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Illumina Body Map 2 (GSE30611)

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Results for STAT6

Z-value: 1.04

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
STAT6
ENSG00000166888.12 signal transducer and activator of transcription 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg38_v1_chr12_-_57111338_57111433-0.154.2e-01Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_140784366 3.47 ENST00000674533.1
CDR1
cerebellar degeneration related protein 1
chr18_-_26865689 3.32 ENST00000675739.1
ENST00000383168.9
ENST00000672981.2
ENST00000578776.1
AQP4
aquaporin 4
chr14_-_24609660 2.90 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
GZMH
granzyme H
chr18_-_26865732 2.83 ENST00000672188.1
AQP4
aquaporin 4
chr12_-_54973683 2.81 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
TESPA1
thymocyte expressed, positive selection associated 1
chr1_+_202462730 2.65 ENST00000290419.9
ENST00000491336.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr1_-_160647037 2.56 ENST00000302035.11
SLAMF1
signaling lymphocytic activation molecule family member 1
chr7_-_38300288 2.16 ENST00000390341.2
TRGV10
T cell receptor gamma variable 10 (non-functional)
chr1_-_160646958 2.10 ENST00000538290.2
SLAMF1
signaling lymphocytic activation molecule family member 1
chr2_+_190927649 2.04 ENST00000409428.5
ENST00000409215.5
GLS
glutaminase
chr17_+_36103819 1.97 ENST00000615863.2
ENST00000621626.1
CCL4
C-C motif chemokine ligand 4
chr17_+_36211055 1.95 ENST00000617405.5
ENST00000617416.4
ENST00000613173.4
ENST00000620732.4
ENST00000620098.4
ENST00000620576.4
ENST00000620055.4
ENST00000610565.4
ENST00000620250.1
CCL4L2
C-C motif chemokine ligand 4 like 2
chr12_-_54973547 1.88 ENST00000526532.5
ENST00000532757.5
TESPA1
thymocyte expressed, positive selection associated 1
chr5_-_84384871 1.73 ENST00000296591.10
EDIL3
EGF like repeats and discoidin domains 3
chr7_+_80624961 1.71 ENST00000436384.5
CD36
CD36 molecule
chr14_-_24634160 1.70 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
GZMB
granzyme B
chr5_+_147878703 1.69 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr5_+_119356011 1.69 ENST00000504771.3
ENST00000415806.2
TNFAIP8
TNF alpha induced protein 8
chr12_-_110920568 1.66 ENST00000548438.1
ENST00000228841.15
MYL2
myosin light chain 2
chr11_+_73647549 1.64 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
PLEKHB1
pleckstrin homology domain containing B1
chr1_-_203229660 1.63 ENST00000255427.7
ENST00000367229.6
CHIT1
chitinase 1
chr5_+_72179622 1.62 ENST00000504492.1
MAP1B
microtubule associated protein 1B
chr11_-_118212885 1.54 ENST00000524477.5
JAML
junction adhesion molecule like
chr8_-_81447428 1.53 ENST00000256103.3
ENST00000519260.1
PMP2
peripheral myelin protein 2
chr2_-_60550900 1.52 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr14_+_22052503 1.46 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr6_-_41286665 1.45 ENST00000589614.5
ENST00000244709.9
ENST00000334475.10
ENST00000591620.1
TREM1
triggering receptor expressed on myeloid cells 1
chr15_+_91100194 1.39 ENST00000394232.6
SV2B
synaptic vesicle glycoprotein 2B
chr5_+_36608146 1.38 ENST00000381918.4
ENST00000513646.1
SLC1A3
solute carrier family 1 member 3
chr3_+_159069252 1.35 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr3_+_50269140 1.34 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
SEMA3B
semaphorin 3B
chr16_+_30064731 1.29 ENST00000563987.5
ALDOA
aldolase, fructose-bisphosphate A
chr15_+_91099943 1.27 ENST00000545111.6
SV2B
synaptic vesicle glycoprotein 2B
chrX_+_136169624 1.25 ENST00000394153.6
FHL1
four and a half LIM domains 1
chr16_-_29745951 1.25 ENST00000329410.4
C16orf54
chromosome 16 open reading frame 54
chr3_+_121593363 1.24 ENST00000338040.6
FBXO40
F-box protein 40
chr3_+_159273235 1.24 ENST00000638749.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_+_149782671 1.23 ENST00000444948.5
ENST00000369168.5
FCGR1A
Fc fragment of IgG receptor Ia
chr1_-_160647287 1.19 ENST00000235739.6
SLAMF1
signaling lymphocytic activation molecule family member 1
chr19_-_54100792 1.18 ENST00000391761.5
ENST00000356532.7
ENST00000616447.4
ENST00000359649.8
ENST00000358375.8
ENST00000391760.1
ENST00000351806.8
OSCAR
osteoclast associated Ig-like receptor
chr11_+_112961247 1.17 ENST00000621518.4
ENST00000618266.4
ENST00000615112.4
ENST00000615285.4
ENST00000619839.4
ENST00000401611.6
ENST00000621128.4
NCAM1
neural cell adhesion molecule 1
chr7_-_38249572 1.16 ENST00000436911.6
TRGC2
T cell receptor gamma constant 2
chr9_-_133121228 1.14 ENST00000372050.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr17_-_35880350 1.11 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
CCL5
C-C motif chemokine ligand 5
chr17_+_36210924 1.08 ENST00000615418.4
CCL4L2
C-C motif chemokine ligand 4 like 2
chrX_+_136169891 1.08 ENST00000449474.5
FHL1
four and a half LIM domains 1
chr15_+_66453418 1.07 ENST00000566326.1
MAP2K1
mitogen-activated protein kinase kinase 1
chrX_+_136169664 1.07 ENST00000456445.5
FHL1
four and a half LIM domains 1
chrX_+_136169833 1.05 ENST00000628032.2
FHL1
four and a half LIM domains 1
chr14_-_24634266 1.05 ENST00000382540.5
GZMB
granzyme B
chr5_-_88823763 1.03 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
MEF2C
myocyte enhancer factor 2C
chr4_+_143391506 0.98 ENST00000509992.1
GAB1
GRB2 associated binding protein 1
chr11_+_112961480 0.97 ENST00000621850.4
NCAM1
neural cell adhesion molecule 1
chr22_+_32043253 0.96 ENST00000266088.9
SLC5A1
solute carrier family 5 member 1
chr17_+_38925168 0.96 ENST00000583195.2
LINC00672
long intergenic non-protein coding RNA 672
chr17_-_8867639 0.95 ENST00000619866.5
PIK3R6
phosphoinositide-3-kinase regulatory subunit 6
chr20_+_59676661 0.95 ENST00000355648.8
PHACTR3
phosphatase and actin regulator 3
chr19_-_7702139 0.95 ENST00000346664.9
FCER2
Fc fragment of IgE receptor II
chr1_+_192636121 0.94 ENST00000543215.5
ENST00000391995.7
RGS13
regulator of G protein signaling 13
chr19_-_7702124 0.93 ENST00000597921.6
FCER2
Fc fragment of IgE receptor II
chr11_+_112961402 0.93 ENST00000613217.4
ENST00000316851.12
ENST00000620046.4
ENST00000531044.5
ENST00000529356.5
NCAM1
neural cell adhesion molecule 1
chr11_-_128587551 0.93 ENST00000392668.8
ETS1
ETS proto-oncogene 1, transcription factor
chr16_+_30064462 0.93 ENST00000412304.6
ALDOA
aldolase, fructose-bisphosphate A
chr7_-_38265678 0.93 ENST00000443402.6
TRGC1
T cell receptor gamma constant 1
chr2_+_68734861 0.92 ENST00000467265.5
ARHGAP25
Rho GTPase activating protein 25
chr13_+_48653921 0.92 ENST00000682523.1
CYSLTR2
cysteinyl leukotriene receptor 2
chr19_-_7700074 0.91 ENST00000593418.1
FCER2
Fc fragment of IgE receptor II
chr2_-_174597795 0.90 ENST00000679041.1
WIPF1
WAS/WASL interacting protein family member 1
chr2_+_68734773 0.90 ENST00000409202.8
ARHGAP25
Rho GTPase activating protein 25
chr12_+_57578238 0.90 ENST00000675907.1
KIF5A
kinesin family member 5A
chr6_-_24877262 0.89 ENST00000378023.8
ENST00000540914.5
RIPOR2
RHO family interacting cell polarization regulator 2
chr22_+_44069043 0.89 ENST00000404989.1
PARVB
parvin beta
chr17_+_34255274 0.88 ENST00000580907.5
ENST00000225831.4
CCL2
C-C motif chemokine ligand 2
chr2_-_174597728 0.88 ENST00000409891.5
ENST00000410117.5
WIPF1
WAS/WASL interacting protein family member 1
chr4_-_46993520 0.87 ENST00000264318.4
GABRA4
gamma-aminobutyric acid type A receptor subunit alpha4
chr11_-_59212869 0.85 ENST00000361050.4
MPEG1
macrophage expressed 1
chr7_-_139716980 0.84 ENST00000342645.7
HIPK2
homeodomain interacting protein kinase 2
chr6_+_31572279 0.82 ENST00000418386.3
LTA
lymphotoxin alpha
chr1_-_35554930 0.80 ENST00000440579.5
ENST00000494948.1
KIAA0319L
KIAA0319 like
chr1_+_121087343 0.80 ENST00000616817.4
ENST00000623603.3
ENST00000369384.9
ENST00000369383.8
ENST00000369178.5
FCGR1B
Fc fragment of IgG receptor Ib
chr6_-_32853618 0.79 ENST00000354258.5
TAP1
transporter 1, ATP binding cassette subfamily B member
chr6_-_41201128 0.79 ENST00000483722.2
TREML2
triggering receptor expressed on myeloid cells like 2
chr2_-_201451446 0.78 ENST00000332624.8
ENST00000430254.1
TRAK2
trafficking kinesin protein 2
chr18_+_13277351 0.78 ENST00000679091.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr18_+_68715191 0.78 ENST00000578970.5
ENST00000582371.5
ENST00000584775.5
CCDC102B
coiled-coil domain containing 102B
chr10_-_132307935 0.78 ENST00000298630.8
STK32C
serine/threonine kinase 32C
chr12_-_54385727 0.78 ENST00000551109.5
ENST00000546970.5
ZNF385A
zinc finger protein 385A
chr15_+_24954912 0.76 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
SNRPN
SNURF
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr6_-_32853813 0.73 ENST00000643049.2
TAP1
transporter 1, ATP binding cassette subfamily B member
chr7_-_38929550 0.73 ENST00000418457.6
VPS41
VPS41 subunit of HOPS complex
chr2_-_133568393 0.73 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCKAP5
NCK associated protein 5
chr16_+_30064142 0.72 ENST00000562168.5
ENST00000569545.5
ALDOA
aldolase, fructose-bisphosphate A
chr11_+_65314853 0.68 ENST00000279249.3
CDC42EP2
CDC42 effector protein 2
chrX_-_73214793 0.68 ENST00000373517.4
NAP1L2
nucleosome assembly protein 1 like 2
chr16_+_30064274 0.68 ENST00000563060.6
ALDOA
aldolase, fructose-bisphosphate A
chr5_-_116554858 0.67 ENST00000509665.1
SEMA6A
semaphorin 6A
chr12_-_118052597 0.67 ENST00000535496.5
WSB2
WD repeat and SOCS box containing 2
chrX_-_53281524 0.67 ENST00000498281.2
IQSEC2
IQ motif and Sec7 domain ArfGEF 2
chr5_-_147081428 0.66 ENST00000394413.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr3_-_98517096 0.66 ENST00000513873.1
CLDND1
claudin domain containing 1
chr14_+_21918161 0.65 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chrX_-_50643649 0.65 ENST00000460112.3
SHROOM4
shroom family member 4
chr4_+_30720348 0.64 ENST00000361762.3
PCDH7
protocadherin 7
chr20_-_23086316 0.62 ENST00000246006.5
CD93
CD93 molecule
chr2_+_106487349 0.61 ENST00000643224.2
ENST00000416057.2
CD8B2
CD8b2 molecule
chr11_-_790062 0.61 ENST00000330106.5
CEND1
cell cycle exit and neuronal differentiation 1
chr5_+_127649018 0.60 ENST00000379445.7
CTXN3
cortexin 3
chr5_+_35856883 0.60 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr3_-_179974254 0.59 ENST00000468741.5
PEX5L
peroxisomal biogenesis factor 5 like
chr8_-_142777174 0.57 ENST00000652477.1
ENST00000614491.1
ENST00000613110.4
LYNX1
Ly6/neurotoxin 1
chr4_+_6693870 0.57 ENST00000296370.4
S100P
S100 calcium binding protein P
chr2_-_151971750 0.55 ENST00000636598.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr6_+_26440472 0.54 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
BTN3A3
butyrophilin subfamily 3 member A3
chr6_+_31571957 0.54 ENST00000454783.5
LTA
lymphotoxin alpha
chr3_+_141402322 0.53 ENST00000510338.5
ENST00000504673.5
ZBTB38
zinc finger and BTB domain containing 38
chr12_-_46269951 0.52 ENST00000550173.1
SLC38A1
solute carrier family 38 member 1
chr16_-_68000549 0.52 ENST00000575510.5
DPEP2
dipeptidase 2
chr12_+_94262521 0.51 ENST00000545312.1
PLXNC1
plexin C1
chr12_+_8092881 0.51 ENST00000638334.1
NECAP1
NECAP endocytosis associated 1
chr4_-_120066777 0.50 ENST00000296509.11
MAD2L1
mitotic arrest deficient 2 like 1
chr8_-_116874528 0.50 ENST00000517485.5
RAD21
RAD21 cohesin complex component
chr5_-_74866958 0.49 ENST00000389156.9
FAM169A
family with sequence similarity 169 member A
chr15_+_77015811 0.48 ENST00000559859.5
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr12_+_8992029 0.47 ENST00000543895.1
KLRG1
killer cell lectin like receptor G1
chr6_+_32854179 0.45 ENST00000374859.3
PSMB9
proteasome 20S subunit beta 9
chr2_+_167248638 0.45 ENST00000295237.10
XIRP2
xin actin binding repeat containing 2
chr11_+_118359572 0.45 ENST00000252108.8
ENST00000431736.6
UBE4A
ubiquitination factor E4A
chr5_+_139273752 0.44 ENST00000509990.5
ENST00000506147.5
ENST00000512107.5
MATR3
matrin 3
chr19_-_42442938 0.44 ENST00000601181.6
CXCL17
C-X-C motif chemokine ligand 17
chr6_-_33787001 0.43 ENST00000508327.5
ENST00000513701.1
LEMD2
LEM domain nuclear envelope protein 2
chr18_-_55401525 0.42 ENST00000562030.3
ENST00000569012.5
TCF4
transcription factor 4
chr5_-_141958174 0.42 ENST00000231484.4
PCDH12
protocadherin 12
chr5_+_94618653 0.42 ENST00000265140.10
ENST00000504099.5
SLF1
SMC5-SMC6 complex localization factor 1
chr2_-_119366757 0.42 ENST00000414534.1
C2orf76
chromosome 2 open reading frame 76
chr13_+_48653711 0.41 ENST00000614739.4
ENST00000617562.4
ENST00000621321.1
ENST00000622559.4
CYSLTR2
cysteinyl leukotriene receptor 2
chr9_-_10612703 0.41 ENST00000463477.5
PTPRD
protein tyrosine phosphatase receptor type D
chr4_-_48114523 0.41 ENST00000506073.1
TXK
TXK tyrosine kinase
chr1_-_100178215 0.41 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
LRRC39
leucine rich repeat containing 39
chr5_-_74866914 0.40 ENST00000513277.5
FAM169A
family with sequence similarity 169 member A
chr12_-_110920710 0.40 ENST00000546404.1
MYL2
myosin light chain 2
chr8_-_116874746 0.40 ENST00000297338.7
RAD21
RAD21 cohesin complex component
chr4_+_112860981 0.40 ENST00000671704.1
ANK2
ankyrin 2
chr2_-_108989206 0.39 ENST00000258443.7
ENST00000409271.5
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr4_+_112860912 0.39 ENST00000671951.1
ANK2
ankyrin 2
chr4_+_159241016 0.38 ENST00000644902.1
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr14_+_55661242 0.38 ENST00000553624.5
KTN1
kinectin 1
chr17_-_39778213 0.38 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3
chr4_-_46390100 0.37 ENST00000381620.9
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr5_-_88824266 0.37 ENST00000509373.1
ENST00000636541.1
MEF2C
myocyte enhancer factor 2C
chr22_-_41947087 0.37 ENST00000407253.7
ENST00000215980.10
CENPM
centromere protein M
chr11_+_8019193 0.36 ENST00000534099.5
TUB
TUB bipartite transcription factor
chr5_-_147081462 0.36 ENST00000508267.5
ENST00000504198.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr1_-_45499931 0.36 ENST00000626657.2
CCDC163
coiled-coil domain containing 163
chr9_-_132079856 0.36 ENST00000651555.1
ENST00000651950.1
ENST00000357028.6
ENST00000474263.1
ENST00000292035.10
MED27
mediator complex subunit 27
chr2_+_12716893 0.35 ENST00000381465.2
ENST00000155926.9
TRIB2
tribbles pseudokinase 2
chr4_+_112861053 0.35 ENST00000672221.1
ANK2
ankyrin 2
chr20_+_43945677 0.34 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr5_-_151686953 0.34 ENST00000538026.5
ENST00000522348.1
ENST00000521569.1
SPARC
secreted protein acidic and cysteine rich
chr10_-_59362460 0.31 ENST00000422313.6
ENST00000435852.6
ENST00000614220.4
ENST00000618804.5
ENST00000621119.4
FAM13C
family with sequence similarity 13 member C
chr4_-_46390273 0.31 ENST00000515082.5
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr13_+_50015438 0.30 ENST00000312942.2
KCNRG
potassium channel regulator
chr4_-_46390039 0.30 ENST00000540012.5
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr1_-_45500040 0.30 ENST00000629482.3
CCDC163
coiled-coil domain containing 163
chr11_-_60952559 0.30 ENST00000538739.2
SLC15A3
solute carrier family 15 member 3
chr11_-_72752376 0.29 ENST00000393609.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_+_150272772 0.29 ENST00000369098.3
ENST00000369099.8
C1orf54
chromosome 1 open reading frame 54
chr11_-_77820706 0.28 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
RSF1
remodeling and spacing factor 1
chr2_+_113127588 0.28 ENST00000409930.4
IL1RN
interleukin 1 receptor antagonist
chr3_+_141262614 0.28 ENST00000504264.5
PXYLP1
2-phosphoxylose phosphatase 1
chr15_+_78873723 0.28 ENST00000559690.5
ENST00000559158.5
MORF4L1
mortality factor 4 like 1
chr20_+_59958422 0.27 ENST00000348616.9
CDH26
cadherin 26
chr6_+_30557274 0.27 ENST00000376557.3
PRR3
proline rich 3
chr12_-_124495252 0.27 ENST00000405201.5
NCOR2
nuclear receptor corepressor 2
chr11_+_77821125 0.26 ENST00000526415.5
ENST00000393427.6
ENST00000527134.5
ENST00000304716.12
ENST00000630098.2
AAMDC
adipogenesis associated Mth938 domain containing
chr5_-_151686908 0.26 ENST00000231061.9
SPARC
secreted protein acidic and cysteine rich
chr22_-_41946688 0.26 ENST00000404067.5
ENST00000402338.5
CENPM
centromere protein M
chr13_-_51845169 0.26 ENST00000627246.3
ENST00000629372.3
TMEM272
transmembrane protein 272
chr11_+_65333834 0.25 ENST00000528416.6
ENST00000415073.6
ENST00000252268.8
DPF2
double PHD fingers 2
chr1_-_108192818 0.25 ENST00000370041.4
SLC25A24
solute carrier family 25 member 24
chr13_+_50015254 0.24 ENST00000360473.8
KCNRG
potassium channel regulator
chr2_-_229921903 0.23 ENST00000389045.7
ENST00000409677.5
TRIP12
thyroid hormone receptor interactor 12
chr14_+_38207893 0.22 ENST00000267377.3
SSTR1
somatostatin receptor 1
chr2_-_229921316 0.22 ENST00000428959.5
ENST00000675423.1
TRIP12
thyroid hormone receptor interactor 12
chr3_-_49813880 0.22 ENST00000333486.4
UBA7
ubiquitin like modifier activating enzyme 7
chr13_-_29586788 0.22 ENST00000450494.1
SLC7A1
solute carrier family 7 member 1
chr11_+_63888515 0.21 ENST00000509502.6
ENST00000512060.1
MARK2
microtubule affinity regulating kinase 2
chr1_-_190477854 0.21 ENST00000367462.5
BRINP3
BMP/retinoic acid inducible neural specific 3
chr12_-_81759307 0.21 ENST00000547623.5
ENST00000549396.6
PPFIA2
PTPRF interacting protein alpha 2
chr1_+_77918128 0.20 ENST00000342754.5
NEXN
nexilin F-actin binding protein
chr1_+_66330711 0.20 ENST00000528771.5
PDE4B
phosphodiesterase 4B
chr14_+_55661272 0.20 ENST00000555573.5
KTN1
kinectin 1
chr2_+_131011683 0.19 ENST00000355771.7
ARHGEF4
Rho guanine nucleotide exchange factor 4
chr10_-_59362584 0.19 ENST00000618427.4
ENST00000611933.4
FAM13C
family with sequence similarity 13 member C
chr8_+_122781621 0.19 ENST00000314393.6
ZHX2
zinc fingers and homeoboxes 2
chr3_+_130443484 0.18 ENST00000512482.1
COL6A5
collagen type VI alpha 5 chain
chr12_-_81758641 0.18 ENST00000552948.5
ENST00000548586.5
PPFIA2
PTPRF interacting protein alpha 2
chr12_+_56041893 0.18 ENST00000552361.1
ENST00000646449.2
RPS26
ribosomal protein S26
chr9_-_7799752 0.17 ENST00000358227.5
DMAC1
distal membrane arm assembly complex 1
chr7_-_77199808 0.17 ENST00000248598.6
FGL2
fibrinogen like 2
chr1_+_213989691 0.17 ENST00000607425.1
PROX1
prospero homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.8 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.8 4.7 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.6 3.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.5 4.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.5 1.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 2.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 0.9 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.3 2.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 1.7 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 1.5 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 0.7 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.2 1.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 1.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 1.5 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 3.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.5 GO:0035696 monocyte extravasation(GO:0035696)
0.2 2.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 6.2 GO:0006833 water transport(GO:0006833)
0.1 0.9 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 1.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.8 GO:0030578 PML body organization(GO:0030578)
0.1 1.7 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.6 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.0 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 1.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.8 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 1.1 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 0.6 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.9 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.9 GO:2001023 regulation of response to drug(GO:2001023)
0.1 0.6 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 1.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.2 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 4.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 2.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 5.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:1904863 regulation of beta-catenin-TCF complex assembly(GO:1904863) negative regulation of beta-catenin-TCF complex assembly(GO:1904864)
0.0 0.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 1.0 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 1.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.5 GO:0042825 TAP complex(GO:0042825)
0.1 2.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 0.9 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.9 GO:0060171 stereocilium membrane(GO:0060171)
0.1 6.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 2.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 4.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.0 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.9 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.7 GO:0001772 immunological synapse(GO:0001772)
0.0 18.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.8 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 6.2 GO:0015250 water channel activity(GO:0015250)
0.3 2.8 GO:0019863 IgE binding(GO:0019863)
0.3 3.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 2.0 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 1.5 GO:0046979 MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.2 1.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 1.2 GO:0019864 IgG binding(GO:0019864)
0.1 1.9 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 2.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 7.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.5 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 3.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 4.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 4.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 4.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 4.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 3.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase