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Illumina Body Map 2 (GSE30611)

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Results for TEAD3_TEAD1

Z-value: 5.35

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Transcription factors associated with TEAD3_TEAD1

Gene Symbol Gene ID Gene Info
ENSG00000007866.22 TEA domain transcription factor 3
ENSG00000187079.20 TEA domain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD1hg38_v1_chr11_+_12674397_126744420.914.2e-13Click!
TEAD3hg38_v1_chr6_-_35497042_354971170.803.7e-08Click!

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_131951364 58.81 ENST00000367976.4
cellular communication network factor 2
chr1_-_16018005 38.16 ENST00000406363.2
ENST00000411503.5
ENST00000311890.14
ENST00000487046.1
heat shock protein family B (small) member 7
chr3_-_119660580 34.50 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chr10_-_88952763 30.75 ENST00000224784.10
actin alpha 2, smooth muscle
chr1_-_214551556 30.60 ENST00000366956.10
protein tyrosine phosphatase non-receptor type 14
chr14_-_23435652 30.54 ENST00000355349.4
myosin heavy chain 7
chr17_-_42423246 26.55 ENST00000357037.6
caveolae associated protein 1
chr1_+_85580751 26.18 ENST00000451137.7
cellular communication network factor 1
chr1_-_16017825 26.09 ENST00000463576.5
heat shock protein family B (small) member 7
chr7_+_116525524 24.47 ENST00000405348.6
caveolin 1
chr9_+_70043840 22.72 ENST00000377182.5
MAM domain containing 2
chr7_+_116525028 22.61 ENST00000341049.7
caveolin 1
chr7_+_116524984 21.57 ENST00000614113.5
ENST00000393470.1
caveolin 1
chr15_+_63042632 20.61 ENST00000288398.10
ENST00000358278.7
ENST00000610733.1
ENST00000403994.9
ENST00000357980.9
ENST00000559556.5
ENST00000267996.11
ENST00000559397.6
ENST00000561266.6
ENST00000560970.6
tropomyosin 1
chr11_+_102110437 19.24 ENST00000282441.10
ENST00000526343.5
ENST00000537274.5
ENST00000345877.6
ENST00000615667.4
Yes1 associated transcriptional regulator
chr3_-_134374439 18.10 ENST00000513145.1
ENST00000249883.10
ENST00000422605.6
angiomotin like 2
chr3_-_112641292 17.83 ENST00000439685.6
coiled-coil domain containing 80
chr6_+_118548289 17.34 ENST00000357525.6
phospholamban
chr8_-_81483226 17.29 ENST00000256104.5
fatty acid binding protein 4
chr12_-_7092422 16.93 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr11_+_67056805 16.88 ENST00000308831.7
ras homolog family member D
chr5_-_139462701 16.69 ENST00000618155.3
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr14_-_23408265 16.43 ENST00000405093.9
myosin heavy chain 6
chr4_-_185812209 16.20 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr15_+_96325935 15.89 ENST00000421109.6
nuclear receptor subfamily 2 group F member 2
chr16_+_30375820 15.51 ENST00000566955.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr10_+_122112957 15.37 ENST00000369001.5
transforming acidic coiled-coil containing protein 2
chr6_+_30882914 15.20 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
discoidin domain receptor tyrosine kinase 1
chr1_-_229434086 15.14 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
actin alpha 1, skeletal muscle
chr3_-_112641128 14.97 ENST00000206423.8
coiled-coil domain containing 80
chr1_+_77888645 14.74 ENST00000440324.5
nexilin F-actin binding protein
chr7_+_134779625 14.61 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr10_+_24208774 14.21 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr7_+_134779663 14.12 ENST00000361901.6
caldesmon 1
chr11_-_111910830 14.09 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr1_+_183186238 14.03 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr1_-_1358524 14.00 ENST00000445648.5
ENST00000309212.11
matrix remodeling associated 8
chr3_-_149657996 13.92 ENST00000360632.8
ENST00000467467.5
ENST00000460517.1
WW domain containing transcription regulator 1
chr12_+_27524151 13.91 ENST00000545334.5
ENST00000540114.5
ENST00000537927.5
ENST00000228425.11
ENST00000318304.12
ENST00000535047.5
ENST00000542629.5
PPFIA binding protein 1
chr12_-_95790755 13.89 ENST00000343702.9
ENST00000344911.8
netrin 4
chr4_-_151227881 13.86 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr11_-_111910888 13.73 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr14_-_88554898 13.54 ENST00000556564.6
protein tyrosine phosphatase non-receptor type 21
chr16_-_72620 13.46 ENST00000262316.10
rhomboid 5 homolog 1
chr1_+_77888612 13.44 ENST00000334785.12
nexilin F-actin binding protein
chr1_-_201469151 13.40 ENST00000367311.5
ENST00000367309.1
pleckstrin homology like domain family A member 3
chr1_+_77888490 13.36 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr12_-_7092484 13.31 ENST00000541042.5
ENST00000540242.2
complement C1r
chr16_+_30374794 13.15 ENST00000322861.12
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_+_102110692 13.13 ENST00000629586.2
ENST00000531439.5
Yes1 associated transcriptional regulator
chr11_-_111910790 12.90 ENST00000533280.6
crystallin alpha B
chr1_-_26067622 12.82 ENST00000374272.4
tripartite motif containing 63
chr1_-_94925759 12.35 ENST00000415017.1
ENST00000545882.5
calponin 3
chr10_+_24209129 12.18 ENST00000376454.8
ENST00000635504.1
KIAA1217
chr1_-_201377652 12.12 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
troponin T2, cardiac type
chr12_+_2959296 12.07 ENST00000358409.7
ENST00000359864.8
ENST00000540314.2
ENST00000536826.2
TEA domain transcription factor 4
chr11_+_67056875 11.83 ENST00000532559.1
ras homolog family member D
chr4_+_183099244 11.66 ENST00000403733.8
WW and C2 domain containing 2
chr12_-_110920568 11.46 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr10_-_17617235 11.39 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr12_-_95791135 11.29 ENST00000538383.5
netrin 4
chr11_-_76669985 11.27 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32
chr7_+_128830399 11.26 ENST00000325888.13
ENST00000346177.6
filamin C
chr15_+_62561361 11.01 ENST00000561311.5
talin 2
chr12_-_7092529 10.98 ENST00000540610.5
complement C1r
chr5_+_55160161 10.88 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr12_-_8662808 10.51 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr1_-_58577244 10.17 ENST00000371225.4
tumor associated calcium signal transducer 2
chr6_-_35497042 10.07 ENST00000639578.3
ENST00000338863.13
TEA domain transcription factor 3
chr4_-_186723776 10.00 ENST00000614102.4
ENST00000441802.7
FAT atypical cadherin 1
chr14_-_22982544 9.99 ENST00000262713.7
ajuba LIM protein
chr17_+_4997901 9.97 ENST00000320785.10
ENST00000574165.1
kinesin family member 1C
chr19_+_15107369 9.89 ENST00000342784.7
ENST00000597977.5
ENST00000600440.5
synapse defective Rho GTPase homolog 1
chr1_-_201946469 9.88 ENST00000367288.5
leiomodin 1
chr2_+_27282419 9.71 ENST00000380075.7
ENST00000296098.4
tripartite motif containing 54
chr7_+_134745460 9.71 ENST00000436461.6
caldesmon 1
chr4_+_168631597 9.61 ENST00000504519.5
ENST00000512127.5
palladin, cytoskeletal associated protein
chr1_-_93585071 9.57 ENST00000539242.5
BCAR3 adaptor protein, NSP family member
chr11_-_8810635 9.56 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr6_-_42142604 9.45 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr4_-_185811738 9.19 ENST00000451958.5
ENST00000439914.5
ENST00000428330.5
ENST00000429056.5
sorbin and SH3 domain containing 2
chr17_-_41521719 9.17 ENST00000393976.6
keratin 15
chr17_+_7855055 9.10 ENST00000574668.1
ENST00000301599.7
transmembrane protein 88
chr5_-_38595396 9.08 ENST00000263409.8
LIF receptor subunit alpha
chr1_-_201946571 9.01 ENST00000616739.1
leiomodin 1
chr17_-_29622893 8.99 ENST00000345068.9
ENST00000584602.1
ENST00000388767.8
ENST00000580212.6
coronin 6
chr13_-_21061492 8.75 ENST00000382592.5
large tumor suppressor kinase 2
chr16_+_28878480 8.68 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr22_+_41560973 8.63 ENST00000306149.12
cold shock domain containing C2
chr16_+_28878382 8.60 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr1_+_61952036 8.55 ENST00000646453.1
ENST00000635137.1
PATJ crumbs cell polarity complex component
chr2_+_102142738 8.48 ENST00000410023.6
ENST00000409288.5
interleukin 1 receptor type 1
chr8_+_69466617 8.42 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
sulfatase 1
chr16_+_30896606 8.41 ENST00000279804.3
ENST00000395019.3
cardiotrophin 1
chr10_+_68109433 8.32 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr18_+_34593312 8.23 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chrX_-_15384402 8.11 ENST00000297904.4
vascular endothelial growth factor D
chr20_+_36541511 8.04 ENST00000279022.7
myosin light chain 9
chr11_+_114296347 8.04 ENST00000299964.4
nicotinamide N-methyltransferase
chr19_+_44905785 7.94 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr2_-_210315160 7.85 ENST00000352451.4
myosin light chain 1
chr7_+_94394886 7.81 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr12_-_8662619 7.79 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr11_-_8810974 7.71 ENST00000530438.5
DENN domain containing 2B
chr20_+_36541484 7.71 ENST00000346786.2
myosin light chain 9
chr6_-_75206044 7.70 ENST00000322507.13
collagen type XII alpha 1 chain
chr4_+_41612892 7.68 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr5_+_145936554 7.65 ENST00000359120.9
SH3 domain containing ring finger 2
chr8_+_1823967 7.54 ENST00000520359.5
ENST00000518288.5
Rho guanine nucleotide exchange factor 10
chr14_+_63204436 7.51 ENST00000316754.8
ras homolog family member J
chr2_-_178804623 7.48 ENST00000359218.10
ENST00000342175.11
titin
chr1_-_161309961 7.46 ENST00000533357.5
ENST00000672602.2
ENST00000526189.3
myelin protein zero
chr2_+_106065678 7.45 ENST00000238044.8
ENST00000437659.1
ECRG4 augurin precursor
chr22_+_25742141 7.33 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
myosin XVIIIB
chr2_+_169509693 7.20 ENST00000284669.2
kelch like family member 41
chr7_-_138755892 7.15 ENST00000644341.1
ENST00000478480.2
ATPase H+ transporting V0 subunit a4
chr3_-_149333619 7.13 ENST00000296059.7
transmembrane 4 L six family member 18
chr19_+_40627033 7.11 ENST00000599225.1
ENST00000598166.2
latent transforming growth factor beta binding protein 4
chr6_+_133889105 7.09 ENST00000367882.5
transcription factor 21
chr10_+_110644306 7.02 ENST00000369519.4
RNA binding motif protein 20
chr3_+_9902808 7.01 ENST00000383814.8
ENST00000454190.6
ENST00000454992.1
interleukin 17 receptor E
chr4_+_109912877 6.89 ENST00000265171.10
ENST00000509793.5
ENST00000652245.1
epidermal growth factor
chr10_-_20897288 6.87 ENST00000377122.9
nebulette
chr8_+_1823918 6.82 ENST00000349830.8
Rho guanine nucleotide exchange factor 10
chr2_+_173075435 6.81 ENST00000539448.5
mitogen-activated protein kinase kinase kinase 20
chr4_-_185956348 6.80 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr4_+_25655822 6.79 ENST00000504570.5
ENST00000382051.8
solute carrier family 34 member 2
chr8_-_38467701 6.77 ENST00000425967.8
ENST00000533668.5
ENST00000413133.6
ENST00000397108.8
ENST00000526742.5
ENST00000525001.5
ENST00000529552.5
ENST00000397113.6
fibroblast growth factor receptor 1
chr17_+_39700046 6.72 ENST00000269571.10
erb-b2 receptor tyrosine kinase 2
chr19_+_50432885 6.69 ENST00000357701.6
myosin binding protein C2
chr11_-_64246190 6.67 ENST00000392210.6
protein phosphatase 1 regulatory inhibitor subunit 14B
chr12_-_8662881 6.67 ENST00000433590.6
microfibril associated protein 5
chr7_+_100867379 6.66 ENST00000200457.9
ENST00000619988.4
thyroid hormone receptor interactor 6
chr1_+_61082553 6.56 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr4_-_185810894 6.55 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr2_-_217905445 6.54 ENST00000413554.5
tensin 1
chr1_+_61952283 6.52 ENST00000307297.8
PATJ crumbs cell polarity complex component
chr3_-_149333407 6.51 ENST00000470080.5
transmembrane 4 L six family member 18
chrX_+_100644183 6.50 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr12_-_104050112 6.44 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
glycosyltransferase 8 domain containing 2
chr10_-_90921079 6.41 ENST00000371697.4
ankyrin repeat domain 1
chr7_+_30921430 6.39 ENST00000409899.5
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr12_-_79690957 6.37 ENST00000328827.9
pro-apoptotic WT1 regulator
chr19_+_40611863 6.36 ENST00000601032.5
latent transforming growth factor beta binding protein 4
chr20_-_64049631 6.33 ENST00000340356.9
SRY-box transcription factor 18
chr19_+_50188180 6.27 ENST00000598205.5
myosin heavy chain 14
chr1_+_113979391 6.26 ENST00000393300.6
ENST00000369551.5
olfactomedin like 3
chr1_-_16156059 6.23 ENST00000358432.8
EPH receptor A2
chr12_+_2959870 6.22 ENST00000397122.6
TEA domain transcription factor 4
chr6_+_19837362 6.20 ENST00000378700.8
inhibitor of DNA binding 4, HLH protein
chr1_+_164559173 6.20 ENST00000420696.7
PBX homeobox 1
chr3_+_9902619 6.19 ENST00000421412.5
interleukin 17 receptor E
chr11_-_64245816 6.12 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr16_+_2033264 6.10 ENST00000565855.5
ENST00000566198.1
SLC9A3 regulator 2
chr12_-_110920710 6.06 ENST00000546404.1
myosin light chain 2
chr2_+_173075714 6.05 ENST00000409176.6
ENST00000338983.7
ENST00000375213.8
mitogen-activated protein kinase kinase kinase 20
chr3_-_52835011 6.04 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr17_+_39699960 6.02 ENST00000445658.6
erb-b2 receptor tyrosine kinase 2
chr8_-_107497909 5.94 ENST00000517746.6
angiopoietin 1
chr7_+_32979445 5.94 ENST00000418354.5
ENST00000490776.3
FKBP prolyl isomerase 9
chr5_-_59586393 5.93 ENST00000505453.1
ENST00000360047.9
phosphodiesterase 4D
chr1_+_19640520 5.92 ENST00000428975.5
NBL1, DAN family BMP antagonist
chr17_+_39700000 5.92 ENST00000584450.5
erb-b2 receptor tyrosine kinase 2
chr4_-_185811965 5.91 ENST00000419063.5
sorbin and SH3 domain containing 2
chr3_-_52834901 5.91 ENST00000486659.5
musculoskeletal, embryonic nuclear protein 1
chr11_+_46277648 5.89 ENST00000621158.5
cAMP responsive element binding protein 3 like 1
chr1_-_24112125 5.86 ENST00000374434.4
myomesin 3
chr6_-_75205843 5.79 ENST00000345356.10
collagen type XII alpha 1 chain
chr8_-_107498041 5.76 ENST00000297450.7
angiopoietin 1
chr17_+_72121012 5.75 ENST00000245479.3
SRY-box transcription factor 9
chr11_-_47449129 5.74 ENST00000298854.7
ENST00000524487.5
ENST00000529341.1
ENST00000352508.7
receptor associated protein of the synapse
chr9_+_99821846 5.71 ENST00000338488.8
ENST00000618101.4
nuclear receptor subfamily 4 group A member 3
chr21_-_38661694 5.69 ENST00000417133.6
ENST00000398910.5
ENST00000442448.5
ENST00000429727.6
ETS transcription factor ERG
chr5_-_39424966 5.66 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr2_-_215393126 5.63 ENST00000456923.5
fibronectin 1
chr9_-_14321948 5.62 ENST00000635877.1
ENST00000636432.1
ENST00000646622.1
nuclear factor I B
chr16_+_23182737 5.60 ENST00000300061.3
sodium channel epithelial 1 subunit gamma
chr10_+_122163672 5.55 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chr11_+_7485492 5.52 ENST00000534244.1
ENST00000329293.4
olfactomedin like 1
chr10_+_80131660 5.52 ENST00000372270.6
placenta associated 9
chr2_+_227164607 5.49 ENST00000396578.8
collagen type IV alpha 3 chain
chr2_-_189179754 5.49 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr9_-_13175824 5.47 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr16_-_67968553 5.44 ENST00000576616.5
ENST00000572037.5
ENST00000316341.8
ENST00000422611.6
solute carrier family 12 member 4
chr19_-_45769204 5.43 ENST00000317578.7
SIX homeobox 5
chr3_-_52452828 5.43 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr19_-_54473208 5.42 ENST00000301200.3
CDC42 effector protein 5
chr17_-_69060906 5.39 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ATP binding cassette subfamily A member 9
chr8_-_123653794 5.37 ENST00000684634.1
kelch like family member 38
chr1_+_26177482 5.37 ENST00000361530.11
ENST00000374253.9
connector enhancer of kinase suppressor of Ras 1
chr1_-_153613095 5.37 ENST00000368706.9
S100 calcium binding protein A16
chr1_+_113979460 5.37 ENST00000320334.5
olfactomedin like 3
chr12_+_52051402 5.33 ENST00000243050.5
ENST00000550763.1
ENST00000394825.6
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4 group A member 1
chr6_-_75205822 5.29 ENST00000483888.6
collagen type XII alpha 1 chain
chr15_+_74174403 5.26 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine rich repeat
chr1_+_156106698 5.26 ENST00000675667.1
lamin A/C
chr9_-_14307928 5.24 ENST00000637640.1
ENST00000493697.1
ENST00000636057.1
nuclear factor I B
chr12_-_8662703 5.22 ENST00000535336.5
microfibril associated protein 5
chr7_+_107660819 5.22 ENST00000644269.2
solute carrier family 26 member 4
chr17_-_75515509 5.21 ENST00000321617.8
CASK interacting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
17.2 68.6 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
12.0 47.8 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
7.6 45.9 GO:0090131 mesenchyme migration(GO:0090131)
5.8 17.3 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
4.4 17.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
4.4 8.8 GO:0048769 sarcomerogenesis(GO:0048769)
4.1 20.6 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
4.0 15.9 GO:0009956 radial pattern formation(GO:0009956)
3.9 11.7 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
3.6 25.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
3.4 20.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
3.1 18.7 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
3.0 73.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
2.9 8.8 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
2.9 20.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
2.9 5.8 GO:0072190 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
2.6 7.9 GO:2000646 lipid transport involved in lipid storage(GO:0010877) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
2.5 14.9 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.4 46.3 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
2.4 7.1 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
2.3 9.1 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
2.3 6.8 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
2.2 8.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.2 10.8 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
2.1 12.8 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.1 6.4 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
2.1 6.2 GO:1901491 axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
2.1 14.5 GO:0048014 Tie signaling pathway(GO:0048014)
1.9 18.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.9 5.6 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
1.8 27.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.8 8.9 GO:0035026 leading edge cell differentiation(GO:0035026)
1.8 40.7 GO:0007021 tubulin complex assembly(GO:0007021)
1.7 19.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.7 10.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.7 6.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.7 36.9 GO:0001946 lymphangiogenesis(GO:0001946)
1.6 8.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.6 17.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.6 23.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.6 6.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
1.6 6.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.5 5.9 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
1.4 8.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.4 5.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.4 62.5 GO:0035329 hippo signaling(GO:0035329)
1.3 6.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
1.3 3.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.2 3.7 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
1.2 13.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
1.2 1.2 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
1.2 3.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.1 17.3 GO:0071285 cellular response to lithium ion(GO:0071285)
1.1 1.1 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
1.0 7.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
1.0 5.2 GO:0042360 vitamin E metabolic process(GO:0042360)
1.0 11.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.0 56.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.0 10.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.9 5.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.9 6.6 GO:0051012 microtubule sliding(GO:0051012)
0.9 18.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.9 6.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.9 2.7 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.9 5.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.9 3.4 GO:0022012 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.9 5.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.8 10.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8 19.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.8 3.9 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.8 5.4 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.7 27.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.7 11.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.7 4.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7 4.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.7 4.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.7 4.8 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.6 5.7 GO:0072093 metanephric renal vesicle formation(GO:0072093)
0.6 7.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.6 4.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.6 7.4 GO:0015705 iodide transport(GO:0015705)
0.6 12.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.6 30.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.6 10.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.6 5.2 GO:0002159 desmosome assembly(GO:0002159)
0.6 4.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.6 28.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.6 3.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.6 5.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.6 11.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.5 9.3 GO:0043589 skin morphogenesis(GO:0043589)
0.5 1.6 GO:0006481 C-terminal protein methylation(GO:0006481)
0.5 2.2 GO:0035853 chromosome passenger complex localization to spindle midzone(GO:0035853)
0.5 3.2 GO:0008218 bioluminescence(GO:0008218)
0.5 18.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.5 3.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.5 1.6 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.5 3.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.5 10.2 GO:0072189 ureter development(GO:0072189)
0.5 4.0 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.5 14.0 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.5 11.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.5 11.4 GO:0030497 fatty acid elongation(GO:0030497)
0.5 5.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.5 7.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.5 13.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.5 7.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.5 14.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.5 3.3 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.5 0.5 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627) positive regulation of miRNA metabolic process(GO:2000630)
0.5 5.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.4 5.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 1.3 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.4 6.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.4 2.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.4 3.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.4 1.3 GO:0042245 RNA repair(GO:0042245)
0.4 7.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.4 1.7 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.4 3.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4 2.9 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.4 3.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.4 3.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.4 4.9 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.4 1.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 1.6 GO:1903412 response to bile acid(GO:1903412)
0.4 7.0 GO:1901626 regulation of postsynaptic membrane organization(GO:1901626)
0.4 6.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.4 1.5 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.4 3.0 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.4 55.7 GO:0008016 regulation of heart contraction(GO:0008016)
0.4 2.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.4 1.4 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4 9.6 GO:0003334 keratinocyte development(GO:0003334)
0.3 0.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 3.7 GO:0010040 response to iron(II) ion(GO:0010040)
0.3 1.3 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 2.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.3 1.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 0.6 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.3 8.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3 6.4 GO:0035994 response to muscle stretch(GO:0035994)
0.3 17.2 GO:0030199 collagen fibril organization(GO:0030199)
0.3 20.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.3 16.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 1.8 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.3 2.4 GO:0008354 germ cell migration(GO:0008354) regulation of collagen catabolic process(GO:0010710)
0.3 2.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 44.4 GO:0030449 regulation of complement activation(GO:0030449)
0.3 4.1 GO:0051451 myoblast migration(GO:0051451)
0.3 2.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.3 3.7 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3 13.5 GO:0030252 growth hormone secretion(GO:0030252)
0.3 1.1 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 6.6 GO:0098743 cell aggregation(GO:0098743)
0.3 2.2 GO:0060005 vestibular reflex(GO:0060005)
0.3 5.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 8.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 5.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.3 2.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.2 2.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.2 1.2 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343) cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 3.8 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 4.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 2.8 GO:0060056 mammary gland involution(GO:0060056)
0.2 32.5 GO:0002027 regulation of heart rate(GO:0002027)
0.2 5.1 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 96.3 GO:0006936 muscle contraction(GO:0006936)
0.2 1.8 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.2 6.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 11.0 GO:0048747 muscle fiber development(GO:0048747)
0.2 3.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 16.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 1.5 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.2 5.6 GO:0055078 sodium ion homeostasis(GO:0055078)
0.2 2.3 GO:0009644 response to high light intensity(GO:0009644)
0.2 2.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 1.0 GO:0061107 seminal vesicle development(GO:0061107)
0.2 0.8 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 2.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 12.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.2 4.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 0.6 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 2.7 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 28.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.2 6.5 GO:0015695 organic cation transport(GO:0015695)
0.2 0.5 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.2 3.6 GO:0051764 actin crosslink formation(GO:0051764)
0.2 3.1 GO:0045475 locomotor rhythm(GO:0045475)
0.2 1.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 2.0 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 2.8 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.2 1.1 GO:0001945 lymph vessel development(GO:0001945)
0.2 1.6 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 0.6 GO:0007538 primary sex determination(GO:0007538)
0.2 3.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 1.2 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 7.9 GO:0010761 fibroblast migration(GO:0010761)
0.1 13.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 3.4 GO:0007097 nuclear migration(GO:0007097)
0.1 3.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 1.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 3.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 4.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 0.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 5.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 7.0 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 3.5 GO:0006825 copper ion transport(GO:0006825)
0.1 3.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 6.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 1.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 4.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 16.6 GO:0021987 cerebral cortex development(GO:0021987)
0.1 1.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 1.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.7 GO:0051382 kinetochore assembly(GO:0051382)
0.1 10.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 4.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 3.4 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.1 12.9 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 2.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 4.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.3 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.9 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 2.1 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 1.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 1.0 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.0 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 3.9 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 1.1 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.3 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 9.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.8 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 2.9 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 2.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 2.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 5.7 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0071316 olfactory nerve development(GO:0021553) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) cellular response to nicotine(GO:0071316)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 2.3 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 1.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.0 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.4 GO:1903363 negative regulation of cellular protein catabolic process(GO:1903363)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.4 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
4.4 30.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
4.2 72.1 GO:0097512 cardiac myofibril(GO:0097512)
3.8 18.8 GO:0005595 collagen type XII trimer(GO:0005595)
3.4 67.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
3.3 9.8 GO:0005900 oncostatin-M receptor complex(GO:0005900)
3.1 9.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
2.7 5.4 GO:1990584 cardiac Troponin complex(GO:1990584)
2.6 7.8 GO:0005584 collagen type I trimer(GO:0005584)
2.6 119.1 GO:0005859 muscle myosin complex(GO:0005859)
2.3 35.1 GO:0030478 actin cap(GO:0030478)
2.1 6.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
2.0 7.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.7 8.5 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.7 5.0 GO:0070195 growth hormone receptor complex(GO:0070195)
1.5 5.8 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.4 5.5 GO:0005588 collagen type V trimer(GO:0005588)
1.2 54.6 GO:0036379 myofilament(GO:0036379)
1.2 6.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
1.2 17.9 GO:0043256 laminin complex(GO:0043256)
1.1 42.1 GO:0005614 interstitial matrix(GO:0005614)
1.1 8.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.1 28.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.8 5.7 GO:0097513 myosin II filament(GO:0097513)
0.8 64.4 GO:0016235 aggresome(GO:0016235)
0.7 7.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7 11.7 GO:0016013 syntrophin complex(GO:0016013)
0.6 19.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.6 5.7 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.6 33.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.6 161.5 GO:0030018 Z disc(GO:0030018)
0.5 9.8 GO:0030056 hemidesmosome(GO:0030056)
0.5 14.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 3.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 5.3 GO:0005638 lamin filament(GO:0005638)
0.5 24.7 GO:0009925 basal plasma membrane(GO:0009925)
0.5 8.9 GO:0031672 A band(GO:0031672)
0.4 7.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.4 3.5 GO:0005579 membrane attack complex(GO:0005579)
0.4 5.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.4 1.1 GO:0097135 X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135)
0.4 4.8 GO:0016600 flotillin complex(GO:0016600)
0.3 3.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 1.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 4.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 6.4 GO:0031674 I band(GO:0031674)
0.3 3.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 6.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 2.0 GO:0071942 XPC complex(GO:0071942)
0.3 5.6 GO:0005605 basal lamina(GO:0005605)
0.3 5.6 GO:0034706 sodium channel complex(GO:0034706)
0.3 6.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.3 3.5 GO:0044754 autolysosome(GO:0044754)
0.3 10.8 GO:0042629 mast cell granule(GO:0042629)
0.3 1.0 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.2 1.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 22.8 GO:0005604 basement membrane(GO:0005604)
0.2 26.4 GO:0005901 caveola(GO:0005901)
0.2 4.2 GO:0045180 basal cortex(GO:0045180)
0.2 44.8 GO:0042383 sarcolemma(GO:0042383)
0.2 2.2 GO:0005827 polar microtubule(GO:0005827)
0.2 45.1 GO:0072562 blood microparticle(GO:0072562)
0.2 3.4 GO:0005869 dynactin complex(GO:0005869)
0.2 105.6 GO:0016324 apical plasma membrane(GO:0016324)
0.2 0.6 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 16.6 GO:0005902 microvillus(GO:0005902)
0.2 3.0 GO:0034709 methylosome(GO:0034709)
0.2 4.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 3.6 GO:0031941 filamentous actin(GO:0031941)
0.2 16.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 5.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 18.7 GO:0005811 lipid particle(GO:0005811)
0.1 84.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 14.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.5 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 17.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 8.0 GO:0005771 multivesicular body(GO:0005771)
0.1 3.4 GO:0016459 myosin complex(GO:0016459)
0.1 2.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 2.9 GO:0010369 chromocenter(GO:0010369)
0.1 26.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 7.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 5.6 GO:0005903 brush border(GO:0005903)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 6.0 GO:0005884 actin filament(GO:0005884)
0.1 6.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 10.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 6.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 24.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 10.5 GO:0016605 PML body(GO:0016605)
0.1 3.5 GO:0042641 actomyosin(GO:0042641)
0.1 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.3 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 8.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.8 GO:0071004 U1 snRNP(GO:0005685) U2-type prespliceosome(GO:0071004)
0.0 2.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 4.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 13.3 GO:0005769 early endosome(GO:0005769)
0.0 2.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 14.8 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 1.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 26.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 6.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
17.2 68.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
6.6 26.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
3.8 11.4 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
3.1 18.9 GO:0004924 oncostatin-M receptor activity(GO:0004924)
2.9 17.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.8 8.5 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
2.8 25.2 GO:0043237 laminin-1 binding(GO:0043237)
2.5 76.3 GO:0005523 tropomyosin binding(GO:0005523)
2.2 67.8 GO:0031005 filamin binding(GO:0031005)
2.1 6.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
2.1 6.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
2.0 16.3 GO:0017018 myosin phosphatase activity(GO:0017018)
1.9 18.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.8 43.4 GO:0032036 myosin heavy chain binding(GO:0032036)
1.6 7.9 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
1.5 196.1 GO:0008307 structural constituent of muscle(GO:0008307)
1.5 13.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.5 5.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.4 36.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.3 7.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.3 12.8 GO:0031432 titin binding(GO:0031432)
1.2 7.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.2 4.9 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
1.2 8.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
1.2 38.4 GO:0005212 structural constituent of eye lens(GO:0005212)
1.2 17.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.2 18.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
1.1 10.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.0 18.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0 4.0 GO:0004967 glucagon receptor activity(GO:0004967)
1.0 4.0 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.9 8.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.9 5.3 GO:0031013 troponin I binding(GO:0031013)
0.9 38.2 GO:0070064 proline-rich region binding(GO:0070064)
0.8 10.7 GO:0038132 neuregulin binding(GO:0038132)
0.8 37.2 GO:0001968 fibronectin binding(GO:0001968)
0.8 8.3 GO:0019534 toxin transporter activity(GO:0019534)
0.7 2.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.7 3.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 2.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.7 13.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.6 9.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.6 7.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 13.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.6 18.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.6 8.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.6 3.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 1.6 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.5 2.1 GO:1990254 keratin filament binding(GO:1990254)
0.5 1.6 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.5 6.7 GO:0036122 BMP binding(GO:0036122)
0.5 7.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 7.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 13.8 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.5 16.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 4.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 15.1 GO:0030506 ankyrin binding(GO:0030506)
0.4 6.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.4 9.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 1.5 GO:0010736 serum response element binding(GO:0010736)
0.4 3.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 3.0 GO:0044020 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.4 10.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.4 16.9 GO:0001972 retinoic acid binding(GO:0001972)
0.4 4.7 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 9.5 GO:0043495 protein anchor(GO:0043495)
0.3 1.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.3 11.4 GO:0035497 cAMP response element binding(GO:0035497)
0.3 12.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 1.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 6.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 9.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 9.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 1.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.3 1.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3 38.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 34.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 4.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 3.5 GO:0004969 histamine receptor activity(GO:0004969)
0.3 7.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 4.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 3.7 GO:0070700 BMP receptor binding(GO:0070700)
0.3 8.7 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 7.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 20.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 7.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 4.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 2.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 1.6 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 5.1 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 4.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 31.8 GO:0019838 growth factor binding(GO:0019838)
0.2 14.1 GO:0005504 fatty acid binding(GO:0005504)
0.2 9.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 8.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.0 GO:0034711 inhibin binding(GO:0034711)
0.2 3.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 5.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 1.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 24.5 GO:0030165 PDZ domain binding(GO:0030165)
0.2 14.4 GO:0019894 kinesin binding(GO:0019894)
0.2 3.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 1.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.2 2.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 10.0 GO:0043531 ADP binding(GO:0043531)
0.2 1.7 GO:0004849 uridine kinase activity(GO:0004849)
0.2 3.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 4.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 4.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 31.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 3.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 58.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.4 GO:0039706 co-receptor binding(GO:0039706)
0.1 3.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 2.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.7 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 28.8 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.1 15.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 11.6 GO:0032947 protein complex scaffold(GO:0032947)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 44.6 GO:0003924 GTPase activity(GO:0003924)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 2.8 GO:0005112 Notch binding(GO:0005112)
0.1 4.2 GO:0030332 cyclin binding(GO:0030332)
0.1 3.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 17.1 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 10.7 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 6.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 22.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 22.8 GO:0008017 microtubule binding(GO:0008017)
0.1 6.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.4 GO:0030507 spectrin binding(GO:0030507)
0.1 1.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 4.9 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 2.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 9.5 GO:0045296 cadherin binding(GO:0045296)
0.0 2.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 4.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 4.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 2.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.3 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 1.2 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 10.5 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 3.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.9 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 6.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.3 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 74.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
1.2 27.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.8 17.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.5 15.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.5 23.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 38.6 NABA COLLAGENS Genes encoding collagen proteins
0.4 31.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 27.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 39.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 31.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.4 6.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 2.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 4.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 3.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.3 17.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 37.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 40.2 PID SHP2 PATHWAY SHP2 signaling
0.3 5.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 33.9 PID NOTCH PATHWAY Notch signaling pathway
0.3 4.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 11.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 8.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 22.8 PID AP1 PATHWAY AP-1 transcription factor network
0.2 17.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 31.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 11.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 5.4 PID IL3 PATHWAY IL3-mediated signaling events
0.1 12.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 13.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 5.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 8.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 4.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 3.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 8.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 8.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 19.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.7 PID ARF 3PATHWAY Arf1 pathway
0.1 1.3 PID INSULIN PATHWAY Insulin Pathway
0.1 3.5 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.8 PID FGF PATHWAY FGF signaling pathway
0.0 3.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.3 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 3.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 11.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 9.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 89.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
2.1 84.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
2.0 127.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
1.5 86.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.8 33.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.7 28.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.6 26.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.5 18.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 21.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.5 13.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 10.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.5 6.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.4 37.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.4 1.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.4 6.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 2.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 9.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 3.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 29.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 11.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 5.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 32.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 8.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 8.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 3.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 13.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 6.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 6.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 16.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 25.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 4.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 9.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 9.1 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 2.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 7.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 6.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 5.5 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 3.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.9 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 4.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 4.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation