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Illumina Body Map 2 (GSE30611)

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Results for TFCP2

Z-value: 1.33

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Transcription factors associated with TFCP2

Gene Symbol Gene ID Gene Info
ENSG00000135457.10 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2hg38_v1_chr12_-_51172779_51172912-0.096.2e-01Click!

Activity profile of TFCP2 motif

Sorted Z-values of TFCP2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_47957824 4.63 ENST00000300557.3
proline rich 15 like
chr21_-_39349048 4.54 ENST00000380748.5
ENST00000380749.10
high mobility group nucleosome binding domain 1
chr9_-_101435760 4.20 ENST00000647789.2
ENST00000616752.1
aldolase, fructose-bisphosphate B
chr11_-_128867268 3.94 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr11_-_128867364 3.87 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr14_-_106374129 3.66 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr14_-_106422175 3.34 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr14_-_106335613 3.10 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr2_+_88885397 2.86 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr14_-_106639589 2.81 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr3_+_186717348 2.66 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr2_+_97713568 2.46 ENST00000264972.10
zeta chain of T cell receptor associated protein kinase 70
chr19_-_51372269 2.34 ENST00000593572.5
ENST00000595157.1
natural killer cell granule protein 7
chr22_+_22818994 2.29 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr22_-_37175049 2.28 ENST00000453962.5
ENST00000429622.5
ENST00000445595.1
interleukin 2 receptor subunit beta
chr12_+_93569814 2.24 ENST00000340600.6
suppressor of cytokine signaling 2
chr14_-_106277039 2.22 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr6_+_31528956 2.22 ENST00000376191.3
mitochondrial coiled-coil domain 1
chr19_+_1071194 2.20 ENST00000543365.5
Rho GTPase activating protein 45
chr10_+_5048748 2.18 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr6_-_132734692 2.15 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr19_-_51372640 2.09 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr11_+_2902258 2.00 ENST00000649076.2
ENST00000449793.6
solute carrier family 22 member 18
chr6_-_52803807 1.99 ENST00000334575.6
glutathione S-transferase alpha 1
chr17_-_5234801 1.99 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr20_+_38346474 1.97 ENST00000217407.3
lipopolysaccharide binding protein
chr17_+_70104848 1.88 ENST00000392670.5
potassium inwardly rectifying channel subfamily J member 16
chr16_+_85902689 1.87 ENST00000563180.1
ENST00000564617.5
ENST00000564803.5
interferon regulatory factor 8
chr3_+_101849505 1.83 ENST00000326151.9
ENST00000326172.9
NFKB inhibitor zeta
chr16_+_85899121 1.83 ENST00000268638.10
ENST00000565552.1
interferon regulatory factor 8
chr14_+_75280078 1.74 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr7_-_47582076 1.71 ENST00000311160.14
tensin 3
chr2_+_108288869 1.70 ENST00000251481.11
ENST00000438339.5
ENST00000409880.5
ENST00000437390.6
sulfotransferase family 1C member 2
chr10_+_44911316 1.69 ENST00000544540.5
ENST00000389583.5
transmembrane protein 72
chr9_-_114930508 1.67 ENST00000223795.3
ENST00000618336.4
TNF superfamily member 8
chr3_+_46354072 1.66 ENST00000445132.3
ENST00000421659.1
C-C motif chemokine receptor 2
chr10_-_88851809 1.64 ENST00000371930.5
ankyrin repeat domain 22
chr10_-_75235917 1.63 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr19_+_40586774 1.62 ENST00000594298.5
ENST00000597396.5
SH3KBP1 binding protein 1
chr6_+_35297809 1.60 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr11_+_58927701 1.58 ENST00000317391.8
glycine-N-acyltransferase like 1
chr1_+_153357846 1.58 ENST00000368738.4
S100 calcium binding protein A9
chr6_-_73521549 1.56 ENST00000676547.1
eukaryotic translation elongation factor 1 alpha 1
chr19_-_51372686 1.53 ENST00000595217.1
natural killer cell granule protein 7
chr12_-_57767057 1.53 ENST00000228606.9
cytochrome P450 family 27 subfamily B member 1
chr17_+_70075317 1.52 ENST00000589377.1
potassium inwardly rectifying channel subfamily J member 16
chr17_+_70104991 1.48 ENST00000587698.5
ENST00000587892.1
potassium inwardly rectifying channel subfamily J member 16
chr14_-_105940235 1.42 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr3_+_186666003 1.42 ENST00000232003.5
histidine rich glycoprotein
chr6_-_134174853 1.41 ENST00000475719.6
ENST00000367857.9
ENST00000237305.11
serum/glucocorticoid regulated kinase 1
chr17_-_35981487 1.41 ENST00000611905.2
C-C motif chemokine ligand 16
chr15_-_21742799 1.40 ENST00000622410.2
novel protein, identical to IGHV4-4
chr17_+_47253817 1.40 ENST00000559488.7
ENST00000571680.1
integrin subunit beta 3
chr2_-_162071183 1.38 ENST00000678668.1
dipeptidyl peptidase 4
chr11_+_2902388 1.38 ENST00000380574.5
solute carrier family 22 member 18
chr18_+_22914115 1.37 ENST00000579124.5
ENST00000577588.5
ENST00000582354.5
ENST00000581819.5
RB binding protein 8, endonuclease
chrX_+_30653359 1.37 ENST00000378943.7
ENST00000378946.7
ENST00000427190.6
glycerol kinase
chr8_+_8701891 1.34 ENST00000519106.2
claudin 23
chr22_+_24607658 1.33 ENST00000451366.5
ENST00000428855.5
gamma-glutamyltransferase 1
chrX_-_48919015 1.31 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr2_+_108288639 1.31 ENST00000326853.9
sulfotransferase family 1C member 2
chr20_-_47786553 1.28 ENST00000467815.5
ENST00000359930.8
ENST00000484875.5
sulfatase 2
chr11_+_57598184 1.28 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr12_+_93570381 1.28 ENST00000549206.5
suppressor of cytokine signaling 2
chr7_-_47582558 1.27 ENST00000457718.5
tensin 3
chr3_-_184248935 1.27 ENST00000446569.1
ENST00000397676.8
ALG3 alpha-1,3- mannosyltransferase
chr3_-_150546403 1.27 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr1_+_172659095 1.25 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr16_-_67159881 1.24 ENST00000345057.9
TNFRSF1A associated via death domain
chrX_+_106693751 1.23 ENST00000418562.5
ring finger protein 128
chr2_-_89160329 1.22 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr11_+_57597563 1.20 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr1_-_153540694 1.19 ENST00000368717.2
S100 calcium binding protein A5
chr16_-_82011444 1.19 ENST00000328945.7
ENST00000532128.5
short chain dehydrogenase/reductase family 42E, member 1
chr17_-_29566962 1.16 ENST00000307201.5
abhydrolase domain containing 15
chr19_-_43527189 1.15 ENST00000292147.7
ENST00000600651.5
ETHE1 persulfide dioxygenase
chr6_+_142301926 1.15 ENST00000296932.13
ENST00000367609.8
adhesion G protein-coupled receptor G6
chr11_+_60378475 1.15 ENST00000358246.5
membrane spanning 4-domains A7
chr15_-_22185402 1.14 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr5_+_32712257 1.13 ENST00000507141.1
natriuretic peptide receptor 3
chr17_-_7179348 1.13 ENST00000573083.1
ENST00000574388.5
ENST00000269299.8
asialoglycoprotein receptor 1
chr15_+_58138169 1.12 ENST00000558772.5
aquaporin 9
chr2_+_191678122 1.12 ENST00000425611.9
ENST00000410026.7
nucleic acid binding protein 1
chr1_+_206083540 1.11 ENST00000603378.5
ENST00000603488.5
regulator of hemoglobinization and erythroid cell expansion
chrX_-_106903331 1.11 ENST00000411805.1
ENST00000276173.5
ripply transcriptional repressor 1
chr1_-_84574407 1.11 ENST00000370630.6
chitobiase
chr6_-_32666648 1.10 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr15_-_34343112 1.09 ENST00000557912.1
ENST00000328848.6
NOP10 ribonucleoprotein
chrX_+_30653478 1.09 ENST00000378945.7
ENST00000378941.4
glycerol kinase
chr19_-_3600581 1.09 ENST00000589966.1
thromboxane A2 receptor
chr6_+_31971831 1.08 ENST00000375331.7
ENST00000375333.3
serine/threonine kinase 19
chr2_-_61538290 1.08 ENST00000678790.1
exportin 1
chr20_-_63572455 1.07 ENST00000467148.1
helicase with zinc finger 2
chr11_+_60378494 1.06 ENST00000534016.5
membrane spanning 4-domains A7
chr16_-_68236069 1.06 ENST00000473183.7
ENST00000565858.5
epithelial splicing regulatory protein 2
chrX_+_119468436 1.06 ENST00000317881.9
solute carrier family 25 member 5
chrX_+_134373297 1.05 ENST00000332070.7
ENST00000370803.8
ENST00000625464.2
ENST00000370799.5
PHD finger protein 6
chr4_-_2933947 1.04 ENST00000514800.5
major facilitator superfamily domain containing 10
chr6_+_29550407 1.03 ENST00000641137.1
olfactory receptor family 2 subfamily I member 1 pseudogene
chr19_+_54630410 1.02 ENST00000396327.7
ENST00000324602.12
leukocyte immunoglobulin like receptor B1
chr8_-_63026179 1.02 ENST00000677919.1
gamma-glutamyl hydrolase
chr7_-_27147774 1.01 ENST00000222728.3
homeobox A6
chr19_+_15641280 1.00 ENST00000585846.1
cytochrome P450 family 4 subfamily F member 3
chr6_-_31729260 1.00 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr11_+_46381753 0.99 ENST00000407067.1
midkine
chr20_-_50636887 0.99 ENST00000045083.6
RIPOR family member 3
chr11_+_60378524 0.99 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr9_-_127937800 0.98 ENST00000373110.4
ENST00000314392.13
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr11_+_58927623 0.97 ENST00000525608.5
ENST00000526351.5
glycine-N-acyltransferase like 1
chr11_+_71998892 0.97 ENST00000393705.8
ENST00000393703.9
ENST00000337131.9
ENST00000620017.4
ENST00000531053.5
ENST00000404792.5
interleukin 18 binding protein
chr15_+_59611776 0.96 ENST00000396065.3
ENST00000560585.5
glucosaminyl (N-acetyl) transferase 3, mucin type
chr14_-_94770102 0.96 ENST00000238558.5
goosecoid homeobox
chr2_+_191678152 0.96 ENST00000409510.5
nucleic acid binding protein 1
chr2_-_61538180 0.95 ENST00000677150.1
ENST00000678182.1
ENST00000677928.1
ENST00000406957.5
exportin 1
chr11_-_47248835 0.95 ENST00000673604.1
ENST00000256997.9
acid phosphatase 2, lysosomal
chr19_-_36528232 0.94 ENST00000592282.1
ENST00000523638.6
zinc finger protein 260
chr14_-_22982544 0.93 ENST00000262713.7
ajuba LIM protein
chr11_-_93197932 0.93 ENST00000326402.9
solute carrier family 36 member 4
chr10_-_93482326 0.92 ENST00000359263.9
myoferlin
chr11_+_46381698 0.92 ENST00000395565.5
midkine
chr11_+_46381645 0.91 ENST00000617138.4
ENST00000395566.9
ENST00000395569.8
midkine
chr2_-_189582012 0.91 ENST00000427419.5
ENST00000455320.5
solute carrier family 40 member 1
chr18_+_58671439 0.90 ENST00000649217.2
MALT1 paracaspase
chr8_+_85245451 0.89 ENST00000321764.4
carbonic anhydrase 13
chr16_-_21440719 0.88 ENST00000521589.5
nuclear pore complex interacting protein family member B3
chr6_-_31729478 0.88 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr6_+_116461364 0.86 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr11_-_67374168 0.85 ENST00000533438.1
cardiotrophin like cytokine factor 1
chr10_-_93482194 0.85 ENST00000358334.9
ENST00000371488.3
myoferlin
chrX_-_119791620 0.84 ENST00000361575.4
ribosomal protein L39
chr20_+_36876119 0.84 ENST00000602922.5
ENST00000217320.8
TBC/LysM-associated domain containing 2
chr6_+_116254146 0.84 ENST00000430252.6
ENST00000647244.1
dermatan sulfate epimerase
chr14_+_52267683 0.83 ENST00000306051.3
ENST00000553372.1
prostaglandin D2 receptor
chr19_+_54630960 0.82 ENST00000396317.5
ENST00000396315.5
leukocyte immunoglobulin like receptor B1
chr12_+_6452024 0.82 ENST00000266556.8
ENST00000544021.5
TAP binding protein like
chr11_-_47248789 0.81 ENST00000529444.7
ENST00000672787.1
ENST00000672073.1
ENST00000672636.2
ENST00000527256.7
acid phosphatase 2, lysosomal
chr4_+_112297341 0.81 ENST00000504176.6
ENST00000650871.1
ENST00000177648.13
ENST00000458497.6
alpha kinase 1
chr2_+_90021567 0.80 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr21_+_33266350 0.79 ENST00000290200.7
interleukin 10 receptor subunit beta
chr16_+_56608577 0.79 ENST00000245185.6
ENST00000561491.1
metallothionein 2A
chr6_+_142302621 0.79 ENST00000541199.5
ENST00000435011.6
adhesion G protein-coupled receptor G6
chr11_-_85719111 0.79 ENST00000529581.5
ENST00000533577.1
synaptotagmin like 2
chr6_-_31729785 0.78 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr11_-_93197390 0.76 ENST00000529184.5
solute carrier family 36 member 4
chr2_-_187513641 0.76 ENST00000392365.5
ENST00000435414.5
tissue factor pathway inhibitor
chr16_-_788329 0.76 ENST00000563560.1
ENST00000569601.5
ENST00000565809.5
ENST00000007264.7
ENST00000565377.1
ENST00000567114.5
RNA pseudouridine synthase domain containing 1
chr2_+_112645930 0.75 ENST00000272542.8
solute carrier family 20 member 1
chr2_-_151289613 0.74 ENST00000243346.10
N-myc and STAT interactor
chr11_-_57567260 0.74 ENST00000526659.1
ENST00000527022.1
ubiquitin conjugating enzyme E2 L6
chr1_+_70221396 0.74 ENST00000395136.6
serine and arginine rich splicing factor 11
chr12_+_47223501 0.74 ENST00000549630.1
ENST00000551777.1
PC-esterase domain containing 1B
chr12_+_51951663 0.74 ENST00000257963.9
ENST00000541224.5
ENST00000426655.6
ENST00000536420.5
ENST00000415850.6
activin A receptor type 1B
chr3_+_107522936 0.74 ENST00000415149.6
ENST00000402543.5
ENST00000325805.13
ENST00000427402.5
BBX high mobility group box domain containing
chr11_-_62601223 0.73 ENST00000527204.5
metastasis associated 1 family member 2
chr3_+_16265330 0.73 ENST00000606098.1
oxidoreductase NAD binding domain containing 1
chr10_-_93482287 0.73 ENST00000371489.5
myoferlin
chr2_+_88897230 0.72 ENST00000390244.2
immunoglobulin kappa variable 5-2
chr15_+_75647877 0.72 ENST00000308527.6
sorting nexin 33
chr2_+_231707650 0.71 ENST00000409321.5
prothymosin alpha
chr19_+_54630497 0.70 ENST00000396332.8
ENST00000427581.6
leukocyte immunoglobulin like receptor B1
chr15_+_62066975 0.68 ENST00000355522.5
C2 calcium dependent domain containing 4A
chr6_+_33620329 0.68 ENST00000374316.9
inositol 1,4,5-trisphosphate receptor type 3
chr14_-_22982258 0.68 ENST00000555074.1
ENST00000361265.8
novel protein
ajuba LIM protein
chrX_+_106693838 0.67 ENST00000324342.7
ring finger protein 128
chr16_+_67159932 0.67 ENST00000518148.1
ENST00000258200.8
ENST00000519917.5
ENST00000517382.5
ENST00000521920.5
F-box and leucine rich repeat protein 8
chr10_-_102451536 0.66 ENST00000625129.1
chromosome 10 open reading frame 95
chr14_+_22007503 0.66 ENST00000390447.3
T cell receptor alpha variable 19
chr17_-_59151794 0.66 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr2_+_210556590 0.65 ENST00000233072.10
ENST00000619804.1
carbamoyl-phosphate synthase 1
chr16_-_75623225 0.65 ENST00000562374.1
ENST00000564657.2
ENST00000567281.5
ENST00000307921.7
adenosine deaminase tRNA specific 1
chr11_+_47248885 0.65 ENST00000395397.7
ENST00000405576.5
nuclear receptor subfamily 1 group H member 3
chr5_+_55160161 0.64 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr6_+_143060457 0.64 ENST00000367601.8
androgen induced 1
chrX_+_105822531 0.64 ENST00000243300.14
ENST00000536164.5
Nik related kinase
chr17_+_75784798 0.64 ENST00000589666.6
unk zinc finger
chr13_-_41061373 0.63 ENST00000405737.2
E74 like ETS transcription factor 1
chr6_-_2744126 0.63 ENST00000647417.1
myosin light chain kinase family member 4
chr14_+_22872304 0.63 ENST00000546834.5
LDL receptor related protein 10
chr12_+_56994485 0.62 ENST00000300098.3
G protein-coupled receptor 182
chr11_-_85719045 0.62 ENST00000533057.6
ENST00000533892.5
synaptotagmin like 2
chrX_-_53434341 0.62 ENST00000375298.4
ENST00000375304.9
ENST00000684692.1
ENST00000168216.11
hydroxysteroid 17-beta dehydrogenase 10
chr22_+_24607602 0.62 ENST00000447416.5
gamma-glutamyltransferase 1
chr6_+_63211446 0.61 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr2_-_61538516 0.61 ENST00000676771.1
ENST00000677814.1
ENST00000443240.5
ENST00000677556.1
ENST00000676553.1
exportin 1
chr16_+_74377878 0.61 ENST00000429990.1
nuclear pore complex interacting protein family member B15
chr13_+_52012375 0.61 ENST00000649708.2
ENST00000523764.1
ENST00000649340.2
ENST00000679544.1
ENST00000681053.1
ENST00000521508.2
ENST00000616513.1
ALG11 alpha-1,2-mannosyltransferase
chr15_-_65611236 0.60 ENST00000420799.7
ENST00000313182.6
ENST00000431261.6
ENST00000652388.1
ENST00000442903.3
integrator complex subunit 14
chr19_+_15508517 0.59 ENST00000269703.8
cytochrome P450 family 4 subfamily F member 22
chr17_-_42388360 0.59 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr7_-_149090690 0.58 ENST00000491431.2
ENST00000316286.13
zinc finger protein 786
chr4_-_128286787 0.58 ENST00000503588.1
progesterone receptor membrane component 2
chr11_-_57567617 0.57 ENST00000287156.9
ubiquitin conjugating enzyme E2 L6
chr19_+_48552159 0.57 ENST00000201586.7
sulfotransferase family 2B member 1
chr16_+_1680337 0.57 ENST00000566691.5
ENST00000382710.8
Jupiter microtubule associated homolog 2
chr20_-_5610980 0.56 ENST00000379019.7
glycerophosphocholine phosphodiesterase 1
chr17_-_42388467 0.56 ENST00000678792.1
ENST00000679166.1
ENST00000677442.1
ENST00000677723.1
ENST00000678905.1
ENST00000677479.1
ENST00000678043.1
ENST00000677152.1
ENST00000677603.1
ENST00000588969.5
ENST00000678535.1
ENST00000679185.1
ENST00000677030.1
ENST00000679014.1
ENST00000678044.1
ENST00000678827.1
signal transducer and activator of transcription 3
chr11_+_47248924 0.55 ENST00000481889.6
ENST00000436778.5
ENST00000531660.5
ENST00000407404.5
nuclear receptor subfamily 1 group H member 3
chr22_+_24607638 0.55 ENST00000432867.5
gamma-glutamyltransferase 1
chrX_-_48957548 0.55 ENST00000376488.8
ENST00000396743.7
ENST00000156084.8
OTU deubiquitinase 5
chr17_-_7179544 0.54 ENST00000619926.4
asialoglycoprotein receptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.7 2.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.6 2.6 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.6 2.5 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.6 1.7 GO:2000439 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.5 1.5 GO:0070564 positive regulation of vitamin D receptor signaling pathway(GO:0070564)
0.5 2.5 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.5 1.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.4 4.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.4 2.5 GO:0043366 beta selection(GO:0043366)
0.4 2.8 GO:0030421 defecation(GO:0030421)
0.4 1.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.4 1.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.4 3.4 GO:0046618 drug export(GO:0046618)
0.4 1.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.4 1.4 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.3 1.0 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.3 1.4 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.3 1.0 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.3 1.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 0.9 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 0.8 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.3 1.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 1.0 GO:1902524 negative regulation of interferon-alpha biosynthetic process(GO:0045355) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.3 1.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 1.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.2 1.2 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 1.4 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.2 2.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 1.1 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.2 0.7 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.2 1.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.6 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 0.8 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.2 2.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 1.1 GO:0001757 somite specification(GO:0001757)
0.2 2.2 GO:0015827 tryptophan transport(GO:0015827)
0.2 13.4 GO:0010107 potassium ion import(GO:0010107)
0.2 2.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.2 1.1 GO:0006863 purine nucleobase transport(GO:0006863)
0.2 1.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 2.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 1.0 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.2 1.2 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 1.0 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 3.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.4 GO:0033632 negative regulation of extracellular matrix disassembly(GO:0010716) regulation of cell-cell adhesion mediated by integrin(GO:0033632) psychomotor behavior(GO:0036343)
0.1 3.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 2.5 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 3.7 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 2.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 20.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 3.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.3 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 1.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.8 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 4.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 1.9 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 1.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.8 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 1.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:0006175 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175)
0.1 0.7 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.9 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.4 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1 1.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 1.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 1.9 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 2.6 GO:0051923 sulfation(GO:0051923)
0.1 1.5 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 0.4 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.1 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.1 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 2.0 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.1 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 1.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.7 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:2000173 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.6 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.5 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.0 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 1.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.0 1.0 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 3.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0097033 calcium ion transmembrane import into mitochondrion(GO:0036444) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 5.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414) apoptotic process involved in luteolysis(GO:0061364)
0.0 1.0 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 1.1 GO:0015893 drug transport(GO:0015893)
0.0 0.3 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
0.0 1.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 1.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 1.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 1.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.3 GO:0072520 cerebral cortex regionalization(GO:0021796) seminiferous tubule development(GO:0072520)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.8 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.7 GO:0010762 regulation of fibroblast migration(GO:0010762)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 1.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 2.1 GO:0070876 SOSS complex(GO:0070876)
0.3 0.8 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.3 1.1 GO:0071817 MMXD complex(GO:0071817)
0.2 1.4 GO:0032449 CBM complex(GO:0032449)
0.2 0.6 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 1.7 GO:0035976 AP1 complex(GO:0035976)
0.2 0.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.2 3.1 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.0 GO:0031415 NatA complex(GO:0031415)
0.1 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 6.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 4.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.9 GO:0005879 axonemal microtubule(GO:0005879)
0.1 2.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 6.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 9.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 3.4 GO:0005901 caveola(GO:0005901)
0.0 3.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 3.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.7 2.2 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.7 8.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.6 2.6 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.6 2.5 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.6 0.6 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.6 3.4 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.5 2.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.5 2.5 GO:0004370 glycerol kinase activity(GO:0004370)
0.5 2.3 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.4 1.7 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.4 1.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 3.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 3.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.4 1.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.3 1.0 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.3 1.0 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.3 1.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 1.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.3 1.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.3 1.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 0.9 GO:0097689 iron channel activity(GO:0097689)
0.3 1.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.3 1.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.3 1.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.2 4.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 1.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 1.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 1.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.7 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 1.2 GO:0032810 sterol response element binding(GO:0032810)
0.1 3.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 2.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 3.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.6 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026) glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.8 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 1.9 GO:0004568 chitinase activity(GO:0004568)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.4 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.3 GO:0072545 tyrosine binding(GO:0072545)
0.1 5.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.3 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 6.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.7 GO:0034711 activin receptor activity, type I(GO:0016361) inhibin binding(GO:0034711)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 17.5 GO:0003823 antigen binding(GO:0003823)
0.1 0.2 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 4.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 1.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.6 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.9 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 2.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0019239 deaminase activity(GO:0019239)
0.0 3.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 3.3 GO:0008201 heparin binding(GO:0008201)
0.0 1.0 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.7 GO:0020037 heme binding(GO:0020037)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.7 GO:0033613 activating transcription factor binding(GO:0033613)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 1.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 5.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 3.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 3.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.0 ST ADRENERGIC Adrenergic Pathway
0.0 1.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 2.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 5.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 3.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 3.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 4.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 4.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 3.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 3.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 3.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 3.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 1.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins