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Illumina Body Map 2 (GSE30611)

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Results for ZBTB18

Z-value: 2.14

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Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ENSG00000179456.10 zinc finger and BTB domain containing 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB18hg38_v1_chr1_+_244051275_244051291-0.522.2e-03Click!

Activity profile of ZBTB18 motif

Sorted Z-values of ZBTB18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_168729187 17.00 ENST00000367817.4
dermatopontin
chr2_+_188974364 13.90 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr19_+_11538767 13.63 ENST00000592923.5
ENST00000535659.6
calponin 1
chr19_+_11538844 13.30 ENST00000252456.7
calponin 1
chr1_+_53062052 11.65 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
podocan
chr1_-_16018005 9.83 ENST00000406363.2
ENST00000411503.5
ENST00000311890.14
ENST00000487046.1
heat shock protein family B (small) member 7
chr15_+_49423233 9.52 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr17_+_49575828 9.23 ENST00000328741.6
neurexophilin 3
chr11_-_69013233 9.08 ENST00000309099.7
ENST00000320913.6
MAS related GPR family member F
chr11_-_69013356 8.44 ENST00000441623.1
MAS related GPR family member F
chrX_+_100644183 8.11 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr17_+_79024142 8.01 ENST00000579760.6
ENST00000339142.6
C1q and TNF related 1
chr14_+_94110728 7.60 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
interferon alpha inducible protein 27
chr1_-_16980607 7.46 ENST00000375535.4
microfibril associated protein 2
chr13_+_113122791 7.15 ENST00000375559.8
ENST00000409306.5
ENST00000375551.7
coagulation factor X
chr12_-_104050112 7.10 ENST00000547583.1
ENST00000546851.1
ENST00000360814.9
glycosyltransferase 8 domain containing 2
chr11_-_123195208 6.70 ENST00000448775.4
CXADR like membrane protein
chr17_+_79024243 6.40 ENST00000311661.4
C1q and TNF related 1
chr3_+_100492548 6.39 ENST00000323523.8
ENST00000403410.5
ENST00000449609.1
transmembrane protein 45A
chr2_-_1744442 6.38 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr4_+_15374541 6.06 ENST00000382383.7
ENST00000429690.5
C1q and TNF related 7
chr4_-_151227881 6.04 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr14_-_38256074 6.03 ENST00000342213.3
C-type lectin domain containing 14A
chrX_+_43656289 6.02 ENST00000338702.4
monoamine oxidase A
chr2_-_162243375 5.98 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr17_+_62627628 5.78 ENST00000303375.10
mannose receptor C type 2
chr11_+_76783349 5.69 ENST00000333090.5
tsukushi, small leucine rich proteoglycan
chr17_-_15265230 5.67 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
peripheral myelin protein 22
chr1_-_16017825 5.60 ENST00000463576.5
heat shock protein family B (small) member 7
chr17_+_49576091 5.47 ENST00000513748.1
neurexophilin 3
chr8_-_48921419 5.37 ENST00000020945.4
snail family transcriptional repressor 2
chr19_-_35510384 5.30 ENST00000602679.5
ENST00000492341.6
ENST00000472252.6
ENST00000602781.5
ENST00000402589.6
ENST00000458071.5
ENST00000436012.5
ENST00000443640.5
ENST00000450261.1
ENST00000467637.5
ENST00000480502.5
ENST00000474928.5
ENST00000414866.6
ENST00000392206.6
ENST00000488892.5
dermokine
chr2_-_162242998 5.03 ENST00000627638.2
ENST00000447386.5
fibroblast activation protein alpha
chr4_+_74445126 5.03 ENST00000395748.8
amphiregulin
chr7_+_101127095 4.93 ENST00000223095.5
serpin family E member 1
chr2_-_65432591 4.91 ENST00000356388.9
sprouty related EVH1 domain containing 2
chr1_-_156677400 4.64 ENST00000368223.4
nestin
chr9_+_70043840 4.62 ENST00000377182.5
MAM domain containing 2
chr17_-_69141878 4.57 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr1_+_186296267 4.31 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
proteoglycan 4
chrX_-_155334580 4.23 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr4_+_74445302 4.19 ENST00000502307.1
amphiregulin
chr8_-_17697654 4.11 ENST00000297488.10
microtubule associated scaffold protein 1
chrX_-_102516714 4.08 ENST00000289373.5
thymosin beta 15A
chr17_-_43022350 3.96 ENST00000587173.5
ENST00000355653.8
vesicle amine transport 1
chr11_-_57322197 3.91 ENST00000532437.1
tankyrase 1 binding protein 1
chr20_+_3732675 3.90 ENST00000254963.7
ENST00000399701.1
heat shock protein family A (Hsp70) member 12B
chr11_-_101583985 3.80 ENST00000344327.8
transient receptor potential cation channel subfamily C member 6
chr20_+_58150896 3.77 ENST00000371168.4
chromosome 20 open reading frame 85
chr17_-_63972918 3.73 ENST00000435607.3
sodium voltage-gated channel alpha subunit 4
chr1_+_19640520 3.63 ENST00000428975.5
NBL1, DAN family BMP antagonist
chr19_+_40613416 3.60 ENST00000599724.5
ENST00000597071.5
latent transforming growth factor beta binding protein 4
chr2_-_65432628 3.43 ENST00000440972.1
sprouty related EVH1 domain containing 2
chr8_-_48921735 3.43 ENST00000396822.6
snail family transcriptional repressor 2
chr7_-_120857124 3.38 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr11_+_32091065 3.37 ENST00000054950.4
reticulocalbin 1
chr9_-_13165442 3.36 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr6_+_41637005 3.20 ENST00000419164.6
ENST00000373051.6
MyoD family inhibitor
chr3_-_146222426 3.16 ENST00000481701.5
phospholipid scramblase 4
chr3_+_30606574 2.96 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chr17_+_34285734 2.95 ENST00000305869.4
C-C motif chemokine ligand 11
chr8_+_24384455 2.91 ENST00000522298.1
ADAM like decysin 1
chr12_+_52079700 2.89 ENST00000546390.2
small integral membrane protein 41
chr16_-_49664225 2.87 ENST00000535559.5
zinc finger protein 423
chr19_-_10231293 2.86 ENST00000646641.1
sphingosine-1-phosphate receptor 2
chr9_+_94726657 2.82 ENST00000375315.8
ENST00000277198.6
ENST00000297979.9
aminopeptidase O (putative)
chr8_+_24384275 2.77 ENST00000256412.8
ADAM like decysin 1
chr17_+_38428456 2.76 ENST00000622683.5
ENST00000620417.4
Rho GTPase activating protein 23
chr12_+_2052977 2.70 ENST00000399634.6
ENST00000406454.8
ENST00000327702.12
ENST00000347598.9
ENST00000399603.6
ENST00000399641.6
ENST00000399655.6
ENST00000335762.10
ENST00000682835.1
calcium voltage-gated channel subunit alpha1 C
chr12_+_1629197 2.69 ENST00000397196.7
Wnt family member 5B
chr1_+_204073104 2.68 ENST00000367204.6
SRY-box transcription factor 13
chr17_+_9021501 2.66 ENST00000173229.7
netrin 1
chr2_+_33134620 2.64 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr17_+_34255274 2.63 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2
chr3_-_146222337 2.61 ENST00000498625.1
phospholipid scramblase 4
chr12_-_55727828 2.58 ENST00000546939.5
CD63 molecule
chr9_+_84668485 2.58 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
neurotrophic receptor tyrosine kinase 2
chr10_-_93482194 2.50 ENST00000358334.9
ENST00000371488.3
myoferlin
chr17_-_78360066 2.45 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chr1_+_77888645 2.43 ENST00000440324.5
nexilin F-actin binding protein
chr11_-_57322300 2.36 ENST00000527207.1
tankyrase 1 binding protein 1
chr1_-_207032749 2.34 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr13_-_33205997 2.34 ENST00000399365.7
StAR related lipid transfer domain containing 13
chr12_-_102481744 2.32 ENST00000644491.1
insulin like growth factor 1
chr1_+_77888612 2.32 ENST00000334785.12
nexilin F-actin binding protein
chr8_-_13276737 2.25 ENST00000503161.6
DLC1 Rho GTPase activating protein
chr12_-_55727796 2.23 ENST00000550776.5
CD63 molecule
chr4_-_110641920 2.22 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr18_+_6834473 2.19 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
Rho GTPase activating protein 28
chr12_-_16609869 2.17 ENST00000534946.5
LIM domain only 3
chr1_+_77888490 2.14 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr2_+_33134579 2.12 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr7_-_135748785 2.04 ENST00000338588.8
family with sequence similarity 180 member A
chr12_-_55728640 1.97 ENST00000551173.5
ENST00000420846.7
CD63 molecule
chr2_-_89117844 1.97 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr12_+_25973748 1.95 ENST00000542865.5
Ras association domain family member 8
chr1_+_37556913 1.84 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr18_+_3448456 1.82 ENST00000549780.5
TGFB induced factor homeobox 1
chr19_-_35510506 1.66 ENST00000461300.5
dermokine
chr2_-_88966767 1.58 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr1_-_153545793 1.52 ENST00000354332.8
ENST00000368716.9
S100 calcium binding protein A4
chr6_+_112236806 1.47 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chr12_-_55728339 1.44 ENST00000552754.5
CD63 molecule
chr10_-_93482287 1.38 ENST00000371489.5
myoferlin
chr6_+_41636882 1.34 ENST00000432027.5
MyoD family inhibitor
chr12_+_43836043 1.33 ENST00000266534.8
ENST00000551577.5
transmembrane protein 117
chr6_-_30556088 1.32 ENST00000433809.1
G protein nucleolar 1 (putative)
chr12_-_53727476 1.25 ENST00000549784.5
ENST00000262059.8
calcium binding and coiled-coil domain 1
chr6_-_162727748 1.23 ENST00000366892.5
ENST00000366898.6
ENST00000366897.5
ENST00000366896.5
ENST00000674250.1
parkin RBR E3 ubiquitin protein ligase
chrX_-_111270474 1.22 ENST00000324068.2
calpain 6
chr6_-_30556477 1.22 ENST00000376621.8
G protein nucleolar 1 (putative)
chrX_+_150361559 1.19 ENST00000262858.8
mastermind like domain containing 1
chr15_+_56918612 1.16 ENST00000438423.6
ENST00000267811.9
ENST00000333725.10
ENST00000559609.5
transcription factor 12
chr3_-_111595339 1.14 ENST00000317012.5
zinc finger BED-type containing 2
chr1_-_112618204 1.09 ENST00000369664.1
suppression of tumorigenicity 7 like
chr16_-_29862890 1.03 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr16_-_29863117 1.00 ENST00000566113.5
ENST00000569956.5
ENST00000570016.5
ENST00000219789.11
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr3_-_105869387 0.99 ENST00000438603.6
ENST00000443752.2
Cbl proto-oncogene B
chr9_+_128920966 0.90 ENST00000428610.5
ENST00000372592.8
phytanoyl-CoA dioxygenase domain containing 1
chr19_+_49581304 0.88 ENST00000246794.10
proline rich and Gla domain 2
chr17_-_19748285 0.85 ENST00000570414.1
ENST00000225740.11
aldehyde dehydrogenase 3 family member A1
chr11_-_1585283 0.83 ENST00000382171.2
keratin associated protein 5-1
chr7_-_135748712 0.82 ENST00000415751.1
family with sequence similarity 180 member A
chr17_-_19748341 0.81 ENST00000395555.7
aldehyde dehydrogenase 3 family member A1
chr2_-_85602351 0.80 ENST00000409668.1
transmembrane protein 150A
chr2_-_85602681 0.80 ENST00000334462.10
ENST00000306353.7
transmembrane protein 150A
chr1_+_37481656 0.72 ENST00000471012.1
zinc finger CCCH-type containing 12A
chr17_+_34270213 0.71 ENST00000378569.2
ENST00000394627.5
ENST00000394630.3
C-C motif chemokine ligand 7
chr19_+_42269219 0.65 ENST00000681038.1
capicua transcriptional repressor
chr7_+_97732046 0.64 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chr10_-_22003678 0.62 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr11_+_60056653 0.62 ENST00000278865.8
membrane spanning 4-domains A3
chr17_-_19748355 0.59 ENST00000494157.6
aldehyde dehydrogenase 3 family member A1
chr2_-_88992903 0.59 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr2_+_33134406 0.59 ENST00000432635.1
latent transforming growth factor beta binding protein 1
chr2_-_229232039 0.59 ENST00000354069.6
phosphotyrosine interaction domain containing 1
chr19_+_9093179 0.59 ENST00000429566.3
olfactory receptor family 1 subfamily M member 1
chr11_+_15114912 0.54 ENST00000379556.8
INSC spindle orientation adaptor protein
chr2_-_74465162 0.50 ENST00000649854.1
ENST00000650523.1
ENST00000649601.1
ENST00000448666.7
ENST00000409065.5
ENST00000414701.1
ENST00000452063.7
ENST00000649075.1
ENST00000648810.1
ENST00000462443.2
mannosyl-oligosaccharide glucosidase
chr14_+_67240713 0.49 ENST00000677382.1
membrane palmitoylated protein 5
chr19_+_39412650 0.48 ENST00000425673.6
pleckstrin homology and RhoGEF domain containing G2
chr2_+_201129318 0.46 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr11_+_5580877 0.46 ENST00000345043.2
olfactory receptor family 52 subfamily B member 6
chr19_+_53632056 0.45 ENST00000376650.1
divergent-paired related homeobox
chr9_+_113501359 0.39 ENST00000343817.9
ENST00000394646.7
regulator of G protein signaling 3
chr14_-_23057530 0.37 ENST00000397359.7
ENST00000610348.1
cadherin 24
chr11_+_60056587 0.35 ENST00000395032.6
ENST00000358152.6
membrane spanning 4-domains A3
chr10_+_88802730 0.32 ENST00000404743.9
lipase family member M
chr7_-_47539240 0.31 ENST00000450444.5
tensin 3
chr15_-_31161157 0.27 ENST00000542188.5
transient receptor potential cation channel subfamily M member 1
chr12_+_53452817 0.27 ENST00000550192.5
ENST00000551104.5
poly(rC) binding protein 2
chr16_-_87334273 0.26 ENST00000568879.1
novel protein
chr20_+_58907981 0.25 ENST00000656419.1
GNAS complex locus
chr16_-_67150951 0.24 ENST00000449549.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr1_+_42153399 0.23 ENST00000372581.2
guanylate cyclase activator 2B
chr8_+_38805442 0.21 ENST00000524193.1
transforming acidic coiled-coil containing protein 1
chr11_+_72189659 0.20 ENST00000393681.6
folate receptor alpha
chr14_-_20036038 0.20 ENST00000641664.1
ENST00000641904.1
olfactory receptor family 4 subfamily K member 13
chr10_+_70052582 0.18 ENST00000676699.1
macroH2A.2 histone
chr9_+_124261427 0.17 ENST00000373596.5
ENST00000425237.5
NIMA related kinase 6
chr13_-_60013178 0.16 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr15_-_31160954 0.16 ENST00000558445.5
ENST00000559177.5
transient receptor potential cation channel subfamily M member 1
chr7_-_157010615 0.15 ENST00000252971.11
motor neuron and pancreas homeobox 1
chr16_+_28903359 0.14 ENST00000564112.1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr5_-_151924846 0.13 ENST00000274576.9
glycine receptor alpha 1
chr19_-_15808126 0.11 ENST00000334920.3
olfactory receptor family 10 subfamily H member 1
chr12_+_27466810 0.11 ENST00000298876.8
ENST00000416383.5
single-pass membrane protein with coiled-coil domains 2
chr14_-_23057506 0.10 ENST00000487137.7
cadherin 24
chr9_-_104605627 0.09 ENST00000542196.2
olfactory receptor family 13 subfamily C member 2
chrX_+_48383516 0.09 ENST00000620320.4
ENST00000595689.3
SSX family member 4
chr2_+_29118195 0.07 ENST00000449202.5
CAP-Gly domain containing linker protein family member 4
chr3_-_37174578 0.03 ENST00000336686.9
LRR binding FLII interacting protein 2
chr10_+_5196831 0.03 ENST00000263126.3
aldo-keto reductase family 1 member C4
chr4_-_104494882 0.03 ENST00000394767.3
CXXC finger protein 4
chr3_+_49007062 0.03 ENST00000395474.7
ENST00000610967.4
ENST00000429900.6
WD repeat domain 6
chr19_+_50432885 0.02 ENST00000357701.6
myosin binding protein C2
chr8_+_39107529 0.02 ENST00000399831.7
ENST00000437682.6
ENST00000519315.5
ADAM metallopeptidase domain 32
chr3_+_159852933 0.00 ENST00000482804.1
schwannomin interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
2.9 8.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.1 14.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.8 11.0 GO:0097325 melanocyte proliferation(GO:0097325)
1.6 4.9 GO:0001300 chronological cell aging(GO:0001300)
1.5 13.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.4 7.0 GO:1903575 cornified envelope assembly(GO:1903575)
1.3 9.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
1.1 5.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.1 26.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
1.1 7.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
1.0 3.0 GO:0060434 bronchus morphogenesis(GO:0060434)
0.9 2.6 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.9 2.6 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.7 2.2 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.7 2.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 3.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.7 7.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.7 5.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.6 2.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 3.0 GO:0035962 response to interleukin-13(GO:0035962)
0.5 8.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.5 2.3 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4 4.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.4 2.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.4 2.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.4 6.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.3 8.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 6.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 12.9 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.3 2.7 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.3 17.0 GO:0030199 collagen fibril organization(GO:0030199)
0.3 4.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 0.7 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.2 6.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2 5.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 4.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2 3.9 GO:0001778 plasma membrane repair(GO:0001778)
0.2 5.7 GO:0032060 bleb assembly(GO:0032060)
0.2 6.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.5 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.2 2.7 GO:0070307 lens fiber cell development(GO:0070307)
0.2 6.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.6 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 2.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 4.6 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.1 0.6 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.7 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
0.1 14.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 7.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 2.8 GO:0002003 angiotensin maturation(GO:0002003)
0.1 3.5 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.4 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 7.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.2 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 2.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 3.4 GO:0010842 retina layer formation(GO:0010842)
0.1 5.8 GO:0030574 collagen catabolic process(GO:0030574)
0.1 7.1 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.1 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 14.6 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 5.9 GO:0048565 digestive tract development(GO:0048565)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 2.3 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 2.0 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.0 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 11.0 GO:0071438 invadopodium membrane(GO:0071438)
0.5 8.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 12.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 3.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 2.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 9.4 GO:0043218 compact myelin(GO:0043218)
0.2 7.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 15.9 GO:0016235 aggresome(GO:0016235)
0.2 3.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 6.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 19.0 GO:0005581 collagen trimer(GO:0005581)
0.1 9.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0035841 new growing cell tip(GO:0035841)
0.1 46.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 6.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 7.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 15.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 39.7 GO:0005925 focal adhesion(GO:0005925)
0.0 8.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 3.9 GO:0005901 caveola(GO:0005901)
0.0 4.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 10.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.8 GO:0030286 dynein complex(GO:0030286)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 10.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 8.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.6 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.2 6.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.0 5.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.0 3.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.9 5.3 GO:0050436 microfibril binding(GO:0050436)
0.9 2.6 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.7 13.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.7 2.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.6 3.0 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.6 6.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 6.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 15.4 GO:0031005 filamin binding(GO:0031005)
0.3 3.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 11.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 3.6 GO:0016015 morphogen activity(GO:0016015)
0.3 9.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 2.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 5.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 4.6 GO:0019215 intermediate filament binding(GO:0019215)
0.2 2.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 31.8 GO:0005518 collagen binding(GO:0005518)
0.2 7.6 GO:0005521 lamin binding(GO:0005521)
0.2 2.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 2.9 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 9.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 3.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 4.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 2.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 26.9 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 6.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 1.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 8.1 GO:0019838 growth factor binding(GO:0019838)
0.0 2.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 4.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 5.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 10.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 6.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 4.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.5 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 2.2 GO:0003823 antigen binding(GO:0003823)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 6.3 PID EPO PATHWAY EPO signaling pathway
0.2 9.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 13.9 NABA COLLAGENS Genes encoding collagen proteins
0.2 53.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 7.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 14.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 5.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 4.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 26.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 9.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.9 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 3.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 2.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 2.6 PID SHP2 PATHWAY SHP2 signaling
0.0 3.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 9.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 5.7 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 7.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 9.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.2 6.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 4.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 13.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 6.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 6.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 6.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 7.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 6.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 8.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 7.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.1 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis