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Illumina Body Map 2 (GSE30611)

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Results for STAT6

Z-value: 1.04

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
ENSG00000166888.12 signal transducer and activator of transcription 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg38_v1_chr12_-_57111338_57111433-0.154.2e-01Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_140784366 3.47 ENST00000674533.1
cerebellar degeneration related protein 1
chr18_-_26865689 3.32 ENST00000675739.1
ENST00000383168.9
ENST00000672981.2
ENST00000578776.1
aquaporin 4
chr14_-_24609660 2.90 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
granzyme H
chr18_-_26865732 2.83 ENST00000672188.1
aquaporin 4
chr12_-_54973683 2.81 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
thymocyte expressed, positive selection associated 1
chr1_+_202462730 2.65 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chr1_-_160647037 2.56 ENST00000302035.11
signaling lymphocytic activation molecule family member 1
chr7_-_38300288 2.16 ENST00000390341.2
T cell receptor gamma variable 10 (non-functional)
chr1_-_160646958 2.10 ENST00000538290.2
signaling lymphocytic activation molecule family member 1
chr2_+_190927649 2.04 ENST00000409428.5
ENST00000409215.5
glutaminase
chr17_+_36103819 1.97 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr17_+_36211055 1.95 ENST00000617405.5
ENST00000617416.4
ENST00000613173.4
ENST00000620732.4
ENST00000620098.4
ENST00000620576.4
ENST00000620055.4
ENST00000610565.4
ENST00000620250.1
C-C motif chemokine ligand 4 like 2
chr12_-_54973547 1.88 ENST00000526532.5
ENST00000532757.5
thymocyte expressed, positive selection associated 1
chr5_-_84384871 1.73 ENST00000296591.10
EGF like repeats and discoidin domains 3
chr7_+_80624961 1.71 ENST00000436384.5
CD36 molecule
chr14_-_24634160 1.70 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr5_+_147878703 1.69 ENST00000296694.5
secretoglobin family 3A member 2
chr5_+_119356011 1.69 ENST00000504771.3
ENST00000415806.2
TNF alpha induced protein 8
chr12_-_110920568 1.66 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr11_+_73647549 1.64 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr1_-_203229660 1.63 ENST00000255427.7
ENST00000367229.6
chitinase 1
chr5_+_72179622 1.62 ENST00000504492.1
microtubule associated protein 1B
chr11_-_118212885 1.54 ENST00000524477.5
junction adhesion molecule like
chr8_-_81447428 1.53 ENST00000256103.3
ENST00000519260.1
peripheral myelin protein 2
chr2_-_60550900 1.52 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BAF chromatin remodeling complex subunit BCL11A
chr14_+_22052503 1.46 ENST00000390449.3
T cell receptor alpha variable 21
chr6_-_41286665 1.45 ENST00000589614.5
ENST00000244709.9
ENST00000334475.10
ENST00000591620.1
triggering receptor expressed on myeloid cells 1
chr15_+_91100194 1.39 ENST00000394232.6
synaptic vesicle glycoprotein 2B
chr5_+_36608146 1.38 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr3_+_159069252 1.35 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr3_+_50269140 1.34 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr16_+_30064731 1.29 ENST00000563987.5
aldolase, fructose-bisphosphate A
chr15_+_91099943 1.27 ENST00000545111.6
synaptic vesicle glycoprotein 2B
chrX_+_136169624 1.25 ENST00000394153.6
four and a half LIM domains 1
chr16_-_29745951 1.25 ENST00000329410.4
chromosome 16 open reading frame 54
chr3_+_121593363 1.24 ENST00000338040.6
F-box protein 40
chr3_+_159273235 1.24 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr1_+_149782671 1.23 ENST00000444948.5
ENST00000369168.5
Fc fragment of IgG receptor Ia
chr1_-_160647287 1.19 ENST00000235739.6
signaling lymphocytic activation molecule family member 1
chr19_-_54100792 1.18 ENST00000391761.5
ENST00000356532.7
ENST00000616447.4
ENST00000359649.8
ENST00000358375.8
ENST00000391760.1
ENST00000351806.8
osteoclast associated Ig-like receptor
chr11_+_112961247 1.17 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
neural cell adhesion molecule 1
chr7_-_38249572 1.16 ENST00000436911.6
T cell receptor gamma constant 2
chr9_-_133121228 1.14 ENST00000372050.8
ral guanine nucleotide dissociation stimulator
chr17_-_35880350 1.11 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr17_+_36210924 1.08 ENST00000615418.4
C-C motif chemokine ligand 4 like 2
chrX_+_136169891 1.08 ENST00000449474.5
four and a half LIM domains 1
chr15_+_66453418 1.07 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chrX_+_136169664 1.07 ENST00000456445.5
four and a half LIM domains 1
chrX_+_136169833 1.05 ENST00000628032.2
four and a half LIM domains 1
chr14_-_24634266 1.05 ENST00000382540.5
granzyme B
chr5_-_88823763 1.03 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr4_+_143391506 0.98 ENST00000509992.1
GRB2 associated binding protein 1
chr11_+_112961480 0.97 ENST00000621850.4
neural cell adhesion molecule 1
chr22_+_32043253 0.96 ENST00000266088.9
solute carrier family 5 member 1
chr17_+_38925168 0.96 ENST00000583195.2
long intergenic non-protein coding RNA 672
chr17_-_8867639 0.95 ENST00000619866.5
phosphoinositide-3-kinase regulatory subunit 6
chr20_+_59676661 0.95 ENST00000355648.8
phosphatase and actin regulator 3
chr19_-_7702139 0.95 ENST00000346664.9
Fc fragment of IgE receptor II
chr1_+_192636121 0.94 ENST00000543215.5
ENST00000391995.7
regulator of G protein signaling 13
chr19_-_7702124 0.93 ENST00000597921.6
Fc fragment of IgE receptor II
chr11_+_112961402 0.93 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
neural cell adhesion molecule 1
chr11_-_128587551 0.93 ENST00000392668.8
ETS proto-oncogene 1, transcription factor
chr16_+_30064462 0.93 ENST00000412304.6
aldolase, fructose-bisphosphate A
chr7_-_38265678 0.93 ENST00000443402.6
T cell receptor gamma constant 1
chr2_+_68734861 0.92 ENST00000467265.5
Rho GTPase activating protein 25
chr13_+_48653921 0.92 ENST00000682523.1
cysteinyl leukotriene receptor 2
chr19_-_7700074 0.91 ENST00000593418.1
Fc fragment of IgE receptor II
chr2_-_174597795 0.90 ENST00000679041.1
WAS/WASL interacting protein family member 1
chr2_+_68734773 0.90 ENST00000409202.8
Rho GTPase activating protein 25
chr12_+_57578238 0.90 ENST00000675907.1
kinesin family member 5A
chr6_-_24877262 0.89 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr22_+_44069043 0.89 ENST00000404989.1
parvin beta
chr17_+_34255274 0.88 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2
chr2_-_174597728 0.88 ENST00000409891.5
ENST00000410117.5
WAS/WASL interacting protein family member 1
chr4_-_46993520 0.87 ENST00000264318.4
gamma-aminobutyric acid type A receptor subunit alpha4
chr11_-_59212869 0.85 ENST00000361050.4
macrophage expressed 1
chr7_-_139716980 0.84 ENST00000342645.7
homeodomain interacting protein kinase 2
chr6_+_31572279 0.82 ENST00000418386.3
lymphotoxin alpha
chr1_-_35554930 0.80 ENST00000440579.5
ENST00000494948.1
KIAA0319 like
chr1_+_121087343 0.80 ENST00000616817.4
ENST00000623603.3
ENST00000369384.9
ENST00000369383.8
ENST00000369178.5
Fc fragment of IgG receptor Ib
chr6_-_32853618 0.79 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr6_-_41201128 0.79 ENST00000483722.2
triggering receptor expressed on myeloid cells like 2
chr2_-_201451446 0.78 ENST00000332624.8
ENST00000430254.1
trafficking kinesin protein 2
chr18_+_13277351 0.78 ENST00000679091.1
low density lipoprotein receptor class A domain containing 4
chr18_+_68715191 0.78 ENST00000578970.5
ENST00000582371.5
ENST00000584775.5
coiled-coil domain containing 102B
chr10_-_132307935 0.78 ENST00000298630.8
serine/threonine kinase 32C
chr12_-_54385727 0.78 ENST00000551109.5
ENST00000546970.5
zinc finger protein 385A
chr15_+_24954912 0.76 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr6_-_32853813 0.73 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr7_-_38929550 0.73 ENST00000418457.6
VPS41 subunit of HOPS complex
chr2_-_133568393 0.73 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCK associated protein 5
chr16_+_30064142 0.72 ENST00000562168.5
ENST00000569545.5
aldolase, fructose-bisphosphate A
chr11_+_65314853 0.68 ENST00000279249.3
CDC42 effector protein 2
chrX_-_73214793 0.68 ENST00000373517.4
nucleosome assembly protein 1 like 2
chr16_+_30064274 0.68 ENST00000563060.6
aldolase, fructose-bisphosphate A
chr5_-_116554858 0.67 ENST00000509665.1
semaphorin 6A
chr12_-_118052597 0.67 ENST00000535496.5
WD repeat and SOCS box containing 2
chrX_-_53281524 0.67 ENST00000498281.2
IQ motif and Sec7 domain ArfGEF 2
chr5_-_147081428 0.66 ENST00000394413.7
protein phosphatase 2 regulatory subunit Bbeta
chr3_-_98517096 0.66 ENST00000513873.1
claudin domain containing 1
chr14_+_21918161 0.65 ENST00000390439.2
T cell receptor alpha variable 13-2
chrX_-_50643649 0.65 ENST00000460112.3
shroom family member 4
chr4_+_30720348 0.64 ENST00000361762.3
protocadherin 7
chr20_-_23086316 0.62 ENST00000246006.5
CD93 molecule
chr2_+_106487349 0.61 ENST00000643224.2
ENST00000416057.2
CD8b2 molecule
chr11_-_790062 0.61 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr5_+_127649018 0.60 ENST00000379445.7
cortexin 3
chr5_+_35856883 0.60 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr3_-_179974254 0.59 ENST00000468741.5
peroxisomal biogenesis factor 5 like
chr8_-_142777174 0.57 ENST00000652477.1
ENST00000614491.1
ENST00000613110.4
Ly6/neurotoxin 1
chr4_+_6693870 0.57 ENST00000296370.4
S100 calcium binding protein P
chr2_-_151971750 0.55 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr6_+_26440472 0.54 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr6_+_31571957 0.54 ENST00000454783.5
lymphotoxin alpha
chr3_+_141402322 0.53 ENST00000510338.5
ENST00000504673.5
zinc finger and BTB domain containing 38
chr12_-_46269951 0.52 ENST00000550173.1
solute carrier family 38 member 1
chr16_-_68000549 0.52 ENST00000575510.5
dipeptidase 2
chr12_+_94262521 0.51 ENST00000545312.1
plexin C1
chr12_+_8092881 0.51 ENST00000638334.1
NECAP endocytosis associated 1
chr4_-_120066777 0.50 ENST00000296509.11
mitotic arrest deficient 2 like 1
chr8_-_116874528 0.50 ENST00000517485.5
RAD21 cohesin complex component
chr5_-_74866958 0.49 ENST00000389156.9
family with sequence similarity 169 member A
chr15_+_77015811 0.48 ENST00000559859.5
proline-serine-threonine phosphatase interacting protein 1
chr12_+_8992029 0.47 ENST00000543895.1
killer cell lectin like receptor G1
chr6_+_32854179 0.45 ENST00000374859.3
proteasome 20S subunit beta 9
chr2_+_167248638 0.45 ENST00000295237.10
xin actin binding repeat containing 2
chr11_+_118359572 0.45 ENST00000252108.8
ENST00000431736.6
ubiquitination factor E4A
chr5_+_139273752 0.44 ENST00000509990.5
ENST00000506147.5
ENST00000512107.5
matrin 3
chr19_-_42442938 0.44 ENST00000601181.6
C-X-C motif chemokine ligand 17
chr6_-_33787001 0.43 ENST00000508327.5
ENST00000513701.1
LEM domain nuclear envelope protein 2
chr18_-_55401525 0.42 ENST00000562030.3
ENST00000569012.5
transcription factor 4
chr5_-_141958174 0.42 ENST00000231484.4
protocadherin 12
chr5_+_94618653 0.42 ENST00000265140.10
ENST00000504099.5
SMC5-SMC6 complex localization factor 1
chr2_-_119366757 0.42 ENST00000414534.1
chromosome 2 open reading frame 76
chr13_+_48653711 0.41 ENST00000614739.4
ENST00000617562.4
ENST00000621321.1
ENST00000622559.4
cysteinyl leukotriene receptor 2
chr9_-_10612703 0.41 ENST00000463477.5
protein tyrosine phosphatase receptor type D
chr4_-_48114523 0.41 ENST00000506073.1
TXK tyrosine kinase
chr1_-_100178215 0.41 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
leucine rich repeat containing 39
chr5_-_74866914 0.40 ENST00000513277.5
family with sequence similarity 169 member A
chr12_-_110920710 0.40 ENST00000546404.1
myosin light chain 2
chr8_-_116874746 0.40 ENST00000297338.7
RAD21 cohesin complex component
chr4_+_112860981 0.40 ENST00000671704.1
ankyrin 2
chr2_-_108989206 0.39 ENST00000258443.7
ENST00000409271.5
ENST00000376651.1
ectodysplasin A receptor
chr4_+_112860912 0.39 ENST00000671951.1
ankyrin 2
chr4_+_159241016 0.38 ENST00000644902.1
Rap guanine nucleotide exchange factor 2
chr14_+_55661242 0.38 ENST00000553624.5
kinectin 1
chr17_-_39778213 0.38 ENST00000583368.1
IKAROS family zinc finger 3
chr4_-_46390100 0.37 ENST00000381620.9
gamma-aminobutyric acid type A receptor subunit alpha2
chr5_-_88824266 0.37 ENST00000509373.1
ENST00000636541.1
myocyte enhancer factor 2C
chr22_-_41947087 0.37 ENST00000407253.7
ENST00000215980.10
centromere protein M
chr11_+_8019193 0.36 ENST00000534099.5
TUB bipartite transcription factor
chr5_-_147081462 0.36 ENST00000508267.5
ENST00000504198.5
protein phosphatase 2 regulatory subunit Bbeta
chr1_-_45499931 0.36 ENST00000626657.2
coiled-coil domain containing 163
chr9_-_132079856 0.36 ENST00000651555.1
ENST00000651950.1
ENST00000357028.6
ENST00000474263.1
ENST00000292035.10
mediator complex subunit 27
chr2_+_12716893 0.35 ENST00000381465.2
ENST00000155926.9
tribbles pseudokinase 2
chr4_+_112861053 0.35 ENST00000672221.1
ankyrin 2
chr20_+_43945677 0.34 ENST00000358131.5
TOX high mobility group box family member 2
chr5_-_151686953 0.34 ENST00000538026.5
ENST00000522348.1
ENST00000521569.1
secreted protein acidic and cysteine rich
chr10_-_59362460 0.31 ENST00000422313.6
ENST00000435852.6
ENST00000614220.4
ENST00000618804.5
ENST00000621119.4
family with sequence similarity 13 member C
chr4_-_46390273 0.31 ENST00000515082.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr13_+_50015438 0.30 ENST00000312942.2
potassium channel regulator
chr4_-_46390039 0.30 ENST00000540012.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr1_-_45500040 0.30 ENST00000629482.3
coiled-coil domain containing 163
chr11_-_60952559 0.30 ENST00000538739.2
solute carrier family 15 member 3
chr11_-_72752376 0.29 ENST00000393609.8
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_+_150272772 0.29 ENST00000369098.3
ENST00000369099.8
chromosome 1 open reading frame 54
chr11_-_77820706 0.28 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
remodeling and spacing factor 1
chr2_+_113127588 0.28 ENST00000409930.4
interleukin 1 receptor antagonist
chr3_+_141262614 0.28 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr15_+_78873723 0.28 ENST00000559690.5
ENST00000559158.5
mortality factor 4 like 1
chr20_+_59958422 0.27 ENST00000348616.9
cadherin 26
chr6_+_30557274 0.27 ENST00000376557.3
proline rich 3
chr12_-_124495252 0.27 ENST00000405201.5
nuclear receptor corepressor 2
chr11_+_77821125 0.26 ENST00000526415.5
ENST00000393427.6
ENST00000527134.5
ENST00000304716.12
ENST00000630098.2
adipogenesis associated Mth938 domain containing
chr5_-_151686908 0.26 ENST00000231061.9
secreted protein acidic and cysteine rich
chr22_-_41946688 0.26 ENST00000404067.5
ENST00000402338.5
centromere protein M
chr13_-_51845169 0.26 ENST00000627246.3
ENST00000629372.3
transmembrane protein 272
chr11_+_65333834 0.25 ENST00000528416.6
ENST00000415073.6
ENST00000252268.8
double PHD fingers 2
chr1_-_108192818 0.25 ENST00000370041.4
solute carrier family 25 member 24
chr13_+_50015254 0.24 ENST00000360473.8
potassium channel regulator
chr2_-_229921903 0.23 ENST00000389045.7
ENST00000409677.5
thyroid hormone receptor interactor 12
chr14_+_38207893 0.22 ENST00000267377.3
somatostatin receptor 1
chr2_-_229921316 0.22 ENST00000428959.5
ENST00000675423.1
thyroid hormone receptor interactor 12
chr3_-_49813880 0.22 ENST00000333486.4
ubiquitin like modifier activating enzyme 7
chr13_-_29586788 0.22 ENST00000450494.1
solute carrier family 7 member 1
chr11_+_63888515 0.21 ENST00000509502.6
ENST00000512060.1
microtubule affinity regulating kinase 2
chr1_-_190477854 0.21 ENST00000367462.5
BMP/retinoic acid inducible neural specific 3
chr12_-_81759307 0.21 ENST00000547623.5
ENST00000549396.6
PTPRF interacting protein alpha 2
chr1_+_77918128 0.20 ENST00000342754.5
nexilin F-actin binding protein
chr1_+_66330711 0.20 ENST00000528771.5
phosphodiesterase 4B
chr14_+_55661272 0.20 ENST00000555573.5
kinectin 1
chr2_+_131011683 0.19 ENST00000355771.7
Rho guanine nucleotide exchange factor 4
chr10_-_59362584 0.19 ENST00000618427.4
ENST00000611933.4
family with sequence similarity 13 member C
chr8_+_122781621 0.19 ENST00000314393.6
zinc fingers and homeoboxes 2
chr3_+_130443484 0.18 ENST00000512482.1
collagen type VI alpha 5 chain
chr12_-_81758641 0.18 ENST00000552948.5
ENST00000548586.5
PTPRF interacting protein alpha 2
chr12_+_56041893 0.18 ENST00000552361.1
ENST00000646449.2
ribosomal protein S26
chr9_-_7799752 0.17 ENST00000358227.5
distal membrane arm assembly complex 1
chr7_-_77199808 0.17 ENST00000248598.6
fibrinogen like 2
chr1_+_213989691 0.17 ENST00000607425.1
prospero homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.8 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.8 4.7 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.6 3.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.5 4.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.5 1.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 2.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 0.9 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.3 2.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 1.7 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 1.5 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 0.7 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.2 1.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 1.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 1.5 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 3.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.5 GO:0035696 monocyte extravasation(GO:0035696)
0.2 2.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 6.2 GO:0006833 water transport(GO:0006833)
0.1 0.9 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 1.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.8 GO:0030578 PML body organization(GO:0030578)
0.1 1.7 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.6 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.0 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 1.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.8 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 1.1 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 0.6 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.9 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.9 GO:2001023 regulation of response to drug(GO:2001023)
0.1 0.6 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 1.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.2 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 4.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 2.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 5.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:1904863 regulation of beta-catenin-TCF complex assembly(GO:1904863) negative regulation of beta-catenin-TCF complex assembly(GO:1904864)
0.0 0.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 1.0 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 1.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.5 GO:0042825 TAP complex(GO:0042825)
0.1 2.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 0.9 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.9 GO:0060171 stereocilium membrane(GO:0060171)
0.1 6.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 2.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 4.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.0 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.9 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.7 GO:0001772 immunological synapse(GO:0001772)
0.0 18.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.8 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 6.2 GO:0015250 water channel activity(GO:0015250)
0.3 2.8 GO:0019863 IgE binding(GO:0019863)
0.3 3.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 2.0 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 1.5 GO:0046979 MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.2 1.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 1.2 GO:0019864 IgG binding(GO:0019864)
0.1 1.9 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 2.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 7.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.5 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 3.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 4.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 4.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 4.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 4.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 3.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase