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Illumina Body Map 2 (GSE30611)

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Results for TFAP2E

Z-value: 0.51

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Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
TFAP2E
ENSG00000116819.9 transcription factor AP-2 epsilon

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Ehg38_v1_chr1_+_35573308_35573319-0.354.7e-02Click!

Activity profile of TFAP2E motif

Sorted Z-values of TFAP2E motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_116829898 1.60 ENST00000227667.8
ENST00000375345.3
APOC3
apolipoprotein C3
chr3_+_52779916 1.11 ENST00000537050.5
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chrX_+_49171889 0.77 ENST00000376327.6
PLP2
proteolipid protein 2
chrX_+_49171918 0.76 ENST00000376322.7
PLP2
proteolipid protein 2
chr11_+_47215032 0.70 ENST00000622090.4
ENST00000378600.7
ENST00000378603.7
DDB2
damage specific DNA binding protein 2
chr11_-_66289007 0.63 ENST00000431556.6
ENST00000528575.1
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr19_+_4969105 0.61 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
KDM4B
lysine demethylase 4B
chr4_+_153466324 0.60 ENST00000409663.7
ENST00000409959.8
TMEM131L
transmembrane 131 like
chr11_-_66289125 0.58 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
YIF1A
Yip1 interacting factor homolog A, membrane trafficking protein
chr15_+_84817346 0.56 ENST00000258888.6
ALPK3
alpha kinase 3
chr1_+_17308194 0.55 ENST00000375453.5
ENST00000375448.4
PADI4
peptidyl arginine deiminase 4
chr8_+_22392821 0.52 ENST00000520832.1
SLC39A14
solute carrier family 39 member 14
chr19_+_45001430 0.51 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB
RELB proto-oncogene, NF-kB subunit
chr6_+_42564060 0.51 ENST00000372903.6
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr10_-_96720485 0.48 ENST00000339364.10
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr11_+_3855629 0.46 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
STIM1
stromal interaction molecule 1
chr19_-_45886120 0.44 ENST00000302165.5
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr2_-_74529670 0.43 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor
chr17_-_35088818 0.42 ENST00000414419.6
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr3_+_152269103 0.42 ENST00000459747.1
MBNL1
muscleblind like splicing regulator 1
chr11_-_72041792 0.42 ENST00000537930.5
NUMA1
nuclear mitotic apparatus protein 1
chr2_+_231708511 0.42 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
PTMA
prothymosin alpha
chr6_+_42563981 0.41 ENST00000372899.6
ENST00000372901.2
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr3_+_152268920 0.41 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
MBNL1
muscleblind like splicing regulator 1
chr4_-_152679984 0.40 ENST00000304385.8
ENST00000504064.1
TMEM154
transmembrane protein 154
chr19_+_54449612 0.40 ENST00000443957.5
LENG8
leukocyte receptor cluster member 8
chr19_-_43465596 0.40 ENST00000244333.4
LYPD3
LY6/PLAUR domain containing 3
chr13_-_75482151 0.40 ENST00000377636.8
TBC1D4
TBC1 domain family member 4
chr19_+_50432885 0.40 ENST00000357701.6
MYBPC2
myosin binding protein C2
chr6_+_7107597 0.39 ENST00000379933.7
ENST00000491191.5
ENST00000471433.5
RREB1
ras responsive element binding protein 1
chr10_-_124092445 0.39 ENST00000346248.7
CHST15
carbohydrate sulfotransferase 15
chr10_-_77638369 0.38 ENST00000372443.6
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr6_+_7107941 0.37 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
RREB1
ras responsive element binding protein 1
chr9_+_133636355 0.37 ENST00000393056.8
DBH
dopamine beta-hydroxylase
chr19_+_38304105 0.37 ENST00000588605.5
ENST00000301246.10
C19orf33
chromosome 19 open reading frame 33
chr6_-_18264475 0.36 ENST00000515742.2
ENST00000651624.1
ENST00000507591.2
ENST00000652689.1
ENST00000244776.11
ENST00000503715.5
DEK
DEK proto-oncogene
chr11_-_72041945 0.36 ENST00000543009.5
NUMA1
nuclear mitotic apparatus protein 1
chr11_-_72041522 0.35 ENST00000544238.5
NUMA1
nuclear mitotic apparatus protein 1
chr7_-_140924900 0.35 ENST00000646891.1
ENST00000644969.2
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr1_-_113812448 0.34 ENST00000612242.4
ENST00000261441.9
RSBN1
round spermatid basic protein 1
chr10_-_124092390 0.34 ENST00000628426.1
CHST15
carbohydrate sulfotransferase 15
chr17_-_35089212 0.33 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr10_-_131981948 0.33 ENST00000633835.1
BNIP3
BCL2 interacting protein 3
chrX_+_153724847 0.32 ENST00000218104.6
ABCD1
ATP binding cassette subfamily D member 1
chr5_-_180071708 0.32 ENST00000522208.6
ENST00000521389.6
RNF130
ring finger protein 130
chr5_-_151924824 0.32 ENST00000455880.2
GLRA1
glycine receptor alpha 1
chr19_-_10503186 0.32 ENST00000592055.2
ENST00000171111.10
KEAP1
kelch like ECH associated protein 1
chr9_+_133636378 0.31 ENST00000263611.3
DBH
dopamine beta-hydroxylase
chr13_-_75482114 0.31 ENST00000377625.6
ENST00000431480.6
TBC1D4
TBC1 domain family member 4
chr1_+_228208024 0.31 ENST00000570156.7
ENST00000680850.1
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr5_-_151924846 0.29 ENST00000274576.9
GLRA1
glycine receptor alpha 1
chr1_-_113812254 0.29 ENST00000616024.4
ENST00000615321.1
RSBN1
round spermatid basic protein 1
chr1_-_40862354 0.28 ENST00000372638.4
CITED4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr11_-_65857543 0.28 ENST00000534784.1
CFL1
cofilin 1
chr10_-_77637902 0.28 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr16_-_28495519 0.27 ENST00000569430.7
CLN3
CLN3 lysosomal/endosomal transmembrane protein, battenin
chr17_-_41612757 0.27 ENST00000301653.9
ENST00000593067.1
KRT16
keratin 16
chr6_+_31586835 0.26 ENST00000211921.11
LST1
leukocyte specific transcript 1
chr2_+_73202570 0.25 ENST00000398468.4
NOTO
notochord homeobox
chr1_+_228208054 0.25 ENST00000284548.16
ENST00000422127.5
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chrX_+_116436599 0.24 ENST00000598581.3
SLC6A14
solute carrier family 6 member 14
chr11_-_71252492 0.24 ENST00000601538.6
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr8_-_143430727 0.24 ENST00000333480.3
MAFA
MAF bZIP transcription factor A
chr2_-_177264686 0.24 ENST00000397062.8
ENST00000430047.1
NFE2L2
nuclear factor, erythroid 2 like 2
chr1_+_8945858 0.23 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
CA6
carbonic anhydrase 6
chr6_+_31586680 0.22 ENST00000339530.8
LST1
leukocyte specific transcript 1
chr6_+_31586859 0.22 ENST00000433492.5
LST1
leukocyte specific transcript 1
chr9_+_135714425 0.22 ENST00000473941.5
ENST00000486577.6
KCNT1
potassium sodium-activated channel subfamily T member 1
chr7_+_151085858 0.21 ENST00000463381.5
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr4_-_81471898 0.21 ENST00000335927.11
ENST00000264400.7
ENST00000504863.1
RASGEF1B
RasGEF domain family member 1B
chr22_-_38700655 0.21 ENST00000216039.9
JOSD1
Josephin domain containing 1
chr20_+_2840694 0.21 ENST00000380469.7
ENST00000380445.8
ENST00000453689.5
ENST00000417508.1
VPS16
VPS16 core subunit of CORVET and HOPS complexes
chr11_-_47848539 0.21 ENST00000526870.1
NUP160
nucleoporin 160
chr5_-_180072086 0.20 ENST00000261947.4
RNF130
ring finger protein 130
chr11_-_82901507 0.20 ENST00000533126.1
PRCP
prolylcarboxypeptidase
chr3_-_48088824 0.20 ENST00000439356.2
ENST00000395734.7
ENST00000426837.6
MAP4
microtubule associated protein 4
chr6_-_87702221 0.19 ENST00000257787.6
AKIRIN2
akirin 2
chr2_-_23927048 0.19 ENST00000439915.1
ATAD2B
ATPase family AAA domain containing 2B
chr1_-_93847150 0.19 ENST00000370244.5
BCAR3
BCAR3 adaptor protein, NSP family member
chr7_+_73433761 0.19 ENST00000344575.5
FZD9
frizzled class receptor 9
chr3_-_136752361 0.19 ENST00000480733.1
ENST00000629124.2
ENST00000383202.7
ENST00000236698.9
ENST00000434713.6
STAG1
stromal antigen 1
chr1_+_3069160 0.19 ENST00000511072.5
PRDM16
PR/SET domain 16
chr1_-_11691608 0.18 ENST00000376667.7
MAD2L2
mitotic arrest deficient 2 like 2
chr9_+_126326809 0.18 ENST00000361171.8
ENST00000489637.3
MVB12B
multivesicular body subunit 12B
chrX_+_129738942 0.18 ENST00000371106.4
XPNPEP2
X-prolyl aminopeptidase 2
chr2_-_37324696 0.17 ENST00000443187.1
PRKD3
protein kinase D3
chr11_-_35420017 0.17 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
SLC1A2
solute carrier family 1 member 2
chr3_+_122795039 0.17 ENST00000261038.6
SLC49A4
solute carrier family 49 member 4
chr1_-_43453792 0.17 ENST00000372434.5
ENST00000486909.1
HYI
hydroxypyruvate isomerase (putative)
chr1_-_43453902 0.17 ENST00000372430.9
ENST00000372432.5
ENST00000583037.5
HYI
hydroxypyruvate isomerase (putative)
chr1_+_966466 0.17 ENST00000379410.8
ENST00000379407.7
ENST00000379409.6
PLEKHN1
pleckstrin homology domain containing N1
chr8_+_17922974 0.17 ENST00000517730.5
ENST00000518537.5
ENST00000523055.5
ENST00000519253.5
PCM1
pericentriolar material 1
chrX_-_49079702 0.17 ENST00000636049.1
ENST00000474053.6
ENST00000635003.1
WDR45
WD repeat domain 45
chr1_-_11691646 0.17 ENST00000235310.7
MAD2L2
mitotic arrest deficient 2 like 2
chr22_+_31212207 0.16 ENST00000406516.5
ENST00000331728.9
LIMK2
LIM domain kinase 2
chr1_-_224434750 0.16 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WDR26
WD repeat domain 26
chr17_+_63622406 0.16 ENST00000579585.5
ENST00000361733.8
ENST00000584573.5
ENST00000361357.7
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr7_-_140924699 0.16 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
BRAF
B-Raf proto-oncogene, serine/threonine kinase
chr11_+_64206663 0.16 ENST00000544997.5
ENST00000345728.10
ENST00000279227.9
FERMT3
fermitin family member 3
chr1_-_43453716 0.16 ENST00000372433.5
HYI
hydroxypyruvate isomerase (putative)
chr22_-_45977154 0.16 ENST00000339464.9
WNT7B
Wnt family member 7B
chr2_-_240892007 0.16 ENST00000402775.6
ENST00000307486.12
MAB21L4
mab-21 like 4
chr22_+_31248402 0.15 ENST00000333611.8
ENST00000340552.4
LIMK2
LIM domain kinase 2
chr8_+_17922837 0.15 ENST00000325083.12
PCM1
pericentriolar material 1
chr22_-_38700920 0.15 ENST00000456626.1
ENST00000412832.1
ENST00000683374.1
JOSD1
Josephin domain containing 1
chr16_-_381935 0.15 ENST00000431232.7
ENST00000250930.7
PGAP6
post-glycosylphosphatidylinositol attachment to proteins 6
chr3_+_105367212 0.15 ENST00000472644.6
ALCAM
activated leukocyte cell adhesion molecule
chr5_+_134648772 0.15 ENST00000398844.7
ENST00000322887.8
SEC24A
SEC24 homolog A, COPII coat complex component
chrX_+_41085436 0.15 ENST00000324545.9
ENST00000378308.7
USP9X
ubiquitin specific peptidase 9 X-linked
chr7_+_130070518 0.15 ENST00000335420.10
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr11_-_35419899 0.14 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
SLC1A2
solute carrier family 1 member 2
chr18_-_47930559 0.14 ENST00000587269.5
SMAD2
SMAD family member 2
chr7_+_148590760 0.14 ENST00000307003.3
C7orf33
chromosome 7 open reading frame 33
chr4_-_81471855 0.13 ENST00000436139.6
ENST00000613784.1
RASGEF1B
RasGEF domain family member 1B
chr2_+_190648852 0.13 ENST00000416973.1
ENST00000426601.1
NAB1
NGFI-A binding protein 1
chr19_-_38773432 0.13 ENST00000599035.1
ENST00000378626.5
LGALS7
galectin 7
chr9_-_109320949 0.12 ENST00000374557.4
EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr12_-_14567714 0.12 ENST00000240617.10
PLBD1
phospholipase B domain containing 1
chr17_-_76726753 0.12 ENST00000617192.4
JMJD6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr8_-_102655707 0.12 ENST00000285407.11
KLF10
Kruppel like factor 10
chr3_-_49411917 0.11 ENST00000454011.7
ENST00000445425.6
ENST00000422781.6
ENST00000418115.6
ENST00000678921.2
ENST00000676712.2
RHOA
ras homolog family member A
chr11_-_35419462 0.11 ENST00000643522.1
SLC1A2
solute carrier family 1 member 2
chr19_+_8390316 0.11 ENST00000328024.11
ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr8_+_25184758 0.11 ENST00000481100.5
DOCK5
dedicator of cytokinesis 5
chr11_-_62612280 0.11 ENST00000466671.5
ENST00000466886.5
EML3
EMAP like 3
chr11_-_47848313 0.10 ENST00000530326.5
ENST00000528071.5
NUP160
nucleoporin 160
chr17_-_44111253 0.10 ENST00000591714.5
HDAC5
histone deacetylase 5
chr17_+_39667964 0.10 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr11_-_77411883 0.10 ENST00000528203.5
ENST00000528592.5
ENST00000528633.1
ENST00000529248.5
PAK1
p21 (RAC1) activated kinase 1
chr14_-_63543288 0.10 ENST00000555899.1
PPP2R5E
protein phosphatase 2 regulatory subunit B'epsilon
chr3_-_48088800 0.10 ENST00000423088.5
MAP4
microtubule associated protein 4
chr14_-_63543328 0.09 ENST00000337537.8
PPP2R5E
protein phosphatase 2 regulatory subunit B'epsilon
chr11_-_47848467 0.09 ENST00000378460.6
NUP160
nucleoporin 160
chr11_-_27506751 0.09 ENST00000278193.7
ENST00000524596.1
LIN7C
lin-7 homolog C, crumbs cell polarity complex component
chr9_-_21077938 0.09 ENST00000380232.4
IFNB1
interferon beta 1
chr22_+_31248323 0.09 ENST00000425203.1
LIMK2
LIM domain kinase 2
chr7_+_29194757 0.09 ENST00000222792.11
CHN2
chimerin 2
chrX_-_107000062 0.09 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr8_+_124450806 0.08 ENST00000328599.4
TRMT12
tRNA methyltransferase 12 homolog
chr11_-_65857007 0.08 ENST00000527344.5
CFL1
cofilin 1
chr9_-_34662654 0.08 ENST00000259631.5
CCL27
C-C motif chemokine ligand 27
chr9_+_4984985 0.08 ENST00000476574.5
JAK2
Janus kinase 2
chr7_+_32495447 0.08 ENST00000318709.9
ENST00000409301.5
ENST00000640103.1
AVL9
AVL9 cell migration associated
chr1_-_11805977 0.07 ENST00000376486.3
MTHFR
methylenetetrahydrofolate reductase
chr12_-_56630293 0.07 ENST00000546695.5
ENST00000549884.6
BAZ2A
bromodomain adjacent to zinc finger domain 2A
chr17_+_39668447 0.07 ENST00000269582.3
ENST00000581428.1
PNMT
phenylethanolamine N-methyltransferase
chr19_-_42255119 0.06 ENST00000222329.9
ENST00000594664.1
ERF
ENSG00000268643.2
ETS2 repressor factor
novel protein
chr11_-_35419542 0.06 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
SLC1A2
solute carrier family 1 member 2
chr3_+_111072020 0.06 ENST00000486596.5
ENST00000493615.5
NECTIN3
nectin cell adhesion molecule 3
chr19_+_3572927 0.06 ENST00000333651.11
ENST00000417382.5
HMG20B
high mobility group 20B
chr5_+_142108753 0.06 ENST00000253814.6
NDFIP1
Nedd4 family interacting protein 1
chr1_+_34759737 0.06 ENST00000339480.3
GJB4
gap junction protein beta 4
chr15_+_23565705 0.06 ENST00000568252.1
ENST00000649065.1
MKRN3
makorin ring finger protein 3
chr2_+_74834113 0.06 ENST00000290573.7
HK2
hexokinase 2
chr9_-_15307181 0.05 ENST00000506891.1
ENST00000512701.6
ENST00000380850.8
ENST00000297615.9
TTC39B
tetratricopeptide repeat domain 39B
chr9_-_122213903 0.05 ENST00000464484.3
LHX6
LIM homeobox 6
chr11_-_61295289 0.05 ENST00000335613.10
VWCE
von Willebrand factor C and EGF domains
chr2_-_23927107 0.05 ENST00000238789.10
ATAD2B
ATPase family AAA domain containing 2B
chr13_-_30465224 0.05 ENST00000399494.5
HMGB1
high mobility group box 1
chr20_-_2840623 0.04 ENST00000360652.7
ENST00000448755.5
PCED1A
PC-esterase domain containing 1A
chr7_-_23014099 0.04 ENST00000432176.7
ENST00000440481.6
FAM126A
family with sequence similarity 126 member A
chr20_+_6767678 0.04 ENST00000378827.5
BMP2
bone morphogenetic protein 2
chr10_+_91220603 0.04 ENST00000336126.6
PCGF5
polycomb group ring finger 5
chr19_+_49157741 0.04 ENST00000598691.5
TRPM4
transient receptor potential cation channel subfamily M member 4
chr11_-_35419098 0.04 ENST00000606205.6
ENST00000645303.1
SLC1A2
solute carrier family 1 member 2
chr4_+_6909775 0.04 ENST00000409757.9
TBC1D14
TBC1 domain family member 14
chr9_+_35605234 0.03 ENST00000336395.6
TESK1
testis associated actin remodelling kinase 1
chr19_+_3572777 0.03 ENST00000416526.5
HMG20B
high mobility group 20B
chr9_+_35605277 0.03 ENST00000620767.4
TESK1
testis associated actin remodelling kinase 1
chrX_+_132023294 0.03 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
STK26
serine/threonine kinase 26
chr1_+_33256479 0.03 ENST00000539719.6
ENST00000483388.5
ZNF362
zinc finger protein 362
chr3_+_42654470 0.03 ENST00000680014.1
ZBTB47
zinc finger and BTB domain containing 47
chr12_+_29149092 0.03 ENST00000551451.5
FAR2
fatty acyl-CoA reductase 2
chr15_-_65422894 0.03 ENST00000352385.3
IGDCC4
immunoglobulin superfamily DCC subclass member 4
chr7_+_816609 0.03 ENST00000457378.6
ENST00000389574.7
ENST00000452783.6
ENST00000435699.5
ENST00000440380.5
ENST00000439679.5
ENST00000424128.5
SUN1
Sad1 and UNC84 domain containing 1
chr11_-_65856944 0.03 ENST00000524553.5
CFL1
cofilin 1
chr2_+_218859794 0.02 ENST00000233948.4
WNT6
Wnt family member 6
chr19_+_54449180 0.02 ENST00000439657.5
ENST00000326764.10
ENST00000376514.6
ENST00000436479.1
LENG8
leukocyte receptor cluster member 8
chr1_-_11805924 0.02 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase
chr1_+_150149819 0.02 ENST00000369124.5
PLEKHO1
pleckstrin homology domain containing O1
chr3_+_50155305 0.02 ENST00000002829.8
ENST00000426511.5
SEMA3F
semaphorin 3F
chr19_-_54173151 0.02 ENST00000619895.5
TMC4
transmembrane channel like 4
chr13_-_30465923 0.01 ENST00000341423.10
ENST00000326004.4
HMGB1
high mobility group box 1
chr4_+_6909444 0.01 ENST00000448507.5
TBC1D14
TBC1 domain family member 14
chr9_+_125261788 0.01 ENST00000461379.5
ENST00000297933.11
ENST00000394084.5
ENST00000394105.6
ENST00000470056.5
ENST00000394083.6
ENST00000495955.5
ENST00000467750.5
GAPVD1
GTPase activating protein and VPS9 domains 1
chr14_+_103385450 0.01 ENST00000416682.6
MARK3
microtubule affinity regulating kinase 3
chr11_-_35419213 0.01 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
SLC1A2
solute carrier family 1 member 2
chr14_+_103385506 0.01 ENST00000303622.13
MARK3
microtubule affinity regulating kinase 3
chr20_-_25390776 0.01 ENST00000376542.8
ENST00000339157.10
ABHD12
abhydrolase domain containing 12, lysophospholipase
chr7_-_23014074 0.01 ENST00000409763.1
ENST00000679826.1
ENST00000409923.5
ENST00000681766.1
FAM126A
family with sequence similarity 126 member A
chr9_+_130265745 0.01 ENST00000683500.1
HMCN2
hemicentin 2
chr10_+_22325610 0.00 ENST00000416820.5
BMI1
BMI1 proto-oncogene, polycomb ring finger

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.3 0.8 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.7 GO:0046333 octopamine biosynthetic process(GO:0006589) homoiothermy(GO:0042309) octopamine metabolic process(GO:0046333)
0.2 0.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.5 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.5 GO:2000301 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 0.4 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.6 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.7 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.6 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.0 GO:0003130 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0 0.7 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0070079 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.0 0.4 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.5 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 1.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.2 1.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 1.1 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 0.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 0.5 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.2 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.7 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.9 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0033746 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.6 GO:0019956 chemokine binding(GO:0019956)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport