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Illumina Body Map 2 (GSE30611)

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Results for ZNF282

Z-value: 0.78

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ENSG00000170265.12 zinc finger protein 282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF282hg38_v1_chr7_+_149195537_149195559-0.301.0e-01Click!

Activity profile of ZNF282 motif

Sorted Z-values of ZNF282 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_168291599 2.75 ENST00000265293.9
WW and C2 domain containing 1
chr11_-_130428605 2.36 ENST00000257359.7
ADAM metallopeptidase with thrombospondin type 1 motif 8
chr14_-_36520222 2.31 ENST00000354822.7
NK2 homeobox 1
chr6_-_32184287 2.07 ENST00000375069.7
ENST00000375070.7
ENST00000438221.6
ENST00000620802.4
ENST00000538695.2
advanced glycosylation end-product specific receptor
chr6_-_32184243 1.94 ENST00000375055.6
ENST00000375076.9
advanced glycosylation end-product specific receptor
chr12_-_113403873 1.88 ENST00000552280.5
ENST00000257549.9
serine dehydratase
chr9_-_39874562 1.80 ENST00000622735.2

chr6_-_32184227 1.73 ENST00000450110.5
ENST00000375067.7
ENST00000375056.6
advanced glycosylation end-product specific receptor
chr1_+_26993684 1.49 ENST00000522111.3
TMF1 regulated nuclear protein 1
chrX_-_13817027 1.49 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chrX_-_13817346 1.47 ENST00000356942.9
glycoprotein M6B
chr1_+_2073462 1.36 ENST00000400921.6
protein kinase C zeta
chr2_+_231395702 1.36 ENST00000287590.6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr12_-_121858849 1.36 ENST00000289004.8
4-hydroxyphenylpyruvate dioxygenase
chr3_-_49869886 1.34 ENST00000296471.11
ENST00000488336.5
ENST00000477224.6
ENST00000467248.5
ENST00000466940.5
ENST00000463537.5
ENST00000480398.2
CaM kinase like vesicle associated
chr1_+_2073986 1.30 ENST00000461106.6
protein kinase C zeta
chr17_-_58527980 1.25 ENST00000583114.5
septin 4
chr22_+_45502832 1.15 ENST00000455233.5
ENST00000402984.7
ENST00000262722.11
ENST00000327858.11
ENST00000442170.6
ENST00000340923.9
fibulin 1
chrX_+_102712438 1.00 ENST00000486814.2
ENST00000535209.6
ENST00000543253.6
ENST00000332262.10
ENST00000483720.6
G protein-coupled receptor associated sorting protein 2
chr9_+_124015397 0.99 ENST00000488674.2
LIM homeobox 2
chr8_-_28490220 0.91 ENST00000517673.5
ENST00000380254.7
ENST00000518734.5
ENST00000346498.6
F-box protein 16
chr8_-_74321532 0.89 ENST00000342232.5
junctophilin 1
chr22_+_31082860 0.85 ENST00000619644.4
smoothelin
chr4_+_168832005 0.78 ENST00000393726.7
ENST00000507735.6
palladin, cytoskeletal associated protein
chr1_-_67134964 0.77 ENST00000684719.1
ENST00000603691.1
chromosome 1 open reading frame 141
chr17_+_39688079 0.74 ENST00000578199.5
erb-b2 receptor tyrosine kinase 2
chr11_+_83194249 0.70 ENST00000526731.5
ENST00000531895.5
ENST00000393392.6
ankyrin repeat domain 42
chrX_-_13817279 0.66 ENST00000475307.1
glycoprotein M6B
chr6_+_138796111 0.66 ENST00000367682.6
epithelial cell transforming 2 like
chr5_+_175872741 0.64 ENST00000502265.5
complexin 2
chr16_+_67170497 0.63 ENST00000563439.5
ENST00000268605.11
ENST00000564992.1
ENST00000564053.5
nucleolar protein 3
chr20_+_18288477 0.61 ENST00000377671.7
ENST00000360010.9
ENST00000628216.2
ENST00000425686.3
ENST00000434018.5
ENST00000630056.1
zinc finger protein 133
chr10_-_27746060 0.58 ENST00000375790.9
mohawk homeobox
chr10_+_11823348 0.57 ENST00000277570.10
ENST00000622831.4
proline and serine rich 2
chr11_+_63536801 0.56 ENST00000255688.8
ENST00000439013.6
phospholipase A and acyltransferase 4
chr11_+_66510626 0.56 ENST00000526815.5
ENST00000318312.12
ENST00000525809.5
ENST00000455748.6
ENST00000393994.4
ENST00000630659.2
Bardet-Biedl syndrome 1
chr4_+_51843063 0.55 ENST00000381441.7
ENST00000334635.10
defective in cullin neddylation 1 domain containing 4
chr8_-_109644766 0.55 ENST00000533065.5
ENST00000276646.14
syntabulin
chr6_+_128883114 0.55 ENST00000421865.3
ENST00000618192.4
ENST00000617695.4
laminin subunit alpha 2
chr9_+_136327526 0.53 ENST00000440944.6
G protein signaling modulator 1
chr21_+_7744971 0.52 ENST00000622934.3
ENST00000619874.4
ENST00000612624.4
ENST00000624304.3
ENST00000624758.3
small integral membrane protein 11B
chr1_+_2073688 0.50 ENST00000495347.5
protein kinase C zeta
chr19_+_7888499 0.50 ENST00000618098.4
ENST00000306708.11
ENST00000600345.1
ENST00000598224.5
leucine rich repeat containing 8 VRAC subunit E
chr2_-_187513641 0.50 ENST00000392365.5
ENST00000435414.5
tissue factor pathway inhibitor
chr1_-_235128819 0.49 ENST00000366607.5
translocase of outer mitochondrial membrane 20
chr11_+_83193704 0.48 ENST00000533342.6
ENST00000393389.7
ENST00000528722.5
ankyrin repeat domain 42
chr8_-_144475808 0.47 ENST00000377317.5
forkhead box H1
chr9_+_136327424 0.47 ENST00000616132.4
G protein signaling modulator 1
chr11_+_83193816 0.47 ENST00000260047.10
ankyrin repeat domain 42
chr4_-_74038681 0.46 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr17_+_8039034 0.43 ENST00000572022.5
ENST00000380173.6
ENST00000380183.9
arachidonate 15-lipoxygenase type B
chr6_-_79234619 0.42 ENST00000344726.9
ENST00000275036.11
high mobility group nucleosomal binding domain 3
chr8_+_73976182 0.42 ENST00000312184.6
ENST00000517439.1
transmembrane protein 70
chr2_-_156332694 0.42 ENST00000424077.1
ENST00000426264.5
ENST00000421709.1
ENST00000339562.9
nuclear receptor subfamily 4 group A member 2
chr9_-_137028878 0.41 ENST00000625103.1
ENST00000614293.4
ATP binding cassette subfamily A member 2
chr14_+_58244821 0.41 ENST00000216455.9
ENST00000412908.6
ENST00000557508.5
proteasome 20S subunit alpha 3
chrX_+_102712471 0.40 ENST00000652409.1
ARMCX5-GPRASP2 readthrough
chr20_-_63653413 0.38 ENST00000370053.3
stathmin 3
chr21_+_34375500 0.38 ENST00000399299.5
ENST00000399292.8
ENST00000474455.1
ENST00000399295.2
small integral membrane protein 11A
chr10_+_93993897 0.37 ENST00000371380.8
phospholipase C epsilon 1
chr17_-_39688016 0.37 ENST00000579146.5
ENST00000300658.9
ENST00000378011.8
ENST00000429199.6
post-GPI attachment to proteins phospholipase 3
chr15_+_47759723 0.36 ENST00000559196.1
semaphorin 6D
chr19_+_38899946 0.36 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKB inhibitor beta
chr14_-_88551460 0.36 ENST00000555243.1
protein tyrosine phosphatase non-receptor type 21
chr10_-_123891742 0.35 ENST00000241305.4
ENST00000615851.4
carboxypeptidase X, M14 family member 2
chr1_+_13584262 0.34 ENST00000376061.8
ENST00000513143.5
podoplanin
chr19_-_6110463 0.34 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000303657.10
ENST00000589742.5
ENST00000592546.5
regulatory factor X2
chr4_+_87422800 0.32 ENST00000440591.6
nudix hydrolase 9
chr1_-_109389886 0.31 ENST00000493736.5
sortilin 1
chr4_-_139084289 0.30 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chr13_-_94596145 0.29 ENST00000261296.7
TDP-glucose 4,6-dehydratase
chr8_-_22131003 0.27 ENST00000381418.9
HR lysine demethylase and nuclear receptor corepressor
chr10_-_60141004 0.27 ENST00000355288.6
ankyrin 3
chr1_-_154206327 0.27 ENST00000368525.4
chromosome 1 open reading frame 189
chr8_-_22131043 0.26 ENST00000312841.9
HR lysine demethylase and nuclear receptor corepressor
chr19_-_38899800 0.26 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr10_-_112446734 0.24 ENST00000684507.1
zinc finger DHHC-type palmitoyltransferase 6
chr17_-_75940943 0.24 ENST00000636174.1
ENST00000586631.2
Fas binding factor 1
chr2_+_48617798 0.22 ENST00000448460.5
ENST00000437125.5
ENST00000430487.6
general transcription factor IIA subunit 1 like
chr10_-_124791812 0.22 ENST00000652548.1
ENST00000368836.7
EEF1A lysine methyltransferase 2
chrX_+_154429092 0.22 ENST00000619046.5
ATPase H+ transporting accessory protein 1
chr3_-_180989678 0.22 ENST00000491873.5
ENST00000382564.8
ENST00000486355.1
DnaJ heat shock protein family (Hsp40) member C19
chr1_-_23825402 0.22 ENST00000235958.4
ENST00000436439.6
ENST00000374490.8
3-hydroxy-3-methylglutaryl-CoA lyase
chr6_+_10747753 0.21 ENST00000612333.4
transmembrane protein 14B
chr6_+_10585748 0.21 ENST00000265012.5
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr5_+_79069754 0.20 ENST00000518666.5
ENST00000521567.1
ENST00000255192.8
betaine--homocysteine S-methyltransferase 2
chr15_-_55289756 0.20 ENST00000336787.6
RAB27A, member RAS oncogene family
chr1_-_2194753 0.20 ENST00000378546.9
ENST00000400919.7
FA core complex associated protein 20
chr2_-_106886000 0.20 ENST00000419159.2
ST6 beta-galactoside alpha-2,6-sialyltransferase 2
chr6_+_10747765 0.20 ENST00000461342.5
ENST00000475942.5
ENST00000379542.10
ENST00000379530.7
ENST00000473276.5
ENST00000481240.5
ENST00000467317.5
transmembrane protein 14B
chr1_+_170532131 0.18 ENST00000367762.2
ENST00000367763.8
golgin, RAB6 interacting
chr19_-_57709147 0.17 ENST00000512439.6
ENST00000684351.1
zinc finger protein 154
chr3_-_180989518 0.17 ENST00000479269.5
ENST00000646965.1
DnaJ heat shock protein family (Hsp40) member C19
chr8_+_49909783 0.16 ENST00000518864.5
syntrophin gamma 1
chr3_-_45796467 0.16 ENST00000353278.8
ENST00000456124.6
solute carrier family 6 member 20
chr7_+_139341311 0.16 ENST00000297534.7
ENST00000541515.3
formation of mitochondrial complex V assembly factor 1 homolog
FMC1-LUC7L2 readthrough
chr6_+_139028838 0.16 ENST00000461027.1
ABRA C-terminal like
chr2_-_232550537 0.14 ENST00000408957.7
tigger transposable element derived 1
chr17_-_75941035 0.13 ENST00000586717.5
Fas binding factor 1
chr13_+_30735523 0.13 ENST00000380490.5
arachidonate 5-lipoxygenase activating protein
chr16_-_62036399 0.13 ENST00000584337.5
cadherin 8
chr10_-_112446932 0.12 ENST00000682195.1
ENST00000683505.1
ENST00000683895.1
ENST00000682839.1
ENST00000682055.1
zinc finger DHHC-type palmitoyltransferase 6
chr17_-_81947233 0.11 ENST00000409745.2
myeloid associated differentiation marker like 2
chr10_-_60140515 0.11 ENST00000486349.2
ankyrin 3
chr3_-_170870033 0.10 ENST00000466674.5
ENST00000295830.13
ENST00000463836.1
ribosomal protein L22 like 1
chr1_+_34782259 0.10 ENST00000373362.3
gap junction protein beta 3
chr12_-_49189053 0.08 ENST00000550767.6
ENST00000546918.1
ENST00000679733.1
ENST00000552924.2
ENST00000301071.12
tubulin alpha 1a
chr19_-_38899529 0.08 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr17_-_79950828 0.08 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr6_+_139028680 0.08 ENST00000367660.4
ABRA C-terminal like
chr16_-_62036412 0.07 ENST00000577390.6
cadherin 8
chr19_-_38899710 0.07 ENST00000447739.1
ENST00000407552.5
sirtuin 2
chr2_+_241350087 0.07 ENST00000451310.1
septin 2
chr18_-_49491586 0.07 ENST00000584895.5
ENST00000580210.5
ENST00000579408.5
RPL17-C18orf32 readthrough
ribosomal protein L17
chr3_-_16513374 0.07 ENST00000451036.5
raftlin, lipid raft linker 1
chr10_-_112446891 0.06 ENST00000369404.3
ENST00000369405.7
ENST00000626395.2
zinc finger DHHC-type palmitoyltransferase 6
chr12_+_4649097 0.05 ENST00000648836.1
ENST00000266544.10
novel protein
NADH:ubiquinone oxidoreductase subunit A9
chr19_-_45782479 0.05 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DM1 protein kinase
chr2_+_218419114 0.05 ENST00000454069.5
ENST00000392114.6
ENST00000248444.10
villin 1
chr1_+_151198536 0.04 ENST00000349792.9
ENST00000409426.5
ENST00000368888.9
ENST00000441902.6
ENST00000368890.8
ENST00000424999.1
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
chr1_+_40258202 0.03 ENST00000372759.4
zinc metallopeptidase STE24
chr5_+_126600913 0.03 ENST00000297540.5
phosphorylated adaptor for RNA export
chr1_-_53838276 0.03 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr6_+_39793008 0.02 ENST00000398904.6
dishevelled associated activator of morphogenesis 2
chr17_+_8039106 0.01 ENST00000573359.1
arachidonate 15-lipoxygenase type B
chr4_+_39459039 0.01 ENST00000509519.5
ENST00000640888.2
ENST00000424936.6
ENST00000381846.2
ENST00000513731.6
lipoic acid synthetase
chr18_+_56651661 0.01 ENST00000593058.1
WD repeat domain 7
chr1_+_47333774 0.00 ENST00000371873.10
cytidine/uridine monophosphate kinase 1
chr1_+_47333863 0.00 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr10_+_112375196 0.00 ENST00000393081.6
acyl-CoA synthetase long chain family member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.3 3.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 2.3 GO:0021759 globus pallidus development(GO:0021759)
0.2 3.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.6 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2 1.9 GO:0006565 L-serine catabolic process(GO:0006565)
0.2 2.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 1.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.5 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.3 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.3 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.5 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 2.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.7 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.4 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 1.0 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 1.2 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 1.5 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.4 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0043102 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.9 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.0 GO:0080120 prenylated protein catabolic process(GO:0030327) CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 GO:0045179 apical cortex(GO:0045179)
0.1 1.2 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 5.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.6 1.9 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.2 1.2 GO:0070051 fibrinogen binding(GO:0070051)
0.2 1.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 0.5 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.4 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.4 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 2.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 0.3 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.1 3.2 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 0.3 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.6 GO:0089720 caspase binding(GO:0089720)
0.1 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 2.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.0 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL