ISMARA results: XBP1

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Illumina Body Map 2 (GSE30611)

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Results for XBP1

Z-value: 1.67

Motif logo

Transcription factors associated with XBP1

Gene Symbol	Gene ID	Gene Info
XBP1 Ensembl NCBI GeneCards UniProt	ENSG00000100219.16	X-box binding protein 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
XBP1	hg38_v1_chr22_-_28800558_28800597	0.52	2.5e-03	Click!

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_94394886 Show fit	14.47	ENST00000297268.11 ENST00000620463.1	COL1A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type I alpha 2 chain
chr22_+_38468036 Show fit	5.59	ENST00000409006.3 ENST00000216014.9	KDELR3 Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 3
chr19_+_49527988 Show fit	5.51	ENST00000270645.8	RCN3 Ensembl NCBI GeneCards UniProt Show fit	reticulocalbin 3
chr5_-_122078249 Show fit	5.49	ENST00000231004.5	LOX Ensembl NCBI GeneCards UniProt Show fit	lysyl oxidase
chr7_-_27143672 Show fit	4.60	ENST00000222726.4	HOXA5 Ensembl NCBI GeneCards UniProt Show fit	homeobox A5
chr10_+_87659839 Show fit	4.50	ENST00000456849.2	PAPSS2 Ensembl NCBI GeneCards UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr20_-_17682060 Show fit	4.36	ENST00000455029.3	RRBP1 Ensembl NCBI GeneCards UniProt Show fit	ribosome binding protein 1
chr14_-_105987068 Show fit	3.47	ENST00000390594.3	IGHV1-2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-2
chr4_+_8269744 Show fit	3.34	ENST00000307358.7 ENST00000382512.3	HTRA3 Ensembl NCBI GeneCards UniProt Show fit	HtrA serine peptidase 3
chr3_-_57597325 Show fit	3.11	ENST00000496292.5 ENST00000489843.1 ENST00000303436.11	ARF4 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr6_+_33200820 Show fit	3.03	ENST00000374675.7	SLC39A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 7
chr6_+_131808011 Show fit	3.00	ENST00000647893.1	ENPP1 Ensembl NCBI GeneCards UniProt Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr6_+_33200860 Show fit	2.86	ENST00000374677.8	SLC39A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 7
chr7_+_16753731 Show fit	2.81	ENST00000262067.5	TSPAN13 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 13
chr12_-_98644733 Show fit	2.79	ENST00000299157.5 ENST00000393042.3	IKBIP Ensembl NCBI GeneCards UniProt Show fit	IKBKB interacting protein
chr3_+_172040554 Show fit	2.69	ENST00000336824.8 ENST00000423424.5	FNDC3B Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3B
chr3_-_57597443 Show fit	2.68	ENST00000463880.1	ARF4 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr4_-_118836067 Show fit	2.66	ENST00000280551.11	SEC24D Ensembl NCBI GeneCards UniProt Show fit	SEC24 homolog D, COPII coat complex component
chr4_+_42397473 Show fit	2.65	ENST00000319234.5	SHISA3 Ensembl NCBI GeneCards UniProt Show fit	shisa family member 3
chr20_-_17682234 Show fit	2.62	ENST00000377813.6 ENST00000377807.6 ENST00000360807.8 ENST00000398782.2	RRBP1 Ensembl NCBI GeneCards UniProt Show fit	ribosome binding protein 1
chr5_-_2751670 Show fit	2.59	ENST00000302057.6	IRX2 Ensembl NCBI GeneCards UniProt Show fit	iroquois homeobox 2
chr17_-_42423246 Show fit	2.58	ENST00000357037.6	CAVIN1 Ensembl NCBI GeneCards UniProt Show fit	caveolae associated protein 1
chr19_-_4670331 Show fit	2.44	ENST00000262947.8 ENST00000599630.1	MYDGF Ensembl NCBI GeneCards UniProt Show fit	myeloid derived growth factor
chrX_+_153794635 Show fit	2.42	ENST00000370086.8 ENST00000370085.3	SSR4 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 4
chr5_-_2751648 Show fit	2.41	ENST00000382611.10	IRX2 Ensembl NCBI GeneCards UniProt Show fit	iroquois homeobox 2
chr15_-_60398733 Show fit	2.39	ENST00000559818.6	ANXA2 Ensembl NCBI GeneCards UniProt Show fit	annexin A2
chr1_+_21509415 Show fit	2.37	ENST00000374840.8 ENST00000539907.5 ENST00000540617.5	ALPL Ensembl NCBI GeneCards UniProt Show fit	alkaline phosphatase, biomineralization associated
chrX_+_153794152 Show fit	2.34	ENST00000370087.5	SSR4 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 4
chr6_+_33200409 Show fit	2.33	ENST00000444757.5	SLC39A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 7
chr19_+_48965304 Show fit	2.27	ENST00000331825.11	FTL Ensembl NCBI GeneCards UniProt Show fit	ferritin light chain
chr6_+_41638438 Show fit	2.27	ENST00000441667.5 ENST00000230321.11 ENST00000373050.8 ENST00000446650.1 ENST00000435476.1	MDFI Ensembl NCBI GeneCards UniProt Show fit	MyoD family inhibitor
chr14_-_106771020 Show fit	2.17	ENST00000617374.2	IGHV2-70 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 2-70
chr8_+_103372388 Show fit	2.07	ENST00000520337.1	CTHRC1 Ensembl NCBI GeneCards UniProt Show fit	collagen triple helix repeat containing 1
chr11_-_119101814 Show fit	2.02	ENST00000682791.1 ENST00000639704.1 ENST00000354202.9	DPAGT1 Ensembl NCBI GeneCards UniProt Show fit	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr4_-_118836167 Show fit	2.02	ENST00000419654.6	SEC24D Ensembl NCBI GeneCards UniProt Show fit	SEC24 homolog D, COPII coat complex component
chr15_+_79311084 Show fit	2.01	ENST00000299705.10	TMED3 Ensembl NCBI GeneCards UniProt Show fit	transmembrane p24 trafficking protein 3
chr6_+_147508645 Show fit	1.99	ENST00000367474.2	SAMD5 Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 5
chr19_+_16077006 Show fit	1.97	ENST00000586833.7 ENST00000642221.1	TPM4 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 4
chr3_+_128052390 Show fit	1.97	ENST00000481210.5 ENST00000243253.8	SEC61A1 Ensembl NCBI GeneCards UniProt Show fit	SEC61 translocon subunit alpha 1
chr5_-_10761156 Show fit	1.93	ENST00000432074.2 ENST00000230895.11	DAP Ensembl NCBI GeneCards UniProt Show fit	death associated protein
chr11_+_17276708 Show fit	1.91	ENST00000531172.5 ENST00000529010.6 ENST00000533738.6 ENST00000323688.10	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chr1_-_8026283 Show fit	1.90	ENST00000474874.5 ENST00000469499.5 ENST00000377482.10	ERRFI1 Ensembl NCBI GeneCards UniProt Show fit	ERBB receptor feedback inhibitor 1
chr11_+_32091065 Show fit	1.88	ENST00000054950.4	RCN1 Ensembl NCBI GeneCards UniProt Show fit	reticulocalbin 1
chr3_-_128052166 Show fit	1.84	ENST00000648300.1	MGLL Ensembl NCBI GeneCards UniProt Show fit	monoglyceride lipase
chr12_+_106955719 Show fit	1.80	ENST00000548125.5	TMEM263 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 263
chr4_-_82429386 Show fit	1.77	ENST00000507721.5	HNRNPDL Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein D like
chr12_+_56230652 Show fit	1.73	ENST00000266980.8 ENST00000437277.1	SLC39A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 5
chr1_-_23799561 Show fit	1.70	ENST00000445705.1	GALE Ensembl NCBI GeneCards UniProt Show fit	UDP-galactose-4-epimerase
chr2_-_69387241 Show fit	1.68	ENST00000361060.5	GFPT1 Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr7_-_128405930 Show fit	1.67	ENST00000470772.5 ENST00000480861.5 ENST00000496200.5	IMPDH1 Ensembl NCBI GeneCards UniProt Show fit	inosine monophosphate dehydrogenase 1
chr2_+_241315223 Show fit	1.63	ENST00000428282.5 ENST00000360051.7	SEPTIN2 Ensembl NCBI GeneCards UniProt Show fit	septin 2
chr6_-_83193207 Show fit	1.63	ENST00000652468.1 ENST00000512866.5 ENST00000616566.5 ENST00000510258.1 ENST00000650642.1 ENST00000513973.6 ENST00000503094.1 ENST00000283977.9 ENST00000509219.2 ENST00000651425.1 ENST00000508748.5	PGM3 Ensembl NCBI GeneCards UniProt Show fit	phosphoglucomutase 3
chr5_-_9546066 Show fit	1.63	ENST00000382496.10 ENST00000652226.1	SEMA5A Ensembl NCBI GeneCards UniProt Show fit	semaphorin 5A
chr3_-_128650800 Show fit	1.62	ENST00000296255.8	RPN1 Ensembl NCBI GeneCards UniProt Show fit	ribophorin I
chr3_+_33114033 Show fit	1.61	ENST00000449224.1	CRTAP Ensembl NCBI GeneCards UniProt Show fit	cartilage associated protein
chr2_-_20051610 Show fit	1.60	ENST00000175091.5	LAPTM4A Ensembl NCBI GeneCards UniProt Show fit	lysosomal protein transmembrane 4 alpha
chr13_+_45464901 Show fit	1.60	ENST00000349995.10	COG3 Ensembl NCBI GeneCards UniProt Show fit	component of oligomeric golgi complex 3
chr19_+_49528290 Show fit	1.59	ENST00000597801.1	RCN3 Ensembl NCBI GeneCards UniProt Show fit	reticulocalbin 3
chr2_-_69387188 Show fit	1.59	ENST00000674507.1 ENST00000357308.9	GFPT1 Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr2_-_110115811 Show fit	1.58	ENST00000272462.3	MALL Ensembl NCBI GeneCards UniProt Show fit	mal, T cell differentiation protein like
chr14_+_99793375 Show fit	1.57	ENST00000262233.11 ENST00000556714.5	EML1 Ensembl NCBI GeneCards UniProt Show fit	EMAP like 1
chr20_+_33007695 Show fit	1.56	ENST00000170150.4	BPIFB2 Ensembl NCBI GeneCards UniProt Show fit	BPI fold containing family B member 2
chr9_+_111631300 Show fit	1.56	ENST00000313525.4	DNAJC25 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C25
chr14_+_99793329 Show fit	1.53	ENST00000334192.8	EML1 Ensembl NCBI GeneCards UniProt Show fit	EMAP like 1
chr8_-_38269116 Show fit	1.52	ENST00000529359.5	PLPP5 Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 5
chr8_-_63026179 Show fit	1.48	ENST00000677919.1	GGH Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyl hydrolase
chr7_-_6484057 Show fit	1.48	ENST00000490996.1 ENST00000258739.9 ENST00000436575.5	KDELR2 Ensembl NCBI GeneCards UniProt Show fit DAGLB Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 2 diacylglycerol lipase beta
chr8_-_38269157 Show fit	1.45	ENST00000531823.5 ENST00000534339.5 ENST00000524616.5 ENST00000422581.6 ENST00000424479.7 ENST00000419686.2	PLPP5 Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 5
chr11_+_17276975 Show fit	1.44	ENST00000529313.5	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chr11_-_207221 Show fit	1.39	ENST00000486280.1 ENST00000332865.10 ENST00000529614.6 ENST00000325147.13 ENST00000410108.5 ENST00000382762.7	BET1L Ensembl NCBI GeneCards UniProt Show fit	Bet1 golgi vesicular membrane trafficking protein like
chr6_-_109381739 Show fit	1.34	ENST00000504373.2	CD164 Ensembl NCBI GeneCards UniProt Show fit	CD164 molecule
chr5_+_115841878 Show fit	1.31	ENST00000316788.12	AP3S1 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 3 subunit sigma 1
chr10_-_126388455 Show fit	1.30	ENST00000368679.8 ENST00000368676.8 ENST00000448723.2	ADAM12 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 12
chr3_-_177196451 Show fit	1.29	ENST00000430069.5 ENST00000630796.2 ENST00000428970.5	TBL1XR1 Ensembl NCBI GeneCards UniProt Show fit	TBL1X receptor 1
chr18_-_49492305 Show fit	1.27	ENST00000615479.4 ENST00000583637.5 ENST00000618613.5 ENST00000615760.4 ENST00000578528.1 ENST00000578532.5 ENST00000580387.5 ENST00000579248.5 ENST00000580261.6 ENST00000581373.5 ENST00000618619.4 ENST00000617346.4 ENST00000583036.5 ENST00000332968.11	RPL17 Ensembl NCBI GeneCards UniProt Show fit RPL17-C18orf32 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L17 RPL17-C18orf32 readthrough
chr11_-_68271896 Show fit	1.26	ENST00000533310.5 ENST00000304271.11 ENST00000527280.1	C11orf24 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 24
chr6_+_116370938 Show fit	1.26	ENST00000644252.3 ENST00000646710.1 ENST00000359564.3	DSE Ensembl NCBI GeneCards UniProt Show fit	dermatan sulfate epimerase
chr11_+_9573633 Show fit	1.26	ENST00000450114.7	WEE1 Ensembl NCBI GeneCards UniProt Show fit	WEE1 G2 checkpoint kinase
chr5_+_127517611 Show fit	1.25	ENST00000296666.13 ENST00000442138.6 ENST00000512635.2	PRRC1 Ensembl NCBI GeneCards UniProt Show fit	proline rich coiled-coil 1
chr11_+_17276989 Show fit	1.25	ENST00000533926.5	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chr14_-_24195334 Show fit	1.24	ENST00000530563.1 ENST00000528895.5 ENST00000528669.5 ENST00000532632.1 ENST00000261789.9	TM9SF1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 1
chr9_-_35689913 Show fit	1.24	ENST00000329305.6 ENST00000645482.3 ENST00000647435.1 ENST00000378292.9	TPM2 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 2
chr4_+_8592750 Show fit	1.22	ENST00000315782.6 ENST00000360986.9	CPZ Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase Z
chr6_+_63211446 Show fit	1.22	ENST00000370659.1	FKBP1C Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase family member 1C
chr19_+_7637099 Show fit	1.21	ENST00000595950.5 ENST00000221283.10 ENST00000441779.6 ENST00000414284.6	STXBP2 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 2
chr5_+_120464236 Show fit	1.21	ENST00000407149.7 ENST00000379551.2	PRR16 Ensembl NCBI GeneCards UniProt Show fit	proline rich 16
chr17_+_38870050 Show fit	1.20	ENST00000318008.11 ENST00000435347.7	LASP1 Ensembl NCBI GeneCards UniProt Show fit	LIM and SH3 protein 1
chr2_-_69387130 Show fit	1.20	ENST00000674438.1	GFPT1 Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr5_-_172454487 Show fit	1.18	ENST00000311601.6	SH3PXD2B Ensembl NCBI GeneCards UniProt Show fit	SH3 and PX domains 2B
chr1_-_23799533 Show fit	1.17	ENST00000429356.5	GALE Ensembl NCBI GeneCards UniProt Show fit	UDP-galactose-4-epimerase
chr5_+_177303768 Show fit	1.17	ENST00000303204.9 ENST00000503216.5	PRELID1 Ensembl NCBI GeneCards UniProt Show fit	PRELI domain containing 1
chr14_-_24195570 Show fit	1.17	ENST00000530468.5 ENST00000528010.1 ENST00000396854.8 ENST00000524835.5 ENST00000525592.1	TM9SF1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 1
chr10_-_22003678 Show fit	1.16	ENST00000376980.8	DNAJC1 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C1
chr2_+_27032938 Show fit	1.16	ENST00000238788.14 ENST00000404032.7	TMEM214 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 214
chr22_-_31107517 Show fit	1.14	ENST00000400299.6 ENST00000611680.1	SELENOM Ensembl NCBI GeneCards UniProt Show fit	selenoprotein M
chr1_-_86914319 Show fit	1.13	ENST00000611507.4 ENST00000616787.4	SELENOF Ensembl NCBI GeneCards UniProt Show fit	selenoprotein F
chr1_+_6785518 Show fit	1.11	ENST00000467404.6	CAMTA1 Ensembl NCBI GeneCards UniProt Show fit	calmodulin binding transcription activator 1
chr11_-_66289125 Show fit	1.09	ENST00000471387.6 ENST00000376901.9 ENST00000359461.10	YIF1A Ensembl NCBI GeneCards UniProt Show fit	Yip1 interacting factor homolog A, membrane trafficking protein
chr1_-_86914102 Show fit	1.06	ENST00000331835.10 ENST00000401030.4 ENST00000370554.5	SELENOF Ensembl NCBI GeneCards UniProt Show fit	selenoprotein F
chr21_-_17612842 Show fit	1.05	ENST00000339775.10 ENST00000348354.7	BTG3 Ensembl NCBI GeneCards UniProt Show fit	BTG anti-proliferation factor 3
chr9_+_99222258 Show fit	1.00	ENST00000223641.5	SEC61B Ensembl NCBI GeneCards UniProt Show fit	SEC61 translocon subunit beta
chr1_+_26432299 Show fit	0.99	ENST00000427245.6 ENST00000236342.12 ENST00000525682.6 ENST00000526219.5 ENST00000374185.7 ENST00000360009.6 ENST00000533087.5 ENST00000531312.5 ENST00000525165.5 ENST00000525326.5 ENST00000525546.5 ENST00000436153.6 ENST00000530781.5	DHDDS Ensembl NCBI GeneCards UniProt Show fit	dehydrodolichyl diphosphate synthase subunit
chr17_+_47971105 Show fit	0.99	ENST00000338399.9 ENST00000578018.5 ENST00000579175.5	CDK5RAP3 Ensembl NCBI GeneCards UniProt Show fit	CDK5 regulatory subunit associated protein 3
chr22_-_30326923 Show fit	0.98	ENST00000215790.12	TBC1D10A Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 10A
chr10_+_102918344 Show fit	0.97	ENST00000433628.2	CNNM2 Ensembl NCBI GeneCards UniProt Show fit	cyclin and CBS domain divalent metal cation transport mediator 2
chr10_-_70170466 Show fit	0.96	ENST00000373239.2 ENST00000373241.9 ENST00000373242.6	SAR1A Ensembl NCBI GeneCards UniProt Show fit	secretion associated Ras related GTPase 1A
chr9_+_111631354 Show fit	0.95	ENST00000374294.3	DNAJC25-GNG10 Ensembl NCBI GeneCards UniProt Show fit	DNAJC25-GNG10 readthrough
chr11_-_66289007 Show fit	0.95	ENST00000431556.6 ENST00000528575.1	YIF1A Ensembl NCBI GeneCards UniProt Show fit	Yip1 interacting factor homolog A, membrane trafficking protein
chr7_+_128739292 Show fit	0.94	ENST00000535011.6 ENST00000542996.6 ENST00000249364.9 ENST00000449187.6	CALU Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr10_+_18659382 Show fit	0.92	ENST00000377275.4	ARL5B Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 5B
chr3_+_105367212 Show fit	0.91	ENST00000472644.6	ALCAM Ensembl NCBI GeneCards UniProt Show fit	activated leukocyte cell adhesion molecule
chr2_+_84905644 Show fit	0.91	ENST00000233143.6	TMSB10 Ensembl NCBI GeneCards UniProt Show fit	thymosin beta 10
chr11_+_47408582 Show fit	0.88	ENST00000531974.5 ENST00000362021.9 ENST00000531419.5 ENST00000531865.5 ENST00000354884.8	SLC39A13 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 13
chr11_-_119057185 Show fit	0.85	ENST00000614668.4 ENST00000617285.5	HYOU1 Ensembl NCBI GeneCards UniProt Show fit	hypoxia up-regulated 1
chr3_-_105868964 Show fit	0.85	ENST00000394030.8	CBLB Ensembl NCBI GeneCards UniProt Show fit	Cbl proto-oncogene B
chr22_-_30326877 Show fit	0.85	ENST00000403477.7	TBC1D10A Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 10A
chr2_+_241315092 Show fit	0.84	ENST00000391973.6	SEPTIN2 Ensembl NCBI GeneCards UniProt Show fit	septin 2
chr17_+_47971136 Show fit	0.81	ENST00000583352.5	CDK5RAP3 Ensembl NCBI GeneCards UniProt Show fit	CDK5 regulatory subunit associated protein 3
chr14_-_23365149 Show fit	0.81	ENST00000216733.8	EFS Ensembl NCBI GeneCards UniProt Show fit	embryonal Fyn-associated substrate
chr12_-_55729660 Show fit	0.80	ENST00000546457.1 ENST00000549117.5	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr15_-_60397964 Show fit	0.80	ENST00000558998.5 ENST00000560165.5 ENST00000557986.5 ENST00000559467.5 ENST00000677968.1 ENST00000678450.1 ENST00000332680.8 ENST00000396024.7 ENST00000557906.6 ENST00000558558.6 ENST00000559113.6 ENST00000559780.6 ENST00000559956.6 ENST00000560468.6 ENST00000678870.1 ENST00000678061.1 ENST00000451270.7 ENST00000421017.6 ENST00000560466.5 ENST00000558132.5 ENST00000559370.5 ENST00000559725.5 ENST00000558985.6 ENST00000679109.1	ANXA2 Ensembl NCBI GeneCards UniProt Show fit	annexin A2
chr3_+_33114007 Show fit	0.79	ENST00000320954.11	CRTAP Ensembl NCBI GeneCards UniProt Show fit	cartilage associated protein
chr11_-_62646598 Show fit	0.77	ENST00000648273.1 ENST00000356638.8 ENST00000346178.8 ENST00000534779.5 ENST00000525994.1 ENST00000540933.5	GANAB Ensembl NCBI GeneCards UniProt Show fit	glucosidase II alpha subunit
chr19_-_10333512 Show fit	0.76	ENST00000617231.5 ENST00000611074.4 ENST00000615032.4	RAVER1 Ensembl NCBI GeneCards UniProt Show fit	ribonucleoprotein, PTB binding 1
chr8_-_123042244 Show fit	0.76	ENST00000259512.9 ENST00000419562.6	DERL1 Ensembl NCBI GeneCards UniProt Show fit	derlin 1
chr1_-_204494752 Show fit	0.76	ENST00000684373.1	PIK3C2B Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr11_-_119057218 Show fit	0.75	ENST00000652093.1	HYOU1 Ensembl NCBI GeneCards UniProt Show fit	hypoxia up-regulated 1
chr16_-_82011444 Show fit	0.74	ENST00000328945.7 ENST00000532128.5	SDR42E1 Ensembl NCBI GeneCards UniProt Show fit	short chain dehydrogenase/reductase family 42E, member 1
chr1_+_6785437 Show fit	0.73	ENST00000303635.12 ENST00000473578.5 ENST00000557126.5	CAMTA1 Ensembl NCBI GeneCards UniProt Show fit	calmodulin binding transcription activator 1
chr2_-_219543537 Show fit	0.69	ENST00000373891.2	CHPF Ensembl NCBI GeneCards UniProt Show fit	chondroitin polymerizing factor
chr18_-_36828771 Show fit	0.69	ENST00000589049.5 ENST00000587129.5 ENST00000590842.5	TPGS2 Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr5_+_154858218 Show fit	0.69	ENST00000523698.5 ENST00000517876.5 ENST00000520472.5	CNOT8 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 8
chr7_+_128739395 Show fit	0.69	ENST00000479257.5	CALU Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr15_+_79311137 Show fit	0.68	ENST00000424155.6 ENST00000536821.5	TMED3 Ensembl NCBI GeneCards UniProt Show fit	transmembrane p24 trafficking protein 3
chr11_+_17276795 Show fit	0.66	ENST00000530964.5	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chr2_-_219543793 Show fit	0.65	ENST00000243776.11	CHPF Ensembl NCBI GeneCards UniProt Show fit	chondroitin polymerizing factor
chr18_-_36829154 Show fit	0.64	ENST00000614939.4 ENST00000610723.4	TPGS2 Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr21_-_17612911 Show fit	0.64	ENST00000457956.1	BTG3 Ensembl NCBI GeneCards UniProt Show fit	BTG anti-proliferation factor 3
chr19_-_18919348 Show fit	0.63	ENST00000349893.8 ENST00000351079.8 ENST00000600932.5 ENST00000262812.9	COPE Ensembl NCBI GeneCards UniProt Show fit	COPI coat complex subunit epsilon
chr7_-_30026617 Show fit	0.63	ENST00000222803.10	FKBP14 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 14
chr2_+_241315338 Show fit	0.63	ENST00000428524.5 ENST00000445030.5 ENST00000407017.5	SEPTIN2 Ensembl NCBI GeneCards UniProt Show fit	septin 2
chr11_-_119057105 Show fit	0.62	ENST00000534233.5 ENST00000614711.4 ENST00000530467.5 ENST00000621959.4 ENST00000532519.6 ENST00000532421.5 ENST00000610597.1 ENST00000612687.4	HYOU1 Ensembl NCBI GeneCards UniProt Show fit	hypoxia up-regulated 1
chr7_+_100949525 Show fit	0.62	ENST00000379458.9 ENST00000483366.5	MUC3A Ensembl NCBI GeneCards UniProt Show fit	mucin 3A, cell surface associated
chr4_+_140524179 Show fit	0.61	ENST00000507667.1	ELMOD2 Ensembl NCBI GeneCards UniProt Show fit	ELMO domain containing 2
chr1_-_155173245 Show fit	0.60	ENST00000497317.5 ENST00000482246.5 ENST00000295682.6	KRTCAP2 Ensembl NCBI GeneCards UniProt Show fit	keratinocyte associated protein 2
chr2_-_88627365 Show fit	0.60	ENST00000303236.9	EIF2AK3 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 alpha kinase 3
chr18_-_36828939 Show fit	0.60	ENST00000593035.5 ENST00000383056.7 ENST00000588909.1 ENST00000590337.5 ENST00000334295.9	TPGS2 Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr2_-_157628727 Show fit	0.60	ENST00000335450.7 ENST00000348328.9	ACVR1C Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 1C
chr1_-_45522870 Show fit	0.59	ENST00000424390.2	PRDX1 Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 1
chr2_-_241315180 Show fit	0.58	ENST00000441124.5 ENST00000391976.6	HDLBP Ensembl NCBI GeneCards UniProt Show fit	high density lipoprotein binding protein
chr9_+_35732649 Show fit	0.57	ENST00000353704.3	CREB3 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 3
chr6_-_107958165 Show fit	0.56	ENST00000369002.9	SEC63 Ensembl NCBI GeneCards UniProt Show fit	SEC63 homolog, protein translocation regulator
chr8_-_123042122 Show fit	0.56	ENST00000405944.7	DERL1 Ensembl NCBI GeneCards UniProt Show fit	derlin 1
chr17_-_15563428 Show fit	0.56	ENST00000584811.5 ENST00000419890.3 ENST00000518321.6 ENST00000438826.7 ENST00000225576.7 ENST00000428082.6 ENST00000522212.6	TVP23C Ensembl NCBI GeneCards UniProt Show fit TVP23C-CDRT4 Ensembl NCBI GeneCards UniProt Show fit	trans-golgi network vesicle protein 23 homolog C TVP23C-CDRT4 readthrough
chr11_+_61828280 Show fit	0.55	ENST00000521849.5 ENST00000278840.9	FADS2 Ensembl NCBI GeneCards UniProt Show fit	fatty acid desaturase 2
chr3_+_133805789 Show fit	0.55	ENST00000678299.1	SRPRB Ensembl NCBI GeneCards UniProt Show fit	SRP receptor subunit beta
chr12_-_106247950 Show fit	0.55	ENST00000378026.5	CKAP4 Ensembl NCBI GeneCards UniProt Show fit	cytoskeleton associated protein 4
chrX_+_154398890 Show fit	0.54	ENST00000406022.6	RPL10 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L10
chr13_+_45464995 Show fit	0.54	ENST00000617493.1	COG3 Ensembl NCBI GeneCards UniProt Show fit	component of oligomeric golgi complex 3
chr19_-_10315987 Show fit	0.54	ENST00000393708.3 ENST00000494368.5	FDX2 Ensembl NCBI GeneCards UniProt Show fit	ferredoxin 2
chr16_+_726936 Show fit	0.53	ENST00000549114.5 ENST00000341413.8 ENST00000562187.1 ENST00000564537.5 ENST00000389703.8	HAGHL Ensembl NCBI GeneCards UniProt Show fit	hydroxyacylglutathione hydrolase like
chr7_-_64982021 Show fit	0.53	ENST00000610793.1 ENST00000620222.4	ZNF117 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 117
chr19_-_52095704 Show fit	0.52	ENST00000594440.6 ENST00000426391.6	ZNF841 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 841
chr12_+_6944065 Show fit	0.51	ENST00000540506.2	C12orf57 Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 57
chr12_-_27970047 Show fit	0.51	ENST00000395868.7	PTHLH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone like hormone
chr13_-_45341086 Show fit	0.51	ENST00000309246.9 ENST00000379060.8 ENST00000379055.5 ENST00000527226.2 ENST00000530705.6 ENST00000379056.5 ENST00000616577.4	TPT1 Ensembl NCBI GeneCards UniProt Show fit	tumor protein, translationally-controlled 1
chr12_+_6944009 Show fit	0.51	ENST00000229281.6	C12orf57 Ensembl NCBI GeneCards UniProt Show fit	chromosome 12 open reading frame 57
chr3_-_10321041 Show fit	0.49	ENST00000397109.7 ENST00000428626.5 ENST00000445064.1 ENST00000431352.1 ENST00000397117.5 ENST00000337354.8 ENST00000383801.6 ENST00000432213.1 ENST00000350697.8	SEC13 Ensembl NCBI GeneCards UniProt Show fit	SEC13 homolog, nuclear pore and COPII coat complex component
chr12_+_56468561 Show fit	0.47	ENST00000338146.7	SPRYD4 Ensembl NCBI GeneCards UniProt Show fit	SPRY domain containing 4
chr12_-_132828823 Show fit	0.44	ENST00000545875.4 ENST00000456883.6 ENST00000450791.7 ENST00000204726.8	GOLGA3 Ensembl NCBI GeneCards UniProt Show fit	golgin A3
chr15_-_74873310 Show fit	0.44	ENST00000562363.5 ENST00000564529.1 ENST00000268099.13	SCAMP2 Ensembl NCBI GeneCards UniProt Show fit	secretory carrier membrane protein 2
chr3_-_28348805 Show fit	0.43	ENST00000457172.5 ENST00000479665.6	AZI2 Ensembl NCBI GeneCards UniProt Show fit	5-azacytidine induced 2
chr12_-_108731505 Show fit	0.42	ENST00000261401.8 ENST00000552871.5	CORO1C Ensembl NCBI GeneCards UniProt Show fit	coronin 1C
chr11_-_119056850 Show fit	0.42	ENST00000530473.5	HYOU1 Ensembl NCBI GeneCards UniProt Show fit	hypoxia up-regulated 1
chr12_-_27970273 Show fit	0.42	ENST00000542963.1 ENST00000535992.5	PTHLH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone like hormone
chr11_-_93543382 Show fit	0.40	ENST00000298966.7	SMCO4 Ensembl NCBI GeneCards UniProt Show fit	single-pass membrane protein with coiled-coil domains 4
chr3_+_50246888 Show fit	0.40	ENST00000451956.1	GNAI2 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha i2
chr3_+_132660305 Show fit	0.39	ENST00000683741.1 ENST00000468022.5 ENST00000356232.10 ENST00000473651.5 ENST00000494238.6	UBA5 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like modifier activating enzyme 5
chr5_-_61162352 Show fit	0.39	ENST00000339020.8 ENST00000507416.1	SMIM15 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 15
chr16_-_30534954 Show fit	0.38	ENST00000568028.1	ZNF747 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 747
chr10_+_102918276 Show fit	0.38	ENST00000369878.9 ENST00000369875.3	CNNM2 Ensembl NCBI GeneCards UniProt Show fit	cyclin and CBS domain divalent metal cation transport mediator 2
chr18_-_49491586 Show fit	0.36	ENST00000584895.5 ENST00000580210.5 ENST00000579408.5	RPL17-C18orf32 Ensembl NCBI GeneCards UniProt Show fit RPL17 Ensembl NCBI GeneCards UniProt Show fit	RPL17-C18orf32 readthrough ribosomal protein L17
chr4_+_140524147 Show fit	0.36	ENST00000511887.6 ENST00000323570.8	ELMOD2 Ensembl NCBI GeneCards UniProt Show fit	ELMO domain containing 2
chr22_-_42857194 Show fit	0.36	ENST00000437119.6 ENST00000454099.5 ENST00000263245.10	ARFGAP3 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor GTPase activating protein 3
chr20_-_63568074 Show fit	0.36	ENST00000427522.6	HELZ2 Ensembl NCBI GeneCards UniProt Show fit	helicase with zinc finger 2
chr2_-_213152427 Show fit	0.35	ENST00000452786.2	IKZF2 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 2
chr16_+_727117 Show fit	0.35	ENST00000562141.5	HAGHL Ensembl NCBI GeneCards UniProt Show fit	hydroxyacylglutathione hydrolase like
chr1_-_21783189 Show fit	0.35	ENST00000400301.5 ENST00000532737.1	USP48 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 48
chr19_+_18919688 Show fit	0.35	ENST00000247003.9	DDX49 Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 49
chr19_-_10315737 Show fit	0.34	ENST00000492239.5	FDX2 Ensembl NCBI GeneCards UniProt Show fit	ferredoxin 2
chr1_-_21783134 Show fit	0.34	ENST00000308271.14	USP48 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 48
chr4_+_128061500 Show fit	0.34	ENST00000649983.1 ENST00000648358.1 ENST00000650359.1	LARP1B Ensembl NCBI GeneCards UniProt Show fit	La ribonucleoprotein 1B
chr1_+_109984756 Show fit	0.33	ENST00000393614.8 ENST00000369799.10	AHCYL1 Ensembl NCBI GeneCards UniProt Show fit	adenosylhomocysteinase like 1
chr19_-_8005590 Show fit	0.33	ENST00000407627.7 ENST00000593807.1	ELAVL1 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 1
chr6_-_89352706 Show fit	0.31	ENST00000435041.3	UBE2J1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 J1
chr5_-_177303675 Show fit	0.31	ENST00000393611.6 ENST00000303270.6 ENST00000303251.11	RAB24 Ensembl NCBI GeneCards UniProt Show fit	RAB24, member RAS oncogene family
chrX_+_1591590 Show fit	0.30	ENST00000313871.9 ENST00000381261.8	AKAP17A Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 17A
chr5_+_154858482 Show fit	0.29	ENST00000519211.5 ENST00000522458.5 ENST00000519903.5 ENST00000521450.5 ENST00000403027.6	CNOT8 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 8
chr5_-_177303732 Show fit	0.29	ENST00000504395.1	RAB24 Ensembl NCBI GeneCards UniProt Show fit	RAB24, member RAS oncogene family
chr16_+_727246 Show fit	0.29	ENST00000561546.5 ENST00000564545.1 ENST00000567414.5 ENST00000568141.5	HAGHL Ensembl NCBI GeneCards UniProt Show fit	hydroxyacylglutathione hydrolase like

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.0	GO:0072272	proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
1.5	4.5	GO:0000103	sulfate assimilation(GO:0000103)
1.2	4.6	GO:0060435	bronchiole development(GO:0060435)
1.0	3.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
1.0	16.4	GO:0043589	skin morphogenesis(GO:0043589)
0.8	2.4	GO:1901874	negative regulation of post-translational protein modification(GO:1901874)
0.8	3.2	GO:0052227	multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.8	2.4	GO:0071529	cementum mineralization(GO:0071529)
0.6	7.1	GO:0006621	protein retention in ER lumen(GO:0006621)
0.5	1.6	GO:0031204	posttranslational protein targeting to membrane, translocation(GO:0031204)
0.5	1.0	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.4	1.7	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
0.4	5.5	GO:0048251	elastic fiber assembly(GO:0048251)
0.4	2.0	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.4	3.1	GO:0036483	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.4	5.8	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.3	6.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.3	2.0	GO:0019348	dolichol metabolic process(GO:0019348)
0.3	1.5	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3	2.1	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.3	1.7	GO:0006177	GMP biosynthetic process(GO:0006177)
0.3	4.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.2	2.4	GO:0071569	protein ufmylation(GO:0071569)
0.2	1.3	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2	1.8	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.2	9.1	GO:0006882	cellular zinc ion homeostasis(GO:0006882)
0.2	0.6	GO:1901383	negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.2	2.9	GO:0019388	galactose catabolic process(GO:0019388)
0.2	0.6	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1	1.2	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.1	1.1	GO:0035934	corticosterone secretion(GO:0035934)
0.1	1.6	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1	1.2	GO:0036343	psychomotor behavior(GO:0036343)
0.1	2.3	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.1	1.2	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	1.6	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	1.6	GO:0060613	fat pad development(GO:0060613)
0.1	0.6	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	1.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.2	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	2.2	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.1	0.8	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	2.6	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.1	2.6	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	6.0	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.1	GO:1903006	flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.0	3.4	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	5.7	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.0	0.3	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	3.0	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.3	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	1.3	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	2.8	GO:0010165	response to X-ray(GO:0010165)
0.0	0.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.9	GO:1902284	axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0	5.3	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.2	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.4	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0	1.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	1.9	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.3	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.6	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.3	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	1.8	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.9	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	7.7	GO:0001649	osteoblast differentiation(GO:0001649)
0.0	2.4	GO:0043462	regulation of ATPase activity(GO:0043462)
0.0	1.0	GO:0033006	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0	0.4	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.0	0.3	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
0.0	0.6	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	1.0	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	1.8	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	1.9	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.1	GO:0002270	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0	0.4	GO:0036109	alpha-linolenic acid metabolic process(GO:0036109)
0.0	0.6	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.0	1.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	1.6	GO:0019730	antimicrobial humoral response(GO:0019730)
0.0	0.5	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	2.8	GO:1903169	regulation of calcium ion transmembrane transport(GO:1903169)
0.0	0.3	GO:0044116	growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0	0.5	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.8	14.5	GO:0005584	collagen type I trimer(GO:0005584)
0.8	5.8	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.6	3.2	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.6	2.3	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3	5.7	GO:0030127	COPII vesicle coat(GO:0030127)
0.3	1.3	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.2	2.4	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.2	3.7	GO:0030126	COPI vesicle coat(GO:0030126)
0.2	3.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	3.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	2.4	GO:0017119	Golgi transport complex(GO:0017119)
0.1	1.2	GO:0044194	cytolytic granule(GO:0044194)
0.1	2.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	1.6	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	3.1	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	0.6	GO:0048179	activin receptor complex(GO:0048179)
0.1	1.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	0.5	GO:0045298	tubulin complex(GO:0045298)
0.1	0.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.6	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.3	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	1.0	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	2.4	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.8	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	9.5	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	7.6	GO:0005581	collagen trimer(GO:0005581)
0.0	9.9	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	16.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.0	1.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.9	GO:0042101	T cell receptor complex(GO:0042101)
0.0	5.9	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.4	GO:0016600	flotillin complex(GO:0016600)
0.0	2.6	GO:0005901	caveola(GO:0005901)
0.0	2.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.2	GO:0002102	podosome(GO:0002102)
0.0	1.5	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	1.4	GO:0031201	SNARE complex(GO:0031201)
0.0	1.3	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	1.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	19.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	1.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.2	GO:0097433	dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.5	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.7	14.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.7	2.9	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.7	7.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.6	2.6	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.6	3.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.5	5.5	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.4	1.6	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.4	2.0	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.4	3.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.3	2.4	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.3	1.7	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.3	1.0	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.3	1.3	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3	1.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2	10.8	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	1.6	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.2	0.6	GO:0038100	nodal binding(GO:0038100)
0.2	1.2	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.1	6.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	3.0	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	1.2	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	1.8	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	1.6	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	1.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.6	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.1	4.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	0.3	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.1	1.8	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	3.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	1.9	GO:0070513	death domain binding(GO:0070513)
0.1	0.4	GO:0016213	linoleoyl-CoA desaturase activity(GO:0016213)
0.1	0.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1	1.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0070012	oligopeptidase activity(GO:0070012)
0.1	0.6	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.6	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.8	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.1	0.8	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.3	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	1.8	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	1.5	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.3	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	1.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	1.5	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	2.1	GO:0005109	frizzled binding(GO:0005109)
0.0	1.0	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	2.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	1.6	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.9	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	4.3	GO:0051087	chaperone binding(GO:0051087)
0.0	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.0	5.6	GO:0003823	antigen binding(GO:0003823)
0.0	0.6	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.9	GO:0003785	actin monomer binding(GO:0003785)
0.0	4.7	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.3	GO:0046625	sphingolipid binding(GO:0046625)
0.0	1.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	1.9	GO:0008565	protein transporter activity(GO:0008565)
0.0	1.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.8	GO:0000149	SNARE binding(GO:0000149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	14.5	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	1.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	10.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	2.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.6	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	4.4	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	4.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.6	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	14.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	9.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	4.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	4.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	12.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	3.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	1.0	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	3.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	3.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	10.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	1.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	2.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	1.3	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	1.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	2.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	2.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.9	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	1.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane

Results for XBP1

Z-value: 1.67

Motif logo

Transcription factors associated with XBP1

Activity-expression correlation:

Activity profile of XBP1 motif

Sorted Z-values of XBP1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: