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Illumina Body Map 2 (GSE30611)

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Results for UCACAGU

Z-value: 1.44

Motif logo

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miRNA associated with seed UCACAGU

NamemiRBASE accession
hsa-miR-27a-3p
MIMAT0000084
hsa-miR-27b-3p
MIMAT0000419

Activity profile of UCACAGU motif

Sorted Z-values of UCACAGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_10218808 4.87 ENST00000254976.7
ENST00000304886.6
SNAP25
synaptosome associated protein 25
chr1_+_39955112 4.36 ENST00000420632.6
ENST00000372811.10
ENST00000434861.5
ENST00000372809.5
MFSD2A
major facilitator superfamily domain containing 2A
chr20_-_14337602 3.73 ENST00000378053.3
ENST00000341420.5
FLRT3
fibronectin leucine rich transmembrane protein 3
chr7_+_94656325 3.47 ENST00000482108.1
ENST00000488574.5
ENST00000612748.1
ENST00000613043.1
PEG10
paternally expressed 10
chr15_-_74433942 3.26 ENST00000543145.6
ENST00000261918.9
SEMA7A
semaphorin 7A (John Milton Hagen blood group)
chr5_+_168291599 3.24 ENST00000265293.9
WWC1
WW and C2 domain containing 1
chr11_+_121452291 3.23 ENST00000260197.12
SORL1
sortilin related receptor 1
chr1_-_47190013 3.20 ENST00000294338.7
PDZK1IP1
PDZK1 interacting protein 1
chr4_+_84583037 3.19 ENST00000295887.6
CDS1
CDP-diacylglycerol synthase 1
chr7_-_27143672 3.18 ENST00000222726.4
HOXA5
homeobox A5
chr11_+_34621065 3.16 ENST00000257831.8
EHF
ETS homologous factor
chr15_+_80779343 3.00 ENST00000220244.7
ENST00000394685.8
ENST00000356249.9
CEMIP
cell migration inducing hyaluronidase 1
chr5_-_58460076 2.89 ENST00000274289.8
ENST00000617412.1
PLK2
polo like kinase 2
chr5_-_116574802 2.88 ENST00000343348.11
SEMA6A
semaphorin 6A
chr1_-_94927079 2.76 ENST00000370206.9
ENST00000394202.8
CNN3
calponin 3
chrX_+_103376488 2.74 ENST00000361298.9
BEX3
brain expressed X-linked 3
chr8_+_40153475 2.59 ENST00000315792.5
TCIM
transcriptional and immune response regulator
chr4_+_114598738 2.54 ENST00000507710.1
ENST00000310836.11
UGT8
UDP glycosyltransferase 8
chr12_+_78864768 2.33 ENST00000261205.9
ENST00000457153.6
SYT1
synaptotagmin 1
chr10_-_15719885 2.31 ENST00000378076.4
ITGA8
integrin subunit alpha 8
chr6_+_41638438 2.28 ENST00000441667.5
ENST00000230321.11
ENST00000373050.8
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr9_-_133992281 2.24 ENST00000406606.7
VAV2
vav guanine nucleotide exchange factor 2
chr3_+_139935176 2.18 ENST00000458420.7
CLSTN2
calsyntenin 2
chr6_+_135851681 2.12 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr17_-_8630713 2.11 ENST00000411957.1
ENST00000360416.8
MYH10
myosin heavy chain 10
chr9_+_130172343 2.06 ENST00000372398.6
NCS1
neuronal calcium sensor 1
chr9_-_127980976 2.06 ENST00000373095.6
FAM102A
family with sequence similarity 102 member A
chr1_-_204359885 2.06 ENST00000414478.1
ENST00000272203.8
PLEKHA6
pleckstrin homology domain containing A6
chr12_-_48957445 1.97 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ARF3
ADP ribosylation factor 3
chr5_+_52989314 1.95 ENST00000296585.10
ITGA2
integrin subunit alpha 2
chr2_-_165794190 1.94 ENST00000392701.8
ENST00000422973.1
GALNT3
polypeptide N-acetylgalactosaminyltransferase 3
chr4_-_88697810 1.93 ENST00000323061.7
NAP1L5
nucleosome assembly protein 1 like 5
chr3_+_10992717 1.93 ENST00000642767.1
ENST00000425938.6
ENST00000642515.1
ENST00000643498.1
ENST00000646072.1
ENST00000646570.1
ENST00000287766.10
ENST00000645281.1
ENST00000642820.1
ENST00000645054.1
ENST00000642735.1
ENST00000646022.1
ENST00000645776.1
ENST00000645592.1
ENST00000646924.1
ENST00000645974.1
ENST00000644314.1
ENST00000642639.1
ENST00000646060.1
ENST00000642201.1
ENST00000646487.1
ENST00000647194.1
ENST00000646088.1
SLC6A1
solute carrier family 6 member 1
chr6_+_19837362 1.92 ENST00000378700.8
ID4
inhibitor of DNA binding 4, HLH protein
chr8_-_41309434 1.91 ENST00000220772.8
SFRP1
secreted frizzled related protein 1
chr1_-_56579555 1.90 ENST00000371250.4
PLPP3
phospholipid phosphatase 3
chr15_-_63381835 1.89 ENST00000344366.7
ENST00000178638.8
ENST00000422263.2
CA12
carbonic anhydrase 12
chr3_-_31981228 1.86 ENST00000396556.7
ENST00000438237.6
OSBPL10
oxysterol binding protein like 10
chr17_+_49495286 1.83 ENST00000172229.8
NGFR
nerve growth factor receptor
chr5_+_132813283 1.82 ENST00000378693.4
SOWAHA
sosondowah ankyrin repeat domain family member A
chr8_-_59119121 1.77 ENST00000361421.2
TOX
thymocyte selection associated high mobility group box
chr15_+_96330691 1.76 ENST00000394166.8
NR2F2
nuclear receptor subfamily 2 group F member 2
chr9_+_134641768 1.74 ENST00000371817.8
ENST00000618395.4
COL5A1
collagen type V alpha 1 chain
chr6_-_39229465 1.74 ENST00000359534.4
KCNK5
potassium two pore domain channel subfamily K member 5
chr1_-_94541746 1.73 ENST00000334047.12
F3
coagulation factor III, tissue factor
chr15_-_79090760 1.73 ENST00000419573.7
ENST00000558480.7
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1
chr5_-_177554545 1.73 ENST00000514747.6
FAM193B
family with sequence similarity 193 member B
chr3_+_113838772 1.73 ENST00000358160.9
GRAMD1C
GRAM domain containing 1C
chr2_-_27495185 1.71 ENST00000264703.4
FNDC4
fibronectin type III domain containing 4
chr5_-_43313403 1.69 ENST00000325110.11
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr1_+_160400543 1.68 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr6_-_119078642 1.68 ENST00000621231.4
ENST00000338891.12
FAM184A
family with sequence similarity 184 member A
chr11_+_130159773 1.68 ENST00000278742.6
ST14
ST14 transmembrane serine protease matriptase
chr15_+_80695277 1.67 ENST00000258884.5
ENST00000558464.1
ABHD17C
abhydrolase domain containing 17C, depalmitoylase
chr6_+_125790922 1.67 ENST00000453302.5
ENST00000417494.5
ENST00000392477.7
ENST00000229634.13
NCOA7
nuclear receptor coactivator 7
chr10_-_88952763 1.65 ENST00000224784.10
ACTA2
actin alpha 2, smooth muscle
chr6_+_50818857 1.65 ENST00000393655.4
TFAP2B
transcription factor AP-2 beta
chr3_-_116445458 1.64 ENST00000490035.7
LSAMP
limbic system associated membrane protein
chr11_+_59172116 1.63 ENST00000227451.4
DTX4
deltex E3 ubiquitin ligase 4
chr16_+_1706163 1.62 ENST00000250894.8
ENST00000673691.1
ENST00000356010.9
ENST00000610761.2
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr16_-_65121930 1.61 ENST00000566827.5
ENST00000394156.7
ENST00000268603.9
ENST00000562998.1
CDH11
cadherin 11
chr9_+_114155526 1.61 ENST00000356083.8
COL27A1
collagen type XXVII alpha 1 chain
chr8_-_126558461 1.58 ENST00000304916.4
LRATD2
LRAT domain containing 2
chr20_+_50731571 1.58 ENST00000371610.7
PARD6B
par-6 family cell polarity regulator beta
chr7_-_108456378 1.55 ENST00000613830.4
ENST00000413765.6
ENST00000379028.8
NRCAM
neuronal cell adhesion molecule
chr2_-_9003657 1.54 ENST00000462696.1
ENST00000305997.8
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr17_+_32486975 1.54 ENST00000313401.4
CDK5R1
cyclin dependent kinase 5 regulatory subunit 1
chr2_+_43637247 1.53 ENST00000282406.9
PLEKHH2
pleckstrin homology, MyTH4 and FERM domain containing H2
chr1_-_107965009 1.53 ENST00000527011.5
ENST00000370056.9
VAV3
vav guanine nucleotide exchange factor 3
chr20_+_36092698 1.51 ENST00000430276.5
ENST00000373950.6
ENST00000373946.7
ENST00000441639.5
ENST00000628415.2
ENST00000452261.5
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr2_+_231395702 1.50 ENST00000287590.6
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr1_-_67833448 1.50 ENST00000370982.4
GNG12
G protein subunit gamma 12
chr2_-_20012661 1.49 ENST00000421259.2
ENST00000407540.8
MATN3
matrilin 3
chr4_-_39638846 1.47 ENST00000295958.10
SMIM14
small integral membrane protein 14
chr9_+_101028721 1.46 ENST00000374874.8
PLPPR1
phospholipid phosphatase related 1
chr11_-_68121370 1.45 ENST00000265689.9
ENST00000356135.9
CHKA
choline kinase alpha
chr5_+_75337211 1.45 ENST00000287936.9
ENST00000343975.9
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr16_+_981762 1.44 ENST00000293894.4
SOX8
SRY-box transcription factor 8
chr17_+_58755821 1.40 ENST00000308249.4
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent 1E
chr1_-_149917826 1.37 ENST00000369145.1
ENST00000369146.8
SV2A
synaptic vesicle glycoprotein 2A
chr5_+_72107453 1.37 ENST00000296755.12
ENST00000511641.2
MAP1B
microtubule associated protein 1B
chr15_+_59438149 1.36 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
FAM81A
family with sequence similarity 81 member A
chr21_-_38498415 1.35 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chr9_-_86099506 1.35 ENST00000388712.7
GOLM1
golgi membrane protein 1
chr17_-_48615261 1.34 ENST00000239144.5
HOXB8
homeobox B8
chr8_+_17027230 1.34 ENST00000318063.10
MICU3
mitochondrial calcium uptake family member 3
chr12_+_67269328 1.33 ENST00000545606.6
CAND1
cullin associated and neddylation dissociated 1
chr6_+_30557287 1.33 ENST00000376560.8
PRR3
proline rich 3
chrX_-_54357993 1.33 ENST00000375169.7
ENST00000354646.6
WNK3
WNK lysine deficient protein kinase 3
chr15_+_28885955 1.31 ENST00000558402.5
ENST00000683413.1
ENST00000558330.5
APBA2
amyloid beta precursor protein binding family A member 2
chr4_+_54229261 1.31 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
PDGFRA
platelet derived growth factor receptor alpha
chr22_-_38844020 1.30 ENST00000333039.4
NPTXR
neuronal pentraxin receptor
chr3_-_9249623 1.29 ENST00000383836.8
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr21_+_31873010 1.29 ENST00000270112.7
HUNK
hormonally up-regulated Neu-associated kinase
chr3_+_123067016 1.28 ENST00000316218.12
PDIA5
protein disulfide isomerase family A member 5
chr2_-_164841410 1.28 ENST00000342193.8
ENST00000375458.6
COBLL1
cordon-bleu WH2 repeat protein like 1
chr19_-_35900532 1.27 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKBID
NFKB inhibitor delta
chr22_-_43862480 1.27 ENST00000330884.9
SULT4A1
sulfotransferase family 4A member 1
chr7_+_20330893 1.26 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr3_+_58237501 1.25 ENST00000295962.8
ABHD6
abhydrolase domain containing 6, acylglycerol lipase
chrX_-_155264471 1.25 ENST00000369454.4
RAB39B
RAB39B, member RAS oncogene family
chr5_-_180353317 1.24 ENST00000253778.13
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr12_+_31959406 1.24 ENST00000540924.5
ENST00000312561.9
RESF1
retroelement silencing factor 1
chr14_-_39432414 1.23 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr4_+_20251896 1.23 ENST00000504154.6
SLIT2
slit guidance ligand 2
chr14_-_63728027 1.21 ENST00000247225.7
SGPP1
sphingosine-1-phosphate phosphatase 1
chr15_+_32717994 1.20 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
GREM1
gremlin 1, DAN family BMP antagonist
chr7_-_81770039 1.19 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr15_-_37098281 1.19 ENST00000559085.5
ENST00000397624.7
MEIS2
Meis homeobox 2
chr10_+_110497898 1.19 ENST00000369583.4
DUSP5
dual specificity phosphatase 5
chr5_+_172641241 1.19 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr5_+_31193678 1.17 ENST00000265071.3
CDH6
cadherin 6
chr11_+_120210991 1.16 ENST00000328965.9
OAF
out at first homolog
chr2_+_191678122 1.15 ENST00000425611.9
ENST00000410026.7
NABP1
nucleic acid binding protein 1
chr10_+_58512864 1.15 ENST00000373886.8
BICC1
BicC family RNA binding protein 1
chr2_+_161416273 1.14 ENST00000389554.8
TBR1
T-box brain transcription factor 1
chr12_-_76878985 1.14 ENST00000547435.1
ENST00000552330.5
ENST00000311083.10
ENST00000546966.5
CSRP2
cysteine and glycine rich protein 2
chr4_+_110476133 1.14 ENST00000265162.10
ENPEP
glutamyl aminopeptidase
chr2_+_46297397 1.13 ENST00000263734.5
EPAS1
endothelial PAS domain protein 1
chrX_+_17375230 1.12 ENST00000380060.7
NHS
NHS actin remodeling regulator
chr17_-_52159983 1.12 ENST00000575181.1
ENST00000570565.5
ENST00000442502.6
CA10
carbonic anhydrase 10
chr12_-_120469655 1.11 ENST00000229390.8
SRSF9
serine and arginine rich splicing factor 9
chr1_+_200027702 1.09 ENST00000367362.8
NR5A2
nuclear receptor subfamily 5 group A member 2
chr6_+_127118657 1.09 ENST00000356698.9
RSPO3
R-spondin 3
chrX_-_3713593 1.09 ENST00000262848.6
PRKX
protein kinase X-linked
chr9_-_38069220 1.09 ENST00000377707.4
SHB
SH2 domain containing adaptor protein B
chr22_+_41560973 1.08 ENST00000306149.12
CSDC2
cold shock domain containing C2
chr15_+_73052449 1.07 ENST00000261908.11
NEO1
neogenin 1
chr7_-_75738930 1.05 ENST00000336926.11
ENST00000434438.6
HIP1
huntingtin interacting protein 1
chr1_-_114716729 1.05 ENST00000369535.5
NRAS
NRAS proto-oncogene, GTPase
chr8_+_75539862 1.05 ENST00000396423.4
HNF4G
hepatocyte nuclear factor 4 gamma
chr20_+_3796288 1.04 ENST00000439880.6
ENST00000245960.10
CDC25B
cell division cycle 25B
chr1_-_92961440 1.04 ENST00000370310.5
ENST00000615519.4
ENST00000613902.4
ENST00000616709.4
DIPK1A
divergent protein kinase domain 1A
chr5_+_111224374 1.03 ENST00000282356.9
CAMK4
calcium/calmodulin dependent protein kinase IV
chr8_+_28494190 1.03 ENST00000537916.2
ENST00000240093.8
ENST00000523546.1
FZD3
frizzled class receptor 3
chr4_+_183905266 1.03 ENST00000308497.9
STOX2
storkhead box 2
chr6_-_99425269 1.02 ENST00000647811.1
ENST00000481229.2
ENST00000369239.10
ENST00000681611.1
ENST00000681615.1
ENST00000438806.5
PNISR
PNN interacting serine and arginine rich protein
chr15_+_81000913 1.02 ENST00000267984.4
TLNRD1
talin rod domain containing 1
chr11_-_115504389 1.02 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
CADM1
cell adhesion molecule 1
chr18_-_34224871 1.02 ENST00000261592.10
NOL4
nucleolar protein 4
chrX_+_105822531 1.01 ENST00000243300.14
ENST00000536164.5
NRK
Nik related kinase
chr19_+_32405789 1.01 ENST00000586987.5
DPY19L3
dpy-19 like C-mannosyltransferase 3
chr21_+_43719095 1.00 ENST00000468090.5
ENST00000291565.9
PDXK
pyridoxal kinase
chr12_+_8082260 1.00 ENST00000638237.1
ENST00000339754.11
ENST00000639811.1
ENST00000639167.1
ENST00000541948.2
NECAP1
NECAP endocytosis associated 1
chr9_+_34958254 0.99 ENST00000242315.3
PHF24
PHD finger protein 24
chr15_+_97960692 0.98 ENST00000268042.7
ARRDC4
arrestin domain containing 4
chr5_-_122078249 0.96 ENST00000231004.5
LOX
lysyl oxidase
chr8_+_79611036 0.96 ENST00000220876.12
ENST00000518111.5
STMN2
stathmin 2
chr17_+_28042660 0.96 ENST00000407008.8
NLK
nemo like kinase
chr1_-_84690406 0.95 ENST00000605755.5
ENST00000342203.8
ENST00000437941.6
SSX2IP
SSX family member 2 interacting protein
chr3_+_36380477 0.95 ENST00000457375.6
ENST00000273183.8
ENST00000434649.1
STAC
SH3 and cysteine rich domain
chr14_+_32939243 0.95 ENST00000346562.6
ENST00000548645.5
ENST00000356141.8
ENST00000357798.9
NPAS3
neuronal PAS domain protein 3
chr1_-_206772484 0.93 ENST00000423557.1
IL10
interleukin 10
chr3_+_113747022 0.93 ENST00000273398.8
ENST00000496747.5
ENST00000475322.1
ATP6V1A
ATPase H+ transporting V1 subunit A
chr4_+_26860778 0.92 ENST00000467011.6
STIM2
stromal interaction molecule 2
chr1_+_192575765 0.92 ENST00000469578.2
ENST00000367459.8
RGS1
regulator of G protein signaling 1
chr18_+_22169580 0.92 ENST00000269216.10
GATA6
GATA binding protein 6
chrX_+_65488735 0.92 ENST00000338957.4
ZC3H12B
zinc finger CCCH-type containing 12B
chr12_+_109713817 0.92 ENST00000538780.2
FAM222A
family with sequence similarity 222 member A
chr2_+_31234144 0.91 ENST00000322054.10
EHD3
EH domain containing 3
chr9_+_111896804 0.91 ENST00000374279.4
UGCG
UDP-glucose ceramide glucosyltransferase
chr10_-_100519829 0.91 ENST00000370345.8
SEC31B
SEC31 homolog B, COPII coat complex component
chr16_-_68448491 0.91 ENST00000561749.1
ENST00000219334.10
SMPD3
sphingomyelin phosphodiesterase 3
chr2_-_168247569 0.91 ENST00000355999.5
STK39
serine/threonine kinase 39
chr13_+_24160705 0.91 ENST00000382108.8
SPATA13
spermatogenesis associated 13
chr5_-_38595396 0.90 ENST00000263409.8
LIFR
LIF receptor subunit alpha
chr4_-_138242325 0.90 ENST00000280612.9
SLC7A11
solute carrier family 7 member 11
chr20_+_49982969 0.89 ENST00000244050.3
SNAI1
snail family transcriptional repressor 1
chr5_-_132737518 0.89 ENST00000403231.6
ENST00000378735.5
ENST00000618515.4
ENST00000378746.8
KIF3A
kinesin family member 3A
chr16_-_22374580 0.89 ENST00000268383.7
CDR2
cerebellar degeneration related protein 2
chr17_+_40219276 0.89 ENST00000583268.1
ENST00000323571.9
WIPF2
WAS/WASL interacting protein family member 2
chr9_+_116153783 0.87 ENST00000328252.4
PAPPA
pappalysin 1
chr11_+_102110437 0.87 ENST00000282441.10
ENST00000526343.5
ENST00000537274.5
ENST00000345877.6
ENST00000615667.4
YAP1
Yes1 associated transcriptional regulator
chr9_-_19786928 0.87 ENST00000341998.6
ENST00000286344.3
SLC24A2
solute carrier family 24 member 2
chr22_-_31630825 0.87 ENST00000397500.5
PISD
phosphatidylserine decarboxylase
chr2_+_84905644 0.85 ENST00000233143.6
TMSB10
thymosin beta 10
chr9_-_89178810 0.85 ENST00000375835.9
SHC3
SHC adaptor protein 3
chr11_+_63813384 0.84 ENST00000294244.9
SPINDOC
spindlin interactor and repressor of chromatin binding
chr17_+_74987581 0.84 ENST00000337231.5
CDR2L
cerebellar degeneration related protein 2 like
chr1_+_1020068 0.84 ENST00000379370.7
ENST00000620552.4
AGRN
agrin
chr1_+_65147514 0.83 ENST00000545314.5
AK4
adenylate kinase 4
chr1_+_116909869 0.83 ENST00000393203.3
PTGFRN
prostaglandin F2 receptor inhibitor
chr4_+_5051471 0.83 ENST00000282908.10
STK32B
serine/threonine kinase 32B
chr19_+_11089446 0.83 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
LDLR
low density lipoprotein receptor
chr9_+_128068172 0.83 ENST00000373068.6
ENST00000373069.10
SLC25A25
solute carrier family 25 member 25
chr1_-_40665654 0.83 ENST00000372684.8
RIMS3
regulating synaptic membrane exocytosis 3
chr1_-_47997348 0.82 ENST00000606738.3
TRABD2B
TraB domain containing 2B
chr1_+_113390495 0.82 ENST00000307546.14
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr19_+_44748673 0.81 ENST00000164227.10
BCL3
BCL3 transcription coactivator
chr12_+_103587266 0.81 ENST00000388887.7
STAB2
stabilin 2
chr12_-_54280087 0.80 ENST00000209875.9
CBX5
chromobox 5
chr13_+_48975879 0.80 ENST00000492622.6
FNDC3A
fibronectin type III domain containing 3A
chr13_+_32586443 0.80 ENST00000315596.15
PDS5B
PDS5 cohesin associated factor B
chr8_+_133191060 0.80 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
CCN4
cellular communication network factor 4
chr3_+_141487008 0.79 ENST00000286364.9
ENST00000452898.2
RASA2
RAS p21 protein activator 2
chr22_-_37427433 0.78 ENST00000452946.1
ENST00000402918.7
ELFN2
ELFN2
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr3_+_153162196 0.78 ENST00000323534.5
RAP2B
RAP2B, member of RAS oncogene family
chr17_+_56834081 0.77 ENST00000572810.1
ENST00000284061.8
DGKE
diacylglycerol kinase epsilon
chr16_-_75433391 0.77 ENST00000566254.1
ENST00000283882.4
CFDP1
craniofacial development protein 1
chr12_-_12267003 0.76 ENST00000535731.1
ENST00000261349.9
LRP6
LDL receptor related protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.1 3.2 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.8 3.2 GO:0060435 bronchiole development(GO:0060435)
0.7 2.7 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.7 2.0 GO:0033341 regulation of collagen binding(GO:0033341)
0.6 1.9 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.5 1.6 GO:0097274 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.5 1.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.5 1.5 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.5 1.4 GO:0072034 renal vesicle induction(GO:0072034)
0.5 1.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.5 2.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.4 1.8 GO:0009956 radial pattern formation(GO:0009956)
0.4 1.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 3.0 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.4 2.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 4.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.4 1.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4 1.2 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.4 1.2 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.4 2.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 2.3 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.4 1.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.4 1.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.3 1.0 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.3 1.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.3 1.0 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.3 1.7 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.3 0.9 GO:0071650 negative regulation of interleukin-18 production(GO:0032701) negative regulation of cytokine activity(GO:0060302) negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.3 3.7 GO:0003344 pericardium morphogenesis(GO:0003344)
0.3 0.9 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.3 0.6 GO:0060738 primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.3 1.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 1.7 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 0.8 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.3 1.6 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.3 2.1 GO:0021592 fourth ventricle development(GO:0021592)
0.3 1.3 GO:0072277 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 1.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.2 1.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 0.7 GO:0071314 cellular response to cocaine(GO:0071314)
0.2 0.7 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.9 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.2 1.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 1.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 3.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 1.3 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.2 1.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 0.8 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.2 1.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 1.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 0.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 3.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 0.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 2.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 2.4 GO:0008354 germ cell migration(GO:0008354)
0.2 0.8 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 1.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.2 1.7 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.4 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 1.0 GO:0021764 amygdala development(GO:0021764)
0.1 1.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 3.2 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 0.7 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.4 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 4.4 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.1 1.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 3.3 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 2.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.5 GO:2000703 regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734)
0.1 2.8 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.7 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 1.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.6 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 1.0 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 1.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.5 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 0.8 GO:0003383 apical constriction(GO:0003383)
0.1 0.5 GO:0002880 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1 1.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.2 GO:0002339 B cell selection(GO:0002339)
0.1 0.3 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 1.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.8 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 1.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.7 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) regulation of forebrain neuron differentiation(GO:2000977)
0.1 0.7 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.3 GO:1900450 negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782)
0.1 0.3 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.1 0.6 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.5 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 1.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.4 GO:0060242 contact inhibition(GO:0060242)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 2.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.6 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.1 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 1.0 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.7 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.8 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.8 GO:0015866 ADP transport(GO:0015866)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 1.0 GO:0007144 female meiosis I(GO:0007144)
0.1 0.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.2 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 1.9 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.2 GO:0070428 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 1.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 1.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913)
0.0 0.7 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.7 GO:0021794 thalamus development(GO:0021794)
0.0 0.0 GO:0048377 lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 1.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 1.1 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807) somite rostral/caudal axis specification(GO:0032525)
0.0 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.3 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 1.4 GO:0007625 grooming behavior(GO:0007625)
0.0 0.1 GO:0072560 type B pancreatic cell maturation(GO:0072560)
0.0 0.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.5 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0015798 myo-inositol transport(GO:0015798)
0.0 1.9 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 1.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.7 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.9 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.5 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.3 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 1.3 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.5 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 2.2 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 1.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.5 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.9 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 1.0 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.4 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.2 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.9 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 1.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 2.1 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 2.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 2.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 1.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 1.7 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.8 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.0 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.6 2.3 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.6 1.7 GO:0060187 cell pole(GO:0060187)
0.4 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.4 1.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 2.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.3 1.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 2.1 GO:0097513 myosin II filament(GO:0097513)
0.3 0.9 GO:0016939 kinesin II complex(GO:0016939)
0.3 0.8 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.3 2.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 0.7 GO:0009346 citrate lyase complex(GO:0009346)
0.2 0.8 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.9 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.2 1.2 GO:0070876 SOSS complex(GO:0070876)
0.2 3.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.2 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.2 0.5 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.4 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 1.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.9 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 1.4 GO:0001940 male pronucleus(GO:0001940)
0.1 0.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 2.1 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 3.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.5 GO:0071953 elastic fiber(GO:0071953)
0.1 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 3.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.6 GO:0042587 glycogen granule(GO:0042587)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 1.0 GO:0010369 chromocenter(GO:0010369)
0.0 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.7 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.8 GO:0005605 basal lamina(GO:0005605)
0.0 2.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0030120 vesicle coat(GO:0030120)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 4.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.3 GO:0043296 apical junction complex(GO:0043296)
0.0 4.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.9 GO:0030315 T-tubule(GO:0030315)
0.0 1.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.1 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.6 GO:0005903 brush border(GO:0005903)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.0 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.0 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.7 2.7 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.6 1.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.5 3.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.5 1.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.4 1.5 GO:0033265 choline binding(GO:0033265)
0.4 1.4 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.3 3.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 0.8 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.3 1.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 1.0 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.3 0.8 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 0.7 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.2 2.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 2.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.9 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 1.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 1.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.8 GO:0043237 laminin-1 binding(GO:0043237)
0.2 0.6 GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.2 1.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 0.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.9 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2 3.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 0.7 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 0.7 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.2 2.9 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 3.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.7 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.7 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.8 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.7 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 5.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 3.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 1.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.0 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 1.2 GO:0016015 morphogen activity(GO:0016015)
0.1 0.9 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.3 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 5.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 1.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 3.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.5 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.3 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 2.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 2.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.3 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 1.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 1.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 1.9 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 2.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 5.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 2.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 2.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 2.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.9 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 3.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.3 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 3.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 5.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 6.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 2.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 8.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 5.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 7.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 6.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 0.7 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 4.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 1.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 4.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.8 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 2.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 4.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 3.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 3.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE