Illumina Body Map 2 (GSE30611)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
TFAP2C | hg38_v1_chr20_+_56629296_56629321 | 0.03 | 8.9e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 39.2 | GO:0043312 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
0.1 | 24.3 | GO:0038096 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
0.1 | 10.6 | GO:0032945 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
1.3 | 9.1 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.3 | 9.1 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
0.3 | 8.3 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
0.1 | 8.0 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.1 | 7.2 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
0.2 | 6.5 | GO:0071800 | podosome assembly(GO:0071800) |
0.1 | 5.2 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 23.6 | GO:0000139 | Golgi membrane(GO:0000139) |
0.1 | 19.4 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.1 | 13.4 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.1 | 11.3 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
0.0 | 9.3 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.9 | 8.7 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
0.1 | 7.9 | GO:0070821 | tertiary granule membrane(GO:0070821) |
0.1 | 7.8 | GO:0035577 | azurophil granule membrane(GO:0035577) |
0.6 | 7.1 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
0.1 | 7.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 12.9 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.2 | 12.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.7 | 9.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.8 | 8.7 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
0.0 | 8.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.1 | 8.3 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 8.2 | GO:0003924 | GTPase activity(GO:0003924) |
0.0 | 7.4 | GO:0002020 | protease binding(GO:0002020) |
0.1 | 6.9 | GO:0003823 | antigen binding(GO:0003823) |
0.0 | 5.4 | GO:0017124 | SH3 domain binding(GO:0017124) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 24.3 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.1 | 16.6 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
0.2 | 10.4 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
0.2 | 10.0 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
0.1 | 9.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
0.1 | 8.2 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
0.1 | 7.7 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
0.1 | 6.4 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.2 | 5.8 | PID S1P S1P4 PATHWAY | S1P4 pathway |
0.1 | 5.7 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 11.0 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.3 | 10.3 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.1 | 8.0 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 7.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.2 | 7.5 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.1 | 7.2 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.1 | 6.0 | REACTOME SIGNAL AMPLIFICATION | Genes involved in Signal amplification |
0.1 | 5.9 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
0.2 | 5.6 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 4.8 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |