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Illumina Body Map 2 (GSE30611)

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Results for TCF21

Z-value: 1.08

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
ENSG00000118526.7 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg38_v1_chr6_+_133889105_1338891200.038.6e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_45322867 5.76 ENST00000221476.4
creatine kinase, M-type
chr11_+_1922779 4.29 ENST00000641119.1
ENST00000641225.1
ENST00000641787.1
ENST00000397301.5
ENST00000397304.6
ENST00000446240.1
troponin T3, fast skeletal type
chr8_+_85438850 3.29 ENST00000285381.3
carbonic anhydrase 3
chr7_+_80646436 3.16 ENST00000419819.2
CD36 molecule
chr16_-_31428325 3.14 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr7_+_80646347 3.09 ENST00000413265.5
CD36 molecule
chr1_+_171185293 3.08 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr17_+_47209035 2.42 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr15_+_57599411 2.17 ENST00000569089.1
myocardial zonula adherens protein
chr15_+_63048576 2.17 ENST00000559281.6
tropomyosin 1
chr2_-_218010202 2.12 ENST00000646520.1
tensin 1
chr19_+_11541125 2.10 ENST00000587087.5
calponin 1
chr12_-_10723307 1.96 ENST00000279550.11
ENST00000228251.9
Y-box binding protein 3
chr3_+_8733779 1.87 ENST00000343849.3
ENST00000397368.2
caveolin 3
chr10_-_7619660 1.83 ENST00000613909.4
inter-alpha-trypsin inhibitor heavy chain 5
chr3_+_148865288 1.82 ENST00000296046.4
carboxypeptidase A3
chr16_+_55488580 1.77 ENST00000570283.1
matrix metallopeptidase 2
chr3_-_9878765 1.75 ENST00000430427.6
ENST00000383817.5
ENST00000679265.1
cell death inducing DFFA like effector c
chr17_+_42851167 1.72 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chr1_-_162023632 1.67 ENST00000367940.2
olfactomedin like 2B
chr9_+_97853217 1.66 ENST00000375123.5
forkhead box E1
chr12_+_12891554 1.65 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chrX_+_151716023 1.55 ENST00000370350.7
fetal and adult testis expressed 1
chr1_+_167094049 1.54 ENST00000361200.7
serine/threonine/tyrosine interacting like 2
chr4_+_168711416 1.53 ENST00000649826.1
palladin, cytoskeletal associated protein
chr14_-_106374129 1.50 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr4_+_168712159 1.45 ENST00000510998.5
palladin, cytoskeletal associated protein
chr12_-_52519117 1.45 ENST00000551188.5
keratin 5
chr9_-_101594918 1.44 ENST00000374806.2
protein phosphatase 3 regulatory subunit B, beta
chr10_-_95441015 1.42 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr16_+_30372291 1.39 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_-_101594995 1.37 ENST00000636434.1
protein phosphatase 3 regulatory subunit B, beta
chrX_-_79367307 1.32 ENST00000373298.7
integral membrane protein 2A
chr12_-_104050112 1.30 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
glycosyltransferase 8 domain containing 2
chr6_+_116511626 1.29 ENST00000368599.4
calcium homeostasis modulator family member 5
chr10_-_29634964 1.28 ENST00000375398.6
ENST00000355867.8
supervillin
chr15_+_63048535 1.26 ENST00000560959.5
tropomyosin 1
chr15_+_63048658 1.26 ENST00000560615.5
ENST00000651577.1
tropomyosin 1
chr8_+_141413316 1.25 ENST00000329397.6
protein tyrosine phosphatase 4A3
chr8_+_133017693 1.24 ENST00000518108.1
thyroglobulin
chr1_-_160711803 1.24 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48 molecule
chr3_+_32391871 1.22 ENST00000465248.1
CKLF like MARVEL transmembrane domain containing 7
chr3_+_32391694 1.21 ENST00000349718.8
CKLF like MARVEL transmembrane domain containing 7
chr2_-_127643212 1.19 ENST00000409286.5
LIM zinc finger domain containing 2
chr21_+_10521569 1.18 ENST00000612957.4
ENST00000427445.6
ENST00000612746.1
ENST00000618007.5
transmembrane phosphatase with tensin homology
chr15_+_63048436 1.17 ENST00000334895.10
ENST00000404484.9
ENST00000558910.3
ENST00000317516.12
tropomyosin 1
chr7_+_150716603 1.16 ENST00000307194.6
ENST00000611999.4
GTPase, IMAP family member 1
GIMAP1-GIMAP5 readthrough
chr7_-_48029102 1.16 ENST00000297325.9
ENST00000412142.5
ENST00000395572.6
Sad1 and UNC84 domain containing 3
chr1_+_212565334 1.13 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr8_+_66043413 1.12 ENST00000522619.1
DnaJ heat shock protein family (Hsp40) member C5 beta
chr19_-_49325181 1.10 ENST00000454748.7
ENST00000335875.9
ENST00000598828.1
solute carrier family 6 member 16
chr1_+_99646025 1.09 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr11_+_1870871 1.09 ENST00000417766.5
lymphocyte specific protein 1
chr5_-_170389349 1.09 ENST00000274629.9
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr9_+_110090197 1.09 ENST00000480388.1
PALM2 and AKAP2 fusion
chr17_+_47209338 1.08 ENST00000393450.5
myosin light chain 4
chr3_+_32391841 1.08 ENST00000334983.10
CKLF like MARVEL transmembrane domain containing 7
chr1_+_22636577 1.08 ENST00000374642.8
ENST00000438241.1
complement C1q A chain
chr22_+_22922594 1.06 ENST00000390331.3
immunoglobulin lambda constant 7
chrX_+_151716068 1.04 ENST00000417321.1
fetal and adult testis expressed 1
chr1_-_205422050 1.03 ENST00000367153.9
LEM domain containing 1
chr1_+_172452885 1.03 ENST00000367725.4
chromosome 1 open reading frame 105
chr9_+_68356603 1.03 ENST00000396396.6
phosphoglucomutase 5
chr6_-_31729260 1.02 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr8_-_41665261 1.02 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ankyrin 1
chr2_+_37950432 1.01 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chr3_-_52834901 1.00 ENST00000486659.5
musculoskeletal, embryonic nuclear protein 1
chr6_-_31728877 1.00 ENST00000437288.5
dimethylarginine dimethylaminohydrolase 2
chr7_+_134565098 1.00 ENST00000652743.1
aldo-keto reductase family 1 member B15
chr3_-_52835011 0.99 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr17_+_79034185 0.99 ENST00000581774.5
C1q and TNF related 1
chr18_+_3247778 0.99 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
myosin light chain 12A
chr6_-_31729478 0.96 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr1_+_153628393 0.94 ENST00000368696.3
ENST00000292169.6
ENST00000436839.1
S100 calcium binding protein A1
chr6_-_30690968 0.93 ENST00000376420.9
ENST00000376421.7
nurim
chr18_+_6834473 0.90 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
Rho GTPase activating protein 28
chr19_+_46298382 0.89 ENST00000244303.10
ENST00000533145.5
ENST00000472815.5
hypoxia inducible factor 3 subunit alpha
chr10_+_92689946 0.89 ENST00000282728.10
hematopoietically expressed homeobox
chr2_+_37950476 0.87 ENST00000402091.3
regulator of microtubule dynamics 2
chr17_-_7290392 0.87 ENST00000571464.1
Y-box binding protein 2
chr11_-_1486763 0.84 ENST00000329957.7
MOB kinase activator 2
chr13_-_77919459 0.83 ENST00000643890.1
endothelin receptor type B
chr12_-_50283472 0.83 ENST00000551691.5
ENST00000394943.7
ENST00000341247.8
LIM domain and actin binding 1
chr2_+_219434825 0.83 ENST00000312358.12
striated muscle enriched protein kinase
chr3_-_105869035 0.82 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr17_-_3513768 0.82 ENST00000570318.1
ENST00000541913.5
spermatogenesis associated 22
chr6_+_28259285 0.82 ENST00000343684.4
NFKB activating protein like
chr2_-_88979016 0.82 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr22_+_37675629 0.81 ENST00000215909.10
galectin 1
chr11_+_47248924 0.81 ENST00000481889.6
ENST00000436778.5
ENST00000531660.5
ENST00000407404.5
nuclear receptor subfamily 1 group H member 3
chr5_+_136028979 0.81 ENST00000442011.7
transforming growth factor beta induced
chr10_+_121989187 0.81 ENST00000513429.5
ENST00000515273.5
ENST00000515603.5
transforming acidic coiled-coil containing protein 2
chr21_+_10521536 0.80 ENST00000622113.4
transmembrane phosphatase with tensin homology
chr10_+_121989138 0.80 ENST00000369005.6
transforming acidic coiled-coil containing protein 2
chr3_-_177197210 0.79 ENST00000431421.5
ENST00000422066.5
ENST00000413084.5
ENST00000673974.1
ENST00000422442.6
TBL1X receptor 1
chr2_+_46479565 0.79 ENST00000434431.2
transmembrane protein 247
chr2_-_157439403 0.79 ENST00000418920.5
cytohesin 1 interacting protein
chr3_-_105868964 0.79 ENST00000394030.8
Cbl proto-oncogene B
chr8_+_143213192 0.79 ENST00000622500.2
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr6_-_31729785 0.79 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr7_+_150737382 0.78 ENST00000358647.5
GTPase, IMAP family member 5
chr5_-_170389634 0.78 ENST00000521859.1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr5_-_151093566 0.76 ENST00000521001.1
TNFAIP3 interacting protein 1
chr6_+_54083423 0.75 ENST00000460844.6
ENST00000370876.6
muscular LMNA interacting protein
chr5_-_180802790 0.74 ENST00000504671.1
ENST00000507384.1
ENST00000307826.5
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chrX_-_107717054 0.74 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr4_+_122923067 0.73 ENST00000675612.1
ENST00000274008.5
spermatogenesis associated 5
chr2_+_87338511 0.73 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr19_-_12778412 0.72 ENST00000589400.5
ENST00000590839.5
ENST00000592079.5
hook microtubule tethering protein 2
chr22_-_21952827 0.72 ENST00000397495.8
ENST00000263212.10
protein phosphatase, Mg2+/Mn2+ dependent 1F
chr16_+_85902689 0.72 ENST00000563180.1
ENST00000564617.5
ENST00000564803.5
interferon regulatory factor 8
chr2_+_218672291 0.72 ENST00000440309.5
ENST00000424080.1
serine/threonine kinase 36
chr22_+_44031345 0.72 ENST00000444029.5
parvin beta
chr7_-_122702912 0.72 ENST00000447240.1
ENST00000434824.2
ring finger protein 148
chr8_-_41665200 0.71 ENST00000335651.6
ankyrin 1
chr3_-_177197248 0.71 ENST00000427349.5
ENST00000352800.10
TBL1X receptor 1
chr8_+_25459190 0.71 ENST00000380665.3
ENST00000330560.8
cell division cycle associated 2
chr22_-_23580223 0.70 ENST00000249053.3
ENST00000330377.3
ENST00000438703.1
immunoglobulin lambda like polypeptide 1
chr2_+_230416239 0.70 ENST00000409824.5
ENST00000409341.5
ENST00000409112.5
SP100 nuclear antigen
chr20_+_31739260 0.70 ENST00000340513.4
ENST00000300403.11
TPX2 microtubule nucleation factor
chr11_+_47248885 0.69 ENST00000395397.7
ENST00000405576.5
nuclear receptor subfamily 1 group H member 3
chr7_+_121076570 0.69 ENST00000443817.1
cadherin like and PC-esterase domain containing 1
chr19_-_39833615 0.69 ENST00000593685.5
ENST00000600611.5
dual specificity tyrosine phosphorylation regulated kinase 1B
chr17_+_4583998 0.69 ENST00000338859.8
smoothelin like 2
chr1_+_145927105 0.68 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr6_-_11382247 0.68 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr2_+_56183973 0.68 ENST00000407595.3
coiled-coil domain containing 85A
chr9_+_27109135 0.68 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase
chr2_+_102104563 0.68 ENST00000409589.5
ENST00000409329.5
interleukin 1 receptor type 1
chr14_-_106811131 0.67 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr4_-_46909235 0.67 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr2_+_230416156 0.67 ENST00000427101.6
SP100 nuclear antigen
chr3_-_177197429 0.67 ENST00000457928.7
TBL1X receptor 1
chr1_-_23531206 0.66 ENST00000361729.3
E2F transcription factor 2
chr6_+_18387326 0.66 ENST00000259939.4
ring finger protein 144B
chr15_+_43792839 0.65 ENST00000409614.1
small EDRK-rich factor 2
chr13_-_77919390 0.65 ENST00000475537.2
ENST00000646605.1
endothelin receptor type B
chr11_-_74949079 0.64 ENST00000528219.5
ENST00000684022.1
ENST00000531852.5
X-ray radiation resistance associated 1
chr11_+_827545 0.64 ENST00000528542.6
calcium release activated channel regulator 2B
chr11_-_74949114 0.63 ENST00000527087.5
X-ray radiation resistance associated 1
chr1_+_186296267 0.63 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
proteoglycan 4
chr8_-_94949350 0.63 ENST00000448464.6
ENST00000342697.5
tumor protein p53 inducible nuclear protein 1
chr2_+_218672027 0.62 ENST00000392105.7
ENST00000455724.5
ENST00000295709.8
serine/threonine kinase 36
chr11_-_74949020 0.62 ENST00000525407.5
X-ray radiation resistance associated 1
chr12_+_16347637 0.62 ENST00000543076.5
ENST00000396210.8
microsomal glutathione S-transferase 1
chr2_+_90234809 0.62 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr11_+_33258304 0.61 ENST00000531504.5
ENST00000456517.2
homeodomain interacting protein kinase 3
chr20_+_38581186 0.61 ENST00000373348.4
ENST00000537425.2
ENST00000416116.2
adipogenin
chr7_-_76627240 0.61 ENST00000275569.8
ENST00000310842.9
POM121 and ZP3 fusion
chr9_-_127778659 0.61 ENST00000314830.13
SH2 domain containing 3C
chr19_-_33225844 0.61 ENST00000253188.8
solute carrier family 7 member 10
chr2_-_233854566 0.61 ENST00000432087.5
ENST00000441687.5
ENST00000414924.5
Holliday junction recognition protein
chr12_+_8697875 0.61 ENST00000357529.7
ribosomal modification protein rimK like family member B
chr1_+_24556087 0.60 ENST00000374392.3
non-compact myelin associated protein
chr12_+_8697945 0.60 ENST00000535829.6
ribosomal modification protein rimK like family member B
chr2_+_230416190 0.60 ENST00000340126.9
ENST00000432979.5
SP100 nuclear antigen
chr11_-_88175432 0.60 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38, member RAS oncogene family
chr13_-_103066411 0.59 ENST00000245312.5
solute carrier family 10 member 2
chr15_+_89243945 0.59 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FA complementation group I
chr13_-_41061373 0.59 ENST00000405737.2
E74 like ETS transcription factor 1
chr11_+_827913 0.59 ENST00000525077.2
calcium release activated channel regulator 2B
chr17_-_7394800 0.59 ENST00000574401.5
phospholipid scramblase 3
chrX_-_11427725 0.59 ENST00000380736.5
Rho GTPase activating protein 6
chr4_-_46909206 0.58 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr1_+_27935022 0.58 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr15_-_42457513 0.58 ENST00000565611.5
ENST00000263805.8
zinc finger protein 106
chr11_-_16397521 0.58 ENST00000533411.5
SRY-box transcription factor 6
chr20_-_3682218 0.58 ENST00000379861.8
ADAM metallopeptidase domain 33
chr13_-_77918788 0.57 ENST00000626030.1
endothelin receptor type B
chr1_-_201469151 0.57 ENST00000367311.5
ENST00000367309.1
pleckstrin homology like domain family A member 3
chr17_-_7394514 0.57 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
phospholipid scramblase 3
chrX_+_48574477 0.56 ENST00000376759.8
RNA binding motif protein 3
chr17_-_15262537 0.56 ENST00000395936.7
ENST00000675819.1
ENST00000674707.1
ENST00000675854.1
ENST00000426385.4
ENST00000395938.7
ENST00000612492.5
ENST00000675808.1
peripheral myelin protein 22
chr15_-_78811415 0.56 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr8_-_19682576 0.56 ENST00000332246.10
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr22_+_38656627 0.56 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr17_-_41102209 0.56 ENST00000440582.1
keratin associated protein 4-16
chr11_+_59142811 0.55 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr8_-_9150648 0.55 ENST00000310455.4
protein phosphatase 1 regulatory subunit 3B
chr3_-_169146527 0.55 ENST00000475754.5
ENST00000484519.5
MDS1 and EVI1 complex locus
chr15_-_42457556 0.55 ENST00000565948.1
zinc finger protein 106
chr12_+_16347665 0.55 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
microsomal glutathione S-transferase 1
chr9_+_27109200 0.54 ENST00000380036.10
TEK receptor tyrosine kinase
chr6_+_44216914 0.54 ENST00000573382.3
ENST00000576476.1
myomixer, myoblast fusion factor
chr16_-_3372666 0.54 ENST00000399974.5
MT-RNR2 like 4
chr19_-_17075418 0.53 ENST00000253669.10
HAUS augmin like complex subunit 8
chr4_+_127730386 0.53 ENST00000281154.6
solute carrier family 25 member 31
chr18_+_23949847 0.53 ENST00000588004.1
laminin subunit alpha 3
chr11_-_74949142 0.52 ENST00000321448.12
ENST00000340360.10
X-ray radiation resistance associated 1
chr2_-_213151590 0.52 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr20_-_1184981 0.52 ENST00000429036.2
transmembrane protein 74B
chr15_+_94297939 0.52 ENST00000357742.9
multiple C2 and transmembrane domain containing 2
chr20_-_3239181 0.51 ENST00000644692.1
ENST00000642402.1
ENST00000644011.1
ENST00000647296.1
solute carrier family 4 member 11
chr5_+_170861990 0.51 ENST00000523189.6
RAN binding protein 17
chr1_-_1206541 0.50 ENST00000328596.10
ENST00000379265.5
ENST00000379268.7
TNF receptor superfamily member 18
chr1_+_204073104 0.50 ENST00000367204.6
SRY-box transcription factor 13
chr7_-_133082032 0.49 ENST00000448878.6
ENST00000262570.10
coiled-coil-helix-coiled-coil-helix domain containing 3
chr15_+_75195613 0.47 ENST00000563905.5
chromosome 15 open reading frame 39
chr10_+_35126791 0.47 ENST00000474362.5
ENST00000374721.7
cAMP responsive element modulator
chr11_-_59866478 0.47 ENST00000257264.4
transcobalamin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.9 3.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.5 2.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.5 2.4 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.5 6.2 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.4 1.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.9 GO:1903413 cellular response to bile acid(GO:1903413)
0.4 2.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 5.8 GO:0006600 creatine metabolic process(GO:0006600)
0.3 3.1 GO:0070995 NADPH oxidation(GO:0070995)
0.3 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 0.9 GO:0061011 hepatic duct development(GO:0061011)
0.3 0.9 GO:0009386 translational attenuation(GO:0009386)
0.3 1.7 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 1.1 GO:1903984 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 1.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 0.7 GO:0071283 regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283)
0.2 0.7 GO:0035445 borate transmembrane transport(GO:0035445) borate transport(GO:0046713)
0.2 2.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 1.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.9 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.8 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 2.0 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 1.4 GO:0060023 soft palate development(GO:0060023)
0.2 0.8 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 1.0 GO:0035803 egg coat formation(GO:0035803)
0.2 0.7 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 3.8 GO:0000052 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.2 1.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 0.6 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 3.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 2.4 GO:0060613 fat pad development(GO:0060613)
0.1 1.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.6 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.7 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.8 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.3 GO:0042946 glucoside transport(GO:0042946) glycoside transport(GO:1901656)
0.1 2.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 1.2 GO:0015705 iodide transport(GO:0015705)
0.1 2.8 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 2.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 8.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 1.6 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:0032445 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.7 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.3 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.8 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.1 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 1.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.9 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 2.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.6 GO:0032328 alanine transport(GO:0032328)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 2.4 GO:0010165 response to X-ray(GO:0010165)
0.0 1.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 2.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 1.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 1.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.3 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.9 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 2.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 2.3 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.7 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.6 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.9 GO:0010039 response to iron ion(GO:0010039)
0.0 0.0 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.3 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.8 GO:0031529 ruffle organization(GO:0031529)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 5.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 1.0 GO:0005914 spot adherens junction(GO:0005914)
0.3 1.4 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.1 GO:0005602 complement component C1 complex(GO:0005602)
0.2 4.3 GO:0005861 troponin complex(GO:0005861)
0.2 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 3.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 3.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 6.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.0 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.3 GO:0097229 sperm end piece(GO:0097229)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.3 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 1.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 3.0 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 5.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.6 GO:0043218 compact myelin(GO:0043218)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 2.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 3.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 2.0 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 4.3 GO:0030017 sarcomere(GO:0030017)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.8 GO:0004111 creatine kinase activity(GO:0004111)
0.7 4.3 GO:0030172 troponin C binding(GO:0030172)
0.6 3.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.5 6.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 3.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.4 2.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 2.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.7 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 1.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.7 GO:0046715 borate transmembrane transporter activity(GO:0046715)
0.2 0.8 GO:0030395 lactose binding(GO:0030395)
0.2 0.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 1.5 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.9 GO:0071253 connexin binding(GO:0071253)
0.2 2.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 2.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.1 0.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 3.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 0.7 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.6 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.7 GO:0035473 lipase binding(GO:0035473)
0.1 0.7 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 3.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 7.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 1.2 GO:0043295 glutathione binding(GO:0043295)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 1.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 2.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0002060 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 2.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 7.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 9.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 8.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 2.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 3.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks