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Illumina Body Map 2 (GSE30611)

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Results for ZIC2_GLI1

Z-value: 1.69

Motif logo

Transcription factors associated with ZIC2_GLI1

Gene Symbol Gene ID Gene Info
ENSG00000043355.12 Zic family member 2
ENSG00000111087.10 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI1hg38_v1_chr12_+_57460127_574601510.163.9e-01Click!
ZIC2hg38_v1_chr13_+_99981775_999817910.086.5e-01Click!

Activity profile of ZIC2_GLI1 motif

Sorted Z-values of ZIC2_GLI1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_111913195 14.32 ENST00000531198.5
ENST00000616970.5
ENST00000527899.6
crystallin alpha B
chr11_-_111913134 12.92 ENST00000533971.2
ENST00000526180.6
crystallin alpha B
chr19_+_44809089 12.00 ENST00000270233.12
ENST00000591520.6
basal cell adhesion molecule (Lutheran blood group)
chr19_+_44809053 11.81 ENST00000611077.5
basal cell adhesion molecule (Lutheran blood group)
chr1_+_46798998 10.30 ENST00000640628.1
ENST00000271153.8
ENST00000371923.9
ENST00000371919.8
ENST00000614163.4
cytochrome P450 family 4 subfamily B member 1
chr5_-_168883333 10.26 ENST00000404867.7
slit guidance ligand 3
chr4_+_165378998 9.90 ENST00000402744.9
carboxypeptidase E
chr11_+_111912725 9.35 ENST00000304298.4
heat shock protein family B (small) member 2
chr11_-_111912871 8.46 ENST00000528628.5
crystallin alpha B
chr5_-_169300782 8.15 ENST00000332966.8
slit guidance ligand 3
chr3_-_73624840 7.36 ENST00000308537.4
ENST00000263666.9
PDZ domain containing ring finger 3
chr21_-_26843063 7.23 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr19_+_676385 7.13 ENST00000166139.9
follistatin like 3
chr21_-_26843012 7.01 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr4_-_5019437 6.09 ENST00000506508.1
ENST00000509419.1
ENST00000307746.9
cytokine like 1
chr8_+_19939246 5.71 ENST00000650287.1
lipoprotein lipase
chr20_+_37521206 5.65 ENST00000346199.3
ENST00000647955.1
ENST00000649451.1
ENST00000649697.1
ENST00000649309.1
neuronatin
chr16_+_31472130 5.65 ENST00000394863.8
ENST00000565360.5
ENST00000361773.7
transforming growth factor beta 1 induced transcript 1
chr1_-_39639626 5.63 ENST00000372852.4
hes related family bHLH transcription factor with YRPW motif like
chr8_-_17697654 5.20 ENST00000297488.10
microtubule associated scaffold protein 1
chr21_-_26573211 5.08 ENST00000299340.9
ENST00000652641.2
cysteine and tyrosine rich 1
chr5_+_72107453 4.79 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr2_+_26692686 4.57 ENST00000620977.1
ENST00000302909.4
potassium two pore domain channel subfamily K member 3
chr3_+_154121366 4.23 ENST00000465093.6
ENST00000496710.5
ENST00000465817.1
Rho guanine nucleotide exchange factor 26
chr3_+_50269140 4.21 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr11_+_118607598 4.17 ENST00000600882.6
ENST00000356063.9
pleckstrin homology like domain family B member 1
chr20_+_44714835 4.02 ENST00000372868.6
cellular communication network factor 5
chr11_-_12008584 3.90 ENST00000534511.5
ENST00000683431.1
dickkopf WNT signaling pathway inhibitor 3
chr17_+_7023042 3.89 ENST00000293805.10
BCL6B transcription repressor
chr5_-_122077152 3.71 ENST00000513319.5
ENST00000503759.5
lysyl oxidase
chr1_-_171652675 3.65 ENST00000037502.11
myocilin
chr3_+_170418856 3.53 ENST00000064724.8
ENST00000486975.1
claudin 11
novel protein
chr8_+_30387064 3.52 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr11_-_11621991 3.52 ENST00000227756.5
polypeptide N-acetylgalactosaminyltransferase 18
chr11_-_111911759 3.47 ENST00000650687.2
crystallin alpha B
chr20_+_44714853 3.45 ENST00000372865.4
cellular communication network factor 5
chr22_-_42720861 3.40 ENST00000642412.2
alpha 1,4-galactosyltransferase (P blood group)
chr21_-_26845402 3.39 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr10_-_88952763 3.31 ENST00000224784.10
actin alpha 2, smooth muscle
chr22_-_42720813 3.28 ENST00000381278.4
alpha 1,4-galactosyltransferase (P blood group)
chrX_+_91434829 3.27 ENST00000312600.4
poly(A) binding protein cytoplasmic 5
chr7_+_130492066 3.26 ENST00000223215.10
ENST00000437945.6
mesoderm specific transcript
chr20_+_63696643 3.23 ENST00000369996.3
TNF receptor superfamily member 6b
chr17_-_35795592 3.13 ENST00000615136.4
ENST00000605424.6
ENST00000612672.1
matrix metallopeptidase 28
chr17_-_76537699 3.02 ENST00000293230.10
cytoglobin
chr17_+_62627628 3.02 ENST00000303375.10
mannose receptor C type 2
chr11_-_8593940 2.99 ENST00000315204.5
ENST00000396672.5
ENST00000431279.6
ENST00000418597.5
serine/threonine kinase 33
chr17_+_42682470 2.84 ENST00000264638.9
contactin associated protein 1
chr2_+_158968608 2.80 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr19_-_40413364 2.76 ENST00000291825.11
ENST00000324001.8
periaxin
chr14_+_64540734 2.72 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr5_-_142325001 2.71 ENST00000344120.4
ENST00000434127.3
sprouty RTK signaling antagonist 4
chr5_-_44389407 2.71 ENST00000264664.5
fibroblast growth factor 10
chr10_+_80413817 2.70 ENST00000372187.9
peroxiredoxin like 2A
chr2_+_216633411 2.68 ENST00000233809.9
insulin like growth factor binding protein 2
chr22_-_19524400 2.59 ENST00000618236.2
claudin 5
chrX_-_17861236 2.52 ENST00000331511.5
ENST00000415486.7
ENST00000451717.6
ENST00000545871.1
retinoic acid induced 2
chr1_-_205813177 2.40 ENST00000367137.4
solute carrier family 41 member 1
chr19_-_42253888 2.39 ENST00000593944.5
ETS2 repressor factor
chr11_-_75668566 2.37 ENST00000526740.3
microtubule associated protein 6
chr19_-_35135011 2.34 ENST00000310123.8
leucine rich repeat LGI family member 4
chr16_-_21440719 2.30 ENST00000521589.5
nuclear pore complex interacting protein family member B3
chr21_-_26573145 2.23 ENST00000400043.3
cysteine and tyrosine rich 1
chr8_+_74824526 2.21 ENST00000649643.1
ENST00000260113.7
peptidase inhibitor 15
chr2_-_85663393 2.19 ENST00000494165.1
surfactant protein B
chr1_-_182604379 2.19 ENST00000367558.6
regulator of G protein signaling 16
chr17_-_76537630 2.15 ENST00000589342.1
cytoglobin
chr19_-_35134861 2.10 ENST00000591633.2
leucine rich repeat LGI family member 4
chr16_+_28863946 2.09 ENST00000395532.8
SH2B adaptor protein 1
chr9_+_106863121 2.04 ENST00000472574.1
ENST00000277225.10
zinc finger protein 462
chr4_-_186596770 1.99 ENST00000512772.5
FAT atypical cadherin 1
chr9_-_122227525 1.96 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr22_+_31093358 1.95 ENST00000404574.5
smoothelin
chr5_+_53480619 1.95 ENST00000396947.7
ENST00000256759.8
follistatin
chr1_-_44843240 1.89 ENST00000372192.4
patched 2
chr9_+_128411715 1.89 ENST00000420034.5
ENST00000372842.5
cerebral endothelial cell adhesion molecule
chr10_-_93601228 1.85 ENST00000371464.8
retinol binding protein 4
chr11_-_64759967 1.80 ENST00000377432.7
ENST00000164139.4
glycogen phosphorylase, muscle associated
chr7_+_116672187 1.75 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr7_-_82443715 1.71 ENST00000356253.9
ENST00000423588.1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr6_-_29633171 1.69 ENST00000377034.9
gamma-aminobutyric acid type B receptor subunit 1
chrX_-_17860707 1.69 ENST00000360011.5
retinoic acid induced 2
chr1_+_183186238 1.68 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr1_-_183418364 1.67 ENST00000287713.7
nicotinamide nucleotide adenylyltransferase 2
chr11_+_76782250 1.65 ENST00000533752.1
ENST00000612930.1
tsukushi, small leucine rich proteoglycan
chr6_-_29633056 1.64 ENST00000377016.8
gamma-aminobutyric acid type B receptor subunit 1
chr6_+_36948257 1.61 ENST00000647861.1
ENST00000611814.4
peptidase inhibitor 16
chr17_-_7234262 1.61 ENST00000575756.5
ENST00000575458.5
dishevelled segment polarity protein 2
chr10_-_95290992 1.61 ENST00000329399.7
PDZ and LIM domain 1
chr7_+_90403386 1.61 ENST00000287916.8
ENST00000394604.5
ENST00000496677.6
ENST00000394605.2
ENST00000480135.1
claudin 12
novel transcript
chr11_-_75668434 1.58 ENST00000434603.2
microtubule associated protein 6
chr6_+_43771960 1.55 ENST00000230480.10
vascular endothelial growth factor A
chr9_-_34397800 1.52 ENST00000297623.7
chromosome 9 open reading frame 24
chr11_+_118607579 1.52 ENST00000530708.4
pleckstrin homology like domain family B member 1
chr9_+_113349514 1.49 ENST00000374183.5
B-box and SPRY domain containing
chr12_-_6688859 1.48 ENST00000542351.5
ENST00000538829.5
zinc finger protein 384
chr1_-_85465147 1.47 ENST00000284031.13
dimethylarginine dimethylaminohydrolase 1
chr10_-_75401746 1.46 ENST00000372524.5
zinc finger protein 503
chr3_-_9878765 1.46 ENST00000430427.6
ENST00000383817.5
ENST00000679265.1
cell death inducing DFFA like effector c
chr3_+_137998735 1.45 ENST00000343735.8
claudin 18
chr9_-_127877665 1.42 ENST00000644144.2
adenylate kinase 1
chr11_-_12009082 1.40 ENST00000396505.7
dickkopf WNT signaling pathway inhibitor 3
chr10_+_134465 1.40 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
zinc finger MYND-type containing 11
chr11_-_12009134 1.38 ENST00000529338.1
dickkopf WNT signaling pathway inhibitor 3
chr3_+_159764002 1.37 ENST00000460298.3
IQCJ-SCHIP1 readthrough
chr4_-_185775271 1.35 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr10_-_34815257 1.34 ENST00000374789.8
ENST00000374788.8
ENST00000346874.9
ENST00000374794.8
ENST00000350537.9
ENST00000374790.8
ENST00000374776.6
ENST00000374773.6
ENST00000545260.5
ENST00000545693.5
ENST00000340077.9
par-3 family cell polarity regulator
chr5_+_80960694 1.34 ENST00000638442.1
Ras protein specific guanine nucleotide releasing factor 2
chr7_-_108456378 1.33 ENST00000613830.4
ENST00000413765.6
ENST00000379028.8
neuronal cell adhesion molecule
chr3_+_113897470 1.33 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr7_-_108456321 1.33 ENST00000379024.8
ENST00000351718.8
neuronal cell adhesion molecule
chr15_+_39581068 1.29 ENST00000397591.2
ENST00000260356.6
thrombospondin 1
chr22_+_37805218 1.27 ENST00000340857.4
H1.0 linker histone
chrX_+_51893533 1.26 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr17_-_7234462 1.25 ENST00000005340.10
dishevelled segment polarity protein 2
chr2_+_24793394 1.23 ENST00000380834.7
ENST00000260662.2
centromere protein O
chr17_+_7023062 1.21 ENST00000576705.1
BCL6B transcription repressor
chr6_-_29628038 1.20 ENST00000355973.7
ENST00000377012.8
gamma-aminobutyric acid type B receptor subunit 1
chr4_-_185775890 1.15 ENST00000437304.6
sorbin and SH3 domain containing 2
chr7_-_151410024 1.15 ENST00000628331.1
ENST00000334493.11
WD repeat domain 86
chr8_+_42152946 1.14 ENST00000518421.5
ENST00000174653.3
ENST00000396926.8
ENST00000521280.5
ENST00000522288.5
adaptor related protein complex 3 subunit mu 2
chr6_+_162727941 1.13 ENST00000366888.6
parkin coregulated
chr22_-_30387078 1.12 ENST00000215798.10
ring finger protein 215
chr2_+_136765508 1.11 ENST00000409968.6
thrombospondin type 1 domain containing 7B
chr12_-_6689244 1.08 ENST00000361959.7
ENST00000436774.6
ENST00000544482.1
zinc finger protein 384
chr5_+_72107234 1.08 ENST00000512974.5
microtubule associated protein 1B
chr4_+_76949743 1.07 ENST00000502584.5
ENST00000264893.11
ENST00000510641.5
septin 11
chr9_+_34990250 1.06 ENST00000454002.6
ENST00000545841.5
DnaJ heat shock protein family (Hsp40) member B5
chr12_-_106084023 1.06 ENST00000553094.1
ENST00000549704.1
NUAK family kinase 1
chr3_-_24495532 1.02 ENST00000643772.1
ENST00000642307.1
ENST00000645139.1
thyroid hormone receptor beta
chr15_-_93073706 1.02 ENST00000425933.6
repulsive guidance molecule BMP co-receptor a
chr18_+_23949847 1.01 ENST00000588004.1
laminin subunit alpha 3
chr4_+_76949807 1.00 ENST00000505788.5
ENST00000510515.5
ENST00000504637.5
septin 11
chr3_+_138010143 0.99 ENST00000183605.10
claudin 18
chr11_+_57761787 0.98 ENST00000358694.10
ENST00000361332.8
ENST00000361391.10
ENST00000361796.9
ENST00000415361.6
ENST00000426142.6
ENST00000428599.6
ENST00000525902.5
ENST00000526357.5
ENST00000526772.5
ENST00000527467.5
ENST00000528232.5
ENST00000528621.5
ENST00000529526.5
ENST00000529873.5
ENST00000529986.5
ENST00000530094.5
ENST00000530748.5
ENST00000531014.5
ENST00000532245.5
ENST00000532463.5
ENST00000532649.5
ENST00000532787.5
ENST00000532844.5
ENST00000533667.5
ENST00000534579.5
ENST00000399050.10
ENST00000526938.5
ENST00000674015.1
ENST00000531007.2
ENST00000673826.1
catenin delta 1
chr17_+_7705193 0.97 ENST00000226091.3
ephrin B3
chr22_-_45977154 0.97 ENST00000339464.9
Wnt family member 7B
chrX_+_71144818 0.96 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
neuroligin 3
chr1_-_43367956 0.95 ENST00000372458.8
ELOVL fatty acid elongase 1
chr2_+_24793098 0.95 ENST00000473706.5
centromere protein O
chr5_-_90409720 0.94 ENST00000522864.5
ENST00000283122.8
ENST00000522083.5
ENST00000522565.5
ENST00000522842.1
centrin 3
chr10_-_79444216 0.91 ENST00000372333.3
zinc finger CCHC-type containing 24
chr9_+_34989641 0.91 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chr10_+_24466487 0.90 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr6_-_110179623 0.90 ENST00000265601.7
ENST00000447287.5
ENST00000392589.6
ENST00000444391.5
WASP family member 1
chr6_+_125219804 0.88 ENST00000524679.1
TPD52 like 1
chr3_+_4493471 0.88 ENST00000544951.6
ENST00000650294.1
inositol 1,4,5-trisphosphate receptor type 1
chr4_-_89837106 0.88 ENST00000394986.5
ENST00000394991.8
ENST00000506244.5
ENST00000394989.6
ENST00000673902.1
ENST00000674129.1
synuclein alpha
chr17_-_31858952 0.87 ENST00000378634.6
coordinator of PRMT5 and differentiation stimulator
chr17_+_76001338 0.86 ENST00000425876.6
cyclin dependent kinase 3
chr17_+_7886178 0.86 ENST00000672274.1
chromodomain helicase DNA binding protein 3
chr16_-_85112390 0.85 ENST00000629253.1
ENST00000539556.6
CBY1 interacting BAR domain containing 2
chr12_-_6689450 0.84 ENST00000355772.8
ENST00000417772.7
ENST00000319770.7
ENST00000396801.7
zinc finger protein 384
chr17_+_48054675 0.84 ENST00000582155.5
ENST00000583378.5
ENST00000536222.5
nuclear factor, erythroid 2 like 1
chrX_+_54809060 0.84 ENST00000396224.1
MAGE family member D2
chr22_-_27801712 0.84 ENST00000302326.5
MN1 proto-oncogene, transcriptional regulator
chr9_-_113340248 0.83 ENST00000341761.8
ENST00000374195.7
ENST00000374193.9
WD repeat domain 31
chr9_-_122228845 0.83 ENST00000394319.8
ENST00000340587.7
LIM homeobox 6
chr5_-_149379286 0.81 ENST00000261796.4
interleukin 17B
chr17_+_7884783 0.81 ENST00000380358.9
chromodomain helicase DNA binding protein 3
chr19_+_3314403 0.80 ENST00000641145.1
nuclear factor I C
chrX_-_139204275 0.79 ENST00000441825.8
fibroblast growth factor 13
chr9_-_33264559 0.79 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG cochaperone 1
chr4_+_71187269 0.78 ENST00000425175.5
ENST00000351898.10
solute carrier family 4 member 4
chr16_+_86578543 0.77 ENST00000320241.5
forkhead box L1
chr3_-_185824966 0.74 ENST00000457616.6
ENST00000346192.7
insulin like growth factor 2 mRNA binding protein 2
chr9_+_40223317 0.73 ENST00000611747.1
ENST00000377601.3
ENST00000654136.1
ENST00000659103.1
ankyrin repeat domain 20 family member A2, pseudogene
novel transcript
chr16_+_55324191 0.72 ENST00000290552.8
iroquois homeobox 6
chr11_+_45146631 0.69 ENST00000534751.3
ENST00000683152.1
PR/SET domain 11
chr12_-_6689359 0.69 ENST00000683879.1
zinc finger protein 384
chr11_-_19201976 0.68 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
cysteine and glycine rich protein 3
chr11_-_120120880 0.67 ENST00000526881.1
tripartite motif containing 29
chrX_-_139205006 0.66 ENST00000436198.5
ENST00000626909.2
fibroblast growth factor 13
chr6_-_110179702 0.64 ENST00000392587.6
WASP family member 1
chr3_-_185825029 0.64 ENST00000382199.7
insulin like growth factor 2 mRNA binding protein 2
chrX_-_52069172 0.62 ENST00000486010.1
ENST00000497164.5
ENST00000360134.10
ENST00000485287.5
ENST00000335504.9
MAGE family member D4B
chr16_-_981259 0.60 ENST00000563837.1
ENST00000563863.5
ENST00000565069.5
ENST00000570014.5
cytoplasmic endogenous regulator of oxidative phosphorylation 1
lipase maturation factor 1
chr1_-_43368039 0.60 ENST00000413844.3
ELOVL fatty acid elongase 1
chr3_-_16512895 0.58 ENST00000449415.5
ENST00000441460.5
raftlin, lipid raft linker 1
chr10_+_134703 0.57 ENST00000509513.6
zinc finger MYND-type containing 11
chr4_-_185775432 0.57 ENST00000457247.5
ENST00000435480.5
ENST00000425679.5
ENST00000457934.5
sorbin and SH3 domain containing 2
chr17_+_48055945 0.56 ENST00000580037.1
nuclear factor, erythroid 2 like 1
chr1_-_43367689 0.56 ENST00000621943.4
ELOVL fatty acid elongase 1
chr2_+_68467544 0.55 ENST00000303795.9
aprataxin and PNKP like factor
chr2_-_132670194 0.54 ENST00000397463.3
LY6/PLAUR domain containing 1
chr9_+_132410183 0.53 ENST00000393216.3
ENST00000343036.6
cilia and flagella associated protein 77
chr12_+_4269771 0.52 ENST00000676411.1
cyclin D2
chr14_-_106211453 0.52 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr3_+_111071773 0.52 ENST00000485303.6
nectin cell adhesion molecule 3
chr9_+_33265013 0.52 ENST00000223500.9
charged multivesicular body protein 5
chr9_+_33264848 0.51 ENST00000419016.6
charged multivesicular body protein 5
chr7_+_90403506 0.51 ENST00000427904.1
claudin 12
chr19_-_12957198 0.50 ENST00000316939.3
GADD45G interacting protein 1
chr13_-_30306837 0.49 ENST00000414289.5
katanin catalytic subunit A1 like 1
chr9_-_113056670 0.49 ENST00000553380.1
ENST00000374227.8
ZFP37 zinc finger protein
chr1_+_6613722 0.48 ENST00000377648.5
PHD finger protein 13
chr8_-_41665261 0.48 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ankyrin 1
chr1_+_32209074 0.47 ENST00000409358.2
doublecortin domain containing 2B
chr4_+_61202142 0.47 ENST00000514591.5
adhesion G protein-coupled receptor L3
chr17_+_75093287 0.46 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC2_GLI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 18.4 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
2.6 10.3 GO:0018879 biphenyl metabolic process(GO:0018879)
2.0 9.9 GO:0030070 insulin processing(GO:0030070)
1.7 39.2 GO:0007021 tubulin complex assembly(GO:0007021)
1.3 6.7 GO:0001575 globoside metabolic process(GO:0001575)
0.9 3.7 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.9 2.7 GO:0060876 semicircular canal formation(GO:0060876) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.8 6.7 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.8 17.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.7 2.9 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.7 5.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.6 5.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.6 5.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.6 5.6 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.6 3.3 GO:0090131 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.5 3.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.5 1.6 GO:1903570 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.5 1.0 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.5 5.7 GO:0009249 protein lipoylation(GO:0009249)
0.4 5.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.4 1.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.4 1.7 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.4 9.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 1.9 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.3 1.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 2.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.3 3.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 5.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 10.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 6.8 GO:0070831 basement membrane assembly(GO:0070831)
0.2 1.7 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 1.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 6.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.2 1.5 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 2.8 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 1.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 2.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 4.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 1.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 6.0 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.8 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.7 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 2.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 1.0 GO:0008050 female courtship behavior(GO:0008050)
0.1 6.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 1.0 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 2.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.5 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.8 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 2.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.3 GO:0002086 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.1 0.6 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.1 4.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0006311 meiotic gene conversion(GO:0006311)
0.1 4.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 0.8 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 1.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 1.0 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 1.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 6.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.3 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) CUT metabolic process(GO:0071043)
0.1 2.7 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.6 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 2.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 2.9 GO:0042092 type 2 immune response(GO:0042092)
0.0 1.8 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.4 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.3 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 16.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.6 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 1.1 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 1.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0060667 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 1.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.6 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 8.3 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 2.1 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 2.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 2.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 2.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 1.4 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 2.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.5 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 3.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 2.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 1.5 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 1.4 GO:0032418 lysosome localization(GO:0032418)
0.0 4.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.5 GO:0007498 mesoderm development(GO:0007498)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 39.2 GO:0097512 cardiac myofibril(GO:0097512)
0.9 4.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 3.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 5.1 GO:0045180 basal cortex(GO:0045180)
0.2 2.7 GO:0072687 meiotic spindle(GO:0072687)
0.2 5.7 GO:0042627 chylomicron(GO:0042627)
0.2 2.5 GO:0043194 axon initial segment(GO:0043194)
0.2 2.7 GO:0043256 laminin complex(GO:0043256)
0.2 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 2.8 GO:0033010 paranodal junction(GO:0033010)
0.2 2.2 GO:0097486 alveolar lamellar body(GO:0097208) multivesicular body lumen(GO:0097486)
0.1 1.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.3 GO:0033269 internode region of axon(GO:0033269)
0.1 3.5 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 3.7 GO:0033268 node of Ranvier(GO:0033268)
0.1 16.0 GO:0005604 basement membrane(GO:0005604)
0.1 6.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 6.0 GO:0031594 neuromuscular junction(GO:0031594)
0.1 5.1 GO:0045178 basal part of cell(GO:0045178)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 2.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.0 GO:0005915 zonula adherens(GO:0005915)
0.0 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 5.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 3.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 17.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 9.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 6.7 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.8 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 3.6 GO:0005581 collagen trimer(GO:0005581)
0.0 50.3 GO:0005615 extracellular space(GO:0005615)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.2 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 3.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 23.8 GO:0005055 laminin receptor activity(GO:0005055)
2.4 24.1 GO:0048495 Roundabout binding(GO:0048495)
1.9 5.7 GO:0017129 triglyceride binding(GO:0017129)
1.4 5.6 GO:0035939 microsatellite binding(GO:0035939)
1.3 5.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
1.2 37.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.8 18.2 GO:0015643 toxic substance binding(GO:0015643)
0.8 4.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 3.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.6 1.7 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.5 2.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.5 1.8 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.4 1.7 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.4 3.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.4 9.1 GO:0048185 activin binding(GO:0048185)
0.4 9.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 1.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 3.7 GO:0032027 myosin light chain binding(GO:0032027)
0.3 1.3 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.2 1.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 2.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 2.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 3.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 3.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 20.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 4.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 4.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0035500 MH2 domain binding(GO:0035500)
0.1 1.9 GO:0019841 retinol binding(GO:0019841)
0.1 2.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 3.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.8 GO:0005109 frizzled binding(GO:0005109)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 1.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.8 GO:0031433 telethonin binding(GO:0031433)
0.0 2.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 1.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 2.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 3.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.0 GO:0005518 collagen binding(GO:0005518)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.0 3.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 6.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 4.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 10.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 23.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 18.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.7 ST GAQ PATHWAY G alpha q Pathway
0.0 3.3 PID BMP PATHWAY BMP receptor signaling
0.0 4.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 6.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 12.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 5.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 17.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 3.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 10.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.5 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 3.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 5.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK