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Illumina Body Map 2 (GSE30611)

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Results for STAT1_STAT3_BCL6

Z-value: 1.63

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
ENSG00000115415.20 signal transducer and activator of transcription 1
ENSG00000168610.16 signal transducer and activator of transcription 3
ENSG00000113916.18 BCL6 transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT1hg38_v1_chr2_-_191013955_191014112-0.468.0e-03Click!
STAT3hg38_v1_chr17_-_42388360_423884630.281.1e-01Click!
BCL6hg38_v1_chr3_-_187737943_187737954-0.212.5e-01Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_154590735 9.37 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr17_-_78360066 8.29 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chr1_-_230714112 8.28 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
angiotensinogen
chr3_-_149221811 7.12 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr3_-_93973833 7.07 ENST00000348974.5
ENST00000647936.1
ENST00000394236.9
ENST00000407433.6
protein S
chr3_-_52830664 6.99 ENST00000266041.9
ENST00000406595.5
ENST00000485816.5
inter-alpha-trypsin inhibitor heavy chain 4
chr16_+_72054477 6.87 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr3_-_93973933 6.40 ENST00000650591.1
protein S
chr12_-_7092422 6.26 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr12_-_7091873 6.21 ENST00000538050.5
ENST00000536053.6
complement C1r
chr3_-_149377637 5.83 ENST00000305366.8
transmembrane 4 L six family member 1
chr17_-_28370283 5.15 ENST00000226218.9
vitronectin
chr19_+_35282520 4.92 ENST00000222304.5
hepcidin antimicrobial peptide
chr1_-_67833448 4.88 ENST00000370982.4
G protein subunit gamma 12
chr17_+_79025612 4.87 ENST00000392445.6
C1q and TNF related 1
chr11_+_46719193 4.87 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
coagulation factor II, thrombin
chr5_+_40909490 4.52 ENST00000313164.10
complement C7
chr9_-_115118198 4.43 ENST00000534839.1
ENST00000535648.5
tenascin C
chr3_-_50611767 4.39 ENST00000443053.6
ENST00000348721.4
cytokine inducible SH2 containing protein
chr19_-_58353482 4.36 ENST00000263100.8
alpha-1-B glycoprotein
chr12_+_53050179 4.27 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chr19_-_4540028 4.14 ENST00000306390.7
leucine rich alpha-2-glycoprotein 1
chr9_-_115118145 4.13 ENST00000350763.9
tenascin C
chr11_+_57597563 4.10 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr17_+_34356472 4.05 ENST00000225844.7
C-C motif chemokine ligand 13
chr4_-_154612635 3.84 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
fibrinogen gamma chain
chr1_+_207089233 3.79 ENST00000243611.9
ENST00000367076.7
complement component 4 binding protein beta
chr7_-_88306880 3.60 ENST00000414498.1
ENST00000301959.9
ENST00000380079.9
STEAP4 metalloreductase
chr7_+_134779663 3.55 ENST00000361901.6
caldesmon 1
chr1_+_207089195 3.45 ENST00000452902.6
complement component 4 binding protein beta
chr7_+_134779625 3.38 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr16_-_10559135 3.37 ENST00000536829.1
epithelial membrane protein 2
chr11_+_76782250 3.30 ENST00000533752.1
ENST00000612930.1
tsukushi, small leucine rich proteoglycan
chr1_-_11047225 3.27 ENST00000400898.3
ENST00000400897.8
mannan binding lectin serine peptidase 2
chr4_+_154563003 3.00 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr17_+_34255274 2.97 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2
chr20_-_50691536 2.96 ENST00000327979.8
RIPOR family member 3
chr14_-_94452766 2.87 ENST00000334708.4
serpin family A member 11
chr12_+_53050014 2.80 ENST00000314250.11
tensin 2
chr1_+_207088825 2.74 ENST00000367078.8
complement component 4 binding protein beta
chr1_+_207089283 2.72 ENST00000391923.1
complement component 4 binding protein beta
chr1_-_6261053 2.58 ENST00000377893.3
G protein-coupled receptor 153
chrX_-_155334580 2.56 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr9_+_68356603 2.50 ENST00000396396.6
phosphoglucomutase 5
chr9_-_115091018 2.41 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
tenascin C
chr12_+_93570969 2.39 ENST00000536696.6
suppressor of cytokine signaling 2
chr1_-_153549238 2.34 ENST00000368713.8
S100 calcium binding protein A3
chr1_+_22653228 2.23 ENST00000509305.6
complement C1q B chain
chr3_-_64687613 2.23 ENST00000295903.8
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr1_-_153549120 2.19 ENST00000368712.1
S100 calcium binding protein A3
chr19_+_15107369 2.17 ENST00000342784.7
ENST00000597977.5
ENST00000600440.5
synapse defective Rho GTPase homolog 1
chr3_-_52826834 2.13 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chr5_-_123036664 2.08 ENST00000306442.5
peptidylprolyl isomerase C
chr1_+_22653189 2.05 ENST00000432749.6
complement C1q B chain
chr12_-_7109176 1.92 ENST00000545280.5
ENST00000543933.5
ENST00000545337.1
ENST00000266542.9
ENST00000544702.5
complement C1r subcomponent like
chrX_+_139530730 1.90 ENST00000218099.7
coagulation factor IX
chr9_-_101430861 1.80 ENST00000649902.1
aldolase, fructose-bisphosphate B
chr9_-_101442403 1.80 ENST00000648758.1
aldolase, fructose-bisphosphate B
chr19_+_10271093 1.76 ENST00000423829.2
ENST00000588645.1
ENST00000264832.8
intercellular adhesion molecule 1
chr14_-_106639589 1.76 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr7_+_100602344 1.75 ENST00000223061.6
procollagen C-endopeptidase enhancer
chr12_-_21775581 1.74 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr17_+_42760747 1.73 ENST00000589683.5
receptor activity modifying protein 2
chr5_-_140633167 1.73 ENST00000302014.11
CD14 molecule
chrX_+_139530752 1.72 ENST00000394090.2
coagulation factor IX
chr10_-_88991282 1.72 ENST00000458159.5
ENST00000415557.1
actin alpha 2, smooth muscle
chr10_-_100081854 1.72 ENST00000370418.8
carboxypeptidase N subunit 1
chr5_-_140633690 1.71 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr16_+_30985181 1.69 ENST00000262520.10
ENST00000297679.10
ENST00000562932.5
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_-_6440980 1.67 ENST00000265983.8
ENST00000615166.1
hemopexin
chr4_-_109801978 1.63 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr1_-_147773341 1.54 ENST00000430508.1
ENST00000621517.1
gap junction protein alpha 5
chr4_-_174522791 1.52 ENST00000541923.5
ENST00000542498.5
15-hydroxyprostaglandin dehydrogenase
chr3_-_146222337 1.47 ENST00000498625.1
phospholipid scramblase 4
chr1_-_203229660 1.45 ENST00000255427.7
ENST00000367229.6
chitinase 1
chr15_+_83654075 1.45 ENST00000567476.1
ENST00000286744.10
ADAMTS like 3
chr11_-_102798148 1.45 ENST00000315274.7
matrix metallopeptidase 1
chr9_-_101442372 1.44 ENST00000648423.1
aldolase, fructose-bisphosphate B
chr1_+_32247212 1.43 ENST00000373582.4
family with sequence similarity 167 member B
chr6_-_46921926 1.40 ENST00000283296.12
adhesion G protein-coupled receptor F5
chr17_+_19127535 1.39 ENST00000577213.1
ENST00000344415.9
GRB2 related adaptor protein like
chr19_-_48836475 1.39 ENST00000263278.9
ENST00000599157.5
hydroxysteroid 17-beta dehydrogenase 14
chr16_-_8861799 1.35 ENST00000610831.4
ENST00000614449.4
calcium regulated heat stable protein 1
chr1_-_154974361 1.35 ENST00000368453.8
ENST00000368450.5
SHC adaptor protein 1
chr19_-_15479469 1.34 ENST00000292609.8
ENST00000340880.5
peptidoglycan recognition protein 2
chr17_-_19046957 1.33 ENST00000284154.10
ENST00000573099.5
GRB2 related adaptor protein
chr4_+_54229261 1.31 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr7_+_117480011 1.31 ENST00000649406.1
ENST00000648260.1
ENST00000003084.11
CF transmembrane conductance regulator
chr11_+_63289897 1.30 ENST00000332793.11
solute carrier family 22 member 10
chr1_-_157552470 1.28 ENST00000361835.8
Fc receptor like 5
chr5_-_140633639 1.27 ENST00000498971.6
CD14 molecule
chr3_+_122680802 1.27 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr9_+_68356899 1.26 ENST00000396392.5
phosphoglucomutase 5
chr19_-_11578136 1.24 ENST00000589792.5
acid phosphatase 5, tartrate resistant
chr12_-_102917203 1.24 ENST00000553106.6
ENST00000307000.7
phenylalanine hydroxylase
chr17_+_42760805 1.22 ENST00000588928.1
receptor activity modifying protein 2
chr2_-_189179754 1.21 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr14_-_94293071 1.21 ENST00000554723.5
serpin family A member 10
chr14_-_20802836 1.21 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr14_-_94293024 1.20 ENST00000393096.5
serpin family A member 10
chr12_+_103930332 1.18 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
heat shock protein 90 beta family member 1
chr8_+_30442602 1.17 ENST00000520191.5
RNA binding protein, mRNA processing factor
chr8_-_119638780 1.17 ENST00000522826.5
ENST00000520066.5
ENST00000259486.10
ENST00000075322.11
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr14_+_94110728 1.15 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
interferon alpha inducible protein 27
chr7_+_117480052 1.15 ENST00000426809.5
ENST00000649781.1
CF transmembrane conductance regulator
chr1_-_1390943 1.15 ENST00000408952.8
cyclin L2
chr7_-_75813799 1.14 ENST00000222902.7
C-C motif chemokine ligand 24
chr16_-_8861713 1.13 ENST00000567554.5
calcium regulated heat stable protein 1
chr14_-_20802402 1.11 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr16_+_67227105 1.11 ENST00000563953.5
ENST00000304800.14
ENST00000565201.1
transmembrane protein 208
chr1_+_161663147 1.10 ENST00000236937.13
ENST00000367961.8
ENST00000358671.9
Fc fragment of IgG receptor IIb
chrX_-_66033664 1.10 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr1_+_53062052 1.10 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
podocan
chr2_-_88966767 1.08 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr17_+_81804125 1.08 ENST00000570996.5
ENST00000400723.8
glucagon receptor
chr3_-_146222426 1.08 ENST00000481701.5
phospholipid scramblase 4
chr8_-_70245343 1.07 ENST00000519724.1
nuclear receptor coactivator 2
chr14_-_94293260 1.06 ENST00000261994.9
serpin family A member 10
chr11_-_119340544 1.06 ENST00000530681.2
C1q and TNF related 5
chr14_+_75985747 1.05 ENST00000679083.1
ENST00000314067.11
ENST00000238628.10
ENST00000556742.1
intraflagellar transport 43
chr22_-_50261272 1.03 ENST00000395780.5
mitogen-activated protein kinase 12
chr22_-_31107517 1.03 ENST00000400299.6
ENST00000611680.1
selenoprotein M
chr10_-_34815257 1.02 ENST00000374789.8
ENST00000374788.8
ENST00000346874.9
ENST00000374794.8
ENST00000350537.9
ENST00000374790.8
ENST00000374776.6
ENST00000374773.6
ENST00000545260.5
ENST00000545693.5
ENST00000340077.9
par-3 family cell polarity regulator
chr3_-_49723903 1.02 ENST00000678010.1
ENST00000480687.5
ENST00000308388.7
ENST00000308375.10
ENST00000677393.1
ENST00000495627.2
GDP-mannose pyrophosphorylase B
chr5_+_150508110 1.02 ENST00000261797.7
N-deacetylase and N-sulfotransferase 1
chr8_-_6563238 1.01 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr12_-_102917114 1.00 ENST00000550978.6
phenylalanine hydroxylase
chr22_+_38201932 1.00 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAF bZIP transcription factor F
chr1_-_154974324 0.99 ENST00000412170.5
SHC adaptor protein 1
chr3_-_194351290 0.98 ENST00000429275.1
ENST00000323830.4
carboxypeptidase N subunit 2
chr11_+_7485606 0.98 ENST00000528758.1
olfactomedin like 1
chr11_-_102874974 0.97 ENST00000571244.3
matrix metallopeptidase 12
chr14_-_106875069 0.94 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr11_+_57763820 0.94 ENST00000674106.1
catenin delta 1
chr8_-_6563409 0.94 ENST00000325203.9
angiopoietin 2
chr5_-_135578983 0.93 ENST00000512158.6
C-X-C motif chemokine ligand 14
chr12_-_91146195 0.93 ENST00000548218.1
decorin
chr1_+_15756659 0.93 ENST00000375771.5
filamin binding LIM protein 1
chr19_-_4717887 0.92 ENST00000599248.1
dipeptidyl peptidase 9
chr1_-_160647037 0.91 ENST00000302035.11
signaling lymphocytic activation molecule family member 1
chr2_+_168802610 0.91 ENST00000397206.6
ENST00000317647.12
ENST00000397209.6
nitric oxide synthase trafficking
chr14_-_106012390 0.90 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr14_-_24508251 0.90 ENST00000250378.7
ENST00000206446.4
chymase 1
chr9_-_121050264 0.86 ENST00000223642.3
complement C5
chr16_+_85899121 0.85 ENST00000268638.10
ENST00000565552.1
interferon regulatory factor 8
chr5_+_149141817 0.85 ENST00000504238.5
actin binding LIM protein family member 3
chr8_-_6563044 0.83 ENST00000338312.10
angiopoietin 2
chr1_-_161238085 0.83 ENST00000512372.5
ENST00000437437.6
ENST00000412844.6
ENST00000428574.6
ENST00000442691.6
ENST00000505005.5
ENST00000508740.5
ENST00000367981.7
ENST00000502985.5
ENST00000504010.5
ENST00000508387.5
ENST00000511676.5
ENST00000511748.5
ENST00000511944.5
ENST00000515621.5
ENST00000367984.8
ENST00000367985.7
nuclear receptor subfamily 1 group I member 3
chr15_+_58410543 0.83 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr5_+_149141890 0.83 ENST00000508983.5
actin binding LIM protein family member 3
chr4_+_67558719 0.82 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr12_+_52010485 0.82 ENST00000552049.5
ENST00000546756.1
trafficking regulator and scaffold protein tamalin
chr1_-_203186677 0.82 ENST00000255409.8
chitinase 3 like 1
chr6_-_39229465 0.81 ENST00000359534.4
potassium two pore domain channel subfamily K member 5
chr3_+_45026296 0.81 ENST00000296130.5
C-type lectin domain family 3 member B
chr7_-_74851518 0.81 ENST00000651129.1
ENST00000614386.1
ENST00000625377.2
ENST00000451013.7
GTF2I repeat domain containing 2
chr12_-_47819952 0.81 ENST00000417902.5
histone deacetylase 7
chr19_+_10086305 0.80 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr12_+_103930600 0.79 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr6_-_6006878 0.79 ENST00000244766.7
neuritin 1
chr19_+_11089446 0.79 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
low density lipoprotein receptor
chr14_-_20413420 0.78 ENST00000556935.5
ENST00000556549.1
ENST00000262715.10
telomerase associated protein 1
chr16_-_8861744 0.78 ENST00000569398.5
ENST00000568968.1
calcium regulated heat stable protein 1
chr6_-_119349754 0.78 ENST00000368468.4
mannosidase alpha class 1A member 1
chr8_-_85341659 0.78 ENST00000522389.5
carbonic anhydrase 1
chr1_-_156601435 0.77 ENST00000438976.6
ENST00000368232.9
ENST00000415314.6
G-patch domain containing 4
chr8_-_85341705 0.76 ENST00000517618.5
carbonic anhydrase 1
chr9_+_68357100 0.76 ENST00000431583.1
phosphoglucomutase 5
chr19_+_10086787 0.76 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr19_-_11577632 0.75 ENST00000590420.1
ENST00000648477.1
acid phosphatase 5, tartrate resistant
chr1_-_150808251 0.75 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr11_+_844067 0.75 ENST00000397406.5
ENST00000409543.6
ENST00000525201.5
tetraspanin 4
chr3_-_120682113 0.75 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr6_+_26103922 0.73 ENST00000377803.4
H4 clustered histone 3
chr9_+_35791570 0.73 ENST00000342694.7
natriuretic peptide receptor 2
chr2_+_17753852 0.73 ENST00000317402.11
GEN1 Holliday junction 5' flap endonuclease
chr1_-_160646958 0.73 ENST00000538290.2
signaling lymphocytic activation molecule family member 1
chr1_+_99646025 0.73 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr5_-_140633656 0.72 ENST00000519715.1
CD14 molecule
chr4_-_2756288 0.71 ENST00000510267.5
ENST00000315423.12
ENST00000503235.1
TNFAIP3 interacting protein 2
chr4_+_165378998 0.71 ENST00000402744.9
carboxypeptidase E
chr17_+_78187317 0.71 ENST00000409257.9
ENST00000591256.5
ENST00000589256.5
ENST00000588800.5
ENST00000591952.5
ENST00000327898.9
ENST00000586542.5
ENST00000586731.1
arylformamidase
chr2_-_166375901 0.70 ENST00000303354.11
ENST00000645907.1
ENST00000642356.2
ENST00000452182.2
sodium voltage-gated channel alpha subunit 9
chr11_+_73292755 0.70 ENST00000680955.1
ENST00000538328.2
pyrimidinergic receptor P2Y6
chr6_+_44227025 0.70 ENST00000371708.1
solute carrier family 29 member 1 (Augustine blood group)
chr13_+_110424798 0.70 ENST00000619688.2
collagen type IV alpha 2 chain
chr2_-_218010202 0.69 ENST00000646520.1
tensin 1
chr1_+_1435523 0.69 ENST00000338660.5
ENST00000476993.2
ENST00000471398.1
von Willebrand factor A domain containing 1
chr1_+_213989691 0.69 ENST00000607425.1
prospero homeobox 1
chr20_-_45891200 0.68 ENST00000372518.5
neuralized E3 ubiquitin protein ligase 2
chr3_-_112610262 0.68 ENST00000479368.1
coiled-coil domain containing 80
chr17_-_48545077 0.68 ENST00000330070.6
homeobox B2
chr2_-_166375969 0.68 ENST00000454569.6
ENST00000409672.5
sodium voltage-gated channel alpha subunit 9
chr12_-_55727080 0.67 ENST00000548898.5
ENST00000552067.5
CD63 molecule
chrX_-_2964252 0.67 ENST00000681963.1
ENST00000684738.1
ENST00000438544.5
ENST00000682184.1
ENST00000545496.6
ENST00000684364.1
ENST00000683677.1
ENST00000683290.1
ENST00000682364.1
arylsulfatase L
chr4_+_54229843 0.66 ENST00000503856.5
platelet derived growth factor receptor alpha
chr8_-_133102477 0.66 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
Src like adaptor
chr10_+_35195843 0.65 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr11_+_71999927 0.65 ENST00000393707.4
interleukin 18 binding protein
chr8_+_81732434 0.65 ENST00000297265.5
charged multivesicular body protein 4C

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
2.8 8.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
2.3 6.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
2.1 8.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
1.7 5.1 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
1.6 4.9 GO:1990641 response to iron ion starvation(GO:1990641)
1.4 12.7 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
1.0 5.2 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801)
1.0 4.1 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.0 3.0 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.9 2.8 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.9 12.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.8 17.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.7 4.9 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 5.4 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.7 3.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.7 2.0 GO:0031247 actin rod assembly(GO:0031247)
0.6 2.5 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.6 3.5 GO:0008218 bioluminescence(GO:0008218)
0.5 2.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.5 3.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 1.5 GO:0003193 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.5 4.9 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 2.4 GO:0030070 insulin processing(GO:0030070)
0.4 1.3 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.4 1.6 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.4 2.0 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.4 6.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.3 1.0 GO:0046041 ITP metabolic process(GO:0046041)
0.3 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 0.9 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.3 0.9 GO:0061569 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.3 1.7 GO:0090131 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.3 3.4 GO:0070836 caveola assembly(GO:0070836)
0.3 0.8 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.3 2.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 2.9 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 5.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 2.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3 0.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 1.8 GO:0022614 membrane to membrane docking(GO:0022614)
0.3 0.8 GO:0019303 D-ribose catabolic process(GO:0019303)
0.3 4.5 GO:0019388 galactose catabolic process(GO:0019388)
0.2 7.2 GO:0006825 copper ion transport(GO:0006825)
0.2 3.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 0.7 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 0.7 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.6 GO:0035697 CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) T cell extravasation(GO:0072683) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.2 1.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 1.2 GO:0015862 uridine transport(GO:0015862)
0.2 0.8 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 0.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 3.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 7.1 GO:0014850 response to muscle activity(GO:0014850)
0.2 1.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.2 0.6 GO:0019089 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.2 0.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 4.7 GO:0031639 plasminogen activation(GO:0031639)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.9 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 0.7 GO:0021569 rhombomere 3 development(GO:0021569)
0.2 0.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 22.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.7 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 0.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 2.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 3.0 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 2.6 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.5 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.9 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 2.0 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.5 GO:0097032 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 1.4 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.5 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 1.2 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.4 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.1 0.5 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 8.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.3 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.1 0.2 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 1.0 GO:1902739 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 0.5 GO:0046878 response to ozone(GO:0010193) operant conditioning(GO:0035106) positive regulation of saliva secretion(GO:0046878)
0.1 1.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 4.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 1.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.0 GO:0010269 response to selenium ion(GO:0010269)
0.1 1.3 GO:0015747 urate transport(GO:0015747)
0.1 2.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.1 2.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 1.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.9 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 1.6 GO:0007567 parturition(GO:0007567)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 4.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.0 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.9 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.4 GO:0019075 virus maturation(GO:0019075)
0.1 0.4 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.2 GO:0060876 semicircular canal formation(GO:0060876)
0.1 0.2 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of hair follicle maturation(GO:0048817) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.6 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 1.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 0.7 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 0.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.4 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 1.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.7 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.5 GO:1902527 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.4 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 1.3 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.6 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.9 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.6 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 1.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 3.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 2.0 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 1.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 1.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.8 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 2.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 1.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.9 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0019626 cobalamin biosynthetic process(GO:0009236) short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.5 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 2.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0033632 negative regulation of extracellular matrix disassembly(GO:0010716) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.6 GO:0048536 spleen development(GO:0048536)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117) positive regulation of Schwann cell differentiation(GO:0014040) response to cobalamin(GO:0033590)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.5 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 1.8 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.0 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 2.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 1.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.3 GO:0030220 platelet formation(GO:0030220)
0.0 0.9 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.7 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.7 5.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.5 4.5 GO:0005914 spot adherens junction(GO:0005914)
1.2 16.2 GO:0005577 fibrinogen complex(GO:0005577)
1.1 4.3 GO:0005602 complement component C1 complex(GO:0005602)
0.6 5.4 GO:0005579 membrane attack complex(GO:0005579)
0.5 6.9 GO:0030478 actin cap(GO:0030478)
0.5 5.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 9.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 2.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.4 3.0 GO:0070435 Shc-EGFR complex(GO:0070435)
0.4 3.0 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.3 12.8 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 0.8 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 1.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 58.9 GO:0072562 blood microparticle(GO:0072562)
0.2 4.0 GO:0045179 apical cortex(GO:0045179)
0.2 0.8 GO:0035517 PR-DUB complex(GO:0035517)
0.2 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.1 GO:0036021 endolysosome lumen(GO:0036021)
0.2 2.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 3.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 2.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 5.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 13.3 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 1.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 5.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.6 GO:0042627 chylomicron(GO:0042627)
0.1 1.2 GO:0005915 zonula adherens(GO:0005915)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.0 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 4.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 6.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0090543 Flemming body(GO:0090543)
0.0 1.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 4.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.4 GO:0070449 Cul5-RING ubiquitin ligase complex(GO:0031466) elongin complex(GO:0070449)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 2.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.0 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 8.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 27.0 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 9.7 GO:0005925 focal adhesion(GO:0005925)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.3 5.0 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.2 11.0 GO:0045545 syndecan binding(GO:0045545)
1.0 6.9 GO:0030492 hemoglobin binding(GO:0030492)
0.8 6.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.8 3.3 GO:0001855 complement component C4b binding(GO:0001855)
0.7 7.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 2.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.6 3.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.6 4.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.5 1.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4 1.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.4 2.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 2.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.4 3.0 GO:0097643 amylin receptor activity(GO:0097643)
0.3 8.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 2.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3 1.5 GO:0055077 gap junction hemi-channel activity(GO:0055077) gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.3 1.5 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 4.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.3 1.8 GO:0004882 androgen receptor activity(GO:0004882)
0.3 1.7 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.3 1.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 1.1 GO:0019770 IgG receptor activity(GO:0019770)
0.3 3.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 1.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.3 2.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 0.8 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 0.7 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
0.2 4.9 GO:0042301 phosphate ion binding(GO:0042301)
0.2 1.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 1.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 7.0 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 0.6 GO:0017129 triglyceride binding(GO:0017129)
0.2 1.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 1.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 1.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.2 1.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.9 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 2.4 GO:0008199 ferric iron binding(GO:0008199)
0.2 4.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 1.5 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.6 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 2.0 GO:0046790 virion binding(GO:0046790)
0.1 2.3 GO:0004568 chitinase activity(GO:0004568)
0.1 0.9 GO:0042806 fucose binding(GO:0042806)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 19.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 8.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.7 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 2.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.9 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 14.1 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 2.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.8 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.3 GO:0019785 ISG15-specific protease activity(GO:0019785)
0.1 0.5 GO:0050051 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.6 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 28.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.6 GO:0061135 endopeptidase regulator activity(GO:0061135)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.4 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 2.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 4.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.9 GO:0031005 filamin binding(GO:0031005)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 3.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 8.7 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 1.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 4.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 4.4 GO:0019210 kinase inhibitor activity(GO:0019210)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 4.9 GO:0005178 integrin binding(GO:0005178)
0.0 2.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 7.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.9 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.8 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 1.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 32.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 4.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 4.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 10.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 10.5 PID IL23 PATHWAY IL23-mediated signaling events
0.1 5.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 12.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 35.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 6.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 9.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 15.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 9.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 34.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 14.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 7.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 5.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 8.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 1.3 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.3 7.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 5.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 3.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 7.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 5.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 6.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 8.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 18.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 2.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 9.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 4.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway