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Illumina Body Map 2 (GSE30611)

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Results for VAX2_RHOXF2

Z-value: 1.06

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Transcription factors associated with VAX2_RHOXF2

Gene Symbol Gene ID Gene Info
VAX2
ENSG00000116035.4 ventral anterior homeobox 2
RHOXF2
ENSG00000131721.6 Rhox homeobox family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RHOXF2hg38_v1_chrX_+_120158600_120158624-0.513.0e-03Click!
VAX2hg38_v1_chr2_+_70900546_709006170.154.3e-01Click!

Activity profile of VAX2_RHOXF2 motif

Sorted Z-values of VAX2_RHOXF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_122370523 4.18 ENST00000643810.1
ENST00000540753.6
PTGS1
prostaglandin-endoperoxide synthase 1
chr9_+_122371014 4.15 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr9_+_122371036 4.10 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr16_+_72054477 4.09 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
HP
haptoglobin
chr16_-_55833085 3.07 ENST00000360526.8
CES1
carboxylesterase 1
chr16_-_55833186 3.07 ENST00000361503.8
ENST00000422046.6
CES1
carboxylesterase 1
chr20_+_57561103 2.79 ENST00000319441.6
PCK1
phosphoenolpyruvate carboxykinase 1
chr2_-_88947820 2.56 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr6_+_26365159 2.55 ENST00000532865.5
ENST00000396934.7
ENST00000508906.6
ENST00000530653.5
ENST00000527417.5
BTN3A2
butyrophilin subfamily 3 member A2
chr6_+_26365215 2.48 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
BTN3A2
butyrophilin subfamily 3 member A2
chr4_-_185775271 2.38 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
SORBS2
sorbin and SH3 domain containing 2
chr6_+_26365176 2.19 ENST00000377708.7
BTN3A2
butyrophilin subfamily 3 member A2
chr2_+_90038848 2.13 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr5_+_132873660 2.09 ENST00000296877.3
LEAP2
liver enriched antimicrobial peptide 2
chr6_+_29550407 2.07 ENST00000641137.1
OR2I1P
olfactory receptor family 2 subfamily I member 1 pseudogene
chr3_+_157436842 1.91 ENST00000295927.4
PTX3
pentraxin 3
chr2_-_89177160 1.91 ENST00000484817.1
IGKV2-24
immunoglobulin kappa variable 2-24
chr4_-_185775411 1.87 ENST00000445115.5
ENST00000451701.5
SORBS2
sorbin and SH3 domain containing 2
chr6_+_26402237 1.85 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
BTN3A1
butyrophilin subfamily 3 member A1
chr6_+_26402289 1.80 ENST00000414912.2
BTN3A1
butyrophilin subfamily 3 member A1
chr4_+_168497044 1.63 ENST00000505667.6
PALLD
palladin, cytoskeletal associated protein
chr4_+_168497066 1.63 ENST00000261509.10
PALLD
palladin, cytoskeletal associated protein
chr4_+_150582119 1.60 ENST00000317605.6
MAB21L2
mab-21 like 2
chr9_-_92404559 1.57 ENST00000262551.8
ENST00000375561.10
OGN
osteoglycin
chr1_+_162366896 1.56 ENST00000420220.1
ENSG00000254706.3
novel protein
chr6_+_130018565 1.42 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr2_+_90220727 1.42 ENST00000471857.2
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr4_-_25863537 1.36 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L3
SEL1L family member 3
chr19_+_49513353 1.33 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr17_-_42185452 1.31 ENST00000293330.1
HCRT
hypocretin neuropeptide precursor
chr16_+_72063226 1.20 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
HPR
haptoglobin-related protein
chr1_-_92486916 1.18 ENST00000294702.6
GFI1
growth factor independent 1 transcriptional repressor
chr4_-_185775432 1.18 ENST00000457247.5
ENST00000435480.5
ENST00000425679.5
ENST00000457934.5
SORBS2
sorbin and SH3 domain containing 2
chr4_-_185775376 1.17 ENST00000456596.5
ENST00000414724.5
SORBS2
sorbin and SH3 domain containing 2
chr6_+_106360668 1.15 ENST00000633556.3
CRYBG1
crystallin beta-gamma domain containing 1
chr7_+_116222804 1.13 ENST00000393481.6
TES
testin LIM domain protein
chr12_+_16347102 1.08 ENST00000536371.5
ENST00000010404.6
MGST1
microsomal glutathione S-transferase 1
chr12_+_16347665 1.04 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
MGST1
microsomal glutathione S-transferase 1
chr4_+_87975667 1.03 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
SPP1
secreted phosphoprotein 1
chr1_+_34792990 1.03 ENST00000450137.1
ENST00000342280.5
GJA4
gap junction protein alpha 4
chr9_-_19149278 1.01 ENST00000434144.5
PLIN2
perilipin 2
chr10_+_72893734 1.00 ENST00000334011.10
OIT3
oncoprotein induced transcript 3
chr14_+_22096017 1.00 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr12_+_130953898 0.99 ENST00000261654.10
ADGRD1
adhesion G protein-coupled receptor D1
chr5_+_172641241 0.98 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr12_+_16347637 0.96 ENST00000543076.5
ENST00000396210.8
MGST1
microsomal glutathione S-transferase 1
chr4_-_73620391 0.94 ENST00000395777.6
ENST00000307439.10
RASSF6
Ras association domain family member 6
chr1_-_113871665 0.91 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
PTPN22
protein tyrosine phosphatase non-receptor type 22
chrX_+_136648138 0.89 ENST00000370629.7
CD40LG
CD40 ligand
chr8_-_100649660 0.85 ENST00000311812.7
SNX31
sorting nexin 31
chr6_-_132714045 0.81 ENST00000367928.5
VNN1
vanin 1
chr8_-_33567118 0.79 ENST00000256257.2
RNF122
ring finger protein 122
chr7_+_73830988 0.78 ENST00000340958.4
CLDN4
claudin 4
chr7_+_100119607 0.76 ENST00000262932.5
CNPY4
canopy FGF signaling regulator 4
chr4_+_87975829 0.75 ENST00000614857.5
SPP1
secreted phosphoprotein 1
chr4_-_73620629 0.73 ENST00000342081.7
RASSF6
Ras association domain family member 6
chr15_+_58410543 0.73 ENST00000356113.10
ENST00000414170.7
LIPC
lipase C, hepatic type
chr20_-_35147285 0.71 ENST00000374491.3
ENST00000374492.8
EDEM2
ER degradation enhancing alpha-mannosidase like protein 2
chr12_-_9869345 0.70 ENST00000228438.3
CLEC2B
C-type lectin domain family 2 member B
chrX_+_136648214 0.67 ENST00000370628.2
CD40LG
CD40 ligand
chr16_+_11965193 0.67 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr6_+_26440472 0.65 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
BTN3A3
butyrophilin subfamily 3 member A3
chr2_-_189179754 0.63 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr15_-_37101205 0.63 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
MEIS2
Meis homeobox 2
chrX_+_43656289 0.61 ENST00000338702.4
MAOA
monoamine oxidase A
chr7_+_50308672 0.60 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKZF1
IKAROS family zinc finger 1
chr21_-_36542600 0.60 ENST00000399136.5
CLDN14
claudin 14
chr10_+_18260715 0.60 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr19_-_45584769 0.60 ENST00000263275.5
OPA3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr2_+_89884740 0.59 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr4_-_67963441 0.59 ENST00000508048.6
TMPRSS11A
transmembrane serine protease 11A
chr3_+_158801926 0.58 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
MFSD1
major facilitator superfamily domain containing 1
chr7_+_142300924 0.58 ENST00000455382.2
TRBV2
T cell receptor beta variable 2
chr14_+_21997531 0.58 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr10_+_97446137 0.56 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr4_-_137532452 0.55 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr2_-_40453438 0.55 ENST00000455476.5
SLC8A1
solute carrier family 8 member A1
chr10_+_97446194 0.55 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
ZDHHC16
zinc finger DHHC-type palmitoyltransferase 16
chr1_-_56579555 0.54 ENST00000371250.4
PLPP3
phospholipid phosphatase 3
chr15_+_73926443 0.53 ENST00000261921.8
LOXL1
lysyl oxidase like 1
chr3_-_151316795 0.52 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr5_+_177384430 0.48 ENST00000512593.5
ENST00000324417.6
SLC34A1
solute carrier family 34 member 1
chr7_-_44541262 0.47 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr4_-_73620500 0.47 ENST00000335049.5
RASSF6
Ras association domain family member 6
chr4_+_40200320 0.46 ENST00000511121.5
RHOH
ras homolog family member H
chrX_-_155071064 0.45 ENST00000369484.8
ENST00000369476.8
CMC4
MTCP1
C-X9-C motif containing 4
mature T cell proliferation 1
chr15_+_49170237 0.43 ENST00000560031.6
ENST00000558145.5
ENST00000544523.5
ENST00000560138.5
GALK2
galactokinase 2
chr16_-_28597042 0.42 ENST00000533150.5
ENST00000335715.9
SULT1A2
sulfotransferase family 1A member 2
chr4_-_106368772 0.41 ENST00000638719.4
GIMD1
GIMAP family P-loop NTPase domain containing 1
chr12_+_64405046 0.38 ENST00000540203.5
XPOT
exportin for tRNA
chr2_+_90209873 0.37 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr15_+_49170200 0.36 ENST00000396509.6
GALK2
galactokinase 2
chr11_-_31509569 0.35 ENST00000526776.5
IMMP1L
inner mitochondrial membrane peptidase subunit 1
chr4_+_168497113 0.35 ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr15_+_58138368 0.35 ENST00000219919.9
ENST00000536493.1
AQP9
aquaporin 9
chr2_-_89297785 0.34 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr15_+_58138169 0.34 ENST00000558772.5
AQP9
aquaporin 9
chr12_-_21910853 0.34 ENST00000544039.5
ABCC9
ATP binding cassette subfamily C member 9
chr7_-_100119291 0.33 ENST00000431404.2
TAF6
TATA-box binding protein associated factor 6
chr9_-_5339874 0.33 ENST00000223862.2
RLN1
relaxin 1
chr4_-_40475749 0.33 ENST00000507180.5
RBM47
RNA binding motif protein 47
chr6_-_137173644 0.31 ENST00000296980.7
ENST00000349184.8
ENST00000339602.3
IL22RA2
interleukin 22 receptor subunit alpha 2
chr11_-_117876683 0.30 ENST00000530956.6
FXYD6
FXYD domain containing ion transport regulator 6
chr7_-_44541318 0.29 ENST00000381160.8
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr7_-_111392915 0.29 ENST00000450877.5
IMMP2L
inner mitochondrial membrane peptidase subunit 2
chr5_-_150449676 0.29 ENST00000312037.6
RPS14
ribosomal protein S14
chr12_+_26195647 0.28 ENST00000535504.1
SSPN
sarcospan
chr5_-_150449696 0.27 ENST00000401695.8
RPS14
ribosomal protein S14
chr8_-_96261579 0.27 ENST00000517720.1
ENST00000523821.5
ENST00000287025.4
MTERF3
mitochondrial transcription termination factor 3
chr11_-_117876892 0.26 ENST00000539526.5
FXYD6
FXYD domain containing ion transport regulator 6
chr14_+_22202561 0.25 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr19_+_24033399 0.24 ENST00000664647.1
ENST00000656993.1
ENST00000666101.1
ENST00000613065.4
ENSG00000268362.6
ZNF254
novel transcript
zinc finger protein 254
chr12_-_50249883 0.24 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr7_-_101217569 0.24 ENST00000223127.8
PLOD3
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr6_-_82247697 0.23 ENST00000306270.12
ENST00000610980.4
IBTK
inhibitor of Bruton tyrosine kinase
chr2_-_213151590 0.23 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKZF2
IKAROS family zinc finger 2
chr2_+_102473219 0.22 ENST00000295269.5
SLC9A4
solute carrier family 9 member A4
chrX_+_73563190 0.22 ENST00000373504.10
ENST00000373502.9
CHIC1
cysteine rich hydrophobic domain 1
chr11_-_117876719 0.21 ENST00000529335.6
ENST00000260282.8
FXYD6
FXYD domain containing ion transport regulator 6
chr1_+_160400543 0.21 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr17_+_50746534 0.21 ENST00000511974.5
LUC7L3
LUC7 like 3 pre-mRNA splicing factor
chr5_+_174724549 0.21 ENST00000239243.7
ENST00000507785.2
MSX2
msh homeobox 2
chr17_-_41047267 0.21 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr19_-_3557563 0.20 ENST00000389395.7
ENST00000355415.7
MFSD12
major facilitator superfamily domain containing 12
chr21_-_7793954 0.20 ENST00000624951.1
SMIM34B
small integral membrane protein 34B
chr12_+_55444069 0.19 ENST00000641516.1
ENST00000641202.1
OR6C2
olfactory receptor family 6 subfamily C member 2
chr11_+_124183219 0.19 ENST00000641351.2
OR10D3
olfactory receptor family 10 subfamily D member 3
chr4_-_68245683 0.18 ENST00000332644.6
TMPRSS11B
transmembrane serine protease 11B
chr14_+_61187544 0.17 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
PRKCH
protein kinase C eta
chr9_+_72577788 0.17 ENST00000645208.2
TMC1
transmembrane channel like 1
chr9_-_134068012 0.17 ENST00000303407.12
BRD3
bromodomain containing 3
chr17_+_74935892 0.15 ENST00000328801.6
OTOP3
otopetrin 3
chr9_+_72577369 0.15 ENST00000651183.1
TMC1
transmembrane channel like 1
chr11_-_117877463 0.14 ENST00000527717.5
FXYD6
FXYD domain containing ion transport regulator 6
chr9_+_12693327 0.14 ENST00000388918.10
TYRP1
tyrosinase related protein 1
chr14_-_21526202 0.14 ENST00000450879.2
SALL2
spalt like transcription factor 2
chr5_+_67004618 0.13 ENST00000261569.11
ENST00000436277.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_29099490 0.13 ENST00000641659.2
OR2J1
olfactory receptor family 2 subfamily J member 1
chr21_-_34423951 0.13 ENST00000450895.2
SMIM34A
small integral membrane protein 34A
chr20_-_51802433 0.12 ENST00000395997.3
SALL4
spalt like transcription factor 4
chr17_-_40799939 0.12 ENST00000306658.8
KRT28
keratin 28
chr3_+_42979281 0.12 ENST00000488863.5
ENST00000430121.3
GASK1A
golgi associated kinase 1A
chr6_-_138545685 0.10 ENST00000342260.9
NHSL1
NHS like 1
chr6_+_49499916 0.10 ENST00000371197.9
GLYATL3
glycine-N-acyltransferase like 3
chr10_+_70052582 0.10 ENST00000676699.1
MACROH2A2
macroH2A.2 histone
chr19_-_51804104 0.10 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr11_-_122116215 0.10 ENST00000560104.2
BLID
BH3-like motif containing, cell death inducer
chr18_-_69956924 0.08 ENST00000581982.5
ENST00000280200.8
CD226
CD226 molecule
chr5_+_121961955 0.08 ENST00000339397.5
SRFBP1
serum response factor binding protein 1
chr18_+_49561013 0.07 ENST00000583083.1
LIPG
lipase G, endothelial type
chr1_-_17439657 0.06 ENST00000375436.9
RCC2
regulator of chromosome condensation 2
chr7_-_44082464 0.06 ENST00000335195.10
ENST00000395831.7
ENST00000414235.5
ENST00000242248.10
ENST00000452049.1
POLM
DNA polymerase mu
chr14_-_52791597 0.05 ENST00000216410.8
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr15_+_101812202 0.05 ENST00000332238.5
OR4F15
olfactory receptor family 4 subfamily F member 15
chr12_+_119668109 0.05 ENST00000229328.10
ENST00000630317.1
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr14_+_20455210 0.04 ENST00000557344.5
ENST00000216714.8
ENST00000398030.8
ENST00000557181.5
ENST00000555839.5
ENST00000553368.1
ENST00000556054.5
ENST00000557054.1
ENST00000557592.5
ENST00000557150.5
APEX1
apurinic/apyrimidinic endodeoxyribonuclease 1
chr12_-_10802627 0.04 ENST00000240687.2
TAS2R7
taste 2 receptor member 7
chr18_+_34976928 0.04 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
MAPRE2
microtubule associated protein RP/EB family member 2
chr10_+_18400562 0.03 ENST00000377315.5
ENST00000650685.1
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr11_-_62754141 0.03 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
ZBTB3
zinc finger and BTB domain containing 3
chr11_-_5301946 0.01 ENST00000380224.2
OR51B4
olfactory receptor family 51 subfamily B member 4
chr6_+_49499965 0.01 ENST00000545705.1
GLYATL3
glycine-N-acyltransferase like 3
chr18_-_69956670 0.01 ENST00000583955.5
CD226
CD226 molecule
chr12_+_77966204 0.00 ENST00000550503.1
NAV3
neuron navigator 3
chr8_+_7926337 0.00 ENST00000400120.3
ZNF705B
zinc finger protein 705B

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
1.4 4.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.0 3.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.9 2.8 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.6 1.9 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.6 12.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 1.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.4 1.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 1.8 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.3 11.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.7 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 1.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 0.5 GO:2000118 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.7 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.5 GO:0018277 protein deamination(GO:0018277)
0.1 3.6 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 5.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 1.0 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.2 GO:0051795 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795)
0.0 1.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:0008354 germ cell migration(GO:0008354)
0.0 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 9.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.6 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.9 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.8 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 1.0 GO:0048265 response to pain(GO:0048265)
0.0 2.1 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.2 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.1 12.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 1.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 3.6 GO:0002102 podosome(GO:0002102)
0.0 4.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 6.8 GO:0030018 Z disc(GO:0030018)
0.0 1.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 6.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.6 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.2 6.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.9 2.8 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.8 5.3 GO:0030492 hemoglobin binding(GO:0030492)
0.5 1.6 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.3 0.8 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 1.9 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 3.1 GO:0043295 glutathione binding(GO:0043295)
0.1 6.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.1 3.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 8.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 13.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions