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Illumina Body Map 2 (GSE30611)

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Results for ZNF423

Z-value: 0.94

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Transcription factors associated with ZNF423

Gene Symbol Gene ID Gene Info
ZNF423
ENSG00000102935.12 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF423hg38_v1_chr16_-_49664225_496642980.612.2e-04Click!

Activity profile of ZNF423 motif

Sorted Z-values of ZNF423 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_71358713 4.45 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
CALB2
calbindin 2
chr5_+_151020438 2.96 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
GPX3
glutathione peroxidase 3
chr8_+_30384511 2.53 ENST00000339877.8
ENST00000320203.8
ENST00000287771.9
ENST00000397323.9
RBPMS
RNA binding protein, mRNA processing factor
chr1_-_32901330 2.26 ENST00000329151.5
ENST00000373463.8
TMEM54
transmembrane protein 54
chr19_-_15200902 2.15 ENST00000601011.1
ENST00000263388.7
NOTCH3
notch receptor 3
chr11_-_61295289 2.14 ENST00000335613.10
VWCE
von Willebrand factor C and EGF domains
chr1_+_53062052 2.11 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
PODN
podocan
chr17_+_79024142 1.92 ENST00000579760.6
ENST00000339142.6
C1QTNF1
C1q and TNF related 1
chr6_+_168441136 1.81 ENST00000354536.9
SMOC2
SPARC related modular calcium binding 2
chr6_+_168441170 1.79 ENST00000356284.7
SMOC2
SPARC related modular calcium binding 2
chr5_+_53480619 1.67 ENST00000396947.7
ENST00000256759.8
FST
follistatin
chr17_+_79024243 1.55 ENST00000311661.4
C1QTNF1
C1q and TNF related 1
chr2_+_14632688 1.53 ENST00000331243.4
ENST00000295092.3
LRATD1
LRAT domain containing 1
chr9_+_35909481 1.48 ENST00000443779.3
SPAAR
small regulatory polypeptide of amino acid response
chr1_-_227318453 1.44 ENST00000366769.7
ENST00000366766.7
CDC42BPA
CDC42 binding protein kinase alpha
chr11_+_60924452 1.43 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chrX_-_48971829 1.25 ENST00000218176.4
KCND1
potassium voltage-gated channel subfamily D member 1
chr4_+_6277309 1.25 ENST00000684087.1
ENST00000674051.1
ENST00000682059.1
ENST00000684054.1
ENST00000684700.1
ENST00000683395.1
WFS1
wolframin ER transmembrane glycoprotein
chr9_-_16870702 1.23 ENST00000380667.6
ENST00000545497.5
ENST00000486514.5
BNC2
basonuclin 2
chr9_+_109780312 1.20 ENST00000483909.5
ENST00000413420.5
ENST00000302798.7
PALM2AKAP2
PALM2 and AKAP2 fusion
chr9_+_109780292 1.18 ENST00000374530.7
PALM2AKAP2
PALM2 and AKAP2 fusion
chrX_-_51496572 1.17 ENST00000375992.4
NUDT11
nudix hydrolase 11
chr14_+_99737689 1.17 ENST00000554479.5
ENST00000555145.5
EML1
EMAP like 1
chr16_-_70685975 1.15 ENST00000338779.11
MTSS2
MTSS I-BAR domain containing 2
chr11_-_44950839 1.09 ENST00000395648.7
ENST00000531928.6
TP53I11
tumor protein p53 inducible protein 11
chr20_+_31475278 1.08 ENST00000201979.3
REM1
RRAD and GEM like GTPase 1
chr8_+_22565655 1.08 ENST00000523965.5
SORBS3
sorbin and SH3 domain containing 3
chr8_+_22565236 0.98 ENST00000523900.5
SORBS3
sorbin and SH3 domain containing 3
chr2_+_62705644 0.98 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EHBP1
EH domain binding protein 1
chr7_-_27180230 0.97 ENST00000396344.4
HOXA10
homeobox A10
chr9_-_16870662 0.96 ENST00000380672.9
BNC2
basonuclin 2
chr10_+_84173793 0.95 ENST00000372126.4
C10orf99
chromosome 10 open reading frame 99
chr1_-_155207886 0.94 ENST00000368378.7
ENST00000541990.5
ENST00000457183.6
ENST00000541576.5
THBS3
thrombospondin 3
chr11_-_44950867 0.92 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
TP53I11
tumor protein p53 inducible protein 11
chr12_+_54016879 0.88 ENST00000303406.4
HOXC4
homeobox C4
chr10_-_98268186 0.88 ENST00000260702.4
LOXL4
lysyl oxidase like 4
chr16_-_70685791 0.84 ENST00000616026.4
MTSS2
MTSS I-BAR domain containing 2
chr4_+_6277519 0.82 ENST00000673642.1
WFS1
wolframin ER transmembrane glycoprotein
chr19_+_45467988 0.82 ENST00000615753.4
ENST00000585836.5
ENST00000417353.6
ENST00000591858.5
ENST00000443841.6
ENST00000590335.1
ENST00000353609.8
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit
chr8_-_79767462 0.82 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr1_-_204151884 0.81 ENST00000367201.7
ETNK2
ethanolamine kinase 2
chr22_-_42649332 0.80 ENST00000352397.10
CYB5R3
cytochrome b5 reductase 3
chr11_-_44950731 0.80 ENST00000528473.5
TP53I11
tumor protein p53 inducible protein 11
chr19_+_14433284 0.79 ENST00000242783.11
PKN1
protein kinase N1
chr11_-_44950151 0.78 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr11_-_1036706 0.77 ENST00000421673.7
MUC6
mucin 6, oligomeric mucus/gel-forming
chr9_-_127897399 0.75 ENST00000542456.5
ENST00000373141.5
ST6GALNAC6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr11_-_61891534 0.75 ENST00000278829.7
FADS3
fatty acid desaturase 3
chr20_-_38166500 0.74 ENST00000373403.7
TGM2
transglutaminase 2
chr20_+_45834112 0.72 ENST00000372541.1
SNX21
sorting nexin family member 21
chr1_-_204152010 0.70 ENST00000367202.9
ETNK2
ethanolamine kinase 2
chr20_-_38166538 0.68 ENST00000453095.1
TGM2
transglutaminase 2
chr8_+_22165358 0.66 ENST00000306349.13
ENST00000306385.10
BMP1
bone morphogenetic protein 1
chr9_-_39239174 0.64 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chr11_+_61828280 0.64 ENST00000521849.5
ENST00000278840.9
FADS2
fatty acid desaturase 2
chr8_+_22165140 0.60 ENST00000397814.7
ENST00000354870.5
BMP1
bone morphogenetic protein 1
chr19_+_14433384 0.60 ENST00000586557.5
ENST00000590097.5
PKN1
protein kinase N1
chr7_+_20330893 0.58 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr12_-_49707220 0.55 ENST00000550488.5
FMNL3
formin like 3
chr19_-_56671746 0.55 ENST00000537055.4
ENST00000601659.1
ZNF835
zinc finger protein 835
chr19_+_6740878 0.55 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr15_-_89751292 0.54 ENST00000300057.4
MESP1
mesoderm posterior bHLH transcription factor 1
chr11_+_832887 0.54 ENST00000524748.6
ENST00000397420.9
ENST00000397421.5
ENST00000322008.9
ENST00000525718.6
ENST00000529810.5
ENST00000526693.5
ENST00000525333.5
ENST00000527341.5
CD151
CD151 molecule (Raph blood group)
chr11_-_61891381 0.53 ENST00000525588.5
FADS3
fatty acid desaturase 3
chr19_+_41264345 0.53 ENST00000378215.8
ENST00000392006.8
ENST00000617774.1
ENST00000602130.5
ENST00000617305.4
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U like 1
chr2_+_27496830 0.52 ENST00000264717.7
GCKR
glucokinase regulator
chr9_+_127398161 0.50 ENST00000439597.5
ENST00000423934.5
SLC2A8
solute carrier family 2 member 8
chr13_+_51222391 0.50 ENST00000322475.13
FAM124A
family with sequence similarity 124 member A
chr18_-_5543988 0.49 ENST00000341928.7
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr19_-_5622768 0.48 ENST00000252542.9
SAFB2
scaffold attachment factor B2
chr8_-_79767843 0.46 ENST00000337919.9
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr7_-_5530581 0.46 ENST00000676397.1
ENST00000645576.1
ENST00000674681.1
ENST00000646664.1
ENST00000493945.6
ENST00000676319.1
ENST00000473257.3
ENST00000647275.1
ENST00000432588.6
ACTB
actin beta
chr12_-_49707368 0.45 ENST00000352151.9
ENST00000335154.10
FMNL3
formin like 3
chr12_+_50057548 0.43 ENST00000228468.8
ENST00000447966.7
ASIC1
acid sensing ion channel subunit 1
chr10_+_112950240 0.42 ENST00000627217.3
ENST00000534894.5
ENST00000538897.5
ENST00000536810.5
ENST00000355995.8
ENST00000542695.5
ENST00000543371.5
TCF7L2
transcription factor 7 like 2
chr11_-_107858777 0.40 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr21_-_17612842 0.39 ENST00000339775.10
ENST00000348354.7
BTG3
BTG anti-proliferation factor 3
chr1_+_26993684 0.39 ENST00000522111.3
TRNP1
TMF1 regulated nuclear protein 1
chr19_-_46714269 0.39 ENST00000600194.5
PRKD2
protein kinase D2
chr3_+_9917074 0.37 ENST00000416074.6
ENST00000383812.9
ENST00000438091.5
ENST00000295981.7
ENST00000403601.8
ENST00000436503.5
ENST00000455057.5
IL17RC
interleukin 17 receptor C
chr11_-_68980986 0.36 ENST00000309106.3
MRGPRD
MAS related GPR family member D
chr5_+_69492767 0.35 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
OCLN
occludin
chr4_-_119628007 0.35 ENST00000420633.1
ENST00000394439.5
PDE5A
phosphodiesterase 5A
chr5_-_139482341 0.31 ENST00000651699.1
STING1
stimulator of interferon response cGAMP interactor 1
chr11_+_61828094 0.30 ENST00000517312.5
FADS2
fatty acid desaturase 2
chr3_+_138349209 0.29 ENST00000474559.1
MRAS
muscle RAS oncogene homolog
chr19_+_35533436 0.29 ENST00000222286.9
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr19_-_11578937 0.28 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
ACP5
acid phosphatase 5, tartrate resistant
chr20_+_33993904 0.27 ENST00000246194.8
RALY
RALY heterogeneous nuclear ribonucleoprotein
chr9_+_113876282 0.26 ENST00000374126.9
ENST00000615615.4
ENST00000288466.11
ZNF618
zinc finger protein 618
chr3_-_196082078 0.26 ENST00000360110.9
ENST00000392396.7
ENST00000420415.5
TFRC
transferrin receptor
chr19_-_49867251 0.26 ENST00000631020.2
ENST00000596014.5
ENST00000636994.1
PNKP
polynucleotide kinase 3'-phosphatase
chr15_-_75368578 0.25 ENST00000569482.5
ENST00000565683.5
ENST00000561615.1
ENST00000563622.5
ENST00000568374.5
ENST00000267978.10
ENST00000566256.5
MAN2C1
mannosidase alpha class 2C member 1
chr9_+_98807619 0.24 ENST00000375011.4
GALNT12
polypeptide N-acetylgalactosaminyltransferase 12
chr3_+_9917185 0.23 ENST00000413608.2
ENST00000451165.6
IL17RC
interleukin 17 receptor C
chr9_+_136354776 0.22 ENST00000392944.5
GPSM1
G protein signaling modulator 1
chr1_+_155308748 0.21 ENST00000611010.4
ENST00000447866.5
ENST00000368356.9
ENST00000467076.5
ENST00000491013.5
ENST00000356657.10
FDPS
farnesyl diphosphate synthase
chr5_+_169584029 0.20 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr5_+_169583636 0.20 ENST00000506574.5
ENST00000515224.5
ENST00000629457.2
ENST00000508247.5
ENST00000265295.9
ENST00000513941.5
SPDL1
spindle apparatus coiled-coil protein 1
chr19_-_11481044 0.18 ENST00000359227.8
ELAVL3
ELAV like RNA binding protein 3
chr1_+_1512137 0.17 ENST00000378756.8
ENST00000378755.9
ATAD3A
ATPase family AAA domain containing 3A
chr4_-_119627631 0.17 ENST00000264805.9
PDE5A
phosphodiesterase 5A
chr6_+_33621313 0.17 ENST00000605930.3
ITPR3
inositol 1,4,5-trisphosphate receptor type 3
chr19_-_55599493 0.17 ENST00000221665.5
ENST00000592585.1
FIZ1
FLT3 interacting zinc finger 1
chr1_+_155308930 0.16 ENST00000465559.5
ENST00000612683.1
FDPS
farnesyl diphosphate synthase
chr22_+_35257452 0.15 ENST00000420166.5
ENST00000216106.6
ENST00000455359.5
HMGXB4
HMG-box containing 4
chr12_+_52079700 0.15 ENST00000546390.2
SMIM41
small integral membrane protein 41
chr9_-_96619783 0.14 ENST00000375241.6
CDC14B
cell division cycle 14B
chr9_-_128724088 0.14 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
ZDHHC12
zinc finger DHHC-type palmitoyltransferase 12
chr20_-_25082131 0.14 ENST00000429762.7
ENST00000444511.6
ENST00000376707.4
ENST00000376709.9
VSX1
visual system homeobox 1
chr11_-_63917129 0.13 ENST00000301459.5
RCOR2
REST corepressor 2
chrX_+_106920393 0.13 ENST00000336803.2
CLDN2
claudin 2
chr2_+_227616998 0.12 ENST00000641801.1
SCYGR4
small cysteine and glycine repeat containing 4
chr1_-_165445220 0.12 ENST00000619224.1
RXRG
retinoid X receptor gamma
chr16_+_27313879 0.11 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
IL4R
interleukin 4 receptor
chr12_+_7189675 0.11 ENST00000675855.1
ENST00000434354.6
ENST00000544456.5
ENST00000545574.5
ENST00000420616.6
PEX5
peroxisomal biogenesis factor 5
chr18_-_63318674 0.11 ENST00000589955.2
BCL2
BCL2 apoptosis regulator
chr10_-_73495966 0.10 ENST00000342558.3
ENST00000360663.10
ENST00000394828.6
ENST00000394829.6
PPP3CB
protein phosphatase 3 catalytic subunit beta
chr19_+_45251363 0.10 ENST00000620044.4
MARK4
microtubule affinity regulating kinase 4
chr6_-_31112566 0.10 ENST00000259870.4
C6orf15
chromosome 6 open reading frame 15
chr1_+_1471751 0.09 ENST00000673477.1
ENST00000308647.8
ATAD3B
ATPase family AAA domain containing 3B
chr12_+_7189582 0.09 ENST00000266563.9
ENST00000543974.5
PEX5
peroxisomal biogenesis factor 5
chr7_-_23014074 0.09 ENST00000409763.1
ENST00000679826.1
ENST00000409923.5
ENST00000681766.1
FAM126A
family with sequence similarity 126 member A
chr7_+_20330678 0.08 ENST00000537992.5
ITGB8
integrin subunit beta 8
chrX_+_30247139 0.08 ENST00000397548.4
MAGEB1
MAGE family member B1
chr5_+_136049513 0.07 ENST00000514554.5
TGFBI
transforming growth factor beta induced
chr9_+_128787331 0.07 ENST00000223865.8
TBC1D13
TBC1 domain family member 13
chrX_-_18354672 0.07 ENST00000251900.9
SCML2
Scm polycomb group protein like 2
chr1_-_35193135 0.06 ENST00000357214.6
SFPQ
splicing factor proline and glutamine rich
chr12_-_57129001 0.06 ENST00000556155.5
STAT6
signal transducer and activator of transcription 6
chr3_+_6861107 0.06 ENST00000357716.9
ENST00000486284.5
ENST00000389336.8
GRM7
glutamate metabotropic receptor 7
chr6_-_35512863 0.06 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TULP1
TUB like protein 1
chr8_-_42377227 0.06 ENST00000220812.3
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr6_-_142147122 0.05 ENST00000258042.2
NMBR
neuromedin B receptor
chr1_-_165445088 0.05 ENST00000359842.10
RXRG
retinoid X receptor gamma
chr1_-_101996919 0.04 ENST00000370103.9
OLFM3
olfactomedin 3
chr9_-_96619378 0.04 ENST00000375240.7
ENST00000463569.5
CDC14B
cell division cycle 14B
chr7_-_29989712 0.04 ENST00000425819.6
ENST00000409570.3
SCRN1
secernin 1
chr4_-_165112852 0.03 ENST00000505095.1
ENST00000306480.11
TMEM192
transmembrane protein 192
chr6_+_30884063 0.03 ENST00000511510.5
ENST00000376569.7
ENST00000376570.8
ENST00000504927.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr4_+_70704713 0.03 ENST00000417478.6
RUFY3
RUN and FYVE domain containing 3
chr15_-_58933668 0.03 ENST00000380516.7
SLTM
SAFB like transcription modulator
chr7_-_100656384 0.02 ENST00000461605.1
ENST00000160382.10
ACTL6B
actin like 6B
chr9_-_37904085 0.02 ENST00000377716.6
ENST00000242275.7
SLC25A51
solute carrier family 25 member 51
chr16_-_85112390 0.02 ENST00000629253.1
ENST00000539556.6
CIBAR2
CBY1 interacting BAR domain containing 2
chr20_+_44401222 0.02 ENST00000316099.9
HNF4A
hepatocyte nuclear factor 4 alpha
chr6_-_35512882 0.01 ENST00000229771.11
TULP1
TUB like protein 1
chr8_-_143160603 0.00 ENST00000615409.1
ENST00000414417.6
LY6H
lymphocyte antigen 6 family member H

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF423

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.5 3.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4 1.3 GO:0061027 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.4 3.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.4 1.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 1.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 1.2 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.5 GO:0090381 cardiac cell fate determination(GO:0060913) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.2 2.2 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 2.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 1.5 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.3 GO:0000718 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) DNA 3' dephosphorylation(GO:0098503) DNA 3' dephosphorylation involved in DNA repair(GO:0098504) polynucleotide 3' dephosphorylation(GO:0098506)
0.1 3.1 GO:0003416 endochondral bone growth(GO:0003416)
0.1 0.4 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 1.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.5 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 1.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.3 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 1.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0089700 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700)
0.0 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.8 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.9 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.4 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.8 GO:0051412 response to corticosterone(GO:0051412)
0.0 2.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 2.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.0 GO:0060065 uterus development(GO:0060065)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.9 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.5 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 3.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.2 GO:0007405 neuroblast proliferation(GO:0007405)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.2 0.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 3.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 4.4 GO:0005921 gap junction(GO:0005921)
0.1 2.5 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.8 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 3.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 2.1 GO:0000502 proteasome complex(GO:0000502)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 1.3 GO:0035939 microsatellite binding(GO:0035939)
0.2 1.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 1.2 GO:0052842 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 0.9 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.2 1.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 1.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.5 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 3.0 GO:0008430 selenium binding(GO:0008430)
0.1 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.3 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 1.7 GO:0048185 activin binding(GO:0048185)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 2.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 1.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 5.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 4.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.4 PID BMP PATHWAY BMP receptor signaling
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 2.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription