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Illumina Body Map 2 (GSE30611)

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Results for TCF21

Z-value: 1.08

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
TCF21
ENSG00000118526.7 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg38_v1_chr6_+_133889105_1338891200.038.6e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_45322867 5.76 ENST00000221476.4
CKM
creatine kinase, M-type
chr11_+_1922779 4.29 ENST00000641119.1
ENST00000641225.1
ENST00000641787.1
ENST00000397301.5
ENST00000397304.6
ENST00000446240.1
TNNT3
troponin T3, fast skeletal type
chr8_+_85438850 3.29 ENST00000285381.3
CA3
carbonic anhydrase 3
chr7_+_80646436 3.16 ENST00000419819.2
CD36
CD36 molecule
chr16_-_31428325 3.14 ENST00000287490.5
COX6A2
cytochrome c oxidase subunit 6A2
chr7_+_80646347 3.09 ENST00000413265.5
CD36
CD36 molecule
chr1_+_171185293 3.08 ENST00000209929.10
FMO2
flavin containing dimethylaniline monoxygenase 2
chr17_+_47209035 2.42 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
MYL4
myosin light chain 4
chr15_+_57599411 2.17 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr15_+_63048576 2.17 ENST00000559281.6
TPM1
tropomyosin 1
chr2_-_218010202 2.12 ENST00000646520.1
TNS1
tensin 1
chr19_+_11541125 2.10 ENST00000587087.5
CNN1
calponin 1
chr12_-_10723307 1.96 ENST00000279550.11
ENST00000228251.9
YBX3
Y-box binding protein 3
chr3_+_8733779 1.87 ENST00000343849.3
ENST00000397368.2
CAV3
caveolin 3
chr10_-_7619660 1.83 ENST00000613909.4
ITIH5
inter-alpha-trypsin inhibitor heavy chain 5
chr3_+_148865288 1.82 ENST00000296046.4
CPA3
carboxypeptidase A3
chr16_+_55488580 1.77 ENST00000570283.1
MMP2
matrix metallopeptidase 2
chr3_-_9878765 1.75 ENST00000430427.6
ENST00000383817.5
ENST00000679265.1
CIDEC
cell death inducing DFFA like effector c
chr17_+_42851167 1.72 ENST00000613571.1
ENST00000308423.7
AOC3
amine oxidase copper containing 3
chr1_-_162023632 1.67 ENST00000367940.2
OLFML2B
olfactomedin like 2B
chr9_+_97853217 1.66 ENST00000375123.5
FOXE1
forkhead box E1
chr12_+_12891554 1.65 ENST00000014914.6
GPRC5A
G protein-coupled receptor class C group 5 member A
chrX_+_151716023 1.55 ENST00000370350.7
FATE1
fetal and adult testis expressed 1
chr1_+_167094049 1.54 ENST00000361200.7
STYXL2
serine/threonine/tyrosine interacting like 2
chr4_+_168711416 1.53 ENST00000649826.1
PALLD
palladin, cytoskeletal associated protein
chr14_-_106374129 1.50 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr4_+_168712159 1.45 ENST00000510998.5
PALLD
palladin, cytoskeletal associated protein
chr12_-_52519117 1.45 ENST00000551188.5
KRT5
keratin 5
chr9_-_101594918 1.44 ENST00000374806.2
PPP3R2
protein phosphatase 3 regulatory subunit B, beta
chr10_-_95441015 1.42 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
SORBS1
sorbin and SH3 domain containing 1
chr16_+_30372291 1.39 ENST00000568749.5
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_-_101594995 1.37 ENST00000636434.1
PPP3R2
protein phosphatase 3 regulatory subunit B, beta
chrX_-_79367307 1.32 ENST00000373298.7
ITM2A
integral membrane protein 2A
chr12_-_104050112 1.30 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
GLT8D2
glycosyltransferase 8 domain containing 2
chr6_+_116511626 1.29 ENST00000368599.4
CALHM5
calcium homeostasis modulator family member 5
chr10_-_29634964 1.28 ENST00000375398.6
ENST00000355867.8
SVIL
supervillin
chr15_+_63048535 1.26 ENST00000560959.5
TPM1
tropomyosin 1
chr15_+_63048658 1.26 ENST00000560615.5
ENST00000651577.1
TPM1
tropomyosin 1
chr8_+_141413316 1.25 ENST00000329397.6
PTP4A3
protein tyrosine phosphatase 4A3
chr8_+_133017693 1.24 ENST00000518108.1
TG
thyroglobulin
chr1_-_160711803 1.24 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48
CD48 molecule
chr3_+_32391871 1.22 ENST00000465248.1
CMTM7
CKLF like MARVEL transmembrane domain containing 7
chr3_+_32391694 1.21 ENST00000349718.8
CMTM7
CKLF like MARVEL transmembrane domain containing 7
chr2_-_127643212 1.19 ENST00000409286.5
LIMS2
LIM zinc finger domain containing 2
chr21_+_10521569 1.18 ENST00000612957.4
ENST00000427445.6
ENST00000612746.1
ENST00000618007.5
TPTE
transmembrane phosphatase with tensin homology
chr15_+_63048436 1.17 ENST00000334895.10
ENST00000404484.9
ENST00000558910.3
ENST00000317516.12
TPM1
tropomyosin 1
chr7_+_150716603 1.16 ENST00000307194.6
ENST00000611999.4
GIMAP1
GIMAP1-GIMAP5
GTPase, IMAP family member 1
GIMAP1-GIMAP5 readthrough
chr7_-_48029102 1.16 ENST00000297325.9
ENST00000412142.5
ENST00000395572.6
SUN3
Sad1 and UNC84 domain containing 3
chr1_+_212565334 1.13 ENST00000366981.8
ENST00000366987.6
ATF3
activating transcription factor 3
chr8_+_66043413 1.12 ENST00000522619.1
DNAJC5B
DnaJ heat shock protein family (Hsp40) member C5 beta
chr19_-_49325181 1.10 ENST00000454748.7
ENST00000335875.9
ENST00000598828.1
SLC6A16
solute carrier family 6 member 16
chr1_+_99646025 1.09 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr11_+_1870871 1.09 ENST00000417766.5
LSP1
lymphocyte specific protein 1
chr5_-_170389349 1.09 ENST00000274629.9
KCNMB1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr9_+_110090197 1.09 ENST00000480388.1
PALM2AKAP2
PALM2 and AKAP2 fusion
chr17_+_47209338 1.08 ENST00000393450.5
MYL4
myosin light chain 4
chr3_+_32391841 1.08 ENST00000334983.10
CMTM7
CKLF like MARVEL transmembrane domain containing 7
chr1_+_22636577 1.08 ENST00000374642.8
ENST00000438241.1
C1QA
complement C1q A chain
chr22_+_22922594 1.06 ENST00000390331.3
IGLC7
immunoglobulin lambda constant 7
chrX_+_151716068 1.04 ENST00000417321.1
FATE1
fetal and adult testis expressed 1
chr1_-_205422050 1.03 ENST00000367153.9
LEMD1
LEM domain containing 1
chr1_+_172452885 1.03 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr9_+_68356603 1.03 ENST00000396396.6
PGM5
phosphoglucomutase 5
chr6_-_31729260 1.02 ENST00000375789.7
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr8_-_41665261 1.02 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ANK1
ankyrin 1
chr2_+_37950432 1.01 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
RMDN2
regulator of microtubule dynamics 2
chr3_-_52834901 1.00 ENST00000486659.5
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr6_-_31728877 1.00 ENST00000437288.5
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr7_+_134565098 1.00 ENST00000652743.1
AKR1B15
aldo-keto reductase family 1 member B15
chr3_-_52835011 0.99 ENST00000446157.3
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr17_+_79034185 0.99 ENST00000581774.5
C1QTNF1
C1q and TNF related 1
chr18_+_3247778 0.99 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
MYL12A
myosin light chain 12A
chr6_-_31729478 0.96 ENST00000436437.2
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_+_153628393 0.94 ENST00000368696.3
ENST00000292169.6
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr6_-_30690968 0.93 ENST00000376420.9
ENST00000376421.7
NRM
nurim
chr18_+_6834473 0.90 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
ARHGAP28
Rho GTPase activating protein 28
chr19_+_46298382 0.89 ENST00000244303.10
ENST00000533145.5
ENST00000472815.5
HIF3A
hypoxia inducible factor 3 subunit alpha
chr10_+_92689946 0.89 ENST00000282728.10
HHEX
hematopoietically expressed homeobox
chr2_+_37950476 0.87 ENST00000402091.3
RMDN2
regulator of microtubule dynamics 2
chr17_-_7290392 0.87 ENST00000571464.1
YBX2
Y-box binding protein 2
chr11_-_1486763 0.84 ENST00000329957.7
MOB2
MOB kinase activator 2
chr13_-_77919459 0.83 ENST00000643890.1
EDNRB
endothelin receptor type B
chr12_-_50283472 0.83 ENST00000551691.5
ENST00000394943.7
ENST00000341247.8
LIMA1
LIM domain and actin binding 1
chr2_+_219434825 0.83 ENST00000312358.12
SPEG
striated muscle enriched protein kinase
chr3_-_105869035 0.82 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
CBLB
Cbl proto-oncogene B
chr17_-_3513768 0.82 ENST00000570318.1
ENST00000541913.5
SPATA22
spermatogenesis associated 22
chr6_+_28259285 0.82 ENST00000343684.4
NKAPL
NFKB activating protein like
chr2_-_88979016 0.82 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr22_+_37675629 0.81 ENST00000215909.10
LGALS1
galectin 1
chr11_+_47248924 0.81 ENST00000481889.6
ENST00000436778.5
ENST00000531660.5
ENST00000407404.5
NR1H3
nuclear receptor subfamily 1 group H member 3
chr5_+_136028979 0.81 ENST00000442011.7
TGFBI
transforming growth factor beta induced
chr10_+_121989187 0.81 ENST00000513429.5
ENST00000515273.5
ENST00000515603.5
TACC2
transforming acidic coiled-coil containing protein 2
chr21_+_10521536 0.80 ENST00000622113.4
TPTE
transmembrane phosphatase with tensin homology
chr10_+_121989138 0.80 ENST00000369005.6
