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Illumina Body Map 2 (GSE30611)

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Results for TBX3

Z-value: 0.98

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Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
ENSG00000135111.16 T-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg38_v1_chr12_-_114684151_114684221-0.183.3e-01Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_72054477 4.52 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr16_+_72063226 3.92 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
haptoglobin-related protein
chr3_+_149474688 3.41 ENST00000305354.5
ENST00000465758.1
transmembrane 4 L six family member 4
chr13_-_46105009 2.95 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr4_-_83109843 2.80 ENST00000411416.6
placenta associated 8
chr5_+_55024250 2.50 ENST00000231009.3
granzyme K
chr2_+_113117889 2.42 ENST00000361779.7
ENST00000259206.9
ENST00000354115.6
interleukin 1 receptor antagonist
chr2_-_88857582 2.31 ENST00000390237.2
immunoglobulin kappa constant
chr22_+_22895368 2.09 ENST00000390321.2
immunoglobulin lambda constant 1
chr17_-_7114240 1.97 ENST00000446679.6
asialoglycoprotein receptor 2
chr14_-_106360320 1.73 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr2_-_208254232 1.70 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chrX_-_132489015 1.70 ENST00000421707.1
ENST00000370853.8
muscleblind like splicing regulator 3
chr14_-_106005574 1.66 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr22_+_22720615 1.64 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr14_-_94452766 1.64 ENST00000334708.4
serpin family A member 11
chr20_+_58150896 1.63 ENST00000371168.4
chromosome 20 open reading frame 85
chr17_+_47209035 1.62 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr7_+_142345412 1.61 ENST00000390392.3
T cell receptor beta variable 4-2
chr4_+_154563003 1.59 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr11_-_10568571 1.51 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_+_142740206 1.46 ENST00000422143.2
T cell receptor beta variable 29-1
chr19_+_36100593 1.43 ENST00000680211.1
WD repeat domain 62
chr11_-_10568650 1.42 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr14_+_22007503 1.27 ENST00000390447.3
T cell receptor alpha variable 19
chr4_+_40193642 1.25 ENST00000617441.4
ENST00000503941.5
ras homolog family member H
chr22_+_22811737 1.22 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr9_-_34729482 1.18 ENST00000378788.4
family with sequence similarity 205 member A
chr7_+_22727147 1.17 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr19_+_1077394 1.16 ENST00000590577.2
Rho GTPase activating protein 45
chr1_+_212035717 1.16 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr2_-_89010515 1.14 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr3_+_108822778 1.13 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr6_-_32853813 1.13 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr19_-_7702139 1.13 ENST00000346664.9
Fc fragment of IgE receptor II
chr3_+_52420955 1.11 ENST00000465863.1
PHD finger protein 7
chr11_+_78063851 1.10 ENST00000281030.2
thyroid hormone responsive
chr2_+_90220727 1.09 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chr17_+_55751378 1.08 ENST00000325214.10
phosphatidylcholine transfer protein
chr19_-_7702124 1.08 ENST00000597921.6
Fc fragment of IgE receptor II
chr21_-_14546297 1.05 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr12_+_7062583 1.05 ENST00000542978.1
complement C1s
chr12_+_57455266 1.05 ENST00000266646.3
inhibin subunit beta E
chr9_-_110337808 1.03 ENST00000374510.8
ENST00000374507.4
ENST00000423740.7
ENST00000374511.7
thioredoxin domain containing 8
chr17_+_20579724 1.02 ENST00000661883.1
ENST00000399044.1
CMT1A duplicated region transcript 15 like 2
chr8_-_63026179 1.02 ENST00000677919.1
gamma-glutamyl hydrolase
chr1_+_159802346 1.02 ENST00000368106.4
ENST00000339348.9
ENST00000392235.7
Fc receptor like 6
chr3_+_108822759 1.01 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr5_+_169695135 1.00 ENST00000523684.5
ENST00000519734.5
dedicator of cytokinesis 2
chr2_-_88992903 1.00 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr20_-_1491407 1.00 ENST00000359801.8
signal regulatory protein beta 2
chr19_+_45864318 1.00 ENST00000302177.3
forkhead box A3
chr2_-_159798234 0.98 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr5_-_135954962 0.97 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr12_+_1691011 0.96 ENST00000357103.5
adiponectin receptor 2
chrX_-_66040072 0.96 ENST00000374737.9
V-set and immunoglobulin domain containing 4
chr7_+_142563730 0.95 ENST00000617347.1
T cell receptor beta variable 12-4
chr2_-_159798043 0.95 ENST00000664982.1
ENST00000259053.6
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chrX_-_132218124 0.94 ENST00000342983.6
RAP2C, member of RAS oncogene family
chrX_+_23908006 0.94 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr5_+_149141483 0.94 ENST00000326685.11
ENST00000309868.12
actin binding LIM protein family member 3
chr14_-_20587962 0.93 ENST00000557105.5
ENST00000398008.6
ENST00000620912.4
ENST00000555841.5
ENST00000443456.6
ENST00000432835.6
ENST00000557503.5
ENST00000398009.6
ENST00000554842.1
ribonuclease A family member 11 (inactive)
chr14_-_106411021 0.93 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr16_+_55478830 0.93 ENST00000568715.5
matrix metallopeptidase 2
chr20_+_56533246 0.92 ENST00000371325.1
family with sequence similarity 209 member B
chrX_-_66040057 0.91 ENST00000412866.2
V-set and immunoglobulin domain containing 4
chr9_-_98192614 0.91 ENST00000375077.5
coronin 2A
chr11_+_125746272 0.90 ENST00000305738.10
ENST00000437148.2
prostate and testis expressed 1
chr7_+_80646436 0.88 ENST00000419819.2
CD36 molecule
chr8_+_22367259 0.88 ENST00000520644.1
ENST00000359741.10
ENST00000381237.6
ENST00000240095.10
solute carrier family 39 member 14
chr19_-_51501755 0.85 ENST00000291707.8
sialic acid binding Ig like lectin 12
chr12_-_7695752 0.85 ENST00000329913.4
growth differentiation factor 3
chr3_-_42410558 0.83 ENST00000441172.1
ENST00000287748.8
lysozyme like 4
chr7_+_150567382 0.82 ENST00000255945.4
ENST00000479232.1
GTPase, IMAP family member 4
chr4_+_122379508 0.82 ENST00000388725.2
adenosine deaminase domain containing 1
chrX_+_151716068 0.81 ENST00000417321.1
fetal and adult testis expressed 1
chr1_+_172659095 0.79 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr2_-_208255055 0.79 ENST00000345146.7
isocitrate dehydrogenase (NADP(+)) 1
chr7_+_150737382 0.79 ENST00000358647.5
GTPase, IMAP family member 5
chr6_-_32853618 0.78 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr14_+_21965451 0.78 ENST00000390442.3
T cell receptor alpha variable 12-3
chr6_+_32854179 0.78 ENST00000374859.3
proteasome 20S subunit beta 9
chr7_+_150567347 0.77 ENST00000461940.5
GTPase, IMAP family member 4
chr1_+_167630093 0.77 ENST00000537350.5
ENST00000361496.3
ENST00000367854.8
RCSD domain containing 1
chr21_-_14546351 0.76 ENST00000619120.4
SAM domain, SH3 domain and nuclear localization signals 1
chr20_+_142573 0.75 ENST00000382398.4
defensin beta 126
chr2_+_202073249 0.74 ENST00000498697.3
KIAA2012
chr14_+_21723693 0.74 ENST00000390425.2
T cell receptor alpha variable 3
chr11_-_105023136 0.73 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr4_-_79326008 0.73 ENST00000286794.5
N-alpha-acetyltransferase 11, NatA catalytic subunit
chr17_+_55751021 0.73 ENST00000268896.10
ENST00000576183.5
ENST00000573500.5
phosphatidylcholine transfer protein
chr17_-_14236862 0.73 ENST00000420162.7
ENST00000431716.2
CMT1A duplicated region transcript 15
chr11_+_59172116 0.72 ENST00000227451.4
deltex E3 ubiquitin ligase 4
chr1_+_151047699 0.71 ENST00000368926.6
chromosome 1 open reading frame 56
chr9_+_273026 0.69 ENST00000682249.1
ENST00000453981.5
ENST00000487230.5
ENST00000469391.5
dedicator of cytokinesis 8
chr6_+_42155399 0.69 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1A neighbor
guanylate cyclase activator 1A
chr16_+_55479188 0.69 ENST00000219070.9
matrix metallopeptidase 2
chr8_-_120812848 0.68 ENST00000520717.1
syntrophin beta 1
chr1_+_196888014 0.68 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr14_+_89956523 0.66 ENST00000553989.1
tyrosyl-DNA phosphodiesterase 1
chr22_+_24495242 0.66 ENST00000382760.2
ENST00000326010.10
beta-ureidopropionase 1
chr1_+_162381703 0.63 ENST00000458626.4
chromosome 1 open reading frame 226
chr16_+_33009175 0.63 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr11_+_7485606 0.63 ENST00000528758.1
olfactomedin like 1
chr4_+_177309866 0.62 ENST00000264596.4
nei like DNA glycosylase 3
chr14_+_21317535 0.62 ENST00000382933.8
RPGR interacting protein 1
chr17_-_31318818 0.62 ENST00000578584.5
novel protein
chr21_-_44920918 0.61 ENST00000522688.5
integrin subunit beta 2
chr7_-_151024423 0.61 ENST00000469530.4
ENST00000639579.1
autophagy related 9B
chr11_+_7485492 0.61 ENST00000534244.1
ENST00000329293.4
olfactomedin like 1
chr15_-_74725370 0.61 ENST00000567032.5
ENST00000564596.5
ENST00000566503.1
ENST00000395049.8
ENST00000379727.8
ENST00000617691.4
ENST00000395048.6
cytochrome P450 family 1 subfamily A member 1
chr17_-_57745292 0.61 ENST00000299415.3
coiled-coil domain containing 182
chr5_+_119629552 0.60 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chr15_-_50119215 0.60 ENST00000284509.11
ENST00000674213.1
ATPase phospholipid transporting 8B4 (putative)
chr2_+_149118169 0.59 ENST00000450639.5
LY6/PLAUR domain containing 6B
chr1_-_183590876 0.59 ENST00000367536.5
neutrophil cytosolic factor 2
chr3_-_179266971 0.59 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr7_-_150978284 0.59 ENST00000262186.10
potassium voltage-gated channel subfamily H member 2
chr19_-_51027662 0.59 ENST00000594768.5
kallikrein related peptidase 11
chr11_+_18412292 0.58 ENST00000541669.6
ENST00000280704.8
lactate dehydrogenase C
chr1_+_159800503 0.58 ENST00000536257.5
ENST00000321935.10
Fc receptor like 6
chr19_+_48900305 0.56 ENST00000405315.9
ENST00000407032.5
ENST00000452087.5
ENST00000411700.5
nucleobindin 1
chr19_+_48019726 0.55 ENST00000593413.1
epididymal sperm binding protein 1
chr8_-_81531378 0.53 ENST00000360464.4
fatty acid binding protein 12
chr2_-_23927107 0.52 ENST00000238789.10
ATPase family AAA domain containing 2B
chr10_+_69801874 0.52 ENST00000357811.8
collagen type XIII alpha 1 chain
chrX_+_44844015 0.51 ENST00000339042.6
dual specificity phosphatase 21
chrX_+_22272913 0.49 ENST00000323684.4
Cbl proto-oncogene like 2
chr5_-_138274610 0.49 ENST00000274721.8
GDNF family receptor alpha 3
chr14_+_30874745 0.49 ENST00000556908.5
ENST00000555881.5
ENST00000460581.6
ENST00000643575.1
cochlin
chr21_+_46286623 0.49 ENST00000397691.1
ybeY metalloendoribonuclease
chr19_-_51028015 0.48 ENST00000319720.11
kallikrein related peptidase 11
chr16_+_2026834 0.48 ENST00000424542.7
ENST00000432365.6
SLC9A3 regulator 2
chr20_-_1491474 0.47 ENST00000444444.2
signal regulatory protein beta 2
chr7_+_100373458 0.47 ENST00000453419.5
ENST00000198536.7
ENST00000394000.6
ENST00000350573.2
paired immunoglobin like type 2 receptor alpha
chr15_-_73368951 0.47 ENST00000261917.4
hyperpolarization activated cyclic nucleotide gated potassium channel 4
chr20_+_38581186 0.46 ENST00000373348.4
ENST00000537425.2
ENST00000416116.2
adipogenin
chr11_-_78139258 0.46 ENST00000530910.6
ENST00000681417.1
ENST00000681225.1
ENST00000681765.1
ENST00000525870.6
ENST00000530608.6
ENST00000532306.6
ENST00000376156.7
ENST00000681699.1
ENST00000681221.1
ENST00000679444.1
ENST00000680829.1
ENST00000680761.1
ENST00000680256.1
ENST00000525783.6
ENST00000529139.6
ENST00000680580.1
ENST00000526849.6
ENST00000680399.1
ENST00000527099.2
ENST00000681489.1
ENST00000299626.10
ENST00000679497.1
ENST00000680101.1
ENST00000532440.6
ENST00000530454.6
ENST00000525761.3
ENST00000681575.1
ENST00000679559.1
ENST00000680398.1
ENST00000615266.5
ENST00000680643.1
ALG8 alpha-1,3-glucosyltransferase
chr8_-_132111159 0.45 ENST00000673615.1
ENST00000434736.6
HERV-H LTR-associating 1
chrX_+_125320120 0.44 ENST00000632600.1
TEX13 family member C
chr17_+_76376581 0.44 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr12_+_10929229 0.44 ENST00000381847.7
ENST00000396400.4
proline rich protein HaeIII subfamily 2
chr5_-_138274565 0.44 ENST00000378362.3
GDNF family receptor alpha 3
chr8_-_138914034 0.43 ENST00000303045.11
collagen type XXII alpha 1 chain
chrX_-_71618455 0.42 ENST00000373691.4
ENST00000373693.4
C-X-C motif chemokine receptor 3
chr19_+_51251272 0.42 ENST00000596117.5
SIGLEC family like 1
chrX_-_149549924 0.41 ENST00000431993.4
heat shock transcription factor family, X-linked member 3
chr19_-_10568968 0.41 ENST00000393599.3
cyclin dependent kinase inhibitor 2D
chr5_-_160312756 0.41 ENST00000644313.1
cyclin J like
chr7_+_76478127 0.39 ENST00000435861.1
deltex E3 ubiquitin ligase 2
chr8_-_71356653 0.39 ENST00000388742.8
ENST00000388740.4
EYA transcriptional coactivator and phosphatase 1
chr19_-_51027954 0.39 ENST00000391804.7
kallikrein related peptidase 11
chr5_-_39424859 0.39 ENST00000503513.5
DAB adaptor protein 2
chr3_-_121545962 0.38 ENST00000264233.6
DNA polymerase theta
chr19_+_58387260 0.37 ENST00000598098.5
ENST00000598495.5
ENST00000196551.8
ENST00000596046.1
ribosomal protein S5
chr9_-_127916978 0.37 ENST00000361444.3
ENST00000335791.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr22_-_41285868 0.37 ENST00000422838.1
ENST00000405486.5
Ran GTPase activating protein 1
chr8_-_71356511 0.36 ENST00000419131.6
ENST00000388743.6
EYA transcriptional coactivator and phosphatase 1
chr19_-_10569022 0.36 ENST00000335766.2
cyclin dependent kinase inhibitor 2D
chr15_-_34343112 0.35 ENST00000557912.1
ENST00000328848.6
NOP10 ribonucleoprotein
chr19_+_48900798 0.35 ENST00000424608.1
nucleobindin 1
chr3_+_148730100 0.35 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr7_-_113086369 0.34 ENST00000449735.1
ENST00000438062.5
G protein-coupled receptor 85
chr19_-_51034840 0.34 ENST00000529888.5
kallikrein related peptidase 12
chr19_-_47803558 0.34 ENST00000543508.1
ENST00000322175.7
tetrapeptide repeat homeobox 1
chr1_-_153963262 0.34 ENST00000417348.2
solute carrier family 39 member 1
chr4_-_184649436 0.33 ENST00000308394.9
ENST00000517513.5
ENST00000447121.2
ENST00000393588.8
ENST00000523916.5
caspase 3
chr9_-_92536645 0.33 ENST00000395534.2
extracellular matrix protein 2
chr1_-_9910310 0.33 ENST00000400904.7
catenin beta interacting protein 1
chr22_+_26621952 0.32 ENST00000354760.4
crystallin beta A4
chr14_+_22207502 0.32 ENST00000390461.2
T cell receptor alpha variable 34
chr14_-_20609773 0.32 ENST00000555283.1
ENST00000413502.1
novel protein
ribonuclease A family member 11 (inactive)
chr19_+_54816468 0.32 ENST00000391728.8
ENST00000326542.11
ENST00000358178.4
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
chr19_-_51034892 0.32 ENST00000319590.8
ENST00000250351.4
kallikrein related peptidase 12
chr5_-_39424966 0.31 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr6_-_43059367 0.30 ENST00000230413.9
ENST00000487429.1
ENST00000388752.8
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr11_+_71833200 0.30 ENST00000328698.2
defensin beta 108B
chr22_+_24603147 0.28 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
gamma-glutamyltransferase 1
chr17_+_49210387 0.28 ENST00000419580.6
ABI family member 3
chr19_-_38878247 0.28 ENST00000591812.2
Ras and Rab interactor like
chr12_+_16347665 0.27 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
microsomal glutathione S-transferase 1
chr2_-_23927048 0.27 ENST00000439915.1
ATPase family AAA domain containing 2B
chr12_+_48482492 0.27 ENST00000548364.7
chromosome 12 open reading frame 54
chr6_-_46735693 0.26 ENST00000537365.1
phospholipase A2 group VII
chr1_+_162631946 0.26 ENST00000671979.1
discoidin domain receptor tyrosine kinase 2
chr6_+_33080445 0.26 ENST00000428835.5
major histocompatibility complex, class II, DP beta 1
chr4_+_102869332 0.25 ENST00000503643.1
CDGSH iron sulfur domain 2
chr2_-_216081759 0.25 ENST00000265322.8
peroxisomal trans-2-enoyl-CoA reductase
chr12_+_12070932 0.24 ENST00000308721.9
BCL2 like 14
chr20_+_17969034 0.24 ENST00000377709.1
ENST00000377704.4
mitochondrial genome maintenance exonuclease 1
chr16_+_83899079 0.24 ENST00000262430.6
malonyl-CoA decarboxylase
chr6_+_159800249 0.24 ENST00000610273.5
ENST00000392167.4
PARN like, ribonuclease domain containing 1
chr12_+_16347637 0.23 ENST00000543076.5
ENST00000396210.8
microsomal glutathione S-transferase 1
chr10_+_92848461 0.23 ENST00000443748.6
ENST00000371543.5
ENST00000260762.10
exocyst complex component 6
chr17_+_40309161 0.23 ENST00000254066.10
retinoic acid receptor alpha
chr3_+_63652695 0.23 ENST00000496807.1
sentan, cilia apical structure protein
chr3_+_119147375 0.23 ENST00000490594.2
novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr14_+_21317547 0.22 ENST00000557351.1
RPGR interacting protein 1
chr2_+_202073282 0.22 ENST00000459709.5
KIAA2012
chrX_-_149631787 0.22 ENST00000600449.8
ENST00000611119.4
transmembrane protein 185A

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.8 2.5 GO:0006097 glyoxylate cycle(GO:0006097)
0.7 2.9 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6 1.9 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 3.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 2.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 2.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 0.7 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 0.7 GO:0061485 memory T cell proliferation(GO:0061485)
0.2 0.7 GO:0019483 beta-alanine biosynthetic process(GO:0019483)
0.2 1.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.6 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.2 0.6 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2 0.9 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.2 1.0 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.2 0.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 0.8 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.6 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.9 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.6 GO:0019249 lactate biosynthetic process(GO:0019249)
0.1 1.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 2.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.7 GO:0070269 pyroptosis(GO:0070269)
0.1 0.6 GO:0044805 late nucleophagy(GO:0044805)
0.1 8.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 2.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.0 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.2 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.4 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.8 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.9 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.1 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1 0.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:1990172 CVT pathway(GO:0032258) G-protein coupled receptor catabolic process(GO:1990172)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 1.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.1 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.7 GO:0000012 single strand break repair(GO:0000012)
0.0 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 3.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.5 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 1.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 1.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 3.4 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 1.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 1.4 GO:0007099 centriole replication(GO:0007099)
0.0 0.2 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 2.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 4.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 1.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 1.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.8 GO:0003009 skeletal muscle contraction(GO:0003009)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 1.9 GO:0042825 TAP complex(GO:0042825)
0.2 3.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 1.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 0.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 7.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.7 GO:0072557 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
0.1 0.5 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 1.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 2.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 0.4 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 3.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 4.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.6 GO:0031672 A band(GO:0031672)
0.0 1.9 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 5.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.4 GO:0030492 hemoglobin binding(GO:0030492)
0.8 2.5 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.8 2.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.3 1.6 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 2.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 0.7 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 1.0 GO:0055100 adiponectin binding(GO:0055100)
0.2 1.9 GO:0046979 MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.2 2.2 GO:0019863 IgE binding(GO:0019863)
0.2 0.7 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 1.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.6 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.5 GO:0004583 alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.3 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 1.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 7.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.4 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.2 GO:0019166 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 2.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.9 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 2.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0032396 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.1 1.0 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 2.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 7.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 7.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin