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Illumina Body Map 2 (GSE30611)

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Results for THRA_RXRB

Z-value: 1.75

Motif logo

Transcription factors associated with THRA_RXRB

Gene Symbol Gene ID Gene Info
ENSG00000126351.13 thyroid hormone receptor alpha
ENSG00000204231.11 retinoid X receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RXRBhg38_v1_chr6_-_33200614_332006800.222.4e-01Click!
THRAhg38_v1_chr17_+_40062956_40062978-0.154.3e-01Click!

Activity profile of THRA_RXRB motif

Sorted Z-values of THRA_RXRB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_22922594 15.15 ENST00000390331.3
immunoglobulin lambda constant 7
chr14_-_105708627 10.56 ENST00000641837.1
ENST00000390547.3
immunoglobulin heavy constant alpha 1
chr14_-_105588322 9.19 ENST00000497872.4
ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_22792485 8.59 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr1_-_150720842 8.30 ENST00000442853.5
ENST00000368995.8
ENST00000322343.11
ENST00000361824.7
HORMA domain containing 1
chr22_+_22758698 8.24 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr22_+_22409755 7.94 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr22_+_22822658 6.51 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr22_+_22734577 5.71 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr1_+_178513103 5.03 ENST00000319416.7
ENST00000367643.7
ENST00000367642.3
ENST00000367641.7
ENST00000367639.1
testis expressed 35
chr22_+_22900976 4.93 ENST00000390323.2
immunoglobulin lambda constant 2
chr22_+_22431949 4.79 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr22_+_22668286 4.46 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr22_+_22098683 4.41 ENST00000390283.2
immunoglobulin lambda variable 8-61
chr16_+_85908988 4.27 ENST00000566369.1
interferon regulatory factor 8
chr1_-_150720829 4.24 ENST00000368987.5
HORMA domain containing 1
chr22_+_22327298 4.20 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr22_-_28741783 3.83 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr7_+_100589573 3.72 ENST00000468962.5
ENST00000427939.2
F-box protein 24
chr19_-_39335999 3.71 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr22_+_22195753 3.71 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr1_+_32362537 3.42 ENST00000373534.4
testis specific serine kinase 3
chr5_+_40679907 3.39 ENST00000302472.4
prostaglandin E receptor 4
chr1_-_32362081 3.38 ENST00000432622.1
family with sequence similarity 229 member A
chr7_+_128791968 3.19 ENST00000297788.9
ENST00000487361.5
coiled-coil domain containing 136
chr12_-_52601458 3.13 ENST00000537672.6
ENST00000293745.7
keratin 72
chr22_+_22162155 3.06 ENST00000390284.2
immunoglobulin lambda variable 4-60
chr11_-_123885627 2.96 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr3_+_10026409 2.95 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr22_+_22343185 2.90 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr20_-_13990609 2.87 ENST00000284951.10
ENST00000378072.5
SEL1L2 adaptor subunit of ERAD E3 ligase
chr14_-_23567734 2.85 ENST00000556843.1
ENST00000397120.8
ENST00000557189.5
adaptor related protein complex 1 subunit gamma 2
chr19_+_49335396 2.80 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chrX_-_71106728 2.76 ENST00000374251.6
chromosome X open reading frame 65
chr22_+_22357739 2.71 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr5_+_163460623 2.66 ENST00000393915.9
ENST00000432118.6
hyaluronan mediated motility receptor
chr14_-_24609660 2.44 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
granzyme H
chr16_-_50681289 2.43 ENST00000423026.6
ENST00000330943.9
sorting nexin 20
chr20_+_44715360 2.40 ENST00000190983.5
cellular communication network factor 5
chr19_-_55363243 2.33 ENST00000424985.3
family with sequence similarity 71 member E2
chr16_-_11273610 2.31 ENST00000327157.4
protamine 3
chr16_-_58295019 2.29 ENST00000567164.6
ENST00000219301.8
ENST00000569727.1
serine protease 54
chr19_+_48606732 2.11 ENST00000321762.3
sperm acrosome associated 4
chr2_+_218880844 2.11 ENST00000258411.8
Wnt family member 10A
chr19_+_16076485 2.06 ENST00000643579.2
ENST00000646575.1
tropomyosin 4
chrX_-_30309387 2.05 ENST00000378970.5
nuclear receptor subfamily 0 group B member 1
chr8_+_102551583 1.98 ENST00000285402.4
outer dense fiber of sperm tails 1
chr9_-_124595808 1.96 ENST00000475178.1
nuclear receptor subfamily 6 group A member 1
chr1_-_159925496 1.87 ENST00000368097.9
transgelin 2
chr11_-_5509929 1.84 ENST00000311659.5
ENST00000445998.1
ubiquilin 3
chr16_-_58294976 1.83 ENST00000543437.5
ENST00000569079.1
serine protease 54
chr4_+_89901979 1.83 ENST00000508372.1
multimerin 1
chr12_-_52601507 1.79 ENST00000354310.4
keratin 72
chr2_+_231592858 1.78 ENST00000313965.4
testis expressed 44
chr1_+_160177386 1.77 ENST00000470705.1
ATPase Na+/K+ transporting subunit alpha 4
chr6_+_21593742 1.74 ENST00000244745.4
SRY-box transcription factor 4
chr3_+_45026296 1.73 ENST00000296130.5
C-type lectin domain family 3 member B
chr19_+_53867874 1.72 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
myeloid associated differentiation marker
chr8_-_141507230 1.71 ENST00000621837.1
maestro heat like repeat family member 5 (gene/pseudogene)
chr16_-_29745951 1.70 ENST00000329410.4
chromosome 16 open reading frame 54
chr1_+_212624472 1.69 ENST00000294829.5
family with sequence similarity 71 member A
chr6_+_139135063 1.69 ENST00000367658.3
hdc homolog, cell cycle regulator
chr14_-_105601728 1.69 ENST00000641420.1
ENST00000390541.2
immunoglobulin heavy constant epsilon
chr14_+_22052503 1.68 ENST00000390449.3
T cell receptor alpha variable 21
chr9_+_136980211 1.67 ENST00000444903.2
prostaglandin D2 synthase
chr13_-_46182136 1.66 ENST00000323076.7
lymphocyte cytosolic protein 1
chr2_+_55232359 1.65 ENST00000449323.5
ribosomal protein S27a
chr17_+_6996042 1.65 ENST00000251535.11
arachidonate 12-lipoxygenase, 12S type
chr22_+_22214765 1.63 ENST00000390287.2
immunoglobulin lambda variable 10-54
chr11_-_26572130 1.61 ENST00000527569.1
mucin 15, cell surface associated
chr20_+_33662310 1.61 ENST00000375222.4
chromosome 20 open reading frame 144
chr2_+_55232672 1.61 ENST00000404735.1
ENST00000272317.11
ribosomal protein S27a
chr20_+_38962299 1.60 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr11_+_122838492 1.58 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr16_-_72172135 1.57 ENST00000537465.5
ENST00000237353.15
polyamine modulated factor 1 binding protein 1
chr20_-_33004307 1.53 ENST00000420875.5
ENST00000375519.2
ENST00000375523.7
ENST00000356173.8
Sad1 and UNC84 domain containing 5
chr2_-_191151568 1.52 ENST00000358470.8
ENST00000432798.1
ENST00000450994.1
signal transducer and activator of transcription 4
chr15_-_34337462 1.51 ENST00000676379.1
solute carrier family 12 member 6
chr15_-_34338033 1.51 ENST00000558667.5
ENST00000561120.5
ENST00000559236.5
ENST00000397702.6
solute carrier family 12 member 6
chr6_-_88963573 1.48 ENST00000369485.9
RNA guanylyltransferase and 5'-phosphatase
chr9_+_36572854 1.39 ENST00000543751.5
ENST00000536860.5
ENST00000541717.4
ENST00000536329.5
ENST00000536987.5
ENST00000298048.7
ENST00000495529.5
ENST00000545008.5
maternal embryonic leucine zipper kinase
chr1_+_44746401 1.37 ENST00000372217.5
kinesin family member 2C
chr7_+_128672275 1.36 ENST00000684498.1
ENST00000641605.1
ENST00000682356.1
ENST00000477515.3
family with sequence similarity 71 member F2
chr15_+_45129933 1.35 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr11_+_64340191 1.33 ENST00000356786.10
coiled-coil domain containing 88B
chr8_-_130016395 1.32 ENST00000523509.5
CYFIP related Rac1 interactor B
chr5_-_150449676 1.30 ENST00000312037.6
ribosomal protein S14
chr19_+_40611863 1.29 ENST00000601032.5
latent transforming growth factor beta binding protein 4
chr7_+_128791390 1.29 ENST00000459946.5
ENST00000378685.8
ENST00000464832.5
ENST00000472049.1
ENST00000488925.1
coiled-coil domain containing 136
chr1_-_149927756 1.27 ENST00000271628.9
splicing factor 3b subunit 4
chr5_-_150449731 1.27 ENST00000407193.7
ribosomal protein S14
chr12_-_114406133 1.26 ENST00000405440.7
T-box transcription factor 5
chr2_+_230996115 1.25 ENST00000424440.5
ENST00000452881.5
ENST00000433428.6
ENST00000455816.1
ENST00000440792.5
ENST00000423134.1
spermatogenesis associated 3
chr20_+_3796288 1.25 ENST00000439880.6
ENST00000245960.10
cell division cycle 25B
chr19_-_10339610 1.25 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr9_+_35042213 1.23 ENST00000378745.3
ENST00000312292.6
chromosome 9 open reading frame 131
chrX_+_13569593 1.21 ENST00000361306.6
ENST00000380602.3
EGF like domain multiple 6
chr17_+_60422483 1.21 ENST00000269127.5
chromosome 17 open reading frame 64
chr8_-_130016536 1.19 ENST00000519020.5
CYFIP related Rac1 interactor B
chr8_+_85987287 1.19 ENST00000521564.1
ATPase H+ transporting V0 subunit d2
chr5_-_132866884 1.18 ENST00000624492.3
ENST00000621295.4
growth differentiation factor 9
chr12_+_102120172 1.18 ENST00000327680.7
ENST00000541394.5
ENST00000543784.5
PARP1 binding protein
chr22_-_37188281 1.16 ENST00000397110.6
C1q and TNF related 6
chr19_-_51065067 1.16 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
kallikrein related peptidase 13
chr9_-_86259604 1.16 ENST00000376001.7
ENST00000339137.7
chromosome 9 open reading frame 153
chr22_+_50738198 1.16 ENST00000216139.10
ENST00000529621.1
acrosin
chr1_-_175192911 1.15 ENST00000444639.5
KIAA0040
chr21_-_31558977 1.15 ENST00000286827.7
ENST00000541036.5
TIAM Rac1 associated GEF 1
chr16_+_67666770 1.14 ENST00000403458.9
ENST00000602365.1
chromosome 16 open reading frame 86
chr1_+_54641806 1.14 ENST00000409996.5
maestro heat like repeat family member 7
chr15_-_34337719 1.12 ENST00000559484.1
ENST00000558589.5
ENST00000458406.6
solute carrier family 12 member 6
chr8_-_130016622 1.11 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr14_-_76826229 1.09 ENST00000557497.1
angel homolog 1
chr3_-_126558926 1.09 ENST00000318225.3
chromosome 3 open reading frame 22
chr16_-_1884231 1.09 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr10_+_100998676 1.08 ENST00000481129.1
leucine zipper tumor suppressor 2
chr3_-_179604648 1.08 ENST00000392659.2
mitochondrial ribosomal protein L47
chr11_-_58575846 1.07 ENST00000395074.7
leupaxin
chr1_+_20070156 1.05 ENST00000375108.4
phospholipase A2 group V
chr16_+_31355215 1.05 ENST00000562522.2
integrin subunit alpha X
chr14_-_58427114 1.04 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr1_+_54641754 1.04 ENST00000339553.9
ENST00000421030.7
maestro heat like repeat family member 7
chr18_+_63476927 1.01 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr19_-_35228699 1.01 ENST00000324675.3
family with sequence similarity 187 member B
chr16_-_57536543 1.01 ENST00000258214.3
coiled-coil domain containing 102A
chr22_+_22871478 1.01 ENST00000390318.2
immunoglobulin lambda variable 4-3
chr5_+_136058849 1.00 ENST00000508076.5
transforming growth factor beta induced
chr21_+_43719095 0.99 ENST00000468090.5
ENST00000291565.9
pyridoxal kinase
chr6_-_31815244 0.98 ENST00000375654.5
heat shock protein family A (Hsp70) member 1 like
chr13_-_75537805 0.97 ENST00000626103.1
ENST00000682242.1
ENST00000355801.4
COMM domain containing 6
chr16_+_4734519 0.96 ENST00000299320.10
chromosome 16 open reading frame 71
chr1_+_196652022 0.95 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
complement factor H
chr16_+_4734278 0.95 ENST00000586724.5
chromosome 16 open reading frame 71
chr14_+_88385643 0.95 ENST00000393545.9
ENST00000356583.9
ENST00000555401.5
ENST00000553885.5
spermatogenesis associated 7
chr1_+_154327737 0.95 ENST00000672630.1
ATPase phospholipid transporting 8B2
chr14_-_58427134 0.94 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr17_+_45844875 0.94 ENST00000329196.7
signal peptide peptidase like 2C
chr6_+_31815532 0.94 ENST00000375651.7
ENST00000608703.1
heat shock protein family A (Hsp70) member 1A
chr1_+_54641816 0.94 ENST00000395690.6
maestro heat like repeat family member 7
chr16_-_50681206 0.92 ENST00000610485.1
sorting nexin 20
chr19_+_49363074 0.91 ENST00000597873.5
dickkopf like acrosomal protein 1
chr7_+_23710203 0.91 ENST00000422637.5
ENST00000355870.8
serine/threonine kinase 31
chr15_+_43791842 0.91 ENST00000674451.1
ENST00000630046.2
small EDRK-rich factor 2
chr9_+_113536497 0.91 ENST00000462143.5
regulator of G protein signaling 3
chr22_-_37188233 0.90 ENST00000434784.1
ENST00000337843.7
C1q and TNF related 6
chr7_-_37448845 0.90 ENST00000310758.9
engulfment and cell motility 1
chr15_+_78266181 0.89 ENST00000446172.2
DnaJ heat shock protein family (Hsp40) member A4
chr12_-_121580954 0.89 ENST00000536437.5
ENST00000611216.4
ENST00000538046.6
ENST00000377071.9
lysine demethylase 2B
chr3_-_183555696 0.89 ENST00000341319.8
kelch like family member 6
chr7_+_23710326 0.88 ENST00000354639.7
ENST00000531170.5
ENST00000444333.2
serine/threonine kinase 31
chr1_-_7853054 0.88 ENST00000361696.10
urotensin 2
chr14_-_103562257 0.88 ENST00000337322.4
ENST00000445922.2
BAG cochaperone 5
chr9_+_137251261 0.88 ENST00000620243.4
ENST00000388931.7
ENST00000412566.5
ENST00000611378.4
sperm-tail PG-rich repeat containing 3
chr5_-_177554545 0.87 ENST00000514747.6
family with sequence similarity 193 member B
chr15_+_74619089 0.87 ENST00000562670.5
ENST00000564096.1
CDC like kinase 3
chr8_-_144527006 0.87 ENST00000533758.1
ENST00000529415.7
leucine rich repeat containing 24
chr15_-_34337772 0.86 ENST00000354181.8
solute carrier family 12 member 6
chr14_-_54902807 0.85 ENST00000543643.6
ENST00000536224.2
ENST00000395514.5
ENST00000491895.7
GTP cyclohydrolase 1
chr2_-_229921963 0.84 ENST00000343290.5
ENST00000389044.8
ENST00000675453.1
ENST00000675903.1
ENST00000283943.9
thyroid hormone receptor interactor 12
chr7_+_23710263 0.84 ENST00000433467.6
serine/threonine kinase 31
chr5_-_150449696 0.83 ENST00000401695.8
ribosomal protein S14
chr17_+_62380553 0.83 ENST00000305286.8
ENST00000520404.5
ENST00000518576.1
EF-hand calcium binding domain 3
chrX_-_133753681 0.82 ENST00000406757.2
glypican 3
chr14_+_88385714 0.82 ENST00000045347.11
spermatogenesis associated 7
chr2_-_55232158 0.81 ENST00000407122.5
ENST00000401408.6
clathrin heavy chain linker domain containing 1
chr3_+_113532508 0.81 ENST00000264852.9
SID1 transmembrane family member 1
chr22_-_29388530 0.80 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
adaptor related protein complex 1 subunit beta 1
chr5_+_119629552 0.80 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chr16_+_4734457 0.80 ENST00000590191.1
chromosome 16 open reading frame 71
chr14_-_103562637 0.78 ENST00000299204.6
BAG cochaperone 5
chr7_+_5045821 0.78 ENST00000353796.7
ENST00000396912.2
ENST00000396904.2
RB associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr1_-_203175783 0.78 ENST00000621380.1
ENST00000255416.9
myosin binding protein H
chr2_+_196713117 0.78 ENST00000409270.5
coiled-coil domain containing 150
chr14_+_22883220 0.78 ENST00000536884.1
ENST00000267396.9
RRAD and GEM like GTPase 2
chr8_-_143331811 0.78 ENST00000522041.5
DNA topoisomerase I mitochondrial
chr8_+_144012273 0.77 ENST00000377470.8
spermatogenesis and centriole associated 1
chr2_+_74530018 0.77 ENST00000437202.1
HtrA serine peptidase 2
chr3_-_179604628 0.76 ENST00000476781.6
ENST00000259038.6
mitochondrial ribosomal protein L47
chr17_+_28744034 0.74 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr17_-_5234801 0.74 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr8_-_143568854 0.73 ENST00000524906.5
ENST00000532862.1
ENST00000534459.5
maestro heat like repeat family member 6
chr2_-_55232352 0.72 ENST00000451916.1
clathrin heavy chain linker domain containing 1
chr4_+_20253500 0.72 ENST00000622093.4
ENST00000273739.9
slit guidance ligand 2
chr3_-_79019444 0.72 ENST00000618833.4
ENST00000436010.6
ENST00000618846.4
roundabout guidance receptor 1
chr19_-_39738017 0.69 ENST00000221804.5
Charcot-Leyden crystal galectin
chr16_+_3024000 0.69 ENST00000326266.13
ENST00000574549.5
ENST00000575576.5
ENST00000253952.9
THO complex 6
chr17_-_46192767 0.69 ENST00000262419.10
KAT8 regulatory NSL complex subunit 1
chr10_+_100998348 0.68 ENST00000429732.5
leucine zipper tumor suppressor 2
chr15_+_43792305 0.68 ENST00000249786.9
ENST00000409960.6
ENST00000409646.5
ENST00000339624.9
ENST00000409291.5
ENST00000402131.5
ENST00000403425.5
ENST00000430901.1
small EDRK-rich factor 2
chr19_-_51026593 0.67 ENST00000600362.5
ENST00000453757.8
ENST00000601671.1
kallikrein related peptidase 11
chr7_+_77122609 0.66 ENST00000285871.5
coiled-coil domain containing 146
chr1_+_241652275 0.66 ENST00000366552.6
ENST00000437684.7
WD repeat domain 64
chr5_+_177303768 0.66 ENST00000303204.9
ENST00000503216.5
PRELI domain containing 1
chr17_+_28744002 0.66 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TNF receptor associated factor 4
chr7_+_121328991 0.66 ENST00000222462.3
Wnt family member 16
chr17_-_3691748 0.66 ENST00000552723.1
purinergic receptor P2X 5
chr22_-_16592810 0.66 ENST00000359963.4
chaperonin containing TCP1 subunit 8 like 2
chr14_-_58427158 0.65 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
translocase of inner mitochondrial membrane 9
chr3_-_15333152 0.65 ENST00000426925.5
SH3 domain binding protein 5
chr15_-_31101707 0.65 ENST00000397795.6
ENST00000256552.11
ENST00000559179.2
transient receptor potential cation channel subfamily M member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0051598 meiotic recombination checkpoint(GO:0051598)
1.8 19.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.3 3.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.1 3.4 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.7 5.0 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.6 1.8 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.4 1.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.4 1.7 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.4 3.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4 1.1 GO:1904268 positive regulation of Schwann cell migration(GO:1900149) regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.4 1.5 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.4 58.3 GO:0030449 regulation of complement activation(GO:0030449)
0.4 0.7 GO:0071623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.3 1.7 GO:0035905 N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 1.3 GO:0042335 cuticle development(GO:0042335)
0.3 1.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3 0.9 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.3 2.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 0.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.3 1.1 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.3 1.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 3.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 1.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.7 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.2 1.2 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.2 0.9 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 1.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 0.7 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 0.9 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 2.9 GO:0048733 sebaceous gland development(GO:0048733)
0.2 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 4.5 GO:0001675 acrosome assembly(GO:0001675)
0.2 5.6 GO:0042832 defense response to protozoan(GO:0042832)
0.2 1.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 0.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.2 1.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 3.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 1.8 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.4 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 2.3 GO:0007144 female meiosis I(GO:0007144)
0.1 0.7 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 2.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.7 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 1.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.4 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 27.5 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.6 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 2.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.5 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 3.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 2.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.8 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.1 0.7 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.3 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.7 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.2 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 2.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.9 GO:0002467 germinal center formation(GO:0002467)
0.1 0.5 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 1.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 2.3 GO:0042026 protein refolding(GO:0042026)
0.1 0.5 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 2.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 2.4 GO:0019835 cytolysis(GO:0019835)
0.1 0.4 GO:0046061 dATP catabolic process(GO:0046061)
0.0 1.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.9 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.8 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 1.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 5.8 GO:0070268 cornification(GO:0070268)
0.0 1.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 2.4 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.4 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.7 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 1.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 1.0 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0 0.3 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 2.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.7 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 4.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.4 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 0.3 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.4 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 1.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 1.8 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.9 GO:0001881 receptor recycling(GO:0001881)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.0 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.7 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.4 1.2 GO:0043159 acrosomal matrix(GO:0043159)
0.4 2.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.4 2.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 16.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 1.1 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.2 1.7 GO:0001652 granular component(GO:0001652)
0.2 12.5 GO:0000795 synaptonemal complex(GO:0000795)
0.2 0.9 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2 7.3 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.6 GO:0035841 new growing cell tip(GO:0035841)
0.1 2.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.0 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.1 2.3 GO:0000786 nucleosome(GO:0000786)
0.1 6.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.0 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 1.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.8 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 5.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.5 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 1.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 1.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 7.6 GO:0072562 blood microparticle(GO:0072562)
0.0 4.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 3.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 34.1 GO:0005615 extracellular space(GO:0005615)
0.0 3.6 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.8 GO:0016234 inclusion body(GO:0016234)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.5 36.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 1.7 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.4 1.5 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.3 3.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 1.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.3 70.2 GO:0003823 antigen binding(GO:0003823)
0.3 5.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 1.2 GO:0004040 amidase activity(GO:0004040)
0.3 0.8 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3 1.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.3 3.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 3.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.5 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.2 0.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 1.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.4 GO:0044713 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.1 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 2.1 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 3.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 1.4 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.1 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.7 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 1.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 1.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 6.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 1.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 5.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 2.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 1.1 GO:0004601 peroxidase activity(GO:0004601)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 3.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.9 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 PID ATM PATHWAY ATM pathway
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.9 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 10.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 4.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 2.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 3.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 3.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 5.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.8 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 3.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing