Illumina Body Map 2 (GSE30611)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
ASCL2 | hg38_v1_chr11_-_2270584_2270595 | 0.20 | 2.8e-01 | Click! |
TCF12 | hg38_v1_chr15_+_56919120_56919165 | -0.12 | 5.0e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 135.7 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.4 | 76.0 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.3 | 23.4 | GO:0006968 | cellular defense response(GO:0006968) |
0.1 | 16.2 | GO:0002250 | adaptive immune response(GO:0002250) |
0.2 | 10.8 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
0.0 | 10.5 | GO:0042119 | neutrophil activation(GO:0042119) |
0.8 | 9.4 | GO:0072564 | blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
0.4 | 9.2 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
0.0 | 8.5 | GO:0031398 | positive regulation of protein ubiquitination(GO:0031398) |
0.2 | 8.0 | GO:0050779 | RNA destabilization(GO:0050779) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 54.1 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 45.9 | GO:0005615 | extracellular space(GO:0005615) |
0.2 | 26.5 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
0.1 | 23.8 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
0.1 | 18.4 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 17.0 | GO:0016605 | PML body(GO:0016605) |
0.1 | 16.0 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.1 | 11.8 | GO:0005811 | lipid particle(GO:0005811) |
0.1 | 8.7 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 8.2 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 159.7 | GO:0003823 | antigen binding(GO:0003823) |
0.9 | 65.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 19.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.1 | 16.6 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.1 | 13.0 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.1 | 12.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 11.2 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.2 | 11.0 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.2 | 10.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.6 | 10.4 | GO:0042608 | T cell receptor binding(GO:0042608) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 45.8 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
0.3 | 24.1 | PID BCR 5PATHWAY | BCR signaling pathway |
0.3 | 22.4 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
0.3 | 19.0 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.2 | 17.0 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
0.1 | 12.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.3 | 11.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.2 | 10.0 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
0.2 | 8.5 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
0.3 | 7.6 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 21.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.3 | 20.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.1 | 17.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 16.9 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
0.2 | 16.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.2 | 16.2 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.4 | 15.5 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.1 | 11.6 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
0.3 | 10.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.4 | 9.0 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |