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Illumina Body Map 2 (GSE30611)

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Results for ZBTB3

Z-value: 0.71

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Transcription factors associated with ZBTB3

Gene Symbol Gene ID Gene Info
ZBTB3
ENSG00000185670.9 zinc finger and BTB domain containing 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB3hg38_v1_chr11_-_62754141_627541840.067.6e-01Click!

Activity profile of ZBTB3 motif

Sorted Z-values of ZBTB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_39281261 3.58 ENST00000541347.5
ENST00000412814.1
CX3CR1
C-X3-C motif chemokine receptor 1
chr6_-_41154326 2.77 ENST00000426005.6
ENST00000437044.2
ENST00000373127.8
TREML1
triggering receptor expressed on myeloid cells like 1
chr6_+_122779707 2.66 ENST00000368444.8
ENST00000356535.4
FABP7
fatty acid binding protein 7
chr12_-_62192762 2.36 ENST00000416284.8
TAFA2
TAFA chemokine like family member 2
chr5_-_150290093 2.30 ENST00000672479.1
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
chr21_-_46605073 2.24 ENST00000291700.9
ENST00000367071.4
S100B
S100 calcium binding protein B
chr14_+_22070548 1.51 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr4_+_158201575 1.49 ENST00000505049.5
ENST00000505189.5
ENST00000511038.5
TMEM144
transmembrane protein 144
chr2_-_151971750 1.45 ENST00000636598.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr1_-_110606009 1.44 ENST00000640774.2
ENST00000638616.2
KCNA2
potassium voltage-gated channel subfamily A member 2
chr1_-_169586539 1.43 ENST00000367796.3
F5
coagulation factor V
chr12_+_48183602 1.35 ENST00000316554.5
CCDC184
coiled-coil domain containing 184
chr1_-_110606347 1.31 ENST00000316361.10
KCNA2
potassium voltage-gated channel subfamily A member 2
chr5_+_112738331 1.26 ENST00000512211.6
APC
APC regulator of WNT signaling pathway
chrX_+_71144818 1.24 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
NLGN3
neuroligin 3
chr1_-_169586471 1.15 ENST00000367797.9
F5
coagulation factor V
chr3_-_195442853 1.15 ENST00000635383.1
ENST00000439666.1
ENST00000618471.4
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr18_+_34493289 1.14 ENST00000682923.1
ENST00000596745.5
ENST00000283365.14
ENST00000315456.10
ENST00000598774.6
ENST00000684266.1
ENST00000683092.1
ENST00000683379.1
ENST00000684359.1
DTNA
dystrobrevin alpha
chr2_-_2326161 1.08 ENST00000649810.1
ENST00000648318.1
MYT1L
myelin transcription factor 1 like
chr2_-_2326210 1.07 ENST00000647755.1
MYT1L
myelin transcription factor 1 like
chr5_+_139273752 1.06 ENST00000509990.5
ENST00000506147.5
ENST00000512107.5
MATR3
matrin 3
chr19_-_39532809 1.06 ENST00000326282.5
EID2B
EP300 interacting inhibitor of differentiation 2B
chr6_+_30883085 1.01 ENST00000504651.5
ENST00000512694.5
ENST00000515233.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr6_+_30882914 1.00 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
DDR1
discoidin domain receptor tyrosine kinase 1
chr19_+_35030626 1.00 ENST00000638536.1
SCN1B
sodium voltage-gated channel beta subunit 1
chr10_-_71773513 0.98 ENST00000394957.8
VSIR
V-set immunoregulatory receptor
chr7_+_100483919 0.97 ENST00000300179.7
NYAP1
neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1
chr5_-_170297746 0.96 ENST00000046794.10
LCP2
lymphocyte cytosolic protein 2
chr1_+_159171607 0.95 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr11_-_83071819 0.94 ENST00000524635.1
ENST00000526205.5
ENST00000533486.5
ENST00000533276.6
ENST00000527633.6
RAB30
RAB30, member RAS oncogene family
chr1_+_160190567 0.94 ENST00000368078.8
CASQ1
calsequestrin 1
chr11_+_26332117 0.89 ENST00000531646.1
ENST00000256737.8
ANO3
anoctamin 3
chr19_+_35030438 0.89 ENST00000415950.5
ENST00000262631.11
SCN1B
sodium voltage-gated channel beta subunit 1
chr5_-_95081482 0.83 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr1_-_204494701 0.83 ENST00000429009.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr3_+_98531965 0.81 ENST00000284311.5
GPR15
G protein-coupled receptor 15
chr5_+_76083398 0.79 ENST00000322285.7
SV2C
synaptic vesicle glycoprotein 2C
chr10_-_124744280 0.78 ENST00000337318.8
FAM53B
family with sequence similarity 53 member B
chr11_-_83071917 0.76 ENST00000534141.5
RAB30
RAB30, member RAS oncogene family
chr2_-_2326378 0.76 ENST00000647618.1
MYT1L
myelin transcription factor 1 like
chrX_+_153072454 0.75 ENST00000421798.5
PNMA6A
PNMA family member 6A
chr5_+_76083360 0.74 ENST00000502798.7
SV2C
synaptic vesicle glycoprotein 2C
chr4_-_46388713 0.74 ENST00000507069.5
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr11_+_123358416 0.70 ENST00000638157.1
GRAMD1B
GRAM domain containing 1B
chr3_-_195442977 0.68 ENST00000326793.11
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr16_+_67567891 0.59 ENST00000642847.1
CTCF
CCCTC-binding factor
chr13_-_48037934 0.58 ENST00000646804.1
ENST00000643246.1
SUCLA2
succinate-CoA ligase ADP-forming subunit beta
chr11_+_64924673 0.57 ENST00000164133.7
ENST00000532850.1
PPP2R5B
protein phosphatase 2 regulatory subunit B'beta
chr7_-_127585566 0.55 ENST00000321407.3
GCC1
GRIP and coiled-coil domain containing 1
chr10_+_68560317 0.54 ENST00000373644.5
TET1
tet methylcytosine dioxygenase 1
chr1_-_204494752 0.53 ENST00000684373.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr19_-_6670117 0.52 ENST00000245912.7
TNFSF14
TNF superfamily member 14
chr12_-_119803383 0.52 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
CIT
citron rho-interacting serine/threonine kinase
chr20_+_56412249 0.49 ENST00000679887.1
ENST00000434344.2
CASS4
Cas scaffold protein family member 4
chr19_-_48993300 0.49 ENST00000323798.8
ENST00000263276.6
GYS1
glycogen synthase 1
chr19_-_55038256 0.48 ENST00000417454.5
ENST00000310373.7
ENST00000333884.2
GP6
glycoprotein VI platelet
chr12_-_119804298 0.46 ENST00000678652.1
ENST00000678494.1
CIT
citron rho-interacting serine/threonine kinase
chr19_-_6670151 0.45 ENST00000675206.1
TNFSF14
TNF superfamily member 14
chr20_-_63572455 0.44 ENST00000467148.1
HELZ2
helicase with zinc finger 2
chrX_+_11758159 0.44 ENST00000361672.6
ENST00000337339.7
ENST00000647869.1
ENST00000312196.10
ENST00000647857.1
ENST00000649130.1
MSL3
MSL complex subunit 3
chr20_+_56412112 0.43 ENST00000360314.7
CASS4
Cas scaffold protein family member 4
chr8_-_19757924 0.43 ENST00000523262.5
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_-_130916437 0.41 ENST00000533214.1
ENST00000528555.5
ENST00000530356.5
ENST00000265909.9
SNX19
sorting nexin 19
chr4_-_73069696 0.40 ENST00000507544.3
ENST00000295890.8
COX18
cytochrome c oxidase assembly factor COX18
chr9_+_71911615 0.37 ENST00000334731.7
ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr16_-_68372258 0.37 ENST00000568373.5
ENST00000563226.1
SMPD3
sphingomyelin phosphodiesterase 3
chr17_+_77127865 0.36 ENST00000586429.5
SEC14L1
SEC14 like lipid binding 1
chr7_-_55538653 0.36 ENST00000625836.2
VOPP1
VOPP1 WW domain binding protein
chr16_-_19884828 0.36 ENST00000300571.7
ENST00000570142.5
ENST00000562469.5
GPRC5B
G protein-coupled receptor class C group 5 member B
chr18_+_12407896 0.35 ENST00000590956.5
ENST00000336990.8
ENST00000440960.6
ENST00000588729.5
PRELID3A
PRELI domain containing 3A
chr8_-_42768602 0.33 ENST00000534622.5
CHRNA6
cholinergic receptor nicotinic alpha 6 subunit
chr5_+_75512058 0.32 ENST00000514296.5
POLK
DNA polymerase kappa
chr1_+_209827964 0.32 ENST00000491415.7
UTP25
UTP25 small subunit processor component
chr16_+_89720980 0.30 ENST00000289816.9
ENST00000568064.5
ZNF276
zinc finger protein 276
chr4_+_158315309 0.30 ENST00000460056.6
RXFP1
relaxin family peptide receptor 1
chr20_+_56412393 0.29 ENST00000679529.1
CASS4
Cas scaffold protein family member 4
chr5_-_75511596 0.28 ENST00000643158.1
ENST00000261415.12
ENST00000646713.1
ENST00000643773.1
ENST00000645866.1
ENST00000644072.2
ENST00000643780.2
ENST00000645483.1
ENST00000642556.1
ENST00000646511.1
CERT1
ceramide transporter 1
chr21_+_43789522 0.28 ENST00000497547.2
RRP1
ribosomal RNA processing 1
chr4_-_5893075 0.28 ENST00000324989.12
CRMP1
collapsin response mediator protein 1
chr7_+_23680130 0.28 ENST00000409192.7
ENST00000409653.5
ENST00000409994.3
ENST00000344962.9
FAM221A
family with sequence similarity 221 member A
chr16_+_30023198 0.28 ENST00000681219.1
ENST00000300575.6
C16orf92
chromosome 16 open reading frame 92
chr17_+_47941506 0.26 ENST00000583599.6
PNPO
pyridoxamine 5'-phosphate oxidase
chr19_+_52274443 0.26 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
ZNF766
zinc finger protein 766
chr19_+_39436149 0.25 ENST00000594990.5
SUPT5H
SPT5 homolog, DSIF elongation factor subunit
chr6_+_29306626 0.24 ENST00000377160.4
OR14J1
olfactory receptor family 14 subfamily J member 1
chr1_+_171781635 0.24 ENST00000361735.4
ENST00000362019.7
ENST00000367737.9
EEF1AKNMT
eEF1A lysine and N-terminal methyltransferase
chr15_+_32030506 0.23 ENST00000306901.9
ENST00000636440.1
CHRNA7
cholinergic receptor nicotinic alpha 7 subunit
chr1_-_120051714 0.23 ENST00000579475.7
NOTCH2
notch receptor 2
chr1_-_156053780 0.23 ENST00000368309.4
UBQLN4
ubiquilin 4
chr10_+_49609095 0.22 ENST00000339797.5
CHAT
choline O-acetyltransferase
chr9_+_123033660 0.21 ENST00000616002.3
GPR21
G protein-coupled receptor 21
chrX_-_57680260 0.21 ENST00000434992.1
NLRP2B
NLR family pyrin domain containing 2B
chr9_+_104504263 0.19 ENST00000334726.3
OR13F1
olfactory receptor family 13 subfamily F member 1
chrX_+_135032346 0.18 ENST00000257013.9
RTL8C
retrotransposon Gag like 8C
chr8_-_42768781 0.18 ENST00000276410.7
CHRNA6
cholinergic receptor nicotinic alpha 6 subunit
chr17_-_5584448 0.18 ENST00000269280.8
ENST00000571451.6
ENST00000572272.6
ENST00000613500.4
ENST00000619223.4
ENST00000617618.4
ENST00000345221.7
ENST00000262467.10
NLRP1
NLR family pyrin domain containing 1
chr2_-_74343397 0.18 ENST00000394019.6
ENST00000377634.8
ENST00000436454.1
SLC4A5
solute carrier family 4 member 5
chr16_-_58734299 0.18 ENST00000245206.10
ENST00000434819.2
GOT2
glutamic-oxaloacetic transaminase 2
chr5_+_77086682 0.17 ENST00000643365.1
ENST00000645183.1
ENST00000645374.1
ENST00000647364.1
ENST00000643848.1
ENST00000643603.1
ENST00000645459.1
ENST00000643269.1
ENST00000503969.6
ENST00000646262.1
ZBED3-AS1
ENSG00000284762.1
ZBED3 antisense RNA 1
phosphodiesterase 8B
chr5_-_95081858 0.17 ENST00000505465.1
MCTP1
multiple C2 and transmembrane domain containing 1
chr2_-_153478753 0.17 ENST00000325926.4
RPRM
reprimo, TP53 dependent G2 arrest mediator homolog
chr1_-_166166973 0.17 ENST00000354422.4
FAM78B
family with sequence similarity 78 member B
chr2_-_110212519 0.14 ENST00000611969.5
MTLN
mitoregulin
chr9_+_71911468 0.14 ENST00000377031.7
C9orf85
chromosome 9 open reading frame 85
chr16_-_2135898 0.12 ENST00000262304.9
ENST00000423118.5
PKD1
polycystin 1, transient receptor potential channel interacting
chr10_-_75109106 0.11 ENST00000607487.5
DUSP13
dual specificity phosphatase 13
chrX_+_70234655 0.10 ENST00000374521.4
AWAT1
acyl-CoA wax alcohol acyltransferase 1
chr1_-_155300933 0.10 ENST00000434082.3
PKLR
pyruvate kinase L/R
chr7_+_143935233 0.09 ENST00000408955.3
OR2F2
olfactory receptor family 2 subfamily F member 2
chr20_-_56497608 0.08 ENST00000617620.1
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr2_+_240691851 0.07 ENST00000429564.1
ENST00000337801.9
AQP12A
aquaporin 12A
chr8_+_38404363 0.06 ENST00000527175.1
LETM2
leucine zipper and EF-hand containing transmembrane protein 2
chr15_+_64136330 0.06 ENST00000560861.1
SNX1
sorting nexin 1
chr12_+_27466810 0.05 ENST00000298876.8
ENST00000416383.5
SMCO2
single-pass membrane protein with coiled-coil domains 2
chrX_-_386900 0.04 ENST00000390665.9
PPP2R3B
protein phosphatase 2 regulatory subunit B''beta
chr5_-_83673544 0.04 ENST00000503117.1
ENST00000510978.5
HAPLN1
hyaluronan and proteoglycan link protein 1
chr5_-_175968280 0.03 ENST00000513482.1
ENST00000265097.9
ENST00000628318.2
THOC3
THO complex 3
chr10_-_75109172 0.02 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
DUSP13
dual specificity phosphatase 13
chr10_-_75109085 0.01 ENST00000607131.5
DUSP13
dual specificity phosphatase 13
chr14_-_106803221 0.01 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr13_+_27424583 0.01 ENST00000381140.10
GTF3A
general transcription factor IIIA
chr14_-_106579223 0.00 ENST00000390626.2
IGHV5-51
immunoglobulin heavy variable 5-51
chr11_+_67240047 0.00 ENST00000530342.2
KDM2A
lysine demethylase 2A
chr19_-_3772211 0.00 ENST00000555978.5
ENST00000555633.3
RAX2
retina and anterior neural fold homeobox 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.4 2.6 GO:0032571 response to vitamin K(GO:0032571)
0.3 1.9 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.3 1.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.3 2.7 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 1.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 0.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.6 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 2.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 1.3 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 2.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 2.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.6 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 0.9 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 2.7 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.3 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 1.8 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.2 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.1 0.2 GO:0006533 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 2.9 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.4 GO:0015871 choline transport(GO:0015871)
0.0 1.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.8 GO:0072678 T cell migration(GO:0072678)
0.0 0.8 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 4.2 GO:0030168 platelet activation(GO:0030168)
0.0 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0036398 TCR signalosome(GO:0036398)
0.2 0.9 GO:0014802 terminal cisterna(GO:0014802)
0.1 2.7 GO:0033010 paranodal junction(GO:0033010)
0.1 3.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0032044 DSIF complex(GO:0032044)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 5.4 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.4 1.9 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.6 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.6 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 2.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 2.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 2.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.3 GO:0004733 pyridoxamine-phosphate oxidase activity(GO:0004733)
0.1 0.4 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.2 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 1.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 1.5 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 2.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 3.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 1.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor