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Illumina Body Map 2 (GSE30611)

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Results for SPI1

Z-value: 4.92

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Transcription factors associated with SPI1

Gene Symbol Gene ID Gene Info
ENSG00000066336.12 Spi-1 proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPI1hg38_v1_chr11_-_47378527_473785550.904.3e-12Click!

Activity profile of SPI1 motif

Sorted Z-values of SPI1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_198638968 36.29 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr1_-_167518583 29.43 ENST00000392122.3
CD247 molecule
chr1_+_198638723 28.31 ENST00000643513.1
protein tyrosine phosphatase receptor type C
chr1_-_167518521 28.18 ENST00000362089.10
CD247 molecule
chr1_+_198639162 25.45 ENST00000418674.1
protein tyrosine phosphatase receptor type C
chr6_-_32192845 25.23 ENST00000487761.5
G protein signaling modulator 3
chr11_+_60455839 25.15 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr1_-_206921867 25.14 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr6_-_32192630 24.88 ENST00000375040.8
G protein signaling modulator 3
chr1_+_198638457 24.70 ENST00000367379.6
protein tyrosine phosphatase receptor type C
chr7_-_44979003 24.70 ENST00000258787.12
ENST00000648014.1
myosin IG
chr1_-_206921987 24.26 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr1_-_150765735 24.20 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr2_+_233059838 20.53 ENST00000359570.9
inositol polyphosphate-5-phosphatase D
chr2_+_233060295 19.64 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr22_+_37282464 18.77 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
cytohesin 4
chr5_-_170297746 18.55 ENST00000046794.10
lymphocyte cytosolic protein 2
chr11_-_67437670 18.38 ENST00000326294.4
protein tyrosine phosphatase receptor type C associated protein
chr5_-_67196791 18.22 ENST00000256447.5
CD180 molecule
chr16_-_30382805 18.11 ENST00000321367.7
ENST00000652617.1
septin 1
chr6_+_144659814 18.06 ENST00000367525.3
utrophin
chr2_+_68774782 17.93 ENST00000409030.7
ENST00000409220.5
Rho GTPase activating protein 25
chr6_+_31586124 17.74 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
leukocyte specific transcript 1
chr19_-_8577405 17.70 ENST00000596675.1
ENST00000644032.2
ENST00000613525.4
myosin IF
chr13_-_46182136 17.05 ENST00000323076.7
lymphocyte cytosolic protein 1
chr16_+_30472700 17.02 ENST00000358164.9
integrin subunit alpha L
chr19_+_49335396 16.89 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr1_-_150765785 16.69 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr1_-_183590876 16.32 ENST00000367536.5
neutrophil cytosolic factor 2
chrX_+_129779930 16.27 ENST00000356892.4
SAM and SH3 domain containing 3
chr1_-_183590596 16.22 ENST00000418089.5
ENST00000413720.5
neutrophil cytosolic factor 2
chr12_+_54497712 16.19 ENST00000293373.11
NCK associated protein 1 like
chr15_+_81296913 16.02 ENST00000394652.6
interleukin 16
chr16_-_29745951 15.93 ENST00000329410.4
chromosome 16 open reading frame 54
chr1_-_183590439 15.46 ENST00000367535.8
neutrophil cytosolic factor 2
chr16_+_30472733 15.44 ENST00000356798.11
ENST00000433423.2
integrin subunit alpha L
chr5_+_58491427 15.34 ENST00000396776.6
ENST00000502276.6
ENST00000511930.2
GRB2 binding adaptor protein, transmembrane
chr11_+_118304721 15.30 ENST00000361763.9
CD3e molecule
chr7_+_50304693 15.29 ENST00000331340.8
ENST00000413698.5
ENST00000612658.4
ENST00000359197.9
ENST00000349824.8
ENST00000343574.9
ENST00000357364.8
ENST00000440768.6
ENST00000346667.8
ENST00000615491.4
IKAROS family zinc finger 1
chr11_+_118304881 15.21 ENST00000528600.1
CD3e molecule
chr19_-_6481769 15.14 ENST00000381480.7
ENST00000543576.5
ENST00000590173.5
DENN domain containing 1C
chr1_-_161069666 14.99 ENST00000368016.7
Rho GTPase activating protein 30
chr19_+_41877267 14.99 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr22_-_37244417 14.80 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr11_-_118212885 14.75 ENST00000524477.5
junction adhesion molecule like
chr17_+_45221854 14.60 ENST00000331495.8
formin like 1
chr17_+_45221993 14.38 ENST00000328118.7
formin like 1
chr11_-_47378391 14.32 ENST00000227163.8
Spi-1 proto-oncogene
chr11_-_47378527 14.28 ENST00000378538.8
Spi-1 proto-oncogene
chr2_+_68774921 14.22 ENST00000497079.5
Rho GTPase activating protein 25
chr10_-_70602759 14.17 ENST00000373209.2
perforin 1
chr10_-_70602731 14.00 ENST00000441259.2
perforin 1
chr4_+_99816797 13.88 ENST00000512369.2
ENST00000296414.11
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr11_-_47378494 13.86 ENST00000533030.1
Spi-1 proto-oncogene
chr11_+_67404077 13.84 ENST00000542590.2
ENST00000312390.9
TBC1 domain family member 10C
chr7_+_106865263 13.82 ENST00000440650.6
ENST00000496166.6
ENST00000473541.5
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr11_+_61102465 13.62 ENST00000347785.8
ENST00000544014.1
CD5 molecule
chr5_+_58491451 13.59 ENST00000513924.2
ENST00000515443.2
GRB2 binding adaptor protein, transmembrane
chr16_-_21652598 13.54 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr7_-_116030750 13.52 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr11_-_47378479 13.22 ENST00000533968.1
Spi-1 proto-oncogene
chr11_+_128693887 13.22 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr14_-_22815421 13.17 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chrX_-_47629845 13.16 ENST00000469388.1
ENST00000396992.8
ENST00000377005.6
complement factor properdin
chr12_+_6946468 13.08 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr11_-_3840829 12.98 ENST00000396978.1
ras homolog family member G
chr9_-_134917872 12.92 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr17_+_49210699 12.89 ENST00000225941.6
ABI family member 3
chr5_+_35856883 12.88 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr11_+_128694052 12.82 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr10_-_70602687 12.72 ENST00000638674.1
perforin 1
chr4_-_152679984 12.48 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr1_-_206923183 12.46 ENST00000525793.5
Fc fragment of IgM receptor
chr17_+_49210387 12.44 ENST00000419580.6
ABI family member 3
chr9_+_273026 12.43 ENST00000682249.1
ENST00000453981.5
ENST00000487230.5
ENST00000469391.5
dedicator of cytokinesis 8
chr16_+_28985043 12.40 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
linker for activation of T cells
chr16_+_29662923 12.38 ENST00000395389.2
sialophorin
chr6_+_31586269 12.31 ENST00000438075.7
leukocyte specific transcript 1
chr1_+_32251239 12.20 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK proto-oncogene, Src family tyrosine kinase
chr1_+_110873135 11.98 ENST00000271324.6
CD53 molecule
chr5_+_169637241 11.85 ENST00000520908.7
dedicator of cytokinesis 2
chr9_+_92963961 11.84 ENST00000416701.6
FYVE, RhoGEF and PH domain containing 3
chr1_-_206923242 11.81 ENST00000529560.1
Fc fragment of IgM receptor
chr8_+_55879818 11.77 ENST00000520220.6
ENST00000519728.6
LYN proto-oncogene, Src family tyrosine kinase
chrX_-_71111448 11.72 ENST00000456850.6
ENST00000473378.1
ENST00000374202.7
ENST00000374188.7
interleukin 2 receptor subunit gamma
chr1_-_161069857 11.70 ENST00000368013.8
Rho GTPase activating protein 30
chr1_+_153357846 11.69 ENST00000368738.4
S100 calcium binding protein A9
chr14_-_22815801 11.59 ENST00000397532.9
solute carrier family 7 member 7
chr1_+_9651723 11.59 ENST00000377346.9
ENST00000536656.5
ENST00000628140.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr11_-_3840942 11.56 ENST00000351018.5
ras homolog family member G
chr1_-_161069962 11.52 ENST00000368015.1
Rho GTPase activating protein 30
chr14_-_22815856 11.45 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr1_+_32274111 11.38 ENST00000619559.4
ENST00000461712.6
ENST00000373562.7
ENST00000477031.6
ENST00000373557.6
ENST00000333070.4
LCK proto-oncogene, Src family tyrosine kinase
chr12_-_9607903 11.35 ENST00000229402.4
killer cell lectin like receptor B1
chr6_-_159045104 11.33 ENST00000326965.7
T cell activation RhoGTPase activating protein
chr2_+_203936755 11.24 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr6_-_159044980 11.20 ENST00000367066.8
T cell activation RhoGTPase activating protein
chr6_+_31575557 11.13 ENST00000449264.3
tumor necrosis factor
chr11_+_65639860 11.09 ENST00000527525.5
signal-induced proliferation-associated 1
chr19_-_35908247 11.07 ENST00000585901.6
ENST00000544690.6
ENST00000424586.7
ENST00000262629.9
ENST00000589517.1
transmembrane immune signaling adaptor TYROBP
chr15_-_40307910 11.06 ENST00000543785.3
ENST00000260402.8
phospholipase C beta 2
chr1_-_202160577 11.06 ENST00000629151.2
ENST00000476061.5
ENST00000464870.5
ENST00000467283.5
ENST00000435759.6
ENST00000486116.5
ENST00000477625.5
protein tyrosine phosphatase non-receptor type 7
chr17_-_31314040 11.05 ENST00000330927.5
ecotropic viral integration site 2B
chr22_-_37149900 10.94 ENST00000216223.10
interleukin 2 receptor subunit beta
chr4_+_67558719 10.86 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr7_-_116030735 10.78 ENST00000393485.5
transcription factor EC
chr11_+_67403887 10.76 ENST00000526387.5
TBC1 domain family member 10C
chr8_-_132760548 10.73 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
transmembrane protein 71
chr15_+_76995118 10.73 ENST00000558012.6
ENST00000379595.7
proline-serine-threonine phosphatase interacting protein 1
chr17_+_4715438 10.73 ENST00000571206.1
arrestin beta 2
chr9_-_114387973 10.70 ENST00000374088.8
AT-hook transcription factor
chr11_+_60971668 10.68 ENST00000313421.11
CD6 molecule
chr17_-_31314066 10.65 ENST00000577894.1
ecotropic viral integration site 2B
chr17_+_78130759 10.60 ENST00000590426.1
ENST00000318430.10
ENST00000590799.5
ENST00000589691.1
transmembrane channel like 8
chr2_-_197310646 10.56 ENST00000647377.1
ankyrin repeat domain 44
chr2_-_174634566 10.54 ENST00000392547.6
WAS/WASL interacting protein family member 1
chr10_-_6062290 10.53 ENST00000256876.10
ENST00000379954.5
interleukin 2 receptor subunit alpha
chr20_+_24949256 10.49 ENST00000480798.2
cystatin F
chr2_-_197310767 10.46 ENST00000282272.15
ENST00000409153.5
ENST00000409919.5
ankyrin repeat domain 44
chrX_+_48683763 10.40 ENST00000376701.5
WASP actin nucleation promoting factor
chr2_+_68734861 10.37 ENST00000467265.5
Rho GTPase activating protein 25
chr6_-_42048648 10.32 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr6_-_159045010 10.21 ENST00000338313.5
T cell activation RhoGTPase activating protein
chr16_+_28985251 10.20 ENST00000360872.9
ENST00000566177.5
linker for activation of T cells
chrX_+_136648138 10.10 ENST00000370629.7
CD40 ligand
chr2_-_191847068 10.10 ENST00000304141.5
caveolae associated protein 2
chr2_+_68734773 10.08 ENST00000409202.8
Rho GTPase activating protein 25
chr12_-_53207241 10.02 ENST00000267082.10
ENST00000549086.2
integrin subunit beta 7
chr17_+_74466627 10.02 ENST00000360141.8
ENST00000392625.7
ENST00000310828.9
ENST00000361933.7
CD300a molecule
chrX_+_78945332 10.00 ENST00000544091.1
ENST00000171757.3
P2Y receptor family member 10
chr14_-_22815493 9.99 ENST00000555911.1
solute carrier family 7 member 7
chr20_-_64079906 9.97 ENST00000332298.9
regulator of G protein signaling 19
chr3_-_121660892 9.96 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr22_-_37244237 9.95 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr3_-_183555696 9.94 ENST00000341319.8
kelch like family member 6
chr4_-_163613505 9.88 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr6_-_6320642 9.84 ENST00000451619.1
ENST00000264870.8
coagulation factor XIII A chain
chr12_-_53207271 9.77 ENST00000552972.5
ENST00000422257.7
integrin subunit beta 7
chr6_+_31587049 9.65 ENST00000376089.6
ENST00000396112.6
leukocyte specific transcript 1
chr15_-_40307825 9.60 ENST00000456256.6
ENST00000557821.5
phospholipase C beta 2
chr2_+_37344594 9.59 ENST00000404976.5
ENST00000338415.8
glutaminyl-peptide cyclotransferase
chr22_+_36860973 9.55 ENST00000447071.5
ENST00000397147.7
ENST00000248899.11
neutrophil cytosolic factor 4
chr3_-_46208304 9.52 ENST00000296140.4
C-C motif chemokine receptor 1
chr19_+_35902486 9.52 ENST00000246551.9
ENST00000437550.2
hematopoietic cell signal transducer
chr16_+_28984795 9.49 ENST00000395461.7
linker for activation of T cells
chr17_-_49210567 9.39 ENST00000507680.6
G protein subunit gamma transducin 2
chr1_+_203765168 9.30 ENST00000367217.5
ENST00000442561.7
lymphocyte transmembrane adaptor 1
chr5_-_39270623 9.29 ENST00000512138.1
ENST00000646045.2
FYN binding protein 1
chr6_+_31587002 9.27 ENST00000376090.6
leukocyte specific transcript 1
chr10_-_6062349 9.24 ENST00000379959.8
interleukin 2 receptor subunit alpha
chr17_+_7558296 9.21 ENST00000438470.5
ENST00000436057.5
TNF superfamily member 13
chr11_+_60971777 9.20 ENST00000542157.5
ENST00000433107.6
ENST00000352009.9
ENST00000452451.6
CD6 molecule
chr14_-_34874887 9.19 ENST00000382422.6
bromodomain adjacent to zinc finger domain 1A
chr12_-_14961610 9.16 ENST00000542276.1
Rho GDP dissociation inhibitor beta
chr12_-_51324652 9.15 ENST00000544402.5
bridging integrator 2
chr12_-_14961559 9.15 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr1_+_161706949 9.08 ENST00000350710.3
ENST00000367949.6
ENST00000367959.6
ENST00000540521.5
ENST00000546024.5
ENST00000674251.1
ENST00000674323.1
Fc receptor like A
chr17_-_48545077 9.06 ENST00000330070.6
homeobox B2
chr1_-_111204343 9.04 ENST00000369752.5
DENN domain containing 2D
chr17_+_74466386 9.02 ENST00000648095.1
CD300a molecule
chr16_+_28494634 8.95 ENST00000564831.6
ENST00000431282.2
apolipoprotein B receptor
chr17_-_44389594 8.92 ENST00000262407.6
integrin subunit alpha 2b
chr15_-_79971164 8.89 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr2_+_143129379 8.87 ENST00000295095.11
Rho GTPase activating protein 15
chr5_+_177357834 8.86 ENST00000408923.8
regulator of G protein signaling 14
chr9_-_114388020 8.83 ENST00000312033.3
AT-hook transcription factor
chr11_-_58575846 8.81 ENST00000395074.7
leupaxin
chr7_+_74773962 8.79 ENST00000289473.10
neutrophil cytosolic factor 1
chr20_-_64079479 8.76 ENST00000395042.2
regulator of G protein signaling 19
chr1_-_161550591 8.73 ENST00000367967.7
ENST00000436743.6
ENST00000442336.1
Fc fragment of IgG receptor IIIa
chr12_-_51324138 8.73 ENST00000452142.7
bridging integrator 2
chr4_-_108167784 8.71 ENST00000438313.6
lymphoid enhancer binding factor 1
chrX_+_79144664 8.71 ENST00000645147.2
G protein-coupled receptor 174
chrX_+_136648214 8.67 ENST00000370628.2
CD40 ligand
chr11_+_64340191 8.64 ENST00000356786.10
coiled-coil domain containing 88B
chr12_-_51324164 8.59 ENST00000615107.6
bridging integrator 2
chr2_-_64144411 8.57 ENST00000358912.5
pellino E3 ubiquitin protein ligase 1
chr19_+_6772699 8.57 ENST00000602142.6
ENST00000304076.6
ENST00000596764.5
vav guanine nucleotide exchange factor 1
chr4_-_40629842 8.55 ENST00000295971.12
RNA binding motif protein 47
chr10_+_48684859 8.52 ENST00000360890.6
ENST00000325239.11
WDFY family member 4
chr20_+_3786772 8.52 ENST00000344256.10
ENST00000379598.9
cell division cycle 25B
chr1_+_112619824 8.44 ENST00000263168.4
capping actin protein of muscle Z-line subunit alpha 1
chr8_+_27325516 8.43 ENST00000346049.10
ENST00000420218.3
protein tyrosine kinase 2 beta
chr22_-_30266839 8.42 ENST00000403463.1
ENST00000215781.3
oncostatin M
chr9_+_117704168 8.41 ENST00000472304.2
ENST00000394487.5
toll like receptor 4
chr20_+_59019397 8.40 ENST00000217133.2
tubulin beta 1 class VI
chrX_-_154751017 8.39 ENST00000369575.7
ENST00000369568.8
ENST00000424127.3
GRB2 associated binding protein 3
chr21_-_14546297 8.35 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr19_+_41883173 8.30 ENST00000599846.5
ENST00000354532.8
ENST00000347545.8
Rho guanine nucleotide exchange factor 1
chr6_+_32844108 8.26 ENST00000458296.2
ENST00000413039.6
ENST00000412095.1
ENST00000395330.5
PSMB8 antisense RNA 1 (head to head)
proteasome 20S subunit beta 9
chr6_-_32843994 8.16 ENST00000395339.7
ENST00000374882.8
proteasome 20S subunit beta 8
chr16_+_28985095 8.15 ENST00000454369.6
linker for activation of T cells
chr12_+_85874287 8.14 ENST00000551529.5
ENST00000256010.7
neurotensin
chr19_+_35449584 8.11 ENST00000246549.2
free fatty acid receptor 2
chr17_-_74623730 8.06 ENST00000392619.2
CD300e molecule
chr5_+_136047319 8.03 ENST00000508767.5
ENST00000604555.5
transforming growth factor beta induced
chr2_+_85577540 7.94 ENST00000263864.10
ENST00000409760.1
vesicle associated membrane protein 8
chr1_-_175192911 7.84 ENST00000444639.5
KIAA0040
chr7_+_100373458 7.80 ENST00000453419.5
ENST00000198536.7
ENST00000394000.6
ENST00000350573.2
paired immunoglobin like type 2 receptor alpha
chr7_+_99374722 7.78 ENST00000418347.6
ENST00000429246.6
ENST00000417330.6
ENST00000431816.6
ENST00000458033.6
ENST00000451682.5
ENST00000427217.6
ENST00000646101.2
actin related protein 2/3 complex subunit 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of SPI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
23.0 114.8 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
13.6 40.9 GO:0034769 basement membrane disassembly(GO:0034769)
10.9 10.9 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
10.0 40.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
9.5 19.0 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
8.2 40.9 GO:0002357 defense response to tumor cell(GO:0002357)
8.0 55.7 GO:0044027 hypermethylation of CpG island(GO:0044027)
7.8 62.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
7.0 21.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
6.5 19.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
6.1 30.5 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
6.0 18.0 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
4.9 24.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
4.8 4.8 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
4.8 14.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
4.6 46.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
4.6 18.2 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
4.2 42.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
4.2 25.3 GO:0071461 cellular response to redox state(GO:0071461)
4.1 12.4 GO:0061485 memory T cell proliferation(GO:0061485)
4.0 67.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
3.9 11.8 GO:0070662 mast cell proliferation(GO:0070662)
3.7 11.1 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876) positive regulation of translational initiation by iron(GO:0045994) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
3.6 21.9 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
3.5 21.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
3.4 17.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
3.2 12.9 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
3.2 9.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
2.9 11.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.9 2.9 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
2.9 2.9 GO:1903006 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
2.8 11.1 GO:0042631 cellular response to water deprivation(GO:0042631)
2.7 13.7 GO:0039650 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
2.7 10.7 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
2.7 5.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
2.6 7.9 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
2.3 7.0 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
2.3 13.9 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
2.3 95.6 GO:0045730 respiratory burst(GO:0045730)
2.3 9.1 GO:0021569 rhombomere 3 development(GO:0021569)
2.3 38.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
2.2 24.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
2.1 16.6 GO:0035696 monocyte extravasation(GO:0035696)
2.1 8.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
2.0 6.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
2.0 11.8 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
1.9 5.8 GO:0060876 semicircular canal formation(GO:0060876)
1.9 33.6 GO:0048290 isotype switching to IgA isotypes(GO:0048290)
1.8 16.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
1.8 10.7 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
1.7 3.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
1.7 6.9 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
1.6 4.7 GO:0070105 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.5 4.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.4 2.8 GO:1902463 protein localization to cell leading edge(GO:1902463)
1.4 4.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
1.4 7.0 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
1.4 37.5 GO:0035855 megakaryocyte development(GO:0035855)
1.4 32.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.3 5.3 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
1.3 6.7 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.3 6.6 GO:0007296 vitellogenesis(GO:0007296)
1.3 11.7 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
1.2 2.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.2 29.0 GO:0051014 actin filament severing(GO:0051014)
1.2 3.6 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
1.2 60.5 GO:0070207 protein homotrimerization(GO:0070207)
1.2 11.7 GO:0008063 Toll signaling pathway(GO:0008063)
1.2 3.5 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
1.1 5.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
1.1 17.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.1 1.1 GO:0060458 right lung development(GO:0060458)
1.1 6.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
1.1 9.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.1 2.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
1.1 8.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.0 4.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.0 6.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.0 11.2 GO:0002517 T cell tolerance induction(GO:0002517)
1.0 10.0 GO:0071317 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
1.0 6.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.0 39.4 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
1.0 4.9 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
1.0 19.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.0 4.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.9 5.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.9 36.8 GO:0097320 membrane tubulation(GO:0097320)
0.9 85.2 GO:0006968 cellular defense response(GO:0006968)
0.9 10.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.9 4.5 GO:0002384 hepatic immune response(GO:0002384)
0.9 8.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.9 16.8 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.9 5.3 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.9 4.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.8 4.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.8 17.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.8 5.8 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.8 9.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.8 4.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.8 63.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.8 2.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.8 19.9 GO:0042832 defense response to protozoan(GO:0042832)
0.8 4.7 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.8 8.6 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.8 13.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.8 6.2 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.8 9.4 GO:0002467 germinal center formation(GO:0002467)
0.8 18.6 GO:0030220 platelet formation(GO:0030220)
0.8 3.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.8 8.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.8 6.9 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.8 9.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.7 13.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.7 2.2 GO:0007518 myoblast fate determination(GO:0007518)
0.7 13.8 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.7 2.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.7 2.8 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.7 16.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.7 2.1 GO:1904826 regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.7 5.5 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.7 12.9 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.7 12.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.7 7.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.7 16.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.6 1.9 GO:1990637 response to prolactin(GO:1990637)
0.6 17.6 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6 8.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.6 1.9 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.6 3.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.6 45.8 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.6 9.0 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.6 3.6 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.6 5.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.6 7.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 3.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.6 1.8 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.6 5.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.6 4.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.6 1.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.5 24.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.5 13.2 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.5 10.9 GO:0038203 TORC2 signaling(GO:0038203)
0.5 6.5 GO:0006116 NADH oxidation(GO:0006116)
0.5 15.7 GO:0072678 T cell migration(GO:0072678)
0.5 38.8 GO:0042100 B cell proliferation(GO:0042100)
0.5 19.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.5 26.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.5 6.3 GO:0007144 female meiosis I(GO:0007144)
0.5 6.7 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.5 5.7 GO:0002347 response to tumor cell(GO:0002347)
0.5 2.6 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.5 4.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.5 2.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.5 3.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.5 10.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.5 2.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 2.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.5 5.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.5 8.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.5 21.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.5 4.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.5 2.7 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.5 5.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.4 2.7 GO:0045076 regulation of interleukin-2 biosynthetic process(GO:0045076)
0.4 10.6 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.4 1.3 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.4 6.0 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.4 4.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 3.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 10.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.4 2.8 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.4 1.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 9.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 19.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 1.9 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.4 3.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) positive regulation of protein monoubiquitination(GO:1902527)
0.4 11.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 2.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.4 3.8 GO:0070995 NADPH oxidation(GO:0070995)
0.4 2.2 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.4 1.5 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.4 12.1 GO:0043101 purine-containing compound salvage(GO:0043101)
0.4 8.4 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.4 2.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 71.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.4 4.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.4 6.8 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 1.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.4 4.3 GO:0090168 Golgi reassembly(GO:0090168)
0.4 0.7 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 5.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 11.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 0.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.3 3.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 19.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.3 2.0 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
0.3 10.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.3 2.9 GO:0060136 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.3 1.6 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572)
0.3 2.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.3 17.9 GO:0045576 mast cell activation(GO:0045576)
0.3 3.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 1.3 GO:0021553 olfactory nerve development(GO:0021553)
0.3 2.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.3 10.8 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.3 3.8 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.3 3.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 3.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 2.9 GO:0009826 unidimensional cell growth(GO:0009826)
0.3 1.7 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.3 6.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 9.4 GO:0006491 N-glycan processing(GO:0006491)
0.3 4.7 GO:0032462 regulation of protein homooligomerization(GO:0032462) positive regulation of protein homooligomerization(GO:0032464)
0.3 1.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 1.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.3 1.4 GO:0090166 Golgi disassembly(GO:0090166)
0.3 3.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.3 1.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 5.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.3 2.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.3 0.8 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 4.6 GO:0036065 fucosylation(GO:0036065)
0.3 1.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 4.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.3 5.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 2.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.2 2.5 GO:0090527 actin filament reorganization(GO:0090527)
0.2 147.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.2 1.5 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.2 3.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 2.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 1.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.7 GO:0036090 cleavage furrow ingression(GO:0036090)
0.2 1.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 2.7 GO:0060613 fat pad development(GO:0060613)
0.2 0.7 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 0.6 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 0.2 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 1.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 10.5 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.2 26.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 3.1 GO:0000012 single strand break repair(GO:0000012)
0.2 2.2 GO:0051665 membrane raft localization(GO:0051665)
0.2 0.4 GO:0001927 exocyst assembly(GO:0001927)
0.2 5.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 6.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2 1.7 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 0.6 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 1.3 GO:0007172 signal complex assembly(GO:0007172)
0.2 2.0 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 2.6 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.2 1.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 4.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 3.4 GO:0034205 beta-amyloid formation(GO:0034205)
0.2 0.4 GO:0002692 negative regulation of cellular extravasation(GO:0002692) regulation of leukocyte tethering or rolling(GO:1903236)
0.2 27.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 16.6 GO:1902017 regulation of cilium assembly(GO:1902017)
0.2 1.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2 1.4 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.2 18.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.2 1.5 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 6.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 1.8 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.2 3.0 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 3.6 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.2 1.0 GO:0010157 response to chlorate(GO:0010157)
0.2 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 1.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2 1.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 3.0 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.2 1.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 0.6 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.2 4.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 3.6 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 1.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 1.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.8 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.8 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 11.5 GO:0007602 phototransduction(GO:0007602)
0.1 3.7 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.3 GO:0097338 response to clozapine(GO:0097338)
0.1 2.4 GO:1902743 regulation of lamellipodium organization(GO:1902743)
0.1 7.2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 3.3 GO:0015671 oxygen transport(GO:0015671)
0.1 2.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 2.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 5.3 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 1.8 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 2.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 74.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 1.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 2.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.7 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 4.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 3.6 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.3 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.1 0.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.6 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.2 GO:0097178 ruffle assembly(GO:0097178)
0.1 2.3 GO:0044804 nucleophagy(GO:0044804)
0.1 1.7 GO:0021794 thalamus development(GO:0021794)
0.1 5.4 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 0.8 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 3.4 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 2.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 1.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 1.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.4 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 1.6 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 2.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 1.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 1.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 2.9 GO:0032402 melanosome transport(GO:0032402)
0.1 2.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 5.0 GO:0048678 response to axon injury(GO:0048678)
0.1 2.0 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 1.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 3.0 GO:0043087 regulation of GTPase activity(GO:0043087)
0.1 2.8 GO:0001824 blastocyst development(GO:0001824)
0.1 1.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 3.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.6 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 8.6 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.6 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 1.0 GO:0045116 protein neddylation(GO:0045116)
0.1 8.5 GO:0002576 platelet degranulation(GO:0002576)
0.1 3.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 2.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 2.8 GO:0010107 potassium ion import(GO:0010107)
0.0 1.8 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 1.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.9 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 1.2 GO:0036035 osteoclast development(GO:0036035)
0.0 1.0 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 1.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 4.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 2.6 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.7 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 1.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.2 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.7 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.9 GO:0032418 lysosome localization(GO:0032418)
0.0 0.8 GO:0043586 tongue development(GO:0043586)
0.0 1.3 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 1.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 1.4 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 1.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.7 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 1.4 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 3.4 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.7 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 1.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.6 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.1 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 1.9 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.1 GO:2000643 positive regulation of vacuolar transport(GO:1903337) positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 101.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
7.2 28.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
6.0 66.3 GO:0032010 phagolysosome(GO:0032010)
5.8 40.9 GO:0036021 endolysosome lumen(GO:0036021)
5.6 16.7 GO:0016590 ACF complex(GO:0016590)
5.5 27.5 GO:0019815 B cell receptor complex(GO:0019815)
5.2 51.8 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
5.2 15.5 GO:0036284 tubulobulbar complex(GO:0036284)
4.9 24.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
4.5 40.9 GO:0044194 cytolytic granule(GO:0044194)
3.1 18.5 GO:0036398 TCR signalosome(GO:0036398)
2.2 12.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.1 84.4 GO:0001891 phagocytic cup(GO:0001891)
2.1 16.4 GO:1990111 spermatoproteasome complex(GO:1990111)
2.0 12.1 GO:1902560 GMP reductase complex(GO:1902560)
2.0 11.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
1.8 21.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.7 40.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.6 4.9 GO:0042022 interleukin-12 receptor complex(GO:0042022)
1.5 29.0 GO:0032059 bleb(GO:0032059)
1.5 107.2 GO:0001772 immunological synapse(GO:0001772)
1.4 22.7 GO:0031209 SCAR complex(GO:0031209)
1.2 14.3 GO:0043020 NADPH oxidase complex(GO:0043020)
1.2 22.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.9 18.7 GO:0070938 contractile ring(GO:0070938)
0.9 6.0 GO:0042101 T cell receptor complex(GO:0042101)
0.8 4.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.8 6.8 GO:0005577 fibrinogen complex(GO:0005577)
0.7 4.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.7 4.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.7 2.8 GO:0071817 MMXD complex(GO:0071817)
0.7 3.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.7 4.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.7 303.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.7 8.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.7 2.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.6 13.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.6 7.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.6 3.0 GO:0071159 NF-kappaB complex(GO:0071159)
0.6 9.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.6 6.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.6 14.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.6 5.1 GO:0032009 early phagosome(GO:0032009)
0.6 62.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.6 1.7 GO:0016939 kinesin II complex(GO:0016939)
0.6 12.7 GO:0042588 zymogen granule(GO:0042588)
0.5 3.8 GO:1990031 pinceau fiber(GO:1990031)
0.5 42.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 17.0 GO:0042629 mast cell granule(GO:0042629)
0.5 1.9 GO:0032449 CBM complex(GO:0032449)
0.5 3.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.5 2.4 GO:0042643 actomyosin, actin portion(GO:0042643)
0.5 13.6 GO:0005916 fascia adherens(GO:0005916)
0.4 12.4 GO:0031932 TORC2 complex(GO:0031932)
0.4 3.7 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4 1.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.4 2.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.4 35.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.4 38.3 GO:0035580 specific granule lumen(GO:0035580)
0.4 3.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 2.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.4 4.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.4 4.2 GO:0001940 male pronucleus(GO:0001940)
0.3 2.6 GO:0016272 prefoldin complex(GO:0016272)
0.3 6.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 1.8 GO:0048179 activin receptor complex(GO:0048179)
0.3 5.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 2.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 7.7 GO:0031528 microvillus membrane(GO:0031528)
0.3 3.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 3.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 3.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 4.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 1.9 GO:1990037 Lewy body core(GO:1990037)
0.2 4.5 GO:0097433 dense body(GO:0097433)
0.2 6.9 GO:0042627 chylomicron(GO:0042627)
0.2 3.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 3.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 0.7 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.2 10.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 1.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 3.4 GO:0071141 SMAD protein complex(GO:0071141)
0.2 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 0.6 GO:0055087 Ski complex(GO:0055087)
0.2 1.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 83.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 2.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 0.7 GO:0034457 Mpp10 complex(GO:0034457)
0.2 3.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 2.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 2.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 84.8 GO:0000790 nuclear chromatin(GO:0000790)
0.2 0.8 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.4 GO:0097452 GAIT complex(GO:0097452)
0.2 4.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 1.0 GO:0032044 DSIF complex(GO:0032044)
0.2 69.8 GO:0034774 secretory granule lumen(GO:0034774)
0.2 1.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 1.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 1.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 11.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.4 GO:0008278 cohesin complex(GO:0008278)
0.1 2.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.9 GO:0002102 podosome(GO:0002102)
0.1 9.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.9 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 1.0 GO:0033270 paranode region of axon(GO:0033270)
0.1 13.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.3 GO:0042382 paraspeckles(GO:0042382)
0.1 3.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 3.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0031417 NatC complex(GO:0031417)
0.1 2.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 5.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 5.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 22.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 30.4 GO:0001726 ruffle(GO:0001726)
0.1 36.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 3.2 GO:0005776 autophagosome(GO:0005776)
0.1 0.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.6 GO:0010369 chromocenter(GO:0010369)
0.1 4.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 13.8 GO:0016605 PML body(GO:0016605)
0.1 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 17.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 2.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.3 GO:0016235 aggresome(GO:0016235)
0.1 1.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 6.3 GO:0034707 chloride channel complex(GO:0034707)
0.1 10.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 5.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.7 GO:0043596 nuclear replication fork(GO:0043596)
0.1 1.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 10.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.9 GO:0046930 pore complex(GO:0046930)
0.0 4.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 9.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 4.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 7.7 GO:0030027 lamellipodium(GO:0030027)
0.0 4.1 GO:0031252 cell leading edge(GO:0031252)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.4 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 5.7 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.1 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 16.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 14.4 GO:0097708 intracellular vesicle(GO:0097708)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 42.4 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
6.4 12.9 GO:0004917 interleukin-7 receptor activity(GO:0004917)
6.3 18.8 GO:0005174 CD40 receptor binding(GO:0005174)
5.7 40.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
4.7 66.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
4.7 51.8 GO:0030369 ICAM-3 receptor activity(GO:0030369)
4.0 55.7 GO:0051525 NFAT protein binding(GO:0051525)
3.9 65.9 GO:0042608 T cell receptor binding(GO:0042608)
3.2 9.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
3.1 25.1 GO:0043208 glycosphingolipid binding(GO:0043208)
2.9 5.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
2.7 62.4 GO:0005522 profilin binding(GO:0005522)
2.7 10.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
2.7 21.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
2.6 111.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.5 25.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.4 7.1 GO:0035375 zymogen binding(GO:0035375)
2.3 32.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
2.2 19.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
2.1 12.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
2.1 10.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
2.0 16.3 GO:0004974 leukotriene receptor activity(GO:0004974)
2.0 12.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
2.0 59.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
2.0 5.9 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.0 13.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.8 43.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.8 8.9 GO:0070051 fibrinogen binding(GO:0070051)
1.7 5.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.7 8.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.7 21.6 GO:0008420 CTD phosphatase activity(GO:0008420)
1.7 29.9 GO:0019864 IgG binding(GO:0019864)
1.6 4.9 GO:0016517 interleukin-12 receptor activity(GO:0016517)
1.6 4.7 GO:0004132 dCMP deaminase activity(GO:0004132)
1.5 4.5 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
1.4 5.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.4 10.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.3 11.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.3 46.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.2 4.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
1.1 13.6 GO:0033691 sialic acid binding(GO:0033691)
1.1 9.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.1 4.5 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
1.1 4.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
1.0 3.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
1.0 6.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.0 4.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.0 19.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.0 6.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.0 45.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.0 19.5 GO:0035325 Toll-like receptor binding(GO:0035325)
1.0 3.9 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
1.0 35.6 GO:0022829 wide pore channel activity(GO:0022829)
0.8 4.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.8 16.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.8 14.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.8 25.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.8 3.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.8 40.9 GO:0043236 laminin binding(GO:0043236)
0.8 9.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.8 31.5 GO:0017166 vinculin binding(GO:0017166)
0.8 16.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.7 9.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 2.2 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.7 3.6 GO:1990460 leptin receptor binding(GO:1990460)
0.7 20.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.7 5.6 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.7 2.8 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.7 8.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.6 2.6 GO:0001626 nociceptin receptor activity(GO:0001626)
0.6 1.9 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.6 30.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.6 25.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.6 34.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.6 13.2 GO:0051400 BH domain binding(GO:0051400)
0.6 2.9 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.6 1.7 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.5 4.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 3.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.5 4.9 GO:1990405 protein antigen binding(GO:1990405)
0.5 5.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 16.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 24.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5 3.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.5 40.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5 6.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.5 5.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.5 1.5 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.5 6.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 4.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.5 6.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 47.9 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.5 3.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.5 4.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.5 65.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.4 228.4 GO:0005096 GTPase activator activity(GO:0005096)
0.4 2.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.4 12.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 3.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 1.3 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.4 2.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 1.7 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.4 7.2 GO:0045159 myosin II binding(GO:0045159)
0.4 3.8 GO:0043426 MRF binding(GO:0043426)
0.4 3.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 10.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 11.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.4 2.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 2.0 GO:0098808 mRNA cap binding(GO:0098808)
0.4 3.4 GO:0035500 MH2 domain binding(GO:0035500)
0.4 24.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.4 4.6 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 5.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 8.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 10.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 2.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.3 2.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.3 2.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 10.4 GO:0043274 phospholipase binding(GO:0043274)
0.3 4.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 2.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 6.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 5.8 GO:0003680 AT DNA binding(GO:0003680)
0.3 3.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 1.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 12.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 2.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.6 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.3 9.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 2.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3 1.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.3 11.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 2.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 0.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2 3.6 GO:0015925 galactosidase activity(GO:0015925)
0.2 3.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.2 11.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 5.5 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.2 1.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.2 2.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 1.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 12.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 6.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 2.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 2.9 GO:0008097 5S rRNA binding(GO:0008097)
0.2 2.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 4.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 4.1 GO:0003678 DNA helicase activity(GO:0003678)
0.2 6.0 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 4.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 9.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 2.4 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.2 7.1 GO:0042169 SH2 domain binding(GO:0042169)
0.2 5.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 12.0 GO:0005080 protein kinase C binding(GO:0005080)
0.2 2.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 0.5 GO:0019808 polyamine binding(GO:0019808)
0.2 7.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 1.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 5.3 GO:0031489 myosin V binding(GO:0031489)
0.2 2.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 2.7 GO:0050700 CARD domain binding(GO:0050700)
0.2 23.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 0.6 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.2 4.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 14.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 7.0 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.4 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 1.2 GO:0004771 sterol esterase activity(GO:0004771)
0.1 3.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.0 GO:0019003 GDP binding(GO:0019003)
0.1 2.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.9 GO:0004966 galanin receptor activity(GO:0004966)
0.1 4.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.0 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 0.7 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 58.2 GO:0003924 GTPase activity(GO:0003924)
0.1 3.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 2.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 5.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 2.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 6.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 3.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 2.0 GO:0035198 miRNA binding(GO:0035198)
0.1 9.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 4.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 4.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 7.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 16.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 3.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.9 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 6.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 6.0 GO:0019843 rRNA binding(GO:0019843)
0.1 0.6 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 1.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 3.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 4.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.1 2.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 2.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 4.9 GO:0050681 androgen receptor binding(GO:0050681)
0.1 50.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 4.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 2.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.1 0.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 5.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 21.1 GO:0051020 GTPase binding(GO:0051020)
0.1 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 10.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 2.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 4.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 6.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 2.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 1.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 5.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.9 GO:0019209 kinase activator activity(GO:0019209)
0.0 1.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 2.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.7 GO:0032451 demethylase activity(GO:0032451)
0.0 1.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 379.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
1.6 66.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.5 61.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.3 55.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.2 79.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.2 34.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.0 68.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.0 36.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.0 17.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.9 66.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.9 97.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.8 70.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.7 28.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.7 31.1 PID BCR 5PATHWAY BCR signaling pathway
0.6 85.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.6 18.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6 12.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.5 15.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.5 4.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.4 47.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 6.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.4 15.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 1.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.3 12.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 7.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 9.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.3 7.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 10.3 ST GAQ PATHWAY G alpha q Pathway
0.3 5.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.3 23.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 15.0 PID ENDOTHELIN PATHWAY Endothelins
0.3 10.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.3 10.1 PID CONE PATHWAY Visual signal transduction: Cones
0.3 34.7 PID CMYB PATHWAY C-MYB transcription factor network
0.3 13.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.3 2.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 5.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 8.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 3.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 37.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 6.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 5.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 1.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 5.4 PID CD40 PATHWAY CD40/CD40L signaling
0.2 7.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 1.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.2 3.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 6.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 8.2 PID ARF6 PATHWAY Arf6 signaling events
0.1 8.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 4.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 8.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 1.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 4.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 5.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 3.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 27.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 4.4 PID P53 REGULATION PATHWAY p53 pathway
0.1 7.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 11.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 10.9 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 237.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
3.7 40.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
2.8 2.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
2.4 78.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
1.9 13.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
1.8 1.8 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
1.4 156.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.4 77.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.4 66.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
1.4 20.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.4 104.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
1.4 27.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.1 8.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
1.1 21.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.0 3.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
1.0 15.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.0 60.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.9 11.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.8 3.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.8 8.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.8 12.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.8 20.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.7 23.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.7 10.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.7 21.8 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.7 12.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 16.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 8.4 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.6 1.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.6 10.5 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.5 10.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.5 145.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.5 15.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.5 6.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.5 28.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.4 8.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 12.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 11.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 20.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.4 11.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.4 5.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 6.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.4 32.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 5.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.4 14.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 17.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 4.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 7.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 8.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 4.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 13.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 46.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.3 7.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 12.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 16.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.3 3.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 4.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 25.5 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.2 1.9 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.2 9.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 2.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 2.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 9.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2 16.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 8.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.9 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 11.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 3.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 4.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 14.8 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 1.3 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.1 2.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.7 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 6.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 7.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 5.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 14.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 2.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 5.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.5 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.9 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions