548136.1
OR9A4
olfactory receptor family 9 subfamily A member 4
chr11_+_5754243 0.23 ENST00000641350.2
OR52N4
olfactory receptor family 52 subfamily N member 4
chr17_-_67239800 0.22 ENST00000579861.1
HELZ
helicase with zinc finger
chr11_-_62707331 0.22 ENST00000533982.1
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin
chr3_+_98463201 0.19 ENST00000642057.1
OR5K1
olfactory receptor family 5 subfamily K member 1
chr14_-_23104845 0.19 ENST00000642668.1
ENST00000644000.1
LMLN2
leishmanolysin like peptidase 2
chr11_+_7597182 0.19 ENST00000528883.5
PPFIBP2
PPFIA binding protein 2
chr12_-_56934403 0.16 ENST00000293502.2
SDR9C7
short chain dehydrogenase/reductase family 9C member 7
chr18_+_35241027 0.16 ENST00000330501.12
ENST00000601719.1
ENST00000591206.5
ENST00000261333.10
ENST00000355632.8
ENST00000585800.1
ZNF397
zinc finger protein 397
chr4_+_74308492 0.15 ENST00000502358.5
ENST00000503098.5
ENST00000505212.5
ENST00000509145.5
ENST00000514968.5
EPGN
epithelial mitogen
chr12_-_10998304 0.15 ENST00000538986.2
TAS2R20
taste 2 receptor member 20
chr8_-_19602484 0.15 ENST00000454498.6
ENST00000520003.5
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr6_-_111483700 0.15 ENST00000435970.5
ENST00000358835.7
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chr1_-_152089062 0.15 ENST00000368806.2
TCHHL1
trichohyalin like 1
chr19_+_34926892 0.14 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
ZNF30
zinc finger protein 30
chr8_+_12945667 0.14 ENST00000524591.7
TRMT9B
tRNA methyltransferase 9B (putative)
chr19_-_5784599 0.13 ENST00000390672.2
ENST00000419421.3
PRR22
proline rich 22
chr1_+_247738615 0.12 ENST00000283225.2
OR14K1
olfactory receptor family 14 subfamily K member 1
chr21_-_14546297 0.11 ENST00000400566.6
ENST00000400564.5
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_200027731 0.10 ENST00000447034.1
NR5A2
nuclear receptor subfamily 5 group A member 2
chr3_-_122564577 0.10 ENST00000477522.6
ENST00000360356.6
PARP9
poly(ADP-ribose) polymerase family member 9
chr12_-_123243998 0.09 ENST00000545406.1
MPHOSPH9
M-phase phosphoprotein 9
chr1_+_100133186 0.06 ENST00000370139.1
TRMT13
tRNA methyltransferase 13 homolog
chr10_+_24449426 0.06 ENST00000307544.10
KIAA1217
KIAA1217
chr3_-_36993103 0.06 ENST00000322716.8
EPM2AIP1
EPM2A interacting protein 1
chr7_-_138755892 0.05 ENST00000644341.1
ENST00000478480.2
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr2_-_105396750 0.05 ENST00000447958.1
FHL2
four and a half LIM domains 2
chr7_+_100120026 0.04 ENST00000483756.5
CNPY4
canopy FGF signaling regulator 4
chr3_-_161371501 0.03 ENST00000497137.1
SPTSSB
serine palmitoyltransferase small subunit B
chr4_-_47981535 0.03 ENST00000402813.9
CNGA1
cyclic nucleotide gated channel subunit alpha 1
chr13_+_94601830 0.02 ENST00000376958.5
GPR180
G protein-coupled receptor 180
chr8_-_86069662 0.02 ENST00000276616.3
PSKH2
protein serine kinase H2
chr10_-_12042771 0.01 ENST00000357604.10
UPF2
UPF2 regulator of nonsense mediated mRNA decay
chr4_+_74308487 0.00 ENST00000332112.8
EPGN
epithelial mitogen

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.5 2.7 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.3 1.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 1.6 GO:0032621 interleukin-18 production(GO:0032621)
0.2 0.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 2.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 1.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.7 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.9 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 5.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0034448 EGO complex(GO:0034448)
0.0 2.9 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 2.7 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.7 GO:0060170 ciliary membrane(GO:0060170)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 0.7 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 1.6 GO:0001515 opioid peptide activity(GO:0001515)
0.2 1.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 2.6 GO:0019864 IgG binding(GO:0019864)
0.1 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 2.7 GO:0031432 titin binding(GO:0031432)
0.1 1.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.8 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 5.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 5.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling