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Illumina Body Map 2 (GSE30611)

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Results for TBP

Z-value: 3.31

Motif logo

Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
ENSG00000112592.14 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg38_v1_chr6_+_170554333_170554396-0.441.1e-02Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_159587817 23.18 ENST00000255040.3
amyloid P component, serum
chr11_+_18266254 21.39 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr11_-_18248632 18.55 ENST00000524555.3
ENST00000528349.5
ENST00000526900.1
ENST00000529528.5
ENST00000414546.6
SAA2-SAA4 readthrough
serum amyloid A2
chr11_-_18248662 18.26 ENST00000256733.9
serum amyloid A2
chr10_-_93601228 16.04 ENST00000371464.8
retinol binding protein 4
chr3_+_149474688 11.58 ENST00000305354.5
ENST00000465758.1
transmembrane 4 L six family member 4
chr17_-_36017953 11.31 ENST00000612516.4
ENST00000615050.2
C-C motif chemokine ligand 23
chr16_+_82035245 11.21 ENST00000199936.9
hydroxysteroid 17-beta dehydrogenase 2
chr11_-_5227063 11.15 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr1_-_159714581 10.12 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr3_-_165837412 9.87 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr16_-_56668034 9.34 ENST00000569500.5
ENST00000379811.4
ENST00000444837.6
metallothionein 1G
chr2_-_150487658 8.84 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr2_-_21044063 8.67 ENST00000233242.5
apolipoprotein B
chr7_+_143132069 8.47 ENST00000291009.4
prolactin induced protein
chr10_+_7703300 8.15 ENST00000358415.9
inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_43942627 8.08 ENST00000617612.3
chromosome 11 open reading frame 96
chr15_+_45430579 8.08 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr1_-_58577244 8.04 ENST00000371225.4
tumor associated calcium signal transducer 2
chr11_-_5234475 8.02 ENST00000292901.7
ENST00000650601.1
ENST00000417377.1
hemoglobin subunit delta
chr5_-_42811884 8.02 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr10_+_94938649 7.98 ENST00000461906.1
ENST00000260682.8
cytochrome P450 family 2 subfamily C member 9
chr8_-_6877928 7.86 ENST00000297439.4
defensin beta 1
chr10_+_7703340 7.67 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr10_-_95069489 7.62 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
cytochrome P450 family 2 subfamily C member 8
chr1_-_161223559 7.42 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
apolipoprotein A2
chr5_+_79111802 7.25 ENST00000524080.1
ENST00000274353.10
betaine--homocysteine S-methyltransferase
chr20_-_45254556 7.15 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr4_-_74099187 7.13 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr1_-_169734064 7.07 ENST00000333360.12
selectin E
chr13_+_53028806 7.04 ENST00000219022.3
olfactomedin 4
chr20_+_31605280 7.03 ENST00000376105.4
ENST00000376112.4
inhibitor of DNA binding 1, HLH protein
chr19_+_35282520 6.86 ENST00000222304.5
hepcidin antimicrobial peptide
chr10_+_87659839 6.69 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr19_+_8364146 6.67 ENST00000301455.7
ENST00000393962.6
angiopoietin like 4
chr19_-_6720641 6.57 ENST00000245907.11
complement C3
chr9_+_128149447 6.55 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr16_+_82034978 6.50 ENST00000563491.5
hydroxysteroid 17-beta dehydrogenase 2
chr3_+_148865288 6.40 ENST00000296046.4
carboxypeptidase A3
chr1_-_230714112 6.33 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
angiotensinogen
chr19_-_35757009 6.29 ENST00000587965.1
ENST00000004982.6
heat shock protein family B (small) member 6
chr12_-_11310420 6.27 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr21_-_42315336 6.24 ENST00000398431.2
ENST00000518498.3
trefoil factor 3
chr11_-_116823293 6.18 ENST00000357780.5
apolipoprotein A4
chr12_-_21604840 6.14 ENST00000261195.3
glycogen synthase 2
chr1_-_8026283 6.07 ENST00000474874.5
ENST00000469499.5
ENST00000377482.10
ERBB receptor feedback inhibitor 1
chr9_+_134880806 6.02 ENST00000291744.11
ENST00000350339.3
ficolin 2
chrX_-_106038721 6.00 ENST00000372563.2
serpin family A member 7
chr16_+_82035267 5.91 ENST00000566213.1
hydroxysteroid 17-beta dehydrogenase 2
chr17_-_50468871 5.85 ENST00000508540.6
ENST00000258969.4
chondroadherin
chr6_-_41747390 5.81 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
progastricsin
chr5_+_42548043 5.72 ENST00000618088.4
ENST00000612382.4
growth hormone receptor
chr8_-_7018295 5.52 ENST00000327857.7
defensin alpha 3
chr16_+_56625775 5.48 ENST00000330439.7
ENST00000568293.1
metallothionein 1E
chr5_+_132873660 5.38 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr12_-_11269696 5.23 ENST00000381842.7
proline rich protein BstNI subfamily 3
chr1_-_168729187 5.22 ENST00000367817.4
dermatopontin
chr9_-_101435760 5.20 ENST00000647789.2
ENST00000616752.1
aldolase, fructose-bisphosphate B
chr18_-_63661884 5.19 ENST00000332821.8
ENST00000283752.10
serpin family B member 3
chr19_+_45864318 5.15 ENST00000302177.3
forkhead box A3
chr19_-_40882226 5.14 ENST00000301146.9
cytochrome P450 family 2 subfamily A member 7
chr11_-_116837586 5.05 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
apolipoprotein A1
chr3_-_142889156 5.02 ENST00000648195.1
procollagen C-endopeptidase enhancer 2
chr16_+_56669807 4.99 ENST00000332374.5
metallothionein 1H
chr17_-_41518878 4.94 ENST00000254043.8
keratin 15
chr15_-_62165274 4.92 ENST00000380392.4
C2 calcium dependent domain containing 4B
chr4_-_74038681 4.85 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr1_-_161223408 4.80 ENST00000491350.1
apolipoprotein A2
chr1_+_31413187 4.79 ENST00000373709.8
serine incorporator 2
chr11_-_102780620 4.76 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr20_+_33235987 4.63 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPI fold containing family A member 1
chr17_+_34285734 4.58 ENST00000305869.4
C-C motif chemokine ligand 11
chr17_-_50201618 4.54 ENST00000225964.10
collagen type I alpha 1 chain
chr3_+_194136138 4.52 ENST00000232424.4
hes family bHLH transcription factor 1
chr3_+_142623386 4.43 ENST00000337777.7
ENST00000497199.5
plastin 1
chr1_+_85580751 4.41 ENST00000451137.7
cellular communication network factor 1
chr17_+_34356472 4.34 ENST00000225844.7
C-C motif chemokine ligand 13
chr20_+_3071618 4.29 ENST00000217386.2
oxytocin/neurophysin I prepropeptide
chr12_-_91146195 4.27 ENST00000548218.1
decorin
chr12_-_11269805 4.25 ENST00000538488.2
proline rich protein BstNI subfamily 3
chr16_+_56682461 4.21 ENST00000562939.1
ENST00000394485.5
ENST00000567563.1
metallothionein 1X
novel transcript
chr17_-_41624541 4.17 ENST00000540235.5
ENST00000311208.13
keratin 17
chr7_+_155297776 4.17 ENST00000344756.8
ENST00000425172.1
ENST00000340368.9
ENST00000342407.5
insulin induced gene 1
chr11_-_102955705 4.16 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
matrix metallopeptidase 13
chr6_+_63572472 4.15 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chr11_-_5254741 4.13 ENST00000444587.1
ENST00000336906.6
ENST00000642908.1
ENST00000647543.1
hemoglobin subunit gamma 2
novel protein
chr2_-_85668172 4.12 ENST00000428225.5
ENST00000519937.7
surfactant protein B
chr16_+_57372481 3.98 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr3_-_24494791 3.98 ENST00000431815.5
ENST00000356447.9
ENST00000418247.1
ENST00000416420.5
ENST00000396671.7
thyroid hormone receptor beta
chr2_+_134838610 3.96 ENST00000356140.10
ENST00000392928.5
aminocarboxymuconate semialdehyde decarboxylase
chr12_-_14885845 3.93 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr17_-_41624803 3.89 ENST00000463128.5
keratin 17
chr11_-_5249836 3.86 ENST00000632727.1
ENST00000330597.5
hemoglobin subunit gamma 1
chr12_+_12891554 3.79 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr9_-_33447553 3.79 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr11_-_102843597 3.77 ENST00000299855.10
matrix metallopeptidase 3
chr16_+_57372465 3.76 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr17_-_41624382 3.69 ENST00000577817.3
keratin 17
chr15_-_40874216 3.69 ENST00000220507.5
ras homolog family member V
chr17_+_81035122 3.67 ENST00000321280.11
ENST00000575989.5
ENST00000428708.7
ENST00000575712.5
ENST00000575245.5
ENST00000435091.7
ENST00000321300.10
BAR/IMD domain containing adaptor protein 2
chr21_-_42366525 3.60 ENST00000291527.3
trefoil factor 1
chr12_+_12891853 3.60 ENST00000534831.1
G protein-coupled receptor class C group 5 member A
chr6_-_132714045 3.60 ENST00000367928.5
vanin 1
chr9_+_89605004 3.59 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr4_+_73836667 3.55 ENST00000226317.10
C-X-C motif chemokine ligand 6
chr1_-_40862354 3.50 ENST00000372638.4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr19_+_12938598 3.50 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr17_+_78187317 3.47 ENST00000409257.9
ENST00000591256.5
ENST00000589256.5
ENST00000588800.5
ENST00000591952.5
ENST00000327898.9
ENST00000586542.5
ENST00000586731.1
arylformamidase
chr8_-_23164020 3.47 ENST00000312584.4
TNF receptor superfamily member 10d
chr17_-_41505597 3.46 ENST00000336861.7
ENST00000246635.8
ENST00000587544.5
ENST00000587435.1
keratin 13
chrX_-_102516714 3.46 ENST00000289373.5
thymosin beta 15A
chr14_-_54902807 3.37 ENST00000543643.6
ENST00000536224.2
ENST00000395514.5
ENST00000491895.7
GTP cyclohydrolase 1
chr1_-_203186677 3.32 ENST00000255409.8
chitinase 3 like 1
chr16_+_2830368 3.27 ENST00000572863.1
zymogen granule protein 16B
chr2_-_217901986 3.25 ENST00000439083.5
tensin 1
chr7_+_116953306 3.22 ENST00000265437.9
ENST00000393451.7
suppression of tumorigenicity 7
chr1_-_149842736 3.17 ENST00000369159.2
H2A clustered histone 18
chr3_-_81761636 3.14 ENST00000429644.7
1,4-alpha-glucan branching enzyme 1
chr16_+_2830155 3.13 ENST00000382280.7
zymogen granule protein 16B
chr12_+_10929229 3.08 ENST00000381847.7
ENST00000396400.4
proline rich protein HaeIII subfamily 2
chr2_-_21043941 3.07 ENST00000399256.4
apolipoprotein B
chr4_-_109801978 3.06 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr19_+_840991 3.05 ENST00000234347.10
proteinase 3
chr1_-_59926724 3.04 ENST00000371204.4
cytochrome P450 family 2 subfamily J member 2
chr11_-_2929412 3.01 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr1_-_209652329 2.98 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chr4_+_20251896 2.98 ENST00000504154.6
slit guidance ligand 2
chr2_+_157257687 2.96 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr18_-_63644250 2.92 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr8_+_85438850 2.90 ENST00000285381.3
carbonic anhydrase 3
chr11_-_2161158 2.89 ENST00000421783.1
ENST00000397262.5
ENST00000381330.5
ENST00000250971.7
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr6_-_27146841 2.88 ENST00000356950.2
H2B clustered histone 12
chr14_-_24576240 2.87 ENST00000216336.3
cathepsin G
chr7_+_80638662 2.78 ENST00000394788.7
CD36 molecule
chr19_+_48965304 2.77 ENST00000331825.11
ferritin light chain
chr6_-_26123910 2.77 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr4_+_25655822 2.77 ENST00000504570.5
ENST00000382051.8
solute carrier family 34 member 2
chr16_+_57372525 2.74 ENST00000564948.1
C-X3-C motif chemokine ligand 1
chr16_+_78022538 2.73 ENST00000651443.1
ENST00000299642.10
C-type lectin domain family 3 member A
chr5_-_154478218 2.72 ENST00000231121.3
heart and neural crest derivatives expressed 1
chr22_+_39520553 2.69 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr10_+_94762673 2.67 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr8_-_27614681 2.66 ENST00000519472.5
ENST00000523589.5
ENST00000522413.5
ENST00000523396.1
ENST00000316403.15
clusterin
chr12_-_10884244 2.65 ENST00000543626.4
proline rich protein HaeIII subfamily 1
chr10_+_122560639 2.64 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr1_-_99766620 2.63 ENST00000646001.2
ferric chelate reductase 1
chr16_+_71358713 2.60 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr22_+_39520747 2.60 ENST00000676430.1
activating transcription factor 4
chr7_+_80638633 2.59 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr17_-_40885232 2.57 ENST00000167588.4
keratin 20
chr10_-_88952763 2.55 ENST00000224784.10
actin alpha 2, smooth muscle
chr3_+_109136707 2.52 ENST00000622536.6
chromosome 3 open reading frame 85
chr19_-_49640092 2.49 ENST00000246792.4
RAS related
chr12_+_54854505 2.47 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr19_+_10271093 2.46 ENST00000423829.2
ENST00000588645.1
ENST00000264832.8
intercellular adhesion molecule 1
chr7_+_116953482 2.42 ENST00000323984.8
ENST00000417919.5
suppression of tumorigenicity 7
chr15_+_74748838 2.40 ENST00000343932.5
cytochrome P450 family 1 subfamily A member 2
chr6_-_75493629 2.39 ENST00000393004.6
filamin A interacting protein 1
chr15_-_50265666 2.39 ENST00000543581.5
ENST00000267845.8
histidine decarboxylase
chr7_-_150302980 2.37 ENST00000252071.8
actin related protein 3C
chr19_+_859654 2.36 ENST00000592860.2
ENST00000327726.11
complement factor D
chr5_-_58460076 2.34 ENST00000274289.8
ENST00000617412.1
polo like kinase 2
chr11_+_68684534 2.33 ENST00000265643.4
galanin and GMAP prepropeptide
chr7_-_7535863 2.33 ENST00000399429.8
collagen type XXVIII alpha 1 chain
chr12_-_52493250 2.32 ENST00000330722.7
keratin 6A
chr7_+_116953379 2.30 ENST00000393449.5
suppression of tumorigenicity 7
chr4_+_73869385 2.30 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr10_+_122560751 2.29 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr1_+_149851053 2.26 ENST00000607355.2
H2A clustered histone 19
chr5_-_139198358 2.26 ENST00000394817.7
SIL1 nucleotide exchange factor
chr18_+_59220149 2.26 ENST00000256857.7
ENST00000529320.2
ENST00000420468.6
gastrin releasing peptide
chr3_-_170870033 2.24 ENST00000466674.5
ENST00000295830.13
ENST00000463836.1
ribosomal protein L22 like 1
chr17_+_58238426 2.23 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
lactoperoxidase
chr1_+_37474572 2.21 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr21_-_34526815 2.21 ENST00000492600.1
regulator of calcineurin 1
chr7_+_76302665 2.20 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
heat shock protein family B (small) member 1
chr6_-_25726553 2.19 ENST00000297012.5
H2A clustered histone 1
chr10_+_52314272 2.18 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr16_+_56651885 2.18 ENST00000334346.3
ENST00000562399.1
metallothionein 1B
chr6_+_25726767 2.17 ENST00000274764.5
H2B clustered histone 1
chr3_-_24494842 2.17 ENST00000646209.2
thyroid hormone receptor beta
chr7_-_41703062 2.15 ENST00000242208.5
inhibin subunit beta A
chr5_+_40909490 2.14 ENST00000313164.10
complement C7
chr21_-_34526850 2.10 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr6_-_49636832 2.09 ENST00000371175.10
ENST00000646272.1
ENST00000646939.1
ENST00000618248.3
ENST00000229810.9
ENST00000646963.1
Rh associated glycoprotein
chr1_+_161258738 2.07 ENST00000504449.2
Purkinje cell protein 4 like 1
chr3_-_100993507 2.06 ENST00000284322.10
ABI family member 3 binding protein
chr17_+_7281711 2.05 ENST00000317370.13
ENST00000571308.5
solute carrier family 2 member 4
chr9_+_133636355 2.01 ENST00000393056.8
dopamine beta-hydroxylase
chr1_+_152908538 1.99 ENST00000368764.4
involucrin
chr3_-_100993409 1.99 ENST00000471714.6
ABI family member 3 binding protein
chr20_+_45207025 1.98 ENST00000372781.4
semenogelin 1
chr19_-_8321354 1.98 ENST00000301457.3
NADH:ubiquinone oxidoreductase subunit A7
chr21_-_26845402 1.97 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_-_76036060 1.96 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr6_+_143126183 1.95 ENST00000458219.1
androgen induced 1
chr1_-_153565535 1.94 ENST00000368707.5
S100 calcium binding protein A2
chr19_+_2476118 1.94 ENST00000215631.9
ENST00000587345.1
growth arrest and DNA damage inducible beta
chr10_-_32935511 1.92 ENST00000423113.5
integrin subunit beta 1
chr10_-_112183698 1.91 ENST00000369425.5
ENST00000348367.9
glycerol-3-phosphate acyltransferase, mitochondrial

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 23.2 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
3.5 10.5 GO:0051041 positive regulation of calcium-independent cell-cell adhesion(GO:0051041)
3.5 17.3 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
3.3 9.9 GO:0014016 neuroblast differentiation(GO:0014016)
2.8 11.2 GO:0030185 nitric oxide transport(GO:0030185)
2.4 7.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
2.3 16.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
2.3 6.9 GO:1990641 response to iron ion starvation(GO:1990641)
2.2 17.9 GO:0034371 chylomicron remodeling(GO:0034371)
2.2 6.7 GO:0000103 sulfate assimilation(GO:0000103)
2.2 6.6 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of activation of membrane attack complex(GO:0001970) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
2.2 4.3 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
2.1 6.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
2.1 2.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
1.9 5.8 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
1.9 20.7 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
1.7 5.2 GO:0035425 autocrine signaling(GO:0035425)
1.6 7.9 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.5 4.5 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
1.4 4.3 GO:0002125 maternal aggressive behavior(GO:0002125)
1.4 7.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
1.4 4.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.3 5.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.3 4.0 GO:1902688 regulation of NAD metabolic process(GO:1902688)
1.3 6.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.2 4.6 GO:0044010 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.1 8.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.1 11.5 GO:0008050 female courtship behavior(GO:0008050)
1.1 4.5 GO:0044691 tooth eruption(GO:0044691)
1.1 3.4 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
1.1 3.3 GO:0006589 octopamine biosynthetic process(GO:0006589) homoiothermy(GO:0042309) octopamine metabolic process(GO:0046333)
1.1 22.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
1.0 3.0 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.0 3.0 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
1.0 2.9 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.9 3.8 GO:0070295 renal water absorption(GO:0070295)
0.9 4.6 GO:0035962 response to interleukin-13(GO:0035962)
0.9 2.7 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.9 4.4 GO:1902896 terminal web assembly(GO:1902896)
0.9 3.5 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.9 5.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.8 0.8 GO:2000405 negative regulation of T cell migration(GO:2000405)
0.8 26.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.8 69.6 GO:0006953 acute-phase response(GO:0006953)
0.8 4.8 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.7 2.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.7 2.2 GO:0100012 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.7 2.2 GO:0060279 negative regulation of B cell differentiation(GO:0045578) positive regulation of ovulation(GO:0060279)
0.7 6.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.6 1.9 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.6 5.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.6 0.6 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.6 8.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.6 1.8 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.6 1.8 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.6 17.1 GO:0015671 oxygen transport(GO:0015671)
0.6 2.3 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710) cytolysis in other organism involved in symbiotic interaction(GO:0051801)
0.6 6.9 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 1.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.6 0.6 GO:1904432 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.6 6.1 GO:0043589 skin morphogenesis(GO:0043589)
0.5 6.0 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.5 1.6 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.5 24.1 GO:0019731 antibacterial humoral response(GO:0019731)
0.5 1.6 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.5 5.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 2.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5 8.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.5 2.6 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.5 5.0 GO:1902527 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.5 2.0 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 2.5 GO:0022614 membrane to membrane docking(GO:0022614)
0.5 1.9 GO:0051795 positive regulation of catagen(GO:0051795)
0.5 13.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.5 3.8 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.5 11.8 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.5 7.0 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.4 1.7 GO:0018277 protein deamination(GO:0018277)
0.4 2.6 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4 1.2 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.4 6.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 2.4 GO:0001692 histamine metabolic process(GO:0001692)
0.4 1.1 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.4 2.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.4 7.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 1.0 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.7 GO:0035106 operant conditioning(GO:0035106)
0.3 2.7 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 4.9 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.3 5.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.3 2.7 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 1.2 GO:0046968 peptide antigen transport(GO:0046968)
0.3 1.2 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 1.7 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 3.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.3 1.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 0.5 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.3 3.7 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.3 8.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.3 3.6 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.3 1.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 3.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.3 0.8 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 10.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 1.7 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 4.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 12.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 0.7 GO:0048058 compound eye corneal lens development(GO:0048058)
0.2 2.3 GO:0036343 psychomotor behavior(GO:0036343)
0.2 4.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 5.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 2.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 5.2 GO:0002003 angiotensin maturation(GO:0002003)
0.2 1.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 3.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 3.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 0.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 1.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 1.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.2 4.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 12.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.2 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.2 3.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 5.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.8 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 1.4 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 3.9 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 8.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 1.0 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 1.3 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 3.6 GO:0030728 ovulation(GO:0030728)
0.1 0.9 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 9.6 GO:0042246 tissue regeneration(GO:0042246)
0.1 0.3 GO:0060032 notochord regression(GO:0060032)
0.1 4.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.5 GO:0010269 response to selenium ion(GO:0010269)
0.1 1.8 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 1.0 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.1 4.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 12.3 GO:0070268 cornification(GO:0070268)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 1.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 7.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 5.1 GO:0031424 keratinization(GO:0031424)
0.1 0.3 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 0.2 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.1 1.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.9 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.5 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 5.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.5 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.1 4.9 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831) proximal/distal axis specification(GO:0009946)
0.0 1.8 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102) response to isolation stress(GO:0035900)
0.0 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 4.1 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.5 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 3.6 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.6 GO:0030903 notochord development(GO:0030903)
0.0 2.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 1.3 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 3.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 1.3 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 5.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 3.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.7 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.7 GO:0009648 photoperiodism(GO:0009648)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 2.4 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.8 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.7 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 1.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 2.9 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.1 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.0 GO:1900158 negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 2.4 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 1.1 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
2.1 16.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.9 5.7 GO:0070195 growth hormone receptor complex(GO:0070195)
1.8 5.3 GO:1990617 CHOP-ATF4 complex(GO:1990617)
1.7 79.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
1.6 7.9 GO:1990742 microvesicle(GO:1990742)
1.5 4.5 GO:0005584 collagen type I trimer(GO:0005584)
1.2 17.1 GO:0005833 hemoglobin complex(GO:0005833)
0.8 4.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.7 4.4 GO:1990357 terminal web(GO:1990357)
0.7 2.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.7 2.7 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.5 9.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 1.9 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.5 4.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.4 3.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.4 8.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 2.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 6.9 GO:0045179 apical cortex(GO:0045179)
0.3 4.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 6.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 3.0 GO:0005610 laminin-5 complex(GO:0005610)
0.3 4.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.3 1.7 GO:0044753 amphisome(GO:0044753)
0.3 1.3 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.2 24.8 GO:0035580 specific granule lumen(GO:0035580)
0.2 2.1 GO:0005579 membrane attack complex(GO:0005579)
0.2 56.5 GO:0072562 blood microparticle(GO:0072562)
0.2 2.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 3.0 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 16.1 GO:0045095 keratin filament(GO:0045095)
0.2 2.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 5.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 6.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.4 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 4.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 8.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.2 GO:0070701 mucus layer(GO:0070701)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 5.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 4.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.7 GO:0070876 SOSS complex(GO:0070876)
0.1 2.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 13.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.1 0.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 152.6 GO:0005615 extracellular space(GO:0005615)
0.1 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.6 GO:0005921 gap junction(GO:0005921)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 3.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 2.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 11.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 3.9 GO:0005882 intermediate filament(GO:0005882)
0.0 4.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:1990745 EARP complex(GO:1990745)
0.0 1.7 GO:0001772 immunological synapse(GO:0001772)
0.0 1.8 GO:0031201 SNARE complex(GO:0031201)
0.0 1.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 3.3 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.0 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 13.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 20.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 8.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 20.0 GO:0033265 choline binding(GO:0033265)
4.7 23.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
3.6 18.0 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
3.5 10.5 GO:0031737 CX3C chemokine receptor binding(GO:0031737)
3.5 17.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
3.3 26.7 GO:0001849 complement component C1q binding(GO:0001849)
2.2 6.6 GO:0035375 zymogen binding(GO:0035375)
2.0 7.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.9 9.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.5 10.8 GO:0030492 hemoglobin binding(GO:0030492)
1.5 12.1 GO:0035473 lipase binding(GO:0035473)
1.3 11.8 GO:0042289 MHC class II protein binding(GO:0042289)
1.3 5.2 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.2 58.8 GO:0042056 chemoattractant activity(GO:0042056)
1.1 3.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.1 4.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.0 15.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.0 6.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.9 7.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.9 3.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.9 17.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.9 18.8 GO:0019841 retinol binding(GO:0019841)
0.8 4.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.7 2.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.7 1.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.6 1.8 GO:0097689 iron channel activity(GO:0097689)
0.6 6.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 10.8 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.6 2.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.5 1.6 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.5 11.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 3.8 GO:0015254 glycerol channel activity(GO:0015254)
0.5 1.6 GO:0016497 substance K receptor activity(GO:0016497)
0.5 6.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.5 7.1 GO:0033691 sialic acid binding(GO:0033691)
0.5 4.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 8.5 GO:0019864 IgG binding(GO:0019864)
0.4 2.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 1.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 7.2 GO:0008430 selenium binding(GO:0008430)
0.3 0.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.3 3.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.3 2.3 GO:0004966 galanin receptor activity(GO:0004966)
0.3 3.0 GO:0043237 laminin-1 binding(GO:0043237)
0.3 0.9 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 4.8 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 1.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 4.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 44.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 2.2 GO:0034711 inhibin binding(GO:0034711)
0.2 2.8 GO:0042301 phosphate ion binding(GO:0042301)
0.2 4.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 9.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 1.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.8 GO:0045569 TRAIL binding(GO:0045569)
0.2 4.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 6.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 7.0 GO:0070628 proteasome binding(GO:0070628)
0.2 3.3 GO:0004568 chitinase activity(GO:0004568)
0.2 7.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 0.8 GO:0051431 histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 1.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 2.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 1.8 GO:0070700 BMP receptor binding(GO:0070700)
0.2 1.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 6.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 3.3 GO:0008199 ferric iron binding(GO:0008199)
0.2 1.3 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 23.8 GO:0005518 collagen binding(GO:0005518)
0.1 2.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 1.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 1.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.7 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.1 0.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 3.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 3.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 2.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 1.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.2 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.1 0.3 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.8 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 2.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 22.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.0 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 5.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.2 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 1.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 4.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.4 GO:0017166 vinculin binding(GO:0017166)
0.0 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 4.5 GO:0051087 chaperone binding(GO:0051087)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 4.1 GO:0002020 protease binding(GO:0002020)
0.0 6.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688) 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 8.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 17.3 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.0 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 19.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 6.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 22.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 12.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 20.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 17.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2 10.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 5.5 ST ADRENERGIC Adrenergic Pathway
0.2 10.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 10.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 10.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 5.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 8.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 6.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 3.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 36.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 28.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 29.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 3.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 13.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 3.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 2.3 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 29.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.1 20.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.0 46.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.8 19.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 7.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.5 8.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 11.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 0.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.4 14.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 26.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 3.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 13.2 REACTOME DEFENSINS Genes involved in Defensins
0.3 6.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 6.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 4.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 5.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 2.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 2.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 4.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 4.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 4.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.8 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.1 9.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 14.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 11.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 17.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 5.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 7.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 4.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 4.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 3.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 4.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling