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Illumina Body Map 2 (GSE30611)

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Results for SOX7

Z-value: 0.81

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
ENSG00000171056.8 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX7hg38_v1_chr8_-_10730498_10730525-0.494.8e-03Click!
PINX1hg38_v1_chr8_-_10839818_10839855-0.431.4e-02Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_26067622 2.70 ENST00000374272.4
tripartite motif containing 63
chr4_-_176269213 1.94 ENST00000296525.7
ankyrin repeat and SOCS box containing 5
chr1_-_89272775 1.63 ENST00000443807.1
guanylate binding protein 5
chr8_+_28338640 1.59 ENST00000522209.1
prepronociceptin
chr16_+_28292485 1.58 ENST00000341901.5
SH3 domain binding kinase 1
chr14_-_106117159 1.42 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr1_+_158931539 1.41 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
pyrin and HIN domain family member 1
chr16_-_20352707 1.34 ENST00000396134.6
ENST00000573567.5
ENST00000570757.5
ENST00000396138.9
ENST00000571174.5
ENST00000576688.2
uromodulin
chr16_-_20352857 1.30 ENST00000577168.2
uromodulin
chr2_-_89222461 1.20 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr22_+_22720615 1.15 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr16_+_33009175 1.14 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr6_+_150368997 1.12 ENST00000392255.7
ENST00000500320.7
ENST00000344419.8
iodotyrosine deiodinase
chr17_-_35880350 1.06 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr2_-_89100352 1.03 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr6_+_150368892 1.02 ENST00000229447.9
ENST00000392256.6
iodotyrosine deiodinase
chr16_-_33845229 0.99 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr19_-_38426195 0.96 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr4_+_76074701 0.84 ENST00000355810.9
ENST00000349321.7
ADP-ribosyltransferase 3 (inactive)
chr15_+_63122561 0.79 ENST00000557972.1
lactamase beta
chr6_+_42563981 0.79 ENST00000372899.6
ENST00000372901.2
ubiquitin protein ligase E3 component n-recognin 2
chr2_+_86907953 0.78 ENST00000409776.6
RANBP2 like and GRIP domain containing 1
chr12_-_56299974 0.70 ENST00000547298.5
ENST00000551936.5
ENST00000551253.5
ENST00000551473.5
citrate synthase
chr4_-_122456725 0.68 ENST00000226730.5
interleukin 2
chr6_+_143843316 0.66 ENST00000367576.6
LTV1 ribosome biogenesis factor
chr12_-_89656093 0.66 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr6_+_116399395 0.64 ENST00000644499.1
novel protein
chr13_-_46020487 0.64 ENST00000464597.2
zinc finger CCCH-type containing 13
chr19_-_38426162 0.63 ENST00000587738.2
ENST00000586305.5
RAS guanyl releasing protein 4
chr12_-_89656051 0.61 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr12_-_10420550 0.56 ENST00000381903.2
ENST00000396439.7
killer cell lectin like receptor C3
chr13_-_37059432 0.54 ENST00000464744.5
SPT20 homolog, SAGA complex component
chr5_+_162067858 0.51 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chrX_+_131083706 0.51 ENST00000370921.1
Rho GTPase activating protein 36
chr3_-_71306012 0.47 ENST00000649431.1
ENST00000610810.5
forkhead box P1
chr4_+_146214515 0.46 ENST00000636502.1
reeler domain containing 1
chr14_+_60245744 0.45 ENST00000325642.7
protein phosphatase, Mg2+/Mn2+ dependent 1A
chr5_+_162067764 0.44 ENST00000639213.2
ENST00000414552.6
gamma-aminobutyric acid type A receptor subunit gamma2
chr11_+_35186820 0.43 ENST00000531110.6
ENST00000525685.6
CD44 molecule (Indian blood group)
chr3_-_71305986 0.42 ENST00000647614.1
forkhead box P1
chr5_+_162067500 0.40 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr11_+_5689691 0.39 ENST00000425490.5
tripartite motif containing 22
chr1_-_186461089 0.38 ENST00000391997.3
phosducin
chr1_-_158426237 0.37 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr5_+_162067458 0.31 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_+_29100609 0.29 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr19_+_37346316 0.27 ENST00000591134.5
zinc finger protein 875
chr17_+_82900542 0.27 ENST00000574422.1
tubulin folding cofactor D
chr7_+_134565098 0.26 ENST00000652743.1
aldo-keto reductase family 1 member B15
chr10_+_95911254 0.24 ENST00000636965.1
coiled-coil and C2 domain containing 2B
chr11_-_6003194 0.24 ENST00000330728.4
ENST00000641279.1
olfactory receptor family 56 subfamily A member 4
chr17_-_30334050 0.23 ENST00000328886.5
ENST00000538566.6
transmembrane and immunoglobulin domain containing 1
chr12_+_55492378 0.23 ENST00000548615.1
olfactory receptor family 6 subfamily C member 68
chr7_+_141918817 0.23 ENST00000548136.1
olfactory receptor family 9 subfamily A member 4
chr11_+_5754243 0.23 ENST00000641350.2
olfactory receptor family 52 subfamily N member 4
chr17_-_67239800 0.22 ENST00000579861.1
helicase with zinc finger
chr11_-_62707331 0.22 ENST00000533982.1
BSCL2 lipid droplet biogenesis associated, seipin
chr3_+_98463201 0.19 ENST00000642057.1
olfactory receptor family 5 subfamily K member 1
chr14_-_23104845 0.19 ENST00000642668.1
ENST00000644000.1
leishmanolysin like peptidase 2
chr11_+_7597182 0.19 ENST00000528883.5
PPFIA binding protein 2
chr12_-_56934403 0.16 ENST00000293502.2
short chain dehydrogenase/reductase family 9C member 7
chr18_+_35241027 0.16 ENST00000330501.12
ENST00000601719.1
ENST00000591206.5
ENST00000261333.10
ENST00000355632.8
ENST00000585800.1
zinc finger protein 397
chr4_+_74308492 0.15 ENST00000502358.5
ENST00000503098.5
ENST00000505212.5
ENST00000509145.5
ENST00000514968.5
epithelial mitogen
chr12_-_10998304 0.15 ENST00000538986.2
taste 2 receptor member 20
chr8_-_19602484 0.15 ENST00000454498.6
ENST00000520003.5
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr6_-_111483700 0.15 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr1_-_152089062 0.15 ENST00000368806.2
trichohyalin like 1
chr19_+_34926892 0.14 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
zinc finger protein 30
chr8_+_12945667 0.14 ENST00000524591.7
tRNA methyltransferase 9B (putative)
chr19_-_5784599 0.13 ENST00000390672.2
ENST00000419421.3
proline rich 22
chr1_+_247738615 0.12 ENST00000283225.2
olfactory receptor family 14 subfamily K member 1
chr21_-_14546297 0.11 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_200027731 0.10 ENST00000447034.1
nuclear receptor subfamily 5 group A member 2
chr3_-_122564577 0.10 ENST00000477522.6
ENST00000360356.6
poly(ADP-ribose) polymerase family member 9
chr12_-_123243998 0.09 ENST00000545406.1
M-phase phosphoprotein 9
chr1_+_100133186 0.06 ENST00000370139.1
tRNA methyltransferase 13 homolog
chr10_+_24449426 0.06 ENST00000307544.10
KIAA1217
chr3_-_36993103 0.06 ENST00000322716.8
EPM2A interacting protein 1
chr7_-_138755892 0.05 ENST00000644341.1
ENST00000478480.2
ATPase H+ transporting V0 subunit a4
chr2_-_105396750 0.05 ENST00000447958.1
four and a half LIM domains 2
chr7_+_100120026 0.04 ENST00000483756.5
canopy FGF signaling regulator 4
chr3_-_161371501 0.03 ENST00000497137.1
serine palmitoyltransferase small subunit B
chr4_-_47981535 0.03 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr13_+_94601830 0.02 ENST00000376958.5
G protein-coupled receptor 180
chr8_-_86069662 0.02 ENST00000276616.3
protein serine kinase H2
chr10_-_12042771 0.01 ENST00000357604.10
UPF2 regulator of nonsense mediated mRNA decay
chr4_+_74308487 0.00 ENST00000332112.8
epithelial mitogen

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.5 2.7 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.3 1.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 1.6 GO:0032621 interleukin-18 production(GO:0032621)
0.2 0.8 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 2.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 1.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.7 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.9 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 5.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0034448 EGO complex(GO:0034448)
0.0 2.9 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 2.7 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.7 GO:0060170 ciliary membrane(GO:0060170)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 0.7 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.2 1.6 GO:0001515 opioid peptide activity(GO:0001515)
0.2 1.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 2.6 GO:0019864 IgG binding(GO:0019864)
0.1 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 2.7 GO:0031432 titin binding(GO:0031432)
0.1 1.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.8 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 5.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 5.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling