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Illumina Body Map 2 (GSE30611)
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Results for UGCAUAG
Z-value: 0.80
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miRNA associated with seed UGCAUAG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-153-3p
|
MIMAT0000439 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_10218808 Show fit | 3.77 |
ENST00000254976.7
ENST00000304886.6 |
synaptosome associated protein 25 |
|
| chr3_+_111998739 Show fit | 3.21 |
ENST00000393917.6
ENST00000273368.8 |
transgelin 3 |
|
| chr1_+_237042176 Show fit | 3.12 |
ENST00000366574.7
|
ryanodine receptor 2 |
|
| chr8_+_24914942 Show fit | 3.10 |
ENST00000433454.3
|
neurofilament medium |
|
| chr3_+_84958963 Show fit | 2.88 |
ENST00000383699.8
|
cell adhesion molecule 2 |
|
| chr10_-_20897288 Show fit | 2.68 |
ENST00000377122.9
|
nebulette |
|
| chr20_+_9514562 Show fit | 2.55 |
ENST00000246070.3
|
lysosomal associated membrane protein family member 5 |
|
| chr18_-_43277482 Show fit | 2.52 |
ENST00000255224.8
ENST00000590752.5 ENST00000596867.1 |
synaptotagmin 4 |
|
| chr4_-_89837106 Show fit | 2.37 |
ENST00000394986.5
ENST00000394991.8 ENST00000506244.5 ENST00000394989.6 ENST00000673902.1 ENST00000674129.1 |
synuclein alpha |
|
| chr6_+_44270434 Show fit | 2.17 |
ENST00000451188.7
|
transmembrane protein 151B |
Network of associatons between targets according to the STRING database.
First level regulatory network of UGCAUAG
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 24.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.9 | 3.8 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.8 | 3.1 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.6 | 3.1 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 0.9 | 2.7 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.2 | 2.5 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.4 | 2.4 | GO:1903285 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.5 | 2.2 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 0.0 | 2.1 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.0 | 2.1 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.6 | 4.5 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.1 | 4.2 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 3.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 3.9 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.2 | 3.8 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 3.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.2 | 3.1 | GO:0005883 | neurofilament(GO:0005883) |
| 0.9 | 2.7 | GO:0099569 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 0.0 | 2.6 | GO:0031902 | late endosome membrane(GO:0031902) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 18.1 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 6.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 4.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.4 | 4.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 4.0 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 3.5 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.7 | 3.4 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.1 | 3.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 2.9 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.4 | 2.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 2.3 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 2.1 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.8 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 1.6 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.9 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.8 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.8 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.7 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 0.6 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.1 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.1 | 4.4 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 3.4 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 3.1 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 2.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.5 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 2.5 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 1.6 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 1.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 1.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |