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Illumina Body Map 2 (GSE30611)
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Results for T
Z-value: 0.82
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Transcription factors associated with T
| Gene Symbol | Gene ID | Gene Info |
|---|
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBXT | hg38_v1_chr6_-_166168700_166168727 | 0.13 | 4.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_55024250 Show fit | 3.01 |
ENST00000231009.3
|
granzyme K |
|
| chr1_-_19979607 Show fit | 2.85 |
ENST00000400520.8
ENST00000482011.2 ENST00000649436.1 |
phospholipase A2 group IIA |
|
| chr2_-_218166951 Show fit | 2.53 |
ENST00000295683.3
|
C-X-C motif chemokine receptor 1 |
|
| chr14_-_106557465 Show fit | 2.52 |
ENST00000390625.3
|
immunoglobulin heavy variable 3-49 |
|
| chr12_+_53985138 Show fit | 2.50 |
ENST00000303460.5
|
homeobox C10 |
|
| chr17_+_36103819 Show fit | 2.35 |
ENST00000615863.2
ENST00000621626.1 |
C-C motif chemokine ligand 4 |
|
| chr1_-_205321737 Show fit | 2.00 |
ENST00000367157.6
|
NUAK family kinase 2 |
|
| chr20_+_58150896 Show fit | 1.84 |
ENST00000371168.4
|
chromosome 20 open reading frame 85 |
|
| chr21_+_29130630 Show fit | 1.82 |
ENST00000399926.5
ENST00000399928.6 |
MAP3K7 C-terminal like |
|
| chr16_-_88651015 Show fit | 1.69 |
ENST00000568278.1
ENST00000569359.5 ENST00000567174.5 ENST00000261623.8 |
cytochrome b-245 alpha chain |
Network of associatons between targets according to the STRING database.
First level regulatory network of T
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.0 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 0.2 | 3.9 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.0 | 3.7 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 3.3 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.3 | 3.1 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.1 | 2.9 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 2.8 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.4 | 2.5 | GO:0038112 | interleukin-8-mediated signaling pathway(GO:0038112) |
| 0.0 | 2.5 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.4 | 2.3 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.4 | 3.5 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.3 | 3.1 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.0 | 2.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 2.0 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 1.7 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.2 | 1.6 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 1.6 | GO:0097208 | alveolar lamellar body(GO:0097208) multivesicular body lumen(GO:0097486) |
| 0.0 | 1.6 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 1.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.0 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.1 | 3.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 3.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 3.1 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 2.9 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.2 | 2.8 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.4 | 2.5 | GO:0004918 | interleukin-8 receptor activity(GO:0004918) |
| 0.5 | 2.3 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.0 | 2.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.3 | 2.0 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.0 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.1 | 3.1 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 2.8 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.0 | 2.8 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 2.5 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 2.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 2.3 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 2.0 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.3 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.1 | 1.1 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.3 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 4.0 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 3.1 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.2 | 2.9 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 2.8 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 2.0 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 1.7 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 1.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 1.4 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |