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Illumina Body Map 2 (GSE30611)

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Results for TP63

Z-value: 1.76

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Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
ENSG00000073282.14 tumor protein p63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg38_v1_chr3_+_189789672_1897896810.392.7e-02Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_119431846 5.64 ENST00000306406.5
transmembrane protein 37
chr1_-_153615858 4.38 ENST00000476873.5
S100 calcium binding protein A14
chr1_-_47190013 4.15 ENST00000294338.7
PDZK1 interacting protein 1
chr19_+_18386150 3.94 ENST00000252809.3
growth differentiation factor 15
chr6_-_46954922 3.92 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr7_+_80638510 3.82 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr11_+_18266254 3.74 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr10_-_88991282 3.61 ENST00000458159.5
ENST00000415557.1
actin alpha 2, smooth muscle
chr11_-_111911759 3.61 ENST00000650687.2
crystallin alpha B
chrX_+_2752024 3.52 ENST00000644266.2
ENST00000419513.7
ENST00000509484.3
ENST00000381174.10
Xg glycoprotein (Xg blood group)
chr13_-_77918820 3.51 ENST00000646607.2
endothelin receptor type B
chr2_+_216659600 3.36 ENST00000456764.1
insulin like growth factor binding protein 2
chr1_-_209651291 3.30 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr7_+_80638662 3.20 ENST00000394788.7
CD36 molecule
chr13_-_77918788 3.19 ENST00000626030.1
endothelin receptor type B
chr7_+_80638633 3.13 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr14_+_51489112 3.13 ENST00000356218.8
FERM domain containing 6
chr15_+_74174403 3.08 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine rich repeat
chr4_+_25648011 3.03 ENST00000645788.1
solute carrier family 34 member 2
chr2_-_150487658 2.92 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr12_+_119178920 2.89 ENST00000281938.7
heat shock protein family B (small) member 8
chr12_+_119178953 2.86 ENST00000674542.1
heat shock protein family B (small) member 8
chr15_+_40844018 2.86 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr6_+_121435595 2.82 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr19_-_4518465 2.81 ENST00000633942.1
perilipin 4
chr2_+_233691607 2.75 ENST00000373424.5
ENST00000441351.1
UDP glucuronosyltransferase family 1 member A6
chr9_+_35906179 2.75 ENST00000354323.3
histidine rich carboxyl terminus 1
chr6_-_42142604 2.73 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr15_-_88913362 2.71 ENST00000558029.5
ENST00000268150.13
ENST00000542878.5
ENST00000268151.11
ENST00000566497.5
milk fat globule EGF and factor V/VIII domain containing
chr20_-_54173976 2.64 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr1_-_12618198 2.58 ENST00000616661.5
dehydrogenase/reductase 3
chr10_-_86969178 2.57 ENST00000440490.1
ENST00000609457.5
ADIRF antisense RNA 1
multimerin 2
chr11_-_120138104 2.49 ENST00000341846.10
tripartite motif containing 29
chr11_+_76782250 2.48 ENST00000533752.1
ENST00000612930.1
tsukushi, small leucine rich proteoglycan
chr10_-_86969442 2.44 ENST00000474994.2
multimerin 2
chr2_-_164842011 2.40 ENST00000409184.8
ENST00000456693.5
cordon-bleu WH2 repeat protein like 1
chr11_+_111912725 2.30 ENST00000304298.4
heat shock protein family B (small) member 2
chr3_-_50303565 2.29 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
hyaluronidase 1
chr12_-_88580459 2.27 ENST00000552044.1
ENST00000644744.1
ENST00000357116.4
KIT ligand
chrX_-_154374623 2.23 ENST00000369850.10
filamin A
chr16_-_67190099 2.21 ENST00000314586.11
ENST00000563889.1
ENST00000564418.1
ENST00000545725.6
exocyst complex component 3 like 1
chr3_+_111911604 2.18 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr3_+_132597260 2.17 ENST00000249887.3
atypical chemokine receptor 4
chr2_-_164842140 2.16 ENST00000496396.1
ENST00000629362.2
ENST00000445474.2
ENST00000483743.6
cordon-bleu WH2 repeat protein like 1
chr19_-_5293232 2.15 ENST00000591760.5
protein tyrosine phosphatase receptor type S
chr19_-_17264718 2.14 ENST00000431146.6
ENST00000594190.5
USH1 protein network component harmonin binding protein 1
chr10_-_86957582 2.13 ENST00000372027.10
multimerin 2
chr1_-_79188467 2.10 ENST00000656300.1
adhesion G protein-coupled receptor L4
chr6_+_54846735 2.09 ENST00000306858.8
family with sequence similarity 83 member B
chr1_-_12616762 2.07 ENST00000464917.5
dehydrogenase/reductase 3
chr5_+_42423433 2.04 ENST00000230882.9
growth hormone receptor
chr11_+_27040725 2.03 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr12_-_6124662 2.01 ENST00000261405.10
von Willebrand factor
chr6_+_36676455 2.01 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr17_-_41620801 2.01 ENST00000648859.1
keratin 17
chr7_+_80133830 1.99 ENST00000648098.1
ENST00000648476.1
ENST00000648412.1
ENST00000648953.1
ENST00000648306.1
ENST00000648832.1
ENST00000648877.1
ENST00000442586.2
ENST00000649487.1
ENST00000649267.1
G protein subunit alpha i1
chr17_-_4560564 1.99 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
gamma-glutamyltransferase 6
chr11_-_128867364 1.98 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr19_+_41219177 1.97 ENST00000301178.9
AXL receptor tyrosine kinase
chr16_+_66379225 1.97 ENST00000563425.2
cadherin 5
chr6_+_133889105 1.95 ENST00000367882.5
transcription factor 21
chr4_+_48986268 1.92 ENST00000226432.9
cell wall biogenesis 43 C-terminal homolog
chr6_+_148342759 1.91 ENST00000367467.8
SAM and SH3 domain containing 1
chr16_+_57619684 1.90 ENST00000568791.5
ENST00000570044.5
adhesion G protein-coupled receptor G1
chr8_+_73294594 1.88 ENST00000240285.10
retinol dehydrogenase 10
chr12_-_57237090 1.86 ENST00000556732.1
NDUFA4 mitochondrial complex associated like 2
chr11_-_128867268 1.85 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr8_-_48921419 1.85 ENST00000020945.4
snail family transcriptional repressor 2
chr3_+_138347648 1.85 ENST00000614350.4
ENST00000289104.8
muscle RAS oncogene homolog
chr15_+_40844171 1.83 ENST00000563656.5
serine peptidase inhibitor, Kunitz type 1
chr19_-_46784905 1.83 ENST00000594991.5
solute carrier family 1 member 5
chrX_-_154354889 1.75 ENST00000438732.2
filamin A
chr6_+_36676489 1.74 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr12_-_52493250 1.73 ENST00000330722.7
keratin 6A
chr16_+_57619709 1.66 ENST00000567553.5
ENST00000565314.5
adhesion G protein-coupled receptor G1
chr19_-_5292770 1.66 ENST00000586065.1
protein tyrosine phosphatase receptor type S
chr20_-_6123019 1.65 ENST00000217289.9
ENST00000536936.1
fermitin family member 1
chr20_+_36091409 1.62 ENST00000202028.9
erythrocyte membrane protein band 4.1 like 1
chr1_-_182604379 1.60 ENST00000367558.6
regulator of G protein signaling 16
chr19_-_46413548 1.59 ENST00000307522.5
coiled-coil domain containing 8
chr13_-_48413105 1.57 ENST00000620633.5
lysophosphatidic acid receptor 6
chr1_+_17249088 1.57 ENST00000375460.3
peptidyl arginine deiminase 3
chrX_-_66639022 1.56 ENST00000374719.8
ectodysplasin A2 receptor
chr11_-_128842467 1.55 ENST00000392664.2
potassium inwardly rectifying channel subfamily J member 1
chr16_-_67966793 1.55 ENST00000541864.6
solute carrier family 12 member 4
chr19_-_17264732 1.50 ENST00000252597.8
USH1 protein network component harmonin binding protein 1
chr1_-_93847150 1.49 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chr18_+_63476927 1.47 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr19_-_46784733 1.45 ENST00000593713.1
ENST00000598022.1
ENST00000434726.6
solute carrier family 1 member 5
chr1_-_79188390 1.43 ENST00000662530.1
adhesion G protein-coupled receptor L4
chr1_-_45623967 1.41 ENST00000445048.2
ENST00000421127.6
ENST00000528266.6
coiled-coil domain containing 17
chr5_-_42811884 1.38 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr12_-_95790755 1.37 ENST00000343702.9
ENST00000344911.8
netrin 4
chr16_+_57619942 1.37 ENST00000568908.5
ENST00000568909.5
ENST00000566778.5
ENST00000561988.5
adhesion G protein-coupled receptor G1
chr15_-_63156774 1.34 ENST00000462430.5
ribosomal protein S27 like
chr15_+_40844064 1.33 ENST00000568823.5
serine peptidase inhibitor, Kunitz type 1
chr22_+_35648438 1.33 ENST00000409652.5
apolipoprotein L6
chr12_-_95791135 1.32 ENST00000538383.5
netrin 4
chr4_+_71339014 1.32 ENST00000340595.4
solute carrier family 4 member 4
chr4_+_69096494 1.32 ENST00000508661.5
ENST00000622664.1
UDP glucuronosyltransferase family 2 member B7
chr3_-_111595339 1.29 ENST00000317012.5
zinc finger BED-type containing 2
chrX_+_67543973 1.27 ENST00000374690.9
androgen receptor
chr1_+_116373233 1.27 ENST00000295598.10
ATPase Na+/K+ transporting subunit alpha 1
chr17_+_19648723 1.27 ENST00000672357.1
ENST00000584332.6
ENST00000176643.11
ENST00000339618.8
ENST00000579855.5
ENST00000671878.1
ENST00000395575.7
aldehyde dehydrogenase 3 family member A2
chr12_-_52452139 1.25 ENST00000252252.4
keratin 6B
chr4_+_69096467 1.25 ENST00000305231.12
UDP glucuronosyltransferase family 2 member B7
chr3_+_69866217 1.24 ENST00000314589.10
melanocyte inducing transcription factor
chr4_-_174522315 1.23 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr11_+_706595 1.21 ENST00000531348.5
ENST00000530636.5
EPS8 like 2
chr1_+_116372647 1.21 ENST00000418797.5
ATPase Na+/K+ transporting subunit alpha 1
chr12_+_119667859 1.20 ENST00000541640.5
protein kinase AMP-activated non-catalytic subunit beta 1
chr4_-_10021490 1.20 ENST00000264784.8
solute carrier family 2 member 9
chr1_-_205850125 1.16 ENST00000367136.5
peptidase M20 domain containing 1
chr11_+_111937320 1.16 ENST00000440460.7
DIX domain containing 1
chr12_+_119668109 1.16 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr4_-_128288163 1.14 ENST00000512483.5
progesterone receptor membrane component 2
chr17_+_19648915 1.14 ENST00000672567.1
ENST00000672709.1
aldehyde dehydrogenase 3 family member A2
chr17_+_19648792 1.13 ENST00000630662.2
aldehyde dehydrogenase 3 family member A2
chr8_-_23164020 1.13 ENST00000312584.4
TNF receptor superfamily member 10d
chr1_+_26159071 1.11 ENST00000374268.5
family with sequence similarity 110 member D
chr8_-_23225061 1.11 ENST00000613472.1
ENST00000221132.8
TNF receptor superfamily member 10a
chr3_-_185254028 1.11 ENST00000440662.1
ENST00000456310.5
ENST00000231887.8
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
chr7_+_75395629 1.09 ENST00000323819.7
ENST00000430211.5
tripartite motif containing 73
chr19_+_12064720 1.09 ENST00000550826.1
ENST00000439326.8
zinc finger protein 844
chr15_+_55408479 1.07 ENST00000569691.2
chromosome 15 open reading frame 65
chr5_-_157059109 1.07 ENST00000523175.6
ENST00000522693.5
hepatitis A virus cellular receptor 1
chr11_-_74467531 1.06 ENST00000310128.9
ENST00000531854.5
ENST00000526855.1
ENST00000529425.5
potassium voltage-gated channel subfamily E regulatory subunit 3
chr3_+_136957948 1.05 ENST00000329582.9
interleukin 20 receptor subunit beta
chr3_+_53168687 1.04 ENST00000650940.1
ENST00000654719.1
protein kinase C delta
chr20_+_58689124 1.04 ENST00000525967.5
ENST00000525817.5
aminopeptidase like 1
chr22_+_37805218 1.03 ENST00000340857.4
H1.0 linker histone
chr19_+_15049469 1.03 ENST00000427043.4
caspase 14
chr19_-_18940289 1.02 ENST00000542541.6
ENST00000433218.6
homer scaffold protein 3
chr14_-_106579223 1.01 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr15_-_55408467 1.01 ENST00000310958.10
cell cycle progression 1
chr1_+_236395394 1.00 ENST00000359362.6
EDAR associated death domain
chr21_-_26090035 0.99 ENST00000448850.5
amyloid beta precursor protein
chr14_+_24310134 0.98 ENST00000533293.2
ENST00000543919.1
leukotriene B4 receptor 2
chr15_-_89690676 0.98 ENST00000561224.5
ENST00000300056.8
peroxisomal biogenesis factor 11 alpha
chr11_-_67629900 0.95 ENST00000301490.8
ENST00000376693.3
nudix hydrolase 8
chr17_-_28335421 0.94 ENST00000578122.5
ENST00000579419.5
ENST00000585313.5
ENST00000578985.5
ENST00000577498.1
ENST00000585089.5
ENST00000357896.7
ENST00000395418.8
ENST00000588477.5
intraflagellar transport 20
chr1_+_86424154 0.93 ENST00000370565.5
chloride channel accessory 2
chr3_+_122325237 0.93 ENST00000264474.4
ENST00000479204.1
cystatin A
chr6_+_18387326 0.92 ENST00000259939.4
ring finger protein 144B
chr16_+_82056423 0.91 ENST00000568090.5
hydroxysteroid 17-beta dehydrogenase 2
chr19_+_35358460 0.91 ENST00000327809.5
free fatty acid receptor 3
chr11_+_64306227 0.91 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr4_-_128288791 0.90 ENST00000613358.4
ENST00000520121.6
progesterone receptor membrane component 2
chr11_-_78139258 0.88 ENST00000530910.6
ENST00000681417.1
ENST00000681225.1
ENST00000681765.1
ENST00000525870.6
ENST00000530608.6
ENST00000532306.6
ENST00000376156.7
ENST00000681699.1
ENST00000681221.1
ENST00000679444.1
ENST00000680829.1
ENST00000680761.1
ENST00000680256.1
ENST00000525783.6
ENST00000529139.6
ENST00000680580.1
ENST00000526849.6
ENST00000680399.1
ENST00000527099.2
ENST00000681489.1
ENST00000299626.10
ENST00000679497.1
ENST00000680101.1
ENST00000532440.6
ENST00000530454.6
ENST00000525761.3
ENST00000681575.1
ENST00000679559.1
ENST00000680398.1
ENST00000615266.5
ENST00000680643.1
ALG8 alpha-1,3-glucosyltransferase
chr7_+_140696665 0.86 ENST00000476279.5
ENST00000461457.1
ENST00000465506.5
NADH:ubiquinone oxidoreductase subunit B2
chr4_+_71339037 0.85 ENST00000512686.5
solute carrier family 4 member 4
chr2_-_201642653 0.85 ENST00000621467.4
transmembrane protein 237
chr4_-_143905529 0.85 ENST00000358615.9
ENST00000437468.2
glycophorin E (MNS blood group)
chr15_-_63157464 0.84 ENST00000330964.10
ENST00000635699.1
ENST00000439025.1
ribosomal protein S27 like
chr7_+_140696696 0.84 ENST00000247866.9
ENST00000464566.5
NADH:ubiquinone oxidoreductase subunit B2
chr19_-_11738882 0.84 ENST00000586121.1
ENST00000431998.1
ENST00000341191.11
ENST00000440527.1
zinc finger protein 823
chr2_-_31138429 0.84 ENST00000349752.10
polypeptide N-acetylgalactosaminyltransferase 14
chr1_-_185317234 0.82 ENST00000367498.8
influenza virus NS1A binding protein
chr16_-_57764340 0.82 ENST00000565270.1
kinesin family member C3
chr11_-_76210736 0.81 ENST00000529461.1
Wnt family member 11
chr17_+_79074822 0.80 ENST00000311595.14
ENST00000579016.6
endo-beta-N-acetylglucosaminidase
chr16_+_57620077 0.80 ENST00000567835.5
ENST00000569372.5
ENST00000563548.5
ENST00000562003.5
adhesion G protein-coupled receptor G1
chr5_-_136193143 0.79 ENST00000607574.2
small integral membrane protein 32
chr7_-_85187039 0.78 ENST00000284136.11
semaphorin 3D
chr17_+_74987581 0.78 ENST00000337231.5
cerebellar degeneration related protein 2 like
chr15_+_51829644 0.78 ENST00000308580.12
tropomodulin 3
chr11_+_47586678 0.77 ENST00000538490.3
family with sequence similarity 180 member B
chr22_+_22697789 0.77 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr8_-_23069012 0.77 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr5_+_163437569 0.76 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
cyclin G1
chr5_-_180803830 0.76 ENST00000427865.2
ENST00000514283.1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chrX_+_152917830 0.75 ENST00000318529.12
zinc finger protein 185 with LIM domain
chr19_+_12064781 0.75 ENST00000441304.2
zinc finger protein 844
chr5_+_126462339 0.74 ENST00000502348.5
GRAM domain containing 2B
chr13_+_23180960 0.74 ENST00000218867.4
sarcoglycan gamma
chr4_-_40514543 0.73 ENST00000513473.5
RNA binding motif protein 47
chr9_-_127937800 0.72 ENST00000373110.4
ENST00000314392.13
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr8_-_73294425 0.70 ENST00000396465.5
ribosomal protein L7
chrX_-_66639255 0.69 ENST00000451436.6
ectodysplasin A2 receptor
chr6_+_150683593 0.69 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr1_-_37692205 0.67 ENST00000477060.1
ENST00000491981.5
ENST00000488137.5
ENST00000619962.1
chromosome 1 open reading frame 109
chr17_-_35753211 0.67 ENST00000604641.6
growth arrest specific 2 like 2
chr3_+_184363351 0.67 ENST00000443489.5
RNA polymerase II, I and III subunit H
chr11_+_27040826 0.66 ENST00000533566.5
gamma-butyrobetaine hydroxylase 1
chr17_+_28335653 0.66 ENST00000578158.5
TNF alpha induced protein 1
chr5_+_116084992 0.66 ENST00000274458.9
ENST00000632434.1
COMM domain containing 10
chr15_-_55408018 0.65 ENST00000569205.5
cell cycle progression 1
chr17_+_28335718 0.64 ENST00000226225.7
TNF alpha induced protein 1
chr15_+_51829625 0.64 ENST00000558455.1
tropomodulin 3
chr8_-_97277890 0.63 ENST00000322128.5
TSPY like 5
chr2_-_31138503 0.62 ENST00000430167.1
polypeptide N-acetylgalactosaminyltransferase 14
chr12_-_52191981 0.61 ENST00000313234.9
keratin 80
chr7_-_73328082 0.60 ENST00000333149.7
tripartite motif containing 50
chr1_+_153775357 0.59 ENST00000624995.4
solute carrier family 27 member 3
chr12_-_57765591 0.59 ENST00000546567.5
cytochrome P450 family 27 subfamily B member 1
chr3_-_88059042 0.58 ENST00000309534.10
CGG triplet repeat binding protein 1
chr12_-_52192007 0.58 ENST00000394815.3
keratin 80
chr10_+_87863595 0.58 ENST00000371953.8
phosphatase and tensin homolog
chr2_-_177392673 0.57 ENST00000447413.1
ENST00000397057.6
ENST00000456746.5
ENST00000464747.5
novel transcript
nuclear factor, erythroid 2 like 2
chr3_+_184363387 0.57 ENST00000452961.5
RNA polymerase II, I and III subunit H

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.9 3.5 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.8 3.3 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.8 4.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.8 10.2 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.8 2.3 GO:0070662 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.7 2.8 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.7 2.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.6 3.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.6 3.8 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.6 1.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6 3.6 GO:0090131 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.5 2.5 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.4 3.1 GO:0003383 apical constriction(GO:0003383)
0.4 1.7 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.4 1.3 GO:1902905 positive regulation of fibril organization(GO:1902905)
0.4 3.7 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.4 1.6 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.4 0.8 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.4 7.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4 2.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 2.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 1.1 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.4 1.4 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4 1.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.3 3.9 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.3 1.6 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 1.2 GO:0043605 cellular amide catabolic process(GO:0043605)
0.3 2.0 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.3 3.0 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 1.9 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 1.0 GO:2000754 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
0.3 2.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 1.3 GO:0060748 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 2.0 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.2 5.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 2.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 4.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 6.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 2.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 2.5 GO:0031944 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.2 1.9 GO:0060431 primary lung bud formation(GO:0060431)
0.2 1.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 2.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 1.0 GO:0051563 microglia differentiation(GO:0014004) microglia development(GO:0014005) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.2 2.4 GO:0035878 nail development(GO:0035878)
0.2 3.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 4.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.2 2.0 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.6 GO:0090071 rhythmic synaptic transmission(GO:0060024) negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 4.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 1.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.2 GO:0051601 exocyst localization(GO:0051601)
0.1 1.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.7 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 2.0 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 2.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 3.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.8 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 3.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.3 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) mesodermal cell migration(GO:0008078) cardiac cell fate determination(GO:0060913) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.5 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 3.7 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 2.0 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 2.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.5 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 1.2 GO:0097070 ductus arteriosus closure(GO:0097070)
0.1 0.6 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 1.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.2 GO:0060733 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.1 0.2 GO:0030221 basophil differentiation(GO:0030221) astrocyte fate commitment(GO:0060018)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 3.4 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 2.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.2 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.1 GO:1902908 regulation of melanosome transport(GO:1902908)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 1.0 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 4.1 GO:0010107 potassium ion import(GO:0010107)
0.1 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 2.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 2.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.5 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.5 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 2.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.5 GO:0009629 response to gravity(GO:0009629)
0.0 0.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.9 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.3 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 4.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 2.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 3.0 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.2 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 3.1 GO:0070268 cornification(GO:0070268)
0.0 0.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 2.3 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.7 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.8 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.5 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.3 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0036117 hyaluranon cable(GO:0036117)
0.7 3.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.7 2.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.6 4.0 GO:0031523 Myb complex(GO:0031523)
0.5 3.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 3.3 GO:0005610 laminin-5 complex(GO:0005610)
0.3 0.9 GO:1902636 kinociliary basal body(GO:1902636)
0.3 5.7 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 0.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 1.6 GO:1990393 3M complex(GO:1990393)
0.2 3.6 GO:0097512 cardiac myofibril(GO:0097512)
0.2 4.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 8.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.0 GO:0044753 amphisome(GO:0044753)
0.1 2.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 3.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.5 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.4 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 2.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.8 GO:0005922 connexon complex(GO:0005922)
0.1 1.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 1.3 GO:0097413 Lewy body(GO:0097413)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.8 GO:0005915 zonula adherens(GO:0005915)
0.1 2.0 GO:0033643 host cell part(GO:0033643)
0.1 2.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.2 GO:0000145 exocyst(GO:0000145)
0.1 2.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 5.0 GO:0045095 keratin filament(GO:0045095)
0.0 9.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 3.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 6.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.0 GO:0099738 cell cortex region(GO:0099738)
0.0 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.0 GO:0045178 basal part of cell(GO:0045178)
0.0 3.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 3.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 7.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 1.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
1.0 6.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.8 10.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.8 3.3 GO:0045569 TRAIL binding(GO:0045569)
0.7 3.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.7 2.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.5 2.6 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.5 2.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 2.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 5.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 4.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.4 6.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 1.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.4 3.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.3 1.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 2.8 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 2.7 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.0 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.3 3.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 0.7 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 0.7 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.2 0.9 GO:0002046 opsin binding(GO:0002046)
0.2 0.9 GO:0004583 alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.2 1.3 GO:0004882 androgen receptor activity(GO:0004882)
0.2 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.6 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.2 3.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 0.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 2.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 2.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.5 GO:1990239 steroid hormone binding(GO:1990239)
0.1 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 2.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 1.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 5.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 2.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.3 GO:0004630 phospholipase D activity(GO:0004630)
0.1 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 4.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 1.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 4.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 2.2 GO:0008494 translation activator activity(GO:0008494)
0.1 2.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 3.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 2.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.4 GO:0008430 selenium binding(GO:0008430)
0.1 4.4 GO:0042379 chemokine receptor binding(GO:0042379)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 3.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 3.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 1.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 3.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 7.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 5.2 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 3.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.8 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 2.6 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 10.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 11.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 6.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 6.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 3.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 14.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 3.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.2 5.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 2.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 5.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 9.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 3.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 3.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 5.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 2.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere