ISMARA results: TCF7L1

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Illumina Body Map 2 (GSE30611)

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Results for TCF7L1

Z-value: 1.31

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Transcription factors associated with TCF7L1

Gene Symbol	Gene ID	Gene Info
TCF7L1 Ensembl NCBI GeneCards UniProt	ENSG00000152284.5	transcription factor 7 like 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TCF7L1	hg38_v1_chr2_+_85133376_85133474	-0.03	8.9e-01	Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_-_106975452 Show fit	4.89	ENST00000619869.1 ENST00000619133.4	CD24 Ensembl NCBI GeneCards UniProt Show fit	CD24 molecule
chr6_-_106975309 Show fit	4.57	ENST00000615659.1	CD24 Ensembl NCBI GeneCards UniProt Show fit	CD24 molecule
chr7_+_116210501 Show fit	4.22	ENST00000455989.1 ENST00000358204.9	TES Ensembl NCBI GeneCards UniProt Show fit	testin LIM domain protein
chr15_+_40844018 Show fit	3.77	ENST00000344051.8 ENST00000562057.6	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr21_-_44910630 Show fit	3.68	ENST00000320216.10 ENST00000397852.5	ITGB2 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 2
chr1_-_153550083 Show fit	3.65	ENST00000368714.1	S100A4 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A4
chr5_+_134114673 Show fit	3.61	ENST00000342854.10 ENST00000395029.5	TCF7 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7
chr8_+_22161788 Show fit	3.40	ENST00000521315.5 ENST00000437090.6 ENST00000679463.1 ENST00000520605.5 ENST00000522109.5 ENST00000524255.5 ENST00000523296.1	SFTPC Ensembl NCBI GeneCards UniProt Show fit	surfactant protein C
chr6_-_106974721 Show fit	3.33	ENST00000606017.2 ENST00000620405.1	CD24 Ensembl NCBI GeneCards UniProt Show fit	CD24 molecule
chr17_-_47957824 Show fit	3.25	ENST00000300557.3	PRR15L Ensembl NCBI GeneCards UniProt Show fit	proline rich 15 like
chr4_+_77157189 Show fit	3.18	ENST00000316355.10 ENST00000502280.5	CCNG2 Ensembl NCBI GeneCards UniProt Show fit	cyclin G2
chr17_-_40937445 Show fit	3.14	ENST00000436344.7 ENST00000485751.1	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chrX_-_154371210 Show fit	3.02	ENST00000369856.8 ENST00000422373.6 ENST00000360319.9	FLNA Ensembl NCBI GeneCards UniProt Show fit	filamin A
chr17_-_40937641 Show fit	2.96	ENST00000209718.8	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chr21_+_29299368 Show fit	2.95	ENST00000399921.5	BACH1 Ensembl NCBI GeneCards UniProt Show fit	BTB domain and CNC homolog 1
chr17_-_39864140 Show fit	2.93	ENST00000623724.3 ENST00000439167.6 ENST00000377945.7 ENST00000394189.6 ENST00000377944.7 ENST00000377958.6 ENST00000535189.5 ENST00000377952.6	IKZF3 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 3
chr18_+_3450036 Show fit	2.90	ENST00000546979.5 ENST00000343820.10 ENST00000551402.1 ENST00000577543.5	TGIF1 Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 1
chr8_+_22161655 Show fit	2.90	ENST00000318561.7	SFTPC Ensembl NCBI GeneCards UniProt Show fit	surfactant protein C
chr14_-_64942783 Show fit	2.90	ENST00000612794.1	GPX2 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 2
chr7_+_73830988 Show fit	2.90	ENST00000340958.4	CLDN4 Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr14_+_75279961 Show fit	2.80	ENST00000557139.1	FOS Ensembl NCBI GeneCards UniProt Show fit	Fos proto-oncogene, AP-1 transcription factor subunit
chr4_-_121072519 Show fit	2.79	ENST00000379692.9	NDNF Ensembl NCBI GeneCards UniProt Show fit	neuron derived neurotrophic factor
chr7_+_120989030 Show fit	2.77	ENST00000428526.5	CPED1 Ensembl NCBI GeneCards UniProt Show fit	cadherin like and PC-esterase domain containing 1
chrX_+_72069659 Show fit	2.71	ENST00000631375.1	NHSL2 Ensembl NCBI GeneCards UniProt Show fit	NHS like 2
chr6_-_11778781 Show fit	2.70	ENST00000414691.8 ENST00000229583.9	ADTRP Ensembl NCBI GeneCards UniProt Show fit	androgen dependent TFPI regulating protein
chr5_-_157575767 Show fit	2.67	ENST00000257527.9	ADAM19 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 19
chr15_+_40844506 Show fit	2.61	ENST00000568580.5	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr14_+_75280078 Show fit	2.54	ENST00000555347.1	FOS Ensembl NCBI GeneCards UniProt Show fit	Fos proto-oncogene, AP-1 transcription factor subunit
chr17_+_77451244 Show fit	2.53	ENST00000591088.5	SEPTIN9 Ensembl NCBI GeneCards UniProt Show fit	septin 9
chr18_+_3449817 Show fit	2.40	ENST00000407501.6	TGIF1 Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 1
chr12_-_31324129 Show fit	2.40	ENST00000454658.6	SINHCAF Ensembl NCBI GeneCards UniProt Show fit	SIN3-HDAC complex associated factor
chr7_+_80602200 Show fit	2.38	ENST00000534394.5	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr9_-_35650902 Show fit	2.37	ENST00000259608.8 ENST00000618781.1	SIT1 Ensembl NCBI GeneCards UniProt Show fit	signaling threshold regulating transmembrane adaptor 1
chr6_-_106975616 Show fit	2.36	ENST00000610952.1	CD24 Ensembl NCBI GeneCards UniProt Show fit	CD24 molecule
chr7_+_80602150 Show fit	2.32	ENST00000309881.11	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr11_-_88175432 Show fit	2.31	ENST00000531138.1 ENST00000526372.1 ENST00000243662.11	RAB38 Ensembl NCBI GeneCards UniProt Show fit	RAB38, member RAS oncogene family
chr17_-_39864304 Show fit	2.28	ENST00000346872.8	IKZF3 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 3
chr19_-_11339573 Show fit	2.25	ENST00000222120.8	RAB3D Ensembl NCBI GeneCards UniProt Show fit	RAB3D, member RAS oncogene family
chr5_-_176537361 Show fit	2.17	ENST00000274811.9	RNF44 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 44
chr17_-_39864126 Show fit	2.14	ENST00000351680.7 ENST00000346243.7 ENST00000350532.7 ENST00000467757.5 ENST00000439016.2	IKZF3 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 3
chr5_-_139389905 Show fit	2.09	ENST00000302125.9	MZB1 Ensembl NCBI GeneCards UniProt Show fit	marginal zone B and B1 cell specific protein
chr15_+_40844171 Show fit	2.08	ENST00000563656.5	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr8_-_33567118 Show fit	2.07	ENST00000256257.2	RNF122 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 122
chr17_-_7394514 Show fit	1.95	ENST00000571802.1 ENST00000619711.5 ENST00000576201.5 ENST00000573213.1 ENST00000324822.15	PLSCR3 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 3
chr5_-_157575741 Show fit	1.94	ENST00000517905.1	ADAM19 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 19
chr2_-_207166818 Show fit	1.92	ENST00000423015.5	KLF7 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 7
chr10_+_69801892 Show fit	1.87	ENST00000398978.8 ENST00000645393.2 ENST00000354547.7 ENST00000674121.1 ENST00000673842.1 ENST00000520267.5	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr7_+_120988683 Show fit	1.82	ENST00000340646.9 ENST00000310396.10	CPED1 Ensembl NCBI GeneCards UniProt Show fit	cadherin like and PC-esterase domain containing 1
chr11_+_36296281 Show fit	1.82	ENST00000530639.6	PRR5L Ensembl NCBI GeneCards UniProt Show fit	proline rich 5 like
chr1_-_65067707 Show fit	1.80	ENST00000672099.1 ENST00000671954.1 ENST00000672434.1 ENST00000673502.1 ENST00000672751.1	JAK1 Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr17_-_7394240 Show fit	1.80	ENST00000576362.5 ENST00000571078.5	PLSCR3 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 3
chr1_+_222928415 Show fit	1.79	ENST00000284476.7	DISP1 Ensembl NCBI GeneCards UniProt Show fit	dispatched RND transporter family member 1
chr10_-_14572123 Show fit	1.78	ENST00000378465.7 ENST00000452706.6 ENST00000622567.4 ENST00000378458.6	FAM107B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member B
chr14_-_34875348 Show fit	1.77	ENST00000360310.6	BAZ1A Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 1A
chrX_+_101390824 Show fit	1.75	ENST00000427805.6 ENST00000614077.4	RPL36A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L36a
chr11_+_65572349 Show fit	1.72	ENST00000316409.2 ENST00000449319.2 ENST00000530349.2	FAM89B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 89 member B
chr10_+_69802424 Show fit	1.69	ENST00000673802.2 ENST00000517713.5 ENST00000520133.5 ENST00000522165.5 ENST00000673641.2 ENST00000673628.2	COL13A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type XIII alpha 1 chain
chr4_+_2818155 Show fit	1.69	ENST00000511747.6	SH3BP2 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain binding protein 2
chr20_+_57391388 Show fit	1.67	ENST00000356208.10 ENST00000440234.6	RBM38 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 38
chr7_-_140176970 Show fit	1.65	ENST00000397560.7	KDM7A Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 7A
chr7_+_80646436 Show fit	1.65	ENST00000419819.2	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr14_-_34874887 Show fit	1.64	ENST00000382422.6	BAZ1A Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 1A
chr11_-_5234475 Show fit	1.62	ENST00000292901.7 ENST00000650601.1 ENST00000417377.1	HBD Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit delta
chr7_+_150379316 Show fit	1.60	ENST00000483664.5 ENST00000329630.10	ENSG00000284048.2 Ensembl NCBI GeneCards UniProt Show fit ZNF775 Ensembl NCBI GeneCards UniProt Show fit	novel transcript zinc finger protein 775
chr6_-_27473058 Show fit	1.60	ENST00000683788.1 ENST00000211936.10	ZNF184 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 184
chr15_+_75843438 Show fit	1.59	ENST00000267938.9	UBE2Q2 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 Q2
chr3_-_47781837 Show fit	1.59	ENST00000254480.10	SMARCC1 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
chr12_+_1629197 Show fit	1.58	ENST00000397196.7	WNT5B Ensembl NCBI GeneCards UniProt Show fit	Wnt family member 5B
chr7_-_149028651 Show fit	1.58	ENST00000286091.9	PDIA4 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 4
chr3_+_189631373 Show fit	1.53	ENST00000264731.8 ENST00000418709.6 ENST00000320472.9 ENST00000392460.7 ENST00000440651.6	TP63 Ensembl NCBI GeneCards UniProt Show fit	tumor protein p63
chr17_-_7394800 Show fit	1.52	ENST00000574401.5	PLSCR3 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 3
chr7_-_149028452 Show fit	1.52	ENST00000413966.1 ENST00000652332.1	PDIA4 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 4
chr15_+_81000913 Show fit	1.51	ENST00000267984.4	TLNRD1 Ensembl NCBI GeneCards UniProt Show fit	talin rod domain containing 1
chr10_+_21524670 Show fit	1.47	ENST00000631589.1	MLLT10 Ensembl NCBI GeneCards UniProt Show fit	MLLT10 histone lysine methyltransferase DOT1L cofactor
chr7_+_80646305 Show fit	1.47	ENST00000426978.5 ENST00000432207.5	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr6_-_151391539 Show fit	1.45	ENST00000325144.5	ZBTB2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 2
chr13_+_23570370 Show fit	1.44	ENST00000403372.6 ENST00000248484.9	TNFRSF19 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 19
chr12_+_55931148 Show fit	1.43	ENST00000549629.5 ENST00000555218.5 ENST00000331886.10	DGKA Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase alpha
chr14_+_58634055 Show fit	1.41	ENST00000556859.5 ENST00000421793.5	DACT1 Ensembl NCBI GeneCards UniProt Show fit	dishevelled binding antagonist of beta catenin 1
chr15_+_64841873 Show fit	1.41	ENST00000616065.4 ENST00000323544.5	PLEKHO2 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing O2
chr2_-_39121000 Show fit	1.40	ENST00000402219.8	SOS1 Ensembl NCBI GeneCards UniProt Show fit	SOS Ras/Rac guanine nucleotide exchange factor 1
chr1_+_109548567 Show fit	1.38	ENST00000369851.7	GNAI3 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha i3
chr4_-_102345196 Show fit	1.38	ENST00000683412.1 ENST00000682227.1	SLC39A8 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 8
chr12_+_8913875 Show fit	1.37	ENST00000538657.5	PHC1 Ensembl NCBI GeneCards UniProt Show fit	polyhomeotic homolog 1
chr15_-_101252040 Show fit	1.36	ENST00000254190.4	CHSY1 Ensembl NCBI GeneCards UniProt Show fit	chondroitin sulfate synthase 1
chr1_+_100351698 Show fit	1.32	ENST00000644676.1	CDC14A Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14A
chr6_-_27472681 Show fit	1.32	ENST00000377419.1	ZNF184 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 184
chr15_+_75843307 Show fit	1.31	ENST00000569423.5	UBE2Q2 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 Q2
chr7_-_27174274 Show fit	1.30	ENST00000283921.5	HOXA10 Ensembl NCBI GeneCards UniProt Show fit	homeobox A10
chrX_+_101390976 Show fit	1.29	ENST00000392994.7	RPL36A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L36a
chr14_+_20745880 Show fit	1.27	ENST00000326842.3	EDDM3A Ensembl NCBI GeneCards UniProt Show fit	epididymal protein 3A
chr15_+_40844064 Show fit	1.25	ENST00000568823.5	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr11_+_66231794 Show fit	1.24	ENST00000528935.1	PACS1 Ensembl NCBI GeneCards UniProt Show fit	phosphofurin acidic cluster sorting protein 1
chr7_-_27180230 Show fit	1.22	ENST00000396344.4	HOXA10 Ensembl NCBI GeneCards UniProt Show fit	homeobox A10
chr19_+_55600277 Show fit	1.21	ENST00000301073.4	ZNF524 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 524
chr21_+_29300111 Show fit	1.20	ENST00000451655.5	BACH1 Ensembl NCBI GeneCards UniProt Show fit	BTB domain and CNC homolog 1
chr7_-_148884159 Show fit	1.18	ENST00000478654.5 ENST00000460911.5 ENST00000350995.6	EZH2 Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr13_-_71867192 Show fit	1.18	ENST00000611519.4 ENST00000620444.4 ENST00000613252.5	DACH1 Ensembl NCBI GeneCards UniProt Show fit	dachshund family transcription factor 1
chr22_-_31292445 Show fit	1.17	ENST00000402249.7 ENST00000215912.10 ENST00000443175.1 ENST00000441972.5	PIK3IP1 Ensembl NCBI GeneCards UniProt Show fit	phosphoinositide-3-kinase interacting protein 1
chrX_-_100928903 Show fit	1.17	ENST00000372956.3	XKRX Ensembl NCBI GeneCards UniProt Show fit	XK related X-linked
chrX_+_101391202 Show fit	1.17	ENST00000471855.1	RPL36A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L36a
chr8_+_101492751 Show fit	1.16	ENST00000395927.1	GRHL2 Ensembl NCBI GeneCards UniProt Show fit	grainyhead like transcription factor 2
chr2_-_9003657 Show fit	1.16	ENST00000462696.1 ENST00000305997.8	MBOAT2 Ensembl NCBI GeneCards UniProt Show fit	membrane bound O-acyltransferase domain containing 2
chr2_+_176129680 Show fit	1.16	ENST00000429017.2 ENST00000313173.6	HOXD8 Ensembl NCBI GeneCards UniProt Show fit	homeobox D8
chr14_+_21852457 Show fit	1.13	ENST00000390435.1	TRAV8-3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 8-3
chr2_+_169066994 Show fit	1.13	ENST00000357546.6 ENST00000432060.6	DHRS9 Ensembl NCBI GeneCards UniProt Show fit	dehydrogenase/reductase 9
chr6_+_143608170 Show fit	1.13	ENST00000427704.6 ENST00000305766.10	PHACTR2 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 2
chr2_+_227813834 Show fit	1.12	ENST00000358813.5 ENST00000409189.7	CCL20 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 20
chr3_+_141387801 Show fit	1.12	ENST00000514251.5	ZBTB38 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr10_+_21524627 Show fit	1.10	ENST00000651097.1	MLLT10 Ensembl NCBI GeneCards UniProt Show fit	MLLT10 histone lysine methyltransferase DOT1L cofactor
chr15_-_51751525 Show fit	1.10	ENST00000454181.6	LYSMD2 Ensembl NCBI GeneCards UniProt Show fit	LysM domain containing 2
chr11_-_95232514 Show fit	1.09	ENST00000634898.1 ENST00000542176.1 ENST00000278499.6	SESN3 Ensembl NCBI GeneCards UniProt Show fit	sestrin 3
chr1_+_182839338 Show fit	1.09	ENST00000367549.4	DHX9 Ensembl NCBI GeneCards UniProt Show fit	DExH-box helicase 9
chrX_-_19747574 Show fit	1.07	ENST00000432234.5	SH3KBP1 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing kinase binding protein 1
chr6_-_33580229 Show fit	1.07	ENST00000374467.4 ENST00000442998.6 ENST00000360661.9	BAK1 Ensembl NCBI GeneCards UniProt Show fit	BCL2 antagonist/killer 1
chr14_+_21894433 Show fit	1.06	ENST00000390438.2	TRAV8-4 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 8-4
chr7_-_27174253 Show fit	1.05	ENST00000613671.1	HOXA10 Ensembl NCBI GeneCards UniProt Show fit	homeobox A10
chr8_-_101206064 Show fit	1.04	ENST00000518336.5 ENST00000520454.1	ZNF706 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 706
chr13_+_75760362 Show fit	1.04	ENST00000534657.5	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr19_-_7926106 Show fit	1.03	ENST00000318978.6	CTXN1 Ensembl NCBI GeneCards UniProt Show fit	cortexin 1
chrX_+_101391000 Show fit	1.03	ENST00000553110.8 ENST00000409338.5 ENST00000409170.3	RPL36A Ensembl NCBI GeneCards UniProt Show fit RPL36A-HNRNPH2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L36a RPL36A-HNRNPH2 readthrough
chr3_+_179562886 Show fit	1.02	ENST00000450518.6 ENST00000392662.5 ENST00000429709.7 ENST00000490364.1	ACTL6A Ensembl NCBI GeneCards UniProt Show fit	actin like 6A
chr15_+_74782574 Show fit	1.02	ENST00000567123.1 ENST00000569462.5	CSK Ensembl NCBI GeneCards UniProt Show fit	C-terminal Src kinase
chr14_-_22982258 Show fit	1.01	ENST00000555074.1 ENST00000361265.8	ENSG00000259132.1 Ensembl NCBI GeneCards UniProt Show fit AJUBA Ensembl NCBI GeneCards UniProt Show fit	novel protein ajuba LIM protein
chr8_-_17246390 Show fit	1.01	ENST00000520178.3	CNOT7 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 7
chr8_-_69833338 Show fit	0.98	ENST00000524945.5	SLCO5A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 5A1
chr7_-_148884266 Show fit	0.97	ENST00000483967.5 ENST00000320356.7	EZH2 Ensembl NCBI GeneCards UniProt Show fit	enhancer of zeste 2 polycomb repressive complex 2 subunit
chr20_+_41136944 Show fit	0.96	ENST00000244007.7	PLCG1 Ensembl NCBI GeneCards UniProt Show fit	phospholipase C gamma 1
chr8_+_38787218 Show fit	0.96	ENST00000317827.9 ENST00000276520.12	TACC1 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 1
chr2_-_37324826 Show fit	0.95	ENST00000234179.8	PRKD3 Ensembl NCBI GeneCards UniProt Show fit	protein kinase D3
chr7_+_80646347 Show fit	0.92	ENST00000413265.5	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr11_-_117876612 Show fit	0.90	ENST00000584230.1 ENST00000526014.6 ENST00000584394.5 ENST00000614497.5 ENST00000532984.1	FXYD6 Ensembl NCBI GeneCards UniProt Show fit FXYD6-FXYD2 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 6 FXYD6-FXYD2 readthrough
chr15_+_74782069 Show fit	0.90	ENST00000220003.14 ENST00000439220.6	CSK Ensembl NCBI GeneCards UniProt Show fit	C-terminal Src kinase
chr10_-_14572313 Show fit	0.89	ENST00000479731.5 ENST00000468492.5	FAM107B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member B
chr2_-_207167220 Show fit	0.89	ENST00000421199.5 ENST00000457962.5	KLF7 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 7
chr8_+_30095649 Show fit	0.88	ENST00000518192.5	LEPROTL1 Ensembl NCBI GeneCards UniProt Show fit	leptin receptor overlapping transcript like 1
chr4_-_7939789 Show fit	0.87	ENST00000420658.6 ENST00000358461.6	AFAP1 Ensembl NCBI GeneCards UniProt Show fit	actin filament associated protein 1
chr17_-_65560296 Show fit	0.86	ENST00000585045.1 ENST00000611991.1	AXIN2 Ensembl NCBI GeneCards UniProt Show fit	axin 2
chr2_-_159616442 Show fit	0.85	ENST00000541068.6 ENST00000392783.7 ENST00000392782.5	BAZ2B Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 2B
chr1_-_6419903 Show fit	0.85	ENST00000377836.8 ENST00000487437.5 ENST00000489730.1 ENST00000377834.8	HES2 Ensembl NCBI GeneCards UniProt Show fit	hes family bHLH transcription factor 2
chr12_-_49188811 Show fit	0.84	ENST00000295766.9	TUBA1A Ensembl NCBI GeneCards UniProt Show fit	tubulin alpha 1a
chr9_-_120926752 Show fit	0.83	ENST00000373887.8	TRAF1 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 1
chr7_+_114416286 Show fit	0.83	ENST00000635534.1	FOXP2 Ensembl NCBI GeneCards UniProt Show fit	forkhead box P2
chr18_+_6729698 Show fit	0.82	ENST00000383472.9	ARHGAP28 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 28
chr1_+_43650466 Show fit	0.82	ENST00000463151.5	KDM4A Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 4A
chrX_-_40097403 Show fit	0.82	ENST00000397354.7	BCOR Ensembl NCBI GeneCards UniProt Show fit	BCL6 corepressor
chr5_+_72816643 Show fit	0.81	ENST00000337273.10 ENST00000523768.5	TNPO1 Ensembl NCBI GeneCards UniProt Show fit	transportin 1
chr8_-_42377227 Show fit	0.80	ENST00000220812.3	DKK4 Ensembl NCBI GeneCards UniProt Show fit	dickkopf WNT signaling pathway inhibitor 4
chr2_+_10043524 Show fit	0.78	ENST00000305883.6	KLF11 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 11
chr12_+_53097656 Show fit	0.78	ENST00000301464.4	IGFBP6 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 6
chr15_+_64841940 Show fit	0.78	ENST00000437723.1	ENSG00000249240.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr19_-_40285395 Show fit	0.75	ENST00000424901.5 ENST00000578123.5	AKT2 Ensembl NCBI GeneCards UniProt Show fit	AKT serine/threonine kinase 2
chr5_+_132257670 Show fit	0.75	ENST00000253754.8 ENST00000379018.7	PDLIM4 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 4
chr12_+_55931447 Show fit	0.75	ENST00000549368.5	DGKA Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase alpha
chr17_-_65561640 Show fit	0.74	ENST00000618960.4 ENST00000307078.10	AXIN2 Ensembl NCBI GeneCards UniProt Show fit	axin 2
chr2_+_9843426 Show fit	0.72	ENST00000625239.2 ENST00000263663.10	TAF1B Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor, RNA polymerase I subunit B
chr12_+_103965835 Show fit	0.70	ENST00000266775.13 ENST00000544861.5	TDG Ensembl NCBI GeneCards UniProt Show fit	thymine DNA glycosylase
chr4_-_68349750 Show fit	0.70	ENST00000579690.5	YTHDC1 Ensembl NCBI GeneCards UniProt Show fit	YTH domain containing 1
chr7_-_106285898 Show fit	0.70	ENST00000424768.2 ENST00000681255.1	NAMPT Ensembl NCBI GeneCards UniProt Show fit	nicotinamide phosphoribosyltransferase
chr2_-_9630946 Show fit	0.70	ENST00000446619.1 ENST00000238081.8	YWHAQ Ensembl NCBI GeneCards UniProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr12_+_8914464 Show fit	0.69	ENST00000544916.6	PHC1 Ensembl NCBI GeneCards UniProt Show fit	polyhomeotic homolog 1
chr8_+_30095400 Show fit	0.69	ENST00000321250.13 ENST00000518001.1 ENST00000520682.5 ENST00000442880.6 ENST00000523116.5	LEPROTL1 Ensembl NCBI GeneCards UniProt Show fit	leptin receptor overlapping transcript like 1
chr10_-_14572087 Show fit	0.67	ENST00000482277.5 ENST00000378462.5	FAM107B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member B
chr10_-_97292625 Show fit	0.67	ENST00000466484.1 ENST00000358531.9 ENST00000358308.7	ARHGAP19 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 19
chr8_-_17246590 Show fit	0.67	ENST00000524358.5	CNOT7 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 7
chr1_+_32013848 Show fit	0.65	ENST00000327300.12 ENST00000492989.1	KHDRBS1 Ensembl NCBI GeneCards UniProt Show fit	KH RNA binding domain containing, signal transduction associated 1
chr11_-_117876719 Show fit	0.65	ENST00000529335.6 ENST00000260282.8	FXYD6 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 6
chr12_-_107761113 Show fit	0.64	ENST00000228437.10	PRDM4 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 4
chr19_-_40285277 Show fit	0.63	ENST00000579047.5 ENST00000392038.7	AKT2 Ensembl NCBI GeneCards UniProt Show fit	AKT serine/threonine kinase 2
chr5_+_66828762 Show fit	0.63	ENST00000490016.6 ENST00000403666.5 ENST00000450827.5	MAST4 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated serine/threonine kinase family member 4
chr16_-_15643024 Show fit	0.62	ENST00000540441.6	MARF1 Ensembl NCBI GeneCards UniProt Show fit	meiosis regulator and mRNA stability factor 1
chr12_+_103965798 Show fit	0.61	ENST00000436021.6	TDG Ensembl NCBI GeneCards UniProt Show fit	thymine DNA glycosylase
chr4_+_112231748 Show fit	0.60	ENST00000274000.10 ENST00000309703.10	AP1AR Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 associated regulatory protein
chr7_+_111091006 Show fit	0.60	ENST00000451085.5 ENST00000422987.3 ENST00000421101.1	LRRN3 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat neuronal 3
chrX_-_16863021 Show fit	0.60	ENST00000416035.1	RBBP7 Ensembl NCBI GeneCards UniProt Show fit	RB binding protein 7, chromatin remodeling factor
chr16_+_2770911 Show fit	0.59	ENST00000570539.1	SRRM2 Ensembl NCBI GeneCards UniProt Show fit	serine/arginine repetitive matrix 2
chr20_-_63956382 Show fit	0.58	ENST00000358711.7 ENST00000354216.11	UCKL1 Ensembl NCBI GeneCards UniProt Show fit	uridine-cytidine kinase 1 like 1
chr10_-_14571969 Show fit	0.57	ENST00000488576.5 ENST00000472095.5	FAM107B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member B
chr2_-_37324696 Show fit	0.57	ENST00000443187.1	PRKD3 Ensembl NCBI GeneCards UniProt Show fit	protein kinase D3
chr7_-_106661148 Show fit	0.55	ENST00000523505.3	CCDC71L Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 71 like
chr2_-_127811149 Show fit	0.55	ENST00000322313.9 ENST00000393006.5 ENST00000409658.7 ENST00000436787.5	WDR33 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 33
chr10_-_102419693 Show fit	0.55	ENST00000611678.4	PSD Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing
chr11_-_10808304 Show fit	0.54	ENST00000532082.6	EIF4G2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4 gamma 2
chr3_+_133038366 Show fit	0.54	ENST00000321871.11 ENST00000393130.7 ENST00000514894.5 ENST00000512662.5	TMEM108 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 108
chr19_+_40751179 Show fit	0.53	ENST00000243563.8 ENST00000601393.1	SNRPA Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr12_+_55931070 Show fit	0.52	ENST00000555090.5	DGKA Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase alpha
chr3_-_126056786 Show fit	0.52	ENST00000383598.6	SLC41A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 41 member 3
chr17_-_48613468 Show fit	0.51	ENST00000498634.2	HOXB8 Ensembl NCBI GeneCards UniProt Show fit	homeobox B8
chr1_-_42958836 Show fit	0.51	ENST00000372500.4 ENST00000674765.1 ENST00000460369.3 ENST00000426263.10	SLC2A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 1
chr1_+_35883189 Show fit	0.51	ENST00000674304.1 ENST00000373204.6 ENST00000674426.1	AGO1 Ensembl NCBI GeneCards UniProt Show fit	argonaute RISC component 1
chr12_-_49189053 Show fit	0.51	ENST00000550767.6 ENST00000546918.1 ENST00000679733.1 ENST00000552924.2 ENST00000301071.12	TUBA1A Ensembl NCBI GeneCards UniProt Show fit	tubulin alpha 1a
chr3_-_195542944 Show fit	0.51	ENST00000625807.1	PPP1R2 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 2
chr4_-_156970903 Show fit	0.50	ENST00000422544.2	PDGFC Ensembl NCBI GeneCards UniProt Show fit	platelet derived growth factor C
chr17_-_10518536 Show fit	0.50	ENST00000226207.6	MYH1 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 1
chr9_-_72365198 Show fit	0.50	ENST00000376962.10 ENST00000376960.8	ZFAND5 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 5
chrX_+_106920393 Show fit	0.49	ENST00000336803.2	CLDN2 Ensembl NCBI GeneCards UniProt Show fit	claudin 2
chr17_-_10469558 Show fit	0.49	ENST00000255381.2	MYH4 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr12_-_107760928 Show fit	0.49	ENST00000547188.1	PRDM4 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 4
chr2_-_69961624 Show fit	0.49	ENST00000320256.6	ASPRV1 Ensembl NCBI GeneCards UniProt Show fit	aspartic peptidase retroviral like 1
chr11_-_65614195 Show fit	0.48	ENST00000309100.8 ENST00000529839.1 ENST00000526293.1	MAP3K11 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 11

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	15.1	GO:0032599	B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.7	2.2	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.7	4.2	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.7	8.7	GO:0070543	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6	5.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.6	3.0	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.6	1.8	GO:0035638	patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.6	1.7	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6	2.2	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.5	5.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.4	1.7	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.4	2.1	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.4	2.3	GO:1903232	melanosome assembly(GO:1903232)
0.4	1.5	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.4	10.9	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4	1.1	GO:0002339	B cell selection(GO:0002339)
0.3	1.7	GO:0035574	histone H4-K20 demethylation(GO:0035574)
0.3	1.8	GO:0061181	regulation of chondrocyte development(GO:0061181)
0.3	1.1	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3	1.4	GO:1904693	midbrain morphogenesis(GO:1904693)
0.3	0.8	GO:0021757	caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.3	0.8	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.2	0.7	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2	1.9	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2	1.7	GO:0071484	cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2	2.8	GO:0061042	vascular wound healing(GO:0061042)
0.2	1.1	GO:0035549	positive regulation of interferon-beta secretion(GO:0035549)
0.2	0.4	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2	1.8	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.2	5.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	1.6	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.2	0.8	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.2	0.7	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.2	7.4	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.2	1.8	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	2.9	GO:0038203	TORC2 signaling(GO:0038203)
0.1	1.5	GO:0089700	protein kinase D signaling(GO:0089700)
0.1	0.4	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.1	3.7	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	1.1	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	1.4	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	1.2	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.5	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	0.3	GO:0015881	creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1	0.4	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1	1.2	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1	0.8	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1	0.5	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.6	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	1.8	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.3	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	4.9	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	3.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	0.4	GO:0019521	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1	0.8	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1	1.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.1	0.6	GO:0070370	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1	0.4	GO:0007386	compartment pattern specification(GO:0007386)
0.1	1.3	GO:0007320	insemination(GO:0007320)
0.1	2.7	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	5.1	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.1	0.6	GO:0044211	CTP salvage(GO:0044211)
0.1	1.3	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	0.5	GO:0090625	mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1	1.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.1	0.4	GO:0044334	canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1	1.6	GO:0015671	oxygen transport(GO:0015671)
0.1	1.2	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1	0.3	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.1	4.0	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.2	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
0.0	0.3	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	5.5	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.7	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.5	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0	0.3	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	2.4	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.3	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.8	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.5	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	1.2	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	5.2	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.5	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.5	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.0	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.4	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.3	GO:0097026	dendritic cell dendrite assembly(GO:0097026)
0.0	1.2	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0	0.3	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.0	5.2	GO:0070268	cornification(GO:0070268)
0.0	0.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.2	GO:0018032	protein amidation(GO:0018032)
0.0	1.0	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	1.0	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.6	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	0.7	GO:0051770	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	2.9	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	1.6	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.2	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0	0.6	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	3.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	1.7	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.4	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.8	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.5	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	1.6	GO:0030850	prostate gland development(GO:0030850)
0.0	0.1	GO:0002934	desmosome organization(GO:0002934)
0.0	1.0	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	1.4	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.9	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	1.0	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.2	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.8	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.2	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0	0.5	GO:0006853	carnitine shuttle(GO:0006853)
0.0	1.7	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.8	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.2	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.3	GO:0007379	segment specification(GO:0007379)
0.0	0.8	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	4.9	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.2	GO:0032740	positive regulation of interleukin-17 production(GO:0032740)
0.0	0.1	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.0	0.5	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.2	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	3.0	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.3	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	1.3	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.0	0.3	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	0.6	GO:0007143	female meiotic division(GO:0007143)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	4.0	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.1	3.4	GO:0016590	ACF complex(GO:0016590)
0.6	1.8	GO:0075341	host cell PML body(GO:0075341)
0.6	5.3	GO:0035976	AP1 complex(GO:0035976)
0.5	15.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.5	2.3	GO:0031905	early endosome lumen(GO:0031905)
0.5	3.7	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.5	6.3	GO:0097486	multivesicular body lumen(GO:0097486)
0.4	3.0	GO:0031523	Myb complex(GO:0031523)
0.2	1.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.2	9.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.8	GO:0016035	zeta DNA polymerase complex(GO:0016035)
0.1	3.6	GO:0042588	zymogen granule(GO:0042588)
0.1	0.5	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.1	0.7	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	0.3	GO:0005584	collagen type I trimer(GO:0005584)
0.1	2.7	GO:0045120	pronucleus(GO:0045120)
0.1	2.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	2.9	GO:0031932	TORC2 complex(GO:0031932)
0.1	4.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	1.6	GO:0005833	hemoglobin complex(GO:0005833)
0.1	1.3	GO:0060091	kinocilium(GO:0060091)
0.1	1.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	1.9	GO:0035102	PRC1 complex(GO:0035102)
0.1	2.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	2.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	1.6	GO:0001741	XY body(GO:0001741)
0.1	0.5	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.3	GO:0035061	interchromatin granule(GO:0035061)
0.1	0.8	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.4	GO:0071664	beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1	0.5	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	5.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.6	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.3	GO:0032437	cuticular plate(GO:0032437)
0.0	1.0	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	4.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.5	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.8	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	1.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	1.4	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	4.1	GO:0005882	intermediate filament(GO:0005882)
0.0	0.6	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.3	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	3.2	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	1.1	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	2.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.7	GO:0001917	photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	2.9	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.7	8.7	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.6	1.7	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4	1.1	GO:0045142	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) triplex DNA binding(GO:0045142)
0.3	3.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.3	3.7	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.3	1.7	GO:0035575	histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3	15.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.3	1.1	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.3	1.4	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2	1.8	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.2	5.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	3.9	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2	3.7	GO:0050786	RAGE receptor binding(GO:0050786)
0.2	0.5	GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.2	2.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	3.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.1	0.7	GO:0047280	nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1	5.3	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.3	GO:0005308	creatine transmembrane transporter activity(GO:0005308)
0.1	1.4	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.8	GO:0070411	I-SMAD binding(GO:0070411)
0.1	2.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.5	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	1.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.1	1.5	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.6	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	1.8	GO:0015197	peptide transporter activity(GO:0015197)
0.1	1.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	6.2	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	0.5	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	1.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	2.9	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	1.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	1.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.4	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	1.2	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1	1.6	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0002046	opsin binding(GO:0002046)
0.1	2.2	GO:0031489	myosin V binding(GO:0031489)
0.1	1.8	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.1	1.6	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	1.9	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	1.2	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	0.6	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.3	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	1.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	1.0	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.7	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.8	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.8	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	1.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	3.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	1.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.7	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0	0.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	1.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.4	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	1.4	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	1.2	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.5	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	5.8	GO:0017124	SH3 domain binding(GO:0017124)
0.0	1.0	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.6	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.5	GO:0035198	miRNA binding(GO:0035198)
0.0	2.0	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	5.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	7.6	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	1.1	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	3.4	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.0	GO:0042169	SH2 domain binding(GO:0042169)
0.0	4.9	GO:0008201	heparin binding(GO:0008201)
0.0	0.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	2.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.5	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.0	0.6	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	6.6	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	1.8	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	2.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	3.9	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	3.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	7.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	7.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	3.7	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	6.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	3.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	3.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	5.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	4.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.0	PID MYC PATHWAY	C-MYC pathway
0.0	0.8	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.8	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.3	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.6	PID FOXO PATHWAY	FoxO family signaling
0.0	0.8	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	4.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	5.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.7	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	8.7	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.1	1.4	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	3.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	1.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	2.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	10.5	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	1.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	1.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	1.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	1.4	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	3.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	5.2	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	3.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.7	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.7	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	2.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing

Results for TCF7L1

Z-value: 1.31

Motif logo

Transcription factors associated with TCF7L1

Activity-expression correlation:

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: