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Illumina Body Map 2 (GSE30611)
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Results for UCACAUU
Z-value: 0.66
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miRNA associated with seed UCACAUU
Network of associatons between targets according to the STRING database.
First level regulatory network of UCACAUU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.5 | 1.4 | GO:2000417 | negative regulation of eosinophil migration(GO:2000417) |
| 0.1 | 1.4 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.0 | 1.4 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.1 | 1.3 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 1.3 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 0.0 | 1.2 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.4 | 1.1 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 0.1 | 1.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.2 | 1.0 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 1.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 1.0 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 0.9 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 0.7 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.0 | 0.6 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.6 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.4 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.1 | 1.4 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 1.3 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 1.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.4 | 1.1 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.2 | 1.1 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.3 | 1.0 | GO:0031696 | alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696) |
| 0.3 | 0.9 | GO:0070123 | transforming growth factor beta receptor activity, type III(GO:0070123) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.7 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.4 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.2 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 1.1 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.6 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.0 | 0.6 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 1.3 | REACTOME TRAF6 MEDIATED NFKB ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.0 | 1.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 1.2 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 1.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 1.0 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.8 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 0.7 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.6 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.6 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |