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Illumina Body Map 2 (GSE30611)

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Results for SRY

Z-value: 0.97

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Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
SRY
ENSG00000184895.8 sex determining region Y

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg38_v1_chrY_-_2787676_27876870.048.4e-01Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_39467598 3.79 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
MOBP
myelin associated oligodendrocyte basic protein
chr10_+_11164961 3.72 ENST00000399850.7
ENST00000417956.6
CELF2
CUGBP Elav-like family member 2
chr21_-_31558977 2.74 ENST00000286827.7
ENST00000541036.5
TIAM1
TIAM Rac1 associated GEF 1
chr3_+_39467672 2.74 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
MOBP
myelin associated oligodendrocyte basic protein
chrX_+_108045050 2.69 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr7_+_28412511 2.58 ENST00000357727.7
CREB5
cAMP responsive element binding protein 5
chr11_+_112961247 2.43 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
NCAM1
neural cell adhesion molecule 1
chrX_+_108044967 2.32 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr11_-_118225002 2.31 ENST00000356289.10
ENST00000526620.5
JAML
junction adhesion molecule like
chr14_-_59630582 2.27 ENST00000395090.5
RTN1
reticulon 1
chr21_-_31160904 2.22 ENST00000636887.1
TIAM1
TIAM Rac1 associated GEF 1
chr5_-_147056010 2.14 ENST00000394414.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr1_-_39901996 2.08 ENST00000397332.2
MYCL
MYCL proto-oncogene, bHLH transcription factor
chr1_-_39901861 2.05 ENST00000372816.3
ENST00000372815.1
MYCL
MYCL proto-oncogene, bHLH transcription factor
chr10_+_97319250 2.05 ENST00000371021.5
FRAT1
FRAT regulator of WNT signaling pathway 1
chr10_+_11165088 2.05 ENST00000608830.5
CELF2
CUGBP Elav-like family member 2
chr5_-_147782681 2.04 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
JAKMIP2
janus kinase and microtubule interacting protein 2
chr5_-_147055968 2.03 ENST00000336640.10
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr9_-_89436476 2.00 ENST00000420681.6
SEMA4D
semaphorin 4D
chr13_-_99258366 1.99 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18
chr22_+_19723525 1.94 ENST00000366425.4
GP1BB
glycoprotein Ib platelet subunit beta
chrX_-_19670983 1.92 ENST00000379716.5
SH3KBP1
SH3 domain containing kinase binding protein 1
chr5_-_111756245 1.88 ENST00000447165.6
NREP
neuronal regeneration related protein
chr12_+_94148553 1.83 ENST00000258526.9
PLXNC1
plexin C1
chr3_-_71304741 1.80 ENST00000484350.5
FOXP1
forkhead box P1
chr7_+_106865263 1.71 ENST00000440650.6
ENST00000496166.6
ENST00000473541.5
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr5_-_150086427 1.70 ENST00000543093.1
CSF1R
colony stimulating factor 1 receptor
chr10_-_97334698 1.69 ENST00000371019.4
FRAT2
FRAT regulator of WNT signaling pathway 2
chr14_-_89494051 1.67 ENST00000555034.5
ENST00000553904.1
FOXN3
forkhead box N3
chr13_-_46142834 1.66 ENST00000674665.1
LCP1
lymphocyte cytosolic protein 1
chr12_-_121536069 1.63 ENST00000538379.5
ENST00000541318.1
ENST00000541511.1
KDM2B
lysine demethylase 2B
chr9_-_89436439 1.62 ENST00000418828.1
SEMA4D
semaphorin 4D
chr7_+_80638633 1.57 ENST00000447544.7
ENST00000482059.6
CD36
CD36 molecule
chr1_+_84164962 1.56 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr5_-_147081428 1.56 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr2_-_60546162 1.55 ENST00000489183.1
ENST00000647469.1
ENST00000642180.1
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr1_+_40374648 1.55 ENST00000372708.5
SMAP2
small ArfGAP2
chr11_-_134412234 1.50 ENST00000312527.9
B3GAT1
beta-1,3-glucuronyltransferase 1
chr5_-_150086511 1.47 ENST00000675795.1
CSF1R
colony stimulating factor 1 receptor
chr17_-_64390592 1.45 ENST00000563523.5
PECAM1
platelet and endothelial cell adhesion molecule 1
chr1_+_84164370 1.43 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr1_+_84164891 1.38 ENST00000413538.5
ENST00000417530.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr5_-_147081462 1.37 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr10_+_69088096 1.37 ENST00000242465.4
SRGN
serglycin
chr11_-_46826842 1.34 ENST00000526496.1
CKAP5
cytoskeleton associated protein 5
chr10_+_113125536 1.33 ENST00000349937.7
TCF7L2
transcription factor 7 like 2
chr15_-_34318761 1.33 ENST00000290209.9
SLC12A6
solute carrier family 12 member 6
chr7_-_78771058 1.30 ENST00000628781.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_108166750 1.30 ENST00000515500.5
LEF1
lymphoid enhancer binding factor 1
chr22_+_39901075 1.29 ENST00000344138.9
GRAP2
GRB2 related adaptor protein 2
chr10_-_14571969 1.28 ENST00000488576.5
ENST00000472095.5
FAM107B
family with sequence similarity 107 member B
chr5_+_138337511 1.28 ENST00000434981.6
FAM53C
family with sequence similarity 53 member C
chr7_+_106865474 1.27 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr10_+_11165475 1.27 ENST00000609692.5
ENST00000354897.3
CELF2
CUGBP Elav-like family member 2
chr3_+_115623502 1.27 ENST00000305124.11
ENST00000393780.3
GAP43
growth associated protein 43
chr16_+_53435612 1.27 ENST00000544405.6
RBL2
RB transcriptional corepressor like 2
chr13_-_74133892 1.26 ENST00000377669.7
KLF12
Kruppel like factor 12
chr14_+_22281097 1.24 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr20_-_54028692 1.22 ENST00000448484.5
BCAS1
brain enriched myelin associated protein 1
chr5_+_126777112 1.22 ENST00000261366.10
ENST00000492190.5
ENST00000395354.1
LMNB1
lamin B1
chr4_-_108166715 1.19 ENST00000510624.5
LEF1
lymphoid enhancer binding factor 1
chr10_-_14572313 1.18 ENST00000479731.5
ENST00000468492.5
FAM107B
family with sequence similarity 107 member B
chr21_-_17819386 1.17 ENST00000400559.7
ENST00000400558.7
C21orf91
chromosome 21 open reading frame 91
chr1_+_84164669 1.17 ENST00000450730.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr1_+_50108856 1.17 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAVL4
ELAV like RNA binding protein 4
chr7_-_78771108 1.17 ENST00000626691.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_74002685 1.16 ENST00000305799.8
TET3
tet methylcytosine dioxygenase 3
chr5_+_134524305 1.15 ENST00000431355.2
JADE2
jade family PHD finger 2
chr21_-_17819343 1.13 ENST00000284881.9
C21orf91
chromosome 21 open reading frame 91
chr2_-_144516397 1.12 ENST00000638128.1
ZEB2
zinc finger E-box binding homeobox 2
chr10_-_14572087 1.12 ENST00000482277.5
ENST00000378462.5
FAM107B
family with sequence similarity 107 member B
chr11_+_112961402 1.11 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
NCAM1
neural cell adhesion molecule 1
chr12_-_75209814 1.09 ENST00000549446.6
KCNC2
potassium voltage-gated channel subfamily C member 2
chr11_+_128694052 1.09 ENST00000527786.7
ENST00000534087.3
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr10_-_14572123 1.08 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
FAM107B
family with sequence similarity 107 member B
chr11_+_128693887 1.06 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_35807974 1.05 ENST00000373210.4
AGO4
argonaute RISC component 4
chr12_-_76423256 1.05 ENST00000546946.5
OSBPL8
oxysterol binding protein like 8
chr1_+_226063466 1.04 ENST00000666609.1
ENST00000661429.1
H3-3A
H3.3 histone A
chr17_+_78041043 1.03 ENST00000588549.1
TNRC6C
trinucleotide repeat containing adaptor 6C
chr11_-_46119787 1.02 ENST00000529782.5
ENST00000532010.5
ENST00000525438.5
ENST00000533757.5
ENST00000527782.5
PHF21A
PHD finger protein 21A
chr10_+_110207587 1.00 ENST00000332674.9
ENST00000453116.5
MXI1
MAX interactor 1, dimerization protein
chr1_+_50106265 1.00 ENST00000357083.8
ELAVL4
ELAV like RNA binding protein 4
chr2_-_144516154 0.99 ENST00000637304.1
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_138338256 0.98 ENST00000513056.5
ENST00000239906.10
ENST00000511276.1
FAM53C
family with sequence similarity 53 member C
chr8_+_66493556 0.97 ENST00000305454.8
ENST00000522977.5
ENST00000480005.1
VXN
vexin
chr1_+_84164684 0.96 ENST00000370680.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr12_-_389249 0.95 ENST00000535014.5
ENST00000543507.1
ENST00000544760.1
ENST00000399788.7
KDM5A
lysine demethylase 5A
chr12_-_75209701 0.93 ENST00000350228.6
ENST00000298972.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr7_+_80638510 0.92 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36
CD36 molecule
chr2_-_2331225 0.91 ENST00000648627.1
ENST00000649663.1
ENST00000650560.1
ENST00000428368.7
ENST00000648316.1
ENST00000648665.1
ENST00000649313.1
ENST00000399161.7
ENST00000647738.2
MYT1L
myelin transcription factor 1 like
chr5_-_147782518 0.91 ENST00000507386.5
JAKMIP2
janus kinase and microtubule interacting protein 2
chr5_+_179732811 0.91 ENST00000292599.4
MAML1
mastermind like transcriptional coactivator 1
chr7_-_78770859 0.91 ENST00000636717.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_66493514 0.90 ENST00000521495.5
VXN
vexin
chr2_-_151289871 0.88 ENST00000414946.1
NMI
N-myc and STAT interactor
chr2_+_86441341 0.88 ENST00000312912.10
ENST00000409064.5
KDM3A
lysine demethylase 3A
chr11_+_36296281 0.87 ENST00000530639.6
PRR5L
proline rich 5 like
chr8_+_21919731 0.86 ENST00000521303.5
XPO7
exportin 7
chr4_-_184474037 0.85 ENST00000510814.5
ENST00000507523.5
ENST00000506230.5
IRF2
interferon regulatory factor 2
chr1_+_50105666 0.84 ENST00000651347.1
ELAVL4
ELAV like RNA binding protein 4
chr12_+_389334 0.83 ENST00000540180.5
ENST00000422000.5
ENST00000535052.5
CCDC77
coiled-coil domain containing 77
chr1_+_66332004 0.82 ENST00000371045.9
ENST00000531025.5
ENST00000526197.5
PDE4B
phosphodiesterase 4B
chr12_+_59664677 0.81 ENST00000548610.5
SLC16A7
solute carrier family 16 member 7
chr12_-_75209422 0.80 ENST00000393288.2
ENST00000540018.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr11_+_22338333 0.79 ENST00000263160.4
SLC17A6
solute carrier family 17 member 6
chr17_-_59151794 0.79 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr8_-_132059378 0.79 ENST00000254627.4
OC90
otoconin 90
chr20_-_44521989 0.79 ENST00000342374.5
ENST00000255175.5
SERINC3
serine incorporator 3
chr7_+_30145789 0.78 ENST00000324489.5
MTURN
maturin, neural progenitor differentiation regulator homolog
chr5_-_88824266 0.78 ENST00000509373.1
ENST00000636541.1
MEF2C
myocyte enhancer factor 2C
chr1_-_156248084 0.78 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
PAQR6
progestin and adipoQ receptor family member 6
chr15_-_70097874 0.78 ENST00000557997.5
ENST00000317509.12
ENST00000451782.7
ENST00000627388.2
TLE3
TLE family member 3, transcriptional corepressor
chr7_+_131285041 0.77 ENST00000429546.5
MKLN1
muskelin 1
chr14_-_22819721 0.77 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
SLC7A7
solute carrier family 7 member 7
chr7_+_143288215 0.77 ENST00000619992.4
ENST00000310447.10
CASP2
caspase 2
chr7_+_143288364 0.76 ENST00000392925.6
CASP2
caspase 2
chr2_+_190408324 0.76 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
MFSD6
major facilitator superfamily domain containing 6
chr10_+_58334998 0.76 ENST00000373910.9
UBE2D1
ubiquitin conjugating enzyme E2 D1
chr14_-_89417148 0.76 ENST00000557258.6
FOXN3
forkhead box N3
chr16_-_15643024 0.74 ENST00000540441.6
MARF1
meiosis regulator and mRNA stability factor 1
chr11_-_119729158 0.74 ENST00000264025.8
NECTIN1
nectin cell adhesion molecule 1
chr17_-_42276341 0.74 ENST00000293328.8
STAT5B
signal transducer and activator of transcription 5B
chr1_-_156248013 0.73 ENST00000368270.2
PAQR6
progestin and adipoQ receptor family member 6
chr12_-_49110666 0.73 ENST00000547675.5
LMBR1L
limb development membrane protein 1 like
chr1_+_32651485 0.72 ENST00000490500.5
ENST00000445722.2
RBBP4
RB binding protein 4, chromatin remodeling factor
chr3_-_136194456 0.71 ENST00000434835.2
MSL2
MSL complex subunit 2
chr20_-_53995929 0.71 ENST00000422805.1
BCAS1
brain enriched myelin associated protein 1
chr4_+_169660062 0.71 ENST00000507875.5
ENST00000613795.4
CLCN3
chloride voltage-gated channel 3
chr1_-_156248038 0.71 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
PAQR6
progestin and adipoQ receptor family member 6
chr10_+_58334976 0.71 ENST00000615793.1
UBE2D1
ubiquitin conjugating enzyme E2 D1
chr6_-_42451261 0.71 ENST00000372917.8
ENST00000340840.6
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr6_+_83853576 0.71 ENST00000369687.2
RIPPLY2
ripply transcriptional repressor 2
chr2_-_2331336 0.70 ENST00000648933.1
ENST00000644820.1
MYT1L
myelin transcription factor 1 like
chr11_+_112961480 0.69 ENST00000621850.4
NCAM1
neural cell adhesion molecule 1
chr17_-_39607876 0.68 ENST00000302584.5
NEUROD2
neuronal differentiation 2
chr9_-_127980976 0.67 ENST00000373095.6
FAM102A
family with sequence similarity 102 member A
chr11_-_13440243 0.67 ENST00000530907.5
BTBD10
BTB domain containing 10
chr1_+_87328860 0.67 ENST00000370544.10
LMO4
LIM domain only 4
chr15_+_90001300 0.66 ENST00000268154.9
ZNF710
zinc finger protein 710
chr14_-_56805648 0.66 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
OTX2
orthodenticle homeobox 2
chr2_-_191847068 0.65 ENST00000304141.5
CAVIN2
caveolae associated protein 2
chr5_-_88824334 0.64 ENST00000506716.5
MEF2C
myocyte enhancer factor 2C
chr14_-_55411817 0.64 ENST00000247178.6
ATG14
autophagy related 14
chr3_-_33659097 0.63 ENST00000461133.8
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr5_-_11589019 0.63 ENST00000511377.5
CTNND2
catenin delta 2
chr8_+_78591222 0.62 ENST00000518467.1
PKIA
cAMP-dependent protein kinase inhibitor alpha
chr4_+_118034480 0.61 ENST00000296499.6
NDST3
N-deacetylase and N-sulfotransferase 3
chr2_-_165203870 0.61 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr15_+_76336755 0.59 ENST00000290759.9
ISL2
ISL LIM homeobox 2
chrX_-_111412162 0.58 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
DCX
doublecortin
chr11_+_67240047 0.58 ENST00000530342.2
KDM2A
lysine demethylase 2A
chr1_-_107688492 0.58 ENST00000415432.6
VAV3
vav guanine nucleotide exchange factor 3
chr5_+_163505564 0.58 ENST00000421814.6
ENST00000518095.5
ENST00000321757.11
MAT2B
methionine adenosyltransferase 2B
chr12_+_389378 0.57 ENST00000543504.5
CCDC77
coiled-coil domain containing 77
chr20_+_18145083 0.57 ENST00000489634.2
KAT14
lysine acetyltransferase 14
chr5_-_180803830 0.57 ENST00000427865.2
ENST00000514283.1
MGAT1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chrX_+_28587411 0.57 ENST00000378993.6
IL1RAPL1
interleukin 1 receptor accessory protein like 1
chr1_+_147902789 0.56 ENST00000369235.2
GJA8
gap junction protein alpha 8
chr12_+_50085325 0.56 ENST00000551966.5
ENST00000550477.5
ENST00000394963.9
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr16_+_30395400 0.56 ENST00000320159.2
ENST00000613509.2
ZNF48
zinc finger protein 48
chr1_+_99850485 0.54 ENST00000370165.7
ENST00000370163.7
ENST00000294724.8
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr11_-_73141275 0.54 ENST00000422375.1
FCHSD2
FCH and double SH3 domains 2
chr1_-_193186599 0.53 ENST00000367434.5
B3GALT2
beta-1,3-galactosyltransferase 2
chr2_+_86720282 0.53 ENST00000283632.5
RMND5A
required for meiotic nuclear division 5 homolog A
chrX_+_78747705 0.53 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
LPAR4
lysophosphatidic acid receptor 4
chr19_+_1942454 0.53 ENST00000591752.5
CSNK1G2
casein kinase 1 gamma 2
chr5_-_41794547 0.52 ENST00000510634.5
OXCT1
3-oxoacid CoA-transferase 1
chr14_-_23435652 0.52 ENST00000355349.4
MYH7
myosin heavy chain 7
chr6_-_31684040 0.52 ENST00000375863.7
LY6G5C
lymphocyte antigen 6 family member G5C
chr15_-_55270249 0.51 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr10_-_32378720 0.51 ENST00000375110.6
EPC1
enhancer of polycomb homolog 1
chr3_-_33659441 0.51 ENST00000650653.1
ENST00000480013.6
CLASP2
cytoplasmic linker associated protein 2
chr19_+_10602436 0.51 ENST00000590382.5
ENST00000407327.8
SLC44A2
solute carrier family 44 member 2
chr12_+_11649666 0.51 ENST00000396373.9
ETV6
ETS variant transcription factor 6
chr6_-_116545658 0.50 ENST00000368602.4
TRAPPC3L
trafficking protein particle complex 3 like
chr16_-_69356306 0.50 ENST00000563634.1
ENSG00000260371.1
novel protein
chr14_-_52552493 0.50 ENST00000281741.9
ENST00000557374.1
TXNDC16
thioredoxin domain containing 16
chr17_+_39653080 0.50 ENST00000443521.1
STARD3
StAR related lipid transfer domain containing 3
chr16_-_68448491 0.50 ENST00000561749.1
ENST00000219334.10
SMPD3
sphingomyelin phosphodiesterase 3
chr4_-_112516176 0.49 ENST00000313341.4
NEUROG2
neurogenin 2
chr8_+_24294107 0.49 ENST00000437154.6
ADAM28
ADAM metallopeptidase domain 28
chrX_-_24672654 0.49 ENST00000379145.5
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr2_-_207165923 0.48 ENST00000309446.11
KLF7
Kruppel like factor 7
chr3_-_71493500 0.48 ENST00000648380.1
ENST00000650295.1
FOXP1
forkhead box P1
chr3_+_179148341 0.48 ENST00000263967.4
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr18_+_75210789 0.47 ENST00000580243.3
TSHZ1
teashirt zinc finger homeobox 1
chr14_+_58427686 0.47 ENST00000650904.1
ENST00000652326.2
ENST00000554463.5
ENST00000555833.5
KIAA0586
KIAA0586
chr1_+_25338294 0.47 ENST00000374358.5
TMEM50A
transmembrane protein 50A
chr9_-_95509241 0.46 ENST00000331920.11
PTCH1
patched 1
chr11_+_131911396 0.46 ENST00000425719.6
ENST00000374784.5
NTM
neurotrimin
chr2_-_159616442 0.46 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
BAZ2B
bromodomain adjacent to zinc finger domain 2B
chr16_+_6019585 0.46 ENST00000547372.5
RBFOX1
RNA binding fox-1 homolog 1
chr17_-_64390852 0.46 ENST00000563924.6
PECAM1
platelet and endothelial cell adhesion molecule 1
chr11_-_82997394 0.45 ENST00000525117.5
ENST00000532548.5
RAB30
RAB30, member RAS oncogene family
chrX_+_100584928 0.45 ENST00000373031.5
TNMD
tenomodulin
chr5_-_138338325 0.45 ENST00000510119.1
ENST00000513970.5
CDC25C
cell division cycle 25C
chr8_-_115661667 0.44 ENST00000395713.6
TRPS1
transcriptional repressor GATA binding 1
chr3_-_183400538 0.44 ENST00000640043.1
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr8_+_24294044 0.44 ENST00000265769.9
ADAM28
ADAM metallopeptidase domain 28

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:1900149 positive regulation of Schwann cell migration(GO:1900149) regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.7 2.8 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.7 2.0 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.7 6.5 GO:0097338 response to clozapine(GO:0097338)
0.6 3.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.5 4.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.5 3.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.5 1.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.4 6.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 1.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.4 2.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 1.9 GO:0072011 glomerular endothelium development(GO:0072011)
0.3 1.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 3.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.3 1.6 GO:2000173 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.3 2.3 GO:0035696 monocyte extravasation(GO:0035696)
0.3 7.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.9 GO:0060922 atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.2 0.9 GO:0045355 negative regulation of interferon-alpha biosynthetic process(GO:0045355) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.2 0.9 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.2 0.8 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 1.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 2.5 GO:0072564 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 3.6 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.2 5.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 0.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.8 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.2 2.1 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.0 GO:0034721 negative regulation of histone deacetylation(GO:0031064) histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.0 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.5 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 1.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.6 GO:0016240 autophagosome docking(GO:0016240)
0.1 2.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.7 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1 0.9 GO:0060023 soft palate development(GO:0060023)
0.1 7.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.3 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.3 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.3 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.8 GO:0009597 detection of virus(GO:0009597)
0.1 1.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 3.5 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.8 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 1.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.5 GO:0010157 response to chlorate(GO:0010157)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 2.1 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.0 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 2.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 1.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 1.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 1.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.9 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.8 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 1.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.7 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.6 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.7 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.3 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.6 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.7 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.5 GO:0015871 choline transport(GO:0015871)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 5.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 1.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.4 GO:0001711 endodermal cell fate commitment(GO:0001711) histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.8 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0071043 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) CUT metabolic process(GO:0071043)
0.0 0.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.8 GO:0072431 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0 0.7 GO:0007143 female meiotic division(GO:0007143)
0.0 0.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.7 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.5 GO:0008038 neuron recognition(GO:0008038)
0.0 1.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.6 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.4 3.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 6.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.9 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 2.0 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 3.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 3.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.5 GO:0034657 GID complex(GO:0034657)
0.1 7.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.2 GO:0005638 lamin filament(GO:0005638)
0.1 1.2 GO:0001940 male pronucleus(GO:0001940)
0.1 1.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 4.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 2.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.2 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.1 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.8 GO:0030673 axolemma(GO:0030673)
0.0 1.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.9 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 6.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.0 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.3 6.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 3.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 6.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 3.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 2.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.8 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 1.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 0.5 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.2 2.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 3.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 6.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 7.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.5 GO:0035198 miRNA binding(GO:0035198)
0.1 2.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.6 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 3.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 7.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0046790 virion binding(GO:0046790)
0.0 0.8 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 2.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 3.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 3.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 1.0 GO:0032947 protein complex scaffold(GO:0032947)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 7.6 PID IL3 PATHWAY IL3-mediated signaling events
0.1 7.7 PID ATR PATHWAY ATR signaling pathway
0.1 3.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 3.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 4.0 PID FGF PATHWAY FGF signaling pathway
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 4.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 3.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 3.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 4.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 6.9 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 2.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 2.5 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis