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Illumina Body Map 2 (GSE30611)

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Results for TFAP2E

Z-value: 0.51

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Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
ENSG00000116819.9 transcription factor AP-2 epsilon

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP2Ehg38_v1_chr1_+_35573308_35573319-0.354.7e-02Click!

Activity profile of TFAP2E motif

Sorted Z-values of TFAP2E motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_116829898 1.60 ENST00000227667.8
ENST00000375345.3
apolipoprotein C3
chr3_+_52779916 1.11 ENST00000537050.5
inter-alpha-trypsin inhibitor heavy chain 1
chrX_+_49171889 0.77 ENST00000376327.6
proteolipid protein 2
chrX_+_49171918 0.76 ENST00000376322.7
proteolipid protein 2
chr11_+_47215032 0.70 ENST00000622090.4
ENST00000378600.7
ENST00000378603.7
damage specific DNA binding protein 2
chr11_-_66289007 0.63 ENST00000431556.6
ENST00000528575.1
Yip1 interacting factor homolog A, membrane trafficking protein
chr19_+_4969105 0.61 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
lysine demethylase 4B
chr4_+_153466324 0.60 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr11_-_66289125 0.58 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
Yip1 interacting factor homolog A, membrane trafficking protein
chr15_+_84817346 0.56 ENST00000258888.6
alpha kinase 3
chr1_+_17308194 0.55 ENST00000375453.5
ENST00000375448.4
peptidyl arginine deiminase 4
chr8_+_22392821 0.52 ENST00000520832.1
solute carrier family 39 member 14
chr19_+_45001430 0.51 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr6_+_42564060 0.51 ENST00000372903.6
ubiquitin protein ligase E3 component n-recognin 2
chr10_-_96720485 0.48 ENST00000339364.10
phosphoinositide-3-kinase adaptor protein 1
chr11_+_3855629 0.46 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
stromal interaction molecule 1
chr19_-_45886120 0.44 ENST00000302165.5
interferon regulatory factor 2 binding protein 1
chr2_-_74529670 0.43 ENST00000377526.4
AUP1 lipid droplet regulating VLDL assembly factor
chr17_-_35088818 0.42 ENST00000414419.6
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr3_+_152269103 0.42 ENST00000459747.1
muscleblind like splicing regulator 1
chr11_-_72041792 0.42 ENST00000537930.5
nuclear mitotic apparatus protein 1
chr2_+_231708511 0.42 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
prothymosin alpha
chr6_+_42563981 0.41 ENST00000372899.6
ENST00000372901.2
ubiquitin protein ligase E3 component n-recognin 2
chr3_+_152268920 0.41 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
muscleblind like splicing regulator 1
chr4_-_152679984 0.40 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr19_+_54449612 0.40 ENST00000443957.5
leukocyte receptor cluster member 8
chr19_-_43465596 0.40 ENST00000244333.4
LY6/PLAUR domain containing 3
chr13_-_75482151 0.40 ENST00000377636.8
TBC1 domain family member 4
chr19_+_50432885 0.40 ENST00000357701.6
myosin binding protein C2
chr6_+_7107597 0.39 ENST00000379933.7
ENST00000491191.5
ENST00000471433.5
ras responsive element binding protein 1
chr10_-_124092445 0.39 ENST00000346248.7
carbohydrate sulfotransferase 15
chr10_-_77638369 0.38 ENST00000372443.6
potassium calcium-activated channel subfamily M alpha 1
chr6_+_7107941 0.37 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
ras responsive element binding protein 1
chr9_+_133636355 0.37 ENST00000393056.8
dopamine beta-hydroxylase
chr19_+_38304105 0.37 ENST00000588605.5
ENST00000301246.10
chromosome 19 open reading frame 33
chr6_-_18264475 0.36 ENST00000515742.2
ENST00000651624.1
ENST00000507591.2
ENST00000652689.1
ENST00000244776.11
ENST00000503715.5
DEK proto-oncogene
chr11_-_72041945 0.36 ENST00000543009.5
nuclear mitotic apparatus protein 1
chr11_-_72041522 0.35 ENST00000544238.5
nuclear mitotic apparatus protein 1
chr7_-_140924900 0.35 ENST00000646891.1
ENST00000644969.2
B-Raf proto-oncogene, serine/threonine kinase
chr1_-_113812448 0.34 ENST00000612242.4
ENST00000261441.9
round spermatid basic protein 1
chr10_-_124092390 0.34 ENST00000628426.1
carbohydrate sulfotransferase 15
chr17_-_35089212 0.33 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr10_-_131981948 0.33 ENST00000633835.1
BCL2 interacting protein 3
chrX_+_153724847 0.32 ENST00000218104.6
ATP binding cassette subfamily D member 1
chr5_-_180071708 0.32 ENST00000522208.6
ENST00000521389.6
ring finger protein 130
chr5_-_151924824 0.32 ENST00000455880.2
glycine receptor alpha 1
chr19_-_10503186 0.32 ENST00000592055.2
ENST00000171111.10
kelch like ECH associated protein 1
chr9_+_133636378 0.31 ENST00000263611.3
dopamine beta-hydroxylase
chr13_-_75482114 0.31 ENST00000377625.6
ENST00000431480.6
TBC1 domain family member 4
chr1_+_228208024 0.31 ENST00000570156.7
ENST00000680850.1
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr5_-_151924846 0.29 ENST00000274576.9
glycine receptor alpha 1
chr1_-_113812254 0.29 ENST00000616024.4
ENST00000615321.1
round spermatid basic protein 1
chr1_-_40862354 0.28 ENST00000372638.4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
chr11_-_65857543 0.28 ENST00000534784.1
cofilin 1
chr10_-_77637902 0.28 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr16_-_28495519 0.27 ENST00000569430.7
CLN3 lysosomal/endosomal transmembrane protein, battenin
chr17_-_41612757 0.27 ENST00000301653.9
ENST00000593067.1
keratin 16
chr6_+_31586835 0.26 ENST00000211921.11
leukocyte specific transcript 1
chr2_+_73202570 0.25 ENST00000398468.4
notochord homeobox
chr1_+_228208054 0.25 ENST00000284548.16
ENST00000422127.5
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chrX_+_116436599 0.24 ENST00000598581.3
solute carrier family 6 member 14
chr11_-_71252492 0.24 ENST00000601538.6
SH3 and multiple ankyrin repeat domains 2
chr8_-_143430727 0.24 ENST00000333480.3
MAF bZIP transcription factor A
chr2_-_177264686 0.24 ENST00000397062.8
ENST00000430047.1
nuclear factor, erythroid 2 like 2
chr1_+_8945858 0.23 ENST00000549778.5
ENST00000377443.7
ENST00000480186.7
ENST00000377436.6
ENST00000377442.3
carbonic anhydrase 6
chr6_+_31586680 0.22 ENST00000339530.8
leukocyte specific transcript 1
chr6_+_31586859 0.22 ENST00000433492.5
leukocyte specific transcript 1
chr9_+_135714425 0.22 ENST00000473941.5
ENST00000486577.6
potassium sodium-activated channel subfamily T member 1
chr7_+_151085858 0.21 ENST00000463381.5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr4_-_81471898 0.21 ENST00000335927.11
ENST00000264400.7
ENST00000504863.1
RasGEF domain family member 1B
chr22_-_38700655 0.21 ENST00000216039.9
Josephin domain containing 1
chr20_+_2840694 0.21 ENST00000380469.7
ENST00000380445.8
ENST00000453689.5
ENST00000417508.1
VPS16 core subunit of CORVET and HOPS complexes
chr11_-_47848539 0.21 ENST00000526870.1
nucleoporin 160
chr5_-_180072086 0.20 ENST00000261947.4
ring finger protein 130
chr11_-_82901507 0.20 ENST00000533126.1
prolylcarboxypeptidase
chr3_-_48088824 0.20 ENST00000439356.2
ENST00000395734.7
ENST00000426837.6
microtubule associated protein 4
chr6_-_87702221 0.19 ENST00000257787.6
akirin 2
chr2_-_23927048 0.19 ENST00000439915.1
ATPase family AAA domain containing 2B
chr1_-_93847150 0.19 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr7_+_73433761 0.19 ENST00000344575.5
frizzled class receptor 9
chr3_-_136752361 0.19 ENST00000480733.1
ENST00000629124.2
ENST00000383202.7
ENST00000236698.9
ENST00000434713.6
stromal antigen 1
chr1_+_3069160 0.19 ENST00000511072.5
PR/SET domain 16
chr1_-_11691608 0.18 ENST00000376667.7
mitotic arrest deficient 2 like 2
chr9_+_126326809 0.18 ENST00000361171.8
ENST00000489637.3
multivesicular body subunit 12B
chrX_+_129738942 0.18 ENST00000371106.4
X-prolyl aminopeptidase 2
chr2_-_37324696 0.17 ENST00000443187.1
protein kinase D3
chr11_-_35420017 0.17 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
solute carrier family 1 member 2
chr3_+_122795039 0.17 ENST00000261038.6
solute carrier family 49 member 4
chr1_-_43453792 0.17 ENST00000372434.5
ENST00000486909.1
hydroxypyruvate isomerase (putative)
chr1_-_43453902 0.17 ENST00000372430.9
ENST00000372432.5
ENST00000583037.5
hydroxypyruvate isomerase (putative)
chr1_+_966466 0.17 ENST00000379410.8
ENST00000379407.7
ENST00000379409.6
pleckstrin homology domain containing N1
chr8_+_17922974 0.17 ENST00000517730.5
ENST00000518537.5
ENST00000523055.5
ENST00000519253.5
pericentriolar material 1
chrX_-_49079702 0.17 ENST00000636049.1
ENST00000474053.6
ENST00000635003.1
WD repeat domain 45
chr1_-_11691646 0.17 ENST00000235310.7
mitotic arrest deficient 2 like 2
chr22_+_31212207 0.16 ENST00000406516.5
ENST00000331728.9
LIM domain kinase 2
chr1_-_224434750 0.16 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WD repeat domain 26
chr17_+_63622406 0.16 ENST00000579585.5
ENST00000361733.8
ENST00000584573.5
ENST00000361357.7
mitogen-activated protein kinase kinase kinase 3
chr7_-_140924699 0.16 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
B-Raf proto-oncogene, serine/threonine kinase
chr11_+_64206663 0.16 ENST00000544997.5
ENST00000345728.10
ENST00000279227.9
fermitin family member 3
chr1_-_43453716 0.16 ENST00000372433.5
hydroxypyruvate isomerase (putative)
chr22_-_45977154 0.16 ENST00000339464.9
Wnt family member 7B
chr2_-_240892007 0.16 ENST00000402775.6
ENST00000307486.12
mab-21 like 4
chr22_+_31248402 0.15 ENST00000333611.8
ENST00000340552.4
LIM domain kinase 2
chr8_+_17922837 0.15 ENST00000325083.12
pericentriolar material 1
chr22_-_38700920 0.15 ENST00000456626.1
ENST00000412832.1
ENST00000683374.1
Josephin domain containing 1
chr16_-_381935 0.15 ENST00000431232.7
ENST00000250930.7
post-glycosylphosphatidylinositol attachment to proteins 6
chr3_+_105367212 0.15 ENST00000472644.6
activated leukocyte cell adhesion molecule
chr5_+_134648772 0.15 ENST00000398844.7
ENST00000322887.8
SEC24 homolog A, COPII coat complex component
chrX_+_41085436 0.15 ENST00000324545.9
ENST00000378308.7
ubiquitin specific peptidase 9 X-linked
chr7_+_130070518 0.15 ENST00000335420.10
ENST00000463413.1
kelch domain containing 10
chr11_-_35419899 0.14 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
solute carrier family 1 member 2
chr18_-_47930559 0.14 ENST00000587269.5
SMAD family member 2
chr7_+_148590760 0.14 ENST00000307003.3
chromosome 7 open reading frame 33
chr4_-_81471855 0.13 ENST00000436139.6
ENST00000613784.1
RasGEF domain family member 1B
chr2_+_190648852 0.13 ENST00000416973.1
ENST00000426601.1
NGFI-A binding protein 1
chr19_-_38773432 0.13 ENST00000599035.1
ENST00000378626.5
galectin 7
chr9_-_109320949 0.12 ENST00000374557.4
erythrocyte membrane protein band 4.1 like 4B
chr12_-_14567714 0.12 ENST00000240617.10
phospholipase B domain containing 1
chr17_-_76726753 0.12 ENST00000617192.4
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr8_-_102655707 0.12 ENST00000285407.11
Kruppel like factor 10
chr3_-_49411917 0.11 ENST00000454011.7
ENST00000445425.6
ENST00000422781.6
ENST00000418115.6
ENST00000678921.2
ENST00000676712.2
ras homolog family member A
chr11_-_35419462 0.11 ENST00000643522.1
solute carrier family 1 member 2
chr19_+_8390316 0.11 ENST00000328024.11
ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr8_+_25184758 0.11 ENST00000481100.5
dedicator of cytokinesis 5
chr11_-_62612280 0.11 ENST00000466671.5
ENST00000466886.5
EMAP like 3
chr11_-_47848313 0.10 ENST00000530326.5
ENST00000528071.5
nucleoporin 160
chr17_-_44111253 0.10 ENST00000591714.5
histone deacetylase 5
chr17_+_39667964 0.10 ENST00000394246.1
phenylethanolamine N-methyltransferase
chr11_-_77411883 0.10 ENST00000528203.5
ENST00000528592.5
ENST00000528633.1
ENST00000529248.5
p21 (RAC1) activated kinase 1
chr14_-_63543288 0.10 ENST00000555899.1
protein phosphatase 2 regulatory subunit B'epsilon
chr3_-_48088800 0.10 ENST00000423088.5
microtubule associated protein 4
chr14_-_63543328 0.09 ENST00000337537.8
protein phosphatase 2 regulatory subunit B'epsilon
chr11_-_47848467 0.09 ENST00000378460.6
nucleoporin 160
chr11_-_27506751 0.09 ENST00000278193.7
ENST00000524596.1
lin-7 homolog C, crumbs cell polarity complex component
chr9_-_21077938 0.09 ENST00000380232.4
interferon beta 1
chr22_+_31248323 0.09 ENST00000425203.1
LIM domain kinase 2
chr7_+_29194757 0.09 ENST00000222792.11
chimerin 2
chrX_-_107000062 0.09 ENST00000255495.7
MORC family CW-type zinc finger 4
chr8_+_124450806 0.08 ENST00000328599.4
tRNA methyltransferase 12 homolog
chr11_-_65857007 0.08 ENST00000527344.5
cofilin 1
chr9_-_34662654 0.08 ENST00000259631.5
C-C motif chemokine ligand 27
chr9_+_4984985 0.08 ENST00000476574.5
Janus kinase 2
chr7_+_32495447 0.08 ENST00000318709.9
ENST00000409301.5
ENST00000640103.1
AVL9 cell migration associated
chr1_-_11805977 0.07 ENST00000376486.3
methylenetetrahydrofolate reductase
chr12_-_56630293 0.07 ENST00000546695.5
ENST00000549884.6
bromodomain adjacent to zinc finger domain 2A
chr17_+_39668447 0.07 ENST00000269582.3
ENST00000581428.1
phenylethanolamine N-methyltransferase
chr19_-_42255119 0.06 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr11_-_35419542 0.06 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
solute carrier family 1 member 2
chr3_+_111072020 0.06 ENST00000486596.5
ENST00000493615.5
nectin cell adhesion molecule 3
chr19_+_3572927 0.06 ENST00000333651.11
ENST00000417382.5
high mobility group 20B
chr5_+_142108753 0.06 ENST00000253814.6
Nedd4 family interacting protein 1
chr1_+_34759737 0.06 ENST00000339480.3
gap junction protein beta 4
chr15_+_23565705 0.06 ENST00000568252.1
ENST00000649065.1
makorin ring finger protein 3
chr2_+_74834113 0.06 ENST00000290573.7
hexokinase 2
chr9_-_15307181 0.05 ENST00000506891.1
ENST00000512701.6
ENST00000380850.8
ENST00000297615.9
tetratricopeptide repeat domain 39B
chr9_-_122213903 0.05 ENST00000464484.3
LIM homeobox 6
chr11_-_61295289 0.05 ENST00000335613.10
von Willebrand factor C and EGF domains
chr2_-_23927107 0.05 ENST00000238789.10
ATPase family AAA domain containing 2B
chr13_-_30465224 0.05 ENST00000399494.5
high mobility group box 1
chr20_-_2840623 0.04 ENST00000360652.7
ENST00000448755.5
PC-esterase domain containing 1A
chr7_-_23014099 0.04 ENST00000432176.7
ENST00000440481.6
family with sequence similarity 126 member A
chr20_+_6767678 0.04 ENST00000378827.5
bone morphogenetic protein 2
chr10_+_91220603 0.04 ENST00000336126.6
polycomb group ring finger 5
chr19_+_49157741 0.04 ENST00000598691.5
transient receptor potential cation channel subfamily M member 4
chr11_-_35419098 0.04 ENST00000606205.6
ENST00000645303.1
solute carrier family 1 member 2
chr4_+_6909775 0.04 ENST00000409757.9
TBC1 domain family member 14
chr9_+_35605234 0.03 ENST00000336395.6
testis associated actin remodelling kinase 1
chr19_+_3572777 0.03 ENST00000416526.5
high mobility group 20B
chr9_+_35605277 0.03 ENST00000620767.4
testis associated actin remodelling kinase 1
chrX_+_132023294 0.03 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr1_+_33256479 0.03 ENST00000539719.6
ENST00000483388.5
zinc finger protein 362
chr3_+_42654470 0.03 ENST00000680014.1
zinc finger and BTB domain containing 47
chr12_+_29149092 0.03 ENST00000551451.5
fatty acyl-CoA reductase 2
chr15_-_65422894 0.03 ENST00000352385.3
immunoglobulin superfamily DCC subclass member 4
chr7_+_816609 0.03 ENST00000457378.6
ENST00000389574.7
ENST00000452783.6
ENST00000435699.5
ENST00000440380.5
ENST00000439679.5
ENST00000424128.5
Sad1 and UNC84 domain containing 1
chr11_-_65856944 0.03 ENST00000524553.5
cofilin 1
chr2_+_218859794 0.02 ENST00000233948.4
Wnt family member 6
chr19_+_54449180 0.02 ENST00000439657.5
ENST00000326764.10
ENST00000376514.6
ENST00000436479.1
leukocyte receptor cluster member 8
chr1_-_11805924 0.02 ENST00000418034.1
methylenetetrahydrofolate reductase
chr1_+_150149819 0.02 ENST00000369124.5
pleckstrin homology domain containing O1
chr3_+_50155305 0.02 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr19_-_54173151 0.02 ENST00000619895.5
transmembrane channel like 4
chr13_-_30465923 0.01 ENST00000341423.10
ENST00000326004.4
high mobility group box 1
chr4_+_6909444 0.01 ENST00000448507.5
TBC1 domain family member 14
chr9_+_125261788 0.01 ENST00000461379.5
ENST00000297933.11
ENST00000394084.5
ENST00000394105.6
ENST00000470056.5
ENST00000394083.6
ENST00000495955.5
ENST00000467750.5
GTPase activating protein and VPS9 domains 1
chr14_+_103385450 0.01 ENST00000416682.6
microtubule affinity regulating kinase 3
chr11_-_35419213 0.01 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
solute carrier family 1 member 2
chr14_+_103385506 0.01 ENST00000303622.13
microtubule affinity regulating kinase 3
chr20_-_25390776 0.01 ENST00000376542.8
ENST00000339157.10
abhydrolase domain containing 12, lysophospholipase
chr7_-_23014074 0.01 ENST00000409763.1
ENST00000679826.1
ENST00000409923.5
ENST00000681766.1
family with sequence similarity 126 member A
chr9_+_130265745 0.01 ENST00000683500.1
hemicentin 2
chr10_+_22325610 0.00 ENST00000416820.5
BMI1 proto-oncogene, polycomb ring finger

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.3 0.8 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 0.7 GO:0046333 octopamine biosynthetic process(GO:0006589) homoiothermy(GO:0042309) octopamine metabolic process(GO:0046333)
0.2 0.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.5 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.5 GO:2000301 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 0.4 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.6 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.7 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.6 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.0 GO:0003130 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0 0.7 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0070079 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.0 0.4 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.5 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 1.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.2 1.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 1.1 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 0.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.2 0.5 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.2 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.7 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.9 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0033746 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 1.6 GO:0019956 chemokine binding(GO:0019956)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport