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Illumina Body Map 2 (GSE30611)

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Results for TBX4

Z-value: 0.89

Motif logo

Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
ENSG00000121075.11 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg38_v1_chr17_+_61452378_61452437-0.281.2e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_115180037 2.39 ENST00000514154.1
ENST00000282369.7
tripartite motif containing 36
chr12_+_18738102 1.93 ENST00000317658.5
capping actin protein of muscle Z-line subunit alpha 3
chr8_+_102551583 1.86 ENST00000285402.4
outer dense fiber of sperm tails 1
chr10_+_44911316 1.85 ENST00000544540.5
ENST00000389583.5
transmembrane protein 72
chr6_-_130215629 1.69 ENST00000532763.5
sterile alpha motif domain containing 3
chr21_+_29130961 1.47 ENST00000399925.5
MAP3K7 C-terminal like
chr1_+_154405326 1.43 ENST00000368485.8
interleukin 6 receptor
chr1_-_11847772 1.43 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr12_-_18738006 1.42 ENST00000266505.12
ENST00000543242.5
ENST00000539072.5
ENST00000541966.5
ENST00000648272.1
phospholipase C zeta 1
chr7_+_143316105 1.37 ENST00000343257.7
ENST00000650516.1
chloride voltage-gated channel 1
chr1_+_154405193 1.33 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr3_+_167735238 1.31 ENST00000472941.5
serpin family I member 1
chr5_+_139795795 1.30 ENST00000274710.4
pleckstrin and Sec7 domain containing 2
chr1_+_26410809 1.30 ENST00000254231.4
ENST00000326279.11
lin-28 homolog A
chr21_+_29130630 1.29 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr1_-_24930263 1.26 ENST00000308873.11
RUNX family transcription factor 3
chr7_+_142666272 1.21 ENST00000604952.1
MT-RNR2 like 6
chr1_+_154405573 1.17 ENST00000512471.1
interleukin 6 receptor
chr3_+_167735704 1.16 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr9_-_97938157 1.07 ENST00000616898.2
hemogen
chr11_-_128867268 1.07 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr11_-_128867364 1.07 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr12_-_90955172 1.07 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr1_+_15736251 1.04 ENST00000294454.6
solute carrier family 25 member 34
chr15_-_38560050 1.03 ENST00000558432.5
RAS guanyl releasing protein 1
chr18_-_58629084 0.99 ENST00000361673.4
alpha kinase 2
chrX_+_70423031 0.98 ENST00000453994.6
ENST00000538649.5
ENST00000536730.5
glycerophosphodiester phosphodiesterase domain containing 2
chr11_+_122838492 0.98 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr8_+_55102012 0.94 ENST00000327381.7
XK related 4
chr5_+_55024250 0.91 ENST00000231009.3
granzyme K
chrX_+_71223216 0.89 ENST00000361726.7
gap junction protein beta 1
chr11_-_16356538 0.88 ENST00000683767.1
SRY-box transcription factor 6
chr7_-_28180735 0.88 ENST00000283928.10
JAZF zinc finger 1
chrX_+_124346544 0.84 ENST00000371139.9
SH2 domain containing 1A
chr5_-_75511213 0.83 ENST00000644445.1
ENST00000646302.1
ENST00000644912.1
ENST00000642809.1
ENST00000644377.1
ceramide transporter 1
chr1_-_11848345 0.83 ENST00000376476.1
natriuretic peptide A
chr11_-_85719313 0.82 ENST00000526999.5
synaptotagmin like 2
chr22_+_40045451 0.82 ENST00000402203.5
trinucleotide repeat containing adaptor 6B
chr7_+_69967464 0.81 ENST00000664521.1
activator of transcription and developmental regulator AUTS2
chr15_+_92393841 0.80 ENST00000268164.8
ENST00000539113.5
ENST00000555434.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr2_+_218607914 0.80 ENST00000417849.5
phospholipase C delta 4
chr3_+_134795248 0.78 ENST00000398015.8
EPH receptor B1
chrX_+_70423301 0.77 ENST00000374382.4
glycerophosphodiester phosphodiesterase domain containing 2
chr10_-_16521871 0.74 ENST00000298943.4
complement C1q like 3
chrX_+_124346525 0.73 ENST00000360027.4
SH2 domain containing 1A
chr10_-_75109085 0.71 ENST00000607131.5
dual specificity phosphatase 13
chr2_+_102473219 0.70 ENST00000295269.5
solute carrier family 9 member A4
chr3_+_134795277 0.69 ENST00000647596.1
EPH receptor B1
chr1_+_172659095 0.69 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr2_+_209771972 0.69 ENST00000439458.5
ENST00000272845.10
unc-80 homolog, NALCN channel complex subunit
chr2_+_209771814 0.66 ENST00000673951.1
ENST00000673920.1
unc-80 homolog, NALCN channel complex subunit
chr2_+_218607861 0.66 ENST00000450993.7
phospholipase C delta 4
chr10_-_101229449 0.66 ENST00000370193.4
ladybird homeobox 1
chr8_-_94895195 0.66 ENST00000308108.9
ENST00000396133.7
cyclin E2
chr20_+_46029165 0.66 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
solute carrier family 12 member 5
chr8_+_737595 0.65 ENST00000637795.2
DLG associated protein 2
chr8_+_55102448 0.65 ENST00000622811.1
XK related 4
chr5_-_75511596 0.64 ENST00000643158.1
ENST00000261415.12
ENST00000646713.1
ENST00000643773.1
ENST00000645866.1
ENST00000644072.2
ENST00000643780.2
ENST00000645483.1
ENST00000642556.1
ENST00000646511.1
ceramide transporter 1
chr6_+_104940866 0.63 ENST00000637759.1
lin-28 homolog B
chr1_-_225889143 0.62 ENST00000272134.5
left-right determination factor 1
chr1_-_37034492 0.62 ENST00000373091.8
glutamate ionotropic receptor kainate type subunit 3
chr15_+_36702009 0.60 ENST00000562489.1
CDAN1 interacting nuclease 1
chr12_-_89630552 0.60 ENST00000393164.6
ATPase plasma membrane Ca2+ transporting 1
chr1_-_110606009 0.60 ENST00000640774.2
ENST00000638616.2
potassium voltage-gated channel subfamily A member 2
chr12_+_57460127 0.59 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr10_-_97185507 0.59 ENST00000314867.9
slit guidance ligand 1
chrX_+_124346571 0.58 ENST00000477673.2
SH2 domain containing 1A
chr2_-_27264083 0.58 ENST00000432351.5
solute carrier family 30 member 3
chr14_-_20590823 0.57 ENST00000556526.1
ribonuclease A family member 12 (inactive)
chr2_-_2326378 0.57 ENST00000647618.1
myelin transcription factor 1 like
chr17_-_63873676 0.56 ENST00000613718.3
ENST00000392886.7
ENST00000345366.8
ENST00000336844.9
ENST00000560142.5
chorionic somatomammotropin hormone 2
chr11_-_62921807 0.55 ENST00000543973.1
cholinergic receptor muscarinic 1
chr1_+_206507520 0.54 ENST00000579436.7
Ras association domain family member 5
chr4_+_87650277 0.54 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr8_+_94895763 0.53 ENST00000523378.5
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr2_+_176107272 0.53 ENST00000249504.7
homeobox D11
chr5_+_150660841 0.52 ENST00000297130.4
myozenin 3
chr15_+_75724034 0.51 ENST00000332145.3
outer dense fiber of sperm tails 3 like 1
chr5_+_83471668 0.51 ENST00000342785.8
ENST00000343200.9
versican
chr2_-_199457931 0.50 ENST00000417098.6
SATB homeobox 2
chr5_-_79514127 0.49 ENST00000334082.11
homer scaffold protein 1
chr12_-_110742929 0.49 ENST00000340766.9
protein phosphatase 1 catalytic subunit gamma
chr5_+_150661243 0.49 ENST00000517768.6
myozenin 3
chr16_+_2537997 0.48 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr1_+_69567906 0.48 ENST00000651989.2
leucine rich repeat containing 7
chr11_+_64306227 0.47 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr3_-_187745460 0.47 ENST00000406870.7
BCL6 transcription repressor
chr8_+_22578249 0.47 ENST00000456545.5
PDZ and LIM domain 2
chr1_-_37034129 0.46 ENST00000373093.4
glutamate ionotropic receptor kainate type subunit 3
chr8_+_32647080 0.46 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr2_-_40453438 0.46 ENST00000455476.5
solute carrier family 8 member A1
chr16_-_18926408 0.45 ENST00000446231.7
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chrX_-_138711663 0.45 ENST00000315930.11
fibroblast growth factor 13
chr17_-_39401593 0.45 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
F-box and leucine rich repeat protein 20
chr11_-_27722021 0.45 ENST00000314915.6
brain derived neurotrophic factor
chr19_+_35031263 0.45 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr20_+_46029206 0.43 ENST00000243964.7
solute carrier family 12 member 5
chr1_+_206507546 0.43 ENST00000580449.5
ENST00000581503.6
Ras association domain family member 5
chr3_-_66500973 0.43 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr14_+_52730154 0.43 ENST00000354586.5
ENST00000442123.6
serine/threonine/tyrosine interacting protein
chr1_+_151612001 0.42 ENST00000642376.1
ENST00000368843.8
ENST00000458013.7
sorting nexin 27
chr15_+_60004305 0.42 ENST00000396057.6
forkhead box B1
chr14_+_93430927 0.42 ENST00000393151.6
unc-79 homolog, NALCN channel complex subunit
chr6_-_31652115 0.42 ENST00000454165.1
ENST00000428326.5
ENST00000452994.5
BAG cochaperone 6
chr12_-_116276759 0.42 ENST00000548743.2
mediator complex subunit 13L
chr3_+_63819293 0.41 ENST00000295896.13
chromosome 3 open reading frame 49
chr4_+_139301478 0.41 ENST00000296543.10
ENST00000398947.1
N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr17_-_63896568 0.40 ENST00000610991.1
ENST00000316193.13
ENST00000329882.8
chorionic somatomammotropin hormone 1
chr14_+_93430853 0.40 ENST00000553484.5
unc-79 homolog, NALCN channel complex subunit
chr8_+_32548210 0.40 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr6_-_31651920 0.39 ENST00000434444.5
BAG cochaperone 6
chr8_+_32548303 0.39 ENST00000650967.1
neuregulin 1
chr2_-_110534010 0.39 ENST00000437167.1
RANBP2 like and GRIP domain containing 6
chr15_-_82647123 0.39 ENST00000569257.5
cytoplasmic polyadenylation element binding protein 1
chr11_+_111878926 0.39 ENST00000528125.5
chromosome 11 open reading frame 1
chr11_-_85719111 0.39 ENST00000529581.5
ENST00000533577.1
synaptotagmin like 2
chr14_+_90398159 0.39 ENST00000544280.6
calmodulin 1
chr11_-_85719045 0.38 ENST00000533057.6
ENST00000533892.5
synaptotagmin like 2
chr14_+_78170336 0.38 ENST00000634499.2
ENST00000335750.7
neurexin 3
chrX_-_19670983 0.38 ENST00000379716.5
SH3 domain containing kinase binding protein 1
chr15_+_90906741 0.38 ENST00000557865.5
mannosidase alpha class 2A member 2
chr2_+_37231761 0.37 ENST00000416653.5
NADH:ubiquinone oxidoreductase complex assembly factor 7
chr2_+_37231798 0.37 ENST00000439218.5
ENST00000432075.1
NADH:ubiquinone oxidoreductase complex assembly factor 7
chr3_-_52409783 0.37 ENST00000470173.1
ENST00000296288.9
ENST00000460680.6
BRCA1 associated protein 1
chr12_+_21372899 0.37 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr16_+_2537979 0.36 ENST00000566659.1
3-phosphoinositide dependent protein kinase 1
chr12_-_120368069 0.36 ENST00000546985.1
musashi RNA binding protein 1
chr14_+_75279961 0.36 ENST00000557139.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr5_-_34043205 0.36 ENST00000382065.8
ENST00000231338.7
C1q and TNF related 3
chr4_-_139301204 0.36 ENST00000505036.5
ENST00000539002.5
ENST00000544855.5
NADH:ubiquinone oxidoreductase subunit C1
chr2_+_60881515 0.35 ENST00000295025.12
REL proto-oncogene, NF-kB subunit
chrX_-_139205006 0.35 ENST00000436198.5
ENST00000626909.2
fibroblast growth factor 13
chr1_+_158355894 0.35 ENST00000368162.2
CD1e molecule
chr14_+_78403686 0.35 ENST00000553631.1
ENST00000554719.5
neurexin 3
chr5_+_75512058 0.34 ENST00000514296.5
DNA polymerase kappa
chrM_+_10464 0.34 ENST00000361335.1
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L
chr7_-_150978284 0.34 ENST00000262186.10
potassium voltage-gated channel subfamily H member 2
chr2_+_17816458 0.33 ENST00000281047.4
mesogenin 1
chr12_-_110742839 0.33 ENST00000551676.5
ENST00000550991.5
ENST00000335007.10
protein phosphatase 1 catalytic subunit gamma
chr22_-_41946729 0.32 ENST00000402420.1
centromere protein M
chr17_-_7329266 0.32 ENST00000571887.5
ENST00000315614.11
ENST00000399464.7
ENST00000570460.5
neuralized E3 ubiquitin protein ligase 4
chr7_-_72336995 0.32 ENST00000329008.9
calneuron 1
chr9_-_72364504 0.32 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chr6_+_49499916 0.31 ENST00000371197.9
glycine-N-acyltransferase like 3
chr2_-_61471062 0.31 ENST00000398571.7
ubiquitin specific peptidase 34
chr1_+_145927105 0.31 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr11_-_33869816 0.30 ENST00000395833.7
LIM domain only 2
chrX_+_110002635 0.30 ENST00000372072.7
transmembrane protein 164
chr11_+_73647645 0.30 ENST00000545798.5
ENST00000539157.5
ENST00000546251.5
ENST00000535582.5
ENST00000538227.5
pleckstrin homology domain containing B1
chr11_-_33892010 0.30 ENST00000257818.3
LIM domain only 2
chr11_+_61680373 0.30 ENST00000257215.10
diacylglycerol lipase alpha
chr17_-_63918817 0.29 ENST00000458650.6
ENST00000351388.8
ENST00000342364.8
ENST00000617086.1
ENST00000323322.10
ENST00000392824.8
growth hormone 1
chorionic somatomammotropin hormone like 1
chr11_-_132943732 0.29 ENST00000374778.4
opioid binding protein/cell adhesion molecule like
chr11_+_17547259 0.29 ENST00000399397.6
ENST00000399391.7
otogelin
chr6_-_31651964 0.29 ENST00000433828.5
ENST00000456286.5
BAG cochaperone 6
chr12_+_113185702 0.29 ENST00000548278.2
RBPJ interacting and tubulin associated 1
chr2_-_25252251 0.29 ENST00000380746.8
ENST00000402667.1
DNA methyltransferase 3 alpha
chr8_+_122781621 0.29 ENST00000314393.6
zinc fingers and homeoboxes 2
chr11_-_85719160 0.29 ENST00000389958.7
ENST00000527794.5
synaptotagmin like 2
chr4_-_113517607 0.29 ENST00000509594.1
calcium/calmodulin dependent protein kinase II delta
chrM_+_10759 0.29 ENST00000361381.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4
chr7_+_27242796 0.28 ENST00000496902.7
even-skipped homeobox 1
chr3_+_107645836 0.28 ENST00000413213.5
BBX high mobility group box domain containing
chr2_+_60881553 0.28 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chr3_+_107645922 0.28 ENST00000449271.5
ENST00000425868.5
ENST00000449213.5
BBX high mobility group box domain containing
chr11_-_114400417 0.27 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr15_-_82647503 0.27 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr11_+_94021346 0.27 ENST00000315765.10
hephaestin like 1
chrM_+_10055 0.27 ENST00000361227.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
chr4_-_101347471 0.27 ENST00000323055.10
ENST00000512215.5
protein phosphatase 3 catalytic subunit alpha
chrX_+_47191399 0.27 ENST00000412206.5
ENST00000427561.5
ubiquitin like modifier activating enzyme 1
chr4_-_44448796 0.27 ENST00000360029.4
potassium channel tetramerization domain containing 8
chr10_+_7818497 0.26 ENST00000344293.6
TATA-box binding protein associated factor 3
chr1_-_182672232 0.26 ENST00000508450.5
regulator of G protein signaling 8
chr15_-_82806054 0.26 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
fibronectin type III and SPRY domain containing 2
chr5_+_140107777 0.25 ENST00000505703.2
ENST00000651386.1
purine rich element binding protein A
chr10_+_93073873 0.25 ENST00000224356.5
cytochrome P450 family 26 subfamily A member 1
chr3_+_63819368 0.25 ENST00000616659.1
chromosome 3 open reading frame 49
chr4_-_23881282 0.25 ENST00000613098.4
PPARG coactivator 1 alpha
chr11_-_74949079 0.24 ENST00000528219.5
ENST00000684022.1
ENST00000531852.5
X-ray radiation resistance associated 1
chr11_-_18322178 0.24 ENST00000531848.1
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
chr11_-_74949114 0.23 ENST00000527087.5
X-ray radiation resistance associated 1
chr10_+_113125536 0.23 ENST00000349937.7
transcription factor 7 like 2
chr15_-_89751292 0.22 ENST00000300057.4
mesoderm posterior bHLH transcription factor 1
chr11_-_74949020 0.22 ENST00000525407.5
X-ray radiation resistance associated 1
chr11_+_73647701 0.21 ENST00000543524.5
pleckstrin homology domain containing B1
chr7_-_72337601 0.21 ENST00000446128.1
calneuron 1
chr9_-_114930508 0.21 ENST00000223795.3
ENST00000618336.4
TNF superfamily member 8
chr7_+_27242700 0.20 ENST00000222761.7
even-skipped homeobox 1
chr12_-_119803383 0.20 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr2_-_25252072 0.19 ENST00000683760.1
DNA methyltransferase 3 alpha
chr2_+_37231633 0.19 ENST00000002125.9
ENST00000336237.10
ENST00000431821.5
NADH:ubiquinone oxidoreductase complex assembly factor 7
chr11_-_18322122 0.19 ENST00000349215.8
ENST00000396253.7
ENST00000438420.6
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
chr20_+_46029009 0.19 ENST00000608944.5
solute carrier family 12 member 5
chr4_-_101347492 0.19 ENST00000394854.8
protein phosphatase 3 catalytic subunit alpha
chrX_+_123962040 0.18 ENST00000435215.5
stromal antigen 2
chr4_-_185811088 0.18 ENST00000421639.5
sorbin and SH3 domain containing 2
chr11_-_111879154 0.17 ENST00000260257.9
ferredoxin-fold anticodon binding domain containing 1
chr16_+_57106021 0.16 ENST00000566259.1
copine 2
chr17_-_45425620 0.16 ENST00000376922.6
Rho GTPase activating protein 27

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.9 GO:0002384 hepatic immune response(GO:0002384)
0.5 1.5 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.4 2.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.3 1.3 GO:0040040 thermosensory behavior(GO:0040040)
0.3 1.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 1.4 GO:0007343 egg activation(GO:0007343)
0.2 0.6 GO:0060032 notochord regression(GO:0060032)
0.2 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.4 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.1 1.0 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.9 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 1.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.9 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.3 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.1 GO:1904327 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.5 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.5 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.6 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 1.4 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.2 GO:2000184 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033) glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) response to resveratrol(GO:1904638) cellular response to resveratrol(GO:1904639) positive regulation of progesterone biosynthetic process(GO:2000184)
0.1 2.6 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.3 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.2 GO:0008078 mesodermal cell migration(GO:0008078) cardiac cell fate determination(GO:0060913) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.4 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.6 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 1.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.3 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.8 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 3.4 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.5 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.8 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.7 GO:0048664 neuron fate determination(GO:0048664)
0.0 1.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.2 GO:0097369 sodium ion import(GO:0097369)
0.0 0.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.8 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.9 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.8 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.4 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 2.1 GO:0010107 potassium ion import(GO:0010107)
0.0 1.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 2.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789) cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 2.5 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.4 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.6 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.2 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.7 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 1.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.2 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.1 3.3 GO:0042629 mast cell granule(GO:0042629)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.7 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 4.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 1.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 0.6 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.2 2.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.0 GO:0051373 FATZ binding(GO:0051373)
0.1 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 1.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.4 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 1.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 3.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.8 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.4 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.1 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID FOXO PATHWAY FoxO family signaling
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 2.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events