TACC2
transforming acidic coiled-coil containing protein 2
chr3_-_177197210 0.79 ENST00000431421.5
ENST00000422066.5
ENST00000413084.5
ENST00000673974.1
ENST00000422442.6
TBL1XR1
TBL1X receptor 1
chr2_+_46479565 0.79 ENST00000434431.2
TMEM247
transmembrane protein 247
chr2_-_157439403 0.79 ENST00000418920.5
CYTIP
cytohesin 1 interacting protein
chr3_-_105868964 0.79 ENST00000394030.8
CBLB
Cbl proto-oncogene B
chr8_+_143213192 0.79 ENST00000622500.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr6_-_31729785 0.79 ENST00000416410.6
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr7_+_150737382 0.78 ENST00000358647.5
GIMAP5
GTPase, IMAP family member 5
chr5_-_170389634 0.78 ENST00000521859.1
KCNMB1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr5_-_151093566 0.76 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr6_+_54083423 0.75 ENST00000460844.6
ENST00000370876.6
MLIP
muscular LMNA interacting protein
chr5_-_180802790 0.74 ENST00000504671.1
ENST00000507384.1
ENST00000307826.5
MGAT1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chrX_-_107717054 0.74 ENST00000503515.1
ENST00000372397.6
TSC22D3
TSC22 domain family member 3
chr4_+_122923067 0.73 ENST00000675612.1
ENST00000274008.5
SPATA5
spermatogenesis associated 5
chr2_+_87338511 0.73 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr19_-_12778412 0.72 ENST00000589400.5
ENST00000590839.5
ENST00000592079.5
HOOK2
hook microtubule tethering protein 2
chr22_-_21952827 0.72 ENST00000397495.8
ENST00000263212.10
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent 1F
chr16_+_85902689 0.72 ENST00000563180.1
ENST00000564617.5
ENST00000564803.5
IRF8
interferon regulatory factor 8
chr2_+_218672291 0.72 ENST00000440309.5
ENST00000424080.1
STK36
serine/threonine kinase 36
chr22_+_44031345 0.72 ENST00000444029.5
PARVB
parvin beta
chr7_-_122702912 0.72 ENST00000447240.1
ENST00000434824.2
RNF148
ring finger protein 148
chr8_-_41665200 0.71 ENST00000335651.6
ANK1
ankyrin 1
chr3_-_177197248 0.71 ENST00000427349.5
ENST00000352800.10
TBL1XR1
TBL1X receptor 1
chr8_+_25459190 0.71 ENST00000380665.3
ENST00000330560.8
CDCA2
cell division cycle associated 2
chr22_-_23580223 0.70 ENST00000249053.3
ENST00000330377.3
ENST00000438703.1
IGLL1
immunoglobulin lambda like polypeptide 1
chr2_+_230416239 0.70 ENST00000409824.5
ENST00000409341.5
ENST00000409112.5
SP100
SP100 nuclear antigen
chr20_+_31739260 0.70 ENST00000340513.4
ENST00000300403.11
TPX2
TPX2 microtubule nucleation factor
chr11_+_47248885 0.69 ENST00000395397.7
ENST00000405576.5
NR1H3
nuclear receptor subfamily 1 group H member 3
chr7_+_121076570 0.69 ENST00000443817.1
CPED1
cadherin like and PC-esterase domain containing 1
chr19_-_39833615 0.69 ENST00000593685.5
ENST00000600611.5
DYRK1B
dual specificity tyrosine phosphorylation regulated kinase 1B
chr17_+_4583998 0.69 ENST00000338859.8
SMTNL2
smoothelin like 2
chr1_+_145927105 0.68 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L-AS1
ENSG00000280778.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr6_-_11382247 0.68 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr2_+_56183973 0.68 ENST00000407595.3
CCDC85A
coiled-coil domain containing 85A
chr9_+_27109135 0.68 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr2_+_102104563 0.68 ENST00000409589.5
ENST00000409329.5
IL1R1
interleukin 1 receptor type 1
chr14_-_106811131 0.67 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr4_-_46909235 0.67 ENST00000505102.1
ENST00000355591.8
COX7B2
cytochrome c oxidase subunit 7B2
chr2_+_230416156 0.67 ENST00000427101.6
SP100
SP100 nuclear antigen
chr3_-_177197429 0.67 ENST00000457928.7
TBL1XR1
TBL1X receptor 1
chr1_-_23531206 0.66 ENST00000361729.3
E2F2
E2F transcription factor 2
chr6_+_18387326 0.66 ENST00000259939.4
RNF144B
ring finger protein 144B
chr15_+_43792839 0.65 ENST00000409614.1
SERF2
small EDRK-rich factor 2
chr13_-_77919390 0.65 ENST00000475537.2
ENST00000646605.1
EDNRB
endothelin receptor type B
chr11_-_74949079 0.64 ENST00000528219.5
ENST00000684022.1
ENST00000531852.5
XRRA1
X-ray radiation resistance associated 1
chr11_+_827545 0.64 ENST00000528542.6
CRACR2B
calcium release activated channel regulator 2B
chr11_-_74949114 0.63 ENST00000527087.5
XRRA1
X-ray radiation resistance associated 1
chr1_+_186296267 0.63 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
PRG4
proteoglycan 4
chr8_-_94949350 0.63 ENST00000448464.6
ENST00000342697.5
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr2_+_218672027 0.62 ENST00000392105.7
ENST00000455724.5
ENST00000295709.8
STK36
serine/threonine kinase 36
chr11_-_74949020 0.62 ENST00000525407.5
XRRA1
X-ray radiation resistance associated 1
chr12_+_16347637 0.62 ENST00000543076.5
ENST00000396210.8
MGST1
microsomal glutathione S-transferase 1
chr2_+_90234809 0.62 ENST00000443397.5
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr11_+_33258304 0.61 ENST00000531504.5
ENST00000456517.2
HIPK3
homeodomain interacting protein kinase 3
chr20_+_38581186 0.61 ENST00000373348.4
ENST00000537425.2
ENST00000416116.2
ADIG
adipogenin
chr7_-_76627240 0.61 ENST00000275569.8
ENST00000310842.9
POMZP3
POM121 and ZP3 fusion
chr9_-_127778659 0.61 ENST00000314830.13
SH2D3C
SH2 domain containing 3C
chr19_-_33225844 0.61 ENST00000253188.8
SLC7A10
solute carrier family 7 member 10
chr2_-_233854566 0.61 ENST00000432087.5
ENST00000441687.5
ENST00000414924.5
HJURP
Holliday junction recognition protein
chr12_+_8697875 0.61 ENST00000357529.7
RIMKLB
ribosomal modification protein rimK like family member B
chr1_+_24556087 0.60 ENST00000374392.3
NCMAP
non-compact myelin associated protein
chr12_+_8697945 0.60 ENST00000535829.6
RIMKLB
ribosomal modification protein rimK like family member B
chr2_+_230416190 0.60 ENST00000340126.9
ENST00000432979.5
SP100
SP100 nuclear antigen
chr11_-_88175432 0.60 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38
RAB38, member RAS oncogene family
chr13_-_103066411 0.59 ENST00000245312.5
SLC10A2
solute carrier family 10 member 2
chr15_+_89243945 0.59 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FANCI
FA complementation group I
chr13_-_41061373 0.59 ENST00000405737.2
ELF1
E74 like ETS transcription factor 1
chr11_+_827913 0.59 ENST00000525077.2
CRACR2B
calcium release activated channel regulator 2B
chr17_-_7394800 0.59 ENST00000574401.5
PLSCR3
phospholipid scramblase 3
chrX_-_11427725 0.59 ENST00000380736.5
ARHGAP6
Rho GTPase activating protein 6
chr4_-_46909206 0.58 ENST00000396533.5
COX7B2
cytochrome c oxidase subunit 7B2
chr1_+_27935022 0.58 ENST00000411604.5
ENST00000373888.8
SMPDL3B
sphingomyelin phosphodiesterase acid like 3B
chr15_-_42457513 0.58 ENST00000565611.5
ENST00000263805.8
ZNF106
zinc finger protein 106
chr11_-_16397521 0.58 ENST00000533411.5
SOX6
SRY-box transcription factor 6
chr20_-_3682218 0.58 ENST00000379861.8
ADAM33
ADAM metallopeptidase domain 33
chr13_-_77918788 0.57 ENST00000626030.1
EDNRB
endothelin receptor type B
chr1_-_201469151 0.57 ENST00000367311.5
ENST00000367309.1
PHLDA3
pleckstrin homology like domain family A member 3
chr17_-_7394514 0.57 ENST00000571802.1
ENST00000619711.5
ENST00000576201.5
ENST00000573213.1
ENST00000324822.15
PLSCR3
phospholipid scramblase 3
chrX_+_48574477 0.56 ENST00000376759.8
RBM3
RNA binding motif protein 3
chr17_-_15262537 0.56 ENST00000395936.7
ENST00000675819.1
ENST00000674707.1
ENST00000675854.1
ENST00000426385.4
ENST00000395938.7
ENST00000612492.5
ENST00000675808.1
PMP22
peripheral myelin protein 22
chr15_-_78811415 0.56 ENST00000388820.5
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr8_-_19682576 0.56 ENST00000332246.10
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr22_+_38656627 0.56 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
CBY1
chibby family member 1, beta catenin antagonist
chr17_-_41102209 0.56 ENST00000440582.1
KRTAP4-16
keratin associated protein 4-16
chr11_+_59142811 0.55 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111A
FAM111 trypsin like peptidase A
chr8_-_9150648 0.55 ENST00000310455.4
PPP1R3B
protein phosphatase 1 regulatory subunit 3B
chr3_-_169146527 0.55 ENST00000475754.5
ENST00000484519.5
MECOM
MDS1 and EVI1 complex locus
chr15_-_42457556 0.55 ENST00000565948.1
ZNF106
zinc finger protein 106
chr12_+_16347665 0.55 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
MGST1
microsomal glutathione S-transferase 1
chr9_+_27109200 0.54 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr6_+_44216914 0.54 ENST00000573382.3
ENST00000576476.1
MYMX
myomixer, myoblast fusion factor
chr16_-_3372666 0.54 ENST00000399974.5
MTRNR2L4
MT-RNR2 like 4
chr19_-_17075418 0.53 ENST00000253669.10
HAUS8
HAUS augmin like complex subunit 8
chr4_+_127730386 0.53 ENST00000281154.6
SLC25A31
solute carrier family 25 member 31
chr18_+_23949847 0.53 ENST00000588004.1
LAMA3
laminin subunit alpha 3
chr11_-_74949142 0.52 ENST00000321448.12
ENST00000340360.10
XRRA1
X-ray radiation resistance associated 1
chr2_-_213151590 0.52 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKZF2
IKAROS family zinc finger 2
chr20_-_1184981 0.52 ENST00000429036.2
TMEM74B
transmembrane protein 74B
chr15_+_94297939 0.52 ENST00000357742.9
MCTP2
multiple C2 and transmembrane domain containing 2
chr20_-_3239181 0.51 ENST00000644692.1
ENST00000642402.1
ENST00000644011.1
ENST00000647296.1
SLC4A11
solute carrier family 4 member 11
chr5_+_170861990 0.51 ENST00000523189.6
RANBP17
RAN binding protein 17
chr1_-_1206541 0.50 ENST00000328596.10
ENST00000379265.5
ENST00000379268.7
TNFRSF18
TNF receptor superfamily member 18
chr1_+_204073104 0.50 ENST00000367204.6
SOX13
SRY-box transcription factor 13
chr7_-_133082032 0.49 ENST00000448878.6
ENST00000262570.10
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr15_+_75195613 0.47 ENST00000563905.5
C15orf39
chromosome 15 open reading frame 39
chr10_+_35126791 0.47 ENST00000474362.5
ENST00000374721.7
CREM
cAMP responsive element modulator
chr11_-_59866478 0.47 ENST00000257264.4
TCN1
transcobalamin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.9 3.5 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.5 2.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.5 2.4 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.5 6.2 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.4 1.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.9 GO:1903413 cellular response to bile acid(GO:1903413)
0.4 2.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 5.8 GO:0006600 creatine metabolic process(GO:0006600)
0.3 3.1 GO:0070995 NADPH oxidation(GO:0070995)
0.3 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 0.9 GO:0061011 hepatic duct development(GO:0061011)
0.3 0.9 GO:0009386 translational attenuation(GO:0009386)
0.3 1.7 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 1.1 GO:1903984 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 1.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 0.7 GO:0071283 regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283)
0.2 0.7 GO:0035445 borate transmembrane transport(GO:0035445) borate transport(GO:0046713)
0.2 2.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 1.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.9 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.8 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 2.0 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 1.4 GO:0060023 soft palate development(GO:0060023)
0.2 0.8 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 1.0 GO:0035803 egg coat formation(GO:0035803)
0.2 0.7 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 3.8 GO:0000052 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.2 1.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 0.6 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 3.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 2.4 GO:0060613 fat pad development(GO:0060613)
0.1 1.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.6 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.7 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.8 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.3 GO:0042946 glucoside transport(GO:0042946) glycoside transport(GO:1901656)
0.1 2.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 1.2 GO:0015705 iodide transport(GO:0015705)
0.1 2.8 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 2.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 8.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 1.6 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:0032445 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.7 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.3 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.8 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.1 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 1.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.9 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 2.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.6 GO:0032328 alanine transport(GO:0032328)
0.0 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 2.4 GO:0010165 response to X-ray(GO:0010165)
0.0 1.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 2.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 1.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.6 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 1.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.3 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.9 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 2.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 2.3 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.7 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.6 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.9 GO:0010039 response to iron ion(GO:0010039)
0.0 0.0 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.3 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.8 GO:0031529 ruffle organization(GO:0031529)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 5.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 1.0 GO:0005914 spot adherens junction(GO:0005914)
0.3 1.4 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.1 GO:0005602 complement component C1 complex(GO:0005602)
0.2 4.3 GO:0005861 troponin complex(GO:0005861)
0.2 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 3.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 3.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 6.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.0 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.3 GO:0097229 sperm end piece(GO:0097229)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.3 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 1.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 3.0 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 5.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.6 GO:0043218 compact myelin(GO:0043218)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 2.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 3.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 2.0 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 4.3 GO:0030017 sarcomere(GO:0030017)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.7 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.8 GO:0004111 creatine kinase activity(GO:0004111)
0.7 4.3 GO:0030172 troponin C binding(GO:0030172)
0.6 3.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.5 6.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 3.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.4 2.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 2.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.7 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 1.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.7 GO:0046715 borate transmembrane transporter activity(GO:0046715)
0.2 0.8 GO:0030395 lactose binding(GO:0030395)
0.2 0.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 1.5 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.9 GO:0071253 connexin binding(GO:0071253)
0.2 2.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 2.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.1 0.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 3.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 0.7 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.6 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.7 GO:0035473 lipase binding(GO:0035473)
0.1 0.7 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 3.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 7.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 1.2 GO:0043295 glutathione binding(GO:0043295)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 1.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 2.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0002060 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 2.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 2.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 7.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 9.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 8.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 2.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 3.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks