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Illumina Body Map 2 (GSE30611)

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Results for TFAP2B

Z-value: 1.00

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
TFAP2B
ENSG00000008196.13 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Bhg38_v1_chr6_+_50818701_508187230.029.2e-01Click!

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_63700100 5.89 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIMD2
LIM domain containing 2
chr4_+_1721470 4.38 ENST00000612220.5
ENST00000313288.9
TACC3
transforming acidic coiled-coil containing protein 3
chr4_-_83109843 3.35 ENST00000411416.6
PLAC8
placenta associated 8
chr5_-_157575767 3.22 ENST00000257527.9
ADAM19
ADAM metallopeptidase domain 19
chr16_-_88706353 3.18 ENST00000567844.1
ENST00000312838.9
RNF166
ring finger protein 166
chr1_+_209756032 3.10 ENST00000400959.7
ENST00000367025.8
TRAF3IP3
TRAF3 interacting protein 3
chr1_+_32251239 2.83 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK
LCK proto-oncogene, Src family tyrosine kinase
chr19_+_7645895 2.81 ENST00000602355.1
STXBP2
syntaxin binding protein 2
chr1_+_206507520 2.65 ENST00000579436.7
RASSF5
Ras association domain family member 5
chr16_-_88706262 2.63 ENST00000562544.1
RNF166
ring finger protein 166
chr1_+_206507546 2.62 ENST00000580449.5
ENST00000581503.6
RASSF5
Ras association domain family member 5
chr1_+_209756149 2.61 ENST00000367026.7
TRAF3IP3
TRAF3 interacting protein 3
chr19_-_19628197 2.56 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
LPAR2
lysophosphatidic acid receptor 2
chrX_+_132023294 2.53 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
STK26
serine/threonine kinase 26
chr5_-_157575741 2.53 ENST00000517905.1
ADAM19
ADAM metallopeptidase domain 19
chr7_+_99374722 2.47 ENST00000418347.6
ENST00000429246.6
ENST00000417330.6
ENST00000431816.6
ENST00000458033.6
ENST00000451682.5
ENST00000427217.6
ENST00000646101.2
ARPC1B
actin related protein 2/3 complex subunit 1B
chr8_+_38901327 2.46 ENST00000519640.5
ENST00000617275.5
PLEKHA2
pleckstrin homology domain containing A2
chr7_+_99374675 2.43 ENST00000645391.1
ENST00000455009.6
ARPC1B
actin related protein 2/3 complex subunit 1B
chr11_+_64206663 2.33 ENST00000544997.5
ENST00000345728.10
ENST00000279227.9
FERMT3
fermitin family member 3
chr16_+_23835946 2.29 ENST00000321728.12
ENST00000643927.1
PRKCB
protein kinase C beta
chr12_-_89352395 2.28 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr8_+_38901218 2.18 ENST00000521746.5
ENST00000616927.4
PLEKHA2
pleckstrin homology domain containing A2
chr12_-_89352487 2.16 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr20_-_48827992 2.15 ENST00000371941.4
PREX1
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
chr1_+_172659095 2.13 ENST00000367721.3
ENST00000340030.4
FASLG
Fas ligand
chr19_-_10339610 2.12 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr19_+_7637099 1.99 ENST00000595950.5
ENST00000221283.10
ENST00000441779.6
ENST00000414284.6
STXBP2
syntaxin binding protein 2
chr6_-_30687200 1.99 ENST00000399199.7
PPP1R18
protein phosphatase 1 regulatory subunit 18
chr17_+_44352109 1.98 ENST00000586242.1
GRN
granulin precursor
chr2_+_85695368 1.95 ENST00000526018.1
GNLY
granulysin
chr14_+_92513766 1.95 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr1_-_24964984 1.94 ENST00000338888.3
ENST00000399916.5
RUNX3
RUNX family transcription factor 3
chr17_-_63699730 1.92 ENST00000578061.5
LIMD2
LIM domain containing 2
chrX_+_78945332 1.91 ENST00000544091.1
ENST00000171757.3
P2RY10
P2Y receptor family member 10
chr19_-_11578937 1.91 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
ACP5
acid phosphatase 5, tartrate resistant
chr6_-_30686624 1.90 ENST00000274853.8
PPP1R18
protein phosphatase 1 regulatory subunit 18
chr12_+_6951345 1.85 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
PTPN6
protein tyrosine phosphatase non-receptor type 6
chrX_+_132023580 1.79 ENST00000496850.1
STK26
serine/threonine kinase 26
chr17_-_45425620 1.77 ENST00000376922.6
ARHGAP27
Rho GTPase activating protein 27
chr19_+_35154715 1.76 ENST00000392218.6
ENST00000543307.5
ENST00000392219.7
ENST00000541435.6
ENST00000590686.5
ENST00000342879.7
ENST00000588699.5
FXYD5
FXYD domain containing ion transport regulator 5
chr11_-_417385 1.76 ENST00000332725.7
SIGIRR
single Ig and TIR domain containing
chr1_-_97920986 1.74 ENST00000370192.8
DPYD
dihydropyrimidine dehydrogenase
chr17_-_5234801 1.68 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr12_+_6951271 1.67 ENST00000456013.5
PTPN6
protein tyrosine phosphatase non-receptor type 6
chr1_+_155208690 1.67 ENST00000368376.8
MTX1
metaxin 1
chr10_+_87863595 1.67 ENST00000371953.8
PTEN
phosphatase and tensin homolog
chr17_+_74737211 1.65 ENST00000392612.7
ENST00000392610.5
RAB37
RAB37, member RAS oncogene family
chr7_-_150801325 1.65 ENST00000447204.6
TMEM176B
transmembrane protein 176B
chr7_+_150801522 1.62 ENST00000461345.5
TMEM176A
transmembrane protein 176A
chr17_+_74737238 1.60 ENST00000392613.10
ENST00000613645.1
RAB37
RAB37, member RAS oncogene family
chr16_+_81444799 1.60 ENST00000537098.8
CMIP
c-Maf inducing protein
chr16_+_28984795 1.59 ENST00000395461.7
LAT
linker for activation of T cells
chr14_+_21736136 1.57 ENST00000390426.2
TRAV4
T cell receptor alpha variable 4
chr7_-_87220567 1.50 ENST00000433078.5
TMEM243
transmembrane protein 243
chr7_+_150801695 1.50 ENST00000475536.5
ENST00000468689.2
TMEM176A
transmembrane protein 176A
chr19_+_44748673 1.46 ENST00000164227.10
BCL3
BCL3 transcription coactivator
chr22_-_30266839 1.44 ENST00000403463.1
ENST00000215781.3
OSM
oncostatin M
chr1_+_209756101 1.43 ENST00000479796.5
TRAF3IP3
TRAF3 interacting protein 3
chr19_+_35154914 1.43 ENST00000423817.7
FXYD5
FXYD domain containing ion transport regulator 5
chr12_+_6951250 1.40 ENST00000538715.5
PTPN6
protein tyrosine phosphatase non-receptor type 6
chrX_-_19887585 1.40 ENST00000397821.8
SH3KBP1
SH3 domain containing kinase binding protein 1
chr19_+_1067272 1.39 ENST00000590214.5
ARHGAP45
Rho GTPase activating protein 45
chr3_+_158732183 1.39 ENST00000486568.5
ENST00000495318.5
MFSD1
ENSG00000240207.7
major facilitator superfamily domain containing 1
novel transcript, antisense to RARRES1
chr5_+_56815534 1.39 ENST00000399503.4
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr19_+_1067493 1.38 ENST00000586866.5
ARHGAP45
Rho GTPase activating protein 45
chr22_+_19723525 1.38 ENST00000366425.4
GP1BB
glycoprotein Ib platelet subunit beta
chr19_+_1067144 1.37 ENST00000313093.7
ARHGAP45
Rho GTPase activating protein 45
chr17_-_5584448 1.35 ENST00000269280.8
ENST00000571451.6
ENST00000572272.6
ENST00000613500.4
ENST00000619223.4
ENST00000617618.4
ENST00000345221.7
ENST00000262467.10
NLRP1
NLR family pyrin domain containing 1
chr12_+_68610858 1.31 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B
RAP1B, member of RAS oncogene family
chr5_+_177303768 1.31 ENST00000303204.9
ENST00000503216.5
PRELID1
PRELI domain containing 1
chr1_+_155209213 1.31 ENST00000609421.1
MTX1
metaxin 1
chr8_-_100721851 1.30 ENST00000522658.6
PABPC1
poly(A) binding protein cytoplasmic 1
chr1_-_212699817 1.30 ENST00000243440.2
BATF3
basic leucine zipper ATF-like transcription factor 3
chr2_+_55232359 1.30 ENST00000449323.5
RPS27A
ribosomal protein S27a
chr8_-_100721942 1.29 ENST00000522387.5
PABPC1
poly(A) binding protein cytoplasmic 1
chr1_+_155208727 1.29 ENST00000316721.8
MTX1
metaxin 1
chr1_+_100352451 1.27 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
CDC14A
cell division cycle 14A
chr7_+_98211431 1.24 ENST00000609256.2
BHLHA15
basic helix-loop-helix family member a15
chr1_+_28887072 1.22 ENST00000647103.1
ENST00000642937.2
ENST00000646189.1
ENST00000644342.1
ENST00000373800.7
ENST00000649717.1
EPB41
erythrocyte membrane protein band 4.1
chr2_-_207165923 1.22 ENST00000309446.11
KLF7
Kruppel like factor 7
chr3_+_53161120 1.21 ENST00000394729.6
ENST00000330452.8
ENST00000652449.1
PRKCD
protein kinase C delta
chr11_-_6655788 1.21 ENST00000299441.5
DCHS1
dachsous cadherin-related 1
chr8_-_100722036 1.19 ENST00000518196.5
ENST00000519004.5
ENST00000519363.1
ENST00000318607.10
ENST00000520142.2
PABPC1
poly(A) binding protein cytoplasmic 1
chr1_-_161069666 1.19 ENST00000368016.7
ARHGAP30
Rho GTPase activating protein 30
chr1_+_28887166 1.19 ENST00000347529.7
EPB41
erythrocyte membrane protein band 4.1
chr10_+_102419189 1.18 ENST00000432590.5
FBXL15
F-box and leucine rich repeat protein 15
chr19_+_37907200 1.17 ENST00000222345.11
SIPA1L3
signal induced proliferation associated 1 like 3
chr11_-_47378527 1.17 ENST00000378538.8
SPI1
Spi-1 proto-oncogene
chr10_+_48684859 1.16 ENST00000360890.6
ENST00000325239.11
WDFY4
WDFY family member 4
chr11_-_47378391 1.15 ENST00000227163.8
SPI1
Spi-1 proto-oncogene
chr19_-_42220109 1.15 ENST00000595337.5
DEDD2
death effector domain containing 2
chr1_+_153774210 1.14 ENST00000271857.6
SLC27A3
solute carrier family 27 member 3
chr16_-_67936808 1.13 ENST00000358514.9
PSMB10
proteasome 20S subunit beta 10
chrX_+_49171889 1.12 ENST00000376327.6
PLP2
proteolipid protein 2
chr1_+_27959943 1.12 ENST00000675575.1
ENST00000373884.6
XKR8
XK related 8
chrX_+_49171918 1.12 ENST00000376322.7
PLP2
proteolipid protein 2
chr19_-_55325316 1.11 ENST00000591570.5
ENST00000326652.9
TMEM150B
transmembrane protein 150B
chrX_-_19887459 1.10 ENST00000379697.7
SH3KBP1
SH3 domain containing kinase binding protein 1
chr11_-_47378494 1.10 ENST00000533030.1
SPI1
Spi-1 proto-oncogene
chr19_-_1863497 1.09 ENST00000617223.1
ENST00000250916.6
KLF16
Kruppel like factor 16
chr12_-_14961610 1.09 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor beta
chr19_-_19628512 1.09 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr12_-_6606320 1.08 ENST00000642594.1
ENST00000644289.1
ENST00000645095.1
CHD4
chromodomain helicase DNA binding protein 4
chr6_+_33075952 1.07 ENST00000418931.7
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr12_+_68610956 1.07 ENST00000545720.6
RAP1B
RAP1B, member of RAS oncogene family
chr12_-_14961559 1.06 ENST00000228945.9
ENST00000541546.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr8_+_141128581 1.06 ENST00000519811.6
DENND3
DENN domain containing 3
chr11_-_47378479 1.05 ENST00000533968.1
SPI1
Spi-1 proto-oncogene
chr1_-_161069962 1.05 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr15_+_41332862 1.05 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
NUSAP1
nucleolar and spindle associated protein 1
chr9_+_87498491 1.05 ENST00000622514.4
DAPK1
death associated protein kinase 1
chr1_+_178725227 1.04 ENST00000367635.8
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr8_+_22578249 1.04 ENST00000456545.5
PDLIM2
PDZ and LIM domain 2
chr11_+_810227 1.03 ENST00000530398.1
RPLP2
ribosomal protein lateral stalk subunit P2
chr4_-_13544506 1.03 ENST00000382438.6
NKX3-2
NK3 homeobox 2
chr1_+_178725277 1.01 ENST00000324778.5
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr16_-_11256192 0.98 ENST00000644787.1
ENST00000332029.4
SOCS1
suppressor of cytokine signaling 1
chr9_+_126860625 0.98 ENST00000319119.4
ZBTB34
zinc finger and BTB domain containing 34
chr7_+_7968787 0.97 ENST00000223145.10
GLCCI1
glucocorticoid induced 1
chr19_+_55386338 0.97 ENST00000558131.1
ENST00000558752.1
RPL28
ribosomal protein L28
chrX_-_154805386 0.97 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
MPP1
membrane palmitoylated protein 1
chr2_+_176151543 0.96 ENST00000306324.4
HOXD4
homeobox D4
chrX_+_9465011 0.96 ENST00000645353.2
TBL1X
transducin beta like 1 X-linked
chr1_+_178725147 0.95 ENST00000367634.6
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr11_+_809961 0.95 ENST00000321153.9
ENST00000530797.5
RPLP2
ribosomal protein lateral stalk subunit P2
chr4_-_77819356 0.94 ENST00000649644.1
ENST00000504123.6
ENST00000515441.2
CNOT6L
CCR4-NOT transcription complex subunit 6 like
chr12_+_68611025 0.93 ENST00000541216.1
RAP1B
RAP1B, member of RAS oncogene family
chr1_+_40040720 0.92 ENST00000414893.5
ENST00000372792.7
ENST00000372805.8
ENST00000414281.5
ENST00000420216.5
ENST00000372798.5
ENST00000340450.7
ENST00000435719.5
ENST00000427843.5
ENST00000417287.5
ENST00000424977.1
CAP1
cyclase associated actin cytoskeleton regulatory protein 1
chr9_-_71768386 0.91 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chr14_+_71586261 0.89 ENST00000358550.6
SIPA1L1
signal induced proliferation associated 1 like 1
chr8_-_8893548 0.89 ENST00000276282.7
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr8_-_100721583 0.88 ENST00000610907.2
ENST00000677140.1
ENST00000677787.1
ENST00000679197.1
ENST00000519100.6
PABPC1
poly(A) binding protein cytoplasmic 1
chr1_-_161069857 0.88 ENST00000368013.8
ARHGAP30
Rho GTPase activating protein 30
chr1_-_97921042 0.88 ENST00000306031.5
DPYD
dihydropyrimidine dehydrogenase
chr15_-_56243829 0.88 ENST00000559447.8
ENST00000673997.1
RFX7
regulatory factor X7
chr14_+_75428011 0.88 ENST00000651602.1
ENST00000559060.5
JDP2
Jun dimerization protein 2
chr7_-_128031422 0.86 ENST00000249363.4
LRRC4
leucine rich repeat containing 4
chr22_+_31496387 0.86 ENST00000443011.5
ENST00000400288.7
ENST00000400289.5
ENST00000444859.5
SFI1
SFI1 centrin binding protein
chr8_+_133191029 0.85 ENST00000250160.11
CCN4
cellular communication network factor 4
chr17_+_77281429 0.83 ENST00000591198.5
ENST00000427177.6
SEPTIN9
septin 9
chr14_-_91253925 0.83 ENST00000531499.2
GPR68
G protein-coupled receptor 68
chr12_-_14961256 0.83 ENST00000541380.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr3_-_50503597 0.83 ENST00000266039.7
ENST00000424201.7
CACNA2D2
calcium voltage-gated channel auxiliary subunit alpha2delta 2
chr3_-_52231190 0.82 ENST00000494383.1
ENSG00000173366.11
novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein
chr19_+_41883173 0.81 ENST00000599846.5
ENST00000354532.8
ENST00000347545.8
ARHGEF1
Rho guanine nucleotide exchange factor 1
chr10_+_11005301 0.81 ENST00000416382.6
ENST00000631460.1
ENST00000631816.1
CELF2
CUGBP Elav-like family member 2
chr22_+_31944500 0.81 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
chr18_+_3450036 0.81 ENST00000546979.5
ENST00000343820.10
ENST00000551402.1
ENST00000577543.5
TGIF1
TGFB induced factor homeobox 1
chr9_-_112890868 0.81 ENST00000374228.5
SLC46A2
solute carrier family 46 member 2
chr2_-_73284431 0.80 ENST00000521871.5
ENST00000520530.3
FBXO41
F-box protein 41
chr5_-_177303675 0.80 ENST00000393611.6
ENST00000303270.6
ENST00000303251.11
RAB24
RAB24, member RAS oncogene family
chr17_+_7844915 0.80 ENST00000570632.1
KDM6B
lysine demethylase 6B
chr1_-_15585015 0.79 ENST00000375826.4
AGMAT
agmatinase
chr12_-_52601458 0.79 ENST00000537672.6
ENST00000293745.7
KRT72
keratin 72
chr19_-_11578917 0.79 ENST00000649386.1
ACP5
acid phosphatase 5, tartrate resistant
chr6_+_20403679 0.78 ENST00000535432.2
E2F3
E2F transcription factor 3
chr4_-_77819615 0.78 ENST00000512485.6
CNOT6L
CCR4-NOT transcription complex subunit 6 like
chr7_-_87220520 0.78 ENST00000455575.1
TMEM243
transmembrane protein 243
chr22_+_31944527 0.78 ENST00000248975.6
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
chr3_+_42502592 0.78 ENST00000438259.6
ENST00000543411.5
ENST00000439731.5
ENST00000325123.5
VIPR1
vasoactive intestinal peptide receptor 1
chr7_-_27102669 0.78 ENST00000222718.7
HOXA2
homeobox A2
chr4_+_26860809 0.77 ENST00000465503.6
ENST00000467087.7
STIM2
stromal interaction molecule 2
chr16_-_71289367 0.77 ENST00000434935.7
ENST00000565850.1
ENST00000568910.1
CMTR2
cap methyltransferase 2
chr2_+_202634960 0.77 ENST00000392238.3
FAM117B
family with sequence similarity 117 member B
chrX_-_154805516 0.76 ENST00000413259.7
MPP1
membrane palmitoylated protein 1
chr19_+_7395166 0.76 ENST00000594665.2
ENST00000617428.4
ARHGEF18
Rho/Rac guanine nucleotide exchange factor 18
chr7_-_65982205 0.75 ENST00000421103.5
ENST00000304895.9
GUSB
glucuronidase beta
chr9_+_87497852 0.75 ENST00000408954.8
DAPK1
death associated protein kinase 1
chr7_-_25180278 0.75 ENST00000283905.8
ENST00000409280.5
ENST00000415598.5
C7orf31
chromosome 7 open reading frame 31
chr9_-_120877167 0.74 ENST00000373896.8
ENST00000312189.10
PHF19
PHD finger protein 19
chr8_-_58659534 0.74 ENST00000427130.6
NSMAF
neutral sphingomyelinase activation associated factor
chr16_+_30949054 0.74 ENST00000318663.5
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr19_+_7395112 0.74 ENST00000319670.14
ARHGEF18
Rho/Rac guanine nucleotide exchange factor 18
chr14_+_22871732 0.74 ENST00000359591.9
LRP10
LDL receptor related protein 10
chr4_+_77157189 0.73 ENST00000316355.10
ENST00000502280.5
CCNG2
cyclin G2
chr10_+_26438317 0.73 ENST00000376236.9
APBB1IP
amyloid beta precursor protein binding family B member 1 interacting protein
chr11_+_117327829 0.73 ENST00000533153.5
ENST00000278935.8
ENST00000525416.5
CEP164
centrosomal protein 164
chr17_+_48908461 0.73 ENST00000508468.2
UBE2Z
ubiquitin conjugating enzyme E2 Z
chr19_-_35900532 0.72 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKBID
NFKB inhibitor delta
chr2_+_184598520 0.72 ENST00000302277.7
ZNF804A
zinc finger protein 804A
chr2_-_207166159 0.71 ENST00000426163.5
KLF7
Kruppel like factor 7
chr3_+_9749940 0.71 ENST00000302003.11
ENST00000349503.9
ENST00000302036.11
ENST00000344629.12
ENST00000339511.9
OGG1
8-oxoguanine DNA glycosylase
chr16_+_81645352 0.70 ENST00000398040.8
CMIP
c-Maf inducing protein
chr4_+_26860778 0.70 ENST00000467011.6
STIM2
stromal interaction molecule 2
chr19_-_19663664 0.70 ENST00000357324.11
ATP13A1
ATPase 13A1
chr11_+_66070256 0.68 ENST00000320580.9
PACS1
phosphofurin acidic cluster sorting protein 1
chrX_+_30653359 0.68 ENST00000378943.7
ENST00000378946.7
ENST00000427190.6
GK
glycerol kinase
chr9_-_131276499 0.68 ENST00000372271.4
FAM78A
family with sequence similarity 78 member A
chr22_-_46537593 0.68 ENST00000262738.9
ENST00000674500.2
CELSR1
cadherin EGF LAG seven-pass G-type receptor 1
chr18_+_3449620 0.68 ENST00000405385.7
TGIF1
TGFB induced factor homeobox 1
chr22_+_44677044 0.68 ENST00000006251.11
PRR5
proline rich 5
chr14_-_23010122 0.67 ENST00000397377.5
ENST00000397379.7
ENST00000341470.8
ENST00000555998.5
ENST00000299088.11
ENST00000397376.6
ENST00000553675.5
ENST00000553931.5
ENST00000555575.5
ENST00000553958.5
ENST00000555098.5
ENST00000556419.5
ENST00000553606.5
ENST00000554179.5
ENST00000397382.8
C14orf93
chromosome 14 open reading frame 93
chr10_-_58267868 0.67 ENST00000373935.4
IPMK
inositol polyphosphate multikinase
chr16_-_71289609 0.67 ENST00000338099.9
ENST00000563876.1
CMTR2
cap methyltransferase 2
chr3_+_23917170 0.67 ENST00000643707.1
RPL15
ribosomal protein L15
chr16_-_28211476 0.66 ENST00000569951.1
ENST00000565698.5
XPO6
exportin 6
chr1_+_154405326 0.66 ENST00000368485.8
IL6R
interleukin 6 receptor
chr12_+_121804689 0.66 ENST00000619791.1
ENST00000267197.9
SETD1B
SET domain containing 1B, histone lysine methyltransferase
chr12_-_6606427 0.66 ENST00000642879.1
CHD4
chromodomain helicase DNA binding protein 4
chr9_+_113580912 0.65 ENST00000471324.6
RGS3
regulator of G protein signaling 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.9 4.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.9 2.6 GO:0006212 uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.7 2.0 GO:0002818 intracellular defense response(GO:0002818)
0.6 4.5 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.6 2.5 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.6 1.7 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.5 4.9 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 3.0 GO:0071461 cellular response to redox state(GO:0071461)
0.5 1.5 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.5 1.4 GO:0036451 cap mRNA methylation(GO:0036451)
0.5 1.4 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.4 2.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.4 1.2 GO:0003192 mitral valve formation(GO:0003192)
0.4 5.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.3 3.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 2.4 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.3 4.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 3.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 1.2 GO:2000755 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.3 0.8 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.3 1.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.2 1.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 1.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.9 GO:2000595 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.2 0.9 GO:0002384 hepatic immune response(GO:0002384)
0.2 2.3 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2 0.8 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 1.9 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 7.9 GO:0030033 microvillus assembly(GO:0030033)
0.2 0.5 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 1.3 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 1.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 3.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.3 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 1.7 GO:0072553 terminal button organization(GO:0072553)
0.1 0.5 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.8 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.1 1.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.5 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 1.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 1.0 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 2.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.5 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.5 GO:2000607 regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.8 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.5 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.5 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 1.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.9 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 8.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.7 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.4 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.8 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.6 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 2.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.5 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 5.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 1.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.5 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.6 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 3.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 1.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.2 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 9.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.0 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 3.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.7 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 1.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.4 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 1.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 1.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 1.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 1.7 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.6 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0018963 phthalate metabolic process(GO:0018963)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 1.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.7 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 1.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 2.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0061205 alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 1.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.7 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 2.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 4.0 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.4 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 5.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.7 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0060947 positive regulation of transcription via serum response element binding(GO:0010735) cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 1.8 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 1.6 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:1904903 abscission(GO:0009838) ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 2.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 2.9 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.8 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 9.3 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 1.2 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.6 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.4 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 1.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.3 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0036284 tubulobulbar complex(GO:0036284)
0.7 6.8 GO:0044194 cytolytic granule(GO:0044194)
0.4 4.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 1.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 4.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.2 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 1.3 GO:0060091 kinocilium(GO:0060091)
0.1 1.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.5 GO:0032449 CBM complex(GO:0032449)
0.1 13.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 2.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 2.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 7.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 6.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 2.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.3 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 1.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 2.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 2.1 GO:0032420 stereocilium(GO:0032420)
0.0 3.3 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.9 GO:0045095 keratin filament(GO:0045095)
0.0 1.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.7 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 3.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 7.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.6 GO:0005776 autophagosome(GO:0005776)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 3.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.6 1.7 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity(GO:0034039)
0.6 1.7 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.5 4.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.5 1.4 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.4 2.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 3.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 3.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 4.1 GO:0051525 NFAT protein binding(GO:0051525)
0.3 0.8 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 0.7 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.2 1.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 4.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.9 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 0.6 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 1.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 4.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 2.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.5 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.2 4.7 GO:0008494 translation activator activity(GO:0008494)
0.2 3.1 GO:0008199 ferric iron binding(GO:0008199)
0.2 0.8 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.4 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.1 4.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 5.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 6.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.7 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.4 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.4 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.5 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 2.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.6 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 2.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 3.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.2 GO:0019956 chemokine binding(GO:0019956)
0.0 2.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 1.1 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 8.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 5.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.0 2.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 1.2 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 4.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 7.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.3 GO:0017016 Ras GTPase binding(GO:0017016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 13.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.3 PID EPO PATHWAY EPO signaling pathway
0.1 5.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 6.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 5.7 PID AURORA A PATHWAY Aurora A signaling
0.1 1.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.9 ST STAT3 PATHWAY STAT3 Pathway
0.1 2.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 4.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 7.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.6 PID ATR PATHWAY ATR signaling pathway
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3 7.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 1.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 4.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 3.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 3.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 4.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 7.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.4 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 6.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 4.9 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 2.1 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling