Project
Illumina Body Map 2 (GSE30611)
Navigation
Downloads
Results for TBX19
Z-value: 1.32
Motif logo
Transcription factors associated with TBX19
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBX19 | hg38_v1_chr1_+_168280872_168280882 | 0.53 | 2.0e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_55024250 Show fit | 12.45 |
ENST00000231009.3
|
granzyme K |
|
| chr14_-_106185387 Show fit | 9.29 |
ENST00000390605.2
|
immunoglobulin heavy variable 1-18 |
|
| chr1_+_116754422 Show fit | 6.39 |
ENST00000369478.4
ENST00000369477.1 |
CD2 molecule |
|
| chr14_-_106154113 Show fit | 6.00 |
ENST00000390603.2
|
immunoglobulin heavy variable 3-15 |
|
| chr5_+_35856883 Show fit | 5.84 |
ENST00000506850.5
ENST00000303115.8 ENST00000511982.1 |
interleukin 7 receptor |
|
| chr12_-_9607903 Show fit | 5.53 |
ENST00000229402.4
|
killer cell lectin like receptor B1 |
|
| chr1_+_207454230 Show fit | 5.40 |
ENST00000367058.7
ENST00000367059.3 ENST00000367057.8 |
complement C3d receptor 2 |
|
| chrX_+_12906639 Show fit | 5.25 |
ENST00000311912.5
|
toll like receptor 8 |
|
| chr14_+_20781139 Show fit | 5.11 |
ENST00000304677.3
|
ribonuclease A family member k6 |
|
| chr5_+_96876480 Show fit | 4.87 |
ENST00000437043.8
ENST00000379904.8 |
endoplasmic reticulum aminopeptidase 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TBX19
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 18.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 15.3 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 11.7 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 2.9 | 11.6 | GO:0035744 | T-helper 1 cell cytokine production(GO:0035744) |
| 1.3 | 9.2 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.0 | 9.1 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.6 | 8.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.1 | 8.3 | GO:0031295 | T cell costimulation(GO:0031295) |
| 0.4 | 7.0 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.4 | 6.5 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 26.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.3 | 18.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 11.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 6.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 5.2 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.1 | 5.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 4.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 4.6 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 3.9 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.2 | 3.5 | GO:0033093 | Weibel-Palade body(GO:0033093) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 39.0 | GO:0003823 | antigen binding(GO:0003823) |
| 0.3 | 18.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 13.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 11.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.9 | 9.2 | GO:0019863 | IgE binding(GO:0019863) |
| 0.0 | 9.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.3 | 8.9 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.4 | 6.5 | GO:0004875 | complement receptor activity(GO:0004875) |
| 1.9 | 5.8 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 0.0 | 5.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 6.0 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 5.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 5.4 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.1 | 3.7 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 3.5 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 3.4 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 2.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 2.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 2.1 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 13.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 5.8 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.4 | 5.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 5.2 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.1 | 5.1 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 5.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 3.7 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 3.5 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 3.5 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 2.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |