Illumina Body Map 2 (GSE30611)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
SPIC | hg38_v1_chr12_+_101475319_101475340 | 0.33 | 6.6e-02 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 78.6 | GO:0038094 | Fc-gamma receptor signaling pathway(GO:0038094) |
1.3 | 57.1 | GO:0045730 | respiratory burst(GO:0045730) |
0.1 | 53.4 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
0.4 | 45.6 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
0.3 | 41.0 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
4.6 | 36.6 | GO:0002774 | Fc receptor mediated inhibitory signaling pathway(GO:0002774) |
0.1 | 35.8 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
10.6 | 31.7 | GO:0034125 | negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) |
3.1 | 31.4 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
1.1 | 28.9 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 127.7 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.3 | 118.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 100.9 | GO:0016021 | integral component of membrane(GO:0016021) |
0.3 | 48.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.4 | 47.0 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
3.8 | 41.6 | GO:0032010 | phagolysosome(GO:0032010) |
0.8 | 31.4 | GO:0001891 | phagocytic cup(GO:0001891) |
1.9 | 30.1 | GO:0031209 | SCAR complex(GO:0031209) |
0.3 | 26.4 | GO:0035577 | azurophil granule membrane(GO:0035577) |
0.2 | 24.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 112.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.2 | 60.3 | GO:0003823 | antigen binding(GO:0003823) |
0.6 | 49.3 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
3.0 | 41.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
4.6 | 36.6 | GO:0032396 | inhibitory MHC class I receptor activity(GO:0032396) |
0.1 | 33.3 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 31.8 | GO:0060089 | receptor activity(GO:0004872) molecular transducer activity(GO:0060089) |
1.7 | 30.9 | GO:0019864 | IgG binding(GO:0019864) |
0.0 | 30.8 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
1.3 | 30.4 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 84.0 | PID BCR 5PATHWAY | BCR signaling pathway |
0.9 | 60.3 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.5 | 58.5 | PID RAC1 PATHWAY | RAC1 signaling pathway |
0.2 | 31.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
0.4 | 25.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
0.1 | 23.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
0.6 | 21.9 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.6 | 19.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.3 | 19.3 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
0.4 | 17.9 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 104.0 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.2 | 74.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
1.3 | 54.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.3 | 46.0 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.7 | 39.3 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.2 | 36.0 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
0.6 | 33.7 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
0.5 | 30.2 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
0.3 | 26.5 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.4 | 24.5 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |