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Illumina Body Map 2 (GSE30611)

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Results for TGIF1

Z-value: 0.97

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.22 TGFB induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg38_v1_chr18_+_3450036_3450212-0.577.4e-04Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_11847772 6.31 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr1_-_11848345 4.21 ENST00000376476.1
natriuretic peptide A
chr2_+_88067818 2.85 ENST00000444564.2
ENST00000419482.7
SET and MYND domain containing 1
chr2_-_171894227 2.69 ENST00000422440.7
solute carrier family 25 member 12
chr14_-_23435652 2.28 ENST00000355349.4
myosin heavy chain 7
chr2_+_88067849 2.20 ENST00000438570.1
SET and MYND domain containing 1
chr2_-_179049986 2.16 ENST00000409284.1
ENST00000443758.6
ENST00000446116.5
coiled-coil domain containing 141
chr19_-_45322867 2.11 ENST00000221476.4
creatine kinase, M-type
chr13_+_29428603 1.99 ENST00000380808.6
microtubule associated scaffold protein 2
chr22_-_35617321 1.96 ENST00000397326.7
ENST00000442617.1
myoglobin
chr13_+_29428709 1.87 ENST00000542829.1
microtubule associated scaffold protein 2
chr7_+_95772506 1.83 ENST00000537881.5
ENST00000447467.6
ENST00000524053.5
ENST00000324972.10
ENST00000630942.2
ENST00000437599.5
ENST00000359388.8
ENST00000413338.5
dynein cytoplasmic 1 intermediate chain 1
chr1_-_16018005 1.82 ENST00000406363.2
ENST00000411503.5
ENST00000311890.14
ENST00000487046.1
heat shock protein family B (small) member 7
chr6_+_41053194 1.60 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr13_+_75839716 1.43 ENST00000533809.2
LIM domain 7
chr1_-_16017825 1.33 ENST00000463576.5
heat shock protein family B (small) member 7
chr1_+_205504592 1.33 ENST00000506784.5
ENST00000360066.6
cyclin dependent kinase 18
chr2_-_71227055 1.25 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr1_+_74235377 1.23 ENST00000326637.8
TNNI3 interacting kinase
chr11_-_111910888 1.19 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr18_-_74457944 1.16 ENST00000400291.2
divergent protein kinase domain 1C
chr8_-_41665261 1.15 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ankyrin 1
chr11_-_111910830 1.15 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr2_+_27282419 1.13 ENST00000380075.7
ENST00000296098.4
tripartite motif containing 54
chr19_-_36152427 1.11 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chr6_+_25652201 1.09 ENST00000612225.4
ENST00000377961.3
secretagogin, EF-hand calcium binding protein
chr8_-_106770235 1.05 ENST00000311955.4
actin binding Rho activating protein
chr4_-_88284553 1.03 ENST00000608933.6
ENST00000295908.11
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr2_+_201071984 1.03 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr4_+_113116676 1.02 ENST00000671971.1
ENST00000672240.1
ENST00000673240.1
ENST00000673363.1
ankyrin 2
chr15_+_36594868 1.01 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDAN1 interacting nuclease 1
chr17_+_70169516 1.00 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr5_+_141969074 0.98 ENST00000506938.5
ENST00000394520.7
ENST00000394514.6
ENST00000512565.5
ring finger protein 14
chr1_+_99646025 0.96 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr1_+_205504644 0.95 ENST00000429964.7
ENST00000443813.6
cyclin dependent kinase 18
chr4_-_88284616 0.94 ENST00000508256.5
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr3_-_52685531 0.93 ENST00000439181.5
ENST00000449505.5
polybromo 1
chrM_+_5824 0.92 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr6_-_33746848 0.92 ENST00000634274.1
ENST00000293756.5
ENST00000451316.6
inositol hexakisphosphate kinase 3
chr14_+_99684283 0.87 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr11_-_111923722 0.84 ENST00000527950.5
crystallin alpha B
chr10_+_18340821 0.84 ENST00000612743.1
ENST00000612134.4
calcium voltage-gated channel auxiliary subunit beta 2
chr4_+_42397473 0.83 ENST00000319234.5
shisa family member 3
chr4_-_88284590 0.83 ENST00000510548.6
protein phosphatase, Mg2+/Mn2+ dependent 1K
chrX_-_103832204 0.81 ENST00000674363.1
ENST00000674162.1
ENST00000674338.1
ENST00000674274.1
ENST00000674271.1
ENST00000674265.1
ENST00000674212.1
ENST00000674255.1
ENST00000674342.1
ENST00000674430.1
ENST00000243298.3
novel transcript
RAB9B, member RAS oncogene family
chr1_-_151146611 0.79 ENST00000341697.7
ENST00000368914.8
semaphorin 6C
chr19_-_46661132 0.77 ENST00000410105.2
ENST00000391916.7
dishevelled binding antagonist of beta catenin 3
chr4_+_87975667 0.77 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr5_+_141969156 0.74 ENST00000507163.5
ring finger protein 14
chr1_-_217076889 0.74 ENST00000493748.5
ENST00000463665.5
estrogen related receptor gamma
chr2_+_33436304 0.74 ENST00000402538.7
RAS guanyl releasing protein 3
chr4_-_88284747 0.73 ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr5_+_141969190 0.72 ENST00000506004.5
ENST00000507291.1
ring finger protein 14
chr20_+_1266263 0.71 ENST00000649598.1
ENST00000381867.6
ENST00000381873.7
syntaphilin
chr8_-_41665200 0.71 ENST00000335651.6
ankyrin 1
chr4_+_127965429 0.71 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr5_+_145937793 0.70 ENST00000511217.1
SH3 domain containing ring finger 2
chr17_+_35147807 0.70 ENST00000394570.7
ENST00000268876.9
unc-45 myosin chaperone B
chr18_+_34976928 0.70 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr10_-_96357155 0.70 ENST00000536387.5
oligodendrocytic myelin paranodal and inner loop protein
chr4_+_127965267 0.69 ENST00000398965.5
abhydrolase domain containing 18
chr14_-_72894091 0.69 ENST00000556509.6
double PHD fingers 3
chr8_-_20303955 0.69 ENST00000381569.5
leucine zipper tumor suppressor 1
chrX_-_129654946 0.69 ENST00000429967.3
apelin
chr4_+_127965361 0.69 ENST00000444616.5
abhydrolase domain containing 18
chr4_+_127965394 0.69 ENST00000645843.2
ENST00000388795.9
abhydrolase domain containing 18
chr11_-_2301859 0.69 ENST00000456145.2
ENST00000381153.8
chromosome 11 open reading frame 21
chr4_+_87975829 0.68 ENST00000614857.5
secreted phosphoprotein 1
chr11_-_101129806 0.68 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr7_-_137343688 0.67 ENST00000348225.7
pleiotrophin
chr2_+_33134620 0.67 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr18_+_34493289 0.67 ENST00000682923.1
ENST00000596745.5
ENST00000283365.14
ENST00000315456.10
ENST00000598774.6
ENST00000684266.1
ENST00000683092.1
ENST00000683379.1
ENST00000684359.1
dystrobrevin alpha
chr9_+_131289685 0.66 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr10_+_68988767 0.65 ENST00000626493.2
ENST00000638119.2
ENST00000674936.1
ENST00000674660.1
ENST00000675576.1
ENST00000361983.7
ENST00000635971.2
kinesin family binding protein
chr22_+_23772839 0.65 ENST00000215743.8
matrix metallopeptidase 11
chr7_-_137343752 0.65 ENST00000393083.2
pleiotrophin
chr1_-_151146643 0.65 ENST00000613223.1
semaphorin 6C
chr6_-_118710065 0.63 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chr5_+_43192216 0.62 ENST00000326035.6
NIM1 serine/threonine protein kinase
chr9_+_2622053 0.61 ENST00000681306.1
ENST00000681618.1
very low density lipoprotein receptor
chr1_+_245154963 0.61 ENST00000407071.7
kinesin family member 26B
chr5_-_36301883 0.60 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr1_-_230714112 0.60 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
angiotensinogen
chr18_+_34493904 0.59 ENST00000680366.1
ENST00000684560.1
dystrobrevin alpha
chr8_-_73582830 0.59 ENST00000523533.5
staufen double-stranded RNA binding protein 2
chr2_+_33134579 0.59 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr2_-_217905445 0.59 ENST00000413554.5
tensin 1
chr2_+_33134406 0.58 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr4_+_113145608 0.58 ENST00000511380.1
ankyrin 2
chr12_-_54584302 0.58 ENST00000553113.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr4_-_46389351 0.58 ENST00000503806.5
ENST00000356504.5
ENST00000514090.5
ENST00000506961.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr7_+_30911845 0.57 ENST00000652696.1
ENST00000311813.11
aquaporin 1 (Colton blood group)
chr4_-_46389550 0.57 ENST00000507460.1
gamma-aminobutyric acid type A receptor subunit alpha2
chr1_-_160070150 0.56 ENST00000644903.1
potassium inwardly rectifying channel subfamily J member 10
chr5_-_128538230 0.55 ENST00000262464.9
fibrillin 2
chr5_+_141489150 0.55 ENST00000610789.1
protocadherin gamma subfamily C, 5
chr3_+_119294337 0.55 ENST00000264245.9
Rho GTPase activating protein 31
chr6_-_13487593 0.54 ENST00000379287.4
ENST00000603223.1
glucose-fructose oxidoreductase domain containing 1
chr6_+_101181254 0.54 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr14_-_95516616 0.54 ENST00000682763.1
spectrin repeat containing nuclear envelope family member 3
chr3_+_66998297 0.54 ENST00000484414.5
ENST00000460576.5
ENST00000417314.2
kelch repeat and BTB domain containing 8
chr3_+_69739425 0.53 ENST00000352241.9
ENST00000642352.1
melanocyte inducing transcription factor
chr3_-_39192584 0.53 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr1_+_6555301 0.53 ENST00000333172.11
ENST00000351136.7
taste 1 receptor member 1
chr11_+_111977300 0.52 ENST00000615255.1
DIX domain containing 1
chr4_-_113761563 0.52 ENST00000394522.7
calcium/calmodulin dependent protein kinase II delta
chr1_+_52726441 0.52 ENST00000294353.7
ENST00000545132.5
zyg-11 family member B, cell cycle regulator
chr11_+_12110569 0.52 ENST00000683283.1
ENST00000256194.8
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr5_+_141968886 0.51 ENST00000347642.7
ring finger protein 14
chr6_-_83709019 0.50 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
synaptosome associated protein 91
chr10_+_58269132 0.50 ENST00000333926.6
CDGSH iron sulfur domain 1
chr9_-_127873462 0.50 ENST00000223836.10
adenylate kinase 1
chr1_+_150067820 0.49 ENST00000419023.3
ENST00000644526.1
vacuolar protein sorting 45 homolog
chr1_+_7784411 0.49 ENST00000613533.4
ENST00000614998.4
period circadian regulator 3
chr13_-_48001240 0.49 ENST00000434484.5
succinate-CoA ligase ADP-forming subunit beta
chr5_-_132777229 0.49 ENST00000378721.8
ENST00000378719.7
ENST00000378701.5
septin 8
chr12_-_75209701 0.48 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr6_+_25652272 0.48 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr6_-_138545685 0.48 ENST00000342260.9
NHS like 1
chr8_+_66127043 0.48 ENST00000276573.11
ENST00000350034.4
ENST00000315962.9
tripartite motif containing 55
chr1_+_150067668 0.48 ENST00000611412.4
ENST00000644510.2
ENST00000643611.1
vacuolar protein sorting 45 homolog
chr4_+_107989880 0.48 ENST00000309522.8
ENST00000403312.6
ENST00000638559.1
ENST00000682373.1
hydroxyacyl-CoA dehydrogenase
chr2_+_172860038 0.48 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr12_-_75209814 0.47 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chr1_+_150067279 0.47 ENST00000643970.1
ENST00000535106.5
ENST00000369128.9
vacuolar protein sorting 45 homolog
chr8_-_81483226 0.47 ENST00000256104.5
fatty acid binding protein 4
chr8_-_74321532 0.47 ENST00000342232.5
junctophilin 1
chr14_-_105168753 0.47 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr21_-_34615103 0.47 ENST00000313806.9
regulator of calcineurin 1
chr4_-_113761724 0.46 ENST00000511664.6
calcium/calmodulin dependent protein kinase II delta
chr8_-_123396412 0.46 ENST00000287394.10
ATPase family AAA domain containing 2
chr4_+_158672237 0.46 ENST00000682734.1
electron transfer flavoprotein dehydrogenase
chr18_+_34493876 0.46 ENST00000590412.5
dystrobrevin alpha
chr16_-_53503192 0.46 ENST00000568596.5
ENST00000394657.12
ENST00000570004.5
ENST00000564497.1
ENST00000300245.8
AKT interacting protein
chr1_+_19484398 0.46 ENST00000648702.1
mitochondrial contact site and cristae organizing system subunit 10
chr19_-_49362376 0.45 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEA domain transcription factor 2
chr3_-_52685794 0.45 ENST00000424867.1
ENST00000394830.7
ENST00000431678.5
ENST00000450271.5
polybromo 1
chr20_+_36214373 0.45 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chrX_-_32412220 0.44 ENST00000619831.5
dystrophin
chr12_+_25195230 0.44 ENST00000381356.9
electron transfer flavoprotein regulatory factor 1
chr12_+_25195205 0.44 ENST00000557540.7
electron transfer flavoprotein regulatory factor 1
chr20_-_9839026 0.43 ENST00000378429.3
ENST00000353224.10
p21 (RAC1) activated kinase 5
chr3_-_33645433 0.43 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr1_-_160070102 0.43 ENST00000638728.1
ENST00000637644.1
potassium inwardly rectifying channel subfamily J member 10
chr1_+_26021768 0.43 ENST00000374280.4
exostosin like glycosyltransferase 1
chr18_+_34493386 0.43 ENST00000679936.1
dystrobrevin alpha
chr4_-_82561972 0.43 ENST00000454948.3
ENST00000449862.7
transmembrane protein 150C
chr10_-_14330879 0.43 ENST00000357447.7
FERM domain containing 4A
chr2_-_37084302 0.42 ENST00000233099.6
HEAT repeat containing 5B
chr18_-_24311495 0.42 ENST00000357041.8
oxysterol binding protein like 1A
chr12_+_25195252 0.42 ENST00000555711.6
ENST00000554266.6
ENST00000556351.6
ENST00000556927.6
ENST00000556402.6
ENST00000553788.6
electron transfer flavoprotein regulatory factor 1
chr10_+_68109433 0.42 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr1_+_39409327 0.41 ENST00000530275.3
microtubule actin crosslinking factor 1
chr18_+_34493428 0.41 ENST00000682483.1
dystrobrevin alpha
chr18_+_56651661 0.41 ENST00000593058.1
WD repeat domain 7
chr1_-_38941796 0.41 ENST00000540558.1
ENST00000372990.6
rhomboid like 2
chr4_+_107989714 0.41 ENST00000505878.4
ENST00000603302.5
ENST00000638621.1
hydroxyacyl-CoA dehydrogenase
chrX_+_41689006 0.41 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr2_+_57907621 0.40 ENST00000648897.1
ENST00000435505.6
ENST00000417641.6
VRK serine/threonine kinase 2
chr3_-_180989518 0.40 ENST00000479269.5
ENST00000646965.1
DnaJ heat shock protein family (Hsp40) member C19
chr8_+_141416141 0.40 ENST00000680615.1
protein tyrosine phosphatase 4A3
chr17_+_44846318 0.39 ENST00000591513.5
HIG1 hypoxia inducible domain family member 1B
chr3_-_33645253 0.39 ENST00000333778.10
cytoplasmic linker associated protein 2
chr5_-_132777215 0.39 ENST00000458488.2
septin 8
chr1_+_103561757 0.39 ENST00000435302.5
amylase alpha 2B
chr20_+_4686320 0.39 ENST00000430350.2
prion protein
chr8_+_141416078 0.39 ENST00000349124.3
protein tyrosine phosphatase 4A3
chr5_-_132777404 0.39 ENST00000296873.11
septin 8
chrX_+_41688967 0.39 ENST00000378142.9
G protein-coupled receptor 34
chr1_-_156282799 0.39 ENST00000361813.5
SMG5 nonsense mediated mRNA decay factor
chr5_-_132777344 0.38 ENST00000378706.5
septin 8
chr4_+_168711416 0.38 ENST00000649826.1
palladin, cytoskeletal associated protein
chr12_+_65279445 0.38 ENST00000642404.1
methionine sulfoxide reductase B3
chr18_+_56651335 0.38 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr1_+_163068775 0.38 ENST00000421743.6
regulator of G protein signaling 4
chr17_+_17042505 0.38 ENST00000577514.5
myosin phosphatase Rho interacting protein
chr19_-_14117729 0.38 ENST00000590853.5
ENST00000308677.9
protein kinase cAMP-activated catalytic subunit alpha
chr11_-_6405405 0.38 ENST00000608645.5
ENST00000618005.4
ENST00000610474.4
ENST00000608394.5
ENST00000529519.5
amyloid beta precursor protein binding family B member 1
chr3_-_52685896 0.38 ENST00000420148.5
polybromo 1
chr8_+_30638562 0.38 ENST00000517349.2
small integral membrane protein 18
chr6_-_83709141 0.37 ENST00000521743.5
synaptosome associated protein 91
chr1_+_36156096 0.37 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr10_+_84245038 0.37 ENST00000650682.1
ENST00000358110.7
ENST00000651237.1
ENST00000652122.1
ENST00000652092.2
ENST00000359452.9
ENST00000483744.6
retinal G protein coupled receptor
chr17_-_59155164 0.37 ENST00000583380.5
ENST00000580541.1
ENST00000578105.1
ENST00000330137.12
ENST00000437036.6
spindle and kinetochore associated complex subunit 2
chr4_-_113761441 0.36 ENST00000394524.7
calcium/calmodulin dependent protein kinase II delta
chr1_-_204359885 0.36 ENST00000414478.1
ENST00000272203.8
pleckstrin homology domain containing A6
chr3_-_180989678 0.36 ENST00000491873.5
ENST00000382564.8
ENST00000486355.1
DnaJ heat shock protein family (Hsp40) member C19
chr12_-_75209422 0.36 ENST00000393288.2
ENST00000540018.5
potassium voltage-gated channel subfamily C member 2
chr10_-_73495966 0.36 ENST00000342558.3
ENST00000360663.10
ENST00000394828.6
ENST00000394829.6
protein phosphatase 3 catalytic subunit beta
chr9_+_131289807 0.35 ENST00000372261.1
phospholipid phosphatase 7 (inactive)
chr4_-_108762535 0.35 ENST00000512320.1
ENST00000510723.1
ethanolamine-phosphate phospho-lyase
chr8_+_66126896 0.34 ENST00000353317.9
tripartite motif containing 55
chr9_-_127874964 0.34 ENST00000373156.5
adenylate kinase 1
chr10_+_123008966 0.34 ENST00000368869.8
ENST00000358776.7
acyl-CoA dehydrogenase short/branched chain
chr2_+_223051814 0.34 ENST00000281830.3
potassium voltage-gated channel subfamily E regulatory subunit 4
chr17_+_4948252 0.34 ENST00000520221.5
enolase 3
chr10_-_97633485 0.34 ENST00000370635.3
ENST00000478953.1
ENST00000307450.11
MORN repeat containing 4
chr11_-_61580826 0.34 ENST00000540677.5
ENST00000542836.5
ENST00000542670.5
ENST00000535826.5
ENST00000545053.1
ENST00000539008.6
synaptotagmin 7
chr20_+_4686448 0.33 ENST00000379440.9
ENST00000424424.2
ENST00000457586.2
prion protein
chr1_+_240014319 0.33 ENST00000447095.5
formin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.5 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.9 2.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.6 2.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.5 1.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.4 1.3 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.3 1.3 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3 2.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 1.5 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 2.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.7 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.2 0.6 GO:0014873 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.2 0.6 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 1.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 0.7 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.5 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.2 0.5 GO:0019417 sulfur oxidation(GO:0019417)
0.2 1.8 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 2.0 GO:0036309 protein localization to M-band(GO:0036309)
0.1 1.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 1.6 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 3.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 2.1 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.5 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.5 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 1.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 5.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 3.9 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 0.3 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.3 GO:0090273 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.1 1.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.3 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 1.9 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.2 GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
0.1 0.6 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.6 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 1.5 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 0.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.2 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.2 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 1.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.8 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 2.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.7 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.1 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.0 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 2.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 1.6 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 1.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.9 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 1.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.5 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) organ senescence(GO:0010260) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 1.0 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.4 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 2.8 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0042262 DNA protection(GO:0042262)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.7 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.5 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.5 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.0 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.5 GO:0042629 mast cell granule(GO:0042629)
0.2 0.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.2 3.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 0.3 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.2 GO:0005715 late recombination nodule(GO:0005715)
0.1 1.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 3.4 GO:0016235 aggresome(GO:0016235)
0.0 2.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 3.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 4.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.0 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 4.3 GO:0042383 sarcolemma(GO:0042383)
0.0 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 1.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 11.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 1.6 GO:0050436 microfibril binding(GO:0050436)
0.3 2.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.6 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 1.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 0.5 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.6 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.7 GO:1903135 cupric ion binding(GO:1903135)
0.1 1.2 GO:0031013 troponin I binding(GO:0031013)
0.1 1.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.6 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.5 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 3.2 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 2.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 2.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.2 GO:0036332 VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.9 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 4.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 3.5 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 2.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 1.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 3.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 2.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 2.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 5.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.0 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 3.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 2.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors