Illumina Body Map 2 (GSE30611)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
SPI1 | hg38_v1_chr11_-_47378527_47378555 | 0.90 | 4.3e-12 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 147.2 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
23.0 | 114.8 | GO:2000471 | regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473) |
2.3 | 95.6 | GO:0045730 | respiratory burst(GO:0045730) |
0.9 | 85.2 | GO:0006968 | cellular defense response(GO:0006968) |
0.1 | 74.9 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
0.4 | 71.1 | GO:0038094 | Fc-gamma receptor signaling pathway(GO:0038094) |
4.0 | 67.5 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
0.8 | 63.7 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
7.8 | 62.7 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
1.2 | 60.5 | GO:0070207 | protein homotrimerization(GO:0070207) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 303.8 | GO:0009897 | external side of plasma membrane(GO:0009897) |
1.5 | 107.2 | GO:0001772 | immunological synapse(GO:0001772) |
8.4 | 101.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.2 | 84.8 | GO:0000790 | nuclear chromatin(GO:0000790) |
2.1 | 84.4 | GO:0001891 | phagocytic cup(GO:0001891) |
0.2 | 83.5 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.2 | 69.8 | GO:0034774 | secretory granule lumen(GO:0034774) |
6.0 | 66.3 | GO:0032010 | phagolysosome(GO:0032010) |
0.6 | 62.5 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
5.2 | 51.8 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 228.4 | GO:0005096 | GTPase activator activity(GO:0005096) |
2.6 | 111.9 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
4.7 | 66.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
3.9 | 65.9 | GO:0042608 | T cell receptor binding(GO:0042608) |
0.5 | 65.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
2.7 | 62.4 | GO:0005522 | profilin binding(GO:0005522) |
2.0 | 59.6 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.1 | 58.2 | GO:0003924 | GTPase activity(GO:0003924) |
4.0 | 55.7 | GO:0051525 | NFAT protein binding(GO:0051525) |
4.7 | 51.8 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.2 | 379.9 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
0.9 | 97.8 | PID RAC1 PATHWAY | RAC1 signaling pathway |
0.6 | 85.6 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
1.2 | 79.8 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.8 | 70.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
1.0 | 68.7 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
1.6 | 66.9 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
0.9 | 66.6 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
1.5 | 61.9 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
1.3 | 55.8 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
8.2 | 237.2 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
1.4 | 156.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.5 | 145.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
1.4 | 104.5 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
2.4 | 78.0 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
1.4 | 77.9 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
1.4 | 66.6 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
1.0 | 60.6 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
0.3 | 46.8 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
3.7 | 40.9 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |