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Illumina Body Map 2 (GSE30611)

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Results for ZNF274

Z-value: 0.57

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Transcription factors associated with ZNF274

Gene Symbol Gene ID Gene Info
ZNF274
ENSG00000171606.18 zinc finger protein 274

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF274hg38_v1_chr19_+_58183375_581834940.261.5e-01Click!

Activity profile of ZNF274 motif

Sorted Z-values of ZNF274 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_142391884 1.66 ENST00000390363.2
TRBV9
T cell receptor beta variable 9
chr14_+_21941122 1.63 ENST00000390441.2
TRAV9-2
T cell receptor alpha variable 9-2
chr20_-_1657762 1.57 ENST00000303415.7
ENST00000381583.6
SIRPG
signal regulatory protein gamma
chr1_-_15944348 1.40 ENST00000444358.1
ZBTB17
zinc finger and BTB domain containing 17
chr10_-_29522527 1.31 ENST00000632315.1
SVIL
supervillin
chr20_-_1657714 1.25 ENST00000216927.4
ENST00000344103.8
SIRPG
signal regulatory protein gamma
chr16_-_4752565 1.23 ENST00000588099.1
ENST00000588942.1
ENSG00000266994.1
ZNF500
novel transcript
zinc finger protein 500
chr22_+_23696400 1.01 ENST00000452208.1
RGL4
ral guanine nucleotide dissociation stimulator like 4
chr2_-_88992903 0.98 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr6_+_31586124 0.97 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
LST1
leukocyte specific transcript 1
chr15_+_88621290 0.95 ENST00000332810.4
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr16_+_31458821 0.82 ENST00000457010.6
ENST00000563544.5
ARMC5
armadillo repeat containing 5
chr6_+_31586269 0.78 ENST00000438075.7
LST1
leukocyte specific transcript 1
chr16_+_29807775 0.72 ENST00000568411.5
ENST00000563012.1
ENST00000562557.5
MAZ
MYC associated zinc finger protein
chr16_+_29808125 0.70 ENST00000568282.1
MAZ
MYC associated zinc finger protein
chr16_+_29808051 0.68 ENST00000568544.5
ENST00000569978.1
MAZ
MYC associated zinc finger protein
chr6_+_36197356 0.67 ENST00000446974.1
ENST00000454960.1
BRPF3
bromodomain and PHD finger containing 3
chr16_+_29807536 0.67 ENST00000567444.5
MAZ
MYC associated zinc finger protein
chr10_+_69278492 0.64 ENST00000643399.2
HK1
hexokinase 1
chr1_-_113871665 0.62 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
PTPN22
protein tyrosine phosphatase non-receptor type 22
chr22_+_38957522 0.51 ENST00000618553.1
ENST00000249116.7
APOBEC3A
apolipoprotein B mRNA editing enzyme catalytic subunit 3A
chr3_+_128153422 0.44 ENST00000254730.11
ENST00000483457.1
EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA specific
chr17_-_3557798 0.43 ENST00000301365.8
ENST00000572519.1
ENST00000576742.6
TRPV3
transient receptor potential cation channel subfamily V member 3
chrX_-_142205260 0.39 ENST00000247452.4
MAGEC2
MAGE family member C2
chr1_+_44739825 0.38 ENST00000372224.9
KIF2C
kinesin family member 2C
chr19_+_6135635 0.37 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr19_-_55597753 0.36 ENST00000587678.1
FIZ1
FLT3 interacting zinc finger 1
chr16_+_10866247 0.34 ENST00000636238.1
CIITA
class II major histocompatibility complex transactivator
chr18_+_9885964 0.33 ENST00000357775.6
ENST00000306084.6
TXNDC2
thioredoxin domain containing 2
chr9_-_33473884 0.28 ENST00000297990.9
ENST00000353159.6
ENST00000379471.3
NOL6
nucleolar protein 6
chr21_+_39451963 0.27 ENST00000333634.10
SH3BGR
SH3 domain binding glutamate rich protein
chr2_+_236569817 0.26 ENST00000272928.4
ACKR3
atypical chemokine receptor 3
chr1_+_44739805 0.24 ENST00000452259.5
KIF2C
kinesin family member 2C
chr18_+_9885726 0.23 ENST00000611534.1
ENST00000536353.2
ENST00000584255.1
TXNDC2
thioredoxin domain containing 2
chr21_+_39452077 0.23 ENST00000452550.5
SH3BGR
SH3 domain binding glutamate rich protein
chr17_+_75032581 0.21 ENST00000581589.5
KCTD2
potassium channel tetramerization domain containing 2
chr11_+_59938432 0.21 ENST00000644529.1
ENST00000646685.1
OOSP1
oocyte secreted protein 1
chr6_+_30720335 0.19 ENST00000327892.13
TUBB
tubulin beta class I
chr5_+_122129597 0.19 ENST00000514925.1
ENSG00000250803.6
novel zinc finger protein
chr17_-_39166138 0.18 ENST00000269586.12
ARL5C
ADP ribosylation factor like GTPase 5C
chr8_-_4994696 0.16 ENST00000400186.7
ENST00000602723.5
CSMD1
CUB and Sushi multiple domains 1
chr18_+_9103959 0.15 ENST00000400033.1
NDUFV2
NADH:ubiquinone oxidoreductase core subunit V2
chr16_+_10866199 0.15 ENST00000637439.1
CIITA
class II major histocompatibility complex transactivator
chr19_-_42877988 0.15 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr9_+_93263948 0.14 ENST00000448251.5
WNK2
WNK lysine deficient protein kinase 2
chr1_-_53889766 0.14 ENST00000371399.5
ENST00000072644.7
YIPF1
Yip1 domain family member 1
chr19_-_19663664 0.13 ENST00000357324.11
ATP13A1
ATPase 13A1
chr5_-_173616588 0.10 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
BOD1
biorientation of chromosomes in cell division 1
chr3_+_50246888 0.10 ENST00000451956.1
GNAI2
G protein subunit alpha i2
chr19_+_57614211 0.09 ENST00000600344.1
ENST00000396161.10
ENST00000600883.1
ZNF134
zinc finger protein 134
chrX_+_16167481 0.08 ENST00000400004.6
MAGEB17
MAGE family member B17
chrX_+_16167713 0.07 ENST00000400003.1
MAGEB17
MAGE family member B17
chr11_+_19813704 0.05 ENST00000650578.1
NAV2
neuron navigator 2
chr19_+_39704461 0.04 ENST00000360675.7
ENST00000392052.8
ENST00000601802.1
LGALS14
galectin 14
chr12_+_55636892 0.04 ENST00000309675.3
OR10P1
olfactory receptor family 10 subfamily P member 1
chr11_+_89926762 0.04 ENST00000526396.3
TRIM49D2
tripartite motif containing 49D2
chr5_+_122129533 0.02 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
ZNF474
zinc finger protein 474
chr10_-_13761669 0.01 ENST00000650137.1
FRMD4A
FERM domain containing 4A
chr3_-_139044892 0.01 ENST00000413199.1
PRR23C
proline rich 23C
chrX_-_70260199 0.00 ENST00000374519.4
P2RY4
pyrimidinergic receptor P2Y4

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF274

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.5 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.4 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.1 0.6 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.6 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.5 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 1.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 2.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.8 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 2.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins