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Illumina Body Map 2 (GSE30611)

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Results for ZNF35

Z-value: 0.42

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Transcription factors associated with ZNF35

Gene Symbol Gene ID Gene Info
ZNF35
ENSG00000169981.11 zinc finger protein 35

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF35hg38_v1_chr3_+_44648719_44648776-0.077.1e-01Click!

Activity profile of ZNF35 motif

Sorted Z-values of ZNF35 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_126656128 0.60 ENST00000259254.9
ENST00000409836.3
ENST00000356887.12
GYPC
glycophorin C (Gerbich blood group)
chr10_+_61901678 0.56 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
ARID5B
AT-rich interaction domain 5B
chr3_-_49029378 0.54 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
IMPDH2
inosine monophosphate dehydrogenase 2
chr16_-_4273014 0.51 ENST00000204517.11
TFAP4
transcription factor AP-4
chr12_+_54497712 0.49 ENST00000293373.11
NCKAP1L
NCK associated protein 1 like
chr19_-_4535221 0.48 ENST00000381848.7
ENST00000586133.1
PLIN5
perilipin 5
chr4_-_44651619 0.45 ENST00000415895.9
ENST00000332990.6
YIPF7
Yip1 domain family member 7
chr8_-_94262308 0.44 ENST00000297596.3
ENST00000396194.6
GEM
GTP binding protein overexpressed in skeletal muscle
chr3_-_132684685 0.43 ENST00000512094.5
ENST00000632629.1
NPHP3
NPHP3-ACAD11
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chr2_-_189580773 0.39 ENST00000261024.7
SLC40A1
solute carrier family 40 member 1
chr2_-_216695540 0.39 ENST00000233813.5
IGFBP5
insulin like growth factor binding protein 5
chr15_+_45634721 0.37 ENST00000561735.5
SQOR
sulfide quinone oxidoreductase
chr19_+_47608942 0.37 ENST00000594866.2
BICRA
BRD4 interacting chromatin remodeling complex associated protein
chr6_+_156776020 0.27 ENST00000346085.10
ARID1B
AT-rich interaction domain 1B
chr7_+_27242796 0.26 ENST00000496902.7
EVX1
even-skipped homeobox 1
chr10_+_24042131 0.25 ENST00000636305.1
KIAA1217
KIAA1217
chr3_-_149221811 0.24 ENST00000455472.3
ENST00000264613.11
CP
ceruloplasmin
chr3_+_69936629 0.23 ENST00000394348.2
ENST00000531774.1
MITF
melanocyte inducing transcription factor
chr16_-_77431553 0.23 ENST00000562345.1
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif 18
chr1_+_61404076 0.22 ENST00000357977.5
NFIA
nuclear factor I A
chr4_+_67558719 0.22 ENST00000265404.7
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr11_+_111245725 0.22 ENST00000280325.7
C11orf53
chromosome 11 open reading frame 53
chr8_-_144529048 0.22 ENST00000527462.1
ENST00000313465.5
ENST00000524821.6
C8orf82
chromosome 8 open reading frame 82
chr14_+_19875142 0.21 ENST00000641885.1
OR4K2
olfactory receptor family 4 subfamily K member 2
chr3_+_69936583 0.21 ENST00000314557.10
ENST00000394351.9
MITF
melanocyte inducing transcription factor
chr10_+_72893572 0.20 ENST00000622652.1
OIT3
oncoprotein induced transcript 3
chr2_+_147845020 0.19 ENST00000241416.12
ACVR2A
activin A receptor type 2A
chr3_-_71583592 0.19 ENST00000650156.1
ENST00000649596.1
FOXP1
forkhead box P1
chr7_+_27242700 0.19 ENST00000222761.7
EVX1
even-skipped homeobox 1
chr5_+_76875177 0.19 ENST00000613039.1
S100Z
S100 calcium binding protein Z
chr16_+_8621679 0.18 ENST00000563958.5
ENST00000381920.8
ENST00000564554.1
METTL22
methyltransferase like 22
chr7_+_123848070 0.18 ENST00000476325.5
HYAL4
hyaluronidase 4
chr4_+_73436198 0.17 ENST00000395792.7
AFP
alpha fetoprotein
chr12_-_10939263 0.17 ENST00000537503.2
TAS2R14
taste 2 receptor member 14
chr3_-_146605239 0.16 ENST00000492200.5
ENST00000482567.5
ENST00000443512.2
PLSCR5
phospholipid scramblase family member 5
chr4_+_73436244 0.16 ENST00000226359.2
AFP
alpha fetoprotein
chr1_+_84164962 0.15 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr13_-_35855758 0.15 ENST00000615680.4
DCLK1
doublecortin like kinase 1
chr5_-_39202991 0.15 ENST00000515010.5
FYB1
FYN binding protein 1
chr3_-_71583713 0.14 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
FOXP1
forkhead box P1
chr3_-_71493500 0.14 ENST00000648380.1
ENST00000650295.1
FOXP1
forkhead box P1
chr16_+_14833713 0.14 ENST00000287667.12
ENST00000620755.4
ENST00000610363.4
NOMO1
NODAL modulator 1
chrM_+_4467 0.14 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr12_-_102478539 0.13 ENST00000424202.6
IGF1
insulin like growth factor 1
chr13_-_35855627 0.13 ENST00000379893.5
DCLK1
doublecortin like kinase 1
chr4_+_173370908 0.13 ENST00000296504.4
SAP30
Sin3A associated protein 30
chr13_-_46897021 0.13 ENST00000542664.4
ENST00000543956.5
HTR2A
5-hydroxytryptamine receptor 2A
chr19_+_49591170 0.12 ENST00000418929.7
PRR12
proline rich 12
chr17_-_65561640 0.12 ENST00000618960.4
ENST00000307078.10
AXIN2
axin 2
chr7_+_80602150 0.12 ENST00000309881.11
CD36
CD36 molecule
chr6_-_132763424 0.12 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
VNN2
vanin 2
chr17_-_445939 0.12 ENST00000329099.4
RFLNB
refilin B
chr19_-_14090695 0.11 ENST00000533683.7
SAMD1
sterile alpha motif domain containing 1
chr3_+_141387616 0.11 ENST00000509883.5
ZBTB38
zinc finger and BTB domain containing 38
chr17_+_43483949 0.10 ENST00000540306.5
ENST00000262415.8
DHX8
DEAH-box helicase 8
chr10_-_50885619 0.10 ENST00000373997.8
A1CF
APOBEC1 complementation factor
chr9_-_16705062 0.10 ENST00000471301.3
BNC2
basonuclin 2
chr5_+_140112870 0.09 ENST00000502351.1
PURA
purine rich element binding protein A
chr1_-_169703329 0.09 ENST00000497295.1
SELL
selectin L
chr12_+_55314343 0.08 ENST00000642104.1
OR6C1
olfactory receptor family 6 subfamily C member 1
chr17_-_59151794 0.08 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr20_+_58907981 0.08 ENST00000656419.1
GNAS
GNAS complex locus
chr12_-_22334683 0.07 ENST00000404299.3
ENST00000396037.9
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr12_-_22334637 0.07 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr11_+_57667747 0.07 ENST00000527985.5
ZDHHC5
zinc finger DHHC-type palmitoyltransferase 5
chr3_+_184035104 0.07 ENST00000453435.1
HTR3D
5-hydroxytryptamine receptor 3D
chr19_+_926001 0.07 ENST00000263620.8
ARID3A
AT-rich interaction domain 3A
chr2_+_191678152 0.06 ENST00000409510.5
NABP1
nucleic acid binding protein 1
chr2_-_80304274 0.06 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr4_+_74308487 0.06 ENST00000332112.8
EPGN
epithelial mitogen
chr1_+_84164891 0.06 ENST00000413538.5
ENST00000417530.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr6_+_96563117 0.05 ENST00000450218.6
FHL5
four and a half LIM domains 5
chr17_+_7438267 0.05 ENST00000575235.5
FGF11
fibroblast growth factor 11
chr4_+_94455245 0.05 ENST00000508216.5
ENST00000514743.5
PDLIM5
PDZ and LIM domain 5
chr4_-_88823214 0.05 ENST00000513837.5
ENST00000503556.5
FAM13A
family with sequence similarity 13 member A
chr2_-_70182786 0.04 ENST00000419381.1
C2orf42
chromosome 2 open reading frame 42
chr4_-_145938473 0.04 ENST00000513320.5
ZNF827
zinc finger protein 827
chr3_+_141386862 0.04 ENST00000513258.5
ZBTB38
zinc finger and BTB domain containing 38
chr10_-_50885656 0.03 ENST00000374001.6
ENST00000395489.6
ENST00000282641.6
ENST00000395495.5
ENST00000373995.7
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr20_-_10420737 0.03 ENST00000649912.1
ENSG00000285723.1
novel protein
chr4_+_74308492 0.03 ENST00000502358.5
ENST00000503098.5
ENST00000505212.5
ENST00000509145.5
ENST00000514968.5
EPGN
epithelial mitogen
chr7_-_78771058 0.03 ENST00000628781.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_145938422 0.03 ENST00000656985.1
ENST00000652097.1
ENST00000503462.3
ENST00000379448.9
ENST00000513840.2
ZNF827
zinc finger protein 827
chr4_-_145938775 0.03 ENST00000508784.6
ZNF827
zinc finger protein 827
chr12_-_46372763 0.03 ENST00000256689.10
SLC38A2
solute carrier family 38 member 2
chr7_-_78771108 0.02 ENST00000626691.2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_-_10410094 0.02 ENST00000475264.5
TFAP2A
transcription factor AP-2 alpha
chr1_-_151327365 0.01 ENST00000438243.2
ENST00000489223.2
ENST00000368873.6
ENST00000430800.5
ENST00000368872.5
PI4KB
phosphatidylinositol 4-kinase beta
chr2_+_66435558 0.01 ENST00000488550.5
MEIS1
Meis homeobox 1
chr13_-_46020487 0.00 ENST00000464597.2
ZC3H13
zinc finger CCCH-type containing 13
chr13_-_52848632 0.00 ENST00000377942.7
ENST00000338862.5
PCDH8
protocadherin 8

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF35

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.4 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.4 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.4 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.0 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097689 iron channel activity(GO:0097689)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.5 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711) BMP receptor activity(GO:0098821)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters