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Illumina Body Map 2 (GSE30611)

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Results for TP73

Z-value: 0.81

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Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
ENSG00000078900.15 tumor protein p73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg38_v1_chr1_+_3698027_36980580.241.9e-01Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_74174403 1.78 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine rich repeat
chr12_+_49295138 1.71 ENST00000257860.9
peripherin
chr1_+_46671821 1.66 ENST00000334122.5
ENST00000415500.1
testis expressed 38
chr15_+_40844018 1.63 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr2_-_165794190 1.61 ENST00000392701.8
ENST00000422973.1
polypeptide N-acetylgalactosaminyltransferase 3
chr2_+_176116768 1.49 ENST00000249501.5
homeobox D10
chr1_+_46671871 1.40 ENST00000564373.1
testis expressed 38
chr2_+_219572304 1.38 ENST00000243786.3
inhibin subunit alpha
chr9_+_36169382 1.31 ENST00000335119.4
calicin
chr19_+_44777860 1.30 ENST00000341505.4
ENST00000647358.2
Cbl proto-oncogene C
chr2_+_95274439 1.27 ENST00000317620.14
ENST00000403131.6
ENST00000317668.8
prominin 2
chr15_+_40844506 1.11 ENST00000568580.5
serine peptidase inhibitor, Kunitz type 1
chr1_-_153615858 1.10 ENST00000476873.5
S100 calcium binding protein A14
chr1_-_204190324 1.06 ENST00000638118.1
renin
chr15_+_75206398 1.06 ENST00000565074.1
chromosome 15 open reading frame 39
chr15_+_75206014 1.06 ENST00000567617.1
chromosome 15 open reading frame 39
chr1_+_239386942 0.93 ENST00000675184.1
cholinergic receptor muscarinic 3
chr19_+_43716070 0.92 ENST00000244314.6
immunity related GTPase cinema
chr11_+_46277648 0.90 ENST00000621158.5
cAMP responsive element binding protein 3 like 1
chr10_-_103452356 0.88 ENST00000260743.10
calcium homeostasis modulator family member 2
chr22_-_37580075 0.87 ENST00000215886.6
galectin 2
chr15_+_40844171 0.86 ENST00000563656.5
serine peptidase inhibitor, Kunitz type 1
chr19_+_3721719 0.86 ENST00000589378.5
tight junction protein 3
chr10_-_103452384 0.85 ENST00000369788.7
calcium homeostasis modulator family member 2
chr11_+_60429567 0.85 ENST00000300190.7
membrane spanning 4-domains A5
chr19_-_35490456 0.85 ENST00000338897.4
ENST00000484218.6
keratinocyte differentiation associated protein
chr6_+_36676455 0.81 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chrX_+_9912434 0.81 ENST00000418909.6
shroom family member 2
chr6_+_36676489 0.78 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr2_+_219418369 0.78 ENST00000373960.4
desmin
chr5_-_157166262 0.78 ENST00000302938.4
family with sequence similarity 71 member B
chr7_+_142939343 0.76 ENST00000458732.1
ENST00000409607.5
LLLL and CFNLAS motif containing 1
chr8_+_37796850 0.76 ENST00000412232.3
adhesion G protein-coupled receptor A2
chr8_+_119873710 0.74 ENST00000523492.5
ENST00000286234.6
DEP domain containing MTOR interacting protein
chr19_+_43716095 0.74 ENST00000596627.1
immunity related GTPase cinema
chr8_+_37796906 0.73 ENST00000315215.11
adhesion G protein-coupled receptor A2
chr10_-_77926724 0.73 ENST00000372391.7
discs large MAGUK scaffold protein 5
chr2_-_229271221 0.72 ENST00000392054.7
ENST00000409462.1
ENST00000392055.8
phosphotyrosine interaction domain containing 1
chr2_-_26641363 0.72 ENST00000288861.5
calcium and integrin binding family member 4
chr9_+_35673917 0.72 ENST00000617161.1
ENST00000378357.9
carbonic anhydrase 9
chrX_-_81121663 0.71 ENST00000430960.5
ENST00000447319.5
high mobility group nucleosome binding domain 5
chr11_+_77589911 0.69 ENST00000313578.4
aquaporin 11
chr12_-_91179472 0.68 ENST00000550099.5
ENST00000546391.5
decorin
chr5_+_38258373 0.67 ENST00000354891.7
EGF like, fibronectin type III and laminin G domains
chr19_+_35106510 0.66 ENST00000648240.1
novel protein
chr19_+_44751251 0.66 ENST00000444487.1
BCL3 transcription coactivator
chr5_+_38258551 0.65 ENST00000322350.10
EGF like, fibronectin type III and laminin G domains
chr4_+_38664189 0.64 ENST00000514033.1
ENST00000261438.10
Kruppel like factor 3
chr1_-_236065079 0.62 ENST00000264187.7
ENST00000366595.7
nidogen 1
chr17_+_74431338 0.61 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chr10_+_68901258 0.61 ENST00000373585.8
DExD-box helicase 50
chr1_-_68232514 0.60 ENST00000262348.9
ENST00000370973.2
ENST00000370971.1
Wnt ligand secretion mediator
chr1_-_68232539 0.60 ENST00000370976.7
ENST00000354777.6
Wnt ligand secretion mediator
chr16_+_84145256 0.58 ENST00000378553.10
dynein axonemal assembly factor 1
chr9_-_135499846 0.58 ENST00000429260.7
chromosome 9 open reading frame 116
chrX_-_81121619 0.58 ENST00000373250.7
high mobility group nucleosome binding domain 5
chrX_+_153642473 0.56 ENST00000370167.8
dual specificity phosphatase 9
chr11_+_31812307 0.55 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAX6 upstream antisense RNA
novel protein
chr2_+_69741974 0.55 ENST00000409920.5
annexin A4
chr1_+_27959943 0.53 ENST00000675575.1
ENST00000373884.6
XK related 8
chrX_+_131058340 0.53 ENST00000276211.10
ENST00000370922.5
Rho GTPase activating protein 36
chr1_+_239386556 0.52 ENST00000676153.1
cholinergic receptor muscarinic 3
chr3_+_136957948 0.52 ENST00000329582.9
interleukin 20 receptor subunit beta
chr17_-_76027296 0.52 ENST00000301607.8
envoplakin
chr1_+_100352925 0.51 ENST00000644813.1
cell division cycle 14A
chr14_+_52314280 0.50 ENST00000557436.1
ENST00000245457.6
prostaglandin E receptor 2
chr7_+_69967464 0.49 ENST00000664521.1
activator of transcription and developmental regulator AUTS2
chr17_+_39200507 0.49 ENST00000678573.1
ribosomal protein L19
chr6_+_36130586 0.49 ENST00000373759.1
mitogen-activated protein kinase 13
chr19_+_41860236 0.48 ENST00000601492.5
ENST00000600467.6
ENST00000598742.6
ENST00000221975.6
ENST00000598261.2
ribosomal protein S19
chr4_-_156970903 0.48 ENST00000422544.2
platelet derived growth factor C
chr17_+_32928126 0.48 ENST00000579849.6
ENST00000578289.5
ENST00000439138.5
transmembrane protein 98
chrX_+_9912548 0.48 ENST00000452575.1
shroom family member 2
chr17_+_39200275 0.47 ENST00000225430.9
ribosomal protein L19
chr17_+_39200334 0.47 ENST00000579260.5
ENST00000582193.5
ribosomal protein L19
chr17_+_54900824 0.46 ENST00000572405.5
ENST00000572158.5
ENST00000575882.6
ENST00000572298.5
ENST00000536554.5
ENST00000575333.5
ENST00000570499.5
ENST00000572576.5
target of myb1 like 1 membrane trafficking protein
chr17_-_44123628 0.46 ENST00000587135.1
ENST00000225983.10
ENST00000682912.1
ENST00000588703.5
histone deacetylase 5
chr15_+_40844064 0.45 ENST00000568823.5
serine peptidase inhibitor, Kunitz type 1
chr17_+_7888783 0.43 ENST00000330494.12
ENST00000358181.8
chromodomain helicase DNA binding protein 3
chr9_-_114505437 0.43 ENST00000374057.3
ENST00000362057.4
ENST00000673697.1
whirlin
chr17_-_76027212 0.43 ENST00000586740.1
envoplakin
chr1_-_203086001 0.42 ENST00000241651.5
myogenin
chr16_+_89918855 0.41 ENST00000555147.2
melanocortin 1 receptor
chr17_-_5123102 0.40 ENST00000250076.7
zinc finger protein 232
chr17_+_39200302 0.39 ENST00000579374.5
ribosomal protein L19
chr9_-_20382461 0.38 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr14_-_74612021 0.38 ENST00000556690.5
latent transforming growth factor beta binding protein 2
chr3_-_185821092 0.38 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr17_-_81514629 0.37 ENST00000681052.1
ENST00000575659.6
actin gamma 1
chr10_+_46375619 0.37 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr17_+_56153458 0.35 ENST00000318698.6
ENST00000682825.1
ENST00000566473.6
ankyrin repeat and fibronectin type III domain containing 1
chr4_+_109560219 0.34 ENST00000394650.7
mitochondrial calcium uniporter dominant negative subunit beta
chr3_-_171026709 0.33 ENST00000314251.8
solute carrier family 2 member 2
chr3_+_44976236 0.32 ENST00000265564.8
exosome component 7
chr9_-_129620743 0.31 ENST00000619117.1
ENST00000372478.4
chromosome 9 open reading frame 50
chr14_+_21749163 0.31 ENST00000390427.3
T cell receptor alpha variable 5
chr7_-_128405930 0.30 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
inosine monophosphate dehydrogenase 1
chr12_+_82358496 0.29 ENST00000248306.8
ENST00000548200.5
methyltransferase like 25
chr12_-_82358380 0.28 ENST00000256151.8
ENST00000552377.5
coiled-coil domain containing 59
chr6_-_33288887 0.28 ENST00000444176.1
WD repeat domain 46
chr19_+_41350911 0.28 ENST00000539627.5
transmembrane protein 91
chr11_+_60429595 0.27 ENST00000528905.1
ENST00000528093.1
membrane spanning 4-domains A5
chr2_-_38602626 0.26 ENST00000378915.7
heterogeneous nuclear ribonucleoprotein L like
chr14_-_89954659 0.25 ENST00000555070.1
ENST00000316738.12
ENST00000538485.6
ENST00000556609.5
novel transcript
EF-hand calcium binding domain 11
chr16_+_2019777 0.25 ENST00000566435.4
neuropeptide W
chr2_+_127535746 0.24 ENST00000428314.5
ENST00000409816.7
myosin VIIB
chr17_-_40867200 0.24 ENST00000647902.1
ENST00000251643.5
keratin 12
chr9_+_6757940 0.24 ENST00000381309.8
lysine demethylase 4C
chr10_-_60140515 0.23 ENST00000486349.2
ankyrin 3
chr20_-_54173516 0.23 ENST00000395955.7
cytochrome P450 family 24 subfamily A member 1
chr17_+_67825664 0.23 ENST00000321892.8
bromodomain PHD finger transcription factor
chr1_+_16043776 0.22 ENST00000375679.9
chloride voltage-gated channel Kb
chr10_+_46375721 0.22 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
novel transcript
annexin A8 like 1
chr4_+_105710809 0.22 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr6_+_43576205 0.21 ENST00000372226.1
ENST00000443535.1
DNA polymerase eta
chr15_+_64387828 0.21 ENST00000261884.8
thyroid hormone receptor interactor 4
chr12_+_43758936 0.20 ENST00000440781.6
ENST00000431837.5
ENST00000550616.5
ENST00000613694.5
ENST00000551736.5
interleukin 1 receptor associated kinase 4
chr1_-_160862880 0.20 ENST00000368034.9
CD244 molecule
chr6_-_33289189 0.20 ENST00000374617.9
WD repeat domain 46
chr17_-_49414802 0.20 ENST00000511832.6
ENST00000419140.7
ENST00000617874.5
prohibitin
chr20_+_41136944 0.19 ENST00000244007.7
phospholipase C gamma 1
chr19_-_13937991 0.19 ENST00000254320.7
ENST00000586075.1
podocan like 1
chr1_-_235161215 0.19 ENST00000447801.5
ENST00000408888.8
ENST00000429912.1
RNA binding motif protein 34
chr19_-_35742431 0.18 ENST00000592537.5
ENST00000246532.6
ENST00000588992.5
IGF like family receptor 1
chr16_-_14630200 0.18 ENST00000650990.1
ENST00000651049.1
ENST00000652727.1
ENST00000652501.1
ENST00000539279.5
ENST00000651634.1
ENST00000651027.1
ENST00000420015.6
ENST00000651865.1
ENST00000437198.7
ENST00000341484.11
ENST00000650960.1
poly(A)-specific ribonuclease
chr11_+_71527267 0.17 ENST00000398536.6
keratin associated protein 5-7
chr10_+_46375645 0.16 ENST00000622769.4
annexin A8 like 1
chr10_-_89535575 0.15 ENST00000371790.5
solute carrier family 16 member 12
chr1_+_16043736 0.15 ENST00000619181.4
chloride voltage-gated channel Kb
chr14_+_75278820 0.15 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr16_+_30923565 0.14 ENST00000338343.10
F-box and leucine rich repeat protein 19
chr4_+_6716131 0.14 ENST00000320776.5
biogenesis of lysosomal organelles complex 1 subunit 4
chr13_+_50910018 0.14 ENST00000645990.1
ENST00000642995.1
ENST00000636524.2
ENST00000643159.1
ENST00000645618.1
ENST00000611510.5
ENST00000642454.1
ENST00000646709.1
ribonuclease H2 subunit B
chr17_-_49414871 0.14 ENST00000504124.6
ENST00000300408.8
ENST00000614445.5
prohibitin
chr6_+_31547560 0.14 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr17_+_67825494 0.13 ENST00000306378.11
ENST00000544778.6
bromodomain PHD finger transcription factor
chr16_-_67966793 0.13 ENST00000541864.6
solute carrier family 12 member 4
chr1_-_51878711 0.13 ENST00000352171.12
nardilysin convertase
chr1_-_160862700 0.12 ENST00000322302.7
ENST00000368033.7
CD244 molecule
chr14_+_22086401 0.11 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr19_-_38735405 0.11 ENST00000597987.5
ENST00000595177.1
calpain 12
chr9_-_20382448 0.10 ENST00000491137.5
MLLT3 super elongation complex subunit
chr9_+_128683645 0.10 ENST00000372692.8
SET nuclear proto-oncogene
chr17_-_30334050 0.09 ENST00000328886.5
ENST00000538566.6
transmembrane and immunoglobulin domain containing 1
chr19_+_43533384 0.09 ENST00000601282.1
zinc finger protein 575
chr8_-_144063951 0.08 ENST00000567871.2
5-oxoprolinase, ATP-hydrolysing
chr14_+_75279637 0.08 ENST00000555686.1
ENST00000555672.1
Fos proto-oncogene, AP-1 transcription factor subunit
chrX_+_154542194 0.07 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr20_-_54173976 0.07 ENST00000216862.8
cytochrome P450 family 24 subfamily A member 1
chr10_+_62804710 0.07 ENST00000373783.3
2-aminoethanethiol dioxygenase
chr10_-_97426044 0.07 ENST00000536831.5
ENST00000622320.4
ENST00000439965.6
ribosomal RNA processing 12 homolog
chr1_-_182672232 0.05 ENST00000508450.5
regulator of G protein signaling 8
chr22_+_35383106 0.05 ENST00000678411.1
heme oxygenase 1
chr6_+_43576119 0.05 ENST00000372236.9
DNA polymerase eta
chr1_-_220046432 0.04 ENST00000609181.5
ENST00000366923.8
glutamyl-prolyl-tRNA synthetase 1
chr19_-_1863497 0.04 ENST00000617223.1
ENST00000250916.6
Kruppel like factor 16
chrX_-_132094263 0.04 ENST00000370879.5
FERM domain containing 7
chrX_+_73447042 0.03 ENST00000373514.3
caudal type homeobox 4
chr2_-_27134611 0.02 ENST00000406567.7
ENST00000260643.7
prolactin regulatory element binding
chrX_-_139642518 0.02 ENST00000370573.8
ENST00000338585.6
MCF.2 cell line derived transforming sequence
chr1_+_156815633 0.02 ENST00000392302.7
ENST00000674537.1
neurotrophic receptor tyrosine kinase 1
chr17_+_21288029 0.02 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr11_+_111977300 0.02 ENST00000615255.1
DIX domain containing 1
chr1_-_77979054 0.02 ENST00000370768.7
ENST00000370767.5
ENST00000421641.1
far upstream element binding protein 1
chr9_+_113580912 0.02 ENST00000471324.6
regulator of G protein signaling 3
chr1_-_51878799 0.02 ENST00000354831.11
ENST00000544028.5
nardilysin convertase
chr19_+_12995554 0.01 ENST00000397661.6
nuclear factor I X
chr9_+_6758133 0.01 ENST00000543771.5
lysine demethylase 4C

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0008057 eye pigment granule organization(GO:0008057)
0.4 1.3 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.3 1.4 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.3 1.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 1.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.7 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 1.5 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.2 0.7 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 1.6 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 1.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 0.5 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 1.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 0.5 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 4.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.9 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.3 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.1 0.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 2.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 1.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.2 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 1.9 GO:0097421 liver regeneration(GO:0097421)
0.0 1.0 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.8 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.5 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.7 GO:0033574 response to testosterone(GO:0033574)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.3 GO:0033150 cytoskeletal calyx(GO:0033150)
0.3 1.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.3 GO:0044393 microspike(GO:0044393)
0.2 1.5 GO:0032279 asymmetric synapse(GO:0032279)
0.2 0.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.2 GO:0090651 apical cytoplasm(GO:0090651)
0.1 0.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 1.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.9 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.1 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP