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Illumina Body Map 2 (GSE30611)
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Results for UACAGUA
Z-value: 0.57
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miRNA associated with seed UACAGUA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-101-3p.2
|
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_-_59893718 Show fit | 1.13 |
ENST00000340635.11
|
phosphodiesterase 4D |
|
| chr8_-_123541197 Show fit | 1.08 |
ENST00000517956.5
ENST00000443022.2 |
F-box protein 32 |
|
| chr8_-_65842051 Show fit | 1.01 |
ENST00000401827.8
|
phosphodiesterase 7A |
|
| chrX_-_33128360 Show fit | 0.96 |
ENST00000378677.6
|
dystrophin |
|
| chr12_-_110583305 Show fit | 0.88 |
ENST00000354300.5
|
protein phosphatase targeting COQ7 |
|
| chr8_-_74321532 Show fit | 0.84 |
ENST00000342232.5
|
junctophilin 1 |
|
| chr11_+_33257265 Show fit | 0.79 |
ENST00000303296.9
ENST00000379016.7 |
homeodomain interacting protein kinase 3 |
|
| chr10_+_58334998 Show fit | 0.78 |
ENST00000373910.9
|
ubiquitin conjugating enzyme E2 D1 |
|
| chr8_-_23854796 Show fit | 0.76 |
ENST00000290271.7
|
stanniocalcin 1 |
|
| chr2_-_178807415 Show fit | 0.76 |
ENST00000342992.10
ENST00000460472.6 ENST00000589042.5 ENST00000591111.5 ENST00000360870.10 |
titin |
Network of associatons between targets according to the STRING database.
First level regulatory network of UACAGUA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 1.2 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 0.0 | 1.2 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.1 | 1.1 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.1 | 1.1 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.1 | 1.0 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 1.0 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 0.8 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.1 | 0.8 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.0 | 0.8 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.1 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 1.0 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 1.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 0.8 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 0.8 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.1 | 0.7 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 0.6 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 0.5 | GO:0005899 | insulin receptor complex(GO:0005899) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.5 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 1.5 | GO:0061650 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 1.0 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 0.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.8 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 0.8 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.2 | 0.7 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.1 | 0.7 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.1 | 0.7 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.1 | 0.7 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 1.3 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.0 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.7 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.7 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.7 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 0.4 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.3 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.3 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.9 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.9 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.5 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.5 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.5 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.4 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 0.3 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |