ISMARA results: TBX3

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Illumina Body Map 2 (GSE30611)

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Results for TBX3

Z-value: 0.98

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Transcription factors associated with TBX3

Gene Symbol	Gene ID	Gene Info
TBX3 Ensembl NCBI GeneCards UniProt	ENSG00000135111.16	T-box transcription factor 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TBX3	hg38_v1_chr12_-_114684151_114684221	-0.18	3.3e-01	Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_+_72054477 Show fit	4.52	ENST00000355906.10 ENST00000570083.5 ENST00000228226.12 ENST00000398131.6 ENST00000569639.5 ENST00000564499.5 ENST00000357763.8 ENST00000613898.1 ENST00000562526.5 ENST00000565574.5 ENST00000568417.6	HP Ensembl NCBI GeneCards UniProt Show fit	haptoglobin
chr16_+_72063226 Show fit	3.92	ENST00000540303.7 ENST00000356967.6 ENST00000561690.1	HPR Ensembl NCBI GeneCards UniProt Show fit	haptoglobin-related protein
chr3_+_149474688 Show fit	3.41	ENST00000305354.5 ENST00000465758.1	TM4SF4 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 4
chr13_-_46105009 Show fit	2.95	ENST00000439329.5 ENST00000674625.1 ENST00000181383.10	CPB2 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B2
chr4_-_83109843 Show fit	2.80	ENST00000411416.6	PLAC8 Ensembl NCBI GeneCards UniProt Show fit	placenta associated 8
chr5_+_55024250 Show fit	2.50	ENST00000231009.3	GZMK Ensembl NCBI GeneCards UniProt Show fit	granzyme K
chr2_+_113117889 Show fit	2.42	ENST00000361779.7 ENST00000259206.9 ENST00000354115.6	IL1RN Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor antagonist
chr2_-_88857582 Show fit	2.31	ENST00000390237.2	IGKC Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa constant
chr22_+_22895368 Show fit	2.09	ENST00000390321.2	IGLC1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda constant 1
chr17_-_7114240 Show fit	1.97	ENST00000446679.6	ASGR2 Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 2
chr14_-_106360320 Show fit	1.73	ENST00000390615.2	IGHV3-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-33
chr2_-_208254232 Show fit	1.70	ENST00000415913.5 ENST00000415282.5 ENST00000446179.5	IDH1 Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NADP(+)) 1
chrX_-_132489015 Show fit	1.70	ENST00000421707.1 ENST00000370853.8	MBNL3 Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 3
chr14_-_106005574 Show fit	1.66	ENST00000390595.3	IGHV1-3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-3
chr22_+_22720615 Show fit	1.64	ENST00000390309.2	IGLV3-19 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-19
chr14_-_94452766 Show fit	1.64	ENST00000334708.4	SERPINA11 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 11
chr20_+_58150896 Show fit	1.63	ENST00000371168.4	C20orf85 Ensembl NCBI GeneCards UniProt Show fit	chromosome 20 open reading frame 85
chr17_+_47209035 Show fit	1.62	ENST00000572316.5 ENST00000354968.5 ENST00000576874.5 ENST00000536623.6	MYL4 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 4
chr7_+_142345412 Show fit	1.61	ENST00000390392.3	TRBV4-2 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 4-2
chr4_+_154563003 Show fit	1.59	ENST00000302068.9 ENST00000509493.1	FGB Ensembl NCBI GeneCards UniProt Show fit	fibrinogen beta chain
chr11_-_10568571 Show fit	1.51	ENST00000529598.1	LYVE1 Ensembl NCBI GeneCards UniProt Show fit	lymphatic vessel endothelial hyaluronan receptor 1
chr7_+_142740206 Show fit	1.46	ENST00000422143.2	TRBV29-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 29-1
chr19_+_36100593 Show fit	1.43	ENST00000680211.1	WDR62 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 62
chr11_-_10568650 Show fit	1.42	ENST00000256178.8	LYVE1 Ensembl NCBI GeneCards UniProt Show fit	lymphatic vessel endothelial hyaluronan receptor 1
chr14_+_22007503 Show fit	1.27	ENST00000390447.3	TRAV19 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 19
chr4_+_40193642 Show fit	1.25	ENST00000617441.4 ENST00000503941.5	RHOH Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member H
chr22_+_22811737 Show fit	1.22	ENST00000390315.3	IGLV3-10 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-10
chr9_-_34729482 Show fit	1.18	ENST00000378788.4	FAM205A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 205 member A
chr7_+_22727147 Show fit	1.17	ENST00000426291.5 ENST00000401651.5 ENST00000258743.10 ENST00000407492.5 ENST00000401630.7 ENST00000406575.1	IL6 Ensembl NCBI GeneCards UniProt Show fit	interleukin 6
chr19_+_1077394 Show fit	1.16	ENST00000590577.2	ARHGAP45 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 45
chr1_+_212035717 Show fit	1.16	ENST00000366991.5	DTL Ensembl NCBI GeneCards UniProt Show fit	denticleless E3 ubiquitin protein ligase homolog
chr2_-_89010515 Show fit	1.14	ENST00000493819.1	IGKV1-9 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-9
chr3_+_108822778 Show fit	1.13	ENST00000295756.11	TRAT1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor associated transmembrane adaptor 1
chr6_-_32853813 Show fit	1.13	ENST00000643049.2	TAP1 Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr19_-_7702139 Show fit	1.13	ENST00000346664.9	FCER2 Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgE receptor II
chr3_+_52420955 Show fit	1.11	ENST00000465863.1	PHF7 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 7
chr11_+_78063851 Show fit	1.10	ENST00000281030.2	THRSP Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone responsive
chr2_+_90220727 Show fit	1.09	ENST00000471857.2	IGKV1D-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-8
chr17_+_55751378 Show fit	1.08	ENST00000325214.10	PCTP Ensembl NCBI GeneCards UniProt Show fit	phosphatidylcholine transfer protein
chr19_-_7702124 Show fit	1.08	ENST00000597921.6	FCER2 Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgE receptor II
chr21_-_14546297 Show fit	1.05	ENST00000400566.6 ENST00000400564.5	SAMSN1 Ensembl NCBI GeneCards UniProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr12_+_7062583 Show fit	1.05	ENST00000542978.1	C1S Ensembl NCBI GeneCards UniProt Show fit	complement C1s
chr12_+_57455266 Show fit	1.05	ENST00000266646.3	INHBE Ensembl NCBI GeneCards UniProt Show fit	inhibin subunit beta E
chr9_-_110337808 Show fit	1.03	ENST00000374510.8 ENST00000374507.4 ENST00000423740.7 ENST00000374511.7	TXNDC8 Ensembl NCBI GeneCards UniProt Show fit	thioredoxin domain containing 8
chr17_+_20579724 Show fit	1.02	ENST00000661883.1 ENST00000399044.1	CDRT15L2 Ensembl NCBI GeneCards UniProt Show fit	CMT1A duplicated region transcript 15 like 2
chr8_-_63026179 Show fit	1.02	ENST00000677919.1	GGH Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyl hydrolase
chr1_+_159802346 Show fit	1.02	ENST00000368106.4 ENST00000339348.9 ENST00000392235.7	FCRL6 Ensembl NCBI GeneCards UniProt Show fit	Fc receptor like 6
chr3_+_108822759 Show fit	1.01	ENST00000426646.1	TRAT1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor associated transmembrane adaptor 1
chr5_+_169695135 Show fit	1.00	ENST00000523684.5 ENST00000519734.5	DOCK2 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 2
chr2_-_88992903 Show fit	1.00	ENST00000495489.1	IGKV1-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-8
chr20_-_1491407 Show fit	1.00	ENST00000359801.8	SIRPB2 Ensembl NCBI GeneCards UniProt Show fit	signal regulatory protein beta 2
chr19_+_45864318 Show fit	1.00	ENST00000302177.3	FOXA3 Ensembl NCBI GeneCards UniProt Show fit	forkhead box A3
chr2_-_159798234 Show fit	0.98	ENST00000429078.6 ENST00000553424.5	CD302 Ensembl NCBI GeneCards UniProt Show fit	CD302 molecule
chr5_-_135954962 Show fit	0.97	ENST00000522943.5 ENST00000514447.2 ENST00000274507.6	LECT2 Ensembl NCBI GeneCards UniProt Show fit	leukocyte cell derived chemotaxin 2
chr12_+_1691011 Show fit	0.96	ENST00000357103.5	ADIPOR2 Ensembl NCBI GeneCards UniProt Show fit	adiponectin receptor 2
chrX_-_66040072 Show fit	0.96	ENST00000374737.9	VSIG4 Ensembl NCBI GeneCards UniProt Show fit	V-set and immunoglobulin domain containing 4
chr7_+_142563730 Show fit	0.95	ENST00000617347.1	TRBV12-4 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 12-4
chr2_-_159798043 Show fit	0.95	ENST00000664982.1 ENST00000259053.6	ENSG00000287091.1 Ensembl NCBI GeneCards UniProt Show fit CD302 Ensembl NCBI GeneCards UniProt Show fit	novel transcript, sense intronic to CD302and LY75-CD302 CD302 molecule
chrX_-_132218124 Show fit	0.94	ENST00000342983.6	RAP2C Ensembl NCBI GeneCards UniProt Show fit	RAP2C, member of RAS oncogene family
chrX_+_23908006 Show fit	0.94	ENST00000379211.8 ENST00000648352.1	CXorf58 Ensembl NCBI GeneCards UniProt Show fit	chromosome X open reading frame 58
chr5_+_149141483 Show fit	0.94	ENST00000326685.11 ENST00000309868.12	ABLIM3 Ensembl NCBI GeneCards UniProt Show fit	actin binding LIM protein family member 3
chr14_-_20587962 Show fit	0.93	ENST00000557105.5 ENST00000398008.6 ENST00000620912.4 ENST00000555841.5 ENST00000443456.6 ENST00000432835.6 ENST00000557503.5 ENST00000398009.6 ENST00000554842.1	RNASE11 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 11 (inactive)
chr14_-_106411021 Show fit	0.93	ENST00000390618.2	IGHV3-38 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3-38 (non-functional)
chr16_+_55478830 Show fit	0.93	ENST00000568715.5	MMP2 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 2
chr20_+_56533246 Show fit	0.92	ENST00000371325.1	FAM209B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 209 member B
chrX_-_66040057 Show fit	0.91	ENST00000412866.2	VSIG4 Ensembl NCBI GeneCards UniProt Show fit	V-set and immunoglobulin domain containing 4
chr9_-_98192614 Show fit	0.91	ENST00000375077.5	CORO2A Ensembl NCBI GeneCards UniProt Show fit	coronin 2A
chr11_+_125746272 Show fit	0.90	ENST00000305738.10 ENST00000437148.2	PATE1 Ensembl NCBI GeneCards UniProt Show fit	prostate and testis expressed 1
chr7_+_80646436 Show fit	0.88	ENST00000419819.2	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr8_+_22367259 Show fit	0.88	ENST00000520644.1 ENST00000359741.10 ENST00000381237.6 ENST00000240095.10	SLC39A14 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 14
chr19_-_51501755 Show fit	0.85	ENST00000291707.8	SIGLEC12 Ensembl NCBI GeneCards UniProt Show fit	sialic acid binding Ig like lectin 12
chr12_-_7695752 Show fit	0.85	ENST00000329913.4	GDF3 Ensembl NCBI GeneCards UniProt Show fit	growth differentiation factor 3
chr3_-_42410558 Show fit	0.83	ENST00000441172.1 ENST00000287748.8	LYZL4 Ensembl NCBI GeneCards UniProt Show fit	lysozyme like 4
chr7_+_150567382 Show fit	0.82	ENST00000255945.4 ENST00000479232.1	GIMAP4 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 4
chr4_+_122379508 Show fit	0.82	ENST00000388725.2	ADAD1 Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase domain containing 1
chrX_+_151716068 Show fit	0.81	ENST00000417321.1	FATE1 Ensembl NCBI GeneCards UniProt Show fit	fetal and adult testis expressed 1
chr1_+_172659095 Show fit	0.79	ENST00000367721.3 ENST00000340030.4	FASLG Ensembl NCBI GeneCards UniProt Show fit	Fas ligand
chr2_-_208255055 Show fit	0.79	ENST00000345146.7	IDH1 Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NADP(+)) 1
chr7_+_150737382 Show fit	0.79	ENST00000358647.5	GIMAP5 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 5
chr6_-_32853618 Show fit	0.78	ENST00000354258.5	TAP1 Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr14_+_21965451 Show fit	0.78	ENST00000390442.3	TRAV12-3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 12-3
chr6_+_32854179 Show fit	0.78	ENST00000374859.3	PSMB9 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr7_+_150567347 Show fit	0.77	ENST00000461940.5	GIMAP4 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 4
chr1_+_167630093 Show fit	0.77	ENST00000537350.5 ENST00000361496.3 ENST00000367854.8	RCSD1 Ensembl NCBI GeneCards UniProt Show fit	RCSD domain containing 1
chr21_-_14546351 Show fit	0.76	ENST00000619120.4	SAMSN1 Ensembl NCBI GeneCards UniProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr20_+_142573 Show fit	0.75	ENST00000382398.4	DEFB126 Ensembl NCBI GeneCards UniProt Show fit	defensin beta 126
chr2_+_202073249 Show fit	0.74	ENST00000498697.3	KIAA2012 Ensembl NCBI GeneCards UniProt Show fit	KIAA2012
chr14_+_21723693 Show fit	0.74	ENST00000390425.2	TRAV3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 3
chr11_-_105023136 Show fit	0.73	ENST00000526056.5 ENST00000531367.5 ENST00000456094.1 ENST00000444749.6 ENST00000393141.6 ENST00000418434.5 ENST00000260315.8	CASP5 Ensembl NCBI GeneCards UniProt Show fit	caspase 5
chr4_-_79326008 Show fit	0.73	ENST00000286794.5	NAA11 Ensembl NCBI GeneCards UniProt Show fit	N-alpha-acetyltransferase 11, NatA catalytic subunit
chr17_+_55751021 Show fit	0.73	ENST00000268896.10 ENST00000576183.5 ENST00000573500.5	PCTP Ensembl NCBI GeneCards UniProt Show fit	phosphatidylcholine transfer protein
chr17_-_14236862 Show fit	0.73	ENST00000420162.7 ENST00000431716.2	CDRT15 Ensembl NCBI GeneCards UniProt Show fit	CMT1A duplicated region transcript 15
chr11_+_59172116 Show fit	0.72	ENST00000227451.4	DTX4 Ensembl NCBI GeneCards UniProt Show fit	deltex E3 ubiquitin ligase 4
chr1_+_151047699 Show fit	0.71	ENST00000368926.6	C1orf56 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 56
chr9_+_273026 Show fit	0.69	ENST00000682249.1 ENST00000453981.5 ENST00000487230.5 ENST00000469391.5	DOCK8 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 8
chr6_+_42155399 Show fit	0.69	ENST00000623004.2 ENST00000372963.4 ENST00000654459.1	GUCA1ANB Ensembl NCBI GeneCards UniProt Show fit GUCA1A Ensembl NCBI GeneCards UniProt Show fit	GUCA1A neighbor guanylate cyclase activator 1A
chr16_+_55479188 Show fit	0.69	ENST00000219070.9	MMP2 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 2
chr8_-_120812848 Show fit	0.68	ENST00000520717.1	SNTB1 Ensembl NCBI GeneCards UniProt Show fit	syntrophin beta 1
chr1_+_196888014 Show fit	0.68	ENST00000367416.6 ENST00000608469.6 ENST00000251424.8 ENST00000367418.2	CFHR4 Ensembl NCBI GeneCards UniProt Show fit	complement factor H related 4
chr14_+_89956523 Show fit	0.66	ENST00000553989.1	TDP1 Ensembl NCBI GeneCards UniProt Show fit	tyrosyl-DNA phosphodiesterase 1
chr22_+_24495242 Show fit	0.66	ENST00000382760.2 ENST00000326010.10	UPB1 Ensembl NCBI GeneCards UniProt Show fit	beta-ureidopropionase 1
chr1_+_162381703 Show fit	0.63	ENST00000458626.4	C1orf226 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 226
chr16_+_33009175 Show fit	0.63	ENST00000565407.2	IGHV3OR16-8 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr11_+_7485606 Show fit	0.63	ENST00000528758.1	OLFML1 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin like 1
chr4_+_177309866 Show fit	0.62	ENST00000264596.4	NEIL3 Ensembl NCBI GeneCards UniProt Show fit	nei like DNA glycosylase 3
chr14_+_21317535 Show fit	0.62	ENST00000382933.8	RPGRIP1 Ensembl NCBI GeneCards UniProt Show fit	RPGR interacting protein 1
chr17_-_31318818 Show fit	0.62	ENST00000578584.5	ENSG00000265118.5 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr21_-_44920918 Show fit	0.61	ENST00000522688.5	ITGB2 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 2
chr7_-_151024423 Show fit	0.61	ENST00000469530.4 ENST00000639579.1	ATG9B Ensembl NCBI GeneCards UniProt Show fit	autophagy related 9B
chr11_+_7485492 Show fit	0.61	ENST00000534244.1 ENST00000329293.4	OLFML1 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin like 1
chr15_-_74725370 Show fit	0.61	ENST00000567032.5 ENST00000564596.5 ENST00000566503.1 ENST00000395049.8 ENST00000379727.8 ENST00000617691.4 ENST00000395048.6	CYP1A1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 1 subfamily A member 1
chr17_-_57745292 Show fit	0.61	ENST00000299415.3	CCDC182 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 182
chr5_+_119629552 Show fit	0.60	ENST00000613773.4 ENST00000620555.4 ENST00000515256.5 ENST00000509264.1	FAM170A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 170 member A
chr15_-_50119215 Show fit	0.60	ENST00000284509.11 ENST00000674213.1	ATP8B4 Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 8B4 (putative)
chr2_+_149118169 Show fit	0.59	ENST00000450639.5	LYPD6B Ensembl NCBI GeneCards UniProt Show fit	LY6/PLAUR domain containing 6B
chr1_-_183590876 Show fit	0.59	ENST00000367536.5	NCF2 Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 2
chr3_-_179266971 Show fit	0.59	ENST00000349697.2 ENST00000497599.5	KCNMB3 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr7_-_150978284 Show fit	0.59	ENST00000262186.10	KCNH2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily H member 2
chr19_-_51027662 Show fit	0.59	ENST00000594768.5	KLK11 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 11
chr11_+_18412292 Show fit	0.58	ENST00000541669.6 ENST00000280704.8	LDHC Ensembl NCBI GeneCards UniProt Show fit	lactate dehydrogenase C
chr1_+_159800503 Show fit	0.58	ENST00000536257.5 ENST00000321935.10	FCRL6 Ensembl NCBI GeneCards UniProt Show fit	Fc receptor like 6
chr19_+_48900305 Show fit	0.56	ENST00000405315.9 ENST00000407032.5 ENST00000452087.5 ENST00000411700.5	NUCB1 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 1
chr19_+_48019726 Show fit	0.55	ENST00000593413.1	ELSPBP1 Ensembl NCBI GeneCards UniProt Show fit	epididymal sperm binding protein 1
chr8_-_81531378 Show fit	0.53	ENST00000360464.4	FABP12 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 12
chr2_-_23927107 Show fit	0.52	ENST00000238789.10	ATAD2B Ensembl NCBI GeneCards UniProt Show fit	ATPase family AAA domain containing 2B
chr10_+_69801874 Show fit	0.52	ENST00000357811.8	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chrX_+_44844015 Show fit	0.51	ENST00000339042.6	DUSP21 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 21
chrX_+_22272913 Show fit	0.49	ENST00000323684.4	CBLL2 Ensembl NCBI GeneCards UniProt Show fit	Cbl proto-oncogene like 2
chr5_-_138274610 Show fit	0.49	ENST00000274721.8	GFRA3 Ensembl NCBI GeneCards UniProt Show fit	GDNF family receptor alpha 3
chr14_+_30874745 Show fit	0.49	ENST00000556908.5 ENST00000555881.5 ENST00000460581.6 ENST00000643575.1	COCH Ensembl NCBI GeneCards UniProt Show fit	cochlin
chr21_+_46286623 Show fit	0.49	ENST00000397691.1	YBEY Ensembl NCBI GeneCards UniProt Show fit	ybeY metalloendoribonuclease
chr19_-_51028015 Show fit	0.48	ENST00000319720.11	KLK11 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 11
chr16_+_2026834 Show fit	0.48	ENST00000424542.7 ENST00000432365.6	SLC9A3R2 Ensembl NCBI GeneCards UniProt Show fit	SLC9A3 regulator 2
chr20_-_1491474 Show fit	0.47	ENST00000444444.2	SIRPB2 Ensembl NCBI GeneCards UniProt Show fit	signal regulatory protein beta 2
chr7_+_100373458 Show fit	0.47	ENST00000453419.5 ENST00000198536.7 ENST00000394000.6 ENST00000350573.2	PILRA Ensembl NCBI GeneCards UniProt Show fit	paired immunoglobin like type 2 receptor alpha
chr15_-_73368951 Show fit	0.47	ENST00000261917.4	HCN4 Ensembl NCBI GeneCards UniProt Show fit	hyperpolarization activated cyclic nucleotide gated potassium channel 4
chr20_+_38581186 Show fit	0.46	ENST00000373348.4 ENST00000537425.2 ENST00000416116.2	ADIG Ensembl NCBI GeneCards UniProt Show fit	adipogenin
chr11_-_78139258 Show fit	0.46	ENST00000530910.6 ENST00000681417.1 ENST00000681225.1 ENST00000681765.1 ENST00000525870.6 ENST00000530608.6 ENST00000532306.6 ENST00000376156.7 ENST00000681699.1 ENST00000681221.1 ENST00000679444.1 ENST00000680829.1 ENST00000680761.1 ENST00000680256.1 ENST00000525783.6 ENST00000529139.6 ENST00000680580.1 ENST00000526849.6 ENST00000680399.1 ENST00000527099.2 ENST00000681489.1 ENST00000299626.10 ENST00000679497.1 ENST00000680101.1 ENST00000532440.6 ENST00000530454.6 ENST00000525761.3 ENST00000681575.1 ENST00000679559.1 ENST00000680398.1 ENST00000615266.5 ENST00000680643.1	ALG8 Ensembl NCBI GeneCards UniProt Show fit	ALG8 alpha-1,3-glucosyltransferase
chr8_-_132111159 Show fit	0.45	ENST00000673615.1 ENST00000434736.6	HHLA1 Ensembl NCBI GeneCards UniProt Show fit	HERV-H LTR-associating 1
chrX_+_125320120 Show fit	0.44	ENST00000632600.1	TEX13C Ensembl NCBI GeneCards UniProt Show fit	TEX13 family member C
chr17_+_76376581 Show fit	0.44	ENST00000591651.5 ENST00000545180.5	SPHK1 Ensembl NCBI GeneCards UniProt Show fit	sphingosine kinase 1
chr12_+_10929229 Show fit	0.44	ENST00000381847.7 ENST00000396400.4	PRH2 Ensembl NCBI GeneCards UniProt Show fit	proline rich protein HaeIII subfamily 2
chr5_-_138274565 Show fit	0.44	ENST00000378362.3	GFRA3 Ensembl NCBI GeneCards UniProt Show fit	GDNF family receptor alpha 3
chr8_-_138914034 Show fit	0.43	ENST00000303045.11	COL22A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XXII alpha 1 chain
chrX_-_71618455 Show fit	0.42	ENST00000373691.4 ENST00000373693.4	CXCR3 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine receptor 3
chr19_+_51251272 Show fit	0.42	ENST00000596117.5	SIGLECL1 Ensembl NCBI GeneCards UniProt Show fit	SIGLEC family like 1
chrX_-_149549924 Show fit	0.41	ENST00000431993.4	HSFX3 Ensembl NCBI GeneCards UniProt Show fit	heat shock transcription factor family, X-linked member 3
chr19_-_10568968 Show fit	0.41	ENST00000393599.3	CDKN2D Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 2D
chr5_-_160312756 Show fit	0.41	ENST00000644313.1	CCNJL Ensembl NCBI GeneCards UniProt Show fit	cyclin J like
chr7_+_76478127 Show fit	0.39	ENST00000435861.1	DTX2 Ensembl NCBI GeneCards UniProt Show fit	deltex E3 ubiquitin ligase 2
chr8_-_71356653 Show fit	0.39	ENST00000388742.8 ENST00000388740.4	EYA1 Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 1
chr19_-_51027954 Show fit	0.39	ENST00000391804.7	KLK11 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 11
chr5_-_39424859 Show fit	0.39	ENST00000503513.5	DAB2 Ensembl NCBI GeneCards UniProt Show fit	DAB adaptor protein 2
chr3_-_121545962 Show fit	0.38	ENST00000264233.6	POLQ Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase theta
chr19_+_58387260 Show fit	0.37	ENST00000598098.5 ENST00000598495.5 ENST00000196551.8 ENST00000596046.1	RPS5 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S5
chr9_-_127916978 Show fit	0.37	ENST00000361444.3 ENST00000335791.10	ST6GALNAC4 Ensembl NCBI GeneCards UniProt Show fit	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr22_-_41285868 Show fit	0.37	ENST00000422838.1 ENST00000405486.5	RANGAP1 Ensembl NCBI GeneCards UniProt Show fit	Ran GTPase activating protein 1
chr8_-_71356511 Show fit	0.36	ENST00000419131.6 ENST00000388743.6	EYA1 Ensembl NCBI GeneCards UniProt Show fit	EYA transcriptional coactivator and phosphatase 1
chr19_-_10569022 Show fit	0.36	ENST00000335766.2	CDKN2D Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 2D
chr15_-_34343112 Show fit	0.35	ENST00000557912.1 ENST00000328848.6	NOP10 Ensembl NCBI GeneCards UniProt Show fit	NOP10 ribonucleoprotein
chr19_+_48900798 Show fit	0.35	ENST00000424608.1	NUCB1 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 1
chr3_+_148730100 Show fit	0.35	ENST00000474935.5 ENST00000475347.5 ENST00000461609.1	AGTR1 Ensembl NCBI GeneCards UniProt Show fit	angiotensin II receptor type 1
chr7_-_113086369 Show fit	0.34	ENST00000449735.1 ENST00000438062.5	GPR85 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 85
chr19_-_51034840 Show fit	0.34	ENST00000529888.5	KLK12 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 12
chr19_-_47803558 Show fit	0.34	ENST00000543508.1 ENST00000322175.7	TPRX1 Ensembl NCBI GeneCards UniProt Show fit	tetrapeptide repeat homeobox 1
chr1_-_153963262 Show fit	0.34	ENST00000417348.2	SLC39A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 1
chr4_-_184649436 Show fit	0.33	ENST00000308394.9 ENST00000517513.5 ENST00000447121.2 ENST00000393588.8 ENST00000523916.5	CASP3 Ensembl NCBI GeneCards UniProt Show fit	caspase 3
chr9_-_92536645 Show fit	0.33	ENST00000395534.2	ECM2 Ensembl NCBI GeneCards UniProt Show fit	extracellular matrix protein 2
chr1_-_9910310 Show fit	0.33	ENST00000400904.7	CTNNBIP1 Ensembl NCBI GeneCards UniProt Show fit	catenin beta interacting protein 1
chr22_+_26621952 Show fit	0.32	ENST00000354760.4	CRYBA4 Ensembl NCBI GeneCards UniProt Show fit	crystallin beta A4
chr14_+_22207502 Show fit	0.32	ENST00000390461.2	TRAV34 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 34
chr14_-_20609773 Show fit	0.32	ENST00000555283.1 ENST00000413502.1	ENSG00000259060.7 Ensembl NCBI GeneCards UniProt Show fit RNASE11 Ensembl NCBI GeneCards UniProt Show fit	novel protein ribonuclease A family member 11 (inactive)
chr19_+_54816468 Show fit	0.32	ENST00000391728.8 ENST00000326542.11 ENST00000358178.4	KIR3DL1 Ensembl NCBI GeneCards UniProt Show fit	killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
chr19_-_51034892 Show fit	0.32	ENST00000319590.8 ENST00000250351.4	KLK12 Ensembl NCBI GeneCards UniProt Show fit	kallikrein related peptidase 12
chr5_-_39424966 Show fit	0.31	ENST00000515700.5 ENST00000320816.11 ENST00000339788.10	DAB2 Ensembl NCBI GeneCards UniProt Show fit	DAB adaptor protein 2
chr6_-_43059367 Show fit	0.30	ENST00000230413.9 ENST00000487429.1 ENST00000388752.8 ENST00000489623.1 ENST00000468957.1	MRPL2 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L2
chr11_+_71833200 Show fit	0.30	ENST00000328698.2	DEFB108B Ensembl NCBI GeneCards UniProt Show fit	defensin beta 108B
chr22_+_24603147 Show fit	0.28	ENST00000412658.5 ENST00000445029.5 ENST00000400382.6 ENST00000419133.5 ENST00000438643.6 ENST00000452551.5 ENST00000412898.5 ENST00000400380.5 ENST00000455483.5 ENST00000430289.5	GGT1 Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyltransferase 1
chr17_+_49210387 Show fit	0.28	ENST00000419580.6	ABI3 Ensembl NCBI GeneCards UniProt Show fit	ABI family member 3
chr19_-_38878247 Show fit	0.28	ENST00000591812.2	RINL Ensembl NCBI GeneCards UniProt Show fit	Ras and Rab interactor like
chr12_+_16347665 Show fit	0.27	ENST00000535309.5 ENST00000540056.5 ENST00000396209.5 ENST00000540126.5	MGST1 Ensembl NCBI GeneCards UniProt Show fit	microsomal glutathione S-transferase 1
chr2_-_23927048 Show fit	0.27	ENST00000439915.1	ATAD2B Ensembl NCBI GeneCards UniProt Show fit	ATPase family AAA domain containing 2B
chr12_+_48482492 Show fit	0.27	ENST00000548364.7	C12orf54 Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 54
chr6_-_46735693 Show fit	0.26	ENST00000537365.1	PLA2G7 Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group VII
chr1_+_162631946 Show fit	0.26	ENST00000671979.1	DDR2 Ensembl NCBI GeneCards UniProt Show fit	discoidin domain receptor tyrosine kinase 2
chr6_+_33080445 Show fit	0.26	ENST00000428835.5	HLA-DPB1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr4_+_102869332 Show fit	0.25	ENST00000503643.1	CISD2 Ensembl NCBI GeneCards UniProt Show fit	CDGSH iron sulfur domain 2
chr2_-_216081759 Show fit	0.25	ENST00000265322.8	PECR Ensembl NCBI GeneCards UniProt Show fit	peroxisomal trans-2-enoyl-CoA reductase
chr12_+_12070932 Show fit	0.24	ENST00000308721.9	BCL2L14 Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 14
chr20_+_17969034 Show fit	0.24	ENST00000377709.1 ENST00000377704.4	MGME1 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial genome maintenance exonuclease 1
chr16_+_83899079 Show fit	0.24	ENST00000262430.6	MLYCD Ensembl NCBI GeneCards UniProt Show fit	malonyl-CoA decarboxylase
chr6_+_159800249 Show fit	0.24	ENST00000610273.5 ENST00000392167.4	PNLDC1 Ensembl NCBI GeneCards UniProt Show fit	PARN like, ribonuclease domain containing 1
chr12_+_16347637 Show fit	0.23	ENST00000543076.5 ENST00000396210.8	MGST1 Ensembl NCBI GeneCards UniProt Show fit	microsomal glutathione S-transferase 1
chr10_+_92848461 Show fit	0.23	ENST00000443748.6 ENST00000371543.5 ENST00000260762.10	EXOC6 Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 6
chr17_+_40309161 Show fit	0.23	ENST00000254066.10	RARA Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor alpha
chr3_+_63652695 Show fit	0.23	ENST00000496807.1	SNTN Ensembl NCBI GeneCards UniProt Show fit	sentan, cilia apical structure protein
chr3_+_119147375 Show fit	0.23	ENST00000490594.2	ENSG00000251012.2 Ensembl NCBI GeneCards UniProt Show fit	novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr14_+_21317547 Show fit	0.22	ENST00000557351.1	RPGRIP1 Ensembl NCBI GeneCards UniProt Show fit	RPGR interacting protein 1
chr2_+_202073282 Show fit	0.22	ENST00000459709.5	KIAA2012 Ensembl NCBI GeneCards UniProt Show fit	KIAA2012
chrX_-_149631787 Show fit	0.22	ENST00000600449.8 ENST00000611119.4	TMEM185A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 185A

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.5	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.8	2.5	GO:0006097	glyoxylate cycle(GO:0006097)
0.7	2.9	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6	1.9	GO:0046967	cytosol to ER transport(GO:0046967)
0.4	3.6	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3	2.1	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.3	2.2	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2	0.7	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2	0.7	GO:0061485	memory T cell proliferation(GO:0061485)
0.2	0.7	GO:0019483	beta-alanine biosynthetic process(GO:0019483)
0.2	1.0	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2	0.6	GO:0043449	cellular alkene metabolic process(GO:0043449)
0.2	0.6	GO:0003064	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2	0.9	GO:0035026	leading edge cell differentiation(GO:0035026)
0.2	0.5	GO:0071449	cellular response to lipid hydroperoxide(GO:0071449)
0.2	1.0	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
0.2	0.8	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2	0.8	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	1.6	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.4	GO:0046521	sphingoid catabolic process(GO:0046521)
0.1	0.9	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.6	GO:0019249	lactate biosynthetic process(GO:0019249)
0.1	1.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	2.8	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.7	GO:0070269	pyroptosis(GO:0070269)
0.1	0.6	GO:0044805	late nucleophagy(GO:0044805)
0.1	8.5	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	1.9	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.4	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1	0.3	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	2.9	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	1.0	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.1	1.0	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.1	0.2	GO:0015938	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1	0.4	GO:1904116	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1	0.8	GO:0048102	autophagic cell death(GO:0048102)
0.1	0.4	GO:0002528	regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1	1.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.9	GO:0072718	response to cisplatin(GO:0072718)
0.1	0.1	GO:0010157	response to chlorate(GO:0010157)
0.1	0.2	GO:1903173	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1	0.9	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.6	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	0.3	GO:2001153	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0	0.2	GO:0010446	response to alkaline pH(GO:0010446)
0.0	0.8	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:1990172	CVT pathway(GO:0032258) G-protein coupled receptor catabolic process(GO:1990172)
0.0	0.2	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.0	0.3	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.0	1.7	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	1.1	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.9	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.3	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0	0.7	GO:0000012	single strand break repair(GO:0000012)
0.0	0.7	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.9	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	3.4	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.2	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0	0.5	GO:0071321	cellular response to cGMP(GO:0071321)
0.0	1.8	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	1.6	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.4	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	3.4	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.2	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0	1.8	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	1.4	GO:0007099	centriole replication(GO:0007099)
0.0	0.2	GO:0097327	response to antineoplastic agent(GO:0097327)
0.0	0.1	GO:0060981	cell migration involved in coronary angiogenesis(GO:0060981)
0.0	2.3	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:0090669	telomerase RNA stabilization(GO:0090669)
0.0	0.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	4.4	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.3	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.7	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.1	GO:0032252	secretory granule localization(GO:0032252)
0.0	1.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.4	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.9	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.6	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0090625	mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0	1.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.5	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.3	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.6	GO:0006284	base-excision repair(GO:0006284)
0.0	0.2	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.7	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.5	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.1	GO:0015811	L-cystine transport(GO:0015811)
0.0	0.8	GO:0003009	skeletal muscle contraction(GO:0003009)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.5	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.3	1.9	GO:0042825	TAP complex(GO:0042825)
0.2	3.9	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.2	1.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.2	0.5	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2	0.9	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	7.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	1.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.7	GO:0072557	IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.1	0.5	GO:0098855	HCN channel complex(GO:0098855)
0.1	0.6	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	0.9	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.8	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.8	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.1	0.4	GO:1990723	cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1	0.7	GO:0031415	NatA complex(GO:0031415)
0.1	1.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	0.6	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.1	2.1	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.6	GO:0032010	phagolysosome(GO:0032010)
0.1	0.4	GO:0072589	box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.5	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	1.4	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.8	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	3.5	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.1	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0	0.2	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	4.0	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.7	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	1.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.6	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	1.6	GO:0031672	A band(GO:0031672)
0.0	1.9	GO:0036126	sperm flagellum(GO:0036126)
0.0	0.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.3	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.7	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	5.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.3	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.4	GO:0030877	beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	8.4	GO:0030492	hemoglobin binding(GO:0030492)
0.8	2.5	GO:0051990	isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.8	2.4	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.3	1.6	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.2	2.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.2	0.7	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2	1.0	GO:0055100	adiponectin binding(GO:0055100)
0.2	1.9	GO:0046979	MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.2	2.2	GO:0019863	IgE binding(GO:0019863)
0.2	0.7	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1	1.8	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.6	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.3	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	0.5	GO:0004583	alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1	0.3	GO:0016005	phospholipase A2 activator activity(GO:0016005)
0.1	1.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	7.6	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	1.0	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.1	0.7	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1	1.4	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.2	GO:0019166	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	0.9	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	2.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.9	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.1	0.9	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	2.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	0.3	GO:0032396	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.1	1.0	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.5	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	0.6	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	0.6	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.1	0.4	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	0.6	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	2.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.6	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.8	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.4	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.2	GO:0032440	2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0	0.6	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	1.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	7.7	GO:0003823	antigen binding(GO:0003823)
0.0	0.4	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.8	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.9	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	1.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.3	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0070736	protein-glycine ligase activity, initiating(GO:0070736)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.5	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.8	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.5	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	1.9	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	7.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.8	GO:0005123	death receptor binding(GO:0005123)
0.0	0.4	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.3	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.7	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.6	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0005019	platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0	0.2	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0	0.8	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	1.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	ST STAT3 PATHWAY	STAT3 Pathway
0.0	2.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.6	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	2.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	2.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	1.0	PID HNF3A PATHWAY	FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	2.5	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	1.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	2.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.7	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	2.4	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.0	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.3	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin

Results for TBX3

Z-value: 0.98

Motif logo

Transcription factors associated with TBX3

Activity-expression correlation:

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: