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Illumina Body Map 2 (GSE30611)

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Results for STAT4

Z-value: 0.65

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Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
ENSG00000138378.19 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT4hg38_v1_chr2_-_191150971_191151017-0.057.7e-01Click!

Activity profile of STAT4 motif

Sorted Z-values of STAT4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_49744378 1.83 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr19_+_35282520 1.75 ENST00000222304.5
hepcidin antimicrobial peptide
chrX_-_140784366 1.65 ENST00000674533.1
cerebellar degeneration related protein 1
chr11_-_118176576 1.37 ENST00000278947.6
sodium voltage-gated channel beta subunit 2
chr3_-_196515315 1.37 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr4_-_76036060 1.22 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr3_-_98517096 1.08 ENST00000513873.1
claudin domain containing 1
chr4_+_168654724 1.04 ENST00000503457.1
palladin, cytoskeletal associated protein
chr6_-_56851888 0.98 ENST00000312431.10
ENST00000520645.5
dystonin
chr1_+_202462730 0.97 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chr1_-_161367872 0.92 ENST00000367974.2
cilia and flagella associated protein 126
chr4_-_154612635 0.84 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
fibrinogen gamma chain
chr11_-_120128831 0.82 ENST00000529044.5
tripartite motif containing 29
chr4_+_157220691 0.82 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
glutamate ionotropic receptor AMPA type subunit 2
chr15_+_63048576 0.79 ENST00000559281.6
tropomyosin 1
chr18_-_27990256 0.77 ENST00000675173.1
cadherin 2
chr6_+_101181254 0.75 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr9_-_92404559 0.72 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr1_-_109112733 0.70 ENST00000369948.8
ENST00000369945.7
chromosome 1 open reading frame 194
chr15_+_63048658 0.65 ENST00000560615.5
ENST00000651577.1
tropomyosin 1
chr5_+_90899183 0.65 ENST00000640815.1
adhesion G protein-coupled receptor V1
chr4_+_157220654 0.63 ENST00000393815.6
glutamate ionotropic receptor AMPA type subunit 2
chr8_-_27611866 0.58 ENST00000519742.5
clusterin
chr3_-_165196369 0.58 ENST00000475390.2
SLIT and NTRK like family member 3
chr5_+_36606355 0.56 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr4_-_46124046 0.55 ENST00000295452.5
gamma-aminobutyric acid type A receptor subunit gamma1
chr6_+_133889105 0.53 ENST00000367882.5
transcription factor 21
chr1_+_121087343 0.53 ENST00000616817.4
ENST00000623603.3
ENST00000369384.9
ENST00000369383.8
ENST00000369178.5
Fc fragment of IgG receptor Ib
chr10_-_102419693 0.51 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr2_+_233917371 0.51 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr11_-_31804067 0.51 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
paired box 6
chr15_+_63048436 0.51 ENST00000334895.10
ENST00000404484.9
ENST00000558910.3
ENST00000317516.12
tropomyosin 1
chr14_-_21022095 0.50 ENST00000635386.1
NDRG family member 2
chr18_+_63476927 0.50 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr10_-_102419934 0.50 ENST00000406432.5
pleckstrin and Sec7 domain containing
chr1_+_155173787 0.50 ENST00000392451.6
ENST00000545012.5
ENST00000334634.9
ENST00000368385.8
ENST00000543729.5
ENST00000368383.7
ENST00000368382.5
tripartite motif containing 46
chr3_+_50611871 0.50 ENST00000446044.5
MAPK activated protein kinase 3
chr2_+_209580024 0.48 ENST00000392194.5
microtubule associated protein 2
chr6_+_30888672 0.48 ENST00000446312.5
discoidin domain receptor tyrosine kinase 1
chr11_-_120138104 0.48 ENST00000341846.10
tripartite motif containing 29
chr7_-_83162899 0.47 ENST00000423517.6
piccolo presynaptic cytomatrix protein
chr16_-_46748337 0.47 ENST00000394809.9
myosin light chain kinase 3
chr16_+_58249910 0.47 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr14_-_21022494 0.47 ENST00000449431.6
NDRG family member 2
chr14_-_21022258 0.47 ENST00000556366.5
NDRG family member 2
chr5_-_161546708 0.46 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chr1_-_230745574 0.46 ENST00000681269.1
angiotensinogen
chrX_+_139530730 0.46 ENST00000218099.7
coagulation factor IX
chrX_+_139530752 0.45 ENST00000394090.2
coagulation factor IX
chr14_-_21022432 0.45 ENST00000557633.5
NDRG family member 2
chr5_+_141343818 0.45 ENST00000619750.1
ENST00000253812.8
protocadherin gamma subfamily A, 3
chr16_+_78022538 0.44 ENST00000651443.1
ENST00000299642.10
C-type lectin domain family 3 member A
chr9_-_113401249 0.43 ENST00000409155.8
ENST00000448137.5
aminolevulinate dehydratase
chr7_-_83162857 0.42 ENST00000333891.14
piccolo presynaptic cytomatrix protein
chr5_-_22853320 0.42 ENST00000504376.6
ENST00000382254.6
cadherin 12
chrX_-_63785510 0.42 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr19_+_34677639 0.41 ENST00000627982.2
ENST00000613363.4
ENST00000502743.5
ENST00000509528.5
ENST00000506901.5
ENST00000457781.6
ENST00000505163.5
ENST00000505242.6
ENST00000423823.6
ENST00000507959.5
ENST00000446502.6
zinc finger protein 302
chr19_-_34677157 0.41 ENST00000601241.6
secretoglobin family 2B member 2
chrX_+_136487940 0.40 ENST00000370648.4
bombesin receptor subtype 3
chr1_+_149782671 0.40 ENST00000444948.5
ENST00000369168.5
Fc fragment of IgG receptor Ia
chr3_+_171843337 0.40 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr6_-_123636997 0.40 ENST00000546248.5
triadin
chr2_+_113127588 0.40 ENST00000409930.4
interleukin 1 receptor antagonist
chr7_-_83649097 0.39 ENST00000643230.2
semaphorin 3E
chr8_-_27611200 0.39 ENST00000520796.5
ENST00000520491.5
clusterin
chr3_-_149221811 0.39 ENST00000455472.3
ENST00000264613.11
ceruloplasmin
chr8_-_27611679 0.38 ENST00000560566.5
clusterin
chr19_+_34677723 0.37 ENST00000505365.2
zinc finger protein 302
chr5_-_161546970 0.37 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr17_-_81128873 0.36 ENST00000572339.5
apoptosis associated tyrosine kinase
chr1_+_66330711 0.36 ENST00000528771.5
phosphodiesterase 4B
chr15_+_63048535 0.35 ENST00000560959.5
tropomyosin 1
chr22_-_31140494 0.35 ENST00000215885.4
phospholipase A2 group III
chr14_-_21022817 0.34 ENST00000554104.5
NDRG family member 2
chr19_+_10086305 0.34 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr19_-_44448435 0.33 ENST00000588655.1
ENST00000592308.1
ENST00000614049.5
ENST00000613197.4
novel transcript
zinc finger protein 229
chr20_+_8132138 0.33 ENST00000378641.7
ENST00000338037.11
ENST00000629992.2
phospholipase C beta 1
chr3_+_45388613 0.33 ENST00000430399.1
leucyl-tRNA synthetase 2, mitochondrial
chr8_-_27611424 0.33 ENST00000405140.7
clusterin
chr19_+_34734155 0.32 ENST00000599244.5
ENST00000392232.7
ENST00000492450.3
ENST00000595708.5
ENST00000593781.5
zinc finger protein 181
chr12_-_54973683 0.32 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
thymocyte expressed, positive selection associated 1
chr8_-_42501224 0.32 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr19_+_679894 0.32 ENST00000589185.2
follistatin like 3
chr11_-_85627268 0.32 ENST00000650630.1
discs large MAGUK scaffold protein 2
chr6_+_143126183 0.31 ENST00000458219.1
androgen induced 1
chr17_-_7261092 0.31 ENST00000574070.5
claudin 7
chr6_-_32184287 0.31 ENST00000375069.7
ENST00000375070.7
ENST00000438221.6
ENST00000620802.4
ENST00000538695.2
advanced glycosylation end-product specific receptor
chr12_+_20695469 0.31 ENST00000545604.5
solute carrier organic anion transporter family member 1C1
chr1_-_190475981 0.31 ENST00000631494.1
BMP/retinoic acid inducible neural specific 3
chr5_-_140633656 0.30 ENST00000519715.1
CD14 molecule
chr15_+_44728985 0.30 ENST00000559390.5
tripartite motif containing 69
chr12_+_20695323 0.30 ENST00000266509.7
solute carrier organic anion transporter family member 1C1
chr8_-_27611325 0.30 ENST00000523500.5
clusterin
chr1_-_225877630 0.30 ENST00000436966.1
transmembrane protein 63A
chr10_+_113553039 0.30 ENST00000351270.4
hyaluronan binding protein 2
chr1_+_115976488 0.29 ENST00000369503.9
solute carrier family 22 member 15
chr6_+_154995258 0.29 ENST00000682666.1
TIAM Rac1 associated GEF 2
chr14_+_20343607 0.29 ENST00000250416.9
ENST00000429687.8
ENST00000527915.5
poly(ADP-ribose) polymerase 2
chr12_+_20695442 0.29 ENST00000540354.5
solute carrier organic anion transporter family member 1C1
chr5_-_140633639 0.28 ENST00000498971.6
CD14 molecule
chr12_-_54973547 0.28 ENST00000526532.5
ENST00000532757.5
thymocyte expressed, positive selection associated 1
chr1_+_232950580 0.28 ENST00000366628.10
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr15_+_65550819 0.28 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr8_+_22056966 0.27 ENST00000517804.5
dematin actin binding protein
chr5_+_137867852 0.27 ENST00000421631.6
ENST00000239926.9
myotilin
chr9_-_114074969 0.27 ENST00000466610.6
alpha-1-microglobulin/bikunin precursor
chr12_+_20695553 0.27 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr2_-_40453438 0.27 ENST00000455476.5
solute carrier family 8 member A1
chr6_-_109690515 0.26 ENST00000532976.1
adenylate kinase 9
chr3_-_52830664 0.26 ENST00000266041.9
ENST00000406595.5
ENST00000485816.5
inter-alpha-trypsin inhibitor heavy chain 4
chr1_+_17580474 0.26 ENST00000375415.5
Rho guanine nucleotide exchange factor 10 like
chr8_+_22056837 0.26 ENST00000520174.5
dematin actin binding protein
chr1_-_230869564 0.25 ENST00000470540.5
chromosome 1 open reading frame 198
chr19_+_10086787 0.25 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr19_+_44165067 0.25 ENST00000590578.5
ENST00000589160.5
ENST00000586286.5
ENST00000337433.10
ENST00000585560.5
ENST00000586914.5
ENST00000588883.5
ENST00000413984.6
ENST00000588742.5
ENST00000300823.10
ENST00000585678.5
ENST00000586203.5
ENST00000590467.5
ENST00000588795.5
ENST00000588127.5
zinc finger protein 226
chr9_-_83267230 0.25 ENST00000328788.5
FERM domain containing 3
chr14_-_100375333 0.24 ENST00000557297.5
ENST00000555813.5
ENST00000392882.7
ENST00000557135.5
ENST00000556698.5
ENST00000554509.5
ENST00000555410.5
tryptophanyl-tRNA synthetase 1
chr16_+_69424634 0.24 ENST00000515314.6
ENST00000561792.6
ENST00000568237.1
cytochrome b5 type B
chr5_-_140633690 0.24 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr12_-_14929116 0.24 ENST00000540097.1
endoplasmic reticulum protein 27
chr6_+_139028838 0.24 ENST00000461027.1
ABRA C-terminal like
chr5_+_132073782 0.24 ENST00000296871.4
colony stimulating factor 2
chr5_-_161546671 0.24 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr12_-_9999176 0.23 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr3_+_77039836 0.23 ENST00000461745.5
roundabout guidance receptor 2
chr17_-_44916915 0.23 ENST00000593179.1
glial fibrillary acidic protein
chr11_+_20022829 0.23 ENST00000525322.5
ENST00000530408.1
neuron navigator 2
chr6_-_123636979 0.23 ENST00000662930.1
triadin
chr14_-_100375602 0.22 ENST00000553395.5
ENST00000553545.5
ENST00000344102.9
ENST00000556338.5
ENST00000553934.1
tryptophanyl-tRNA synthetase 1
chr3_+_45388555 0.22 ENST00000650792.2
ENST00000414984.5
ENST00000645846.2
leucyl-tRNA synthetase 2, mitochondrial
chr19_+_39997031 0.22 ENST00000599504.5
ENST00000596894.5
ENST00000601138.5
ENST00000347077.9
ENST00000600094.5
zinc finger protein 546
chr12_-_51009264 0.21 ENST00000545993.7
solute carrier family 11 member 2
chr10_+_104269163 0.21 ENST00000338595.7
glutathione S-transferase omega 2
chr4_-_176241671 0.21 ENST00000512254.1
ankyrin repeat and SOCS box containing 5
chr3_+_122680850 0.21 ENST00000494811.2
poly(ADP-ribose) polymerase family member 14
chr15_+_47759723 0.20 ENST00000559196.1
semaphorin 6D
chr5_+_140882116 0.20 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr5_+_137867868 0.20 ENST00000515645.1
myotilin
chr19_-_58353482 0.19 ENST00000263100.8
alpha-1-B glycoprotein
chr7_-_108528155 0.19 ENST00000453085.1
patatin like phospholipase domain containing 8
chr6_-_123636966 0.19 ENST00000542443.5
triadin
chr8_-_109648825 0.18 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr6_-_123636906 0.18 ENST00000628709.2
triadin
chr4_-_154590735 0.18 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr12_+_59689337 0.18 ENST00000261187.8
solute carrier family 16 member 7
chr1_+_161581339 0.17 ENST00000543859.5
ENST00000611236.1
Fc fragment of IgG receptor IIc (gene/pseudogene)
chr20_-_25339731 0.17 ENST00000450393.5
ENST00000491682.5
abhydrolase domain containing 12, lysophospholipase
chr7_-_38929550 0.17 ENST00000418457.6
VPS41 subunit of HOPS complex
chr5_+_90640718 0.17 ENST00000640403.1
adhesion G protein-coupled receptor V1
chr20_+_5750437 0.16 ENST00000445603.1
ENST00000442185.1
shieldin complex subunit 1
chr1_+_161663147 0.16 ENST00000236937.13
ENST00000367961.8
ENST00000358671.9
Fc fragment of IgG receptor IIb
chr4_-_83012846 0.16 ENST00000510557.5
lin-54 DREAM MuvB core complex component
chr1_+_50105666 0.16 ENST00000651347.1
ELAV like RNA binding protein 4
chr14_+_69191760 0.16 ENST00000409949.5
ENST00000312994.9
ENST00000409242.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr1_+_15236509 0.15 ENST00000683790.1
forkhead associated phosphopeptide binding domain 1
chr12_+_27243968 0.15 ENST00000541191.5
serine/threonine kinase 38 like
chr11_-_118565992 0.15 ENST00000264020.6
intraflagellar transport 46
chr3_+_130345516 0.15 ENST00000265379.10
collagen type VI alpha 5 chain
chr7_+_117480011 0.15 ENST00000649406.1
ENST00000648260.1
ENST00000003084.11
CF transmembrane conductance regulator
chr17_+_29593118 0.15 ENST00000394859.8
ankyrin repeat domain 13B
chr8_-_109648746 0.15 ENST00000528045.5
syntabulin
chr12_-_11022620 0.14 ENST00000390673.2
taste 2 receptor member 19
chr10_-_114685000 0.14 ENST00000369256.6
actin binding LIM protein 1
chr19_-_56393430 0.14 ENST00000589895.1
ENST00000589143.5
ENST00000301310.8
ENST00000586929.5
zinc finger protein 582
chr3_-_187737943 0.13 ENST00000438077.1
BCL6 transcription repressor
chr4_+_129096113 0.13 ENST00000508673.5
chromosome 4 open reading frame 33
chr10_-_114684457 0.13 ENST00000392955.7
actin binding LIM protein 1
chr10_-_114684612 0.13 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr1_+_50106265 0.13 ENST00000357083.8
ELAV like RNA binding protein 4
chr6_-_109690500 0.13 ENST00000448084.6
adenylate kinase 9
chr12_+_57745017 0.12 ENST00000547992.5
ENST00000552816.5
ENST00000257910.8
ENST00000547472.5
tetraspanin 31
chr9_+_97307645 0.11 ENST00000529487.3
coiled-coil domain containing 180
chr2_+_188292771 0.11 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr16_-_1610661 0.11 ENST00000569646.5
intraflagellar transport 140
chr15_+_57706670 0.11 ENST00000299638.8
RNA polymerase II subunit M
chr19_+_39391323 0.11 ENST00000615911.4
ENST00000315588.11
ENST00000594368.5
ENST00000596297.1
mediator complex subunit 29
chr4_+_129096144 0.11 ENST00000425929.6
ENST00000508622.1
chromosome 4 open reading frame 33
chr6_+_36676455 0.11 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr12_-_122174214 0.10 ENST00000377035.2
interleukin 31
chr20_+_43507668 0.09 ENST00000434666.5
ENST00000649084.1
ENST00000418998.7
ENST00000427442.8
ENST00000649917.1
L3MBTL histone methyl-lysine binding protein 1
chr17_-_42980393 0.09 ENST00000409446.8
ENST00000409399.6
ENST00000421990.7
prostaglandin E synthase 3 like
PTGES3L-AARSD1 readthrough
chr15_+_57706725 0.09 ENST00000380557.4
ENST00000649091.1
RNA polymerase II subunit M
chr5_-_128339191 0.09 ENST00000507835.5
fibrillin 2
chr6_+_36676489 0.09 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr2_-_201769759 0.09 ENST00000680163.1
ENST00000680188.1
ENST00000679550.1
alsin Rho guanine nucleotide exchange factor ALS2
chr3_-_108953762 0.09 ENST00000393963.7
ENST00000471108.1
guanylate cyclase activator 1C
chr3_+_108296535 0.09 ENST00000463019.7
ENST00000491820.5
ENST00000467562.5
ENST00000482430.5
ENST00000462629.5
HERV-H LTR-associating 2
chr3_+_108296489 0.08 ENST00000619531.4
HERV-H LTR-associating 2
chr17_+_5420172 0.08 ENST00000381209.8
ENST00000405578.8
ENST00000574003.1
RPA interacting protein
chr11_+_64924673 0.08 ENST00000164133.7
ENST00000532850.1
protein phosphatase 2 regulatory subunit B'beta
chr12_+_133080409 0.08 ENST00000356456.9
zinc finger protein 140
chrX_+_106802660 0.07 ENST00000357242.10
ENST00000310452.6
ENST00000481617.6
ENST00000276175.7
TBC1 domain family member 8B
chr11_+_73308237 0.07 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr2_-_240821363 0.07 ENST00000675940.1
kinesin family member 1A
chr3_-_184017863 0.07 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr14_+_99773698 0.07 ENST00000556199.1
EMAP like 1
chr21_+_34364003 0.07 ENST00000290310.4
potassium voltage-gated channel subfamily E regulatory subunit 2
chr20_+_56630200 0.07 ENST00000416606.1
transcription factor AP-2 gamma
chr4_-_139084289 0.06 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chr1_+_149583865 0.06 ENST00000585245.2
peptidylprolyl isomerase A like 4C

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1990641 response to iron ion starvation(GO:1990641)
0.5 2.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.3 0.9 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 2.0 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 1.0 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.2 0.5 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 1.4 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.5 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.4 GO:0070541 response to platinum ion(GO:0070541)
0.1 0.4 GO:0061568 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 2.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.3 GO:2000438 CD24 biosynthetic process(GO:0035724) activation of meiosis involved in egg activation(GO:0060466) negative regulation of monocyte extravasation(GO:2000438) regulation of CD24 biosynthetic process(GO:2000559) positive regulation of CD24 biosynthetic process(GO:2000560)
0.1 0.9 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.3 GO:1904604 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.1 0.6 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.8 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.2 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) follicular B cell differentiation(GO:0002316) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.0 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.2 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.2 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 1.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 2.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.3 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.2 1.4 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 2.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 1.0 GO:0031673 H zone(GO:0031673)
0.1 1.7 GO:0045179 apical cortex(GO:0045179)
0.1 0.5 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.0 GO:0033018 junctional membrane complex(GO:0030314) sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 1.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 1.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 1.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.9 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.3 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.1 1.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 2.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0019864 IgG binding(GO:0019864)
0.0 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.3 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.9 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0019862 IgA binding(GO:0019862)
0.0 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.4 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 1.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+