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Illumina Body Map 2 (GSE30611)

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Results for TBX19

Z-value: 1.32

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Transcription factors associated with TBX19

Gene Symbol Gene ID Gene Info
TBX19
ENSG00000143178.13 T-box transcription factor 19

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX19hg38_v1_chr1_+_168280872_1682808820.532.0e-03Click!

Activity profile of TBX19 motif

Sorted Z-values of TBX19 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_55024250 12.45 ENST00000231009.3
GZMK
granzyme K
chr14_-_106185387 9.29 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr1_+_116754422 6.39 ENST00000369478.4
ENST00000369477.1
CD2
CD2 molecule
chr14_-_106154113 6.00 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chr5_+_35856883 5.84 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr12_-_9607903 5.53 ENST00000229402.4
KLRB1
killer cell lectin like receptor B1
chr1_+_207454230 5.40 ENST00000367058.7
ENST00000367059.3
ENST00000367057.8
CR2
complement C3d receptor 2
chrX_+_12906639 5.25 ENST00000311912.5
TLR8
toll like receptor 8
chr14_+_20781139 5.11 ENST00000304677.3
RNASE6
ribonuclease A family member k6
chr5_+_96876480 4.87 ENST00000437043.8
ENST00000379904.8
ERAP2
endoplasmic reticulum aminopeptidase 2
chr2_-_89027700 4.85 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr7_+_142560423 4.85 ENST00000620569.1
TRBV12-3
T cell receptor beta variable 12-3
chr2_+_90114838 4.77 ENST00000417279.3
IGKV3D-15
immunoglobulin kappa variable 3D-15
chr1_-_160647037 4.67 ENST00000302035.11
SLAMF1
signaling lymphocytic activation molecule family member 1
chr14_-_106360320 4.66 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr1_+_160796157 4.63 ENST00000263285.11
ENST00000368039.2
LY9
lymphocyte antigen 9
chr19_-_7702124 4.63 ENST00000597921.6
FCER2
Fc fragment of IgE receptor II
chr19_-_7702139 4.60 ENST00000346664.9
FCER2
Fc fragment of IgE receptor II
chr7_+_142345412 4.37 ENST00000390392.3
TRBV4-2
T cell receptor beta variable 4-2
chr7_+_142492121 4.36 ENST00000390374.3
TRBV7-6
T cell receptor beta variable 7-6
chr21_+_38256698 4.13 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr5_+_96875978 4.05 ENST00000510373.5
ERAP2
endoplasmic reticulum aminopeptidase 2
chr1_-_161069666 3.89 ENST00000368016.7
ARHGAP30
Rho GTPase activating protein 30
chr1_-_160646958 3.80 ENST00000538290.2
SLAMF1
signaling lymphocytic activation molecule family member 1
chr6_-_36547400 3.77 ENST00000229812.8
STK38
serine/threonine kinase 38
chr12_+_8123609 3.69 ENST00000229332.12
CLEC4A
C-type lectin domain family 4 member A
chr14_-_106511856 3.69 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr2_-_112836702 3.67 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
IL1B
interleukin 1 beta
chr1_-_161069962 3.50 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr15_-_55289756 3.50 ENST00000336787.6
RAB27A
RAB27A, member RAS oncogene family
chr22_+_39926591 3.49 ENST00000420971.5
GRAP2
GRB2 related adaptor protein 2
chr9_-_114388020 3.49 ENST00000312033.3
AKNA
AT-hook transcription factor
chr1_+_153990749 3.39 ENST00000651669.1
RPS27
ribosomal protein S27
chr2_-_88861563 3.28 ENST00000624935.3
ENST00000390241.3
ENSG00000240040.6
IGKJ2
novel transcript
immunoglobulin kappa joining 2
chr10_-_119536533 3.20 ENST00000392865.5
RGS10
regulator of G protein signaling 10
chr1_-_160647287 3.11 ENST00000235739.6
SLAMF1
signaling lymphocytic activation molecule family member 1
chr7_+_142450941 3.06 ENST00000390368.2
TRBV6-5
T cell receptor beta variable 6-5
chr19_-_54313074 3.02 ENST00000486742.2
ENST00000432233.8
LILRA5
leukocyte immunoglobulin like receptor A5
chr1_-_161069857 2.98 ENST00000368013.8
ARHGAP30
Rho GTPase activating protein 30
chr5_-_100903252 2.81 ENST00000231461.10
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr2_+_143129379 2.79 ENST00000295095.11
ARHGAP15
Rho GTPase activating protein 15
chr4_+_15703057 2.56 ENST00000265016.9
ENST00000382346.7
BST1
bone marrow stromal cell antigen 1
chr2_+_90234809 2.51 ENST00000443397.5
IGKV3D-7
immunoglobulin kappa variable 3D-7
chrX_+_108045050 2.44 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr7_-_38354517 2.43 ENST00000390345.2
TRGV4
T cell receptor gamma variable 4
chr12_+_8123837 2.37 ENST00000345999.9
ENST00000352620.9
ENST00000360500.5
CLEC4A
C-type lectin domain family 4 member A
chr12_-_110689751 2.34 ENST00000439744.6
ENST00000549442.5
HVCN1
hydrogen voltage gated channel 1
chr1_+_168280872 2.30 ENST00000367821.8
TBX19
T-box transcription factor 19
chr12_-_48925483 2.29 ENST00000550765.6
ENST00000552878.5
ENST00000453172.2
FKBP11
FKBP prolyl isomerase 11
chr1_+_100345018 2.27 ENST00000635056.2
ENST00000647005.1
CDC14A
cell division cycle 14A
chr19_+_49487510 2.21 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr1_-_120051714 2.18 ENST00000579475.7
NOTCH2
notch receptor 2
chr2_-_88861920 2.16 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr5_-_100903214 2.09 ENST00000451528.2
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr2_+_89851723 2.09 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr6_-_46735693 2.08 ENST00000537365.1
PLA2G7
phospholipase A2 group VII
chr2_-_85409805 2.06 ENST00000449030.5
CAPG
capping actin protein, gelsolin like
chr10_-_93482194 2.05 ENST00000358334.9
ENST00000371488.3
MYOF
myoferlin
chr10_-_93482326 2.03 ENST00000359263.9
MYOF
myoferlin
chr6_-_2841853 1.91 ENST00000380739.6
SERPINB1
serpin family B member 1
chr10_-_93482287 1.88 ENST00000371489.5
MYOF
myoferlin
chr8_+_109362453 1.86 ENST00000378402.10
PKHD1L1
PKHD1 like 1
chr22_+_44677044 1.85 ENST00000006251.11
PRR5
proline rich 5
chr2_-_88979016 1.84 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr1_+_158930778 1.76 ENST00000458222.5
PYHIN1
pyrin and HIN domain family member 1
chr18_+_63887698 1.76 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
SERPINB2
serpin family B member 2
chr5_-_78985288 1.74 ENST00000264914.10
ARSB
arylsulfatase B
chr2_-_213151590 1.69 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKZF2
IKAROS family zinc finger 2
chr5_-_131532993 1.68 ENST00000504575.5
ENST00000513227.5
RAPGEF6
Rap guanine nucleotide exchange factor 6
chr19_-_2292024 1.63 ENST00000585527.1
LINGO3
leucine rich repeat and Ig domain containing 3
chr6_-_42746054 1.63 ENST00000372876.2
TBCC
tubulin folding cofactor C
chr22_+_44677077 1.59 ENST00000403581.5
PRR5
proline rich 5
chr17_-_39926839 1.56 ENST00000394169.5
ORMDL3
ORMDL sphingolipid biosynthesis regulator 3
chr18_-_2982873 1.51 ENST00000584915.1
LPIN2
lipin 2
chr1_+_32292067 1.48 ENST00000373548.8
ENST00000428704.1
HDAC1
histone deacetylase 1
chr12_-_57006476 1.48 ENST00000300101.3
ZBTB39
zinc finger and BTB domain containing 39
chr5_-_178232759 1.47 ENST00000308158.10
PHYKPL
5-phosphohydroxy-L-lysine phospho-lyase
chr16_-_74700845 1.47 ENST00000308807.12
ENST00000573267.1
MLKL
mixed lineage kinase domain like pseudokinase
chr11_-_22625804 1.43 ENST00000327470.6
FANCF
FA complementation group F
chr9_+_75890664 1.41 ENST00000376767.7
ENST00000674117.1
ENST00000376752.8
PCSK5
proprotein convertase subtilisin/kexin type 5
chr10_-_12195837 1.41 ENST00000444732.1
ENST00000378940.7
ENST00000491614.6
NUDT5
nudix hydrolase 5
chrX_+_108044967 1.36 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr1_-_176207220 1.35 ENST00000367669.8
COP1
COP1 E3 ubiquitin ligase
chr16_-_11598464 1.35 ENST00000571627.5
LITAF
lipopolysaccharide induced TNF factor
chr10_-_12195821 1.33 ENST00000378937.7
ENST00000378927.7
NUDT5
nudix hydrolase 5
chr20_+_45207025 1.33 ENST00000372781.4
SEMG1
semenogelin 1
chr16_+_33827140 1.32 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr3_+_31981740 1.31 ENST00000360311.5
ZNF860
zinc finger protein 860
chr12_-_10453330 1.31 ENST00000347831.9
ENST00000359151.8
KLRC1
killer cell lectin like receptor C1
chr2_+_171453122 1.29 ENST00000611110.4
ENST00000339506.7
DCAF17
DDB1 and CUL4 associated factor 17
chr1_+_78620432 1.25 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
IFI44L
interferon induced protein 44 like
chr4_-_15681454 1.20 ENST00000507899.1
ENST00000510802.5
FBXL5
F-box and leucine rich repeat protein 5
chr5_-_178232537 1.16 ENST00000476170.2
ENST00000323594.8
PHYKPL
5-phosphohydroxy-L-lysine phospho-lyase
chr12_-_8066331 1.15 ENST00000546241.1
ENST00000307637.5
C3AR1
complement C3a receptor 1
chr12_+_112906777 1.12 ENST00000452357.7
ENST00000445409.7
OAS1
2'-5'-oligoadenylate synthetase 1
chr11_+_72227881 1.10 ENST00000538751.5
ENST00000541756.5
INPPL1
inositol polyphosphate phosphatase like 1
chr10_-_5185104 1.10 ENST00000648824.1
ENST00000650030.1
AKR1C8P
aldo-keto reductase family 1 member C8, pseudogene
chr5_-_176034680 1.03 ENST00000514861.5
THOC3
THO complex 3
chr15_-_68229658 1.03 ENST00000565471.6
ENST00000637494.1
ENST00000636314.1
ENST00000637667.1
ENST00000564752.1
ENST00000566347.5
ENST00000249806.11
ENST00000562767.2
CLN6
ENSG00000260007.3
CLN6 transmembrane ER protein
novel protein
chr15_+_67125707 1.02 ENST00000540846.6
SMAD3
SMAD family member 3
chr6_-_26216673 1.00 ENST00000541790.3
H2BC8
H2B clustered histone 8
chrX_+_120604084 0.99 ENST00000371317.10
MCTS1
MCTS1 re-initiation and release factor
chr2_+_71453538 0.99 ENST00000258104.8
DYSF
dysferlin
chr2_+_3575250 0.99 ENST00000645674.2
RPS7
ribosomal protein S7
chr20_-_46363174 0.98 ENST00000372227.5
SLC35C2
solute carrier family 35 member C2
chr7_+_149147422 0.97 ENST00000475153.6
ZNF398
zinc finger protein 398
chr7_-_47539240 0.97 ENST00000450444.5
TNS3
tensin 3
chr21_+_29300111 0.96 ENST00000451655.5
BACH1
BTB domain and CNC homolog 1
chr7_+_93906557 0.95 ENST00000248572.10
ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1
G protein subunit gamma transducin 1
chr1_+_150926336 0.95 ENST00000271640.9
ENST00000448029.5
ENST00000368962.6
ENST00000534805.5
ENST00000368969.8
ENST00000368963.5
ENST00000498193.5
SETDB1
SET domain bifurcated histone lysine methyltransferase 1
chr5_-_95081482 0.95 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr9_-_97922487 0.94 ENST00000455506.1
ENST00000375117.8
ENST00000375119.8
ENST00000611338.4
TRMO
tRNA methyltransferase O
chr5_-_78985249 0.94 ENST00000565165.2
ARSB
arylsulfatase B
chr1_+_78620722 0.91 ENST00000679848.1
IFI44L
interferon induced protein 44 like
chr19_-_46023046 0.91 ENST00000008938.5
PGLYRP1
peptidoglycan recognition protein 1
chr17_-_41140487 0.87 ENST00000345847.4
KRTAP4-6
keratin associated protein 4-6
chr14_-_106875069 0.87 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr19_-_44304968 0.87 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
ZNF235
zinc finger protein 235
chr1_+_212285383 0.85 ENST00000261461.7
PPP2R5A
protein phosphatase 2 regulatory subunit B'alpha
chr6_-_31684040 0.85 ENST00000375863.7
LY6G5C
lymphocyte antigen 6 family member G5C
chr17_+_38717424 0.84 ENST00000615858.1
MLLT6
MLLT6, PHD finger containing
chr1_+_25616780 0.84 ENST00000374332.9
MAN1C1
mannosidase alpha class 1C member 1
chr18_-_21600645 0.84 ENST00000269214.10
ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1
chr21_+_29300770 0.83 ENST00000447177.5
BACH1
BTB domain and CNC homolog 1
chr14_-_106507476 0.82 ENST00000390621.3
IGHV1-45
immunoglobulin heavy variable 1-45
chr1_+_171512032 0.82 ENST00000426496.6
PRRC2C
proline rich coiled-coil 2C
chr1_-_150697128 0.82 ENST00000427665.1
ENST00000271732.8
GOLPH3L
golgi phosphoprotein 3 like
chr13_+_50909745 0.80 ENST00000422660.6
ENST00000645188.1
ENST00000646731.1
ENST00000643774.1
ENST00000646960.1
ENST00000637648.2
ENST00000336617.8
RNASEH2B
ribonuclease H2 subunit B
chr1_+_206083540 0.79 ENST00000603378.5
ENST00000603488.5
RHEX
regulator of hemoglobinization and erythroid cell expansion
chr19_-_344786 0.77 ENST00000264819.7
MIER2
MIER family member 2
chr8_+_32548210 0.77 ENST00000523079.5
ENST00000650919.1
NRG1
neuregulin 1
chr3_+_46163465 0.75 ENST00000357422.2
CCR3
C-C motif chemokine receptor 3
chr6_+_85449584 0.75 ENST00000369651.7
NT5E
5'-nucleotidase ecto
chr11_-_59668981 0.75 ENST00000300146.10
PATL1
PAT1 homolog 1, processing body mRNA decay factor
chr2_-_200888993 0.75 ENST00000409264.6
ENST00000392283.9
PPIL3
peptidylprolyl isomerase like 3
chr1_-_150974867 0.74 ENST00000271688.10
CERS2
ceramide synthase 2
chr11_-_65121780 0.74 ENST00000525297.5
ENST00000529259.1
FAU
FAU ubiquitin like and ribosomal protein S30 fusion
chr9_+_75890639 0.74 ENST00000545128.5
PCSK5
proprotein convertase subtilisin/kexin type 5
chr18_+_62539511 0.72 ENST00000586834.1
ZCCHC2
zinc finger CCHC-type containing 2
chr8_-_19682576 0.72 ENST00000332246.10
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_+_57657736 0.71 ENST00000529773.2
ENST00000533905.1
ENST00000525602.1
ENST00000533682.2
ENST00000302731.4
CLP1
cleavage factor polyribonucleotide kinase subunit 1
chr3_-_71493500 0.71 ENST00000648380.1
ENST00000650295.1
FOXP1
forkhead box P1
chr20_+_3209469 0.68 ENST00000380113.8
ENST00000455664.6
ENST00000399838.3
ITPA
inosine triphosphatase
chr19_-_38847423 0.67 ENST00000647557.1
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr1_-_100132892 0.67 ENST00000287482.6
SASS6
SAS-6 centriolar assembly protein
chr16_+_20674493 0.64 ENST00000561584.5
ACSM3
acyl-CoA synthetase medium chain family member 3
chr19_-_40090860 0.63 ENST00000599972.1
ENST00000450241.6
ENST00000595687.6
ENST00000340963.9
ZNF780A
zinc finger protein 780A
chr19_+_4247074 0.62 ENST00000262962.12
YJU2
YJU2 splicing factor homolog
chr6_-_26285526 0.61 ENST00000377727.2
H4C8
H4 clustered histone 8
chr4_+_26319636 0.61 ENST00000342295.6
ENST00000506956.5
ENST00000512671.6
ENST00000345843.8
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_+_100133135 0.61 ENST00000370143.5
ENST00000370141.7
TRMT13
tRNA methyltransferase 13 homolog
chr9_-_113410666 0.59 ENST00000374171.5
POLE3
DNA polymerase epsilon 3, accessory subunit
chr6_-_38639898 0.59 ENST00000481247.6
BTBD9
BTB domain containing 9
chr7_-_47539591 0.59 ENST00000442536.6
ENST00000458317.6
TNS3
tensin 3
chr7_-_148883474 0.57 ENST00000476773.5
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr14_+_58427686 0.54 ENST00000650904.1
ENST00000652326.2
ENST00000554463.5
ENST00000555833.5
KIAA0586
KIAA0586
chr6_+_26216928 0.54 ENST00000303910.4
H2AC8
H2A clustered histone 8
chr17_+_46511511 0.52 ENST00000576629.5
LRRC37A2
leucine rich repeat containing 37 member A2
chr1_-_167553745 0.51 ENST00000370509.5
CREG1
cellular repressor of E1A stimulated genes 1
chr10_-_11532275 0.50 ENST00000277575.5
USP6NL
USP6 N-terminal like
chr16_+_84768246 0.50 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr2_-_200889266 0.50 ENST00000443398.5
ENST00000286175.12
ENST00000409449.5
PPIL3
peptidylprolyl isomerase like 3
chr6_+_42879610 0.47 ENST00000493763.7
ENST00000304734.9
RPL7L1
ribosomal protein L7 like 1
chr20_-_5113032 0.47 ENST00000379299.6
ENST00000379286.6
ENST00000379279.6
ENST00000379283.6
TMEM230
transmembrane protein 230
chr1_-_63523175 0.47 ENST00000371092.7
ENST00000271002.15
ITGB3BP
integrin subunit beta 3 binding protein
chr3_-_101320558 0.47 ENST00000193391.8
IMPG2
interphotoreceptor matrix proteoglycan 2
chr12_+_104287015 0.45 ENST00000529546.5
ENST00000529751.1
ENST00000528079.6
ENST00000526580.5
TXNRD1
thioredoxin reductase 1
chr19_-_40090921 0.45 ENST00000595508.1
ENST00000414720.6
ENST00000455521.5
ENST00000595773.5
ENST00000683561.1
ENSG00000269749.1
ZNF780A
novel transcript
zinc finger protein 780A
chr20_-_5113067 0.44 ENST00000342308.10
ENST00000612323.4
ENST00000202834.11
TMEM230
transmembrane protein 230
chr16_-_86555021 0.44 ENST00000565482.1
ENST00000564364.5
ENST00000561989.5
ENST00000568037.5
ENST00000634347.1
ENST00000543303.6
ENST00000381214.9
ENST00000360900.11
ENST00000546093.5
ENST00000569000.5
ENST00000562994.5
ENST00000561522.1
MTHFSD
methenyltetrahydrofolate synthetase domain containing
chr17_-_41047267 0.43 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chrX_+_130401962 0.43 ENST00000305536.11
ENST00000370947.1
RBMX2
RNA binding motif protein X-linked 2
chr17_-_64505357 0.39 ENST00000583212.2
ENST00000578190.5
ENST00000579091.5
ENST00000583239.6
DDX5
DEAD-box helicase 5
chr4_+_25648011 0.38 ENST00000645788.1
SLC34A2
solute carrier family 34 member 2
chr1_+_40691689 0.38 ENST00000427410.6
ENST00000447388.7
ENST00000425457.6
ENST00000453631.5
ENST00000456393.6
NFYC
nuclear transcription factor Y subunit gamma
chr8_+_132962986 0.38 ENST00000518058.1
TG
thyroglobulin
chr20_-_462485 0.37 ENST00000681414.1
ENST00000680050.1
ENST00000681129.1
ENST00000354200.5
ENST00000679895.1
ENST00000681551.1
ENST00000681539.1
TBC1D20
TBC1 domain family member 20
chr2_-_200889136 0.37 ENST00000409361.5
PPIL3
peptidylprolyl isomerase like 3
chr11_+_119121559 0.37 ENST00000350777.7
ENST00000529988.5
ENST00000527410.3
HINFP
histone H4 transcription factor
chr1_+_113929600 0.36 ENST00000369558.5
ENST00000369561.8
HIPK1
homeodomain interacting protein kinase 1
chr13_+_50909905 0.34 ENST00000644034.1
ENST00000645955.1
RNASEH2B
ribonuclease H2 subunit B
chr3_-_98035295 0.33 ENST00000621172.4
GABRR3
gamma-aminobutyric acid type A receptor subunit rho3
chr6_-_116829037 0.32 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
GPRC6A
G protein-coupled receptor class C group 6 member A
chr5_-_115626161 0.32 ENST00000282382.8
TMED7-TICAM2
TMED7-TICAM2 readthrough
chrX_-_139832235 0.30 ENST00000327569.7
ENST00000361648.6
ATP11C
ATPase phospholipid transporting 11C
chr16_-_66550005 0.30 ENST00000527284.6
TK2
thymidine kinase 2
chr19_+_37371152 0.28 ENST00000483919.5
ENST00000588911.5
ENST00000587349.1
ZNF527
zinc finger protein 527
chr7_+_77122609 0.28 ENST00000285871.5
CCDC146
coiled-coil domain containing 146
chr17_+_6756035 0.27 ENST00000361842.8
ENST00000574907.5
XAF1
XIAP associated factor 1
chr15_-_60479080 0.27 ENST00000560072.5
ENST00000560406.5
ENST00000560520.1
ENST00000261520.9
ICE2
interactor of little elongation complex ELL subunit 2
chrX_-_19970298 0.26 ENST00000379687.7
ENST00000379682.8
BCLAF3
BCLAF1 and THRAP3 family member 3
chr6_-_15586006 0.26 ENST00000462989.6
DTNBP1
dystrobrevin binding protein 1
chr12_+_52069967 0.25 ENST00000336854.9
ENST00000550604.1
ENST00000553049.5
ENST00000548915.1
ATG101
autophagy related 101
chr2_+_200889411 0.25 ENST00000409357.5
ENST00000409129.2
NIF3L1
NGG1 interacting factor 3 like 1
chr11_-_56614874 0.24 ENST00000641076.1
OR5M1
olfactory receptor family 5 subfamily M member 1
chr7_-_76626127 0.24 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr15_+_30625966 0.24 ENST00000428041.4
ARHGAP11B
Rho GTPase activating protein 11B
chr3_-_47513677 0.24 ENST00000296149.9
ELP6
elongator acetyltransferase complex subunit 6
chr16_-_66549839 0.24 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
TK2
thymidine kinase 2
chr7_-_151440008 0.23 ENST00000491928.1
ENST00000644350.1
ENST00000337323.3
CRYGN
crystallin gamma N

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX19

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.6 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
1.3 9.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
1.2 3.7 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.0 5.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.9 2.7 GO:0019303 D-ribose catabolic process(GO:0019303)
0.7 1.3 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.6 6.4 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.6 8.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.5 3.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 5.8 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.4 1.8 GO:0061580 colon epithelial cell migration(GO:0061580)
0.4 6.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.4 7.0 GO:0001778 plasma membrane repair(GO:0001778)
0.3 2.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.3 1.6 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.3 0.9 GO:0051714 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.3 1.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 4.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.2 GO:0032455 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) nerve growth factor processing(GO:0032455)
0.2 3.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 0.7 GO:0046041 ITP metabolic process(GO:0046041)
0.2 4.6 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.2 18.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 0.6 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 0.7 GO:1900148 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.2 3.4 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.5 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 1.5 GO:0061198 fungiform papilla formation(GO:0061198)
0.2 3.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 15.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 3.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 2.6 GO:0006554 lysine catabolic process(GO:0006554)
0.1 0.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 2.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.8 GO:0046086 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.1 3.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.9 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 2.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.7 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 1.0 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 4.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.7 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 2.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.0 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 2.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 2.6 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 0.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.6 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.1 1.0 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 8.3 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.6 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 4.1 GO:0010107 potassium ion import(GO:0010107)
0.1 3.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 1.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 9.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 1.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.7 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 2.3 GO:0021983 pituitary gland development(GO:0021983)
0.0 1.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0015705 iodide transport(GO:0015705)
0.0 5.8 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 3.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0070376 regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 1.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 1.5 GO:0070266 necroptotic process(GO:0070266)
0.0 1.6 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 1.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 11.7 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.1 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.7 GO:0007099 centriole replication(GO:0007099)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0035456 response to interferon-beta(GO:0035456)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 18.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 1.6 GO:0035339 SPOTS complex(GO:0035339)
0.2 2.2 GO:0097452 GAIT complex(GO:0097452)
0.2 3.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 5.2 GO:0036020 endolysosome membrane(GO:0036020)
0.2 1.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 2.3 GO:0060091 kinocilium(GO:0060091)
0.2 0.9 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 2.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 3.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 6.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 1.0 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 2.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 26.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 5.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.3 GO:0035363 histone locus body(GO:0035363)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 4.6 GO:0005901 caveola(GO:0005901)
0.0 1.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 4.9 GO:0072562 blood microparticle(GO:0072562)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 11.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 3.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 2.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 2.5 GO:0043679 axon terminus(GO:0043679)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.9 9.2 GO:0019863 IgE binding(GO:0019863)
0.9 2.7 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.6 2.6 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.5 4.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 2.6 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.4 6.5 GO:0004875 complement receptor activity(GO:0004875)
0.4 1.8 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3 2.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 8.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 1.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 18.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 2.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2 0.9 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2 3.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 39.0 GO:0003823 antigen binding(GO:0003823)
0.2 2.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 4.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.9 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 0.7 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.7 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 3.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.5 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 3.5 GO:0031489 myosin V binding(GO:0031489)
0.1 1.0 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 3.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.7 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 1.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 2.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 1.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.2 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.0 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 11.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 5.1 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 2.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 2.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 13.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 9.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.6 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.4 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 4.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 9.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 5.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 6.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 3.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 5.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 5.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 3.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 5.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 3.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 5.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 13.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 5.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates